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2024 MAY 11 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Current study results on type 2 diabetes have been published. According to [...]

Practice recommendations * Use fishing line cut to different lengths (4 cm = 10 g; 8 cm = 1 g) as substitutes for monofilaments to assist in the diagnosis of [...]

The diabetic neuropathies are heterogeneous, affecting different parts of the nervous system that present with diverse clinical manifestations. They may be focal or diffuse. Most common among the neuropathies are [...]

OBJECTIVE -- To evaluate the discriminative power of the Diabetic Neuropathy Symptom (DNS) and Diabetic Neuropathy Examination (DNE) scores for diagnosing diabetic polyneuropathy (PNP), as well as their relation with [...]

OBJECTIVE--Pupillary autonomic neuropathy is considered an early sign of the development of systemic autonomic neuropathy. Sympathetic denervation is related to the duration of diabetes and the development of systemic autonomic [...]

KEY WORDS * Lower limb screening * GP mini-clinic * Service review * Time management Introduction Opinion varies on which is the best setting for the delivery of lower limb [...]

The utility of standard cardiovascular tests for diagnosis of cardiac autonomic neuropathy in diabetes has been well documented. Attention must be paid to standardizing the procedure with regard to time [...]

The peripheral nerve disorders associated with diabetes are complex and probably involve a variety of causative mechanisms. This may give rise to difficulty in the classification of individual cases. A [...]

Uncle Sam wants you to keep your feet. To help you, the Health Resources and Services Administration (HRSA), part of the U.S. Department of Health and Human Services, has launched [...]

The devastating complications of diabetes are everyday realities for millions of patients, and foot problems are at or near the top of the list. With careful assessment and non-invasive testing, [...]

The autonomic nervous system controls cardiac function mainly through reflex modulation of heart-rate cyclic variations. The most prominent of these is sinus arrythmia, which is parasympathetic dependent. However, slower heart-rate [...], Power spectral analysis (PSA) of heart-rate variations has recently proved a useful tool in evaluating cardiovascular autonomic activity. It offers the possibility of examining both the functioning of parasympathetic and sympathetic pathways through breakdown into two frequency bands, and of their effects on heart-rate cyclic variability. We applied an autoregressive model for PSA study overall autonomic tone in 20 male age-matched control subjects and 53 insulin-dependent (type I) diabetic subjects, subdivided into three groups of 20, 15, and 18, each group presenting different degrees of autonomic involvement. We found that: 1) power spectrum density (PSD) values at high-frequency bands (parasympathetic dependent) were similar in diabetic subjects without cardiac autonomic neuropathy (CAN) and in control subjects, but differed significantly from diabetic subjects with mild CAN and severe CAN, both standing and lying; 2) PSD values at low frequency (mainly sympathetic dependent) were similar, or slightly different, in diabetic subjects without CAN and in control subjects, but differed significantly from diabetic subjects with mild and severe CAN, both standing and lying; 3) as an expression of parasympathetic versus sympathetic coherence, correlations, both standing and lying, existed between PSD values at low- and high-frequency bands in control and diabetic subjects without CAN, but not in diabetic subjects with CAN; and 4) different degrees of correlation characterized the PSD values of high and low frequencies versus traditional cardiovascular test values in the diabetic subjects. The best correlation was between PSD low-frequency values and the lying-to-standing maneuver. These data indicate that PSA 1) can discriminate between differing degrees of parasympathetic involvement, 2) can discriminate between different degrees of sympathetic involvement, and 3) offers a picture of overall autonomic activity that can be explored only partially by traditional cardiovascular autonomic tests and 4) can reveal parasympathetic versus sympathetic dyssynergia. These data suggest that cardiovascular autonomic test may reflect different aspects of autonomic pathways. Hence, PSA appears to be a powerful tool in the determination of autonomic tone in diabetic CAN. Diabetes 41:633-40, 1992

Table of Contents Abstract Introduction Materials and Methods Results Discussion Conclusion References Abstract Oxidative stress resulting from enhanced free-radical formation and/or a defect in antioxidant defenses has been implicated in [...]

Clinical Briefs By Louis Kuritzky, MD, Clinical Assistant Professor, University of Florida, Gainesville. Dr. Kuritzky is a consultant for GlaxoSmithKline and is on the speaker's bureau of GlaxoSmithKline, 3M, Wyeth-Ayerst, [...]

Table of Contents Abstract Introduction Material And Methods Results Discussion References Abstract Fiber Density (FD) and Macro motor unit potential (macro-MUP) amplitude measurements have a higher sensitivity in detecting diabetic [...]

Abstract Fiber Density (FD) and Macro motor unit potential (macro-MUP) amplitude measurements have a higher sensitivity in detecting diabetic neuropathy as compared to nerve conduction studies (NCS). The the aim [...]

Diabetic symmetrical distal neuropathy or diabetic polyneuropathy is the most common form of diabetic neuropathy and a leading cause of neuropathy in the United States. Complications include pain, loss of ambulation, and risk for amputation. Recognizing the typical pattern of presentation and risk factors for diabetic polyneuropathy is essential for making the correct diagnosis and determining appropriate workup and need for neurologic consultation. Intensive glucose control is the only therapy proven to prevent or slow the progression of diabetic polyneuropathy. Supportive therapies, including pain management and podiatric care, can improve quality of life and prevent chronic ulcerations. Poncelet AN. Diabetic polyneuropathy: Risk factors, patterns of presentation, diagnosis, and treatment. Geriatrics 2003; 58(June)16-30. Key words: neuropathy * diabetes mellitus * pain management, Diabetes mellitus is one of the most common causes of neuropathy. (1) Diabetic polyneuropathy results in significant disability and morbidity including severe pain, loss of ambulation, and an increased risk [...]

JEANET GERRITSEN,[1] JACQUELINE M. DEKKER,[2] BEN J. TENVOORDE, [1] PIET J. KOSTENSE, [3] ROBERT J. HEINE, [2] LEX M. BOUTER, [2] ROB M. HEETHAAR, [1] COEN D.A. STEHOUWER, [2] The [...]

Sharpen Your Diagnostic Skills HISTORY A 54-year-old attorney is seen on admission to nursing home's rehabilitation unit after amputation of 2 toes and plastic-surgical repair of a third toe. Had [...]