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41 results on '"Desperito, Elise"'

2. Radiology of fibrosis part III: genitourinary system

Author

Tarchi, Sofia Maria, Salvatore, Mary, Lichtenstein, Philip, Sekar, Thillai, Capaccione, Kathleen, Luk, Lyndon, Shaish, Hiram, Makkar, Jasnit, Desperito, Elise, Leb, Jay, Navot, Benjamin, Goldstein, Jonathan, Laifer, Sherelle, Beylergil, Volkan, Ma, Hong, Jambawalikar, Sachin, Aberle, Dwight, D’Souza, Belinda, Bentley-Hibbert, Stuart, and Marin, Monica Pernia

Published
2024
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3. Radiology of fibrosis. Part I: Thoracic organs

Author

Tarchi, Sofia Maria, Salvatore, Mary, Lichtenstein, Philip, Sekar, Thillai, Capaccione, Kathleen, Luk, Lyndon, Shaish, Hiram, Makkar, Jasnit, Desperito, Elise, Leb, Jay, Navot, Benjamin, Goldstein, Jonathan, Laifer, Sherelle, Beylergil, Volkan, Ma, Hong, Jambawalikar, Sachin, Aberle, Dwight, D’Souza, Belinda, Bentley-Hibbert, Stuart, and Marin, Monica Pernia

Published
2024
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4. Radiology of fibrosis part II: abdominal organs

Author

Tarchi, Sofia Maria, Salvatore, Mary, Lichtenstein, Philip, Sekar, Thillai, Capaccione, Kathleen, Luk, Lyndon, Shaish, Hiram, Makkar, Jasnit, Desperito, Elise, Leb, Jay, Navot, Benjamin, Goldstein, Jonathan, Laifer, Sherelle, Beylergil, Volkan, Ma, Hong, Jambawalikar, Sachin, Aberle, Dwight, D’Souza, Belinda, Bentley-Hibbert, Stuart, and Marin, Monica Pernia

Published
2024
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7. Dynamic Changes of Convolutional Neural Network-based Mammographic Breast Cancer Risk Score Among Women Undergoing Chemoprevention Treatment.

Author

Manley, Haley, Mutasa, Simukayi, Chang, Peter, Desperito, Elise, Crew, Katherine, and Ha, Richard

Subjects
Breast cancer risk, Breast density, CNN, Deep learning, Tamoxifen, Adult, Aged, Aged, 80 and over, Antineoplastic Agents, Breast Neoplasms, Carcinoma, Chemoprevention, Female, Humans, Mammography, Middle Aged, Neural Networks, Computer, Predictive Value of Tests, Retrospective Studies, Risk Assessment
Abstract

INTRODUCTION: We investigated whether our convolutional neural network (CNN)-based breast cancer risk model is modifiable by testing it on women who had undergone risk-reducing chemoprevention treatment. MATERIALS AND METHODS: We conducted a retrospective cohort study of patients diagnosed with atypical hyperplasia, lobular carcinoma in situ, or ductal carcinoma in situ at our institution from 2007 to 2015. The clinical characteristics, chemoprevention use, and mammography images were extracted from the electronic health records. We classified two groups according to chemoprevention use. Mammograms were performed at baseline and subsequent follow-up evaluations for input to our CNN risk model. The 2 chemoprevention groups were compared for the risk score change from baseline to follow-up. The change categories included stayed high risk, stayed low risk, increased from low to high risk, and decreased from high to low risk. Unordered polytomous regression models were used for statistical analysis, with P < .05 considered statistically significant. RESULTS: Of 541 patients, 184 (34%) had undergone chemoprevention treatment (group 1) and 357 (66%) had not (group 2). Using our CNN breast cancer risk score, significantly more women in group 1 had shown a decrease in breast cancer risk compared with group 2 (33.7% vs. 22.9%; P < .01). Significantly fewer women in group 1 had an increase in breast cancer risk compared with group 2 (11.4% vs. 20.2%; P < .01). On multivariate analysis, an increase in breast cancer risk predicted by our model correlated negatively with the use of chemoprevention treatment (P = .02). CONCLUSIONS: Our CNN-based breast cancer risk score is modifiable with potential utility in assessing the efficacy of known chemoprevention agents and testing new chemoprevention strategies.

Published
2021

15. Advances in PET/CT Imaging for Breast Cancer

Author

de Jong, Dorine, primary, Desperito, Elise, additional, Al Feghali, Karine A., additional, Dercle, Laurent, additional, Seban, Romain-David, additional, Das, Jeeban P., additional, Ma, Hong, additional, Sajan, Abin, additional, Braumuller, Brian, additional, Prendergast, Conor, additional, Liou, Connie, additional, Deng, Aileen, additional, Roa, Tina, additional, Yeh, Randy, additional, Girard, Antoine, additional, Salvatore, Mary M., additional, and Capaccione, Kathleen M., additional

Published
2023
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19. Abstract B011: Breast cancer worry, uncertainty, and perceived risk following breast density notification in a longitudinal mammography screening cohort vary by educational attainment and dominant language

Author

Argov, Erica J. Lee, primary, Rodriguez, Carmen B., additional, Agovino, Mariangela, additional, Wei, Ying, additional, Shelton, Rachel C., additional, Kukafka, Rita, additional, Schmitt, Karen M., additional, Desperito, Elise, additional, Terry, Mary Beth, additional, and Tehranifar, Parisa, additional

Published
2023
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21. Chest CT for Breast Cancer Diagnosis

Author

Desperito, Elise, primary, Schwartz, Lawrence, additional, Capaccione, Kathleen M., additional, Collins, Brian T., additional, Jamabawalikar, Sachin, additional, Peng, Boyu, additional, Patrizio, Rebecca, additional, and Salvatore, Mary M., additional

Published
2022
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24. Breast Density Awareness and Knowledge in a Mammography Screening Cohort of Predominantly Hispanic Women: Does Breast Density Notification Matter?

Author

Austin, Jessica D., primary, Agovino, Mariangela, additional, Rodriguez, Carmen B., additional, Terry, Mary Beth, additional, Shelton, Rachel C., additional, Wei, Ying, additional, Desperito, Elise, additional, Schmitt, Karen M., additional, Kukafka, Rita, additional, and Tehranifar, Parisa, additional

Published
2021
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31. Utilization of multiple SAVI SCOUT surgical guidance system reflectors in the same breast: A single-institution feasibility study

Author

Jadeja, Priya H., primary, Mango, Victoria, additional, Patel, Sejal, additional, Friedlander, Lauren, additional, Desperito, Elise, additional, Ayala-Bustamante, Everick, additional, Wynn, Ralph, additional, Chen-Seetoo, Margaret, additional, Taback, Bret, additional, Feldman, Sheldon, additional, and Ha, Richard, additional

Published
2017
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33. 2016 RAD-AID Conference on International Radiology for Developing Countries: Gaps, Growth, and United Nations Sustainable Development Goals

Author

Mollura, Daniel J., primary, Soroosh, Garshasb, additional, Culp, Melissa P., additional, Averill, Sarah, additional, Axelrod, David, additional, Baheti, Aparna, additional, Battino, Gillian, additional, Buchanan, Krystal, additional, Bueno, Juliana, additional, Dako, Farouk, additional, Desperito, Elise, additional, DuCharme, Patricia, additional, Elezaby, Mai, additional, Faulkner, Adriana, additional, Foryoung, Kenedy, additional, Garra, Brian, additional, Gerus, Dale, additional, Ghesani, Munir, additional, Gill, Tariq, additional, Hewlett, Vincent, additional, Jeudy, Jean, additional, Kenyon, Thomas A., additional, Kesselman, Andrew, additional, Louden, Connor, additional, Mazal, Jonathan, additional, Minshew, Lindsey, additional, Monchil, Natasha, additional, Morris, Michael, additional, Mollura, Daniel J., additional, Nijssen-Jordan, Cheri, additional, Nisenbaum, Harvey L., additional, Pierce, Bart, additional, Pitcher, Richard, additional, Pollack, Erica, additional, Pollard, Janet, additional, Quansah, Seth, additional, Reiter, Michael, additional, Saboury, Babak, additional, Saling, Lauren, additional, Schmit, Berndt, additional, Schwartz, Matthew, additional, Sobolewski, Robin, additional, Soroosh, Gary, additional, Stephens, Veleda, additional, Sura, Amit, additional, Surujpaul, Petal, additional, Tutone, Eva, additional, Whitlock, Gary, additional, Yannes, Michael, additional, and Zagurovskaya, Marianna, additional

Published
2017
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35. Utilization of multiple SAVI SCOUT surgical guidance system reflectors in the same breast: A single-institution feasibility study.

Author

Jadeja, Priya H., Mango, Victoria, Patel, Sejal, Friedlander, Lauren, Desperito, Elise, Ayala-Bustamante, Everick, Wynn, Ralph, Chen-Seetoo, Margaret, Taback, Bret, Feldman, Sheldon, and Ha, Richard

Subjects
BREAST tumors, RADIOGRAPHY, LUMPECTOMY, RETROSPECTIVE studies, EQUIPMENT & supplies
Abstract

SAVI SCOUT Surgical Guidance System has been shown to be a reliable and safe alternative to wire localization in breast surgery. This study evaluated the feasibility of using multiple reflectors in the same breast. We performed an IRB-approved, HIPAA-compliant, single-institution retrospective review of 183 patients who underwent breast lesion localization and excision using SAVI SCOUT Surgical Guidance System (Cianna Medical) between June 2015 and January 2017. We performed a subset analysis in 42 patients in whom more than one reflector was placed. Specimen radiography, pathology, distance between reflectors, target removal, margin positivity, and complications were evaluated. Among 183 patients, 42 patients had more than one reflector placed in the same breast to localize 68 lesions. Benign (n = 6, 8.8%), high-risk (n = 23, 33.8%), and malignant (n = 39, 57.4%) lesions were included. Thirty-six patients (85.7%) had a total of 2 reflectors placed and 6 patients had a total of 3 reflectors placed (14.3%). The indications for multiple reflector placement in the same breast included multiple separate lesions (n = 23) and bracketing of large lesions (n = 19). The mean distance between the reflectors was 42 mm (22-93 mm). All lesions were successfully targeted and retrieved. Of 39 malignant lesions, 10.3% (n = 4) had positive margins and 10.3% (n = 4) had close (<1 mm) margins at surgery. All patients with positive margins underwent re-excision. No complications occurred preoperatively, intra-operatively, or postoperatively. The use of multiple SAVI SCOUT reflectors for localizing multiple lesions in the same breast or bracketing large lesions is feasible and safe. [ABSTRACT FROM AUTHOR]

Published
2018
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39. Digital optical tomography system for dynamic breast imaging

Author

Flexman, Molly L., primary, Khalil, Michael A., additional, Al Abdi, Rabah, additional, Kim, Hyun K., additional, Fong, Christopher J., additional, Desperito, Elise, additional, Hershman, Dawn L., additional, Barbour, Randall L., additional, and Hielscher, Andreas H., additional

Published
2011
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40. Optical tomographic imaging of the hemodynamic response to a breath hold in breast cancer patients

Author

Flexman, Molly L., Khalil, Michael A., Al Abdi, Rabah M., Reig, Beatriu, Fong, Christopher J., Hershman, Dawn, Desperito, Elise, Barbour, Randall L., and Hielscher, Andreas H.

Abstract

Continuous wave optical tomography is non-ionizing, uses endogenous contrast, and can be performed quickly and at low cost which makes it a suitable imaging modality for breast cancer screening. Using multiple wavelengths of light to illuminate the breast at various angles, three-dimensional images of the distribution of chromophores such as oxy- and deoxy-hemoglobin can help identify cancerous tissue. Dynamic optical imaging can provide additional insight into cancer characteristics such as angiogenesis and metabolism. Here we present the first clinical data acquired with our novel digital breast imaging system. This system is based upon a Digital Signal Processor (DSP) architecture that leverages the immediate digitization of acquired analog data to reduce noise and quickly process large amounts of data. Employing this new instrument we have investigated the dynamic changes due to a breath hold and its potential for use in breast cancer screening. Over the course of a breath hold, images have been collected simultaneously from both breasts at a rate of 1.7 frames per second with 32 sources and 64 detectors per breast and four wavelengths of light at 765, 805, 827, and 905nm. Initial results involving one healthy volunteer and one breast cancer patient support the potential use of dynamic imaging for breast cancer detection.

Published
2011
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41. Can Hounsfield units on chest CT characterize breast nodules as cystic or solid?

Author

Capaccione K, Desperito E, Asiimwe AC, and Salvatore M

Abstract

We report the results of our retrospective analysis of the ability of standard chest computed tomography (CT) scans to correctly differentiate cystic from solid lesions. MModal Catalyst identified 27 women who had an ultrasound of the breast that was recommended because of a chest CT finding between January 1, 2010, and December 31, 2017. All images were reviewed by a radiologist fellowship trained in both breast imaging and cardiothoracic radiology (MS). Ultrasound characterization of lesion density as cystic or solid was considered the gold standard for this study. Analysis of CT scans was performed to identify lesions of interest corresponding to ultrasound abnormality; average, minimum, and maximum Hounsfield units (HUs) were measured. If masses had any solid component, they were considered solid. Twenty masses were solid, and 7 masses were cystic on ultrasound. Thirteen studies were performed without contrast and 14 were performed with contrast. On non-contrast studies, the average HU for cystic lesions was 19 compared to 38 HU for solid (P=0.007). On contrast studies, the average HU for cystic lesions was 16 compared to 53 HU for solid (P=0.002). Cystic lesions did not change with contrast significantly. Solid lesions enhanced with contrast; average HU 38 without contrast to 53 HU with contrast. Chest CT accurately diagnosed breast masses as cystic or solid with or without contrast., Competing Interests: Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://tbcr.amegroups.org/article/view/10.21037/tbcr-23-34/coif). M.S. has received grant funding paid to the hospital, and money for lectures and research paid to her directly. K.C. is an Advisor for Cardinal Health Oncology Summits. The other authors have no conflicts of interest to declare., (2024 Translational Breast Cancer Research. All rights reserved.)

Published
2023
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