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1. Safety Design Approach for Structural Batteries Integration in Composite Structures by Means of Multiphysics Analysis

Author

Di Mauro, G., Guida, M., Gomez, L. M., Olivares, G., Chaari, Fakher, Series Editor, Gherardini, Francesco, Series Editor, Ivanov, Vitalii, Series Editor, Haddar, Mohamed, Series Editor, Cavas-Martínez, Francisco, Editorial Board Member, di Mare, Francesca, Editorial Board Member, Kwon, Young W., Editorial Board Member, Tolio, Tullio A. M., Editorial Board Member, Trojanowska, Justyna, Editorial Board Member, Schmitt, Robert, Editorial Board Member, Xu, Jinyang, Editorial Board Member, Lopresto, Valentina, editor, and Papa, Ilaria, editor

Published
2025
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7. Contrast media-induced nephropathy: how has Italy contributed in the past 30 years? A systematic review

Author

Sessa M, Rossi C, Mascolo A, Scavone C, di Mauro G, Grassi R, Sportiello L, Cappabianca S, and Rafaniello C

Subjects
nephropathy, contrast media, Italy, systematic review., Therapeutics. Pharmacology, RM1-950
Abstract

Maurizio Sessa,1,* Claudia Rossi,2,* Annamaria Mascolo,1 Cristina Scavone,1 Gabriella di Mauro,1 Roberto Grassi,2 Liberata Sportiello,1 Salvatore Cappabianca,2 Concetta Rafaniello1 1Section of Pharmacology “L Donatelli”, Department of Experimental Medicine, University of Campania “L Vanvitelli”, Naples, Italy; 2Section of Radiology and Radiotherapy, Department of Clinical and Experimental Medicine “Magrassi-Lanzara”, University of Campania “L Vanvitelli”, Naples, Italy *These authors contributed equally to this work Background and objective: The use of contrast media in Italy has exponentially increased in the past 3 decades. However, it is unknown whether there has been an increase in clinical research evaluating the risks associated with contrast media usage, especially regarding contrast-induced nephropathy. To fill this gap in knowledge, we performed a systematic review.Study eligibility criteria: Meta-analyses, observational studies, and clinical trials assessing contrast media-induced nephropathy as the safety outcome, in which at least one author was affiliated with an Italian university/health care structure, were eligble.Data sources: Ovid MEDLINE, Ovid Embase, Cochrane Methodology Register, and Web of Science were screened.Participants: Men and women exposed to contrast media.Results: In total, 60 original articles were retrieved with an incremental trend between 1990 and 2017. Cohort studies were the most common study design represented. In total, 45 of 60 (75.0%) studies were monocenter studies and 41 of 60 (68.3%) received no funding. In all, 91.7% of studies disclosed no conflicts of interest and 81.7% had no external collaboration. Most of the studies provided a level of evidence of III-2 (32/60; 53.3%) and II (23/60; 38.3%). In total, 50 of 60 studies (83.3%) were published in a scientific journal ranked in the first quartile of their subject area.Conclusion: There was an increased number of studies evaluating contrast-induced nephropathy in Italy during the last three decades. These studies covered procedures to prevent contrast-induced nephropathy or aimed to identify risk factors, biomarkers, and scores, and their related prognosis. Keywords: nephropathy, contrast media, Italy, systematic review, drug safety, adverse drug reaction, pharmacovigilance, post-marketing surveillance

Published
2017

8. Recommendations on Complementary Feeding as a Tool for Prevention of Non-Communicable Diseases (NCDs)—Paper Co-Drafted by the SIPPS, FIMP, SIDOHaD, and SINUPE Joint Working Group

Author

Caroli, M, Vania, A, Verga, M, Di Mauro, G, Bergamini, M, Cuomo, B, D'Anna, R, D'Antonio, G, Iacono, I, Dessi, A, Doria, M, Fanos, V, Fiore, M, Francavilla, R, Genovesi, S, Giussani, M, Gritti, A, Iafusco, D, Leonardi, L, Miniello, V, Del Giudice, E, Palma, F, Pastore, F, Scotese, I, Simeone, G, Squicciarini, M, Tezza, G, Troiano, E, Umano, G, Caroli M., Vania A., Verga M. C., Di Mauro G., Bergamini M., Cuomo B., D'anna R., D'antonio G., Iacono I. D., Dessi A., Doria M., Fanos V., Fiore M., Francavilla R., Genovesi S., Giussani M., Gritti A., Iafusco D., Leonardi L., Miniello V. L., Del Giudice E. M., Palma F., Pastore F., Scotese I., Simeone G., Squicciarini M., Tezza G., Troiano E., Umano G. R., Caroli, M, Vania, A, Verga, M, Di Mauro, G, Bergamini, M, Cuomo, B, D'Anna, R, D'Antonio, G, Iacono, I, Dessi, A, Doria, M, Fanos, V, Fiore, M, Francavilla, R, Genovesi, S, Giussani, M, Gritti, A, Iafusco, D, Leonardi, L, Miniello, V, Del Giudice, E, Palma, F, Pastore, F, Scotese, I, Simeone, G, Squicciarini, M, Tezza, G, Troiano, E, Umano, G, Caroli M., Vania A., Verga M. C., Di Mauro G., Bergamini M., Cuomo B., D'anna R., D'antonio G., Iacono I. D., Dessi A., Doria M., Fanos V., Fiore M., Francavilla R., Genovesi S., Giussani M., Gritti A., Iafusco D., Leonardi L., Miniello V. L., Del Giudice E. M., Palma F., Pastore F., Scotese I., Simeone G., Squicciarini M., Tezza G., Troiano E., and Umano G. R.

Abstract

Adequate and balanced nutrition is essential to promote optimal child growth and a long and healthy life. After breastfeeding, the second step is the introduction of complementary feeding (CF), a process that typically covers the period from 6 to 24 months of age. This process is, however, still highly controversial, as it is heavily influenced by socio-cultural choices, as well as by the availability of specific local foods, by family traditions, and pediatrician beliefs. The Società Italiana di Pediatria Preventiva e Sociale (SIPPS) together with the Federazione Italiana Medici Pediatri (FIMP), the Società Italiana per lo Sviluppo e le Origine della Salute e delle Malattie (SIDOHaD), and the Società Italiana di Nutrizione Pediatrica (SINUPE) have developed evidence-based recommendations for CF, given the importance of nutrition in the first 1000 days of life in influencing even long-term health outcomes. This paper includes 38 recommendations, all of them strictly evidence-based and overall addressed to developed countries. The recommendations in question cover several top-ics such as the appropriate age for the introduction of CF, the most appropriate quantitative and qualitative modalities to be chosen, and the relationship between CF and the development of Non-Communicable Diseases (NCDs) later in life.

Published
2022

9. MICRORNA-197-3P UP-REGULATION IN SERA AND CELLS FROM MALIGNANT PLEURAL MESOTHELIOMA AFFECTED PATIENTS

Author

BONONI, I., primary, TOGNON, M., additional, DI MAURO, G., additional, FRONTINI, F., additional, OTON-GONZALEZ, L., additional, TORREGGIANI, E., additional, IAQUINTA, M.R., additional, MAZZIOTTA, C., additional, MAZZONI, E., additional, STENDARDO, M.R., additional, BOSCHETTO, P., additional, LIBENER, R., additional, GUASCHINO, R., additional, GROSSO, F., additional, and MARTINI, F., additional

Published
2022
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10. Inter-society consensus for the use of inhaled corticosteroids in infants, children and adolescents with airway diseases (vol 47, pg 1, 2021)

Author

Duse, M, Santamaria, F, Verga, M, Bergamini, M, Simeone, G, Leonardi, L, Tezza, G, Bianchi, A, Capuano, A, Cardinale, F, Cerimoniale, G, Landi, M, Malventano, M, Tosca, M, Varricchio, A, Zicari, A, Alfaro, C, Barberi, S, Becherucci, P, Bernardini, R, Biasci, P, Caffarelli, C, Caldarelli, V, Capristo, C, Castronuovo, S, Chiappini, E, Cutrera, R, De Castro, G, De Franciscis, L, Decimo, F, Iacono, I, Diaferio, L, Di Cicco, M, Di Mauro, C, Di Mauro, D, Di Mauro, F, Di Mauro, G, Doria, M, Falsaperla, R, Ferraro, V, Fanos, V, Galli, E, Ghiglioni, D, Indinnimeo, L, Kantar, A, Lamborghini, A, Licari, A, Lubrano, R, Luciani, S, Macri, F, Marseglia, G, Martelli, A, Masini, L, Midulla, F, Minasi, D, Miniello, V, Del Giudice, M, Morandini, S, Nardini, G, Nocerino, A, Novembre, E, Pajno, G, Paravati, F, Piacentini, G, Piersantelli, C, Pozzobon, G, Ricci, G, Spanevello, V, Turra, R, Zanconato, S, Borrelli, M, Villani, A, Corsello, G, and Peroni, D

Subjects
Settore MED/38
Published
2022

11. Tendency to worry and fear of mental health during Italy’s COVID-19 lockdown

Author

Baiano C., Zappullo I., Conson M., Di Mauro G., Petra M., Piacenti M., Rauso B., Baiano, C., Zappullo, I., Conson, M., Di Mauro, G., Petra, M., Piacenti, M., and Rauso, B.

Subjects
Male, Mindfulness, mindfulness, Psychometrics, Health, Toxicology and Mutagenesis, Psychological intervention, lcsh:Medicine, Anxiety, 0302 clinical medicine, Surveys and Questionnaires, Surveys and Questionnaire, 030212 general & internal medicine, media_common, Fear, Mental Health, Italy, Worry, Quarantine, Female, medicine.symptom, Psychology, Coronavirus Infections, Psychometric, Clinical psychology, Human, Adult, media_common.quotation_subject, Pneumonia, Viral, Affect (psychology), Article, 03 medical and health sciences, Betacoronavirus, Young Adult, Mindfulne, medicine, Humans, Pandemics, Threat, Betacoronaviru, Pandemic, SARS-CoV-2, Coronavirus Infection, lcsh:R, Public Health, Environmental and Occupational Health, COVID-19, Mental health, Anxiety sensitivity, Self Report, 030217 neurology & neurosurgery
Abstract

Background: We tested whether the tendency to worry could affect psychological responses to quarantine by capitalizing on the opportunity of having collected data before the COVID-19 outbreak on measures of worry, anxiety, and trait mindfulness in a group of university students. Methods: Twenty-five participants completed self-report measures assessing worry (Penn State Worry Questionnaire, PSWQ), anxiety (Anxiety Sensitivity Index, ASI-3), and trait mindfulness (Mindful Attention Awareness Scale, MAAS) at T0 (pre-lockdown, 4 November 2019&ndash, 17 February 2020) and T1 (at the end of lockdown, 26 April&ndash, 30 April 2020). We compared assessments at the two time points in the whole sample and in high and low worriers (defined at T0 by scores on PSWQ respectively above and below 1.5 SD from mean of the Italian normative sample). Outcomes: High worriers showed at T1 a significant increase of anxiety sensitivity and fear of mental health in comparison to low worriers. Moreover, in the whole sample, at T1 trait mindfulness was inversely related to worry and fear of mental health. Interpretation: A valuable approach to support individuals experiencing anxiety related to the COVID-19 outbreak could be represented by mindfulness-based interventions improving the ability to focus attention and awareness on the present moment.

Published
2020

12. ICG fluorescence imaging in colorectal surgery: a snapshot from the ICRAL study group

Author

Baiocchi, G. L., Guercioni, G., Vettoretto, N., Scabini, S., Millo, P., Muratore, A., Clementi, Maria Elisabetta, Sica, G., Delrio, P., Longo, G., Anania, G., Barbieri, Pietro Vittorio, Amodio, P., Di Marco, C., Baldazzi, G., Garulli, G., Patriti, A., Pirozzi, F., De Luca, R., Mancini, S., Pedrazzani, C., Scaramuzzi, M., Scatizzi, M., Taglietti, L., Motter, M., Ceccarelli, G., Totis, M., Gennai, A., Frazzini, D., Di Mauro, G., Capolupo, G. T., Crafa, F., Marini, P., Ruffo, G., Persiani, Roberto, Borghi, F., de Manzini, N., Catarci, Marco, Clementi M., Barbieri V., Persiani R. (ORCID:0000-0002-1537-5097), Catarci M., Baiocchi, G. L., Guercioni, G., Vettoretto, N., Scabini, S., Millo, P., Muratore, A., Clementi, Maria Elisabetta, Sica, G., Delrio, P., Longo, G., Anania, G., Barbieri, Pietro Vittorio, Amodio, P., Di Marco, C., Baldazzi, G., Garulli, G., Patriti, A., Pirozzi, F., De Luca, R., Mancini, S., Pedrazzani, C., Scaramuzzi, M., Scatizzi, M., Taglietti, L., Motter, M., Ceccarelli, G., Totis, M., Gennai, A., Frazzini, D., Di Mauro, G., Capolupo, G. T., Crafa, F., Marini, P., Ruffo, G., Persiani, Roberto, Borghi, F., de Manzini, N., Catarci, Marco, Clementi M., Barbieri V., Persiani R. (ORCID:0000-0002-1537-5097), and Catarci M.

Abstract

Background: Fluorescence-guided visualization is a recently proposed technology in colorectal surgery. Possible uses include evaluating perfusion, navigating lymph nodes and searching for hepatic metastases and peritoneal spread. Despite the absence of high-level evidence, this technique has gained considerable popularity among colorectal surgeons due to its significant reliability, safety, ease of use and relatively low cost. However, the actual use of this technique in daily clinical practice has not been reported to date. Methods: This survey was conducted on April 2020 among 44 centers dealing with colorectal diseases and participating in the Italian ColoRectal Anastomotic Leakage (iCral) study group. Surgeons were approximately equally divided based on geographical criteria from multiple Italian regions, with a large proportion based in public (89.1%) and nonacademic (75.7%) centers. They were invited to answer an online survey to snapshot their current behaviors regarding the use of fluorescence-guided visualization in colorectal surgery. Questions regarding technological availability, indications and techniques, personal approaches and feelings were collected in a 23-item questionnaire. Results: Questionnaire replies were received from 37 institutions and partially answered by 8, as this latter group of centers do not implement fluorescence technology (21.6%). Out of the remaining 29 centers (78,4%), fluorescence is utilized in all laparoscopic colorectal resections by 72.4% of surgeons and only for selected cases by the remaining 27.6%, while 62.1% of respondents do not use fluorescence in open surgery (unless the perfusion is macroscopically uncertain with the naked eye, in which case 41.4% of them do). The survey also suggests that there is no agreement on dilution, dosing and timing, as many different practices are adopted based on personal judgment. Only approximately half of the surgeons reported a reduced leak rate with fluorescence perfusion assessmen

Published
2021

14. Adverse drug reactions and gender differences: What changes in drug safety?

Author

Di Mauro G., Zinzi A., Vitiello F., Restaino M., Sportiello L., Rafaniello C., Sullo M. G., Capuano A., Di Mauro, G., Zinzi, A., Vitiello, F., Restaino, M., Sportiello, L., Rafaniello, C., Sullo, M. G., and Capuano, A.

Subjects
Safety profile, Adverse drug reaction, Gender difference, Phar-macovigilance
Abstract

Gender differences are influenced by cultural, social, psychological and biological factors. A specific area of medicine has been identified to understand the mechanisms underlying gender differences affecting health status, the course of a disease and pharmacological therapy out-comes. The main gender-related variables affecting drug response are weight, body surface area, height, fat mass, plasma volume and total body water. Gender differences can also influence the drug safety profile; indeed, real-world epidemiological data show a greater incidence and severity of adverse drug reactions in women than in men. Because of several biases in conducting pre-marketing gender-spe-cific studies, post-marketing studies are needed in order to evaluate gender differences in terms of drug efficacy and safety. Therefore, the aim of this review is to provide further evidence in order to show the incidence of specific gender-related adverse drug reactions (ADRs). In this context, we analyzed ADRs reported across the 2001-2018 period in the spontaneous reporting system in the Campania Region (It-aly), in terms of number and severity. In line with literature data, our results showed a higher number of reports involv-ing women than men, especially in those aged 18-64 years. Similarly, severe ADRs were more frequently reported in women. Therefore, an implementation of gender-specific pharmacovigilance activities would allow a further better characterization of the safety profile of drugs used in clinical practice.

Published
2019

21. Indagine SiPPS sulle opinioni dei pediatri sulle vaccinazioni

Author

Pinto, L., Liguori, R., Basilicata, A., Bon, A., Carbone, M., Di Mauro, C., Falco, P., Aniello, F., Muccio, C., Picozzi, F., Pullano, F., Schiavone Giacco, G., Spagnuolo, M., Sticco, M., Mariniello, A., Di Mauro, G., VECCHIO, Davide, Pinto, L., Liguori, R., Basilicata, A., Bon, A., Carbone, M., Di Mauro, C., Falco, P., Aniello, F., Muccio, C., Picozzi, F., Pullano, F., Schiavone Giacco, G., Spagnuolo, M., Sticco, M., Vecchio, D., Mariniello, A., and Di Mauro, G.

Subjects
Settore MED/38 - Pediatria Generale E Specialistica, Vaccinazioni, salute globale, pediatria
Published
2015

22. Guidelines for the diagnosis and treatment of acute and subacute rhinosinusitis in children

Author

Esposito S, Principi N, Di Pietro P, Bona G, Longhi R, Navone C, De Luca G, Michelozzi C, Miniello V, Morelli M, Tel F, Traverso A, Tremolati E, de Martino M, Bosis S, Chiappini E, Galli L, Tovo P, Paravati F, Plebani A, Vierucci A, Barbato A, Marseglia G, Baldi F, Barberi S, Bellasio M, Boner A, Cuffari A, Decimo F, De Rosa M, Leo G, del Giudice MM, Piacentini G, Tripodi S, Di Mauro G, Brusoni G, Zuccotti GV, Passali D, Serra A, Pagnataro L, Belussi L, Marchisio P, Eandi M, Novelli A, Scaglione F, Nicoletti G, Speciale A.M. Pediatrics, Italian Society of Otorhinolaryngology, Italian Society of Chemotherapy, Italian Society of Microbiology, LONGO, GIORGIO, Esposito, S, Principi, N, DI PIETRO, P, Bona, G, Longhi, R, Navone, C, DE LUCA, G, Michelozzi, C, Miniello, V, Morelli, M, Tel, F, Traverso, A, Tremolati, E, DE MARTINO, M, Bosis, S, Chiappini, E, Galli, L, Tovo, P, Paravati, F, Plebani, A, Vierucci, A, Barbato, A, Marseglia, G, Baldi, F, Barberi, S, Bellasio, M, Boner, A, Cuffari, A, Decimo, Fabio, DE ROSA, M, Leo, G, Longo, G, MIRAGLIA DEL GIUDICE, Michele, Piacentini, G, Tripodi, S, DI MAURO, G, Brusoni, G, Zuccotti, Gv, Passali, D, Serra, A, Pagnataro, L, Belussi, L, Marchisio, P, Eandi, M, Novelli, A, Scaglione, F, Nicoletti, Giovanni Francesco, Speciale, Am, Di Pietro, P, De Luca, G, de Martino, M, Decimo, F, De Rosa, M, Longo, Giorgio, del Giudice, Mm, Di Mauro, G, Nicoletti, G, Pediatrics, Speciale A. M., Italian Society of, Otorhinolaryngology, Italian Society of, Chemotherapy, and Italian Society of, Microbiology

Subjects
medicine.medical_specialty, sinusitis, respiratory tract infection, Respiratory System Agents, MEDLINE, subacute rhinosinusiti, English language, Guidelines, Drug Administration Schedule, subacute rhinosinusitis, children, Terminology as Topic, medicine, Acute rhinosinusitis, Humans, Pharmacology (medical), rhinosinusitis, guidelines, Child, Sinusitis, Intensive care medicine, Rhinitis, Pharmacology, Settore MED/38 - Pediatria Generale e Specialistica, Human studies, business.industry, medicine.disease, Antibiotic treatment, Anti-Bacterial Agents, Surgery, Infectious Diseases, Oncology, El Niño, Settore BIO/14 - Farmacologia, business
Abstract

The importance of rhinosinusitis finally reached pediatricians' attention a few years ago, and it has now been demonstrated that it is medically important and has a considerable socioeconomic impact in childhood. These guidelines, which have been prepared with and approved by many Italian Scientific Societies, are based on the most recent findings in the fields of clinical symptoms, imaging and microbiology tests for the diagnosis of acute rhinosinusitis, and efficacy evidence concerning antibiotic treatment and non-antibiotic adjuvant treatment. A Pubmed search using the key words "sinusitis", "rhinosinusitis", "child" and "antibiotic treatment", and the limits "human studies" and "English language", led to the selection of more than 2,700 articles published between 1966 and 2007. These guidelines are based on the 125 that were considered truly relevant and reflect the most widely shared positions concerning the diagnosis and treatment of acute, subacute and recurrent rhinosinusitis in children.

Published
2008

23. I disturbi del sonno: il Progetto 'Ci piace sognare'

Author

Brambilla, P, Barberi, S, Bernasconi, S, Bona, G, Brusoni, G, Buongiovanni, C, Carotenuto, M, Chiappini, E, Di Mauro, G, Ghiglioni, D, Gnecchi, M, Giussani, M, Iughetti, Lorenzo, Maffeis, C, Miraglia Del Giudice, E, Pasinato, A, Picca, M, Privitera, F, Sticco, M, Tamassia, G, Venturelli, L, Verduci, E, Villella, A., Brambilla, P, Barberi, S, Bernasconi, S, Bona, G, Brusoni, G, Buongiovanni, C, Carotenuto, Marco, Chiappini, E, Di Mauro, G, Ghiglioni, D, Gnecchi, M, Giussani, M, Iughetti, L, Maffeis, C, MIRAGLIA DEL GIUDICE, Emanuele, Pasinato, A, Picca, M, Privitera, F, Sticco, M, Tamassia, G, Venturelli, L, Verduci, E, and Villella, A.

Subjects
sonno
Published
2014

24. Recommendations for pediatric tuberculosis vaccination in Italy

Author

Montagnani, C, Esposito, S, Galli, L, Chiappini, E, Principi, N, de Martino, M, Bosis, S, Tagliabue, C, Senatore, L, Ascolese, B, Villani, A, Lancella, L, Cursi, L, Grandin, A, Marabotto, C, Ciofi, D, Festini, F, Anziati, M, Becciani, S, Remaschi, G, Sollai, S, Tersigni, C, Venturini, E, Guarino, A, Lo Vecchio, A, Scotto, R, Gabiano, C, Garazzino, S, Le Serre, D, Raffaldi, I, Bernardi, F, Bertazzoni, E, Blasi, F, Bocchino, M, Assante, L, Castagnola, E, Losurdo, G, Codecasa, L, Di Mauro, G, Faccini, M, Marseglia, G, Mascolo, A, Di Comite, A, Stronati, M, Matteelli, A, Migliori, Gb, D’Ambrosio, L, Centis, R, Pasinato, Cirillo, Tortoli, Russo, Scaglione, F, Scala, E, and Tomà, P

Subjects
Pediatrics, medicine.medical_specialty, Tuberculosis, Immunology, Breastfeeding, Tuberculin, Reviews, Disease, Tuberculous meningitis, 03 medical and health sciences, 0302 clinical medicine, children, prevention, BCG, tuberculosis, vaccination, vaccine, 030225 pediatrics, medicine, Immunology and Allergy, Humans, 030212 general & internal medicine, Immunization Schedule, Pharmacology, business.industry, medicine.disease, Settore MED/38, Pediatric tuberculosis, Vaccination, Italy, BCG Vaccine, business, BCG vaccine
Abstract

Bacillus Calmette-Guerin (BCG) vaccine is still the only vaccine approved for the prevention of tuberculosis (TB), and is widely used in highly endemic countries, where all newborns receive a single intradermal dose immediately after birth; however, the recommendations concerning its use in Europe vary widely from country to country. This document describes the recommendations of a group of Italian scientific societies concerning its pediatric use in Italy, the persistence of the protection it provides, its safety, its interference with tuberculin skin test (TST) responses, and the children who should be vaccinated. The experts conclude that BCG vaccination provides a good level of protection against tuberculous meningitis and disseminated forms, and a fair level of protection against pulmonary disease; the protective effective lasts at least 10 years, and revaccination offers no advantages over a single administration. The vaccine is safe in immunocompetent subjects, and affects the response to a TST for at least 6 y On the basis of these observations, we recommend its use in Italy in all TST-negative immunocompetent newborns and breastfeeding infants aged

Published
2015

27. Le immagini del Turismo Relazionale Integrato in Sicilia

Author

BINI, Giada, Battaglia, A, Trapassi, A, Giunta, M, Di Mauro, G, Marchese, S., Gulotta, D, Naselli, F, Trapani, F, Bini, G, Battaglia, A, Trapassi, A, Giunta, M, Di Mauro, G, and Marchese, S

Subjects
turismo relazionale integrato, Settore ICAR/21 - Urbanistica
Published
2004

30. Management of acute pharyngitis in children: summary of the Italian National Institute of Health guidelines

Author

Chiappini, E, Principi, N, Mansi, N, Serra, Agostino, De Masi, S, Camaioni, A, Esposito, S, Felisati, G, Galli, L, Landi, M, Speciale, Am, Bonsignori, F, Marchisio, P, de Martino, M, Collaborators Becherucci P, Italian Panel on the Management of Pharyngitis in C. h. i. l. d. r. e. n., Bellussi, L, De Gaudio, M, Di Simone, L, Di Mauro, G, Di Pietro, P, Festini, F, Gaini, Rm, Maiolino, Luigi, Mele, G, Marseglia, Gl, Novelli, A, Pisani, P, Puglisi, S, Rugiu, Mg, Tovo, Pa, Tulimiero, P, Varricchio, A, Venturini, E, Rosati, G. V., Chiappini, E, Principi, N, Mansi, N, Serra, A, De Masi, S, Camaioni, A, Esposito, S, Felisati, G, Galli, L, Landi, M, Speciale, A, Bonsignori, F, Marchisio, P, and de Martino, M

Subjects
Pediatrics, medicine.medical_specialty, MEDLINE, Acute Pharyngitis, Government Agencies, medicine, Humans, Pharmacology (medical), Child, Pharmacology, Acute Disease, Evidence-Based Medicine, Italy, Pharyngitis, Practice Guidelines as Topic, business.industry, Evidence-based medicine, Guideline, Amoxicillin, Government Agencie, Penicillin, Systematic review, Pharyngiti, medicine.symptom, business, medicine.drug, Human
Abstract

Background Discrepancies in the management of pharyngitis in children have been reported in Europe and the United States, and recommendations concerning the use of clinical scores, rapid antigen diagnostic tests (RADTs) or throat cultures, and the indications for antibiotic treatment largely differ. Objective This article summarizes the Italian guidelines on the management of pharyngitis in children issued by the National Institute of Health. Methods A multidisciplinary panel of experts (the Guidelines Development Group) developed and used a set of key questions to conduct a systematic review of the literature. Relevant publications in English were identified through a systematic review of MEDLINE and the Cochrane Database of Systematic Reviews from their inception through April 30, 2011. Final recommendations were scaled according to the Italian National Guidelines Program grading. Results Eighteen clinical questions were defined, and 44 recommendations were issued. None of the available scoring systems is sufficiently accurate to identify group A β-hemolytic streptococci (GABHS) pharyngitis in settings with low prevalence for rheumatic disease. RADT should be performed by trained personnel in every child with a history and signs/symptoms suggestive of GABHS pharyngitis. RADT is not recommended in children with a McIsaac score of 0 or 1 with ≥2 signs/symptoms suggestive of viral infection. Backup culture in children with negative RADT result is not recommended. Culture test with antibiotic susceptibility assay should be performed exclusively for epidemiologic purposes. Streptococcal antibody titers are of no value in diagnosing acute pharyngitis. Antibiotic therapy is recommended in microbiologically documented GABHS pharyngitis. Because penicillin V is not available in Italy, amoxicillin (50 mg/kg/d in 2–3 doses orally) for 10 days is the first choice of treatment. In noncompliant cases, benzathine penicillin may be administered. Although not routinely recommended due to the high cost and wide spectrum of activity, a 5-day course with a second-generation cephalosporin may be used in noncompliant cases. Macrolides should be limited to children with demonstrated type I hypersensitivity to penicillin. Ibuprofen or paracetamol is recommended for relief of pain or fever associated with discomfort. Because the carrier state is not associated with increased risk of suppurative complications and risk of GABHS transmission to contacts is minimal, the carrier state should never be investigated and treated. Recommendations for the management of suppurative complications are given. Conclusions This guideline provides a comprehensive, evidence based, tool for the diagnosis and therapy of acute pharyngitis in children.

Published
2012

31. Hypertension and migraine comorbidity: prevalence and risk of cerebrovascular events: evidence from a large, multicenter, cross-sectional survey in Italy (MIRACLES study)

Author

Mancia, G, Rosei, Ea, Ambrosioni, E, Avino, F, Carolei, A, Daccã², M, Di Giacomo, G, Ferri, C, Grazioli, I, Melzi, G, Nappi, G, Pinessi, L, Sandrini, G, Trimarco, B, Zanchin, G, MIRACLES Study Group List of collaborators: Rosei EA, Cerbo, R, Del Bene, E, Ferrari, A, Genco, S, Maggioni, F, Malatino, L, Martelletti, P, Nami, R, Palasciano, G, Prudenzano, Mp, Sarchielli, Paola, Volpe, M, Di Iulio, F, Fedele, A, Felli, V, Privitera, G, Abbattista, L, Altieri, A, Bellomo, Mn, Bellomo, P, Bonelli, D, Cappa, G, Cavone, E, De Bellis, A, De Mola, C, De Renzio PA, Di Cecco, G, Di Cosola, V, Di Lecce, G, Di Paola, S, Dileo, Cm, Ferrante, F, Gallo, A, Genchi, A, Grasso, N, Iacobellis, S, Lampugnani, F, Lettini, A, Mancini, A, Mariani, F, Martinelli, G, Martire, A, Mastandrea, A, Miccoli, Ma, Miolli, G, Nicassio, N, Panza, P, Romito, N, Roselli, Gc, Rossi, F, Santoro, G, Saracino, A, Savino, F, Silvestri, C, Stucci, N, Surgo, R, Tarì, G, Turchiano, S, Vigilante, C, Zamparella, M, Bariselli, M, Benedetto, G, Di Mauro, G, Di Pietro, C, Dragone, L, Emiliani, L, Erba, P, Guarnera, L, Maccarrone, R, Mauro, N, Palumbo, M, Pizzo, S, Quaggiotti, E, Rigoni, F, Romano, M, Rondi, G, Rossi, A, Tabaglio, E, Trapelli, F, Verzura, P, Zammarchi, G, Zecchi, F, Zucchi, R, Alessi, A, Bacci, E, Bianucci, S, Falorni, F, Foppa, L, Frati, A, Hili, Jl, Mij, R, Negro, P, Niccolini, N, Pini, C, Santangeli, S, Schirripa, E, Serni, R, Zucconi, E, Bartolomucci, M, Bontempo, F, Calegaro, E, Chiarinelli, M, Ciccarella, A, De Mattia, C, D'Innocenzo, C, Evangelista, P, Giammaria, A, Gizzi, M, Laglia, G, Lupi, R, Masciovecchio, L, Nattellis, A, Zugaro, A, Barbieri, G, Bellentani, G, Bertoli, R, Bolognesi, Mg, Borghi, R, Bronzini, G, Cassanelli, M, Cirsone, R, D'Urso, Ar, Gallina, Mp, Giroldi, L, Iancu, G, Mai, Mp, Manfredonia, M, Nappi, E, Onesti, L, Pini, P, Rubbiani, B, Sacco, R, Tripodi, A, Verna, A, Zini, C, Aldrigo, L, Bertamini, A, Bossone, V, Bovo, P, Bovo, R, Bozza, F, Danieli, M, Doriguzzi, Ma, Eifu', G, Fragasso, A, Francheo, R, Mayellaro, V, Moro, A, Rubiconi, D, Russo, S, Ventura, A, Zoccali, R, Abbate, G, Arcangelo, A, Battaglia, T, Buccoleri, G, Cardinale, C, Cardinale, G, D'Agati, P, D'Alessandro, R, Di Carlo, V, Di Garbo, V, Favuzza, M, Giovenco, E, Liberti, G, Mauceri, Ml, Miallo, C, Progno, Ma, Quartetti, G, Scimeca, S, Enrico, S, Spatafora, V, Spera, G, Viola, V, Vultaggio, G, Above, L, Ammirati, G, Barone, D, Brizzi, P, Callegari, S, Casari, G, Coronelli, M, Daccò, M, Deodato, D, Fortunato, A, Gabba, F, Grimaldi, D, Menini, M, Musolino, A, Negri, F, Orlandi, E, Pisani, G, Quattrocchi, P, Baglioni, G, Benedetti, W, Bensi, A, Berardi, M, Birgolotti, Mc, Buresta, R, Cimignoli, E, Coppini, B, Draghini, L, Germini, F, Grilli, P, Lindi, S, Mezzetti, S, Natali, R, Pannacci, V, Parretti, D, Petrelli, S, Scarponi, T, Sgrelli, V, Surace, Ma, Susta, A, Tedeschi, L, Urbani, A, Bennardo, S, Bitetti, R, Burgio, R, Caccamo, G, Cottonaro, C, Di Pasquale, S, Di Stefano, S, Drago, G, Gurrieri, G, La Rosa, F, La Terra Bella, B, Ottaviano, G, Ottaviano, V, Ruta, G, Sortino, F, Tidona, F, Tumino, A, Tumino, G, Tumino, M, Vitale, G, Maria Zelante RF, Annibali, A, Antognoli, L, Antonelli, P, Arcadi, Re, Bartolini, A, Bruschelli, C, Calvieri, A, Domeniconi, P, Fiumana, M, Frittaion, F, Lazzaro, M, Leardi, F, Leoni, M, Marini, G, Marri, G, Massari, R, Mazzei, N, Mocci, B, Mocci, M, Morelli, A, Nati, G, Sebastiano, Orifici, Maria Luisa Paoletti, Maurizio, Parisi, Massimo, Pergolini, Italo, Polce, Stefano Roberto Polce, Paolo, Questino, Francesco, Rossiello, Massimo, Sabatini, Tiziana, Volpe, Agnello, M, Antonaci, L, Antonucci, P, Avaltroni, R, Barbaro, N, Bartolone, L, Bertini, Ma, Blasi, P, Bruziches, V, Cannata, P, Cannone, A, Capuano, C, Carbonetti, M, Cianfriglia, S, Fanelli, R, Fazi, F, Gambioli, S, Giannini, M, Giannone, M, Guerriero, G, Lanza, L, Latino, C, Leporelli, M, Maresca, G, Matzuzzi, G, Milani, L, Mocci, A, Muccichini, L, Oliva, F, Palange, Ma, Pratticò, C, Re, M, Sagoni, E, Salciccia, S, Sciarretta, A, Silvi, C, Tranò, F, Tripiciano, P, Troccoli, A, Troysi, S, Ansaldi, S, Anselmi, F, Bianchini, C, Carletti, F, De Michelis, R, De Risi, E, Faglia, S, Fracassi, L, Franci, A, Lenzi, G, Loretti, M, Marchetti, F, Marrelli, G, Martellini, A, Moretti, A, Pieragalli, L, Sani, P, Scibilia, G, and Turillazzi, P.

Published
2011

32. Development of an algorithm for the management of cervical lymphadenopathy in children: Consensus of the Italian Society of Preventive and Social Pediatrics, jointly with the Italian Society of Pediatric Infectious Diseases and the Italian Society of Pediatric Otorhinolaryngology

Author

Chiappini, E, Camaioni, A, Benazzo, M, Biondi, A, Bottero, S, De Masi, S, Di Mauro, G, Doria, M, Esposito, S, Felisati, G, Felisati, D, Festini, F, Gaini, R, Galli, L, Gambini, C, Gianelli, U, Landi, M, Lucioni, M, Mansi, N, Mazzantini, R, Marchisio, P, Marseglia, G, Miniello, V, Nicola, M, Novelli, A, Paulli, M, Picca, M, Pillon, M, Pisani, P, Pipolo, C, Principi, N, Sardi, I, Succo, G, Tomà, P, Tortoli, E, Tucci, F, Varricchio, A, de Martino, M, Chiappini, E, Camaioni, A, Benazzo, M, Biondi, A, Bottero, S, De Masi, S, Di Mauro, G, Doria, M, Esposito, S, Felisati, G, Felisati, D, Festini, F, Gaini, R, Galli, L, Gambini, C, Gianelli, U, Landi, M, Lucioni, M, Mansi, N, Mazzantini, R, Marchisio, P, Marseglia, G, Miniello, V, Nicola, M, Novelli, A, Paulli, M, Picca, M, Pillon, M, Pisani, P, Pipolo, C, Principi, N, Sardi, I, Succo, G, Tomà, P, Tortoli, E, Tucci, F, Varricchio, A, and de Martino, M

Abstract

Cervical lymphadenopathy is a common disorder in children due to a wide spectrum of disorders. On the basis of a complete history and physical examination, paediatricians have to select, among the vast majority of children with a benign self-limiting condition, those at risk for other, more complex, diseases requiring laboratory tests, imaging and, finally, tissue sampling. At the same time, they should avoid expensive and invasive examinations when unnecessary. The Italian Society of Preventive and Social Pediatrics, jointly with the Italian Society of Pediatric Infectious Diseases, the Italian Society of Pediatric Otorhinolaryngology, and other Scientific Societies, issued a National Consensus document, based on the most recent literature findings, including an algorithm for the management of cervical lymphadenopathy in children. Methods: The Consensus Conference method was used, following the Italian National Plan Guidelines. Relevant publications in English were identified through a systematic review of MEDLINE and the Cochrane Database of Systematic Reviews from their inception through March 21, 2014. Results: Basing on literature results, an algorithm was developed, including several possible clinical scenarios. Situations requiring a watchful waiting strategy, those requiring an empiric antibiotic therapy, and those necessitating a prompt diagnostic workup, considering the risk for a severe underling disease, have been identified. Conclusion: The present algorithm is a practice tool for the management of pediatric cervical lymphadenopathy in the hospital and the ambulatory settings. A multidisciplinary approach is paramount. Further studies are required for its validation in the clinical field.

Published
2015

38. [Guidelines on acute otitis media]

Author

Marchisio, P., Principi, N., Bellussi, L., Di Mauro, G., Felisati, G., Conforti, G., Cunsolo, E., Doria, M., Longhi, R., Navone, C., Renna, S., Pignataro, L., Piemonte, M., Mariniello, L., Nicoletti, G., Speciale, A., De Vincentiis, G., Genovese, E., Mansi, N., Mele, G., Del Giudice, M. M., Novelli, A., Diana, M. C., Paravati, F., Scaglione, F., and Vitali-Rosati, G.

Subjects
Otitis Media, Acute Disease, Practice Guidelines as Topic, Humans, Child
Published
2009

47. Guidelines for the diagnosis and treatment of acute and subacute rhinosinusitis in children

Author

Di Pietro, P, Bona, G, Longhi, R, Navone, C, De Luca, G, Michelozzi, C, Miniello, V, Morelli, M, Tel, F, Traverso, A, Tremolati, E, de Martino, M, Bosis, S, Chiappini, E, Galli, L, Tovo, P, Paravati, F, Plebani, A, Vierucci, A, Barbato, A, Marseglia, G, Baldi, F, Barberi, S, Bellasio, M, Boner, A, Cuffari, A, Decimo, F, De Rosa, M, Leo, G, Longo, G, del Giudice MM, Piacentini, G, Tripodi, S, Di Mauro, G, Brusoni, G, Zuccotti, Gv, Passali, D, Serra, Agostino, Pagnataro, L, Bellussi, L, Marchisio, P, Eandi, M, Novelli, A, Scaglione, F, Nicoletti, G, and Speciale, A. M.

Published
2008

48. [Acute, subacute and recurrent bacterial rhinosinusitis in pediatrics: guidelines of the Study Group of the Italian Society for Pediatric Infectious Diseases (SITIP)]

Author

Esposito, Susanna Maria Roberta, Marseglie, G., Novelli, A., De Martino, M., Di Mauro, G., Gabiano, C., Galli, L., De Luca, G., Leo, G., Navone, C., Nicoletti, G., Passali, D., Serra, A., Vierucci, A., and Principi, N.

Subjects
Settore MED/38 - Pediatria Generale e Specialistica, Italy, Recurrence, Acute Disease, Humans, Communicable Diseases, Pediatrics, Societies, Medical, Rhinitis
Published
2007

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