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International audience; Mycobacterium leprae was detected by optical microscopy, fluorescent in situ hybridization, and molecular detection in feces collected for the diagnosis of Entamoeba coli enteritis in a leprosy patient in Burkina Faso. This observation raises questions about the role of fecal excretion of M. leprae in the natural history and diagnosis of leprosy.

To determine the prevalence and risk factors for latent tuberculosis infection (LTBI) among three high-risk groups - household contacts of TB index cases, healthcare workers and slaughterhouse workers - in Bobo-Dioulasso, Burkina Faso.Participants were recruited to this cross-sectional study from March to July 2020 after giving informed consent. Sociodemographic, clinical and biological data were collected using a structured questionnaire. The QuantiFERON-TB Gold Plus test (QFT-Plus) and the tuberculin skin test (TST) were used for detection of LTBI. Bivariate and multivariate logistic regression analyses were performed to identify risk factors for LTBI.The prevalence of LTBI among 101 participants (age range 15-68 years) was 67.33% [95% confidence interval (CI) 57.27-76.33] and 84.16% (95% CI 75.55-90.66) based on QFT-Plus and TST results, respectively. Compared with healthcare workers and household contacts of TB index cases, the prevalence of LTBI among slaughterhouse workers was significantly higher for both QTF-Plus (96.8%;The prevalence of LTBI was high in all three groups, particularly slaughterhouse workers. The risk factors identified could form the basis of targeted intervention.

Objectives: To determine the prevalence and risk factors for latent tuberculosis infection (LTBI) among three high-risk groups - household contacts of TB index cases, healthcare workers and slaughterhouse workers - in Bobo-Dioulasso, Burkina Faso. Methods: Participants were recruited to this cross-sectional study from March to July 2020 after giving informed consent. Sociodemographic, clinical and biological data were collected using a structured questionnaire. The QuantiFERON-TB Gold Plus test (QFT-Plus) and the tuberculin skin test (TST) were used for detection of LTBI. Bivariate and multivariate logistic regression analyses were performed to identify risk factors for LTBI. Results: The prevalence of LTBI among 101 participants (age range 15-68 years) was 67.33% [95% confidence interval (CI) 57.27-76.33] and 84.16% (95% CI 75.55-90.66) based on QFT-Plus and TST results, respectively. Compared with healthcare workers and household contacts of TB index cases, the prevalence of LTBI among slaughterhouse workers was significantly higher for both QTF-Plus (96.8%; P /=15 years of exposure (AOR 5.617, 95% CI 1.202-32.198), having an animal at home (AOR 2.735, 95% CI 1.102-6.789) and protozoal infection (AOR 2.591, 95% CI 1.034-6.491) were significantly associated with LTBI on the QFT-Plus assay. Conclusion: The prevalence of LTBI was high in all three groups, particularly slaughterhouse workers. The risk factors identified could form the basis of targeted intervention.

INTRODUCTION: campylobacteriosis is zoonotic and one of the leading causes of bacterial foodborne diarrheal disease worldwide. Data on Campylobacter is scarce in Burkina Faso and do not provide information on the growing anti-microbial resistance (AMR) in the poultry value-chain. This study aims to assess the prevalence of Campylobacter spp simultaneously in poultry, in farmers and soil, as well as its impact on the emergence of AMR. METHODS: qualitative survey data provided information on the antibiotics used as breeding promoters in poultry farming. Campylobacter spp. strains were obtained from cloacal swabs, farmers´ stools and soil samples. Isolation indentification and drug sensitivity tests were performed in the bacteriology laboratory of the Centre Muraz using the automated Vitek 2 ID/AST, Biomerieux and Kirby Bauer method. RESULTS: the antibiotics used by farmers included: oxytetracycline, sulfadimidine, colistine, trimazin, erythromycin, streptomycin and colistin. The prevalence of campylobacter in poultry cloacal swabs was 4.44% (95% CI 1.4%, 7.5%). No campylobacter was isolated from human stools and soil samples. Three different species were isolated: Campylobacter jejuni (62.5%), Campylobacter fetus (25%) and Campylobacter coli (12.5%). From these species 37.5% were found to be resistant to ciprofloxacin and nalidixic acid, 50% to ampicillin and 87.5% to tetracycline. CONCLUSION: while the resistance of campylobacter to antibiotics relevant to public health was considerable, the overall antibiotic resistance was lower than expected considering the generous use of antimicrobials in poultry breeding.