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Recent efforts in the network function virtualization (NFV) field have targeted ameliorating end-to-end latency of service function chains (SFCs) using network function (NF) composition. NF composition breaks the NF into building blocks and decides the appropriate combination for these blocks. However, two issues remain in current NF composition methods: (1) In the sequential scope, the fine-grained function's block-level composition eliminates redundancy, but with the drawback of flexibility restriction. (2) In the vertical scope, complete NF parallelism adds overhead in packet copying and reordering. To reconcile this, here we present ParaGraph, a subgraph-level NF composition with delay-balanced parallelism. ParaGraph has three main components: an NF subgraph-extraction module that extrapolates right-grained core function subgraphs from NFs; an orchestrator that dynamically composes subgraphs with delay-balanced parallelism; and an infrastructure performing lightweight packet copying and merging. We implement a ParaGraph prototype based on Click and the Data Plane Development Kit (DPDK); extensive evaluations show that with minimum overhead, ParaGraph reaches line-speed packet processing and reduces latency by up to 55% compared to state-of-the-art methods.

OBJECTIVE: To investigate predictors of anticoagulation efficacy in deep venous thrombosis (DVT) by ultrasound elastography (UE). METHODS: The basic clinical, laboratory and ultrasound treatment data of fifty-eight patients with DVT were collected and analyzed. Then the results of ultrasound after 3-month anticoagulation treatment were compared among different groups. Multiple logistic regression analysis was used to identify independent risk factors that affected anticoagulation efficacy. The predictive efficacy of each independent risk factor was accessed by drawing operating characteristic (ROC) curves. RESULTS: According to the regression analysis, the elastic modulus (OR = 0.631, P = 0.001) and strain rate ratio (OR = 0.332, P = 0.006) were identified as independent risk factors for the effectiveness of anticoagulation therapy in patients with DVT. According to the ROC curves, elastic modulus and strain rate ratio could predict effective anticoagulation therapy for DVT, and the optimal threshold values were 22.10 kPa and 1.80 respectively. The corresponding AUC values were 0.879 and 0.854, with a sensitivity of 71.4% and 59.5%, a specificity of 93.7%, and a Youden index of 65.1% and 62.7%, respectively. CONCLUSIONS: The elastic modulus (≤22.10 kPa) or strain rate ratio (≤1.80) of the thrombus were independent predictors for the effectiveness of anticoagulation therapy. [ABSTRACT FROM AUTHOR]