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Bu çalışma sağlık hizmetleri bağlamında sağlık sunucularını konu edinmektedir. Araştırma, sağlık sunucularının iyileşen hasta sayısı üzerindeki etkilerini belirlemeyi amaçlamaktadır. Araştırmanın evrenini OECD ülkeleri oluşturmaktadır. Araştırmanın örneklemi ise, araştırma değişkenlerine ilişkin verileri tam olan 9 OECD ülkesinden (Kanada, İsrail, Slovenya, Türkiye, Fransa, Almanya, Slovak Cumhuriyeti, Lüksemburg, Hollanda) ibarettir. Araştırmanın bağımsız değişkenleri hekim sayısı, hemşire sayısı ve ebe sayısıdır. Bağımlı değişken ise, iyileşen hasta sayısıdır. Araştırma verileri 2003 ile 2019 yılları arasında yer almaktadır. Elde edilen veriler, LM, CDlm , CD, LMadj, CADF birim kök, eşbütünleşme, Common Correlated Effect (CCE) ve Augmented Mean Group Estimator (AMG) ile Emirmahmutoğlu ve Köse panel nedensellik testleri aracılığıyla analiz edilmiştir. Araştırmanın sonuçlarına göre, hekim sayısı iyileşen hasta sayısını artırırken, hemşire sayısı iyileşen hasta sayısını azaltmaktadır. Ayrıca iyileşen hasta sayısının hekim, hemşire ve ebe sayılarının bir nedeni olduğu tespit edilmiştir. Bununla birlikte hekim, hemşire ve ebe sayılarının da iyileşen hasta sayısının bir nedeni olduğu sonucuna ulaşılmıştır.

Bu araştırmanın amacı, sağlık harcamalarında yapılmış akademik çalışmaları bibliyometri yöntemiyle inceleyerek araştırmacılara konuyla ilgili detaylı bilgiler sunmaktır. Araştırma verileri, 1970-2021 yılları arasında yer almaktadır. Çalışmanın verileri Web of Science veri tabanından elde edilmiştir. Araştırma kapsamında yer alan 1.983 çalışma, görsel haritalama tekniği kullanılarak bibliyometrik açıdan analiz edilmiştir. Çalışmanın verileri, üç dönemde incelenmiştir. Çalışmanın verileri, yazarlar, atıflar, dergiler, yıllar ve terimler bakımından değerlendirilmiştir. Ayrıca araştırmanın verileri, SciMAT programı kullanılarak araştırma amaçları doğrultusunda test edilmiştir. Araştırmanın sonuçlarına göre sağlık giderleri, harcama, nüfus, ülke, bakıcı, kardiyovasküler hastalık, aşırı harcamalar ve eğilim olmak üzere sekiz ana küme belirlenmiştir. SciMAT yazılımı ile tespit edilen kümelerin ağ yapıları, boylamsal ve stratejik diyagramlar aracılığıyla incelenmiştir. Kümelerin dönemlere göre dağılımının incelenmesi, ilerde yapılacak çalışmalar açısından yol gösterici olacaktır. Ayrıca çalışma sonuçlarının, pandemi nedeniyle son yıllarda artış gösteren sağlık harcamaları konusunda bilgi edinilmesine olanak sağlayacağı düşünülmektedir.

Bu çalışma sağlık hizmetleri bağlamında sağlık personellerini konu edinmektedir. Araştırma, sağlık personellerinin iyileşen hasta sayısı üzerindeki etkilerini belirlemeyi amaçlamaktadır. Araştırmada evren belirlenmemiş, çalışmada yer alan modele ilişkin verileri tam olan ülkeler üzerinde çalışılmıştır. Bu anlamda araştırma değişkenlerine ilişkin verileri tam olan 9 OECD ülkesi (Kanada, İsrail, Slovenya, Türkiye, Fransa, Almanya, Slovak Cumhuriyeti, Lüksemburg, Hollanda) çalışmada değerlendirilmiştir. Araştırmada test edilecek model, literatür göz önünde bulundurularak bundan sonraki çalışmalara yol gösterici olacağı düşünülerek tasarlanmıştır. Buna göre araştırmanın bağımsız değişkenleri hekim sayısı, hemşire sayısı ve ebe sayısıdır. Bağımlı değişken ise, iyileşen hasta sayısıdır. Araştırma verileri 2003 ile 2019 yılları arasında yer almaktadır. Elde edilen veriler, LM (1980), CDlm (2004), CD (2004), LMadj (2008) yatay kesit bağımlılığı testleri, CADF birim kök testi (2007), Westerlund ve Edgerton (2007) LM Bootstrap eşbütünleşme testi, CCE (2006) ve AMG (2010), Emirmahmutoğlu ve Köse (2011) panel nedensellik testleri aracılığıyla analiz edilmiştir. Araştırmanın sonuçlarına göre, panelin genelinde hekim sayısı iyileşen hasta sayısını artırırken, hemşire sayısı iyileşen hasta sayısını azaltmaktadır. Ayrıca Emirmahmutoğlu ve Köse (2011) nedensellik sonuçlarına göre iyileşen hasta sayısı ile hekim, hemşire ve ebe sayıları arasında karşılıklı nedensellik ilişkisi bulunduğu tespit edilmiştir.

Bu çalışma, hemşirelerde örgütsel sessizlik problemini incelemeyi amaçlamaktadır. Araştırma örgütsel sessizlik kavramını konu edinmesinin yanı sıra sağlık kurumlarında örgütsel sessizlik konusuna odaklanmaktadır. Araştırmanın evrenini bir eğitim ve araştırma hastanesindeki hemşireler oluşturmaktadır. Araştırmanın örneklemi ise ilgili kurumda görevli olan 306 hemşireden ibarettir. Bu çalıma için, Fırat Üniversitesi, Sosyal ve Beşeri Bilimler Araştırmaları Etik Kurulu’nda 15/01/2019 tarih ve 306042 sayılı başvuru ile gerekli izin alınmıştır. Elde edilen veriler betimleyici analizlerin yanı sıra, bağımsız örneklem t testi ile Anova testleri yardımıyla analiz edilmiştir. Araştırmanın sonuçlarına göre, hastane yöneticilerinin hemşirelerin örgütsel sessizlik nedenleri konusunda önemli rol oynadığı tespit edilmiştir.

Bu calisma, kuresel salgin surecinde bireylerin evde gecirdikleri sure zarfinda yasam tatmin duzeylerini tespit etmeyi amaclamaktadir. Arastirmanin evreni 18 yas uzeri, gonullu ve cevap verebilecek akli yetiye sahip kisilerden olusmaktadir. Arastirmanin orneklemini calismaya katilmayi kabul eden 1254 kisi olusturmaktadir. Arastirmanin verileri online formlar araciliǧiyla cesitli sosyal medya araclari (instagram, whatsapp, google formlar vb.) ile elde edilmistir. Elde edilen veriler betimleyici analizlerin yani sira, Mann Whitney U ve Kruskal Wallis testleri yardimiyla analiz edilmistir. Arastirmanin sonuclarina gore, belirtilen onlem unsurlarinin (maske, sosyal mesafe, hijyen vb.) hayata entegre (uyum) edilmesinin yasam tatmin duzeyi uzerinde onem arz ettiǧi tespit edilmistir. Ote yandan kisilerin yasam tatmin duzeyleri vasat ile yuksek duzey arasinda farklilik gostermektedir. Bu baǧlamda yasam tatmininde yuksek duzeyde yer alan unsurlarin maske, sosyal mesafe, hijyen vb. onlemler olduǧu belirlenirken, olcekte yer alan diǧer ifadelerin vasat duzeyde yer aldiǧi gozlemlenmektedir. Ayrica olcekte yer alan ifadeler icerisinde dusuk duzeyde yer alan tek ifadenin gunluk spor yapma olduǧu elde edilen diǧer sonuclar arasindadir.Alternate abstract:This study aimed to determine the life satisfaction levels of individuals during the time they spend at home during the global epidemic process. In the population of the research, every individual over the age of 18 who was voluntary and had the mental ability to respond was included. The data of the research were obtained by various social media tools (Instagram, WhatsApp, Google Forms, etc.) through online forms. In this context, the sample of the study consisted of 1,254 people. The data obtained were analyzed via Mann Whitney U and Kruskal Wallis tests as well as descriptive analysis. According to the results of the study, it was determined that the integration (adaptation) of the specified precautionary elements (mask, social distance, hygiene, etc.) to life was important in terms of the level of satisfaction with life. On the other hand, life satisfaction levels of people differed between average and high levels. In this context, it was observed that the factors that had a high-level part on life satisfaction were mask, social distance, hygiene, etc., while other expressions in the scale had a moderate level part. In addition, it is among the other results that the only expression that had a low-level part in the scale was daily exercise.

Bu çalışmada engelli bireylere yönelik algı düzeyini geçerli ile güvenilir şekilde ölçmek amacıyla bir “Engellilik Algısı Ölçeği” geliştirilmiştir. Geliştirilen bu ölçek kişilerin engelli bireylere yönelik algı düzeylerini incelemeyi ve çeşitli açılardan değerlendirmeyi amaçlamaktadır. Ölçek dört boyuttan oluşmaktan olup, likert tipidir. Ölçeğin ön uygulama formu Fırat Üniversitesi’nde öğrenim gören 385 öğrenciye uygulanmıştır. Ölçeğin yapı geçerliliğine yönelik yapılan faktör analizi sonucunda 8 maddenin yer aldığı birinci kısımda faktör yükü değerleri 0.75 ile 0.46 arasında olup, 6 maddenin yer aldığı ikinci kısımda bulunan maddelerin faktör yükü değerleri 0.64 ile 0.51 arasında değişmektedir. Üçüncü kısımda yer alan 4 maddenin faktör yükleri ise 0.67 ile 0.54 arasında olup, 2 maddenin yer aldığı dördüncü kısımda bulunan maddelerin faktör yükü değerleri 0.77 ile 0.68 arasında değişmektedir. Engellilik algısını ölçmeye yönelik faktörlerin toplam varyansın %50’sini açıkladığı belirlenmiştir. Ölçeğin güvenirlik katsayısı 0.86 bulunmuştur.

Bu çalışma, kültürel bağlamda hasta güveliği problemini incelemeyi amaçlamaktadır. Araştırma güvenlik ve hasta güvenliği kavramlarını konu edinmekle birlikte kültürel bağlamda hasta güvenliğine odaklanmaktadır. Sağlık çalışanlarının iş yapabilme biçimleri ve alışkanlıkları, çalışılan kurumda var olan örgütün iklimi ve kültürü, sağlık hizmeti alanların sağlık, hastalık ve hasta güvenliği konusundaki tutum, inanç, zihniyet ve sosyal ilişkilerin toplumun kültürel unsurlarıyla doğrudan ilişkili olduğunu söylemek mümkündür. Çalışmanın sonuçlarına göre, kültürel yapı sonucu oluşan örüntüleşmiş bazı davranış şekilleri, hastaların sağlığı ve güvenliği üzerinde bazen pozitif ve bazen de negatif etki oluşturabilmektedir. Söz konusu negatif etki ise, tedavinin gidişatında bir problem olarak ortaya çıkmaktadır.

Bu çalışma, insan hakları bağlamında hasta hakları ve sorumluluklarını konu edinmektedir. Araştırma, müracaatçıların, hasta hakları ve sorumlulukları hakkındaki bilgi düzeylerini belirlemeyi amaçlamaktadır. Bunun yanı sıra araştırma, hasta hakları ve sorumlulukları konusunda hastaların sahip olduğu bilgi düzeylerini ve tutumlarını da ortaya koymayı amaçlamaktadır. Çünkü hastaların sahip oldukları hakları bilmemeleri sağlık kuruluşlarında örselenme, ihmal ve istismar edilme; sorumluluklarını bilmemeleri ise sağlık kuruluşlarına sağlık çalışanlarına karşı şiddetin ortaya çıkmasına sebebiyet verdiğini söyleyebiliriz. Araştırmanın evrenini Tokat’ta bir devlet hastanesi oluşturmaktadır. Araştırmanın örneklemi ise ilgili hastaneden hizmet alan 247 hastadan ibarettir. Araştırmanın örnekleme yöntemi basit tesadüfi örnekleme yöntemidir. Her servisten eşit sayıda hasta sayısı amaçlanmış olup, çalışmaya katılmayı kabul eden hastalar ile uygulama gerçekleştirilmiştir. Araştırmanın elde edilen sonuçlarına göre, hastaların hakları ile sorumlulukları konusundaki bilgi düzeylerinin genel anlamda yüksek düzeyde olduğu tespit edilmiştir.

Bu çalışmada engelli bireylere yönelik algı düzeyini geçerli ile güvenilir şekilde ölçmek amacıyla bir “Engellilik Algısı Ölçeği” geliştirilmiştir. Geliştirilen bu ölçek kişilerin engelli bireylere yönelik algı düzeylerini incelemeyi ve çeşitli açılardan değerlendirmeyi amaçlamaktadır. Ölçek dört boyuttan oluşmaktan olup, likert tipidir. Ölçeğin ön uygulama formu Fırat Üniversitesi’nde öğrenim gören 385 öğrenciye uygulanmıştır. Ölçeğin yapı geçerliliğine yönelik yapılan faktör analizi sonucunda 8 maddenin yer aldığı birinci kısımda faktör yükü değerleri 0.75 ile 0.46 arasında olup, 6 maddenin yer aldığı ikinci kısımda bulunan maddelerin faktör yükü değerleri 0.64 ile 0.51 arasında değişmektedir. Üçüncü kısımda yer alan 4 maddenin faktör yükleri ise 0.67 ile 0.54 arasında olup, 2 maddenin yer aldığı dördüncü kısımda bulunan maddelerin faktör yükü değerleri 0.77 ile 0.68 arasında değişmektedir. Engellilik algısını ölçmeye yönelik faktörlerin toplam varyansın %50’sini açıkladığı belirlenmiştir. Ölçeğin güvenirlik katsayısı 0.86 bulunmuştur., In this study, it was aimed to develop a "Disability Perception Scale" that measures the perception level of persons with disabilities in a valid and reliable manner. This scale developed aims to examine the perception levels of people towards disabled individuals and evaluate them from various angles. The scale consists of four dimensions and is likert type. The pre-application form of the scale was applied to 385 students studying at Fırat University. As a result of the factor analysis conducted for the construct validity of the scale, the factor load values in the first part where there are 8 items are between 0.75 and 0.46, and the factor load values of the items in the second part where there are 6 items vary between 0.64 and 0.51. The factor loads of the 4 items in the third part are between 0.67 and 0.54, and the factor load values of the items in the fourth part, which includes 2 items, vary between 0.77 and 0.68. It has been determined that the factors for measuring the disability perception explain 50% of the total variance. The reliability coefficient of the scale was found to be 0.86.

Bu çalışma, engellilik algısını ölçmeyi ve mevcut olumsuz algıya ilişkin farkındalık yaratacak önerilerde bulunmayı amaçlamaktadır. Araştırma ağırlıklı olarak engelli bireylerin toplumsal yaşamda karşılaştıkları problemler ve sosyal dışlanmayı konu edinmekle birlikte üniversite öğrencilerinin engellilik algısı üzerinde odaklanmaktadır. Elde edilen sonuçlara göre, üniversite öğrencilerinin engellilik algısı genel anlamda vasat düzeydedir. Engelli bireylere yönelik uygulamaların genel anlamda engellilik algısını olumlu yönde farklılaştırdığı ve özellikle kamu spotlarının engellilik algısı üzerinde olumlu sonuçları olduğuna ilişkin bulgular saptanmıştır.

The CMS experiment at the LHC has measured the differential cross sections of Z bosons decaying to pairs of leptons, as functions of transverse momentum and rapidity, in lead-lead collisions at a nucleon-nucleon center-of-mass energy of 5.02 TeV . The measured Z boson elliptic azimuthal anisotropy coefficient is compatible with zero, showing that Z bosons do not experience significant final-state interactions in the medium produced in the collision. Yields of Z bosons are compared to Glauber model predictions and are found to deviate from these expectations in peripheral collisions, indicating the presence of initial collision geometry and centrality selection effects. The precision of the measurement allows, for the first time, for a data-driven determination of the nucleon-nucleon integrated luminosity as a function of lead-lead centrality, thereby eliminating the need for its estimation based on a Glauber model

A search for dark matter particles is performed using events with a Z boson candidate and large missing transverse momentum. The analysis is based on proton-proton collision data at a center-of-mass energy of 13 TeV, collected by the CMS experiment at the LHC in 2016-2018, corresponding to an integrated luminosity of 137 fb(-1). The search uses the decay channels Z -> ee and Z -> mu mu. No significant excess of events is observed over the background expected from the standard model. Limits are set on dark matter particle production in the context of simplified models with vector, axial-vector, scalar, and pseudoscalar mediators, as well as on a two-Higgs-doublet model with an additional pseudoscalar mediator. In addition, limits are provided for spin-dependent and spin-independent scattering cross sections and are compared to those from direct-detection experiments. The results are also interpreted in the context ofmodels of invisible Higgs boson decays, unparticles, and large extra dimensions.

The first measurement of the inclusive cross section for top quark pairs () produced in association with two additional charm jets is presented. The analysis uses the dileptonic final states of events produced in proton-proton collisions at a centre-of-mass energy of 13 TeV. The data correspond to an integrated luminosity of , recorded by the CMS experiment at the LHC. A new charm jet identification algorithm provides input to a neural network that is trained to distinguish among events with two additional charm (), bottom (), and light-flavour or gluon () jets. By means of a template fitting procedure, the inclusive , , and cross sections are simultaneously measured, together with their ratios to the inclusive + two jets cross section. This provides measurements of the and cross sections of and , respectively, in the full phase space. The results are compared and found to be consistent with predictions from two different matrix element generators with next-to-leading order accuracy in quantum chromodynamics, interfaced with a parton shower simulation.

A search is presented for supersymmetric partners of the top quark (top squarks) in final states with two oppositely charged leptons (electrons or muons), jets identified as originating from bquarks, and missing transverse momentum. The search uses data from proton-proton collisions at root s = 13 TeV collected with the CMS detector, corresponding to an integrated luminosity of 137 fb(-1). Hypothetical signal events are efficiently separated from the dominant top quark pair production background with requirements on the significance of the missing transverse momentum and on transverse mass variables. No significant deviation is observed from the expected background. Exclusion limits are set in the context of simplified supersymmetric models with pair-produced lightest top squarks. For top squarks decaying exclusively to a top quark and a lightest neutralino, lower limits are placed at 95% confidence level on the masses of the top squark and the neutralino up to 925 and 450 GeV, respectively. If the decay proceeds via an intermediate chargino, the corresponding lower limits on the mass of the lightest top squark are set up to 850 GeV for neutralino masses below 420 GeV. For top squarks undergoing a cascade decay through charginos and sleptons, the mass limits reach up to 1.4 TeV and 900 GeV respectively for the top squark and the lightest neutralino.

Results of the Model Unspecific Search in CMS (MUSiC), using proton-proton collision data recorded at the LHC at a centre-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 35.9 fb(-1), are presented. The MUSiC analysis searches for anomalies that could be signatures of physics beyond the standard model. The analysis is based on the comparison of observed data with the standard model prediction, as determined from simulation, in several hundred final states and multiple kinematic distributions. Events containing at least one electron or muon are classified based on their final state topology, and an automated search algorithm surveys the observed data for deviations from the prediction. The sensitivity of the search is validated using multiple methods. No significant deviations from the predictions have been observed. For a wide range of final state topologies, agreement is found between the data and the standard model simulation. This analysis complements dedicated search analyses by significantly expanding the range of final states covered using a model independent approach with the largest data set to date to probe phase space regions beyond the reach of previous general searches.

The strong Coulomb field created in ultrarelativistic heavy ion collisions is expected to produce a rapiditydependent difference (Av2) in the second Fourier coefficient of the azimuthal distribution (elliptic flow, v2) between D0 (uc) and D0 (uc) mesons. Motivated by the search for evidence of this field, the CMS detector at the LHC is used to perform the first measurement of Av2. The rapidity-averaged value is found to be (Av2) = 0.001 ? 0.001 (stat)? 0.003 (syst) in PbPb collisions at ?sNN = 5.02 TeV. In addition, the influence of the collision geometry is explored by measuring the D0 and D0mesons v2 and triangular flow coefficient (v3) as functions of rapidity, transverse momentum (pT), and event centrality (a measure of the overlap of the two Pb nuclei). A clear centrality dependence of prompt D0 meson v2 values is observed, while the v3 is largely independent of centrality. These trends are consistent with expectations of flow driven by the initial-state geometry. ? 2021 The Author. Published by Elsevier B.V. This is an open access article under the CC BY license

The production of Z boson pairs in proton–proton (pp) collisions, pp → (Z/γ ∗)(Z/γ ∗) → 22, where, = e or μ, is studied at a center-of-mass energy of 13 TeV with the CMS detector at the CERN LHC. The data sample corresponds to an integrated luminosity of 137 fb−1, collected during 2016–2018. The ZZ production cross section, σtot(pp → ZZ) = 17.4 ± 0.3 (stat) ± 0.5 (syst) ± 0.4 (theo)±0.3 (lumi) pb, measured for events with two pairs of opposite-sign, same-flavor leptons produced in the mass region 60 < m+− < 120 GeV is consistent with standard model predictions. Differential cross ections are also measured and agree with theoretical predictions. The invariant mass distribution of the our-lepton system is used to set limits on anomalous ZZZ and ZZγ couplings.

A search is performed for the rare decay W-+/--> pi(+/-)gamma in proton-proton collisions at root s = 13 TeV. Data corresponding to an integrated luminosity of 137 fb(-1) were collected during 2016 to 2018 with the CMS detector. This analysis exploits a novel search strategy based on W boson production in top quark pair events. An inclusive search for the W-+/--> pi(+/-)gamma decay is not optimal at the LHC because of the high trigger thresholds. Instead, a trigger selection is exploited in which the W boson originating from one of the top quarks is used to tag the event in a leptonic decay. The W boson emerging from the other top quark is used to search for the W-+/--> pi(+/-)gamma signature. Such decays are characterized by an isolated track pointing to a large energy deposit, and by an isolated photon of large transverse momentum. The presence of b quark jets reduces the background from the hadronization of light-flavor quarks and gluons. The W-+/- -> pi(+/-)gamma decay is not observed. An upper exclusion limit is set to this branching fraction, corresponding to 1.50 x 10(-5) at 95% confidence level, whereas the expected upper exclusion limit is 0.85(-0.29)(+0.52) x 10(-5). (C) 2021 The Author(s). Published by Elsevier B.V.

An inclusive search is presented for long-lived particles using displaced jets. The search uses a data sample collected with the CMS detector at the CERN LHC in 2017 and 2018, from proton-proton collisions at a center-of-mass energy of 13 TeV. The results of this search are combined with those of a previous search using a data sample collected with the CMS detector in 2016, yielding a total integrated luminosity of 132 fb − 1 . The analysis searches for the distinctive topology of displaced tracks and displaced vertices associated with a dijet system. For a simplified model, where pair-produced long-lived neutral particles decay into quark-antiquark pairs, pair production cross sections larger than 0.07 fb are excluded at 95% confidence level (C.L.) for long-lived particle masses larger than 500 GeV and mean proper decay lengths between 2 and 250 mm. For a model where the standard model-like Higgs boson decays to two long-lived scalar particles that each decays to a quark-antiquark pair, branching fractions larger than 1% are excluded at 95% C.L. for mean proper decay lengths between 1 mm and 340 mm. A group of supersymmetric models with pair-produced long-lived gluinos or top squarks decaying into various final-state topologies containing displaced jets is also tested. Gluino masses up to 2500 GeV and top squark masses up to 1600 GeV are excluded at 95% C.L. for mean proper decay lengths between 3 and 300 mm. The highest lower bounds on mass reach 2600 GeV for long-lived gluinos and 1800 GeV for long-lived top squarks. These are the most stringent limits to date on these models.

A search for leptoquarks produced singly and in pairs in proton-proton collisions is presented. We consider the leptoquark (LQ) to be a scalar particle of charge -1/3e coupling to a top quark plus a tau lepton (t tau) or a bottom quark plus a neutrino (b nu), or a vector particle of charge +2/3e, coupling to t nu or b tau. These choices are motivated by models that can explain a series of anomalies observed in the measurement of B meson decays. In this analysis the signatures t tau nu b and t tau nu are probed, using data recorded by the CMS experiment at the CERN LHC at root s = 13 TeV and that correspond to an integrated luminosity of 137 fb(-1). These signatures have not been previously explored in a dedicated search. The data are found to be in agreement with the standard model prediction. Lower limits at 95% confidence level are set on the LQ mass in the range 0.98-1.73 TeV, depending on the LQ spin and its coupling lambda to a lepton and a quark, and assuming equal couplings for the two LQ decay modes considered. These are the most stringent constraints to date on the existence of leptoquarks in this scenario. (C) 2021 The Author(s). Published by Elsevier B.V.

The physics motivation, detector design, triggers, calibration, alignment, simulation, and overall performance of the very forward CASTOR calorimeter of the CMS experiment are reviewed. The CASTOR Cherenkov sampling calorimeter is located very close to the LHC beam line, at a radial distance of about 1 cm from the beam pipe, and at 14.4 m from the CMS interaction point, covering the pseudorapidity range of −6.6 < �� < −5.2. It was designed to withstand high ambient radiation and strong magnetic fields. The performance of the detector in measurements of forward energy density, jets, and processes characterized by rapidity gaps, is reviewed using data collected in proton and nuclear collisions at the LHC.

Differential cross sections for the Drell-Yan process, including Z boson production, using the dimuon decay channel are measured in proton-lead (pPb) collisions at a nucleon-nucleon centre-of-mass energy of 8.16 TeV. A data sample recorded with the CMS detector at the LHC is used, corresponding to an integrated luminosity of 173 nb(-1). The differential cross section as a function of the dimuon mass is measured in the range 15-600 GeV, for the first time in proton-nucleus collisions. It is also reported as a function of dimuon rapidity over the mass ranges 15-60 GeV and 60-120 GeV, and ratios for the p-going over the Pb-going beam directions are built. In both mass ranges, the differential cross sections as functions of the dimuon transverse momentum p(T), and of a geometric variable phi* are measured, where phi* highly correlates with p(T), but is determined with higher precision. In the Z mass region, the rapidity dependence of the data indicate a modification of the distribution of partons within a lead nucleus as compared to the proton case. The data are more precise than predictions based upon current models of parton distributions.

A search is presented for a heavy vector resonance decaying into a Z boson and the standard model Higgs boson, where the Z boson is identified through its leptonic decays to electrons, muons, or neutrinos, and the Higgs boson is identified through its hadronic decays. The search is performed in a Lorentz-boosted regime and is based on data collected from 2016 to 2018 at the CERN LHC, corresponding to an integrated luminosity of 137fb−1. Upper limits are derived on the production of a narrow heavy resonance Z′, and a mass below 3.5 and 3.7TeV is excluded at 95% confidence level in models where the heavy vector boson couples predominantly to fermions and to bosons, respectively. These are the most stringent limits placed on the Heavy Vector Triplet Z′ model to date. If the heavy vector boson couples exclusively to standard model bosons, upper limits on the product of the cross section and branching fraction are set between 23 and 0.3fb for a Z′ mass between 0.8 and 4.6TeV, respectively. This is the first limit set on a heavy vector boson coupling exclusively to standard model bosons in its production and decay.

The second-order Fourier coefficients (v(2)) characterizing the azimuthal distributions of Y(1S) and Y(2S) mesons produced in PbPb collisions at root s(NN) = 5.02 TeV are studied. The Y mesons are reconstructed in their dimuon decay channel, as measured by the CMS detector. The collected data set corresponds to an integrated luminosity of 1.7 nb(-1). The scalar product method is used to extract the v2 coefficients of the azimuthal distributions. Results are reported for the rapidity range vertical bar y vertical bar < 2.4, in the transverse momentum interval 0 < pT < 50 GeV/c, and in three centrality ranges of 10-30%, 30-50% and 50-90%. In contrast to the J/psi mesons, the measured v(2) values for the Y mesons are found to be consistent with zero. (C) 2021 The Author(s). Published by Elsevier B.V.

The first measurements of production cross sections of polarized same-sign (WW +/-)-W-+/- boson pairs in proton-proton collisions are reported. The measurements are based on a data sample collected with the CMS detector at the LHC at a center-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 137 fb(-1). Events are selected by requiring exactly two same-sign leptons, electrons or muons, moderate missing transverse momentum, and two jets with a large rapidity separation and a large dijet mass to enhance the contribution of same-sign (WW +/-)-W-+/- scattering events. An observed (expected) 95% confidence level upper limit of 1.17 (0.88) fbis set on the production cross section for longitudinally polarized same-sign W-+/- W-+/- boson pairs. The electroweak production of same-sign W-+/- W-+/- boson pairs with at least one of the W bosons longitudinally polarized is measured with an observed (expected) significance of 2.3 (3.1) standard deviations. (C) 2020 The Author(s). Published by Elsevier B.V.

A measurement is reported of differential top quark pair (tt¯) production cross sections, where top quarks are produced at large transverse momenta. The data collected with the CMS detector at the LHC are from pp collisions at a center-of-mass energy of 13 TeV corresponding to an integrated luminosity of 35.9 fb-1. The measurement uses events where at least one top quark decays as t→Wb→qq¯′b and is reconstructed as a large-radius jet with transverse momentum in excess of 400 GeV. The second top quark is required to decay either in a similar way or leptonically, as inferred from a reconstructed electron or muon, a bottom quark jet, and missing transverse momentum due to the undetected neutrino. The cross section is extracted as a function of kinematic variables of individual top quarks or of the tt¯ system. The results are presented at the particle level, within a region of phase space close to that of the experimental acceptance, and at the parton level and are compared to various theoretical models. In both decay channels, the observed absolute cross sections are significantly lower than the predictions from theory, while the normalized differential measurements are well described

Dyslipidemia is the leading cause of cardiovascular mortality and morbidity. Reduction of lipids, particularly low-density lipoprotein cholesterol (LDL-C), with statins, significantly decreases the risk of cardiovascular events. Among different statins, pitavastatin, exhibits a peculiar pharmacokinetic and pharmacological profile. Indeed, differently from other statins, pitavastatin: a) is not metabolized by hepatic cytochrome CYP3A4 isoenzyme, therefore has a very low drug-drug interaction; b) has a similar or greater effect on LDL-C, c) is not associated with glucose metabolism impairment, and the risk of new onset diabetes is very low, d) increases high density lipoproteins (HDL) levels and, particularly, improves cholesterol efflux capacity of HDL, d) decreases cardiovascular outcome in primary and secondary prevention.

Event-by-event long-range correlations of azimuthal anisotropy Fourier coefficients (vn) in 8.16 TeV pPb data, collected by the CMS experiment at the CERN Large Hadron Collider, are extracted using a subevent four-particle cumulant technique applied to very low multiplicity events. Each combination of four charged particles is selected from either two, three, or four distinct subevent regions of a pseudorapidity range from −2.4 to 2.4 of the CMS tracker, and with transverse momentum between 0.3 and 3.0 GeV. Using the subevent cumulant technique, correlations between vn of different orders are measured as functions of particle ultiplicity and compared to the standard cumulant method without subevents over a wide event multiplicity range. At high multiplicities, the v2 and v3 coefficients exhibit an anticorrelation; this behavior is observed consistently using various methods. The v2 and v4 correlation strength is found to depend on the number of subevents used in the calculation. As the event multiplicity decreases, the results from different subevent methods diverge because of different contributions of noncollective or few-particle correlations. Correlations extracted with the four-subevent method exhibit a tendency to diminish monotonically toward the lowest multiplicity region (about 20 charged tracks) investigated. These findings extend previous studies to a significantly lower event multiplicity range and establish the evidence for the onset of long-range collective multiparticle correlations in small system collisions.

The Deep Underground Neutrino Experiment (DUNE), a 40-kton underground liquid argon time projection chamber experiment, will be sensitive to the electron-neutrino flavor component of the burst of neutrinos expected from the next Galactic core-collapse supernova. Such an observation will bring unique insight into the astrophysics of core collapse as well as into the properties of neutrinos. The general capabilities of DUNE for neutrino detection in the relevant few- to few-tens-of-MeV neutrino energy range will be described. As an example, DUNE's ability to constrain the nu(e) spectral parameters of the neutrino burst will be considered.

Evidence is presented for the electroweak (EW) production of two jets (jj) in association with two Z-bosons and constraints on anomalous quartic gauge couplings are set. The analysis is based on a data sample of proton-proton collisions at root s = 13 TeVcollected with the CMS detector in 2016-2018, and corresponding to an integrated luminosity of 137 fb(-1). The search is performed in the fully leptonic final state ZZ -> lll'l', where l, l' = e, mu. The EW production of two jets in association with two Zbosons is measured with an observed (expected) significance of 4.0 (3.5) standard deviations. The cross sections for the EW production are measured in three fiducial volumes and the result is sigma(EW)(pp -> ZZjj -> lll'l'jj) = 0.33(-0.10)(+0.11)(stat)(-0.03)(+0.04)(syst) fbin the most inclusive volume, in agreement with the standard model prediction of 0.275 +/- 0.021fb. Measurements of total cross sections for jj production in association with two Zbosons are also reported. Limits on anomalous quartic gauge couplings are derived in terms of the effective field theory operators T0, T1, T2, T8, and T9. (C) 2020 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY license.

Angular distributions of the decay B+-> K*(892)(+)mu(+)mu(-) are studied using events collected with the CMS detector in root s = 8 TeV proton-proton collisions at the LHC, corresponding to an integrated luminosity of 20.0 fb(-1). The forward-backward asymmetry of the muons and the longitudinal polarization of the K*(892)(+) meson are determined as a function of the square of the dimuon invariant mass. These are the first results from this exclusive decay mode and are in agreement with a standard model prediction.

Collinear (small-angle) and large-angle, as well as soft and hard radiations are investigated in three-jet and Z + two-jet events collected in proton-proton collisions at the LHC. The normalized production cross sections are measured as a function of the ratio of transverse momenta of two jets and their angular separation. The measurements in the three-jet and Z + two-jet events are based on data collected at a center-of-mass energy of 8 TeV, corresponding to an integrated luminosity of 19.8 fb(-1). The Z + two-jet events are reconstructed in the dimuon decay channel of the Z boson. The three-jet measurement is extended to include root s = 13 TeV data corresponding to an integrated luminosity of 2.3 fb(-1). The results are compared to predictions from event generators that include parton showers, multiple parton interactions, and hadronization. The collinear and soft regions are in general well described by parton showers, whereas the regions of large angular separation are often best described by calculations using higher-order matrix elements.

A search is presented for a heavy vector resonance decaying into a Z boson and the standard model Higgs boson, where the Z boson is identified through its leptonic decays to electrons, muons, or neutrinos, and the Higgs boson is identified through its hadronic decays. The search is performed in a Lorentz-boosted regime and is based on data collected from 2016 to 2018 at the CERN LHC, corresponding to an integrated luminosity of 137 fb-1. Upper limits are derived on the production of a narrow heavy resonance Z ', and a mass below 3.5 and 3.7 Te is excluded at 95% confidence level in models where the heavy vector boson couples predominantly to fermions and to bosons, respectively. These are the most stringent limits placed on the Heavy Vector Triplet Z ' model to date. If the heavy vector boson couples exclusively to standard model bosons, upper limits on the product of the cross section and branching fraction are set between 23 and 0.3 fb for a Z ' mass between 0.8 and 4.6 Te, respectively. This is the first limit set on a heavy vector boson coupling exclusively to standard model bosons in its production and decay.

Results are reported from a search for the lepton flavor violating decay τ → 3µ in proton-proton collisions at √ s = 13 TeV. The data sample corresponds to an integrated luminosity of 33.2 fb−1 recorded by the CMS experiment at the LHC in 2016. The search exploits τ leptons produced in both W boson and heavy-flavor hadron decays. No significant excess above the expected background is observed. An upper limit on the branching fraction B(τ → 3µ) of 8.0 × 10−8 at 90% confidence level is obtained, with an expected upper limit of 6.9 × 10−8.

The CP-violating weak phase ?s and the decay width difference ??s between the light and heavy B0s mass eigenstates are measured with the CMS detector at the LHC in a sample of 48 500 reconstructed B0s? J/I) d (1020) ?11+11? K+K? events. The measurement is based on a data sample corresponding to an integrated luminosity of 96.4 fb?1, collected in proton-proton collisions at ?s = 13 TeV in 2017?2018. To extract the values of ?s and ??s, a time-dependent and flavor-tagged angular analysis of the 11+11?K+K? final state is performed. The analysis employs a dedicated tagging trigger and a novel opposite-side muon flavor tagger based on machine learning techniques. The measurement yields ?s = ?11 ?50 (stat) ? 10 (syst) mrad and ??s = 0.114 ? 0.014 (stat)? 0.007 (syst) ps?1, in agreement with the standard model predictions. When combined with the previous CMS measurement at ?s = 8 TeV, the following values are obtained: ?s = ?21 ? 44 (stat) ? 10 (syst) mrad, ??s = 0.1032 ? 0.0095 (stat) ? 0.0048 (syst) ps?1, a significant improvement over the 8 TeV result. ? 2021 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY license

Objective: Activated macrophages (M1-type macrophages) in adipose tissue secrete many proinflammatory cytokines that induce insulin resistance (IR). Oncostatin M (OSM), a member of the interleukin-6 (IL-6) family of Gp130 cytokines, plays an important role in a variety of biological functions, including the regulation of inflammatory responses. Proinflammatory cytokines released in patients with IR trigger a chronic, low-grade inflammatory reaction in blood vessel walls. This inflammator response leads to endothelial damage, which is the main mechanism for atherosclerosis and many cardiovascular diseases. Animal studies have reported a relationship between OSM and IR. To the best of our knowledge, however, few clinical studies have examined this topic. Therefore, we studied the relationship between serum levels of OSM and IR. Subjects and methods: This prospective cross-sectional case-control study enrolled 50 people with IR (according to the HOMA-IR and QUICKI indices) and 34 healthy controls. The fasting blood concentrations of insulin, glucose, blood urea nitrogen (BUN), creatinine, aspartate aminotransferase (AST), alanine aminotransferase (ALT), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), triglyceride, total cholesterol, C-reactive protein (CRP), and OSM were determined. Results: There were no significant differences between the two groups in age, sex, and HbA1c levels. Univariate analyses showed that waist circumference (WC) and levels of fasting glucose, insulin, CRP, HDL-C, OSM, HOMA-IR, and QUICKI differed between the two study groups. In multivariate analyses, both IR indices (QUICKI and HOMA) and OSM differed between the two groups. Conclusion: OSM was correlated with the IR indices (QUICKI and HOMA). For simplicity, it might replace the other IR indices in the future. Further detailed studies are needed to confirm this.

The second-order Fourier coefficients (v(2)) characterizing the azimuthal distributions of Y(1S) and Y(2S) mesons produced in PbPb collisions at root s(NN) = 5.02 TeV are studied. The Y mesons are reconstructed in their dimuon decay channel, as measured by the CMS detector. The collected data set corresponds to an integrated luminosity of 1.7 nb(-1). The scalar product method is used to extract the v2 coefficients of the azimuthal distributions. Results are reported for the rapidity range vertical bar y vertical bar < 2.4, in the transverse momentum interval 0 < pT < 50 GeV/c, and in three centrality ranges of 10-30%, 30-50% and 50-90%. In contrast to the J/psi mesons, the measured v(2) values for the Y mesons are found to be consistent with zero. (C) 2021 The Author(s). Published by Elsevier B.V.

Modifications to the distribution of charged particles with respect to high transverse momentum (p(T)) jets passing through a quark-gluon plasma are explored using the CMS detector. Back-to-back dijets are analyzed in lead-lead and proton-proton collisions at root s(NN) = 5.02 TeV via correlations of charged particles in bins of relative pseudorapidity and angular distance from the leading and subleading jet axes. In comparing the lead-lead and proton-proton collision results, modifications to the charged-particle relative distance distribution and to the momentum distributions around the jet axis are found to depend on the dijet momentum balance x(j) , which is the ratio between the subleading and leading jet p(T). For events with x(j) approximate to 1, these modifications are observed for both the leading and subleading jets. However, while subleading jets show significant modifications for events with a larger dijet momentum imbalance, much smaller modifications are found for the leading jets in these events.