24 results on '"Depetris, Nadia"'
Search Results
2. Ventilation practices in burn patients—an international prospective observational cohort study
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Schultz, Marcus J, Horn, Janneke, Hollmann, Markus W, Preckel, Benedikt, Glas, Gerie J, Colpaert, Kirsten, Malbrain, Manu, Neto, Ary Serpa, Asehnoune, Karim, de Abreu, Marcello Gamma, Martin-Loeches, Ignacio, Pelosi, Paolo, Sjöberg, Folke, Binnekade, Jan M, Cleffken, Berry, Juffermans, Nicole P, Knape, Paul, Loef, Bert G, Mackie, David P, Enkhbaatar, Perenlei, Depetris, Nadia, Perner, Anders, Herrero, Eva, Cachafeiro, Lucia, Jeschke, Marc, Lipman, Jeffrey, Legrand, Matthieu, Horter, Johannes, Lavrentieva, Athina, Glas, Gerie, Kazemi, Alex, Guttormsen, Anne Berit, Huss, Frederik, Kol, Mark, Wong, Helen, Starr, Therese, De Crop, Luc, de Oliveira Filho, Wilson, Silva, João Manoel, Grion, Cintia MC, Jeschke, Marc G, Burnett, Marjorie, Mondrup, Frederik, Ravat, Francois, Fontaine, Mathieu, Asehoune, Karim, Le Floch, Renan, Jeanne, Mathieu, Bacus, Morgane, Chaussard, Maïté, Lehnhardt, Marcus, Mikhail, Bassem Daniel, Gille, Jochen, Sharkey, Aidan, Trommel, Nicole, Reidinga, Auke C, Vieleers, Nadine, Tilsley, Anna, Onarheim, Henning, Bouza, Maria Teresa, Agrifoglio, Alexander, Fredén, Filip, Palmieri, Tina, Painting, Lynda E, and investigators, LAMiNAR
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Paediatrics ,Biomedical and Clinical Sciences ,Physical Injury - Accidents and Adverse Effects ,Clinical Research ,Lung ,Respiratory ,Mechanical ventilation ,Inhalation trauma ,Lung-protective ,Critical care ,LAMiNAR investigators ,Clinical sciences ,Medical biotechnology ,Biomedical engineering - Abstract
BackgroundIt is unknown whether lung-protective ventilation is applied in burn patients and whether they benefit from it. This study aimed to determine ventilation practices in burn intensive care units (ICUs) and investigate the association between lung-protective ventilation and the number of ventilator-free days and alive at day 28 (VFD-28).MethodsThis is an international prospective observational cohort study including adult burn patients requiring mechanical ventilation. Low tidal volume (V T) was defined as V T ≤ 8 mL/kg predicted body weight (PBW). Levels of positive end-expiratory pressure (PEEP) and maximum airway pressures were collected. The association between V T and VFD-28 was analyzed using a competing risk model. Ventilation settings were presented for all patients, focusing on the first day of ventilation. We also compared ventilation settings between patients with and without inhalation trauma.ResultsA total of 160 patients from 28 ICUs in 16 countries were included. Low V T was used in 74% of patients, median V T size was 7.3 [interquartile range (IQR) 6.2-8.3] mL/kg PBW and did not differ between patients with and without inhalation trauma (p = 0.58). Median VFD-28 was 17 (IQR 0-26), without a difference between ventilation with low or high V T (p = 0.98). All patients were ventilated with PEEP levels ≥5 cmH2O; 80% of patients had maximum airway pressures
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- 2021
3. Quality indicators in burn care: An international burn care professionals survey to define them
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Dash, Suvashis, Pompermaier, Laura, Lavrentieva, Athina, Rogers, Alan David, and Depetris, Nadia
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- 2023
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4. Renal replacement therapy for acute kidney injury in burn patients, an international survey and a qualitative review of current controversies
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Lavrentieva, Athina, Depetris, Nadia, Moiemen, Naiem, Joannidis, Michael, and Palmieri, Tina Louise
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- 2022
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5. The 3rd Educational Course of the European Burns Association (EBA).
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Depetris, Nadia, de Jong, Alette E. E., Schiestl, Clemens, Siemers, Frank, Meirte, Jill, Vuola, Jyrki, Cabral, Luís, Van Zuijlen, Paul, and Almeland, Stian
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- 2024
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6. Burn center function during the COVID-19 pandemic: An international multi-center report of strategy and experience
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Barret, Juan P., Chong, Si Jack, Depetris, Nadia, Fisher, Mark D., Luo, Gaoxing, Moiemen, Naiem, Pham, Tam, Qiao, Liang, Wibbenmeyer, Lucy, and Matsumura, Hajime
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- 2020
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7. Coupled-plasma filtration and adsorption for severe burn patients with septic shock and acute kidney injury treated with renal replacement therapy
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Mariano, Filippo, Hollo’, Zsuzsanna, Depetris, Nadia, Malvasio, Valeria, Mella, Alberto, Bergamo, Daniela, Pensa, Anna, Berardino, Maurizio, Stella, Maurizio, and Biancone, Luigi
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- 2020
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8. Response to Letter to Editor regarding the manuscript 'Quality indicators in burn care: An international burn care professionals survey to define them'
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Depetris, Nadia, Lavrentieva, Athina, Dash, Suvashis, Rogers, Alan David, Pompermaier, Laura, Depetris, Nadia, Lavrentieva, Athina, Dash, Suvashis, Rogers, Alan David, and Pompermaier, Laura
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- 2024
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9. 20th Congress of the European Burns Association (EBA)
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Depetris, Nadia, primary, De Jong, Alette, additional, Schiestl, Clemens, additional, Duteille, Franck, additional, Meirte, Jill, additional, Barret-Nerin, Joan P., additional, Van Zuijlen, Paul, additional, Vuola, Jyrki, additional, and Almeland, Stian, additional
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- 2023
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10. Impact of COVID-19 on global burn care
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Rai Shankar Man, Keswani Sunil, Fisher Mark, Ntirenganya Faustin, Tanveer Ahmed, Vana Luiz Philipe Molina, Carter Jeffery, Junlin Liao, Depetris Nadia, Horwath Briana, Wall Shelley, Leon-Villapalos Jorge, Chong Si Jack, Al-Tarrah Khaled, Nakarmi Kiran, Qiao Liang, Chamania Shobha, Nawar Ahmed, Juan P. Barret, Miranda-Altamirano Rodolfo, Adorno José, Kiyozumi Tetsuro, Pompermaier Laura, Corlew Scott, Matsumura Hajime, Allorto Nikki, Elmasry Moustafa, Olekwu Anthony, Steinvall Ingrid, Luo Gaoxing, Haik Josef, Moiemen Naiem, Potokar Tom, Institut Català de la Salut, [Laura P] Department of Hand Surgery, Plastic Surgery and Burns, Linköping University, Linköping, Sweden. Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden. Department of Global Health and Social Medicine Program in Global Surgery and Social Change, Harvard Medical School, Boston, MA, USA. [José A] Burn Unit at Regional Hospital of North Wing, Brasília, Brazil. [Nikki A] Pietermaritzburg Burn Service, Nelson Mandela School of Medicine, University of KwaZulu Natal, South Africa. [Khaled A] Albabtain Center for Burns and Plastic Surgery, Alshuwaikh Specialist Health District, Alsabah Health Region, Kuwait. [Barret J] Servei de Cirurgia Plàstica i Cremats, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. [Jeffery C] Louisiana State University Health Sciences Center, New Orleans, LA, USA, and Vall d'Hebron Barcelona Hospital Campus
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Low income ,Telemedicine ,Coronavirus disease 2019 (COVID-19) ,Burn Units ,Health Services Administration::Patient Care Management::Delivery of Health Care::Telemedicine [HEALTH CARE] ,Nursing ,Critical Care and Intensive Care Medicine ,Logistic regression ,COVID-19 (Malaltia) ,Article ,administración de los servicios de salud::gestión de la atención al paciente::prestación sanitaria::telemedicina [ATENCIÓN DE SALUD] ,Surgical procedures ,Health care ,Pandemic ,virosis::infecciones por virus ARN::infecciones por Nidovirales::infecciones por Coronaviridae::infecciones por Coronavirus [ENFERMEDADES] ,Burn care ,Humans ,Standard of care ,Medicine ,Burn unit ,Resource allocation ,COVID-19 ,Location ,Pandemics ,instalaciones, servicios y personal de asistencia sanitaria::centros sanitarios::unidades hospitalarias::unidades de cuidados intensivos::unidades de quemados [ATENCIÓN DE SALUD] ,business.industry ,Omvårdnad ,Virus Diseases::RNA Virus Infections::Nidovirales Infections::Coronaviridae Infections::Coronavirus Infections [DISEASES] ,Telemedicina ,General Medicine ,medicine.disease ,Emergency Medicine ,Surgery ,Observational study ,Medical emergency ,Cremades ,Burns ,business ,Health Care Facilities, Manpower, and Services::Health Facilities::Hospital Units::Intensive Care Units::Burn Units [HEALTH CARE] ,Delivery of Health Care - Abstract
Background: Worldwide, different strategies have been chosen to face the COVID-19-patient surge, often affecting access to health care for other patients. This observational study aimed to investigate whether the standard of burn care changed globally during the pan-demic, and whether country acute accent s income, geographical location, COVID-19-transmission pat-tern, and levels of specialization of the burn units affected reallocation of resources and access to burn care.Methods: The Burn Care Survey is a questionnaire developed to collect information on the capacity to provide burn care by burn units around the world, before and during the pandemic. The survey was distributed between September and October 2020. McNemar`s test analyzed differences between services provided before and during the pandemic, chi 2 or Fishers exact test differences between groups. Multivariable logistic regression analyzed the independent effect of different factors on keeping the burn units open during the pandemic.Results: The survey was completed by 234 burn units in 43 countries. During the pandemic, presence of burn surgeons did not change (p = 0.06), while that of anesthetists and dedi-cated nursing staff was reduced (< 0.01), and so did the capacity to manage patients in all age groups (p = 0.04). Use of telemedicine was implemented (p < 0.01), collaboration be-tween burn centers was not. Burn units in LMICs and LICs were more likely to be closed, after adjustment for other factors.Conclusions: During the pandemic, most burn units were open, although availability of standard resources diminished worldwide. The use of telemedicine increased, suggesting the implementation of new strategies to manage burns. Low income was independently associated with reduced access to burn care.(c) 2021 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
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- 2022
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11. 19th European Burns Association Congress
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Depetris, Nadia, primary and Stella, Maurizio, additional
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- 2022
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12. A Randomized Trial of Enteral Glutamine for Treatment of Burn Injuries
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Heyland, Daren K., primary, Wibbenmeyer, Lucy, additional, Pollack, Jonathan A., additional, Friedman, Bruce, additional, Turgeon, Alexis F., additional, Eshraghi, Niknam, additional, Jeschke, Marc G., additional, Bélisle, Sylvain, additional, Grau, Daisy, additional, Mandell, Samuel, additional, Velamuri, Sai R., additional, Hundeshagen, Gabriel, additional, Moiemen, Naiem, additional, Shokrollahi, Kayvan, additional, Foster, Kevin, additional, Huss, Fredrik, additional, Collins, Declan, additional, Savetamal, Alisa, additional, Gurney, Jennifer M., additional, Depetris, Nadia, additional, Stoppe, Christian, additional, Ortiz-Reyes, Luis, additional, Garrel, Dominique, additional, and Day, Andrew G., additional
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- 2022
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13. Colistin Therapy, Survival and Renal Replacement Therapy in Burn Patients: A 10-Year Single-Center Cohort Study
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Mariano, Filippo, primary, Malvasio, Valeria, additional, Risso, Daniela, additional, Depetris, Nadia, additional, Pensa, Anna, additional, Fucale, Giacomo, additional, Gennari, Fabrizio, additional, Biancone, Luigi, additional, and Stella, Maurizio, additional
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- 2022
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14. A Randomized Trial of Enteral Glutamine for Treatment of Burn Injuries
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Heyland, Daren K., Wibbenmeyer, Lucy, Pollack, Jonathan A., Friedman, Bruce, Turgeon, Alexis F., Eshraghi, Niknam, Jeschke, Marc G., Bélisle, Sylvain, Grau, Daisy, Mandell, Samuel, Velamuri, Sai R., Hundeshagen, Gabriel, Moiemen, Naiem, Shokrollahi, Kayvan, Foster, Kevin, Huss, Fredrik, Collins, Declan, Savetamal, Alisa, Gurney, Jennifer M., Depetris, Nadia, Stoppe, Christian, Ortiz-Reyes, Luis, Garrel, Dominique, Day, Andrew G., Heyland, Daren K., Wibbenmeyer, Lucy, Pollack, Jonathan A., Friedman, Bruce, Turgeon, Alexis F., Eshraghi, Niknam, Jeschke, Marc G., Bélisle, Sylvain, Grau, Daisy, Mandell, Samuel, Velamuri, Sai R., Hundeshagen, Gabriel, Moiemen, Naiem, Shokrollahi, Kayvan, Foster, Kevin, Huss, Fredrik, Collins, Declan, Savetamal, Alisa, Gurney, Jennifer M., Depetris, Nadia, Stoppe, Christian, Ortiz-Reyes, Luis, Garrel, Dominique, and Day, Andrew G.
- Abstract
BACKGROUND Glutamine is thought to have beneficial effects on the metabolic and stress response to severe injury. Clinical trials involving patients with burns and other critically ill patients have shown conflicting results regarding the benefits and risks of glutamine supplementation. METHODS In a double-blind, randomized, placebo-controlled trial, we assigned patients with deep second-or third-degree burns (affecting >= 10% to >= 20% of total body-surface area, depending on age) within 72 hours after hospital admission to receive 0.5 g per kilogram of body weight per day of enterally delivered glutamine or placebo. Trial agents were given every 4 hours through a feeding tube or three or four times a day by mouth until 7 days after the last skin grafting procedure, discharge from the acute care unit, or 3 months after admission, whichever came first. The primary outcome was the time to discharge alive from the hospital, with data censored at 90 days. We calculated subdistribution hazard ratios for discharge alive, which took into account death as a competing risk. RESULTS A total of 1209 patients with severe burns (mean burn size, 33% of total body-surface area) underwent randomization, and 1200 were included in the analysis (596 patients in the glutamine group and 604 in the placebo group). The median time to discharge alive from the hospital was 40 days (interquartile range, 24 to 87) in the glutamine group and 38 days (interquartile range, 22 to 75) in the placebo group (subdistribution hazard ratio for discharge alive, 0.91; 95% confidence interval [CI], 0.80 to 1.04; P = 0.17). Mortality at 6 months was 17.2% in the glutamine group and 16.2% in the placebo group (hazard ratio for death, 1.06; 95% CI, 0.80 to 1.41). No substantial between-group differences in serious adverse events were observed. CONCLUSIONS In patients with severe burns, supplemental glutamine did not reduce the time to discharge alive from the hospital.
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- 2022
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15. Colistin Therapy, Survival and Renal Replacement Therapy in Burn Patients: A 10-Year Single-Center Cohort Study
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Mariano,Filippo, Malvasio,Valeria, Risso,Daniela, Depetris,Nadia, Pensa,Anna, Fucale,Giacomo, Gennari,Fabrizio, Biancone,Luigi, Stella,Maurizio, Mariano,Filippo, Malvasio,Valeria, Risso,Daniela, Depetris,Nadia, Pensa,Anna, Fucale,Giacomo, Gennari,Fabrizio, Biancone,Luigi, and Stella,Maurizio
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Filippo Mariano,1,2,* Valeria Malvasio,3,4,* Daniela Risso,3 Nadia Depetris,5 Anna Pensa,3,6 Giacomo Fucale,7 Fabrizio Gennari,4 Luigi Biancone,1,2 Maurizio Stella3 1Nephrology, Dialysis and Transplantation U, Department of General and Specialized Medicine, City of Science and Health, CTO Hospital, Torino, Italy; 2Department of Medical Sciences, University of Torino, Torino, Italy; 3Burn Center and Plastic Surgery, Department of General and Specialized Surgery, City of Science and Health, CTO Hospital, Torino, Italy; 4Department of Pediatric General Surgery, City of Science and Health, Regina Margherita Childrenâs Hospital, Torino, Italy; 5Anesthesia and Intensive Care 3, Department of Anesthesia and Intensive Care, City of Science and Health, CTO Hospital, Torino, Italy; 6Department of Surgical Sciences, University of Torino, Torino, Italy; 7Laboratory of Microbiology and Virology, City of Science and Health, Molinette Hospital, Torino, Italy*These authors contributed equally to this workCorrespondence: Filippo Mariano, Nephrology, Dialysis and Transplantation U, AOU City of Science and Health, CTO Hospital, Via G. Zuretti 29, Torino, 10126, Italy, Tel +39-011-6933-674, Fax +39-011-6933-672, Email filippo.mariano@unito.itPurpose: Colistin is still a therapeutic cornerstone against multidrug-resistant gram-negative bacteria (MDRGN), mostly when other antibiotics do not gain adequate activity on these strains. In the present study, we evaluated in a cohort of burn patients the relationship between colistin therapy, survival and requirement of renal replacement therapy (CRRT).Patients and Methods: Retrospective study of 133 burn patients treated with iv colistimethate sodium (loading dose 9.0 Ã 106 IU, maintenance dose 4.5 Ã 106 IU BID) and 35 treated with other antibiotics for MDRGN infection including Acinetobacter baumannii, Pseudomonas aeruginosa, and Klebsiella pneumoniae between January 2008 and December 2017. Multivariate analysis wi
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- 2022
16. European Burns Association (EBA)—Summer 2024 News.
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Almeland, Stian and Depetris, Nadia
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- 2024
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17. Ventilation practices in burn patients-an international prospective observational cohort study
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Glas, Gerie J., Horn, Janneke, Hollmann, Markus W., Preckel, Benedikt, Colpaert, Kirsten, Malbrain, Manu, Neto, Ary Serpa, Asehnoune, Karim, de Abreu, Marcello Gamma, Martin-Loeches, Ignacio, Pelosi, Paolo, Sjoberg, Folke, Binnekade, Jan M., Cleffken, Berry, Juffermans, Nicole P., Knape, Paul, Loef, Bert G., Mackie, David P., Enkhbaatar, Perenlei, Depetris, Nadia, Perner, Anders, Herrero, Eva, Cachafeiro, Lucia, Jeschke, Marc, Lipman, Jeffrey, Legrand, Matthieu, Horter, Johannes, Lavrentieva, Athina, Kazemi, Alex, Guttormsen, Anne Berit, Huss, Fredrik, Kol, Mark, Wong, Helen, Starr, Therese, De Crop, Luc, de Oliveira Filho, Wilson, Silva Junior, Joao Manoel, Grion, Cintia M. C., Burnett, Marjorie, Mondrup, Frederik, Ravat, Francois, Fontaine, Mathieu, Le Floch, Renan, Jeanne, Mathieu, Bacus, Morgane, Chaussard, Maite, Lehnhardt, Marcus, Mikhail, Bassem Daniel, Gille, Jochen, Sharkey, Aidan, Trommel, Nicole, Reidinga, Auke C., Vieleers, Nadine, Tilsley, Anna, Onarheim, Henning, Teresa Bouza, Maria, Agrifoglio, Alexander, Freden, Filip, Palmieri, Tina, Painting, Lynda E., and Schultz, Marcus J.
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Critical care ,Mechanical ventilation ,Anestesi och intensivvård ,Anesthesiology and Intensive Care ,Lung-protective ,Inhalation trauma - Abstract
Background: It is unknown whether lung-protective ventilation is applied in burn patients and whether they benefit from it. This study aimed to determine ventilation practices in burn intensive care units (ICUs) and investigate the association between lung-protective ventilation and the number of ventilator-free days and alive at day 28 (VFD-28). Methods: This is an international prospective observational cohort study including adult burn patients requiring mechanical ventilation. Low tidal volume (V-T) was defined as V-T = 5 cmH(2)O; 80% of patients had maximum airway pressures Funding Agencies|Nederlandse Brandwonden Stichting (the Dutch Burn Association, Beverwijk, The Netherlands)Netherlands Government
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- 2021
18. Ventilation practices in burn patients : an international prospective observational cohort study
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Glas, Gerie J, Horn, Janneke, Hollmann, Markus W, Preckel, Benedikt, Colpaert, Kirsten, Malbrain, Manu, Neto, Ary Serpa, Asehnoune, Karim, de Abreu, Marcello Gamma, Martin-Loeches, Ignacio, Pelosi, Paolo, Sjöberg, Folke, Binnekade, Jan M, Cleffken, Berry, Juffermans, Nicole P, Knape, Paul, Loef, Bert G, Mackie, David P, Enkhbaatar, Perenlei, Depetris, Nadia, Perner, Anders, Herrero, Eva, Cachafeiro, Lucia, Jeschke, Marc, Lipman, Jeffrey, Legrand, Matthieu, Horter, Johannes, Lavrentieva, Athina, Kazemi, Alex, Guttormsen, Anne Berit, Huss, Frederik, Kol, Mark, Wong, Helen, Starr, Therese, De Crop, Luc, de Oliveira Filho, Wilson, Manoel Silva Junior, João, Grion, Cintia M C, Burnett, Marjorie, Mondrup, Frederik, Ravat, Francois, Fontaine, Mathieu, Floch, Renan Le, Jeanne, Mathieu, Bacus, Morgane, Chaussard, Maïté, Lehnhardt, Marcus, Mikhail, Bassem Daniel, Gille, Jochen, Sharkey, Aidan, Trommel, Nicole, Reidinga, Auke C, Vieleers, Nadine, Tilsley, Anna, Onarheim, Henning, Bouza, Maria Teresa, Agrifoglio, Alexander, Fredén, Filip, Palmieri, Tina, Painting, Lynda E, Schultz, Marcus J, and LAMiNAR investigators, [missing]
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OUTCOMES ,MORTALITY ,CONSERVATIVE OXYGEN-THERAPY ,Biomedical Engineering ,RESPIRATORY-DISTRESS-SYNDROME ,Dermatology ,ASSOCIATION ,Critical Care and Intensive Care Medicine ,INTENSIVE-CARE UNITS ,PROTECTIVE VENTILATION ,PREVENTION ,MECHANICAL VENTILATION ,Critical care ,INHALATION INJURY ,Lung-protective ,Medicine and Health Sciences ,Emergency Medicine ,Immunology and Allergy ,Surgery ,Inhalation trauma - Abstract
Background: It is unknown whether lung-protective ventilation is applied in burn patients and whether they benefit from it. This study aimed to determine ventilation practices in burn intensive care units (ICUs) and investigate the association between lung-protective ventilation and the number of ventilator-free days and alive at day 28 (VFD-28). Methods: This is an international prospective observational cohort study including adult burn patients requiring mechanical ventilation. Low tidal volume (V-T) was defined as V-T = 5 cmH(2)O; 80% of patients had maximum airway pressures
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- 2021
19. Postprandial triglyceride-rich lipoprotein metabolism and insulin sensitivity in nonalcoholic steatohepatitis patients
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Cassader, Maurizio, Gambino, Roberto, Musso, Giovanni, Depetris, Nadia, Mecca, Fabio, Cavallo-Perin, Paolo, Pacini, Giovanni, Rizzetto, Mario, and Pagano, Gianfranco
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- 2001
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20. Nonalcoholic steatohepatitis, insulin resistance, and metabolic syndrome: Further evidence for an etiologic association
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Pagano, Gianfranco, Pacini, Giovanni, Musso, Giovanni, Gambino, Roberto, Mecca, Fabio, Depetris, Nadia, Cassader, Maurizio, David, Ezio, Cavallo-Perin, Paolo, and Rizzetto, Mario
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- 2002
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21. Analgesia, Sedation and Delirium Management in Adult Critically Ill Burns : a Survey
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Depetris, Nadia
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Analgesia, sedation and delirium management in adult critically ill burns: a surveyObjectivesThis study aims to assess the current practices of analgesia, sedation and delirium monitoring and treatment strategies in burn ICUs.MethodsWe designed a web survey consisting of four parts: physician and institutional demographics, management of pain, sedation and delirium in burn patients. The questionnaire was distributed by email to 230 burn specialists worldwide.ResultsPhysician and Institutional demographics.A total of 40 respondents worldwide submitted valuable data in the 2 months period, equivalent to a response rate of 16%.Of all respondents, 20 (50%) were from Europe, 7 (17.5%) from North America, 6 (15%) from Africa and 12 (30%) from other regions (including Western Pacific, Southeast Asia, Central and South Americas and Eastern Mediterranean). 20 (50%) respondents were intensivists/anaesthesists, 18 (45%) surgeons and 2 (5%) other professionals.Analgesia.The vast majority (92.5%) reported they routinely screen severe burns for pain, but 27.5% declared no specific score is used. The most popular analgesics were opioids, specifically morphine (75%) and fentanyl (72.5%). Among non-pharmacological approaches, the most used were psychological support (62.5%). Only a minority of respondents apply hypnosis (12.5%).Sedation.A significant percentage (70%) affirmed they routinely screen their patients for sedation, but 30% do not use a specific scale. The sedatives used more often were midazolam (72.5%) and propofol (55%). 20% of specialists affirmed to use dexmedetomidine frequently in their routine practice.Delirium.The majority (70%) affirmed to routinely assess burn patients for delirium, but 57.5% do not use a specific score. Burn specialists affirmed to prevent delirium in their patients combining pharmacological and non-pharmacological approaches (62.5%).ConclusionsAwareness concerning pain, sedation and delirium is increasing among burn specialists. Efforts are still needed to implement guidelines and best practices.
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- 2017
22. Implementation of a pain protocol including hypnosis in a burn centre: the training program
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Depetris, Nadia, primary
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- 2017
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23. Analgesia, sedation and delirium management in adult critically ill burns: a survey
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Depetris, Nadia, primary
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- 2017
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24. Ventilation practices in burn patients-an international prospective observational cohort study.
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Schultz MJ, Horn J, Hollmann MW, Preckel B, Glas GJ, Colpaert K, Malbrain M, Neto AS, Asehnoune K, de Abreu MG, Martin-Loeches I, Pelosi P, Sjöberg F, Binnekade JM, Cleffken B, Juffermans NP, Knape P, Loef BG, Mackie DP, Enkhbaatar P, Depetris N, Perner A, Herrero E, Cachafeiro L, Jeschke M, Lipman J, Legrand M, Horter J, Lavrentieva A, Glas G, Kazemi A, Guttormsen AB, Huss F, Kol M, Wong H, Starr T, De Crop L, de Oliveira Filho W, Manoel Silva Junior J, Grion CMC, Jeschke MG, Burnett M, Mondrup F, Ravat F, Fontaine M, Asehoune K, Floch RL, Jeanne M, Bacus M, Chaussard M, Lehnhardt M, Mikhail BD, Gille J, Sharkey A, Trommel N, Reidinga AC, Vieleers N, Tilsley A, Onarheim H, Bouza MT, Agrifoglio A, Fredén F, Palmieri T, and Painting LE
- Abstract
Background: It is unknown whether lung-protective ventilation is applied in burn patients and whether they benefit from it. This study aimed to determine ventilation practices in burn intensive care units (ICUs) and investigate the association between lung-protective ventilation and the number of ventilator-free days and alive at day 28 (VFD-28)., Methods: This is an international prospective observational cohort study including adult burn patients requiring mechanical ventilation. Low tidal volume ( V
T ) was defined as VT ≤ 8 mL/kg predicted body weight (PBW). Levels of positive end-expiratory pressure (PEEP) and maximum airway pressures were collected. The association between VT and VFD-28 was analyzed using a competing risk model. Ventilation settings were presented for all patients, focusing on the first day of ventilation. We also compared ventilation settings between patients with and without inhalation trauma., Results: A total of 160 patients from 28 ICUs in 16 countries were included. Low VT was used in 74% of patients, median VT size was 7.3 [interquartile range (IQR) 6.2-8.3] mL/kg PBW and did not differ between patients with and without inhalation trauma ( p = 0.58). Median VFD-28 was 17 (IQR 0-26), without a difference between ventilation with low or high VT ( p = 0.98). All patients were ventilated with PEEP levels ≥5 cmH2 O; 80% of patients had maximum airway pressures <30 cmH2 O., Conclusion: In this international cohort study we found that lung-protective ventilation is used in the majority of burn patients, irrespective of the presence of inhalation trauma. Use of low VT was not associated with a reduction in VFD-28., Trial Registration: Clinicaltrials.gov NCT02312869. Date of registration: 9 December 2014., (© The Author(s) 2021. Published by Oxford University Press.)- Published
- 2021
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