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Marco Alexandre Dias da Rocha,1 Markéta Saint Aroman,2 Valérie Mengeaud,3 Fabienne Carballido,4 Gautier Doat,5 Ana Coutinho,6 Edileia Bagatin1 1Department of Dermatology, Universidade Federal de São Paulo, São Paulo, Brazil; 2Corporate Medical Direction Dermocosmetics Care & Personal Care, Pierre Fabre, Toulouse, France; 3Laboratoires Dermatologiques Ducray, Pierre Fabre Dermo-Cosmétique, Lavaur, France; 4Laboratoires Dermatologiques A-Derma, Pierre Fabre Dermo-Cosmétique, Lavaur, France; 5Laboratoires Dermatologiques Avène, Pierre Fabre Dermo-Cosmétique, Lavaur, France; 6Laboratorios Pierre Fabre do Brasil LTDA, Rio de Janeiro, BrazilCorrespondence: Marco Alexandre Dias da Rocha, Departamento de Dermatologia, Universidade Federal de São Paulo (UNIFESP), R. Botucatu, 821 - Vila Clementino, São Paulo, SP, 04039-001, Brazil, Tel +55-(11)-3129-5007, Email marcoderm@hotmail.comAbstract: Previously considered a skin disease exclusively affecting adolescents, characterized by inflammatory and non-inflammatory skin lesions, acne vulgaris is now increasingly observed in adult life, including post-menopause. Today, adult female acne (AFA) is a common chronic inflammatory disease of the pilosebaceous unit, with polymorphic lesions presenting as open or closed comedones, papules, pustules, and even nodules or cysts, often with the presence of sequelae. AFA may persist from adolescence or manifest de novo in adulthood. Its etiology is multifactorial, involving genetic, hormonal, dietary, and environmental factors, yet still incompletely understood. Increased sebum production, keratinocyte hyper-proliferation, inflammation, and reduced diversity of Cutibacterium acnes strains are the underlying disease mechanisms. During menopausal transition, a relative increase in androgen levels occurs, just as estrogens begin to decline, which can manifest itself as acne. Whereas most AFA exhibit few acne lesions with normo-androgenic serum levels, baseline investigations including androgen testing panel enable associated comorbidities to be eliminated, such as polycystic ovarian syndrome, congenital adrenal hyperplasia, or tumors. Another interesting feature is AFA’s impact on quality of life, which is greater than in adolescents, being similar to other chronic diseases like asthma. The therapeutic approach to AFA depends on its severity and associated features. This review investigates the intricate facets of AFA, with a specific focus on incidence rates, treatment modalities, and the curious impact of menopause. Utilizing insights from contemporary literature and scientific discussions, this article seeks to advance our understanding of AFA, offering new perspectives to shape clinical practices and improve patient outcomes.Keywords: adult female acne, epidemiology, treatment, dermocosmetics, menopause, hormonal dynamics

Alison M Layton,1 Marco Alexandre Dias da Rocha2 1Skin Research Centre, Hull York Medical School, University of Hull, Hull, UK; 2Federal University of São Paulo, São Paulo, BrazilCorrespondence: Marco Alexandre Dias da Rocha, Federal University of São Paulo, Rua Oscar Pinheiro Coelho, 115 casa 04. Caxingui, São Paulo, Brazil, Email marcoderm@hotmail.comAbstract: Acne Vulgaris is a chronic inflammatory skin disease, and one of the most prevalent inflammatory dermatoses among teenagers, affecting more than > 95% of boys and 85% of girls. Adult female acne (AFA) is a subtype of acne, pragmatically defined as affecting women over the age of 25. The clinical presentation of AFA may be distinguished from adolescent acne according to some key clinical and psychosocial characteristics. The etiopathogenic factors and the chronic clinical course that are implicated in AFA make management complex and challenging. A frequent tendency to relapse makes the requirement for maintenance therapy highly likely. Therefore, AFA typically requires a specific, tailored therapeutic approach. This paper presents six challenging case studies that demonstrate the efficacy of azelaic acid gel (AZA) in adult female acne. The six cases use AZA as monotherapy, as part of a combination regimen at treatment initiation, or as maintenance treatment (which is frequently required in this adult population). The positive outcomes achieved in this case series demonstrate that AZA can be efficacious, result in excellent patient satisfaction in mild to moderate adult female acne, and can be effective as a maintenance therapy.Keywords: acne vulgaris, adult female acne, azelaic acid, skin conditions, inflammation

Scholars' engagement with digital social networks is complex, warranting a comprehensive understanding of their use and participation. Current research has not yet grasped the motivators, gratification, and challenges that academics encounter across multiple digital social networks. With this in mind, this study surveyed scholars who purposely participate in digital social networks for professional endeavors. The theoretical frameworks guiding this research are the Uses and Gratification framework and the networked participatory scholarship conceptualization. A total of 307 higher education scholars completed an electronic survey with closed and open-ended questions. Data analysis included descriptive statistics and a team-coding approach for qualitative data. The results of this investigation highlight specific motivators for using digital social networks to support the scholar's teaching, research, and professional development. The results of this investigation suggest that scholars are constantly navigating challenges and trading them off against the benefits. The results of this investigation also helped determine the imagined audiences that scholars perceive as potential spectators when using digital social networks for their scholarly efforts. The results illustrate the many reasons provided by scholars, which aligned with the self-presentation and impression management theory.

Several studies have explored the uses and benefits of social media hashtag communities in higher education… Yet, more research is needed to examine communication structures and strategies for personal branding in educational social media hashtag communities. In other words, to understand the dynamics, characteristics, and strategies for faculty, university staff, and graduate students need to brand themselves professionally in social media hashtag communities. This research aims to explore social network structures, dynamics, influencer characteristics, and personal branding strategies of the #AcademicTwitter online community. X (formerly known as Twitter) data on #AcademicTwitter from 2021 were retrieved and analysed using social network and quantitative content analysis. Our study found that most of the recurrent users in the community were scholars (faculty and researchers) predominantly from the STEM field. However, the most influential users were media/fan pages (a profile account created for different purposes such as sharing tips in academia, publishers, etc.) and other professionals (freelancers or university staff). Our research sheds light on the current practice of disclosing specific teaching and research interests or expertise in social media bio profiles for personal branding, especially among scholars. Unique communication contexts such as social media hashtag communities still bring challenges to the dissemination of information, relationship building, and personal branding strategies. Our results also provide recommendations for scholars (faculty and researchers), graduate students, university staff, and practitioners to improve communication practices and personal branding strategies on social media hashtag communities.

BackgroundControlling the COVID-19 outbreak in Brazil is a challenge due to the population’s size and urban density, inefficient maintenance of social distancing and testing strategies, and limited availability of testing resources. ObjectiveThe purpose of this study is to effectively prioritize patients who are symptomatic for testing to assist early COVID-19 detection in Brazil, addressing problems related to inefficient testing and control strategies. MethodsRaw data from 55,676 Brazilians were preprocessed, and the chi-square test was used to confirm the relevance of the following features: gender, health professional, fever, sore throat, dyspnea, olfactory disorders, cough, coryza, taste disorders, and headache. Classification models were implemented relying on preprocessed data sets; supervised learning; and the algorithms multilayer perceptron (MLP), gradient boosting machine (GBM), decision tree (DT), random forest (RF), extreme gradient boosting (XGBoost), k-nearest neighbors (KNN), support vector machine (SVM), and logistic regression (LR). The models’ performances were analyzed using 10-fold cross-validation, classification metrics, and the Friedman and Nemenyi statistical tests. The permutation feature importance method was applied for ranking the features used by the classification models with the highest performances. ResultsGender, fever, and dyspnea were among the highest-ranked features used by the classification models. The comparative analysis presents MLP, GBM, DT, RF, XGBoost, and SVM as the highest performance models with similar results. KNN and LR were outperformed by the other algorithms. Applying the easy interpretability as an additional comparison criterion, the DT was considered the most suitable model. ConclusionsThe DT classification model can effectively (with a mean accuracy≥89.12%) assist COVID-19 test prioritization in Brazil. The model can be applied to recommend the prioritizing of a patient who is symptomatic for COVID-19 testing.

Cette revue de littérature, majoritairement en anglais, sur les sciences citoyennes à l’ère numérique, montre que le libellé « science citoyenne » recouvre de multiples réalités et que le phénomène lui-même reste peu théorisé. La revue de littérature expose les définitions principales et discute les typologies disponibles dans la littérature pour étudier la participation des non-professionnels à la production de connaissances dans les sciences de la nature. Trois enjeux majeurs sont abordés : 1) les motivations des participants dans les projets de science citoyenne ; 2) l’expertise ; 3) la légitimité et la qualité des données. Le propos est illustré par des exemples tirés de travaux empiriques réalisés sur les « sciences citoyennes 2.0 », menés sur plusieurs années au sein de terrains de recherche dans les domaines de la botanique et de l’entomologie.

Online academic communities are valuable spaces where participants can share information, find and provide support, and even be entertained. Online academic communities refer to hashtag-specific chats or other forms of affinity groups. Although these communities have been researched in the literature, more studies are needed to understand the uses, gratifications, and strategies that shape a social media hashtag community for the academic community (e.g., faculty, graduate students, and university staff). This research explores how participants of social media hashtag communities such as #AcademicTwitter use strategic messaging and informal learning strategies. It also explores the uses and gratifications members receive for participating in these hashtag communities. X (formerly known as Twitter) data on #AcademicTwitter from 2021 were retrieved and analyzed using a content analysis. This study found that members mainly encouraged material support using visuals and links as message strategies. Findings provide an empirically tested framework of strategic messaging and informal learning strategies that participants used to motivate others to participate and gratify them to continue engaging.