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5. Tungsten sources and core contamination in WEST plasmas: from experiments to simulations

Author

Fedorczak, N, Di Genova, S, Guillemaut, C, Guirlet, R, Cappelli, L, Gallo, A, Colas, L, Romazanov, J, Brezinsek, S, Marandet, Y, Bufferand, H, Yang, H, Ciraolo, G, Serre, E, Unterberg, E, Klepper, C, Johnson, C, Donovan, D, Kosslow, S, Maker, J, Grosjean, A, Tsitrone, E, Bucalossi, J, CEA Cadarache, Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Institut de Recherche sur la Fusion par confinement Magnétique (IRFM), Aix Marseille Université (AMU), Forschungszentrum Jülich GmbH, Physique des interactions ioniques et moléculaires (PIIM), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), CEA- Saclay (CEA), Laboratoire de Mécanique, Modélisation et Procédés Propres (M2P2), Aix Marseille Université (AMU)-École Centrale de Marseille (ECM)-Centre National de la Recherche Scientifique (CNRS), Oak Ridge National Laboratory [Oak Ridge] (ORNL), UT-Battelle, LLC, The University of Tennessee [Knoxville], and icard, valerie

Subjects
[PHYS]Physics [physics], [PHYS.PHYS.PHYS-PLASM-PH]Physics [physics]/Physics [physics]/Plasma Physics [physics.plasm-ph], [PHYS.PHYS.PHYS-PLASM-PH] Physics [physics]/Physics [physics]/Plasma Physics [physics.plasm-ph], [PHYS] Physics [physics]
Abstract

International audience

Published
2022

6. Operating a full tungsten actively cooled tokamak: overview of WEST first phase of operation

Author

Bucalossi, J., Achard, J., Agullo, O., Alarcon, T., Allegretti, L., Ancher, H., Antar, G., Antusch, S., Anzallo, V., Arnas, C., Arranger, D., Artaud, J. F., Aumeunier, M. H., Baek, S. G., Bai, X., Balbin, J., Balorin, C., Barbui, T., Barbuti, A., Barlerin, J., Basiuk, V., Batal, T., Baulaigue, O., Bec, A., Bécoulet, M., Benoit, E., Benard, E., Benard, J. M., Bertelli, N., Bertrand, E., Beyer, P., Bielecki, J., Bienvenu, P., Bisson, R., Bobkov, V., Bodner, G., Bottereau, C., Bouchand, C., Bouquey, F., Bourdelle, C., Bourg, J., Brezinsek, S., Brochard, F., Brun, C., Bruno, V., Bufferand, H., Bureau, A., Burles, S., Camenen, Y., Cantone, B., Caprin, E., Carpentier, S., Caulier, G., Chanet, N., Chellai, O., Chen, Y., Chernyshova, M., Chmielewski, P., Choe, W., Chomiczewska, A., Ciraolo, G., Clairet, F., Coenen, J., Colas, L., Colledani, G., Colnel, J., Coquillat, P., Corbel, E., Corre, Y., Costea, S., Courtois, X., Czarski, T., Daniel, R., Daumas, J., De Combarieu, M., Temmerman, G., De, De Vries, P., Dechelle, C., Deguara, F., Dejarnac, R., Delaplanche, J. M., Delgado-Aparicio, L. F., Delmas, E., Delpech, L., Desgranges, C., Devynck, P., Di Genova, S., Diab, R., Diallo, A., Diez, M., Dif-Pradalier, G., Dimitrova, M., Ding, B., Dittmar, T., Doceul, L., Domenes, M., Douai, D., Dougnac, H., Duan, X., Dubus, L., Dumas, N., Dumont, R., Durand, F., Durif, A., Durocher, A., Durodié, F., Ekedahl, A., Elbeze, D., Ertmer, S., Escarguel, A., Escourbiac, F., Ezato, K., Faisse, F., Faure, N., Fedorczak, N., Fejoz, P., Fenzi-Bonizec, C., Ferlay, F., Firdaouss, M., Fleury, L., Flouquet, D., Gallo, A., Gao, Y., Garbet, X., Garcia, J., Gardarein, J. L., Gargiulo, L., Garibaldi, P., Garitta, S., Gaspar, J., Gauthier, E., Gavila, P., Gazzotti, S., Gely, F., Geynet, M., Gharafi, S., Ghendrih, P., Giacalone, I., Gil, C., Ginoux, S., Girard, S., Giroux, E., Giruzzi, G., Goletto, C., Goniche, M., Gray, T., Grelier, E., Greuner, H., Grigore, E., Grisolia, C., Grosjean, A., Grosman, A., Guibert, D., Guilhem, D., Guillemaut, C., Guillermin, B., Guirlet, R., Gunn, J. P., Gunsu, Y., Gyergyek, T., Hakola, A., Harris, J., Hatchressian, J. C., Helou, W., Hennequin, P., Hernandez, C., Hill, K., Hillairet, J., Hirai, T., Hoang, G. T., Houry, M., Hutter, T., Imbeaux, F., Imbert, N., Ivanova-Stanik, I., Jalageas, R., Jardin, A., Jaubert, L., Jiolat, G., Jonas, A., Joubert, P., Kirschner, A., Klepper, C., Komm, M., Koubiti, M., Kovacic, J., Kozeiha, M., Krieger, K., Krol, K., Lacroix, B., Laguardia, L., Lamaison, V., Laqua, H., Lau, C., Lausenaz, Y., Lé, R., Le Bohec, M., Lefevre, N., Lemoine, N., Lerche, E., Lewerentz, M., Li, Y., Li, M., Liang, A., Linczuk, P., Linsmeier, C., Lipa, M., Litaudon, X., Liu, X., Llorens, J., Loarer, T., Loarte, A., Loewenhoff, T., Lombard, G., Lore, J., Lorenzetto, P., Lotte, P., Lozano, M., Lu, B., Lunsford, R., Luo, G., Magaud, P., Maget, P., Mahieu, J. F., Maini, P., Malard, P., Malinowski, K., Manas, P., Manenc, L., Marandet, Y., Marechal, J. L., Marek, S., Martin, C., Martin, E., Martinez, A., Martino, P., Mazon, D., Messina, P., Meunier, L., Midou, D., Mineo, Y., Missilian, M., Mitteau, R., Mitu, B., Mollard, P., Moncada, V., Mondiere, T., Morales, J., Moreau, M., Moreau, P., Moudden, Y., Moureau, G., Mouyon, D., Muraglia, M., Nagy, A., Nakano, T., Nardon, E., Neff, A., Nespoli, F., Nichols, J., Nicollet, S., Nouailletas, R., Ono, M., Ostuni, V., Parish, C., Park, H., Parrat, H., Pascal, J. Y., Pégourié, B., Pellissier, F. P., Peneliau, Y., Peret, M., Peysson, Y., Pignoly, E., Pintsuk, G., Pitts, R., Pocheau, C., Portafaix, C., Poulos, M., Prochet, P., Puig Sitjes, A., Rasinski, M., Raup, G., Regal-Mezin, X., Reux, C., Riccardi, B., Rice, J., Richou, M., Rigollet, F., Roche, H., Romazanov, J., Ruset, C., Sabot, R., Saille, A., Sakamoto, R., Salmon, T., Samaille, F., Santagiustina, A., Santraine, B., Sarazin, Y., Serre, E., Shin, H., Shiraiwai, S., Signoret, Ja., Signoret, Je., Simonin, A., Skalli Fettachi, O., Song, Y., Spring, A., Spuig, P., Sridhar, S., Stratton, B., Talatizi, C., Tamain, P., Tatali, R., Téna, M., Torre, A., Toulouse, L., Travère, J. M., Treutterer, W., Tsitrone, E., Unterberg, E., Urbanczyk, G., Van Eester, D., Van Rooij, G., Vartanian, S., Verger, J. M., Vermare, L., Vézinet, D., Vignal, N., Vincent, B., Vives, S., Volpe, D., Wallace, G., Wang, E., Wang, L., Wang, Yi., Wang, Yo., Wauters, T., Wirth, B., Wirtz, M., Wojenski, A., Wright, J., Xu, M., Yang, Q., Yang, H., Zago, B., Zagorski, Zhang, B., Zhang, X., Zou, X., Institut universitaire des systèmes thermiques industriels (IUSTI), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Institut de Recherche sur la Fusion par confinement Magnétique (IRFM), Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Laboratoire de Physique des Plasmas (LPP), Observatoire de Paris, and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-École polytechnique (X)-Sorbonne Université (SU)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)

Subjects
Nuclear and High Energy Physics, Tokamak, Materials science, WEST, Nuclear engineering, Phase (waves), chemistry.chemical_element, Tungsten, law.invention, [PHYS.PHYS.PHYS-PLASM-PH]Physics [physics]/Physics [physics]/Plasma Physics [physics.plasm-ph], law, ITER, divertor, DEMO, Engineering & allied operations, nuclear fusion, Superconductivity, [PHYS]Physics [physics], Divertor, RF power amplifier, magnetic confinement, Plasma, Condensed Matter Physics, chemistry, Heat flux, ddc:620, tokamak physics
Abstract

WEST is an MA class superconducting, actively cooled, full tungsten (W) tokamak, designed to operate in long pulses up to 1000 s. In support of ITER operation and DEMO conceptual activities, key missions of WEST are: (i) qualification of high heat flux plasma-facing components in integrating both technological and physics aspects in relevant heat and particle exhaust conditions, particularly for the tungsten monoblocks foreseen in ITER divertor; (ii) integrated steady-state operation at high confinement, with a focus on power exhaust issues. During the phase 1 of operation (2017–2020), a set of actively cooled ITER-grade plasma facing unit prototypes was integrated into the inertially cooled W coated startup lower divertor. Up to 8.8 MW of RF power has been coupled to the plasma and divertor heat flux of up to 6 MW m−2 were reached. Long pulse operation was started, using the upper actively cooled divertor, with a discharge of about 1 min achieved. This paper gives an overview of the results achieved in phase 1. Perspectives for phase 2, operating with the full capability of the device with the complete ITER-grade actively cooled lower divertor, are also described.

Published
2022

7. Interpretative modeling of impurity transport and tungsten sources in WEST boundary plasma

Author

Ciraolo, G., primary, Di Genova, S., additional, Yang, H., additional, Gallo, A., additional, Fedorczak, N., additional, Bufferand, H., additional, Gunn, J.P., additional, Tamain, P., additional, Guirlet, R., additional, Guillemaut, C., additional, Desgranges, C., additional, Bourdelle, C., additional, Tsitrone, E., additional, Bucalossi, J., additional, Scotto D’Abusco, M., additional, Serre, E., additional, Marandet, Y., additional, Raghunathan, M., additional, Sepetys, A., additional, Romazanov, J., additional, Kirschner, A., additional, Brezinsek, S., additional, and WEST Team, the, additional

Published
2021
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8. INTERPRETATIVE MODELING OF IMPURITY TRANSPORT AND TUNGSTEN SOURCES IN WEST BOUNDARY PLASMA

Author

Ciraolo, Guido, Di Genova, S., Gallo, Alberto, Fedorczak, Nicolas, Bucalossi, Jérôme, Bufferand, Hugo, Yang, Hao, Marandet, Yannick, Sepetys, Arvydas, Corre, Yann, Desgranges, Corinne, Guirlet, Remy, Guillemaut, Christophe, Gunn, J.P., Tamain, Patrick, Romazanov, J., Brezinsek, S, Klepper, C.C., Tsitrone, Emmanuelle, Institut de Recherche sur la Fusion par confinement Magnétique (IRFM), Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Physique des interactions ioniques et moléculaires (PIIM), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Forschungszentrum Jülich GmbH | Centre de recherche de Juliers, Helmholtz-Gemeinschaft = Helmholtz Association, Oak Ridge National Laboratory [Oak Ridge] (ORNL), UT-Battelle, LLC, WEST team - http://west.cea.fr/WESTteam, European Project: 633053,H2020,EURATOM-Adhoc-2014-20,EUROfusion(2014), icard, valerie, and Implementation of activities described in the Roadmap to Fusion during Horizon 2020 through a Joint programme of the members of the EUROfusion consortium - EUROfusion - - H20202014-01-01 - 2018-12-31 - 633053 - VALID

Subjects
[PHYS]Physics [physics], [PHYS.PHYS.PHYS-PLASM-PH]Physics [physics]/Physics [physics]/Plasma Physics [physics.plasm-ph], [PHYS.PHYS.PHYS-PLASM-PH] Physics [physics]/Physics [physics]/Plasma Physics [physics.plasm-ph], ComputingMilieux_MISCELLANEOUS, [PHYS] Physics [physics]
Abstract

International audience

Published
2021

9. Manlio Sargenti: ricordi della sua vita e del suo insegnamento all'Università di Pavia

Author

Di Genova, S, Martini, R, Cuneo, PO, Pergami, F, Cuneo, P, CUNEO, PAOLA OMBRETTA, Di Genova, S, Martini, R, Cuneo, PO, Pergami, F, Cuneo, P, and CUNEO, PAOLA OMBRETTA

Abstract

In occasione del centenario della nascita di un Maestro nel diritto romano, Manlio Sargenti, si ricorda la sua vita, il suo insegnamento nel diritto romano, la sua attività scientifica

Published
2017

13. Prevalence of severe sepsis in Intensive Care Units. A national multicentric study,Prevalencia de sepsis grave en las Unidades de Cuidado Intensivo. Primer estudio nacional multicéntrico

Author

Dougnac L, A., Mercado F, M., Cornejo R, R., Cariaga V, M., Hernández P, G., Max Andresen, Bugedo T, G., Castillo F, L., Vásquez, L., Becerra, J., Mella R, M., Montalvo, D., Romero, R., Moreno, D., Gómez, M., Illanes, G., Crespo, F., Maurelia, J. C., Añazco, J., Ugarte, H., Arab, F., Gálvez, S., Caballero, M. T., Di Genova, S., Toro, M., Cantero, J., Jara, J., Llancaqueo, A., Herrera, E., Colima, R., Ortega, C., Müller, H., Dapelo, A., Fuentes, E., Monsalve, M., Urra, J., Saavedra, J., Calvo, M., Scholz, L., Rojas, C., Umaña, A., Arenas, P., Gómez, X., Varnava, C., Tomicic, V., Alamo, M., Gonzales, A., Carcomo, C., Núñez, G., Sáez, E., Huerta, G., Hassi, M., Ugarte, S., Soto, L., Heiremans, G., Castro, J., Soto, R., Romero, C., Hernández, A., Muñoz, A., Villamizar, G., Arenas, G., Alfaro, M., Gonzales, H., Godoy, J., Bugedo, G., Mercado, M., Alarcón, C., Valdés, S., and Chávez, E.

14. Manlio Sargenti: ricordi della sua vita e del suo insegnamento all'Università di Pavia

Author

CUNEO, PAOLA OMBRETTA, Di Genova, S, Martini, R, Cuneo, PO, Pergami, F, and Cuneo, P

Subjects
Diritto romano, Tardo Impero, Accademia Romanistica Costantiniana, IUS/18 - DIRITTO ROMANO E DIRITTI DELL'ANTICHITA
Abstract

In occasione del centenario della nascita di un Maestro nel diritto romano, Manlio Sargenti, si ricorda la sua vita, il suo insegnamento nel diritto romano, la sua attività scientifica

Published
2017

15. Establishing an Updated Core Domain Set for Studies in Juvenile Idiopathic Arthritis: A Report from the OMERACT 2018 JIA Workshop.

Author

Morgan EM, Munro JE, Horonjeff J, Horgan B, Shea B, Feldman BM, Clairman H, Bingham CO 3rd, Thornhill S, Strand V, Alongi A, Magni-Manzoni S, van Rossum MAJ, Vesely R, Vojinovic J, Brunner HI, Harris JG, Horton DB, Lovell DJ, Mannion M, Rahimi H, Ravelli A, Ringold S, Ruperto N, Schrandt MS, Shenoi S, Shiff NJ, Toupin-April K, Tzaribachev N, Weiss P, and Consolaro A

Subjects
Adolescent, Australia, Clinical Trials as Topic, Female, Humans, Italy, Male, Outcome Assessment, Health Care, Treatment Outcome, United States, Young Adult, Antirheumatic Agents therapeutic use, Arthritis, Juvenile drug therapy, Patient Reported Outcome Measures
Abstract

Objective: The current Juvenile Idiopathic Arthritis (JIA) Core Set used in randomized controlled trials (RCT) and longitudinal observational studies (LOS) was developed without the input of patients/parents. At the Outcome Measures in Rheumatology (OMERACT) 2016, a special interest group voted to reconsider the core set, incorporating broader input. We describe subsequent work culminating in an OMERACT 2018 plenary and consensus voting., Methods: Candidate domains were identified through literature review, qualitative surveys, and online discussion boards (ODB) held with patients with JIA and parents in Australia, Italy, and the United States. A Delphi process with parents, patients, healthcare providers, researchers, and regulators served to edit the domain list and prioritize candidate domains. After the presentation of results, OMERACT workshop participants voted, with consensus set at > 70%., Results: Participants in ODB were 53 patients with JIA (ages 15-24 yrs) and 55 parents. Three rounds of Delphi considering 27 domains were completed by 190 (response rate 85%), 201 (84%), and 182 (77%) people, respectively, from 50 countries. There was discordance noted between domains prioritized by patients/parents compared to others. OMERACT conference voting approved domains for JIA RCT and LOS with 83% endorsement. Mandatory domains are pain, joint inflammatory signs, activity limitation/physical function, patient's perception of disease activity (overall well-being), and adverse events. Mandatory in specific circumstances: inflammation/other features relevant to specific JIA categories., Conclusion: Following the OMERACT methodology, we developed an updated JIA Core Domain Set. Next steps are to identify and systematically evaluate best outcome measures for these domains.

Published
2019
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16. Clinical Characteristics of Patients Carrying the Q703K Variant of the NLRP3 Gene: A 10-year Multicentric National Study.

Author

Naselli A, Penco F, Cantarini L, Insalaco A, Alessio M, Tommasini A, Maggio C, Obici L, Gallizzi R, Cimmino M, Signa S, Lucherini OM, Carta S, Caroli F, Martini A, Rubartelli A, Ceccherini I, and Gattorno M

Subjects
Adolescent, Adult, Arthralgia genetics, Arthralgia metabolism, Child, Child, Preschool, Cryopyrin-Associated Periodic Syndromes complications, Cryopyrin-Associated Periodic Syndromes genetics, Cytokines metabolism, Exanthema genetics, Exanthema metabolism, Female, Humans, Infant, Male, Middle Aged, Monocytes metabolism, Young Adult, Arthralgia etiology, Cryopyrin-Associated Periodic Syndromes diagnosis, Exanthema etiology, Mutation, NLR Family, Pyrin Domain-Containing 3 Protein genetics, Phenotype
Abstract

Objective: The aim of our study was to analyze the clinical and functional effect of the p.Q703K (p. Q705K, c. 2107C>A) variant of the NLRP3 gene in a population of patients screened for suspected cryopyrin-associated periodic syndrome (CAPS)., Methods: Since 2002, 580 patients underwent molecular analysis for NLRP3. Data on clinical presentation, response to treatment, and longterm followup were collected using a uniform questionnaire. The pattern of cytokine secretion after lipopolysaccharide stimulation from isolated monocytes was analyzed in 3 patients carrying the p.Q703K variant and 1 patient with a chronic infantile neurologic, cutaneous, articular syndrome phenotype carrying both the p.M406I and p.Q703K, and compared with 7 patients with CAPS with sure pathogenic variants and 6 healthy controls., Results: The p.Q703K variant was found in 57 screened patients with an overall allelic frequency of 5%. The frequency in normal controls was 5.5%. Clinical data at the moment of molecular analysis and at followup were available in 36 patients. Two patients displayed additional mutations of NLRP3. The mean followup was 2.5 years. Thirteen patients (39%) had a final diagnosis different from the original suspicion of CAPS. The remaining 21 patients displayed a mild phenotype mainly characterized by recurrent episodes of urticarial rash and arthralgia. Only 8 patients were treated with anti-interleukin (IL)-1 treatment, with a complete response in 5 patients. The pattern of secretion of IL-1β and other cytokines (IL-6 and IL-1 receptor antagonist) in patients did not display the aberrancies observed in patients with CAPS and was similar to that observed in healthy controls., Conclusion: The present study confirms the weak clinical and functional effect of the p.Q703K variant.

Published
2016
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17. [The effect of subgingival irrigation with acetylsalicylate on the polymorphonuclear leukocyte count in periodontal pockets of medium depth].

Author

Paolantonio M, Fanali S, and Di Genova S

Subjects
Adult, Chi-Square Distribution, Drug Evaluation, Female, Humans, Leukocyte Count drug effects, Male, Middle Aged, Periodontal Index, Solutions, Therapeutic Irrigation statistics & numerical data, Aspirin administration & dosage, Gingiva, Neutrophils drug effects, Periodontal Pocket drug therapy
Abstract

Considering the role played by arachidonic acid metabolites in the pathogenesis of periodontal disease and the possible beneficial effects exerted by non steroidal anti inflammatory drugs on periodontal damage, the aim of the present study was to assess the capability of a 1% acetylsalicylate solution, delivered by subgingival irrigation, in reducing the number of polymorphonuclear leukocytes (PMN) in periodontal pockets of patients affected by periodontitis. Ten patients systemically healthy, in the age between 36 and 64, participated in the study. After supragingival scaling in each patient test and two control sites were chosen among those exhibiting a pocket depth between 5 and 7 mm. The number of periodontal pocket PMN was evaluated after subgingival washing by the technique of Skapski & Lenher and Gingival Bleeding Index (GBI) score was recorded in each experimental site. Test sites then received subgingival subgingival washing by 0.5 ml of a 1% acetylsalicylate solution three times a week whereas control sites were irrigated by physiologic solution. After treatment the number of PMN and GBI scores from each test and control site was re-evaluated. Results showed that test sites exhibited a decrease in the number of pocket-PMN respect to control sites although not statistically significant (p > 0.5). At contrary GBI score did not modify through the study. In conclusion subgingival irrigation by acetylsalicylate demonstrated to be able to reduce subclinical inflammation in periodontal pockets evaluated by the number of PMN in gingival fluid.

Published
1995

18. [The presence of Actinobacillus actinomycetemcomitans in subgingival bacterial plaque in relation to the amount of supragingival plaque].

Author

Paolantonio M, Fanali S, Di Girolamo G, and Di Genova S

Subjects
Adolescent, Adult, Chi-Square Distribution, Child, Colony Count, Microbial statistics & numerical data, Confidence Intervals, Dental Plaque Index, Female, Humans, Male, Periodontal Index, Random Allocation, Aggregatibacter actinomycetemcomitans isolation & purification, Dental Plaque microbiology, Gingiva microbiology
Abstract

Actinobacillus actinomycetemcomitans (Aa) is currently considered the principal bacterium involved in juvenile forms of periodontitis. Considering that supragingival and subgingival plaque are closely correlated, the aim of the present research has been to assess if a correlation can be recognized between the amount of supragingival plaque and the presence of Aa in subgingival plaque in young subjects. Thirty-three individuals participated in the study. In each subject's dentition two periodontal sites were chosen: one (test site) was randomly selected among those sites which displayed a Plaque Index (P1I) = 0; another site was similarly chosen among those which presented the highest P1I score (2 or 3). In each test and control site Gingival Bleeding Index (GBI) was recorded and a microbiological sampling of subgingival plaque was performed. After anaerobic culture of plaque samples, the occurrence of Aa in each test and control site and the proportional representation of the bacterium in total cultivable anaerobic flora were assessed. Results showed a statistically significant difference in the occurrence of Aa between test and control sites in the same oral cavity and a correlation between GBI positivity and Aa presence. In conclusion, according to other authors, Aa seems to be more frequently founded in subgingival plaque coming from periodontal sites where supragingival plaque in more abundant.

Published
1995

19. Technique and endoscopic monitoring of the healing process in bilioenteric anastomoses.

Author

Gazzaniga GM, Faggioni A, Pastorino G, Bondanza G, Filauro M, Bagarolo C, and Moretti G

Subjects
Adult, Aged, Anastomosis, Surgical methods, Bile Duct Diseases surgery, Cholelithiasis surgery, Female, Humans, Male, Middle Aged, Suture Techniques, Bile Ducts surgery, Jejunum surgery, Wound Healing
Abstract

Thirty-three patients were given cholangiojejunoanastomoses: 13 for benign postoperative stenoses of the biliary tract (BT) with or without lithiasis; five for massive intra and extra-hepatic lithiasis; 15 for malignant stenoses on the upper third of the biliary ways. The 15 patients in Group A were given a muco-mucosal anastomosis and the 18 in Group B extramucosal anastomosis after excision of the excess mucosa on the jejunotomy. In both groups an interrupted suture using fine, slow-absorption thread was employed. Three patients (two from Group A and one from Group B) were excluded from the study due to postoperative filtration of the anastomosis. Transhepatic cholangioscopic monitoring of the healing process on the 15th, 20th, 30th and 40th day showed that while both types of anastomosis were equally secure, the extramucosal suture after excision of excess mucosa produced wider anastomoses and is therefore advisable in all cases of bilioenteric anastomosis (BEA) but especially when the biliary ways are narrow or tendentially thin-walled.

Published
1987

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