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8. Thyroid Eye Disease: Multidisciplinary Management of Ocular Surface Disease and Considerations for Cataract/Refractive Surgery.

Author

Beckman, Kenneth A., Dhaliwal, Deepinder K., and Lee, Wendy W.

Subjects
*THYROID eye disease, *INSULIN-like growth factor receptors, *SOMATOMEDIN C, *BLEPHAROPTOSIS, *HEALTH & Nutrition Examination Survey, *INFLAMMATORY bowel diseases, *OPHTHALMIC plastic surgery
Abstract

The article delves into the management of thyroid eye disease (TED) and its connection to ocular surface disease (OSD), stressing the importance of recognizing TED in patients with dry eye disease (DED) and OSD for better outcomes. It covers the relationship between TED and other ocular conditions, differential diagnoses, and treatment options like teprotumumab. The document underscores the necessity of proper treatment and collaboration across disciplines for positive patient results, offering a detailed look at TED, its management, and quality of life considerations in the United States. It also touches on the efficacy and safety of teprotumumab, phenylephrine hydrochloride solution, its impact on upper eyelids, and its role in testing for ptosis, as well as the link between thyroid eye disease and conditions like myasthenia gravis. [Extracted from the article]

Published
2024

16. A rise in the frequency of lasR mutant Pseudomonas aeruginosa among keratitis isolates between 1993 and 2021

Author

Shanks, Robert M. Q., primary, Atta, Sarah, additional, Stella, Nicholas A., additional, Sundar-Raj, Chollapadi V., additional, Romanowski, John E., additional, Grewal, Arman S., additional, Shanks, Hazel Q., additional, Mumper, Sonya M., additional, Dhaliwal, Deepinder K., additional, Mammen, Alex, additional, Callaghan, Jake D., additional, Calvario, Rachel C., additional, Romanowski, Eric G., additional, Kowalski, Regis P., additional, Zegans, Michael E., additional, and Jhanji, Vishal, additional

Published
2023
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21. Rise in frequency of lasR mutant Pseudomonas aeruginosa among keratitis isolates between 1993 and 2021

Author

Shanks, Robert MQ, primary, Atta, Sarah, additional, Stella, Nicholas A, additional, Sundar-Raj, Chollapadi V, additional, Romanowski, John E, additional, Grewal, Arman S., additional, Shanks, Hazel Q, additional, Mumper, Sonya M, additional, Dhaliwal, Deepinder K, additional, Mammen, Alex, additional, Callaghan, Jake D, additional, Calvario, Rachel C, additional, Romanowski, Eric G., additional, Kowalski, Regis P, additional, Zegans, Michael E, additional, and Jhanji, Vishal, additional

Published
2023
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22. Surgical correction of presbyopia

Author

Davidson, Richard S., Dhaliwal, Deepinder, Hamilton, D. Rex, Jackson, Mitchell, Patterson, Larry, Stonecipher, Karl, Yoo, Sonia H., Braga-Mele, Rosa, and Donaldson, Kendall

Published
2016
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25. Reply

Author

Huang, Marshall J., Kane, Steven, and Dhaliwal, Deepinder K.

Published
2019
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26. Demodex Blepharitis: A Comprehensive Review of the Disease, Current Management, and Emerging Therapies

Author

Rhee, Michelle K., Yeu, Elizabeth, Barnett, Melissa, Rapuano, Christopher J., Dhaliwal, Deepinder K, Nichols, Kelly K., Karpecki, Paul, Mah, Francis S., Chan, Arthur, Mun, James, Gaddie, Ian Benjamin, Rhee, Michelle K., Yeu, Elizabeth, Barnett, Melissa, Rapuano, Christopher J., Dhaliwal, Deepinder K, Nichols, Kelly K., Karpecki, Paul, Mah, Francis S., Chan, Arthur, Mun, James, and Gaddie, Ian Benjamin

Abstract

Demodex blepharitis is a common disease of the eyelid, affecting approximately 25 million Americans. This article reviews what is known about the mechanisms and impact of Demodex blepharitis, risk factors, signs and symptoms, diagnostic techniques, current management options, and emerging treatments. Demodex mites contribute to blepharitis in several ways: direct mechanical damage, as a vector for bacteria, and by inducing hypersensitivity and inflammation. Risk factors for Demodex blepharitis include increasing age, rosacea, and diabetes. The costs, symptom burden, and psychosocial effects of Demodex blepharitis are considerable. The presence of collarettes is pathognomonic for Demodex blepharitis. Redness, dryness, discomfort, foreign body sensation, lash anomalies, and itching are also hallmarks of the disease. Although a number of oral, topical, eyelid hygiene and device-based options have been used clinically and evaluated in studies for the management of Demodex blepharitis, none have been FDA approved to treat the disease. Recent randomized controlled clinical trials suggest that lotilaner ophthalmic solution, 0.25%, is a topical treatment with the potential to eradicate Demodex mites and eliminate collarettes and eyelid redness for an extended period.

Published
2023

28. Contributors

Author

Afshari, Natalie A., Agarwal, Kanika, Ahmed, Tasnia, Al-Mohtaseb, Zaina, Ayres, Brandon D., Beazer, Alex P., Brooks, Cassandra C., Chamberlain, Winston, Chen, Lauren, Ciralsky, Jessica Blair, Dhaliwal, Deepinder Kaur, Djalilian, Ali R., Donaldson, Kendall E., Farid, Marjan, Gupta, Preeya K., Jhanji, Vishal, Knezevic, Alexander, Koch, Douglas D., Lin, Amy, Mah, Francis S., Majmudar, Parag A., Majmudar, Shivani, Meghpara, Beeran B., Mittal, Aman, Moussa, Kareem, Nakatsuka, Austin S., Pflugfelder, Stephen C., Pollard, Margaret C., Rapuano, Christopher J., Rhee, Michelle K., Rosenberg, Eric, Schallhorn, Julie Marie, Seo, Kyoung Yul, Shen, Elizabeth, Smith, Ryan G., Starnes, Taylor W., Stutzman, Richard, Sundararajan, Miel, Syed, Zeba A., Tu, Elmer Y., Vaidya, Neel, Wade, Matthew, Wang, Yvonne, Xie, Kate, and Yeu, Elizabeth

Published
2025
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32. Food and Drug Administration, American Academy of Ophthalmology, American Academy of Optometry, American Association for Pediatric Ophthalmology and Strabismus, American Optometric Association, American Society of Cataract and Refractive Surgery, and Contact Lens Association of Ophthalmologists Co-Sponsored Workshop: Controlling the Progression of Myopia: Contact Lenses and Future Medical Devices

Author

Walline, Jeffrey J., Robboy, Marc W., Hilmantel, Gene, Tarver, Michelle E., Afshari, Natalie A., Dhaliwal, Deepinder K., Morse, Christie L., Quinn, Christopher J., Repka, Michael X., and Eydelman, Malvina B.

Published
2018
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35. Cost Burden of Endothelial Keratoplasty in Fuchs Endothelial Dystrophy: Real-World Analysis of a Commercially Insured US Population (2014–2019)

Author

Dhaliwal,Deepinder K, Chirikov,Viktor, Schmier,Jordana, Rege,Sanika, Newton,Schalon, Dhaliwal,Deepinder K, Chirikov,Viktor, Schmier,Jordana, Rege,Sanika, and Newton,Schalon

Abstract

Deepinder K Dhaliwal,1 Viktor Chirikov,2 Jordana Schmier,2 Sanika Rege,2 Schalon Newton3 1Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; 2OPEN Health Evidence & Access, Bethesda, MD, USA; 3Trefoil Therapeutics, Inc., San Diego, CA, USACorrespondence: Schalon Newton, Trefoil Therapeutics, Inc., 6330 Nancy Ridge Dr Suite 103, San Diego, CA, 92121, USA, Tel +1 949 678 9572, Email snewton@trefoiltherapeutics.comPurpose: To assess the incremental burden of corneal transplant surgery for US commercially insured patients with Fuchs endothelial corneal dystrophy (FECD) treated with endothelial keratoplasty (EK) compared to controls.Methods: The study design was retrospective cohort using IBM® MarketScan® claims (January 2014–September 2019) and included EK-treated (N=1562) and control patients (N=23,485) having ≥ 12 months’ enrollment before and after diagnosis, who were subsequently matched on select characteristics. The index date was the beginning of the pre-operative period (3 months before EK); synthetic EK index was assigned for controls. All-cause, eye-disease, and complication-related healthcare resource utilization (HCRU) and costs were compared up to 36 months post index. For a small subset of patients, patient data were linked to the Health and Productivity Management supplemental database, which integrates data on productivity loss and disability payments.Results: Matched cohorts included 804 EK-treated and 1453 controls with average age 65.7 years, 1383 (61%) female. Over 12 months of follow-up, all-cause ($41,199 vs $20,222, p< 0.001) and eye-disease related costs ($22,951 vs $1389, p< 0.001) were higher among EK-treated patients than controls. The cost differential increased additionally by $1000–$2000 per annum by 36 months of follow-up. While balanced at baseline, over follow-up EK-treated patients had higher prevalence of glaucoma, elevated intraocular pressure, cataract, cataract surgery

Published
2022

36. This month's case: cataract surgery in a patient with keratoconus

Author

Sheppard, John, Aldave, Anthony J., Dhaliwal, Deepinder K., Henderson, Bonnie An, Pepose, Jay S., and Trattler, William B.

Subjects
Diagnosis, Care and treatment, Patient outcomes, Methods, Cataract extraction -- Methods -- Patient outcomes, Keratoconus -- Diagnosis -- Care and treatment, Cataract -- Surgery
Abstract

Case from the files of John Sheppard, MD, MMSc A 51-year-old man with a 20-year history of keratoconus presents with complaints of glare and decreased vision. The glare first developed [...]

Published
2016

43. DemodexBlepharitis: A Comprehensive Review of the Disease, Current Management, and Emerging Therapies

Author

Rhee, Michelle K., Yeu, Elizabeth, Barnett, Melissa, Rapuano, Christopher J., Dhaliwal, Deepinder K., Nichols, Kelly K., Karpecki, Paul, Mah, Francis S., Chan, Arthur, Mun, James, and Gaddie, Ian Benjamin

Abstract

Demodexblepharitis is a common disease of the eyelid, affecting approximately 25 million Americans. This article reviews what is known about the mechanisms and impact of Demodexblepharitis, risk factors, signs and symptoms, diagnostic techniques, current management options, and emerging treatments. Demodexmites contribute to blepharitis in several ways: direct mechanical damage, as a vector for bacteria, and by inducing hypersensitivity and inflammation. Risk factors for Demodexblepharitis include increasing age, rosacea, and diabetes. The costs, symptom burden, and psychosocial effects of Demodexblepharitis are considerable. The presence of collarettes is pathognomonic for Demodexblepharitis. Redness, dryness, discomfort, foreign body sensation, lash anomalies, and itching are also hallmarks of the disease. Although a number of oral, topical, eyelid hygiene and device-based options have been used clinically and evaluated in studies for the management of Demodexblepharitis, none have been FDA approved to treat the disease. Recent randomized controlled clinical trials suggest that lotilaner ophthalmic solution, 0.25%, is a topical treatment with the potential to eradicate Demodexmites and eliminate collarettes and eyelid redness for an extended period.

Published
2023
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44. Colaboradores

Author

Abtahi, Maryam, Adams, Wendy, Afshari, Natalie A., Agarwal, Anita, Agranat, Joshua S., Ajlan, Radwan S., Akhlaq, Anam, Al-Aswad, Lama, AlBayyat, Ghada, Albini, Thomas A., -Ghoul, Ahmed Al, Al-Mohtaseb, Zaina, Alvi, Nishat P., Apple, David J., Aquino, Maria Cecilia, Arnold, Anthony C., Arnoldi, Kyle, Arshinoff, Steve A., Asbell, Penny A., Ashe, Stephen A., Asroui, Lara, Atebara, Neal H., Awh, Katherine C., Aylward, G. William, Bacci, Tommaso, Bakri, Sophie J., Balcer, Laura J., Balducci, Nicole, Barboni, Piero, Baş, Zeynep, Basu, Soumyava, Baumal, Caroline R., Bessette, Angela P., Bhatt, Nirali, Bhullar, Paramjit K., Binotti, William, Birch, Eileen E., Biswas, Jyotirmay, Bjerregaard, Robert William, Bose, Swaraj, Bouchard, Charles S., Boulton, Michael E., Bouremel, Yann, Brandt, James D., Brocchini, Steve, Brodie, Scott E., Brodsky, Michael C., Brooks, Cassandra, Brown, Aaron Christopher, Budenz, Donald L., Cantor, Louis B., Capo, Hilda, Capone, Antonio, Jr, Carruthers, Alastair, Carruthers, Jean D., Carter, Keith D., Chahal, Harinderpal, Chan, Chi-Chao, Chan, Jane W., Chang, Melinda Y., Chang, Stanley, Charteris, David G., Chee, Soon-Phaik, Chen, Masako, Chen, Michael Yipeng, Chen, Sien, Chen, Xuejing, Chew, Paul Tec Kuan, Chong, Jillian K., Chow, Clement C., Clarke, Jonathan C.K., Codère, François, Conner, Ian P., Cortina, Maria Soledad, Couch, Steven M., Coupland, Stuart G., Cowan, Claude, Jr, Craven, E. Randy, Cukras, Catherine A., Dagi, Linda, Dalvin, Lauren A., Damgaard, Iben Bach, Damji, Karim Fatehali, Das, Dipankar, DeBusk, Adam, de Carlo, Talisa E., Coulon, Sara Jacob, Demer, Joseph Louis, Desai, Shilpa J., Dhaliwal, Deepinder K., Dhawlikar, Nisha, Diamond, Gary R., Diaz, Jose Daniel, Diniz, Daniel, Djenderedjian, Levon, Do, Anna Thanh Tam, Do, Diana V., Dolman, Peter J., Donahue, Sean P., Drenser, Kimberly A., Duffy, Kevin R., Duker, Jacob S., Duker, Jay S., Dupps, William J., Jr, Durairaj, Vikram D., Dutton, Jonathan J., Eliott, Dean, Engelbert, Michael, Enzor, Rikki S., Epstein, Aliza, Evans, Joshua W., Evans, Monica, Faia, Lisa J., Fallano, Katherine A., Farjo, Ayad A., Fernandez, Karen B., Fisher, Yale L., Fortun, Jorge A., Friedman, Deborah I., Friedman, Neil J., Fynn-Thompson, Nicoletta, Gadaria-Rathod, Neha, Garg, Sumit (Sam), Gayre, Gregg, Gedde, Steven, Geevarghese, Alexi, Ghosh, Saurabh, Gigantelli, James William, Goerlitz-Jessen, Mark, Goldberg, Ivan, Goldberg, Jeffrey L., Goldstein, Debra A., Goldstein, Michael H., Gonzales, John A., Gore, Charlotte, Granet, David B., Greven, Craig M., Greven, Margaret A., Gross, Ronald L., Gündüz, Ahmet Kaan, Gupta, Preeya K., Haller, Julia A., Hamrah, Pedram, Hannush, Sadeer B., Hardin, Joshua S., Harris, Alon, Hassan, Muhammad, Heier, Jeffrey S., Herndon, Leon W., Ho, Allen C., Ho, Joanne W., Honasoge, Avinash, Hood, Christopher T., Houghton, Odette, Houser, Kourtney, Howes, Frank W., Hsu, Jason, Hurwitz, Jeffrey J., Irochima, Francisco, Isteitiya, Jihad, Iyer, Geetha, Izak, Andrea M., Jackson, Kevin, Jacob, Soosan, Jacoba, Cris Martin P., Jacobs, Deborah S., Jampel, Henry D., Jampol, Lee M., Jeng-Miller, Karen, Chen, John Jing-Wei, Johnson, Mark W., Johnson, T. Mark, Johnstone, Murray, Kaakour, Abdul-Hadi, Kaehr, Mark M., Kahook, Malik Y., Kaiser, Peter K., Kalafatis, Nicholas, Kalevar, Ananda, Kane, Steven, Kang, Kai, Kanner, Elliott M., Kapoor, Saloni, Kapusta, Michael Alton, Karanjia, Rustum, Kardon, Randy H., Karp, Carol L., Kashani, Amir H., Kass, Michael A., Kataguiri, Paula, Kaufman, Paul L., Keenan, Jeremy D., Kelly, Elaine, Kenyon, Kenneth R., Khandelwal, Sumitra, Khaw, Peng Tee, Kim, Ivana K., Kim, Terry, Kinori, Michael, Kiss, Szilárd, Kitchens, John W., Klein, Kendra, Ko, Narae, Koch, Douglas D., Kodati, Shilpa, Koh, Victor, Kohnen, Thomas, Konstas, Angelos A., Koo, Ellen, Lane, Stephen S., Lavin, Patrick J.M., Lavinsky, Fabio, Lawton, Andrew W., Le, Nhon T., Lee, Bonny, Lee, Crystal, Lee, Gregory D., Lee, Paul P, Lee, Rachel Han, Lim, Dawn Ka Ann, Lin, Tony, Lind, John T., Liu, Dan, Liu, Yao, Liyanage, Sidath E., Longmuir, Reid A., Lundström, Mats, Maamari, Robi N., Mahjoub, Heba, Maloney, Maya H., Mamalis, Christina, Manche, Edward E., Mandava, Naresh, Martheswaran, Tanisha, Masket, Samuel, Mattox, Cynthia, McClatchey, Scott Kevin, McLeod, Stephen D., McMillan, Brian D., McNab, Alan A., Mehra, Ankur, Mehta, Jodhbir S., Mejia-Vergara, Alvaro J., Mejico, Luis J., Mekhail, Joseph, Mercer, Ryan N., Mian, Shahzad I., Mieler, William F., Miller, Kyle E., Mirza, Rukhsana G., Misra, Poonam, Mititelu, Mihai, Mohammed, Taariq, Moorthy, Ramana S., Morkin, Melina I., Moshfeghi, Andrew A., Moshirfar, Majid, Moss, Heather E., Moster, Mark L., Muhtaseb, Ruba, Muir, Kelly W., Neff, Ann G., Nerad, Jeffrey A., Ng, Caleb C., Nguyen, Annie, Nikpoor, Neda, Nosé, Ricardo, Okada, Annabelle A., O’Keefe, Ghazala A. Datoo, Olson, Jeffrey L., Olver, Jane M., Örge, Faruk H., Packard, Richard, Packer, Mark, Panarelli, Joseph, Pandey, Suresh K., Parikh, Vishal S., Pasha, Hamza, Pasquale, Louis R., Patel, Palak, Patel, Sarju S., Patel, Shaila R., Patel, Vivek R., Pavesio, Carlos, Perez, Victor L., Phillips, Lauren T., Piltz-Seymour, Jody R., Piva, Alfio P., Presland, Andrew H., Price, Francis W., Jr, Price, Marianne O., Quiros, Peter A., Rachitskaya, Aleksandra, Rahmani, Safa, Ramulu, Pradeep Y., Randleman, J. Bradley, Rao, Narsing A., Rao, Naveen K., Rao, P. Kumar, Rao, Rajesh C., Rathinam, Sivakumar, Read, Russell W., Reed, Donovan, Regatieri, Caio Vinícius Saito, Regillo, Carl D., Reichel, Elias, Reighard, Chelsea L., Richard, Alyse, Ringeisen, Alexander, Ritch, Robert, Robbins, Shira L., Rocha, Karolinne M., Rodger, Damien C., Roh, Miin, Rosado-Adames, Noel, Rowe, Lucas W., Rubenstein, Jonathan B., Rubin, Richard M., Rubsamen, Patrick E., Saadati, Hossein G., Sadun, Alfredo A., Saeedi, Osamah, Sajjad, Ahmar, Salchow, Daniel J., Salim, Sarwat, Salongcay, Recivall P., Sandhu, Simrenjeet, Santhiago, Marcony R., Satija, Celine E., Schallhorn, Julie M., Schmitt, Melanie, Schor, Paulo, Schroeder, Richard, Schubert, Hermann D., Schuman, Joel S., Schwartz, Gary S., Sen, H. Nida, Shah, Gaurav K., Shah, Ravi, Shields, Carol L., Shields, Jerry A., Shildkrot, Yevgeniy (Eugene), Shingleton, Bradford J., Shtein, Roni M., Chan, Nicole Shu-Wen, Shultz, Ryan W., Sieck, Erin, Siesky, Brent, Sieving, Paul A., Silva, Paolo S., Simmons, Kirsten, Skondra, Dimitra, Smiddy, William E., Somogyi, Marie, Soong, H. Kaz, Soukiasian, Sarkis H., Spoor, Thomas C., Srinivasan, Bhaskar, Srivastava, Sunil K., Starnes, Taylor W., Starr, Matthew R., Steel, David H., Steigleman, W. Allan, Stein, Joshua D., Stepien, Kimberly E., Stevens, Dylan V., Strominger, Mitchell B., Sugar, Alan, Sugar, Joel, Suh, Donny W., Sun, Michelle, Sun, Yang, Sychev, Yevgeniy V., Tai, Tania, Tan, James C., Tanenbaum, Myron, Tasman, William, Tassignon, Marie-José B., Testi, Ilaria, Thall, Edmond H., Thanos, Aristomenis, Theophanous, Christos N., Thornton, Sarah, Tingey, David P., Todorich, Bozho, Tompson, Stuart W., Toy, Brian, Tsai, James C., Tsai, Julie, Tucker, Nancy, Tuli, Sonal S., Valerio, Gabriel S., Vargason, Caroline W., Vasaiwala, Roshni A., Vasconcelos-Santos, Daniel Vitor, Vaughn, Gregory J., Venkateswaran, Nandini, Vinod, Kateki, Vislisel, Jesse M., Vrcek, Ivan, Walton, David S., Wang, Li, Wang, Michelle Y., Wang, Robert C., Waring, George O., IV, Weikert, Mitchell P., Werner, Liliana, Wevill, Mark, Wiggs, Janey L., Williams, Andrew M., Williams, George A., Witmer, Matthew T., Wollstein, Gadi, Woodward, Maria A., Wride, Nicholas K., Wu, Albert Y., Yaghy, Antonio, Young, Joshua A., Zaguia, Fatma, Zein, Wadih M., and Zhu, Ivy

Published
2024
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