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1. Ventricular remodeling in a mouse model of myocardial infarction

Author

Patten, Richard D., Aronovitz, Mark J., Deras-Mejia, Luz, Pandian, Natesa G., Hanak, George G., Smith, John J., Mendelsohn, Michael E., and Konstam, Marvin A.

Subjects
Heart ventricles -- Models, Mice -- Physiological aspects, Heart attack -- Models, Biological sciences
Abstract

Left coronary ligation or a sham procedure were conducted on normal C57BL/6J mice. After six weeks, the mice underwent echocardiography and hemodynamic evaluation. Findings illustrated the applicability of ventricular remodeling in a mouse model of myocardial infarction and confirmed the possibility of quantifying indexes of modeling in vivo and postmortem. This model will be very useful for transgenic strains.

Published
1998

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