25 results on '"Dernovšek, Jaka"'
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2. Exploration and optimisation of structure-activity relationships of new triazole-based C-terminal Hsp90 inhibitors towards in vivo anticancer potency
3. Hiding in plain sight: Optimizing topoisomerase IIα inhibitors into Hsp90β selective binders
4. First dual inhibitors of human topoisomerase IIα and Hsp90 C-terminal domain inhibit the growth of Ewing sarcoma in vitro and in vivo
5. Improved N-phenylpyrrolamide inhibitors of DNA gyrase as antibacterial agents for high-priority bacterial strains
6. Following the design path of isoform-selective Hsp90 inhibitors: Small differences, great opportunities
7. Optimisation of pyrazolo[1,5-a]pyrimidin-7(4H)-one derivatives as novel Hsp90 C-terminal domain inhibitors against Ewing sarcoma
8. Identification of a Novel Structural Class of HV1 Inhibitors by Structure-Based Virtual Screening
9. New Class of Hsp90 C‑Terminal Domain Inhibitors with Anti-tumor Properties against Triple-Negative Breast Cancer.
10. Benzimidazole–galactosides bind selectively to the Galectin-8 N-Terminal domain: Structure-based design and optimisation
11. Discovery of new Hsp90–Cdc37 protein–protein interaction inhibitors: in silico screening and optimization of anticancer activity.
12. New N-phenylpyrrolamide inhibitors of DNA gyrase with improved antibacterial activity.
13. Identification of a Novel Structural Class of HV1 Inhibitors by Structure-Based Virtual Screening.
14. Computer-aided structure-based optimization of 4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine derivatives as DNA gyrase B inhibitors
15. Benzimidazole-galactosides bind selectively to the galectin-8 N-terminal domain
16. New Diarylamine KV10.1 Inhibitors and Their Anticancer Potential
17. In Silico Discovery and Optimisation of a Novel Structural Class of Hsp90 C-Terminal Domain Inhibitors
18. Catalytic Stereoconvergent Synthesis of Homochiral β-CF3, β-SCF3, and β-OCF3 Benzylic Alcohols
19. Homochiral β-CF3, -SCF3 and -OCF3 secondary alcohols: catalytic stereoconvergent synthesis, bioactivity and flexible crystals
20. Design and synthesis of novel 3-triazolyl-1-thiogalactosides as galectin-1, -3 and -8 inhibitors
21. Structure-Activity Relationships of Benzothiazole-Based Hsp90 C-Terminal-Domain Inhibitors
22. New Diarylamine K V 10.1 Inhibitors and Their Anticancer Potential.
23. Načrtovanje, sinteza in vrednotenje 1,4-disubstituiranih-1,2,3-triazolo-galaktozidov kot zaviralcev galektinov-1 in -8
24. Identification of a Novel Structural Class of H V 1 Inhibitors by Structure-Based Virtual Screening.
25. Catalytic Stereoconvergent Synthesis of Homochiral β-CF 3 , β-SCF 3 , and β-OCF 3 Benzylic Alcohols.
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