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Background:Spinal cord injury (LM) above T6 is followed by a loss of supraspinal sympathetic control of the heart, disrupting autonomic balance and increasing cardiovascular risk.Objective: To evaluate cardiac autonomic modulation, biochemical markers, and sleep quality in wheelchair users with spinal cord injury and strength training.Methods:A 12-week cross-sectional study included 50 male participants aged between 20 and 52 years. With the evaluation of anthropometric measurements and body composition, Biochemical evaluation, Measurement of blood pressure, Pittsburgh Sleep Quality Index (PSQI), Injury Level, Assessment of the heart rate variability.Results:they point to a better HRV behavior in the wheelchair basketball (WCB) and wheelchair basketball + strength training (WCBS) groups to wheelchair control (WC). These data indicate that basketball practice and strength exercise combined with basketball practice can positively affect autonomic modulation.Conclusion:The practice of basketball, associated with resistance training, may improve hemodynamic, metabolic, and autonomic parameters.

A creatina é uma amina nitrogenada que sofre alterações à medida que o indivíduo envelhece, diminuindo assim seu suporte energético, tendo reflexo no dia-a-dia. O objetivo do estudo foi avaliar a influência da creatina na melhora da capacidade funcional de mulheres idosas. As participantes foram distribuídas em dois grupos. A ingestão da creatina foi realizada durante o período de 1 mês. Foram realizados medidas antropométricas, dosagem de creatinina e o testeTime Up and Go (TUG). Os dados foram analisados pelo Graphpad Prisma 5.0. O nível de significância foi de (p < 0,05). As alterações verificadas na dosagem de creatinina, no percentual de gordura, na circunferência abdominal, na massa muscular e no teste TUG dos dois grupos, não foram estatisticamente significantes. O estudo sugere que um controle alimentar e um maior tempo de intervenção com creatina, de acordo com protocolo, possibilitem resultados mais evidentes.&nbsp

Evaluate the cardiac autonomic modulation of adolescents with different levels of sleep quality. Methods: Adolescents aged 11 to 17 years who presented themselves an explanation of the project with consent form signed by participated in the study. Anthropometric and hemodynamic data collected, and questionnaires. Results: Analysis of the variables, age, systolic blood pressure, diastolic blood pressure, waist circumference, body fat and body mass index among the groups with good and poor sleep quality did not present a significant difference (p>0.05) in any paired characteristics. Time domain analysis indicated lower values in the vagal modulation with poor sleep quality. In the frequency domain, LF component increased and HF component decreased significantly in the group with poor sleep quality. There was also a statistical difference in the LF/ HF analysis, the group with poor sleep quality presented an increase in this variable. Conclusion: The subjects with poor sleep quality present lower cardiac autonomic modulation.

Made available in DSpace on 2022-04-28T19:51:26Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-01-01 This study aimed to evaluate the effect of vitamin D deficiency on sleep quality, depression, anxiety, and physiological stress in patients with chronic obstructive pulmonary disease (COPD). We screened for COPD patients with normal (NorVD) (n=24) and insufficient (InsVD) (n=7) vitamin D levels. The Pittsburgh sleep quality index (PSQI), the Beck anxiety inventory (BAI), the Beck depression inventory (BDI) and the Baevsky’s stress index were used for the sleep and psychometric evaluation. The evaluation of sleep quality by PSQI showed that NorVD individuals had higher duration and quality of sleep when compared with the InsVD group. Additionally, the group InsVD presented higher risk of developing sleep quality (OR=6.20; 95% CI=1.334, 29.013; p=0.009). BDI was higher in the InsVD, and this group had a higher risk of developing moderate and severe depression (OR=3.37; 95% CI=0.895, 12.722; p=0.03). The stress index indicated higher values in the InsVD in relation to the NorVD group (InsVD=24±0.8 vs. NorVD=16±0.9), and the group InsVD showed higher risk of developing high and very high physiological stress (OR=7.70; 95% CI=1.351, 43.878; p=0.01). The stress and sleep quality effects were negatively correlated with vitamin D levels. Insufficient levels of vitamin D negatively affect sleep quality and psychometric variables. Universidade Federal do Maranhão Departamento de Educação Física, MA Universidade Estadual de São Paulo Departamento de Farmácia, São Paulo Universidade Federal de São Paulo Departamento de Psicobiologia, São Paulo Universidade Federal do Maranhão Departamento de Medicina, MA Universidade Estadual de Campinas Departamento de Educação Física, São Paulo Universidade Estadual de São Paulo Departamento de Farmácia, São Paulo

Submitted by Daniella Santos (daniella.santos@ufma.br) on 2019-02-08T17:35:59Z No. of bitstreams: 1 CarlosDiasFilho.pdf: 1848381 bytes, checksum: 50cac3dc68235440b18cba4d3c1f0fb2 (MD5) Made available in DSpace on 2019-02-08T17:35:59Z (GMT). No. of bitstreams: 1 CarlosDiasFilho.pdf: 1848381 bytes, checksum: 50cac3dc68235440b18cba4d3c1f0fb2 (MD5) Previous issue date: 2018-10-16 CAPES Introduction: Systemic arterial hypertension is a chronic-degenerative disease with multifactorial origin and characterized by elevated and sustained levels of blood pressure (BP), increasing risk for cardiovascular diseases. Some environmental and genetic factors have a strong impact on the prevalence of this morbidity. Besides these factors, exist the autonomic imbalance. The autonomic imbalance is recognized as one of the main causes of systemic arterial hypertension. However, few studies have explored the impact of the presence of angiotensin converting enzyme gene polymorphism and family history of hypertension on autonomic dysfunction in adolescents. Aim: To analyze the autonomic modulation of adolescents with family history of hypertension and the participation of the angiotensin converting enzyme gene polymorphism. Materials and Methods: The sample consisted of 141 adolescents with mean ages of 14.89 ± 1,64 years, students of a public schools of São Luís, Maranhão. The students were divided in offspring of hypertensive parents group (OHP) and offspring normotensive parents group (ONP). Then, an electrocardiogram for posterior analysis of heart rate variability was performed, blood pressure collects, anthropometric measures, oral mucosal cells collect, and posteriorly genotyping and statistical analysis. Results: The main finding of this study was the reduction of vagal action in the OHP group in relation to the ONP group, both presenting the DD genotype. The results showed changes in the variables: Weight (kg): 52.07 ± 9.38 vs. 58.35 ± 10 , 53; BMI (kg / m²): 20.01 ± 2.76 vs. 22.34 ± 4.30; WC (cm): 67.44 ± 6.94 vs. 72.01 ± 8.18; HR (bpm): 78.90 ± 12.73 vs. 84.84 ± 9.99; Var RR (ms²): 2408 ± 212 vs. 1182 ± 819; | LF (ms²): 1463 ± 1448 Vs. 802 ± 851; LF (%): 43 ± 16 vs. 54 ± 16; HF (%): 57 ± 16 vs. 46 ± 16; RMSSD (ms): 51 ± 26 Vs. 40 ± 20 and SD1 (ms): 39 ± 21 vs. 29 ± 14. Differences were also found when compared only the groups FPH vs. FPN on the variables %fat (%): 23.60 ± 8.33 vs. 26.33 ± 7.08; SBP (mmHg): 109.22 ± 11.32 vs. 114.62 ± 11.49; HR (bpm): 78.92 ± 12.85 vs. 83.53 ± 12.30; LF (%): 43.63 ± 15.25 vs. 48.60 ± 17.14; HF (%): 57.36 ± 15.25. Significant differences were also found when divided FPH DD + DI vs. FPN DD + DI in BMI (kg / cm²): 20.30 ± 3.35 vs. 22.05 ± 4.23; SBP (mmHg): 109.52 ± 11.49 vs. 114.54 ± 11.35; LF (%): 43.66 ± 15.90 vs. 50.49 ± 17.38 and HF (%): 56.33 ± 15.90 vs. 49.47 ± 17.37. Conclusion: Adolescents with DD genotype and family history of arterial hypertension present minor cardiac autonomic modulation as a predictive factor of pathophysiological changes of the disease. Introdução: A hipertensão arterial sistêmica é uma doença crônico-degenerativa com origem multifatorial e características de níveis elevados e sustentados de pressão arterial (PA), aumentando risco para doenças cardiovasculares. Alguns fatores ambientais e genéticos exercem forte impacto sobre a prevalência desta doença. Além destes fatores, existe o desequilíbrio autonômico, reconhecido como um dos principais causadores da hipertensão arterial sistêmica. Entretanto poucos trabalhos têm estudado o impacto da presença do polimorfismo do gene da enzima conversora de angiotensina e história familiar de hipertensão na disfunção autonômica em adolescentes. Objetivo: Analisar a modulação autonômica de adolescentes com histórico familiar de hipertensão e a participação do polimorfismo do gene da enzima conversora da angiotensina. Materiais e Métodos: A amostra consistiu-se de 141 adolescentes entre 14,89 ± 1,64 anos de idade, estudantes de escolas públicas de São Luís, Maranhão. Que foram divididos em filhos de pais hipertensos (FPH) e filhos de pais normotensos (FPN). Em seguida foi feito o eletrocardiograma para posterior analise da variabilidade da frequência cardíaca, aferição da pressão arterial, medidas antropométricas, coleta das células orais, posteriormente a genotipagem da enzima conversora da angiotensina e análise estatística. Resultados: O principal achado deste estudo foi a diminuição da ação vagal no grupo FPH com o genótipo DD em relação ao grupo FPN com o genótipo DD, apresentando alterações nas variáveis Peso (Kg): 52,07 ± 9,38 vs. 58,35 ± 10,53; IMC (Kg/m²): 20,01 ± 2,76 vs. 22,34 ± 4,30; CC (cm): 67,44 ± 6,94 vs. 72,01 ± 8,18; FC (bpm): 78,90 ± 12,73 vs. 84,84 ± 9,99; Var RR(ms²): 2408±212 vs. 1182±819; |BF(ms²):1463±1448 vs. 802±851; BF(%):43±16 vs. 54±16; AF(%): 57±16 vs. 46±16; RMSSD (ms): 51±26 vs. 40±20; SD1(ms): 39±21 vs. 29±14. Também foi encontrado diferenças quando relacionados somente FPH vs. FPN, nas variáveis de % gordura (%): 23,60 ± 8,33 vs. 26,33 ± 7,08; PAS (mmHg): 109,22 ± 11,32 vs. 114,62 ± 11,49; FC (bpm): 78,92 ± 12,85 vs. 83,53 ± 12,30; BF (%): 43.63 ± 15.25 vs. 48.60 ± 17.14; AF(%): 57.36 ± 15.25. valores diferentes também foram encontrados quando divididos FPH DD+DI vs. FPN DD+DI em IMC (kg/cm²): 20,30 ± 3,35 vs. 22,05 ± 4,23; PAS (mmHg): 109,52 ± 11,49 vs. 114,54 ± 11,35; BF (%): 43,66 ± 15,90 vs. 50,49 ± 17,38; AF (%): 56,33 ± 15,90 vs. 49,47 ± 17,37. Conclusão: Os resultados mostram que os adolescentes com genótipo DD e histórico familiar de hipertensão arterial apresentam modulação autonômica menor como fator preditivo de alterações fisiopatológicas da hipertensão arterial.