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4. Factors Affecting Patency of In Situ Saphenous Vein Bypass: Two Year Results from LIMBSAVE (Treatment of critical Limb Ischaemia with infragenicular Bypass adopting in situ SAphenous VEin technique) Registry

Author

Accrocca, Federico, Amico, Alessio, Angelini, Andrea, Arnuzzo, Luca, Marchetti, Andrea Ascoli, Attisani, Luca, Bafile, Gennaro, Baldino, Giuseppe, Barbanti, Enrico, Bartoli, Stefano, Bellosta, Raffaello, Benedetto, Filippo, Borioni, Raoul, Briolini, Franco, Busoni, Cristina, Camparini, Stefano, Cappiello, Pierluigi, Carbonari, Luciano, Casella, Francesco, Celoria, Giovanni, Chiama, Andrea, Chisci, Emiliano, Civilini, Efrem, Codispoti, Francesco, Conti, Barbara, Coppi, Giovanni, De Blasis, Giovanni, D’Elia, Marcello, Di Domenico, Rossella, Di Girolamo, Carla, Ercolini, Leonardo, Ferrari, Alessandra, Ferrari, Mauro, Forliti, Enzo, Frigatti, Paolo, Frigerio, Dalmazio, Frosini, Pierfrancesco, Garriboli, Luca, Giordano, Antonio Nicola, Guerrieri, Walter, Jannello, Antonio, Massara, Mafalda, Merlo, Maurizio, Mezzetti, Roberto, Miccoli, Tommaso, Milite, Domenico, Mingazzini, Pietro, Muncinelli, Marina, Nano, Giovanni, Natola, Marco, Novali, Claudio, Palasciano, Giancarlo, Perkmann, Reinhold, Persi, Federica, Petruccelli, David, Pinelli, Mauro, Poletto, Giorgio, Porta, Carla, Pratesi, Carlo, Pruner, Gianguido, Ragazzi, Giovanni, Righini, Paolo, Salvini, Mauro, Scovazzi, Paolo, Setacci, Carlo, Settembrini, Alberto Maria, Siani, Andrea, Silingardi, Roberto, Silvestro, Antonino, Talarico, Francesco, Tolva, Valerio, Trani, Antonio, Trimarchi, Santi, Tshomba, Yamume, Vigliotti, Gennaro, Viola, Daniela, Volpe, Pietro, Zani, Federico, Troisi, Nicola, Adami, Daniele, Michelagnoli, Stefano, and Berchiolli, Raffaella

Published
2022
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5. The Gore Viabahn balloon-expandable stent graft as a bridging stent in complex endovascular aortic procedures at 3 years performs better in fenestrations.

Author

Di Domenico, Rossella, Esposito, Davide, Speziali, Sara, Dorigo, Walter, Pratesi, Carlo, Pulli, Raffaele, and Fargion, Aaron Thomas

Abstract

Complex endovascular procedures are now recognized as the gold standard treatments for extensive aortic diseases. Bridging stents (covered stents used to couple the aortic graft to the visceral vessels) play a pivotal role, yet there is currently no dedicated device available on the market. The aim of the study was to evaluate the midterm performance of the Gore Viabahn balloon-expandable (VBX) stent graft as a bridging stent for target visceral vessels (TVVs). Data from all consecutive patients who underwent a fenestrated and branched endovascular aortic repair and received the VBX stent graft as a bridging stent between July 2018 and September 2022 were prospectively collected and subsequently analyzed retrospectively. Primary end points included freedom from TVV instability and freedom from TVV-related reinterventions, both overall and in comparison between branched and fenestrated graft configurations. Secondary end points were overall survival, procedure and TVV-related (in an intent-to-treat basis) technical success, freedom from type IC/IIIC endoleak, and freedom from TVV patency loss. Sixty-three patients were treated with a fenestrated and branched endovascular aortic repair using the VBX stent graft as a bridging stent, of whom 47 (74.6%) presented an atherosclerotic aneurysm, 7 (11.1%) a post-dissecative aneurysm, and 9 (14.3%) an anastomotic pseudoaneursym or a type IA endoleak in a previous endovascular aortic repair. Included in the aortic repair were 231 of 243 (95.1%) total visceral vessels. The intraoperative requirement of 13 additional VBX stent grafts determined a TVV-related technical success of 94.4%. The mean follow-up was 26.1 ± 16.4 months. The estimated overall survival at 36 months was 73% ± 7.5%. The estimated rates at 36 months for freedom from type IC/IIIC endoleaks and TVV primary patency were 90.6% ± 3.9% and 99% ± 0.7%, respectively. The estimated rate at 36 months for freedom from TVV instability was 92.1% ± 3% and did not differ between branched and fenestrated configurations, whereas freedom from TVV-related reinterventions was 90.6% ± 3.1% and significantly in favor of fenestrations (69.4% vs 96.8%, P <.001). Multivariate analyses confirmed fenestrated configuration as a protective factor against TVV-related reinterventions (hazard ratio: 0.079; 95% confidence interval: 0.016-0.403). The VBX stent graft proves to be a reliable bridging stent for complex aortic procedures involving both fenestrated and branched endografts. Although immediate results are deemed satisfactory, they favor fenestrations regarding the need of reinterventions through 3 years. The success of the procedure heavily relies on a thorough understanding of the unique characteristics of this stent. [ABSTRACT FROM AUTHOR]

Published
2024
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7. Insight from an Italian Delphi Consensus on EVAR feasibility outside the instruction for use: the SAFE EVAR Study

Author

Sirignano, P, Piffaretti, G, Ceruti, S, Orso, M, Picozzi, M, Ricci, G, Sirignano, A, Taurino, M, Giancarlo Accarino, M, Accrocca, F, Alba, G, Alberti, A, Alberti, V, Allevi, S, Aloisi, F, Amato, B, Amico, A, Andreoli, F, Angiletta, D, Antico, A, Antico, L, Antonello, M, Baccellieri, D, Badalamenti, G, Bafile, G, Baldi, C, Barillà, C, Barillà, D, Bartoli, S, Basile, G, Battaglia, G, Battocchio, C, Belloni, A, Bellosta, R, Benevento, D, Bernardini, G, Bertagna, G, Bertoglio, L, Bianchini Massoni, C, Bisacco, D, Bischetti, M, Boccalon, L, Bonanno, P, Bonardelli, S, Borioni, R, P Borrelli, M, Bozzani, A, M Bracale, U, Camparini, S, Canciglia, A, Canova, F, Capoccia, L, Cappelli, A, Cappiello, P, Carluccio, C, Casalino, A, Casella, F, Casilli, G, Castagno, C, Castelli, P, Castrucci, T, Cavallo, M, Cavazzini, C, Ceccanei, G, Cefalì, P, Celoria, G, Cevolani, M, Chiappa, R, Chisci, E, Comande, C, Compagna, R, Cumino, A, Cuozzo, S, Dalla Caneva, P, D'Alessio, I, D'Arrigo, G, DE Caridi, G, DE Donato, G, DE Donno, G, Desantis, C, DE Santis, F, DE Troia, A, Dezi, T, A Diaco, D, DI Domenico, R, DI Filippo, M, DI Girolamo, A, P Dionisi, C, Dinoto, E, DI Stefano, F, DI STEFANO, L, D'Oria, M, Esposito, A, Esposito, D, Ettore, L, F Fadda, G, Faggioli, G, T Fargion, A, Fazzini, S, Fermani, N, Ferrante, G, Ferrari, M, Ferraro, S, Ferrer, C, Ferretto, L, Ficarelli, I, Filippi, F, Fino, G, Forliti, E, Formiconi, M, Flora, L, Fresilli, M, Frigatti, P, Frigerio, D, Froio, A, Freyrie, A, Furgiuele, S, Gabrielli, R, Gaggiano, A, Galassi, L, Gallelli, G, Gallitto, E, Gallo, F, Galzerano, G, Gargiulo, M, Garriboli, L, G Genadiev, G, Gentile, L, Giaquinta, A, Gibello, L, Grande, R, Grassi, V, Ippoliti, A, Irsara, S, Kahlberg, A, Konstantinos, N, LA Corte, F, Lanza, G, Lauricella, A, Lazzeri, E, Lenti, M, Leopardi, M, Lepidi, S, Li Destri, A, Locatelli, F, Lomazzi, C, Lombardi, F, Lorido, A, Maggiore, C, Mansour, W, Marcucci, V, Mascia, D, Massara, M, Mastrangelo, G, Margheritini, C, Maritati, G, Martelli, E, Martinelli, O, Marzano, A, Mauri, F, Mazzacaro, D, Melloni, A, Mezzetti, R, Michelagnoli, S, Migliara, B, Migliari, M, Millarelli, M, Misuraca, M, Modugno, P, Moniaci, D, Montelione, N, Monti, A, Monzio-Compagnoni, N, Moro, M, Mortola, L, Mozzetta, G, Musilli, A, Nano, G, Occhiuto, M, M Oddi, F, Orellana, B, Orlando, P, Orrico, M, A Pacilè, M, Pagliariccio, G, Pallini, C, Palmieri, A, Palughi, M, Panagrasso, M, Panzano, C, Panzera, C, Pascucci, F, Pasqua, R, Pasquetti, L, Pasqui, E, Pecchio, A, Pecoraro, F, Peluttiero, I, F Pennetta, F, Perini, P, Piazza, M, Pini, R, Pipito, N, Pranteda, C, Praquin, B, Pratesi, C, F Porreca, C, Pulli, R, Reina, N, F Rinaldi, L, Rizzo, L, Romano, E, Ronchey, S, Ruggiero, F, Ruggiero, M, Sallustro, M, Saviane, G, Sbarigia, E, Scovazzi, P, M Segramor, V, Sena, G, Setacci, C, Setacci, F, E Setteducati, C, M Settembrini, A, Siani, A, Sica, S, Speziale, F, Squizzato, F, Stella, N, Stilo, F, Sufali, G, Tanda, E, Tinelli, G, Tomei, F, Tosti, F, Trimarchi, S, Troisi, N, Tshomba, Y, Turchino, D, Turriziani, V, Ucci, A, Veneto, V, Veraldi, G, Wiesel, P, Xodo, A, Zacà, S, Zaraca, F, Zenunaj, G, SIRIGNANO, Pasqualino, PIFFARETTI, Gabriele, CERUTI, Silvia, ORSO, Massimiliano, PICOZZI, Mario, RICCI, Giovanna, SIRIGNANO, Ascanio, TAURINO, Maurizio, Giancarlo Accarino, Maurizio, Accrocca, Federico, Alba, Giuseppe, Alberti, Antonino, Alberti, Vittorio, Allevi, Sara, Aloisi, Francesco, Amato, Bruno, Amico, Alessio, Andreoli, Francesco, Angiletta, Domenico, Antico, Antonio, Antico, Lorenzo, Antonello, Michele, Baccellieri, Domenico, Badalamenti, Giovanni, Bafile, Gennaro, Baldi, Claudio, Barillà, Chiara, Barillà, David, Bartoli, Stefano, Basile, Giusi, Battaglia, Giuseppe, Battocchio, Cesare, Belloni, Ailin, Bellosta, Raffello, Benevento, Domenico, Bernardini, Giulia, Bertagna, Giulia, Bertoglio, Luca, Bianchini Massoni, Claudio, Bisacco, Daniel, Bischetti, Michelangelo, Boccalon, Luca, Bonanno, Paolo, Bonardelli, Stefano, Borioni, Raul, P Borrelli, Maria, Bozzani, Antonio, M Bracale, Umberto, Camparini, Stefano, Canciglia, Aldo, Canova, Francesco, Capoccia, Laura, Cappelli, Alessandro, Cappiello, Pierlugi, Carluccio, Chiara, Casalino, Alfonso, Casella, Francesco, Casilli, Giulia, Castagno, Claudio, Castelli, Patrizio, Castrucci, Tommaso, Cavallo, Matteo, Cavazzini, Carlo, Ceccanei, Gianluca, Cefalì, Pietro, Celoria, Gianni, Cevolani, Mauro, Chiappa, Roberto, Chisci, Emiliano, Comande, Carlo, Compagna, Rita, Cumino, Andrea, Cuozzo, Simone, Dalla Caneva, Patrizia, D'Alessio, Ilaria, D'Arrigo, Giuseppe, DE Caridi, Giovanni, DE Donato, Gianmarco, DE Donno, Gabriele, Desantis, Claudio, DE Santis, Francesco, DE Troia, Alessandro, Dezi, Tommaso, A Diaco, Domenico, DI Domenico, Rossella, DI Filippo, Michele, DI Girolamo, Alessia, P Dionisi, Carlo, Dinoto, Ettore, DI Stefano, Francesco, DI STEFANO, Lucia, D'Oria, Mario, Esposito, Andrea, Esposito, Davide, Ettore, Ludovica, F Fadda, Gian, Faggioli, Gianluca, T Fargion, Aaron, Fazzini, Stefano, Fermani, Nicoletta, Ferrante, Giulia, Ferrari, Mauro, Ferraro, Stafanio, Ferrer, Ciro, Ferretto, Luca, Ficarelli, Ilaria, Filippi, Federico, Fino, Gianluigi, Forliti, Enzo, Formiconi, Martina, Flora, Loris, Fresilli, Mauro, Frigatti, Paolo, Frigerio, Dalmazio, Froio, Alberto, Freyrie, Antonio, Furgiuele, Sergio, Gabrielli, Roberto, Gaggiano, Andrea, Galassi, Luca, Gallelli, Giuseppe, Gallitto, Enrico, Gallo, Francesco, Galzerano, Giuseppe, Gargiulo, Mauro, Garriboli, Luca, G Genadiev, Genadi, Gentile, Lucia, Giaquinta, Alessia, Gibello, Lorenzo, Grande, Raffaele, Grassi, Viviana, Ippoliti, Arnaldo, Irsara, Sandro, Kahlberg, Andrea, Konstantinos, Nikolakopoulos, LA Corte, Francesco, Lanza, Gaetano, Lauricella, Antonio, Lazzeri, Elisa, Lenti, Massimo, Leopardi, Marco, Lepidi, Sandro, Li Destri, Andrea, Locatelli, Federica, Lomazzi, Chiara, Lombardi, Francesco, Lorido, Antonio, Maggiore, Claudia, Mansour, Wassim, Marcucci, Vittorio, Mascia, Daniele, Massara, Mafalda, Mastrangelo, Giovanni, Margheritini, Costanza, Maritati, Gabriele, Martelli, Eugenio, Martinelli, Ombretta, Marzano, Antonio, Mauri, Francesca, Mazzacaro, Daniela, Melloni, Andrea, Mezzetti, Roberto, Michelagnoli, Stefano, Migliara, Bruno, Migliari, Mattia, Millarelli, Massimiliano, Misuraca, Maria, Modugno, Pietro, Moniaci, Diego, Montelione, Nunzio, Monti, Andrea, Monzio-Compagnoni, Nicola, Moro, Mario, Mortola, Lorenzo, Mozzetta, Gaddiel, Musilli, Aldo, Nano, Giovanni, Occhiuto, Mariateresa, M Oddi, Fabio, Orellana, Bernardo, Orlando, Paola, Orrico, Matteo, A Pacilè, Maria, Pagliariccio, Gabriele, Pallini, Cristina, Palmieri, Armando, Palughi, Martina, Panagrasso, Marco, Panzano, Claudia, Panzera, Chiara, Pascucci, Francesco, Pasqua, Rocco, Pasquetti, Leonardo, Pasqui, Eduardo, Pecchio, Alberto, Pecoraro, Felice, Peluttiero, Ilaria, F Pennetta, Federico, Perini, Paolo, Piazza, Michele, Pini, Rodolfo, Pipito, Narayana, Pranteda, Chiara, Praquin, Barbara, Pratesi, Carlo, F Porreca, Carlo, Pulli, Raffaele, Reina, Nicola, F Rinaldi, Luigi, Rizzo, Luigi, Romano, Elisa, Ronchey, Sonia, Ruggiero, Federica, Ruggiero, Massimo, Sallustro, Marianna, Saviane, Gianna, Sbarigia, Enrico, Scovazzi, Paolo, M Segramor, Vittorio, Sena, Giuseppe, Setacci, Carlo, Setacci, Francesco, E Setteducati, Carmen, M Settembrini, Alberto, Siani, Andrea, Sica, Simona, Speziale, Francesco, Squizzato, Francesco, Stella, Nazzareno, Stilo, Francesco, Sufali, Gemmi, Tanda, Elisabetta, Tinelli, Giovanni, Tomei, Francesca, Tosti, Filomena, Trimarchi, Santi, Troisi, Nicola, Tshomba, Yamume, Turchino, Davide, Turriziani, Valerio, Ucci, Alessandro, Veneto, Vincenzo, Veraldi, Gianfranco, Wiesel, Paola, Xodo, Andrea, Zacà, Sergio, Zaraca, Francesco, Zenunaj, Glaudiol, Sirignano, P, Piffaretti, G, Ceruti, S, Orso, M, Picozzi, M, Ricci, G, Sirignano, A, Taurino, M, Giancarlo Accarino, M, Accrocca, F, Alba, G, Alberti, A, Alberti, V, Allevi, S, Aloisi, F, Amato, B, Amico, A, Andreoli, F, Angiletta, D, Antico, A, Antico, L, Antonello, M, Baccellieri, D, Badalamenti, G, Bafile, G, Baldi, C, Barillà, C, Barillà, D, Bartoli, S, Basile, G, Battaglia, G, Battocchio, C, Belloni, A, Bellosta, R, Benevento, D, Bernardini, G, Bertagna, G, Bertoglio, L, Bianchini Massoni, C, Bisacco, D, Bischetti, M, Boccalon, L, Bonanno, P, Bonardelli, S, Borioni, R, P Borrelli, M, Bozzani, A, M Bracale, U, Camparini, S, Canciglia, A, Canova, F, Capoccia, L, Cappelli, A, Cappiello, P, Carluccio, C, Casalino, A, Casella, F, Casilli, G, Castagno, C, Castelli, P, Castrucci, T, Cavallo, M, Cavazzini, C, Ceccanei, G, Cefalì, P, Celoria, G, Cevolani, M, Chiappa, R, Chisci, E, Comande, C, Compagna, R, Cumino, A, Cuozzo, S, Dalla Caneva, P, D'Alessio, I, D'Arrigo, G, DE Caridi, G, DE Donato, G, DE Donno, G, Desantis, C, DE Santis, F, DE Troia, A, Dezi, T, A Diaco, D, DI Domenico, R, DI Filippo, M, DI Girolamo, A, P Dionisi, C, Dinoto, E, DI Stefano, F, DI STEFANO, L, D'Oria, M, Esposito, A, Esposito, D, Ettore, L, F Fadda, G, Faggioli, G, T Fargion, A, Fazzini, S, Fermani, N, Ferrante, G, Ferrari, M, Ferraro, S, Ferrer, C, Ferretto, L, Ficarelli, I, Filippi, F, Fino, G, Forliti, E, Formiconi, M, Flora, L, Fresilli, M, Frigatti, P, Frigerio, D, Froio, A, Freyrie, A, Furgiuele, S, Gabrielli, R, Gaggiano, A, Galassi, L, Gallelli, G, Gallitto, E, Gallo, F, Galzerano, G, Gargiulo, M, Garriboli, L, G Genadiev, G, Gentile, L, Giaquinta, A, Gibello, L, Grande, R, Grassi, V, Ippoliti, A, Irsara, S, Kahlberg, A, Konstantinos, N, LA Corte, F, Lanza, G, Lauricella, A, Lazzeri, E, Lenti, M, Leopardi, M, Lepidi, S, Li Destri, A, Locatelli, F, Lomazzi, C, Lombardi, F, Lorido, A, Maggiore, C, Mansour, W, Marcucci, V, Mascia, D, Massara, M, Mastrangelo, G, Margheritini, C, Maritati, G, Martelli, E, Martinelli, O, Marzano, A, Mauri, F, Mazzacaro, D, Melloni, A, Mezzetti, R, Michelagnoli, S, Migliara, B, Migliari, M, Millarelli, M, Misuraca, M, Modugno, P, Moniaci, D, Montelione, N, Monti, A, Monzio-Compagnoni, N, Moro, M, Mortola, L, Mozzetta, G, Musilli, A, Nano, G, Occhiuto, M, M Oddi, F, Orellana, B, Orlando, P, Orrico, M, A Pacilè, M, Pagliariccio, G, Pallini, C, Palmieri, A, Palughi, M, Panagrasso, M, Panzano, C, Panzera, C, Pascucci, F, Pasqua, R, Pasquetti, L, Pasqui, E, Pecchio, A, Pecoraro, F, Peluttiero, I, F Pennetta, F, Perini, P, Piazza, M, Pini, R, Pipito, N, Pranteda, C, Praquin, B, Pratesi, C, F Porreca, C, Pulli, R, Reina, N, F Rinaldi, L, Rizzo, L, Romano, E, Ronchey, S, Ruggiero, F, Ruggiero, M, Sallustro, M, Saviane, G, Sbarigia, E, Scovazzi, P, M Segramor, V, Sena, G, Setacci, C, Setacci, F, E Setteducati, C, M Settembrini, A, Siani, A, Sica, S, Speziale, F, Squizzato, F, Stella, N, Stilo, F, Sufali, G, Tanda, E, Tinelli, G, Tomei, F, Tosti, F, Trimarchi, S, Troisi, N, Tshomba, Y, Turchino, D, Turriziani, V, Ucci, A, Veneto, V, Veraldi, G, Wiesel, P, Xodo, A, Zacà, S, Zaraca, F, Zenunaj, G, SIRIGNANO, Pasqualino, PIFFARETTI, Gabriele, CERUTI, Silvia, ORSO, Massimiliano, PICOZZI, Mario, RICCI, Giovanna, SIRIGNANO, Ascanio, TAURINO, Maurizio, Giancarlo Accarino, Maurizio, Accrocca, Federico, Alba, Giuseppe, Alberti, Antonino, Alberti, Vittorio, Allevi, Sara, Aloisi, Francesco, Amato, Bruno, Amico, Alessio, Andreoli, Francesco, Angiletta, Domenico, Antico, Antonio, Antico, Lorenzo, Antonello, Michele, Baccellieri, Domenico, Badalamenti, Giovanni, Bafile, Gennaro, Baldi, Claudio, Barillà, Chiara, Barillà, David, Bartoli, Stefano, Basile, Giusi, Battaglia, Giuseppe, Battocchio, Cesare, Belloni, Ailin, Bellosta, Raffello, Benevento, Domenico, Bernardini, Giulia, Bertagna, Giulia, Bertoglio, Luca, Bianchini Massoni, Claudio, Bisacco, Daniel, Bischetti, Michelangelo, Boccalon, Luca, Bonanno, Paolo, Bonardelli, Stefano, Borioni, Raul, P Borrelli, Maria, Bozzani, Antonio, M Bracale, Umberto, Camparini, Stefano, Canciglia, Aldo, Canova, Francesco, Capoccia, Laura, Cappelli, Alessandro, Cappiello, Pierlugi, Carluccio, Chiara, Casalino, Alfonso, Casella, Francesco, Casilli, Giulia, Castagno, Claudio, Castelli, Patrizio, Castrucci, Tommaso, Cavallo, Matteo, Cavazzini, Carlo, Ceccanei, Gianluca, Cefalì, Pietro, Celoria, Gianni, Cevolani, Mauro, Chiappa, Roberto, Chisci, Emiliano, Comande, Carlo, Compagna, Rita, Cumino, Andrea, Cuozzo, Simone, Dalla Caneva, Patrizia, D'Alessio, Ilaria, D'Arrigo, Giuseppe, DE Caridi, Giovanni, DE Donato, Gianmarco, DE Donno, Gabriele, Desantis, Claudio, DE Santis, Francesco, DE Troia, Alessandro, Dezi, Tommaso, A Diaco, Domenico, DI Domenico, Rossella, DI Filippo, Michele, DI Girolamo, Alessia, P Dionisi, Carlo, Dinoto, Ettore, DI Stefano, Francesco, DI STEFANO, Lucia, D'Oria, Mario, Esposito, Andrea, Esposito, Davide, Ettore, Ludovica, F Fadda, Gian, Faggioli, Gianluca, T Fargion, Aaron, Fazzini, Stefano, Fermani, Nicoletta, Ferrante, Giulia, Ferrari, Mauro, Ferraro, Stafanio, Ferrer, Ciro, Ferretto, Luca, Ficarelli, Ilaria, Filippi, Federico, Fino, Gianluigi, Forliti, Enzo, Formiconi, Martina, Flora, Loris, Fresilli, Mauro, Frigatti, Paolo, Frigerio, Dalmazio, Froio, Alberto, Freyrie, Antonio, Furgiuele, Sergio, Gabrielli, Roberto, Gaggiano, Andrea, Galassi, Luca, Gallelli, Giuseppe, Gallitto, Enrico, Gallo, Francesco, Galzerano, Giuseppe, Gargiulo, Mauro, Garriboli, Luca, G Genadiev, Genadi, Gentile, Lucia, Giaquinta, Alessia, Gibello, Lorenzo, Grande, Raffaele, Grassi, Viviana, Ippoliti, Arnaldo, Irsara, Sandro, Kahlberg, Andrea, Konstantinos, Nikolakopoulos, LA Corte, Francesco, Lanza, Gaetano, Lauricella, Antonio, Lazzeri, Elisa, Lenti, Massimo, Leopardi, Marco, Lepidi, Sandro, Li Destri, Andrea, Locatelli, Federica, Lomazzi, Chiara, Lombardi, Francesco, Lorido, Antonio, Maggiore, Claudia, Mansour, Wassim, Marcucci, Vittorio, Mascia, Daniele, Massara, Mafalda, Mastrangelo, Giovanni, Margheritini, Costanza, Maritati, Gabriele, Martelli, Eugenio, Martinelli, Ombretta, Marzano, Antonio, Mauri, Francesca, Mazzacaro, Daniela, Melloni, Andrea, Mezzetti, Roberto, Michelagnoli, Stefano, Migliara, Bruno, Migliari, Mattia, Millarelli, Massimiliano, Misuraca, Maria, Modugno, Pietro, Moniaci, Diego, Montelione, Nunzio, Monti, Andrea, Monzio-Compagnoni, Nicola, Moro, Mario, Mortola, Lorenzo, Mozzetta, Gaddiel, Musilli, Aldo, Nano, Giovanni, Occhiuto, Mariateresa, M Oddi, Fabio, Orellana, Bernardo, Orlando, Paola, Orrico, Matteo, A Pacilè, Maria, Pagliariccio, Gabriele, Pallini, Cristina, Palmieri, Armando, Palughi, Martina, Panagrasso, Marco, Panzano, Claudia, Panzera, Chiara, Pascucci, Francesco, Pasqua, Rocco, Pasquetti, Leonardo, Pasqui, Eduardo, Pecchio, Alberto, Pecoraro, Felice, Peluttiero, Ilaria, F Pennetta, Federico, Perini, Paolo, Piazza, Michele, Pini, Rodolfo, Pipito, Narayana, Pranteda, Chiara, Praquin, Barbara, Pratesi, Carlo, F Porreca, Carlo, Pulli, Raffaele, Reina, Nicola, F Rinaldi, Luigi, Rizzo, Luigi, Romano, Elisa, Ronchey, Sonia, Ruggiero, Federica, Ruggiero, Massimo, Sallustro, Marianna, Saviane, Gianna, Sbarigia, Enrico, Scovazzi, Paolo, M Segramor, Vittorio, Sena, Giuseppe, Setacci, Carlo, Setacci, Francesco, E Setteducati, Carmen, M Settembrini, Alberto, Siani, Andrea, Sica, Simona, Speziale, Francesco, Squizzato, Francesco, Stella, Nazzareno, Stilo, Francesco, Sufali, Gemmi, Tanda, Elisabetta, Tinelli, Giovanni, Tomei, Francesca, Tosti, Filomena, Trimarchi, Santi, Troisi, Nicola, Tshomba, Yamume, Turchino, Davide, Turriziani, Valerio, Ucci, Alessandro, Veneto, Vincenzo, Veraldi, Gianfranco, Wiesel, Paola, Xodo, Andrea, Zacà, Sergio, Zaraca, Francesco, and Zenunaj, Glaudiol

Abstract

BACKGROUND: The SAfety and FEasibility of standard EVAR outside the instruction for use (SAFE-EVAR) Study was designed to define the attitude of Italian vascular surgeons towards the use of standard endovascular repair (EVAR) for infrarenal abdominal aortic aneurysm (AAA) outside the instruction for use (IFU) through a Delphi consensus endorsed by the Italian Society of Vascular and Endovascular Surgery (Società Italiana di Chirurgia Vascolare ed Endovascolare - SI CVE). METHODS : A questionnaire consisting of 26 statements was developed, validated by an 18-member Advisory Board, and then sent to 600 Italian vascular surgeons. The Delphi process was structured in three subsequent rounds which took place between April and June 2023. In the first two rounds, respondents could indicate one of the following five degrees of agreement: 1) strongly agree; 2) partially agree; 3) neither agree nor disagree; 4) partially disagree; 5) strongly disagree; while in the third round only three different choices were proposed: 1) agree; 2) neither agree nor disagree; 3) disagree. We considered the consensus reached when ≥70% of respondents agreed on one of the options. After the conclusion of each round, a report describing the percentage distribution of the answers was sent to all the participants. RESULTS: Two-hundred-forty-four (40.6%) Italian Vascular Surgeons agreed to participate the first round of the Delphi Consensus; the second and the third rounds of the Delphi collected 230 responders (94.3% of the first-round responders). Four statements (15.4%) reached a consensus in the first rounds. Among the 22 remaining statements, one more consensus (3.8%) was achieved in the second round. Finally, seven more statements (26.9%) reached a consensus in the simplified last round. Globally, a consensus was reached for almost half of the proposed statements (46.1%). CONCLUSIONS: The relatively low consensus rate obtained in this Delphi seems to confirm the discrepancy between Guideline

Published
2024

8. Multifactorial intestinal ischemia: a rare and undervalued diagnosis of abdominal pain.

Author

Morena, Annadora, Cirillo, Domenico, Natale, Raffaele, Nasti, Clelia, Torella, Tullia, Di Domenico, Rossella, Pasanisi, Fabrizio, and Santarpia, Lidia

Abstract

A 71-year-old woman was admitted to the hospital after consuming food due to acute malnutrition and abdominal pain. Reduced patency of all jejunoileal branches and the superior mesenteric artery was observed in the abdominal computed tomography scan. Abdominal angina was caused by atherosclerosis, the frequent use of triptans for recurrent migraines, the JAK2 mutation, and a high platelet count. The patient's complete parenteral nutrition was not spared, despite the development of a collateral circulation preventing fatal acute ischemia. [ABSTRACT FROM AUTHOR]

Published
2024
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13. Factors Affecting Patency of In Situ Saphenous Vein Bypass: Two Year Results from LIMBSAVE (Treatment of critical Limb Ischaemia with infragenicular Bypass adopting in situ SAphenous VEin technique) Registry

Author

Troisi, Nicola, primary, Adami, Daniele, additional, Michelagnoli, Stefano, additional, Berchiolli, Raffaella, additional, Accrocca, Federico, additional, Amico, Alessio, additional, Angelini, Andrea, additional, Arnuzzo, Luca, additional, Marchetti, Andrea Ascoli, additional, Attisani, Luca, additional, Bafile, Gennaro, additional, Baldino, Giuseppe, additional, Barbanti, Enrico, additional, Bartoli, Stefano, additional, Bellosta, Raffaello, additional, Benedetto, Filippo, additional, Borioni, Raoul, additional, Briolini, Franco, additional, Busoni, Cristina, additional, Camparini, Stefano, additional, Cappiello, Pierluigi, additional, Carbonari, Luciano, additional, Casella, Francesco, additional, Celoria, Giovanni, additional, Chiama, Andrea, additional, Chisci, Emiliano, additional, Civilini, Efrem, additional, Codispoti, Francesco, additional, Conti, Barbara, additional, Coppi, Giovanni, additional, De Blasis, Giovanni, additional, D’Elia, Marcello, additional, Di Domenico, Rossella, additional, Di Girolamo, Carla, additional, Ercolini, Leonardo, additional, Ferrari, Alessandra, additional, Ferrari, Mauro, additional, Forliti, Enzo, additional, Frigatti, Paolo, additional, Frigerio, Dalmazio, additional, Frosini, Pierfrancesco, additional, Garriboli, Luca, additional, Giordano, Antonio Nicola, additional, Guerrieri, Walter, additional, Jannello, Antonio, additional, Massara, Mafalda, additional, Merlo, Maurizio, additional, Mezzetti, Roberto, additional, Miccoli, Tommaso, additional, Milite, Domenico, additional, Mingazzini, Pietro, additional, Muncinelli, Marina, additional, Nano, Giovanni, additional, Natola, Marco, additional, Novali, Claudio, additional, Palasciano, Giancarlo, additional, Perkmann, Reinhold, additional, Persi, Federica, additional, Petruccelli, David, additional, Pinelli, Mauro, additional, Poletto, Giorgio, additional, Porta, Carla, additional, Pratesi, Carlo, additional, Pruner, Gianguido, additional, Ragazzi, Giovanni, additional, Righini, Paolo, additional, Salvini, Mauro, additional, Scovazzi, Paolo, additional, Setacci, Carlo, additional, Settembrini, Alberto Maria, additional, Siani, Andrea, additional, Silingardi, Roberto, additional, Silvestro, Antonino, additional, Talarico, Francesco, additional, Tolva, Valerio, additional, Trani, Antonio, additional, Trimarchi, Santi, additional, Tshomba, Yamume, additional, Vigliotti, Gennaro, additional, Viola, Daniela, additional, Volpe, Pietro, additional, and Zani, Federico, additional

Published
2022
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14. Comparison of long occlusive femoropopliteal de novo versus previous endovascularly treated lesions managed with in situ saphenous bypass

Author

Troisi, Nicola, primary, Michelagnoli, Stefano, additional, Adami, Daniele, additional, Berchiolli, Raffaella, additional, Accrocca, Federico, additional, Amico, Alessio, additional, Angelini, Andrea, additional, Arnuzzo, Luca, additional, Marchetti, Andrea Ascoli, additional, Attisani, Luca, additional, Bafile, Gennaro, additional, Baldino, Giuseppe, additional, Barbanti, Enrico, additional, Bartoli, Stefano, additional, Bellosta, Raffaello, additional, Benedetto, Filippo, additional, Borioni, Raoul, additional, Briolini, Franco, additional, Busoni, Cristina, additional, Camparini, Stefano, additional, Cappiello, Pierluigi, additional, Carbonari, Luciano, additional, Casella, Francesco, additional, Celoria, Giovanni, additional, Chiama, Andrea, additional, Chisci, Emiliano, additional, Civilini, Efrem, additional, Codispoti, Francesco, additional, Conti, Barbara, additional, Coppi, Giovanni, additional, De Blasis, Giovanni, additional, D’Elia, Marcello, additional, Di Domenico, Rossella, additional, Di Girolamo, Carla, additional, Ercolini, Leonardo, additional, Ferrari, Alessandra, additional, Ferrari, Mauro, additional, Forliti, Enzo, additional, Frigatti, Paolo, additional, Frigerio, Dalmazio, additional, Frosini, Pierfrancesco, additional, Garriboli, Luca, additional, Giordano, Antonio Nicola, additional, Guerrieri, Walter, additional, Jannello, Antonio, additional, Massara, Mafalda, additional, Merlo, Maurizio, additional, Mezzetti, Roberto, additional, Miccoli, Tommaso, additional, Milite, Domenico, additional, Mingazzini, Pietro, additional, Muncinelli, Marina, additional, Nano, Giovanni, additional, Natola, Marco, additional, Novali, Claudio, additional, Palasciano, Giancarlo, additional, Perkmann, Reinhold, additional, Persi, Federica, additional, Petruccelli, David, additional, Pinelli, Mauro, additional, Poletto, Giorgio, additional, Porta, Carla, additional, Pratesi, Carlo, additional, Pruner, Gianguido, additional, Ragazzi, Giovanni, additional, Righini, Paolo, additional, Salvini, Mauro, additional, Scovazzi, Paolo, additional, Setacci, Carlo, additional, Settembrini, Alberto Maria, additional, Siani, Andrea, additional, Silingardi, Roberto, additional, Silvestro, Antonino, additional, Talarico, Francesco, additional, Tolva, Valerio, additional, Trani, Antonio, additional, Trimarchi, Santi, additional, Tshomba, Yamume, additional, Vigliotti, Gennaro, additional, Viola, Daniela, additional, Volpe, Pietro, additional, and Zani, Federico, additional

Published
2022
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15. Comparison of long occlusive femoropopliteal de novo versus previous endovascularly treated lesions managed with in situ saphenous bypass

Author

Troisi, Nicola, Michelagnoli, Stefano, Adami, Daniele, Berchiolli, Raffaella, Accrocca, Federico, Amico, Alessio, Angelini, Andrea, Arnuzzo, Luca, Marchetti, Andrea Ascoli, Attisani, Luca, Bafile, Gennaro, Baldino, Giuseppe, Barbanti, Enrico, Bartoli, Stefano, Bellosta, Raffaello, Benedetto, Filippo, Borioni, Raoul, Briolini, Franco, Busoni, Cristina, Camparini, Stefano, Cappiello, Pierluigi, Carbonari, Luciano, Casella, Francesco, Celoria, Giovanni, Chiama, Andrea, Chisci, Emiliano, Civilini, Efrem, Codispoti, Francesco Alberto, Conti, Barbara, Coppi, Giovanni, De Blasis, Giovanni, D'Elia, Marcello, Di Domenico, Rossella, Di Girolamo, Carla, Ercolini, Leonardo, Ferrari, Alessandra, Ferrari, Mauro, Forliti, Enzo, Frigatti, Paolo, Frigerio, Dalmazio, Frosini, Pierfrancesco, Garriboli, Luca, Giordano, Antonio Nicola, Guerrieri, Walter, Jannello, Antonio, Massara, Mafalda, Merlo, Maurizio, Mezzetti, Roberto, Miccoli, Tommaso, Milite, Domenico, Mingazzini, Pietro, Muncinelli, Marina, Nano, Giovanni, Natola, Marco, Novali, Claudio, Palasciano, Giancarlo, Perkmann, Reinhold, Persi, Federica, Petruccelli, David, Pinelli, Mauro, Poletto, Giorgio, Porta, Carla, Pratesi, Carlo, Pruner, Gianguido, Ragazzi, Giovanni, Righini, Paolo, Salvini, Mauro, Scovazzi, Paolo, Setacci, Carlo, Settembrini, Alberto Maria, Siani, Andrea, Silingardi, Roberto, Silvestro, Antonino, Talarico, Francesco, Tolva, Valerio, Trani, Antonio, Trimarchi, Santi, Tshomba, Yamume, Vigliotti, Gennaro, Viola, Daniela, Volpe, Pietro, Zani, Federico, Codispoti, Francesco, Tshomba, Yamume (ORCID:0000-0001-7304-7553), Troisi, Nicola, Michelagnoli, Stefano, Adami, Daniele, Berchiolli, Raffaella, Accrocca, Federico, Amico, Alessio, Angelini, Andrea, Arnuzzo, Luca, Marchetti, Andrea Ascoli, Attisani, Luca, Bafile, Gennaro, Baldino, Giuseppe, Barbanti, Enrico, Bartoli, Stefano, Bellosta, Raffaello, Benedetto, Filippo, Borioni, Raoul, Briolini, Franco, Busoni, Cristina, Camparini, Stefano, Cappiello, Pierluigi, Carbonari, Luciano, Casella, Francesco, Celoria, Giovanni, Chiama, Andrea, Chisci, Emiliano, Civilini, Efrem, Codispoti, Francesco Alberto, Conti, Barbara, Coppi, Giovanni, De Blasis, Giovanni, D'Elia, Marcello, Di Domenico, Rossella, Di Girolamo, Carla, Ercolini, Leonardo, Ferrari, Alessandra, Ferrari, Mauro, Forliti, Enzo, Frigatti, Paolo, Frigerio, Dalmazio, Frosini, Pierfrancesco, Garriboli, Luca, Giordano, Antonio Nicola, Guerrieri, Walter, Jannello, Antonio, Massara, Mafalda, Merlo, Maurizio, Mezzetti, Roberto, Miccoli, Tommaso, Milite, Domenico, Mingazzini, Pietro, Muncinelli, Marina, Nano, Giovanni, Natola, Marco, Novali, Claudio, Palasciano, Giancarlo, Perkmann, Reinhold, Persi, Federica, Petruccelli, David, Pinelli, Mauro, Poletto, Giorgio, Porta, Carla, Pratesi, Carlo, Pruner, Gianguido, Ragazzi, Giovanni, Righini, Paolo, Salvini, Mauro, Scovazzi, Paolo, Setacci, Carlo, Settembrini, Alberto Maria, Siani, Andrea, Silingardi, Roberto, Silvestro, Antonino, Talarico, Francesco, Tolva, Valerio, Trani, Antonio, Trimarchi, Santi, Tshomba, Yamume, Vigliotti, Gennaro, Viola, Daniela, Volpe, Pietro, Zani, Federico, Codispoti, Francesco, and Tshomba, Yamume (ORCID:0000-0001-7304-7553)

Abstract

Background: The aim of this study was to compare the 2-year outcomes of de novo versus postendovascular lesion treatment of femoropopliteal occlusions included in a national, multicenter, observational, prospective registry based on the treatment of critical Limb-threatening IschaeMia with infragenicular Bypass adopting in situ SAphenous VEin technique (LIMBSAVE) registry.Methods: From January 2018 to December 2019, 541 patients from43 centers have been enrolled in the LIMBSAVE registry. Of these patients, 460 were included in the present study: 341 (74.1%) with de novo lesions (DN group) and 119 (25.9%) with postendovascular treatment lesions (PE group). Initial outcome measures were assessed at 30 days after treatment. Furthermore, at the 2-year follow-up, the estimated outcomes of primary patency, primary-assisted patency, secondary patency, and limb salvage were analyzed with Kaplan-Meier curves and compared between groups with the log-rank test.Results: Both groups were homogeneous in terms of demographic data, preoperative risk factors, and clinical presentation. However, compared with DN group, more patients in PE group had a great saphenous vein diameter of less than 3 mm (11.1% vs 21%; P = .007). Intraoperatively, both groups showed similar distal anastomosis sites: below-the-knee popliteal artery (63% DN group, 66.4% PE group) and tibial vessel (37% DN group, 33.6% PE group) (P = .3). The overall mean duration of follow-up was 11.6 months (range, 1-24 months). At the 2-year follow-up, there were no differences between the two groups in terms of primary patency (66.3% DN group vs 74.1% PE group; P = .9), primary-assisted patency (78.2% DN group vs 79.5% PE group; P = .2), secondary patency (85.1% DN group vs 91.4% PE group; P = .2), and limb salvage (95.2% DN group vs 95.1% PE group; P = .9).Conclusions: The LIMBSAVE registry did not show a worsening of overall patency and limb salvages rates at the 2-year follow-up in patients undergoing in situ saphenous

Published
2022

16. sj-doc-1-jet-10.1177_15266028211032954 ��� Supplemental material for Hybrid Surgical Approach to a Giant Post-Coarctation Aortic Aneurysm

Author

Di Domenico, Rossella, Fargion, Aaron Thomas, Speziali, Sara, Petroni, Rachele, Villani, Flavio, Esposito, Davide, and Pratesi, Carlo

Subjects
FOS: Clinical medicine, Cardiology, Medicine, 110323 Surgery
Abstract

Supplemental material, sj-doc-1-jet-10.1177_15266028211032954 for Hybrid Surgical Approach to a Giant Post-Coarctation Aortic Aneurysm by Rossella Di Domenico, Aaron Thomas Fargion, Sara Speziali, Rachele Petroni, Flavio Villani, Davide Esposito and Carlo Pratesi in Journal of Endovascular Therapy

Published
2022
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21. Preliminary six-month outcomes of LIMBSAVE (treatment of critical Limb IscheMia with infragenicular Bypass adopting in situ SAphenous VEin technique) registry

Author

Troisi, Nicola, Blasis, Giovanni De, Salvini, Mauro, Michelagnoli, Stefano, Setacci, Carlo, LIMBSAVE registry Collaborative, Group, Accrocca, Federico, Adami, Daniele, Angelini, Andrea, Arnuzzo, Luca, Ascoli Marchetti, Andrea, Attisani, Luca, Bafile, Gennaro, Baldino, Giuseppe, Barbanti, Enrico, Bartoli, Stefano, Bellosta, Raffaello, Benedetto, Filippo, Borioni, Raoul, Briolini, Franco, Busoni, Cristina, Camparini, Stefano, Cappiello, Pierluigi, Carbonari, Luciano, Casella, Francesco, Celoria, Giovanni, Chisci, Emiliano, Civilini, Efrem, Codispoti, Francesco Alberto, Conti, Barbara, Coppi, Giovanni, D’Amico, Alessio, De Blasis, Giovanni, D’Elia, Marcello, Di Domenico, Rossella, Di Girolamo, Carla, Ercolini, Leonardo, Ferrari, Alessandra, Ferrari, Mauro, Forliti, Enzo, Frigatti, Paolo, Frigerio, Dalmazio, Frosini, Pierfrancesco, Garriboli, Luca, Nicola Giordano, Antonio, Guerrieri, Walter, Jannello, Antonio, Massara, Mafalda, Merlo, Maurizio, Mezzetti, Roberto, Miccoli, Tommaso, Milite, Domenico, Mingazzini, Pietro, Muncinelli, Marina, Nano, Giovanni, Natola, Marco, Novali, Claudio, Palasciano, Giancarlo, Perkmann, Reinhold, Persi, Federica, Petruccelli, David, Pinelli, Mauro, Poletto, Giorgio, Porta, Carla, Pratesi, Carlo, Pruner, Gianguido, Ragazzi, Giovanni, Righini, Paolo, Scovazzi, Paolo, Maria Settembrini, Alberto, Siani, Andrea, Silingardi, Roberto, Silvestro, Antonino, Talarico, Francesco, Tolva, Valerio, Trani, Antonio, Trimarchi, Santi, Tshomba, Yamume, Vigliotti, Gennaro, Viola, Daniela, Volpe, Pietro, Zani, Federico, Codispoti, Francesco, Tshomba, Yamume (ORCID:0000-0001-7304-7553), Troisi, Nicola, Blasis, Giovanni De, Salvini, Mauro, Michelagnoli, Stefano, Setacci, Carlo, LIMBSAVE registry Collaborative, Group, Accrocca, Federico, Adami, Daniele, Angelini, Andrea, Arnuzzo, Luca, Ascoli Marchetti, Andrea, Attisani, Luca, Bafile, Gennaro, Baldino, Giuseppe, Barbanti, Enrico, Bartoli, Stefano, Bellosta, Raffaello, Benedetto, Filippo, Borioni, Raoul, Briolini, Franco, Busoni, Cristina, Camparini, Stefano, Cappiello, Pierluigi, Carbonari, Luciano, Casella, Francesco, Celoria, Giovanni, Chisci, Emiliano, Civilini, Efrem, Codispoti, Francesco Alberto, Conti, Barbara, Coppi, Giovanni, D’Amico, Alessio, De Blasis, Giovanni, D’Elia, Marcello, Di Domenico, Rossella, Di Girolamo, Carla, Ercolini, Leonardo, Ferrari, Alessandra, Ferrari, Mauro, Forliti, Enzo, Frigatti, Paolo, Frigerio, Dalmazio, Frosini, Pierfrancesco, Garriboli, Luca, Nicola Giordano, Antonio, Guerrieri, Walter, Jannello, Antonio, Massara, Mafalda, Merlo, Maurizio, Mezzetti, Roberto, Miccoli, Tommaso, Milite, Domenico, Mingazzini, Pietro, Muncinelli, Marina, Nano, Giovanni, Natola, Marco, Novali, Claudio, Palasciano, Giancarlo, Perkmann, Reinhold, Persi, Federica, Petruccelli, David, Pinelli, Mauro, Poletto, Giorgio, Porta, Carla, Pratesi, Carlo, Pruner, Gianguido, Ragazzi, Giovanni, Righini, Paolo, Scovazzi, Paolo, Maria Settembrini, Alberto, Siani, Andrea, Silingardi, Roberto, Silvestro, Antonino, Talarico, Francesco, Tolva, Valerio, Trani, Antonio, Trimarchi, Santi, Tshomba, Yamume, Vigliotti, Gennaro, Viola, Daniela, Volpe, Pietro, Zani, Federico, Codispoti, Francesco, and Tshomba, Yamume (ORCID:0000-0001-7304-7553)

Abstract

ObjectivesGuidelines recommend open bypass surgery for long occlusions of infrainguinal arteries. In situ saphenous vein bypass is a standardized technique. The aim of this study was to report preliminary six-month outcomes of a national, multicenter, observational, prospective registry based on the examination of treatment of critical Limb IscheMia with infragenicular Bypass adopting the in situ SAphenous VEin technique (LIMBSAVE).MethodsFrom January 2018 until October 2019, 428 patients from 41 centers were enrolled in the LIMBSAVE registry. Data were prospectively collected in a dedicated database, including demographics, preoperative risk factors, clinical and diagnostic preoperative assessments, intraoperative measures (including safety and effectiveness of the valvulotome during the surgical procedures), and 30-day follow-up data. Furthermore, estimated six-month outcomes according to Kaplan-Meier curves in terms of primary patency, primary assisted patency, secondary patency, and limb salvage were evaluated.ResultsPatients were predominantly male (n = 332, 77.6%) with a mean age of 73.3 years (range 39-95). Technical success, defined as bypass pulse after use of the valvulotome, was obtained in all cases. The proximal anastomosis could be reached by the valvulotome in all cases. The mean number of valvulotome uses was 2.5 (range 1-5). No vein perforation was reported. In nine cases (2.1%), a vein lesion with intramural hemorrhage occurred. The mean length of hospital stay was 11.1 days (range 1-60). At 30-day follow-up, the overall bypass patency rate was 97.4%, and the rate of open or endo reinterventions for failing bypass was 5.4%. At six-month follow-up, the estimated primary patency, primary assisted patency, secondary patency, and limb salvage were 78.1%, 86.2%, 92.1%, and 94.7%, respectively.ConclusionsPreliminary intraprocedural outcomes of the LIMBSAVE registry show that the in situ technique with the valvulotome is safe and effective in disrupting v

Published
2021

30. Modulation of mirror neurons' visual discharge in the monkey ventral premotor cortex (F5) in relation to the social context

Author

Di Domenico, Rossella

Subjects
neuroscience, monkey, mirror neurons, ventral premotor cortex, M-PSI/02
Abstract

Several studies show that mirror neurons' discharge in the monkey ventral premotor cortex and in the inferior parietal lobule is modulated by the action's goal and by the context in which the action has been executed (Fogassi et al., 2005; Bonini et al. 2009). In this study, we investigated how the social context can influence the modulation of visual mirror neurons' discharge in the monkey ventral premotor cortex (F5). In particular, we investigated if contextual information (such as the presence of a container), which requires a passive observation of the action, and social cues (such as the motor interaction between the observer and the executer), which requires the execution of an action in coordination with the observed agent, can affect differently the activity of mirror neurons' visual discharge in F5 area. We carried out electrophysiological recordings in the ventral premotor cortex of two macaques (Macaca mulatta), with a sixteen channels multielectrode. The neural activity was recorded in the visual task (VT) and in the motor task (MT) to demonstrate the presence of mirror response. The visual task was made under 4 conditions in which the monkey observed an experimenter grasping an object followed by one out of four possible action goal: 1. Container (grasping the object followed by placing it into a container), 2. Hand (grasping to place it into another experimenter's hand), 3. Monkey (grasping to place it into the monkey's hand; in this condition the monkey had to prepare and perform a grasping action), 4. Mouth (grasping the object in order to eat it). We find that the spikes frequency was significantly lower in the Monkey condition compared to the other 3 conditions. Interestingly, the spikes frequency and the time (between the contact of the experimenter's hand with the target and the release of the monkey's hand by her handle) were negatively correlated suggesting that the observation of an action which leads to an interaction with the observer attenuate the visual response of MN in the ventral premotor cortex. Diverse evidenze dimostrano che la scarica dei neuroni specchio della corteccia premotoria ventrale e del lobulo parietale inferiore è modulata dallo scopo finale di un'azione e dal contesto in cui l'azione viene eseguita (Fogassi et al. 2005; Bonini et al. 2009). In questo studio ci siamo proposti di indagare come il contesto sociale possa influire sulla modulazione della scarica visiva dei neuroni mirror della corteccia premotoria ventrale (F5). In particolare, ci siamo proposti di verificare se informazioni di natura contestuale (come la presenza di un contenitore o di un'interazione tra due individui), che richiedono solo un'osservazione passiva, ed informazioni di natura sociale che però sono seguiti da un'interazione con l'agente (osservazione attiva) e quindi richiedono una preparazione motoria da parte dell'osservatore, abbiano un impatto diverso nella modulazione della scarica visiva dei neuroni mirror di F5. Abbiamo condotto lo studio su due scimmie, del genere Macaca mulatta, in registrazione intracorticale extracellulare, con un multielettrodo da 16 canali. L'area di registrazione è stata la corteccia premotoria ventrale (area F5). L'attività neuronale veniva acquisita durante un compito visivo (CV) ed un compito motorio (CM), al fine di verificare se le risposte ottenute fossero di tipo “mirror”. Il compito visivo (CV) prevedeva 4 condizioni: Container (afferrare per piazzare in un contenitore), Hand (afferrare per piazzare nella mano di un altro sperimentatore), Monkey (afferrare per piazzare nella mano della scimmia), Mouth (afferrare per portare alla bocca). Abbiamo rilevato che la frequenza di scarica delle risposte visive dei neuroni mirror della premotoria ventrale, è significativamente inferiore nella condizione Monkey, rispetto alle altre condizioni. Inoltre, la frequenza di scarica tende a diminuire in relazione all'aumento del tempo intercorso tra il contatto della mano dello sperimentatore con l'oggetto target e il rilascio della mano della scimmia dal punto di partenza, mostrando quindi una correlazione di tipo negativo. Questi risultati suggeriscono che l'osservazione di un azione che richiede una successiva azione coordinata da parte dell'osservatore con l'agente osservato, produce un'attenuazione della scarica visiva dei neuroni specchio nella corteccia premotoria ventrale.

Published
2015

31. Early and Midterm Outcomes of Endovascular Aneurysm Repair With Zenith Alpha Abdominal Stent-Graft: Results From a Multicenter Retrospective Tuscany Registry

Author

Troisi, Nicola, Pulli, Raffaele, Donato, Gianmarco de, Adami, Daniele, Bertagna, Giulia, Michelagnoli, Stefano, Berchiolli, Raffaella, Canovaro, Francesco, Torri, Lorenzo, Pratesi, Carlo, Fargion, Aaron, Speziali, Sara, Di Domenico, Rossella, Petroni, Rachele, Palasciano, Giancarlo, Pasqui, Edoardo, Galzerano, Giuseppe, Molino, Cecilia, Giuseppe, Anzaldi Manfredi, Invernizzi, Claudio, Loschiavo, Vincenzo, Chisci, Emiliano, Caneva, Patrizia Dalla, Ercolini, Leonardo, Lazzeri, Elisa, Filippi, Federico, and Panzano, Claudia

Abstract

Purpose: Zenith Alpha Abdominal (Cook Medical, Bloomington, IN, USA) is one of the new-generation low-profile stent-grafts with demonstrated satisfactory early and midterm clinical outcomes for endovascular treatment of abdominal aortic aneurysms (AAAs). The aim was to evaluate early and midterm results of this device in the framework of a multicenter regional retrospective registry, with the analysis of morphological factors affecting outcomes, including different limb configurations.Materials and methods: Between January 2016 and November 2021, 202 patients with AAA underwent elective endovascular aneurysm repair (EVAR) with implantation of a Zenith Alpha Abdominal in 7 centers. Early (30 day) outcomes in terms of technical and clinical success were assessed. Estimated 5 year outcomes were evaluated in terms of survival, freedom from type I/III endoleak, freedom from surgical conversion, freedom from limb graft occlusion, freedom from any device-related reintervention, and graft infection evaluation by life-table analysis (Kaplan–Meier test). A comparative analysis between different limb configurations (Zenith Spiral Z AAA iliac legs, codes ZISL vs ZSLE) was performed in terms of limb graft occlusion.Results: The 30 day technical and clinical success rates were 97.5% and 99.5%, respectively. Median follow-up period was 25.5 months (interquartile range [IQR]: 12–43.25). The 5 year survival rate was 73.6%. The estimated 5 year outcomes in terms of freedom from type I/III endoleak, freedom from surgical conversion, freedom from limb graft occlusion, freedom from any device-related reintervention, and freedom from graft infection were 88.6% (95% CI [confidence interval]: 83.4%–93.1%), 95.8% (95% CI: 92.7%–97.1%), 93.6% (95% CI: 90.2%–96.8%), 87% (95% CI: 83.3%–91.6%), and 97.7% (95% CI: 95.1%–98.9%), respectively. About limb configuration, no differences were found in terms of 5 year freedom from limb graft occlusion (ZSLE 93.4% [95% CI: 89.8%–95.5%] vs ZISL 94.3% [95% CI: 90.1%–95.9%], p=0.342; log-rank 0.903).Conclusion: Zenith Alpha Abdominal in elective EVAR offered satisfactory early and 5 year outcomes with low complication rates. Limb graft occlusion continued to be an issue. Limb configuration did not affect outcomes.Clinical Impact The authors describe satisfactory early and 5 year outcomes of Zenith Alpha Abdominal in elective endovascular aortic repair in the framework of a multicenter regional retrospective registry. At 5 years freedom from type I endoleak was 88.6%, and rate of endograft infections and conversions to open repair were very low. in the present study. Hot topic about about Zenith stent-graft still remains the limb graft occlusion with a 30-day overall rate of 2%, and estimated 5-year freedom from limb graft occlusion of 93.6%. Limb graft configuration did not affect limb graft occlusion rate. A standardized protocol including iliac stenting should be adopted to reduce kimb graft occlusion.

Published
2024
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32. Deconstruction of farm machine-related safety interventions: a systematic review and narrative synthesis.

Author

Surendran A, McSharry J, Di Domenico R, Meredith D, Meade O, Malone S, and O'Hora D

Abstract

Introduction: Agricultural workplaces have a high number of incidents and fatalities, with the majority occurring from machinery use. Farmers' behaviour plays a critical role in maintaining safety, as improper or unsafe practices often lead to injuries and fatalities. This review categorises interventions targeting farm machine safety, examining both the behaviour change techniques (BCTs) used and their reported outcomes to understand how the techniques influence safety practices and outcomes on farms., Methods: The systematic review is reported in accordance with the Preferred reporting items for systematic reviews and meta-analysis guidelines. Seven electronic databases were searched for relevant studies published before June 2024, and the quality of included studies was assessed using Cochrane risk of bias assessment tools. Analysis of intervention behavioural components was guided by the behaviour change wheel framework and BCT taxonomy (v1). The findings were synthesised using a narrative review., Results: Nine studies were included and a total of 21 BCTs were identified. The most frequently coded BCTs were 4.1 (instruction on how to perform the behaviour), 10.8 (incentive [outcome]), and 16.3 (vicarious consequences) (each n = 6). Reported outcomes included reductions in injury rates, improved adoption of safety devices, implementation of safety measures, and positive shifts in safety norms and perceptions. However, due to variations in intervention design and reporting, assessing the direct impact of specific BCTs on these outcomes proved challenging., Discussion: The use of BCT taxonomy provided a common language for describing intervention components and enabled the standardisation of intervention content analysis. While patterns were observed regarding the commonly used BCTs, their implementation and outcomes, the heterogeneity and limited details provided by studies limited our ability to discern their effectiveness. Providing (i) greater transparency in reporting active intervention components and (ii) clearer connections between components and specific outcomes, will enable enhanced comparisons of future studies, and facilitate a greater understanding of how to support safe machine-related behaviours on farms., (© The Author(s) 2025. Published by Oxford University Press on behalf of the British Occupational Hygiene Society.)

Published
2025
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33. Protein-based tissue adhesive reduces time to haemostasis in peripheral vascular surgery.

Author

Troisi N, Marconi M, Michelagnoli S, Dalla Caneva P, Frosini P, Di Domenico R, Pratesi C, and Berchiolli R

Abstract

Objectives: The aim of this study was to evaluate the effectiveness of protein-based tissue adhesive (Bioglue ® ) in reducing time to haemostasis in patients undergoing peripheral vascular surgery., Methods: From January to December 2021, 100 consecutive patients from 4 centres have been treated with open peripheral vascular surgery including upper and lower limb interventions. Patients have been allocated in each centre into control with no use of Bioglue ® ( Group no-Bio , 50 patients) or use of Bioglue ® ( Group Bio , 50 patients) by a block randomization method 10:10 until the required sample size was reached. Perioperative parameters including time to haemostasis, number of adjunctive stitches, and in-hospital bleeding have been analysed and compared in the two groups by means of mean independent-samples t T -test and Gehan-Breslow-Wilcoxon test., Results: Both groups were homogeneous in terms of demographic data, preoperative risk factors, and preoperative medical therapy except for a higher percentage of active smokers in Group Bio (52% vs. 24%, p = 0.004). Femoral endarterectomy was most common in Group Bio (44% vs. 24%, p = 0.03), whilst the percentage of lower limb vein bypasses was higher in Group no-Bio (50% vs. 36%, p = 0.03). Bovine pericardium was the preferred material in Group Bio (20 cases, 40%), whilst autologous vein is mostly used in Group no-Bio (26 cases, 52%) ( p = 0.01). Time to haemostasis was faster in Group Bio (4.4 vs. 9.6 minutes, p < 0.001). The need for adjunctive stitches was higher in Group no-Bio (8 cases, 16%, Group Bio vs. 25 cases, 50%, Group no-Bio ; p < 0.001). The overall rate of in-hospital bleeding, including those requiring reintervention, was not different between the two groups (9 cases, 18%, Group Bio vs. 7 cases, 14%, Group no-Bio ; p = 0.39)., Conclusions: The protein-based tissue adhesive Bioglue ® reduced time to haemostasis and need for adjunctive stitches in peripheral vascular surgery. However, it did not affect the overall rate of perioperative bleedings. Further studies with larger sample sizes are needed to validate these outcomes., Competing Interests: Declaration of conflicting interestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Published
2024
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34. Early and long-term results of surgical treatment of popliteal artery aneurysms using a heparin-bonded expanded polytetrafluorethilene graft.

Author

Speziali S, Fargion AT, Giacomelli E, Esposito D, DI Domenico R, DE Blasis S, Piffaretti G, Pratesi C, Dorigo W, and Pulli R

Subjects
Humans, Heparin adverse effects, Blood Vessel Prosthesis, Retrospective Studies, Cohort Studies, Treatment Outcome, Vascular Patency, Popliteal Artery diagnostic imaging, Popliteal Artery surgery, Popliteal Artery Aneurysm, Blood Vessel Prosthesis Implantation adverse effects, Aneurysm diagnostic imaging, Aneurysm surgery
Abstract

Background: The aim of the present study was to assess early and long-term results of open surgical interventions for popliteal artery aneurysms (PAAs) with the use of heparin-bonded expanded polytetrafluorethylene (HePTFE) in a single center, retrospective, non-comparative cohort study., Methods: A retrospective analysis of a prospectively maintained dataset, including 207 open interventions for PAAs between 2002 and 2022, was performed and 170 procedures carried on with the use of a HePTFE graft were found. Perioperative results were analyzed in terms of mortality, graft thrombosis and amputation rates. Follow-up results were analyzed in terms of survival, primary and secondary patency, freedom from amputation, freedom from reintervention with life-table analysis and Kaplan Meier curves. Follow-up results were considered as primary outcomes, whereas perioperative results were considered as secondary outcomes., Results: In 82 interventions (48%) the PAA was asymptomatic. In 140 cases a medial approach was used, while in 30 cases a posterior approach was preferred. The level of the distal anastomosis was the p3 tract of the popliteal artery in 89% of the cases. One perioperative death occurred; early thromboses occurred in eight cases and the overall perioperative amputation rate was 2.8%. The median duration of follow-up was 48 months (range 1-251). Estimated survival rate at 10 years was 55% (standard error, SE, 0.065). The 10-year rates of primary and secondary patency and freedom from amputation were 40.8% (SE 0.06), 47.6% (SE 0.065) and 93.4% (SE 0.04), respectively. The estimated freedom from reintervention rate at 10 years was 57% (SE 0.05)., Conclusions: The results of this large monocentric experience showed that open surgical repair of PAAs with HePTFE is a safe procedure, with low rates of perioperative complications, and excellent results in the long-term setting.

Published
2023
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35. Stability of the aneurysmatic sac post-EVAR could no longer be a reliable criterion of healing.

Author

Esposito D, Fargion AT, Dorigo W, Melani A, Capone A, DI Domenico R, Villani F, Speziali S, and Pratesi C

Subjects
Endoleak surgery, Humans, Retrospective Studies, Risk Factors, Time Factors, Treatment Outcome, Aortic Aneurysm, Abdominal diagnostic imaging, Aortic Aneurysm, Abdominal surgery, Blood Vessel Prosthesis Implantation adverse effects, Endovascular Procedures adverse effects
Abstract

Background: Evaluation of the impact of aneurysm sac behavior in terms of either stability or shrinkage after endovascular aneurysm repair (EVAR) on long-term clinical outcomes., Methods: A retrospective study was conducted on 1483 consecutive patients who underwent EVAR from 1999 to 2021 at our institution. 1037 patients met inclusion criteria (1037/1483, 69.9%): abdominal aortic or aorto-iliac aneurysm, elective surgery, follow-up (FU) ≥12 months. Patients who had sac stability (330/1037, 31.8%) and patients who demonstrated sac shrinkage (542/1037, 52.2%) at FU were compared; patients who presented sac increase at FU were excluded (165/1037, 16%)., Primary Endpoints: rupture rates, need for surgical conversion, and long-term aneurysm-related mortality. Secondary endpoints: all type endoleak rates and long-term reintervention rates., Results: Mean FU was 61.2 months (IQ 26-85.7 months). In terms of comorbidities, the group of patients with stable sac showed greater association with polidistrectual atherosclerotic manifestations. Estimated 12-year survival was 42.9% in the stable sac group and 65% in the shrinked group (P<0.001), although there were no significant differences in terms of freedom from aneurysm-related death (97.3% vs. 95.4% estimated at 12 years, P=0.493). Patients with sac stability had higher rates of rupture (2.1% vs. 0.6%, P=0.035) and surgical conversion (2.1% vs. 0.6%, P=0.035). The stable sac group had significantly higher rates of all type endoleak during FU (45.8% vs. 24%, P<0.001). Estimated 12-year freedom from reintervention rates were 56.2% and 83.9% respectively (P<0.001)., Conclusions: After more than 20 years of EVAR experience it is probably time to reconsider the procedure clinical success parameters as a patient with a stable sac cannot be considered healed.

Published
2022
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