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Various complications of atropine therapy in cases of organophosphorus poisoning have been reported. Among them, atropine induced paralytic ileus is a serious gastrointestinal complication with very few cases published worldwide. The tendency of over atropinization in organophosphorus poisoning despite regular monitoring is common and may develop life threatening complications as well. This necessitates knowledge, thorough examination, and an experienced approach to aid in treatment and complications management. We have discussed a case of organophosphorus poisoning, with symptoms of atropine toxicity and acute abdominal complication treated with surgical approach in our setting. [ABSTRACT FROM AUTHOR]

INTRODUCTION The burden of type 2 diabetes is increasing in world and same is scenario in Nepal. The prevalence of T2DM in Nepal has increased from 2014 to 2020. T2DM is still a major cause of worldwide morbidity and mortality, due to its complications. A strong correlation between cardiovascular diseases and diabetes mellitus type 2 (DM) has been found. This study aimed to investigate echocardiographic features and clinical profile in patients with newly diagnosed T2DM. MATERIAL AND METHODS Our study included 100 patients with newly diagnosed type 2 diabetes, presented to Medicine Department of Universal College of Medical Sciences Teaching Hospital, Bhairahawa from 1st May, 2019 AD to 30th April 2020. We included type 2 diabetes diagnosed as per American diabetes association 2018 criteria. RESULTS Males (52%) were more compared to females (44%). 28% were in age group 61-70 years, 26% in age group 41-50 years and 25% in age group 51-60 years. Abnormal thirst 42%, polyuria 38% and weight loss 32% were most common presenting symptoms with 23% having all 3 symptoms. Fifty two percent were smokers, 22% consumed alcohol, 48% had HTN and 23% cases had CAD. Fourty two cases (42%) had Left ventricular diastolic dysfunction, 25 cases (25%) had Left ventricular hypertrophy (LVH), 16 cases (16%) had RWMA others had RA/RV dilated and dilated LV/LA. CONCLUSION LVDD was most common echocardiographic finding in newly diagnosed type 2 diabetes. [ABSTRACT FROM AUTHOR]

INTRODUCTION Corona virus disease 2019 (COVID-19) has become a global public health issue with unpredictable progression to ARDS. Therapy timing of anti-inflammatory agents and immune-suppressing medication is of utmost importance. Previous studies have consistently found elevated levels of C-Reactive Protein with disease severity. In this study, we aimed to investigate the relationship between C-Reactive Protein and severe SARS-COV-2 pneumonia. MATERIAL AND METHODS Our study included 55 patients with COVID-19, admitted in COVID Unit of Universal College of Medical Sciences Teaching Hospital (UCMS-TH), Bhairahawa, Rupandehi, Nepal from 16 June 2021 to 15 September 2021. We included COVID-19 cases confirmed by a RT-PCR test with severe pneumonia based on WHO criteria and those undergoing Creactive protein levels. RESULTS Males (56%) were more compared to females (44%). Age group 41-60 years were likely to develop severe COVID-19 pneumonia. Cough (44%), dyspnea (42%) and fever (40%) were most common symptom. Hypertension (34%) and diabetis (24%) were common comorbidities present. Patients with severe COVID-19 pneumonia had average CRP value of 59.6 mg/l. CONCLUSION Elevated CRP level was associated with COVID-19 severity. [ABSTRACT FROM AUTHOR]