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1. Electronic malignant bowel obstruction symptom monitoring smartphone application for patients with gynecologic cancers

Author

Madariaga, Ainhoa, Jivraj, Nazlin, Soberanis Pina, Pamela, Somji, Faiza, Truong, Tran, Melwani, Sheena, Lovas, Mike, Gogos, Terri-Ann, Sajewycz, Katrina, Bhat, Gita, Alqaisi, Husam, Gonzalez-Ochoa, Eduardo, Veneziani, Ana, Garg, Vikas, Dhani, Neesha C, Grant, Robert, Bowering, Valerie, Oza, Amit M, Wang, Lisa, Berlin, Alejandro, Lheureux, Stephanie, and Foote, Janie

Published
2024
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3. Simulated dose painting of hypoxic sub-volumes in pancreatic cancer stereotactic body radiotherapy

Author

Elamir, Ahmed M., Stanescu, Teodor, Shessel, Andrea, Tadic, Tony, Yeung, Ivan, Letourneau, Daniel, Kim, John, Lukovic, Jelena, Dawson, Laura A., Wong, Rebecca, Barry, Aisling, Brierley, James, Gallinger, Steven, Knox, Jennifer, O'Kane, Grainne, Dhani, Neesha, Hosni, Ali, and Taylor, Edward

Subjects
Physics - Medical Physics
Abstract

Dose painting of hypoxic tumour sub-volumes using positron-emission tomography (PET) has been shown to improve tumour control in silico in several sites. Pancreatic cancer presents a more stringent challenge, given its proximity to critical organs-at-risk (OARs) and anatomic motion. A radiobiological model was developed to estimate clonogen survival fraction (SF), using 18F-fluoroazomycin arabinoside PET (FAZA PET) images from ten patients with pancreatic cancer to quantify oxygen enhancement effects. For each patient, four simulated five-fraction stereotactic body radiotherapy (SBRT) plans were generated: 1) a standard SBRT plan aiming to cover the planning target volume with 40 Gy, 2) dose painting plans delivering escalated doses to FAZA-avid hypoxic sub-volumes, 3) dose painting plans with simulated spacer separating the duodenum and pancreatic head, and 4), plans with integrated boosts to geometric contractions of the tumour (GTV). All plans saturated at least one OAR dose limit. SF was calculated for each plan and sensitivity of SF to simulated hypoxia quantification errors was evaluated. Dose painting resulted in a 55% reduction in SF as compared to standard SBRT; 78% with spacer. Integrated boosts to hypoxia-blind geometric contractions resulted in a 41% reduction in SF. The reduction in SF for dose-painting plans persisted for all hypoxia quantification parameters studied, including registration and rigid motion errors that resulted in shifts and rotations of the GTV and hypoxic sub-volumes by as much as 1 cm and 10 degrees. Although proximity to OARs ultimately limited dose escalation, with estimated SFs (~10^-5) well above levels required to completely ablate a ~10 cm^3 tumour, dose painting robustly reduced clonogen survival when accounting for expected treatment and imaging uncertainties and thus, may improve local response and associated morbidity.

Published
2021
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4. Clinical outcome and biomarker assessments of a multi-centre phase II trial assessing niraparib with or without dostarlimab in recurrent endometrial carcinoma

Author

Madariaga, Ainhoa, Garg, Swati, Tchrakian, Nairi, Dhani, Neesha C., Jimenez, Waldo, Welch, Stephen, MacKay, Helen, Ethier, Josee-Lyne, Gilbert, Lucy, Li, Xuan, Rodriguez, Angela, Chan, Lucy, Bowering, Valerie, Clarke, Blaise, Zhang, Tong, King, Ian, Downs, Gregory, Stockley, Tracy, Wang, Lisa, Udagani, Smitha, Oza, Amit M., and Lheureux, Stephanie

Published
2023
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5. Myasthenia Gravis in Patients Treated With Immune Checkpoint Inhibitors

Author

Alghabban, Abdulrahman, Corke, Lucy, Katzberg, Hans, Bril, Vera, Barnett-Tapia, Carolina, Mason, Warren, Alothman, Raed, Albiruni Ryan, Abdul Razak, Hogg, David, Sridhar, Srikala, Dhani, Neesha, Spreafico, Anna, Eng, Lawson, Sacher, Adrian, Bradbury, Penelope, Liu, Geoffrey, Leighl, Natasha, and Shepherd, Frances A.

Published
2024
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6. Phase 1 study to determine the safety and dosing of autologous PBMCs modified to present HPV16 antigens (SQZ-PBMC-HPV) in HLA-A*02+ patients with HPV16+ solid tumors

Author

Jimeno, Antonio, Baranda, Joaquina, Iams, Wade T., Park, Jong Chul, Mita, Monica, Gordon, Michael S., Taylor, Matthew, Dhani, Neesha, Leal, Alexis D., Neupane, Prakash, Eng, Cathy, Yeku, Oladapo, Mita, Alain, Moser, Justin C., Butler, Marcus, Loughhead, Scott M., Jennings, Julia, Miselis, Nathan R., Ji, Rui-Ru, Nair, Nitya, Kornacker, Martin, Zwirtes, Ricardo F., Bernstein, Howard, and Sharei, Armon

Published
2023
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7. Symptom screening with Targeted Early Palliative care (STEP) versus usual care for patients with advanced cancer: a mixed methods study

Author

Zimmermann, Camilla, Pope, Ashley, Hannon, Breffni, Bedard, Philippe L., Rodin, Gary, Dhani, Neesha, Li, Madeline, Herx, Leonie, Krzyzanowska, Monika K., Howell, Doris, Knox, Jennifer J., Leighl, Natasha B., Sridhar, Srikala, Oza, Amit M., Lheureux, Stephanie, Booth, Christopher M., Liu, Geoffrey, Castro, Jacqueline Alcalde, Swami, Nadia, Sue-A-Quan, Rachel, Rydall, Anne, and Le, Lisa W.

Published
2023
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9. Patient self-reporting of tolerability using PRO-CTCAE in a randomized double-blind, placebo-controlled phase II trial comparing gemcitabine in combination with adavosertib or placebo in patients with platinum resistant or refractory epithelial ovarian carcinoma

Author

Madariaga, Ainhoa, Mitchell, Sandra A., Pittman, Tyler, Wang, Lisa, Bowering, Valerie, Kavak, Nisan, Quintos, Judy, Chang, Karen, Ramsahai, Janelle, Karakasis, Katherine, Welch, Stephen A., Dhani, Neesha C., Lheureux, Stephanie, and Oza, Amit M.

Published
2022
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10. Precision oncology for rare gynecologic malignancies: Integrating molecular tumor boards and real-time treatment matching.

Author

Grant, Brooke, primary, Pannu, Anmol Kaur, additional, Bowering, Valerie, additional, Veneziani, Ana, additional, Soberanis Pina, Pamela, additional, Gonzalez-Ochoa, Eduardo, additional, Alqaisi, Husam, additional, Garg, Vikas, additional, Braik, Dina, additional, Hodgson, Anjelica, additional, Rouzbahman, Marjan, additional, Chawla, Tanya, additional, Msan, Anthony, additional, Siman, Steven, additional, King, Ian, additional, Stockley, Tracy, additional, Grant, Robert C, additional, Dhani, Neesha C., additional, Lheureux, Stephanie, additional, and Oza, Amit M., additional

Published
2024
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11. Molecular characterization of cervical cancer histological subtypes: The VENUS study.

Author

Braik, Dina, primary, Alqaisi, Husam, additional, Garg, Vikas, additional, Soberanis Pina, Pamela, additional, Valente Lage, Liana, additional, Veneziani, Ana, additional, Grant, Brooke, additional, Pannu, Anmol Kaur, additional, Lajkosz, Katherine, additional, Msan, Anthony, additional, Hodgson, Anjelica, additional, Rouzbahman, Marjan, additional, Stockley, Tracy, additional, Bowering, Valerie, additional, Grant, Robert C, additional, Dhani, Neesha C., additional, Lheureux, Stephanie, additional, and Oza, Amit M., additional

Published
2024
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12. Phase II randomized multi-centre study of neoadjuvant olaparib in patients with platinum sensitive relapsed high grade serous ovarian cancer: The NEO trial.

Author

Lheureux, Stephanie, primary, May, Taymaa, additional, Wilson, Michelle K., additional, Provencher, Diane M., additional, Lau, Susie, additional, Ghatage, Prafull, additional, Weberpals, Johanne I, additional, Banerjee, Susana N., additional, McNeish, Iain A., additional, Dhani, Neesha C., additional, Ferguson, Sarah, additional, Bouchard-Fortier, Genevieve, additional, Pugh, Trevor John, additional, Ye, Xiang Y, additional, Garisto, Sarah, additional, Quintos, Judy, additional, Ramsahai, Janelle, additional, Wong, Horace, additional, Bowering, Valerie, additional, and Oza, Amit M., additional

Published
2024
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13. Adavosertib plus gemcitabine for platinum-resistant or platinum-refractory recurrent ovarian cancer: a double-blind, randomised, placebo-controlled, phase 2 trial

Author

Lheureux, Stephanie, Cristea, Mihaela C, Bruce, Jeffrey P, Garg, Swati, Cabanero, Michael, Mantia-Smaldone, Gina, Olawaiye, Alexander B, Ellard, Susan L, Weberpals, Johanne I, Wahner Hendrickson, Andrea E, Fleming, Gini F, Welch, Stephen, Dhani, Neesha C, Stockley, Tracy, Rath, Prisni, Karakasis, Katherine, Jones, Gemma N, Jenkins, Suzanne, Rodriguez-Canales, Jaime, Tracy, Michael, Tan, Qian, Bowering, Valerie, Udagani, Smitha, Wang, Lisa, Kunos, Charles A, Chen, Eric, Pugh, Trevor J, and Oza, Amit M

Published
2021
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14. Don't drop the baton: A multidisciplinary and interprofessional approach to improving transfer of accountability and information transfer (TOAI).

Author

Ali, Anum, Glinsky, Victoria, Macedo, Alyssa, Weatherby, Hilary, Bagnarol, Rebecca, Mak, Ernie, Acharya, Ishan, Hirsch, Ian, Sanz Garcia, Enrique, Costa, Ana Luisa, Grande, Claudia, Dawes, Pearlina, Hahn, Ezra, Leung, Eugene, Thyagu, Santhosh, Gupta, Vikas, Viswabandya, Auro, Julius, Anet, Krzyzanowska, Monika K., and Dhani, Neesha C.

Published
2024
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16. Corrigendum to Research biopsies in patients with gynecologic cancers: patient-reported outcomes, perceptions, and preferences

Author

Madariaga, Ainhoa, primary, Bhat, Gita, additional, Wilson, Michelle K., additional, Li, Xuan, additional, Cyriac, Sunu, additional, Bowering, Valerie, additional, Hunt, Wendy, additional, Gutierrez, David, additional, Bonilla, Luisa, additional, Kasherman, Lawrence, additional, McMullen, Michelle, additional, Wang, Lisa, additional, Ghai, Sangeet, additional, Dhani, Neesha C., additional, Oza, Amit M., additional, and Lheureux, Stephanie, additional

Published
2024
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18. Abstract A074: Maveropepimut-S, a DPX-based immune-educating therapy, combined with Pembrolizumab and Cyclophosphamide in recurrent ovarian cancer, results from the Phase 1/2 PESCO Trial

Author

Veneziani, Ana C., primary, Alqaisi, Husam, additional, Millar, Douglas G, additional, Colombo, Ilaria, additional, Gonzalez-Ochoa, Eduardo, additional, Atale, Swati, additional, Msan, Anthony, additional, Quintos, Judy, additional, Ramsahai, Janelle, additional, Garg, Vikas, additional, Soberanis, Pamela, additional, Dhani, Neesha C, additional, Grant, Robert C, additional, Wang, Lisa, additional, Bowering, Valerie, additional, Lheureux, Stephanie, additional, Ohashi, Pamela S, additional, and Oza, Amit M, additional

Published
2024
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19. Neoadjuvant therapy and major arterial resection for potentially reconstructable arterial involvement by stage 3 adenocarcinoma of the pancreas

Author

Loveday, Benjamin P.T., Zilbert, Nathan, Serrano, Pablo E., Tomiyama, Koji, Tremblay, Amélie, Fox, Adrian M., Segedi, Maja, O'Malley, Martin, Borgida, Ayelet, Bianco, Teresa, Creighton, Sean, Dodd, Anna, Fraser, Adriana, Moore, Malcolm, Kim, John, Cleary, Sean, Moulton, Carol-anne, Greig, Paul, Wei, Alice C., Gallinger, Steven, Dhani, Neesha, and McGilvray, Ian D.

Published
2019
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20. Final outcomes analysis of the cell product SQZ‐PBMC‐HPV Phase 1 trial in incurable HPV16+ solid tumors shows improved overall survival in patients with increased CD8+ T cell tumor infiltration.

Author

Weaver, Alice N., Iams, Wade T., Park, Jong Chul, Mita, Monica, Holtick, Udo, Gordon, Michael S., Rodabaugh, Kerry J., Dhani, Neesha, Neupane, Prakash, Taylor, Matthew, Amanda Duvall, E., Jennings, Julia, Miselis, Nathan R., Loughhead, Scott, Warren, Marshelle S., Bernstein, Howard, Klussmann, Jens P., Baranda, Joaquina, and Jimeno, Antonio

Published
2024
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32. Molecular Profiling of Patients With Advanced Colorectal Cancer: Princess Margaret Cancer Centre Experience

Author

Chiu, Joanne W., Krzyzanowska, Monika K., Serra, Stefano, Knox, Jennifer J., Dhani, Neesha C., Mackay, Helen, Hedley, David, Moore, Malcolm, Liu, Geoffrey, Burkes, Ronald L., Brezden-Masley, Christine, Roehrl, Michael H., Craddock, Kenneth J., Tsao, Ming-Sound, Zhang, Tong, Yu, Celeste, Kamel-Reid, Suzanne, Siu, Lillian L., Bedard, Philippe L., and Chen, Eric X.

Published
2018
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33. 594 SQZ-PBMC-HPV-101: Increased overall survival in a subset of patients with recurrent, locally advanced, or metastatic HPV16+tumors treated with cell-based vaccine, SQZ-PBMC-HPV

Author

Jimeno, Antonio, primary, Iams, Wade T, additional, Park, Jong Chul, additional, MitaSc, Monica, additional, Holtick, Udo, additional, Gordon, Michael S, additional, Rodabaugh, Kerry J, additional, Dhani, Neesha, additional, Taylor, Matthew H, additional, Amanda Duvall, E, additional, Jennings, Julia, additional, Miselis, Nathan, additional, Loughhead, Scott, additional, Warren, Marshelle S, additional, Bernstein, Howard, additional, and Baranda, Joaquina, additional

Published
2023
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34. Supplementary Table S4 from Identifying Mechanisms of Resistance by Circulating Tumor DNA in EVOLVE, a Phase II Trial of Cediranib Plus Olaparib for Ovarian Cancer at Time of PARP Inhibitor Progression

Author

Lheureux, Stephanie, primary, Prokopec, Stephenie D., primary, Oldfield, Leslie E., primary, Gonzalez-Ochoa, Eduardo, primary, Bruce, Jeffrey P., primary, Wong, Derek, primary, Danesh, Arnavaz, primary, Torti, Dax, primary, Torchia, Jonathan, primary, Fortuna, Alexander, primary, Singh, Sharanjit, primary, Irving, Matthew, primary, Marsh, Kayla, primary, Lam, Bernard, primary, Speers, Vanessa, primary, Yosifova, Aleksandra, primary, Oaknin, Ana, primary, Madariaga, Ainhoa, primary, Dhani, Neesha C., primary, Bowering, Valerie, primary, Oza, Amit M., primary, and Pugh, Trevor J., primary

Published
2023
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35. Supplementary Figure S4 from Identifying Mechanisms of Resistance by Circulating Tumor DNA in EVOLVE, a Phase II Trial of Cediranib Plus Olaparib for Ovarian Cancer at Time of PARP Inhibitor Progression

Author

Lheureux, Stephanie, primary, Prokopec, Stephenie D., primary, Oldfield, Leslie E., primary, Gonzalez-Ochoa, Eduardo, primary, Bruce, Jeffrey P., primary, Wong, Derek, primary, Danesh, Arnavaz, primary, Torti, Dax, primary, Torchia, Jonathan, primary, Fortuna, Alexander, primary, Singh, Sharanjit, primary, Irving, Matthew, primary, Marsh, Kayla, primary, Lam, Bernard, primary, Speers, Vanessa, primary, Yosifova, Aleksandra, primary, Oaknin, Ana, primary, Madariaga, Ainhoa, primary, Dhani, Neesha C., primary, Bowering, Valerie, primary, Oza, Amit M., primary, and Pugh, Trevor J., primary

Published
2023
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36. Data from Identifying Mechanisms of Resistance by Circulating Tumor DNA in EVOLVE, a Phase II Trial of Cediranib Plus Olaparib for Ovarian Cancer at Time of PARP Inhibitor Progression

Author

Lheureux, Stephanie, primary, Prokopec, Stephenie D., primary, Oldfield, Leslie E., primary, Gonzalez-Ochoa, Eduardo, primary, Bruce, Jeffrey P., primary, Wong, Derek, primary, Danesh, Arnavaz, primary, Torti, Dax, primary, Torchia, Jonathan, primary, Fortuna, Alexander, primary, Singh, Sharanjit, primary, Irving, Matthew, primary, Marsh, Kayla, primary, Lam, Bernard, primary, Speers, Vanessa, primary, Yosifova, Aleksandra, primary, Oaknin, Ana, primary, Madariaga, Ainhoa, primary, Dhani, Neesha C., primary, Bowering, Valerie, primary, Oza, Amit M., primary, and Pugh, Trevor J., primary

Published
2023
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38. Impact of an Inter-Professional Clinic on Pancreatic Cancer Outcomes: A Retrospective Cohort Study.

Author

Moffat, Gordon Taylor, Coyne, Zachary, Albaba, Hamzeh, Aung, Kyaw Lwin, Dodd, Anna, Espin-Garcia, Osvaldo, Moura, Shari, Gallinger, Steven, Kim, John, Fraser, Adriana, Hutchinson, Shawn, Moulton, Carol-Anne, Wei, Alice, McGilvray, Ian, Dhani, Neesha, Jang, Raymond, Elimova, Elena, Moore, Malcolm, Prince, Rebecca, and Knox, Jennifer

Subjects
PANCREATIC cancer, ALLIED health personnel, CANCER prognosis, MEDICAL personnel, COHORT analysis
Abstract

Background: Pancreatic ductal adenocarcinoma (PDAC) presents significant challenges in diagnosis, staging, and appropriate treatment. Furthermore, patients with PDAC often experience complex symptomatology and psychosocial implications that require multi-disciplinary and inter-professional supportive care management from health professionals. Despite these hurdles, the implementation of inter-professional clinic approaches showed promise in enhancing clinical outcomes. To assess the effectiveness of such an approach, we examined the impact of the Wallace McCain Centre for Pancreatic Cancer (WMCPC), an inter-professional clinic for patients with PDAC at the Princess Margaret Cancer Centre (PM). Methods: This retrospective cohort study included all patients diagnosed with PDAC who were seen at the PM before (July 2012–June 2014) and after (July 2014–June 2016) the establishment of the WMCPC. Standard therapies such as surgery, chemotherapy, and radiation therapy remained consistent across both time periods. The cohorts were compared in terms of survival rates, disease stage, referral patterns, time to treatment, symptoms, and the proportion of patients assessed and supported by nursing and allied health professionals. Results: A total of 993 patients were included in the review, comprising 482 patients pre-WMCPC and 511 patients post-WMCPC. In the multivariate analysis, adjusting for ECOG (Eastern Cooperative Oncology Group) and stage, it was found that post-WMCPC patients experienced longer median overall survival (mOS, HR 0.84, 95% CI 0.72–0.98, p = 0.023). Furthermore, the time from referral to initial consultation date decreased significantly from 13.4 to 8.8 days in the post-WMCPC cohort (p < 0.001), along with a reduction in the time from the first clinic appointment to biopsy (14 vs. 8 days, p = 0.022). Additionally, patient-reported well-being scores showed improvement in the post-WMCPC cohort (p = 0.02), and these patients were more frequently attended to by nursing and allied health professionals (p < 0.001). Conclusions: The implementation of an inter-professional clinic for patients diagnosed with PDAC led to improvements in overall survival, patient-reported well-being, time to initial assessment visit and pathological diagnosis, and symptom management. These findings advocate for the adoption of an inter-professional clinic model in the treatment of patients with PDAC. [ABSTRACT FROM AUTHOR]

Published
2024
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41. Identifying Mechanisms of Resistance by Circulating Tumor DNA in EVOLVE, a Phase II Trial of Cediranib Plus Olaparib for Ovarian Cancer at Time of PARP Inhibitor Progression

Author

Lheureux, Stephanie, primary, Prokopec, Stephenie D., additional, Oldfield, Leslie E., additional, Gonzalez-Ochoa, Eduardo, additional, Bruce, Jeffrey P., additional, Wong, Derek, additional, Danesh, Arnavaz, additional, Torti, Dax, additional, Torchia, Jonathan, additional, Fortuna, Alexander, additional, Singh, Sharanjit, additional, Irving, Matthew, additional, Marsh, Kayla, additional, Lam, Bernard, additional, Speers, Vanessa, additional, Yosifova, Aleksandra, additional, Oaknin, Ana, additional, Madariaga, Ainhoa, additional, Dhani, Neesha C., additional, Bowering, Valerie, additional, Oza, Amit M., additional, and Pugh, Trevor J., additional

Published
2023
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43. Adjuvant nab-Paclitaxel + Gemcitabine in Resected Pancreatic Ductal Adenocarcinoma: Results From a Randomized, Open-Label, Phase III Trial

Author

Tempero, Margaret A., primary, Pelzer, Uwe, additional, O'Reilly, Eileen M., additional, Winter, Jordan, additional, Oh, Do-Youn, additional, Li, Chung-Pin, additional, Tortora, Giampaolo, additional, Chang, Heung-Moon, additional, Lopez, Charles D., additional, Bekaii-Saab, Tanios, additional, Ko, Andrew H., additional, Santoro, Armando, additional, Park, Joon Oh, additional, Noel, Marcus S., additional, Frassineti, Giovanni Luca, additional, Shan, Yan-Shen, additional, Dean, Andrew, additional, Riess, Hanno, additional, Van Cutsem, Eric, additional, Berlin, Jordan, additional, Philip, Philip, additional, Moore, Malcolm, additional, Goldstein, David, additional, Tabernero, Josep, additional, Li, Mingyu, additional, Ferrara, Stefano, additional, Le Bruchec, Yvan, additional, Zhang, George, additional, Lu, Brian, additional, Biankin, Andrew V., additional, Reni, Michele, additional, Epstein, Richard, additional, Vasey, Paul, additional, Shapiro, Jeremy, additional, Burge, Matthew, additional, Chua, Yu Jo, additional, Harris, Marion, additional, Pavlakis, Nick, additional, Tebbutt, Niall, additional, Prager, Gerald, additional, Dittrich, Christian, additional, Längle, Friedrich, additional, Philipp-Abbrederis, Kathrin, additional, Greil, Richard, additional, Stöger, Herbert, additional, Girschikofsky, Michael, additional, Kuehr, Thomas, additional, Van Laethem, Jean-Luc, additional, Laurent, Stéphanie, additional, Dhani, Neesha, additional, Ko, Yoo Joung, additional, Dowden, Scot, additional, Kavan, Petr, additional, Tehfe, Mustapha Édouard, additional, Kubala, Eugen, additional, Kohoutek, Milan, additional, Pfeiffer, Per, additional, Yilmaz, Mette, additional, Parner, Vibeke, additional, Salminen, Tapio, additional, Soveri, Leena-Maija, additional, Korkeila, Eija, additional, Osterlund, Pia, additional, Taieb, Julien, additional, Tougeron, David, additional, Artru, Pascal, additional, Caroli-Bosc, François Xavier, additional, Guimbaud, Rosine, additional, Turpin, Antony, additional, Walter, Thomas, additional, Bachet, Jean Baptiste, additional, Kunzmann, Volker, additional, Kreth, Florian, additional, Block, Andreas, additional, Venerito, Marino, additional, Oettle, Helmut, additional, Karthaus, Meinolf, additional, Trojan, Jörg, additional, Folprecht, Gunnar, additional, Lerch, Markus, additional, Kullmann, Frank, additional, Reiser, Marcel, additional, Heinemann, Volker, additional, Wörns, Marcus-Alexander, additional, Schulz, Holger, additional, Garlipp, Benjamin, additional, Yau, Thomas, additional, Chan, Lam Stephen, additional, Juhasz, Balazs, additional, Landherr, László, additional, Pinter, Tamas, additional, Bodoky, György, additional, Kahán, Zsuzsanna, additional, McDermott, Raymond, additional, Power, Derek, additional, Gianni, Luca, additional, Siena, Salvatore, additional, Milella, Michele, additional, Falcone, Alfredo, additional, Berardi, Rossana, additional, Bagalà, Cinzia, additional, Di Costanzo, Francesco, additional, Roila, Fausto, additional, Ardizzoni, Andrea, additional, Maiello, Evaristo, additional, Fanello, Silvia, additional, Wilmink, Johanna, additional, Willem de Groot, Jan, additional, Creemers, Geert, additional, Barroso, Eduardo, additional, Rodrigues, Tânia, additional, Sarmento, Cristina, additional, Chee, Cheng Ean, additional, Tai, David, additional, Mercade, Teresa Macarulla, additional, Medina, Manuel Hidalgo, additional, Mena, Alfredo Carrato, additional, Santasusana, Joan Maurel, additional, Flor Oncala, Maria Jose, additional, Martin, Carlos Gomez, additional, Lopez, Rafael, additional, Muñoz, Andres, additional, Garcia, Ruth Vera, additional, Ales, Inmaculada, additional, Sáez, Berta Laquente, additional, Rivera, Fernando, additional, Sastre, Javier, additional, Wu, Cheng-Chung, additional, Tien, Yu-Wen, additional, Chan, De-Chuan, additional, Hwang, Tsann-Long, additional, Evans, Jeffry, additional, Wadsley, Jonathan, additional, Corrie, Pippa, additional, Biankin, Andrew, additional, Ko, Andrew, additional, Cardin, Dana, additional, Chiorean, Elena, additional, Bendell, Johanna, additional, Noonan, Anne, additional, Kindler, Hedy, additional, Fernando, Nishan, additional, Beg, Muhammad, additional, George, Thomas, additional, Noel, Marcus, additional, LoConte, Noelle, additional, Arena, Francis, additional, Posey, James, additional, Malhotra, Rajat, additional, Lopez, Charles, additional, Sohal, Davendra, additional, McWilliams, Robert, additional, Brenner, Warren, additional, Womack, Mark, additional, Seth, Rahul, additional, lyer, Renuka, additional, Bahary, Nathan, additional, Marsh, Robert, additional, Ramirez, Robert, additional, Chua, Cynthia, additional, Reeves, James, additional, Manji, Gulam, additional, El-Khoueiry, Anthony, additional, Weaver, Robert, additional, Sahai, Vaibhav, additional, Messersmith, Wells, additional, Dreicer, Robert, additional, Zakari, Ahmed, additional, Bullock, Andrea, additional, Musher, Benjamin, additional, Borad, Mitesh, additional, Kim, Edward, additional, Bajor, David, additional, Huyck, Tim, additional, Hatoum, Hassan, additional, Xiong, Henry, additional, Pasche, Boris, additional, Lacy, Jill, additional, Olowokure, Olugbenga, additional, Cohn, Allen, additional, Richards, Donald, additional, Martin, Robert, additional, Paulson, Andrew, additional, Fanta, Paul, additional, Krishnamurthi, Smitha, additional, Oberstein, Paul, additional, and Fuloria, Jyotsna, additional

Published
2023
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44. Supplementary Tables 1-5 from Repurposing Itraconazole and Hydroxychloroquine to Target Lysosomal Homeostasis in Epithelial Ovarian Cancer

Author

Marastoni, Stefano, primary, Madariaga, Ainhoa, primary, Pesic, Aleksandra, primary, Nair, Sree Narayanan, primary, Li, Zhu Juan, primary, Shalev, Zvi, primary, Ketela, Troy, primary, Colombo, Ilaria, primary, Mandilaras, Victoria, primary, Cabanero, Michael, primary, Bruce, Jeff P., primary, Li, Xuan, primary, Garg, Swati, primary, Wang, Lisa, primary, Chen, Eric X., primary, Gill, Sarbjot, primary, Dhani, Neesha C., primary, Zhang, Wenjiang, primary, Pintilie, Melania, primary, Bowering, Valerie, primary, Koritzinsky, Marianne, primary, Rottapel, Robert, primary, Wouters, Bradly G., primary, Oza, Amit M., primary, Joshua, Anthony M., primary, and Lheureux, Stephanie, primary

Published
2023
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45. Data from Repurposing Itraconazole and Hydroxychloroquine to Target Lysosomal Homeostasis in Epithelial Ovarian Cancer

Author

Marastoni, Stefano, primary, Madariaga, Ainhoa, primary, Pesic, Aleksandra, primary, Nair, Sree Narayanan, primary, Li, Zhu Juan, primary, Shalev, Zvi, primary, Ketela, Troy, primary, Colombo, Ilaria, primary, Mandilaras, Victoria, primary, Cabanero, Michael, primary, Bruce, Jeff P., primary, Li, Xuan, primary, Garg, Swati, primary, Wang, Lisa, primary, Chen, Eric X., primary, Gill, Sarbjot, primary, Dhani, Neesha C., primary, Zhang, Wenjiang, primary, Pintilie, Melania, primary, Bowering, Valerie, primary, Koritzinsky, Marianne, primary, Rottapel, Robert, primary, Wouters, Bradly G., primary, Oza, Amit M., primary, Joshua, Anthony M., primary, and Lheureux, Stephanie, primary

Published
2023
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46. Supplementary Materials and Methods from Repurposing Itraconazole and Hydroxychloroquine to Target Lysosomal Homeostasis in Epithelial Ovarian Cancer

Author

Marastoni, Stefano, primary, Madariaga, Ainhoa, primary, Pesic, Aleksandra, primary, Nair, Sree Narayanan, primary, Li, Zhu Juan, primary, Shalev, Zvi, primary, Ketela, Troy, primary, Colombo, Ilaria, primary, Mandilaras, Victoria, primary, Cabanero, Michael, primary, Bruce, Jeff P., primary, Li, Xuan, primary, Garg, Swati, primary, Wang, Lisa, primary, Chen, Eric X., primary, Gill, Sarbjot, primary, Dhani, Neesha C., primary, Zhang, Wenjiang, primary, Pintilie, Melania, primary, Bowering, Valerie, primary, Koritzinsky, Marianne, primary, Rottapel, Robert, primary, Wouters, Bradly G., primary, Oza, Amit M., primary, Joshua, Anthony M., primary, and Lheureux, Stephanie, primary

Published
2023
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47. Supplementary File 2 from Repurposing Itraconazole and Hydroxychloroquine to Target Lysosomal Homeostasis in Epithelial Ovarian Cancer

Author

Marastoni, Stefano, primary, Madariaga, Ainhoa, primary, Pesic, Aleksandra, primary, Nair, Sree Narayanan, primary, Li, Zhu Juan, primary, Shalev, Zvi, primary, Ketela, Troy, primary, Colombo, Ilaria, primary, Mandilaras, Victoria, primary, Cabanero, Michael, primary, Bruce, Jeff P., primary, Li, Xuan, primary, Garg, Swati, primary, Wang, Lisa, primary, Chen, Eric X., primary, Gill, Sarbjot, primary, Dhani, Neesha C., primary, Zhang, Wenjiang, primary, Pintilie, Melania, primary, Bowering, Valerie, primary, Koritzinsky, Marianne, primary, Rottapel, Robert, primary, Wouters, Bradly G., primary, Oza, Amit M., primary, Joshua, Anthony M., primary, and Lheureux, Stephanie, primary

Published
2023
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48. Supplementary File 1 from Repurposing Itraconazole and Hydroxychloroquine to Target Lysosomal Homeostasis in Epithelial Ovarian Cancer

Author

Marastoni, Stefano, primary, Madariaga, Ainhoa, primary, Pesic, Aleksandra, primary, Nair, Sree Narayanan, primary, Li, Zhu Juan, primary, Shalev, Zvi, primary, Ketela, Troy, primary, Colombo, Ilaria, primary, Mandilaras, Victoria, primary, Cabanero, Michael, primary, Bruce, Jeff P., primary, Li, Xuan, primary, Garg, Swati, primary, Wang, Lisa, primary, Chen, Eric X., primary, Gill, Sarbjot, primary, Dhani, Neesha C., primary, Zhang, Wenjiang, primary, Pintilie, Melania, primary, Bowering, Valerie, primary, Koritzinsky, Marianne, primary, Rottapel, Robert, primary, Wouters, Bradly G., primary, Oza, Amit M., primary, Joshua, Anthony M., primary, and Lheureux, Stephanie, primary

Published
2023
Full Text
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49. Supplementary Figures 1-7 from Repurposing Itraconazole and Hydroxychloroquine to Target Lysosomal Homeostasis in Epithelial Ovarian Cancer

Author

Marastoni, Stefano, primary, Madariaga, Ainhoa, primary, Pesic, Aleksandra, primary, Nair, Sree Narayanan, primary, Li, Zhu Juan, primary, Shalev, Zvi, primary, Ketela, Troy, primary, Colombo, Ilaria, primary, Mandilaras, Victoria, primary, Cabanero, Michael, primary, Bruce, Jeff P., primary, Li, Xuan, primary, Garg, Swati, primary, Wang, Lisa, primary, Chen, Eric X., primary, Gill, Sarbjot, primary, Dhani, Neesha C., primary, Zhang, Wenjiang, primary, Pintilie, Melania, primary, Bowering, Valerie, primary, Koritzinsky, Marianne, primary, Rottapel, Robert, primary, Wouters, Bradly G., primary, Oza, Amit M., primary, Joshua, Anthony M., primary, and Lheureux, Stephanie, primary

Published
2023
Full Text
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50. Clinical Trial Protocol from Repurposing Itraconazole and Hydroxychloroquine to Target Lysosomal Homeostasis in Epithelial Ovarian Cancer

Author

Marastoni, Stefano, primary, Madariaga, Ainhoa, primary, Pesic, Aleksandra, primary, Nair, Sree Narayanan, primary, Li, Zhu Juan, primary, Shalev, Zvi, primary, Ketela, Troy, primary, Colombo, Ilaria, primary, Mandilaras, Victoria, primary, Cabanero, Michael, primary, Bruce, Jeff P., primary, Li, Xuan, primary, Garg, Swati, primary, Wang, Lisa, primary, Chen, Eric X., primary, Gill, Sarbjot, primary, Dhani, Neesha C., primary, Zhang, Wenjiang, primary, Pintilie, Melania, primary, Bowering, Valerie, primary, Koritzinsky, Marianne, primary, Rottapel, Robert, primary, Wouters, Bradly G., primary, Oza, Amit M., primary, Joshua, Anthony M., primary, and Lheureux, Stephanie, primary

Published
2023
Full Text
View/download PDF

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