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1. P932: ON-DEMAND PLERIXAFOR WITH CYCLOPHOSPHAMIDE AND G-CSF FOR HEMATOPOIETIC STEM-CELL MOBILIZATION IN MULTIPLE MYELOMA PATIENTS: FINAL RESULTS OF THE MOZOBL06877 STUDY

Author

Mina, R., primary, Bonello, F., additional, Fazio, F., additional, Saccardi, R., additional, Bongarzoni, V., additional, Marchesi, F., additional, Bertuglia, G., additional, Curci, P., additional, Lemoli, R. M., additional, Ballanti, S., additional, Dentamaro, T., additional, Benevolo, G., additional, Capra, A., additional, Floris, R., additional, Tosi, P., additional, Olivieri, A., additional, Rota-Scalabrini, D., additional, Cangialosi, C., additional, Cavo, M., additional, Corradini, P., additional, Milone, G., additional, Boccadoro, M., additional, and Larocca, A., additional

Published
2022
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4. High incidence of post-transplant cytomegalovirus reactivations in myeloma patients undergoing autologous stem cell transplantation after treatment with bortezomib-based regimens: a survey from the Rome Transplant Network

Author

Marchesi, F., Mengarelli, A., Giannotti, F., Tendas, A., Anaclerico, B., Porrini, R., Picardi, A., Cerchiara, E., Dentamaro, T., Chierichini, A., Romeo, A., Cudillo, L., Montefusco, E., Tirindelli, M. C., De Fabritiis, P., Annino, L., Petti, M. C., Monarca, B., Arcese, W., and Avvisati, G.

Published
2014
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6. Hematopoietic stem cell transplantation for multiple sclerosis: A retrospective multicenter study

Author

Fassas, A.S., Passweg, J. R., Anagnostopoulos, A., Kazis, A., Kozak, T., Havrdova, E., Carreras, E., Graus, F., Kashyap, A., Openshaw, H., Schipperus, M., Deconinck, E., Mancardi, G., Marmont, A., Hansz, J., Rabusin, M., Zuazu Nagore, F. J., Besalduch, J., Dentamaro, T., Fouillard, L., Hertenstein, B., La Nasa, G., Musso, M., Papineschi, F., Rowe, J. M., Saccardi, R., Steck, A., Kappos, L., Gratwohl, A., Tyndall, A., and for the Autoimmune Disease Working Party of the EBMT (European Group for Blood and Marrow Transplantation)

Published
2002
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8. Disability among recipients of autologous or allogeneic haematopoietic stem cell transplant: a retrospective study from the Quality of Life Working Party of the Rome Tranplant Network: P1421

Author

Ciscato, C., Tendas, A., Dʼapolito, A., Mauroni, M. R., Pilozzi, V., Cacciaraichi, S., Viggiani, C., Mazza, P., Molinari, V., Purificato, K., Grigore, D., Rana, I., Mengarelli, A., Pignatelli, A., Cupelli, L., Anaclerico, B., Porrini, R., Annibali, O., Mirabile, M., Palumbo, G., Trenta, F., Tirindelli, M. C., Dentamaro, T., De fabritiis, P., and Arcese, W.

Published
2011

10. Rome Transplant Network, a metropolitan haematopoietic stem cell transplant programme: P824

Author

Arcese, W, Picardi, A., Mauroni, M. R., Adorno, G., Lanti, A., Locatelli, F., Caniglia, M., Ciscato, C., Isacchi, G., Zinno, F., De Fabritiis, P., Dentamaro, T., Delogu, S., Avvisati, G., Tirindelli, M. C., Mazzaroni, M., Petti, C., Mengarelli, A., Pignatelli, A., Monarca, B., Montefusco, E., Grigora, D., Annino, L., Chierichini, A., Pilozzi, V., Angelini, S., Mangione, I., Papa, C., and Miccichè, S.

Published
2011

19. Incidence, Risk Factors and Outcome of Pre-engraftment Gram-Negative Bacteremia After Allogeneic and Autologous Hematopoietic Stem Cell Transplantation: An Italian Prospective Multicenter Survey

Author

Girmenia, C, Bertaina, A, Piciocchi, A, Perruccio, K, Algarotti, A, Busca, A, Cattaneo, C, Raiola, Am, Guidi, S, Iori, Ap, Candoni, A, Irrera, G, Milone, G, Marcacci, G, Scimè, R, Musso, M, Cudillo, L, Sica, S, Castagna, L, Corradini, P, Marchesi, F, Pastore, D, Alessandrino, Ep, Annaloro, C, Ciceri, F, Santarone, S, Nassi, L, Farina, C, Viscoli, C, Rossolini, Gm, Bonifazi, F, Rambaldi, A, Capria, S, Mastronuzzi, A, Pagliara, D, Bernaschi, P, Amico, L, Carotti, A, Mencacci, A, Bruno, B, Costa, C, Passi, A, Ravizzola, G, Angelucci, E, Marchese, A, Pecile, P, Ventura, G, Fanin, R, Scarparo, C, Barbaro, A, Leotta, S, Marchese, Ae, Becchimanzi, C, Donnarumma, D, Tringali, S, Baldi, Mt, Scalone, R, Picardi, A, Arcese, W, Fontana, C, Giammarco, S, Spanu, T, Crocchiolo, R, Casari, E, Mussetti, A, Conte, E, Ensoli, F, Miragliotta, G, Marone, P, Arghittu, M, Greco, R, Forcina, A, Chichero, P, Di Bartolomeo, P, Fazii, P, Kroumova, V, Decembrino, N, Zecca, M, Pisapia, G, Palazzo, G, Lanino, E, Faraci, M, Castagnola, E, Bandettini, R, Pastano, R, Sammassimo, S, Passerini, R, Stefani, Pm, Gherlinzoni, F, Rigoli, R, Prezioso, L, Cambò, B, Calderaro, A, Carella, Am, Cascavilla, N, Labonia, Mt, Celeghini, I, Mordini, N, Piana, F, Vacca, A, Sanna, M, Podda, G, Corsetti, Mt, Rocchetti, A, Cilloni, D, De Gobbi, M, Bianco, O, Fagioli, F, Carraro, F, De Intinis, G, Severino, A, Proia, A, Parisi, G, Vallisa, D, Confalonieri, M, Russo, D, Malagola, M, Galieni, P, Falcioni, S, Travaglini, V, Raimondi, R, Borghero, C, Pavan, G, Prete, A, Belotti, T, Ambretti, S, Imola, M, Mianulli, Am, Pedna, Mf, Cesaro, S, Lo Cascio, G, Ferrari, A, Piedimonte, M, Santino, I, Calandrelli, M, Olivieri, A, Orecchioni, F, Mirabile, M, Centurioni, R, Gironacci, L, Caravelli, D, Gallo, S, De Filippi, M, Cupelli, L, Dentamaro, T, Falco, S, Eugenio, Os, Marotta, S, Risitano, A, Lula, D, Musto, P, Pietrantuono, G, Traficante, A, Cerchiara, E, Tirindelli, Mc, Dicuonzo, G, Chierichini, A, Anaclerico, B, and Placanica, P.

Published
2017

20. Homecare-based motor rehabilitation in musculoskeletal chronic graft versus host disease

Author

Tendas, A., Boschetto, C., Baraldi, L., Caiazza, E., Cupelli, L., Lentini, R., Trawinska, M., Palombi, M., Ales, M., Morino, L., Giovannini, M., Scaramucci, L., Cartoni, C., Dentamaro, T., Arcese, W., De Fabritiis, P., Niscola, P., and Mandelli, F.

Subjects
Palliative treatment -- Methods, Graft versus host reaction -- Development and progression -- Care and treatment -- Patient outcomes, Stem cells -- Transplantation, Medicine, Physical -- Usage -- Patient outcomes, Health
Abstract

Byline: A. Tendas, C. Boschetto, L. Baraldi, E. Caiazza, L. Cupelli, R. Lentini, M. Trawinska, M. Palombi, M. Ales, L. Morino, M. Giovannini, L. Scaramucci, C. Cartoni, T. Dentamaro, W. [...]

Published
2011

21. Incidence, Risk Factors and Outcome of Pre-engraftment Gram-Negative Bacteremia after Allogeneic and Autologous Hematopoietic Stem Cell Transplantation: An Italian Prospective Multicenter Survey

Author

Girmenia, C., Bertaina, A., Piciocchi, A., Perruccio, K., Algarotti, A., Busca, A., Cattaneo, C., Raiola, A. M., Guidi, S., Iori, A. P., Candoni, A., Irrera, G., Milone, G., Marcacci, G., Scime, R., Musso, M., Cudillo, L., Sica, Simona, Castagna, Luigi, Corradini, P., Marchesi, F., Pastore, D., Alessandrino, E. P., Annaloro, C., Ciceri, F., Santarone, S., Nassi, L., Farina, C., Viscoli, C., Rossolini, G. M., Bonifazi, F., Rambaldi, A., Capria, S., Mastronuzzi, A., Pagliara, D., Bernaschi, P., Amico, L., Carotti, A., Mencacci, A., Bruno, Brunella, Costa, C., Passi, A., Ravizzola, G., Angelucci, E., Marchese, Alessandra Maria, Pecile, P., Ventura, Giulio, Fanin, R., Scarparo, C., Barbaro, A., Leotta, Salvatore Nuccio, Marchese, A. E., Becchimanzi, C., Donnarumma, D., Tringali, S., Baldi, M. T., Scalone, R., Picardi, A., Arcese, W., Fontana, Cecilia Alejandra, Giammarco, S., Spanu, Teresa, Crocchiolo, R., Casari, E., Mussetti, A., Conte, Eliana, Ensoli, F., Miragliotta, G., Marone, P., Arghittu, M., Greco, R., Forcina, A., Chichero, P., Di Bartolomeo, P., Fazii, P., Kroumova, V., Decembrino, N., Zecca, M., Pisapia, Giovanni, Palazzo, G., Lanino, E., Faraci, M., Castagnola, E., Bandettini, R., Pastano, R., Sammassimo, S., Passerini, R., Stefani, P. M., Gherlinzoni, F., Rigoli, R., Prezioso, L., Cambo, B., Calderaro, A., Carella, A. M., Cascavilla, N., Labonia, M. T., Celeghini, I., Mordini, N., Piana, F., Vacca, A., Sanna, Maria Maddalena, Podda, G., Corsetti, M. T., Rocchetti, A., Cilloni, D., De Gobbi, M., Bianco, O., Fagioli, F., Carraro, F., De Intinis, G., Severino, A., Proia, Anna Silvia, Parisi, G., Vallisa, D., Confalonieri, Marco, Russo, D., Malagola, M., Galieni, P., Falcioni, S., Travaglini, V., Raimondi, Maria Rosa, Borghero, C., Pavan, Giuseppe, Prete, A., Belotti, T., Ambretti, S., Imola, M., Mianulli, A. M., Pedna, M. F., Cesaro, S., Lo Cascio, G., Ferrari, A., Piedimonte, M., Santino, I., Calandrelli, M., Olivieri, Alessandra, Orecchioni, F., Mirabile, M., Centurioni, R., Gironacci, L., Caravelli, D., Gallo, S., De Filippi, M., Cupelli, L., Dentamaro, T., Falco, S., Eugenio, O. S., Marotta, S., Risitano, A., Lula, D., Musto, P., Pietrantuono, G., Traficante, A., Cerchiara, E., Tirindelli, M. C., Dicuonzo, G., Chierichini, A., Anaclerico, B., Placanica, P., Sica S. (ORCID:0000-0003-2426-3465), Castagna L., Bruno B., Marchese A., Ventura G. (ORCID:0000-0002-0304-7264), Leotta S., Fontana C., Spanu T. (ORCID:0000-0003-1864-5184), Conte E., Pisapia G., Sanna M., Proia A., Confalonieri M. (ORCID:0000-0002-3708-379X), Raimondi R., Pavan G., Olivieri A., Girmenia, C., Bertaina, A., Piciocchi, A., Perruccio, K., Algarotti, A., Busca, A., Cattaneo, C., Raiola, A. M., Guidi, S., Iori, A. P., Candoni, A., Irrera, G., Milone, G., Marcacci, G., Scime, R., Musso, M., Cudillo, L., Sica, Simona, Castagna, Luigi, Corradini, P., Marchesi, F., Pastore, D., Alessandrino, E. P., Annaloro, C., Ciceri, F., Santarone, S., Nassi, L., Farina, C., Viscoli, C., Rossolini, G. M., Bonifazi, F., Rambaldi, A., Capria, S., Mastronuzzi, A., Pagliara, D., Bernaschi, P., Amico, L., Carotti, A., Mencacci, A., Bruno, Brunella, Costa, C., Passi, A., Ravizzola, G., Angelucci, E., Marchese, Alessandra Maria, Pecile, P., Ventura, Giulio, Fanin, R., Scarparo, C., Barbaro, A., Leotta, Salvatore Nuccio, Marchese, A. E., Becchimanzi, C., Donnarumma, D., Tringali, S., Baldi, M. T., Scalone, R., Picardi, A., Arcese, W., Fontana, Cecilia Alejandra, Giammarco, S., Spanu, Teresa, Crocchiolo, R., Casari, E., Mussetti, A., Conte, Eliana, Ensoli, F., Miragliotta, G., Marone, P., Arghittu, M., Greco, R., Forcina, A., Chichero, P., Di Bartolomeo, P., Fazii, P., Kroumova, V., Decembrino, N., Zecca, M., Pisapia, Giovanni, Palazzo, G., Lanino, E., Faraci, M., Castagnola, E., Bandettini, R., Pastano, R., Sammassimo, S., Passerini, R., Stefani, P. M., Gherlinzoni, F., Rigoli, R., Prezioso, L., Cambo, B., Calderaro, A., Carella, A. M., Cascavilla, N., Labonia, M. T., Celeghini, I., Mordini, N., Piana, F., Vacca, A., Sanna, Maria Maddalena, Podda, G., Corsetti, M. T., Rocchetti, A., Cilloni, D., De Gobbi, M., Bianco, O., Fagioli, F., Carraro, F., De Intinis, G., Severino, A., Proia, Anna Silvia, Parisi, G., Vallisa, D., Confalonieri, Marco, Russo, D., Malagola, M., Galieni, P., Falcioni, S., Travaglini, V., Raimondi, Maria Rosa, Borghero, C., Pavan, Giuseppe, Prete, A., Belotti, T., Ambretti, S., Imola, M., Mianulli, A. M., Pedna, M. F., Cesaro, S., Lo Cascio, G., Ferrari, A., Piedimonte, M., Santino, I., Calandrelli, M., Olivieri, Alessandra, Orecchioni, F., Mirabile, M., Centurioni, R., Gironacci, L., Caravelli, D., Gallo, S., De Filippi, M., Cupelli, L., Dentamaro, T., Falco, S., Eugenio, O. S., Marotta, S., Risitano, A., Lula, D., Musto, P., Pietrantuono, G., Traficante, A., Cerchiara, E., Tirindelli, M. C., Dicuonzo, G., Chierichini, A., Anaclerico, B., Placanica, P., Sica S. (ORCID:0000-0003-2426-3465), Castagna L., Bruno B., Marchese A., Ventura G. (ORCID:0000-0002-0304-7264), Leotta S., Fontana C., Spanu T. (ORCID:0000-0003-1864-5184), Conte E., Pisapia G., Sanna M., Proia A., Confalonieri M. (ORCID:0000-0002-3708-379X), Raimondi R., Pavan G., and Olivieri A.

Abstract

Background Gram-negative bacteremia (GNB) is a major cause of illness and death after hematopoietic stem cell transplantation (HSCT), and updated epidemiological investigation is advisable. Methods We prospectively evaluated the epidemiology of pre-engraftment GNB in 1118 allogeneic HSCTs (allo-HSCTs) and 1625 autologous HSCTs (auto-HSCTs) among 54 transplant centers during 2014 (SIGNB-GITMO-AMCLI study). Using logistic regression methods. we identified risk factors for GNB and evaluated the impact of GNB on the 4-month overall-survival after transplant. Results The cumulative incidence of pre-engraftment GNB was 17.3% in allo-HSCT and 9% in auto-HSCT. Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa were the most common isolates. By multivariate analysis, variables associated with GNB were a diagnosis of acute leukemia, a transplant from a HLA-mismatched donor and from cord blood, older age, and duration of severe neutropenia in allo-HSCT, and a diagnosis of lymphoma, older age, and no antibacterial prophylaxis in auto-HSCT. A pretransplant infection by a resistant pathogen was significantly associated with an increased risk of posttransplant infection by the same microorganism in allo-HSCT. Colonization by resistant gram-negative bacteria was significantly associated with an increased rate of infection by the same pathogen in both transplant procedures. GNB was independently associated with increased mortality at 4 months both in allo-HSCT (hazard ratio, 2.13; 95% confidence interval, 1.45-3.13; P <.001) and auto-HSCT (2.43; 1.22-4.84; P =.01). Conclusions Pre-engraftment GNB is an independent factor associated with increased mortality rate at 4 months after auto-HSCT and allo-HSCT. Previous infectious history and colonization monitoring represent major indicators of GNB. Clinical Trials registration NCT02088840.

Published
2017

23. Infections by carbapenem-resistant Klebsiella pneumoniae in SCT recipients: a nationwide retrospective survey from Italy

Author

Girmenia, C, Rossolini, Gm, Piciocchi, A, Bertaina, A, Pisapia, G, Pastore, D, Sica, S, Severino, A, Cudillo, L, Ciceri, F, Scimè, R, Lombardini, L, Viscoli, C, Rambaldi, A, the Gruppo Italiano Trapianto Midollo Osseo (GITMO), Frigeni, M, Corti, C, Mometto, G, Annaloro, C, Casari, E, Castagna, L, Rossi, G, Cattaneo, C, Russo, D, Cancelli, V, Alessandrino, Ep, Ripamonti, F, Pavan, F, Rovelli, A, Pecoraro, C, Busca, A, Carraro, F, Fagioli, F, Gallo, S, Caravelli, D, De Gobbi, M, Saglio, G, Castellino, C, Mordini, N, Gaidano, G, Nassi, L, Raimondi, R, Vespignani, M, Scattolin, Am, Panizzolo, Is, Cesaro, S, Candoni, A, Patriarca, F, Bacigalupo, A, Raiola, A, Castagnola, E, Lanino, E, Stanzani, M, Bandini, G, Massaccesi, E, Prete, A, Bassi, S, Vallisa, D, Caramatti, C, Aversa, F, Zuffa, E, Guidi, S, Bosi, A, Tintori, V, Iori, Ap, Capria, S, Arcese, W, Dentamaro, T, Fabritiis, Pd, Anaclerico, B, Chierichini, A, Piedimonte, M, Ferrari, A, Marchesi, F, Mengarelli, A, Cerchiara, E, Tirindelli, Mc, Gaziev, J, Majolino, I, Chiusolo, P, Lucarelli, B, Massei, Ms, Carotti, A, Perruccio, K, Caniglia, M, Santarone, S, Bartolomeo, Pd, Mazzotta, S, Galieni, P, Olivieri, A, Rosa, Gd, Risitano, A, Delia, M, Specchia, G, Palazzo, G, Messina, G, Irrera, G, Angelucci, E, Baronciani, D, Vacca, A, Crescimanno, A, Musso, M, Imbriani, A, Milone, G., Girmenia, C, Rossolini, Gm, Piciocchi, A, Bertaina, A, Pisapia, G, Pastore, D, Sica, S, Severino, A, Cudillo, L, Ciceri, Fabio, Scime, R, Lombardini, L, Viscoli, C, Rambaldi, A, and and the Gruppo Italiano Trapianto Midollo Osseo, (GITMO)

Subjects
Male, Klebsiella pneumoniae, Carbapenem resistant Klebsiella pneumoniae, Drug Resistance, carbapenem-resistant Klebsiella pneumoniae, colonization, sepsis, Allogeneic Hematopoietic Stem Cell Transplantation, Hematologic Diseases, hemic and lymphatic diseases, polycyclic compounds, Medicine, Adolescent, Adult, Aged, Allografts, Autografts, Female, Humans, Italy, Klebsiella Infections, Middle Aged, Retrospective Studies, Carbapenems, Drug Resistance, Bacterial, Stem Cell Transplantation, Hematology, Transplantation, biology, Bacterial, humanities, surgical procedures, operative, medicine.medical_specialty, Retrospective survey, Internal medicine, business.industry, Retrospective cohort study, Klebsiella infections, biology.organism_classification, Settore MED/15, infection, body regions, Settore MED/15 - MALATTIE DEL SANGUE, Immunology, business
Abstract

Infections by carbapenem-resistant Klebsiella pneumoniae (CRKp) represent a challenging problem after SCT. A retrospective survey (January 2010 to July 2013) involving 52 Italian centers was performed to assess the epidemiology and the prognostic factors of CRKp infections in auto- and allo-SCT. Cases of CRKp infection were reported in 53.4% of centers. CRKp infections were documented in 25 auto-SCTs and 87 allo-SCTs, with an incidence of 0.4% (from 0.1% in 2010 to 0.7% in 2013) and 2% (from 0.4% in 2010 to 2.9% in 2013), respectively. A CRKp colonization documented before or after transplant was followed by an infection in 25.8% of auto-SCT and 39.2% of allo-SCT patients. The infection-related mortality rates were 16% and 64.4%, respectively. A pre-transplant CRKp infection (hazard ratio (HR) 0.33, 95% confidence intervals (CIs) 0.15-0.74; P = 0.007) and a not CRKp-targeted first-line treatment (HR 2.67, 95% CI 1.43-4.99; P = 0.002) were independent factors associated with an increased mortality in allo-SCT patients who developed a CRKp infection. Our study shows challenging findings of CRKp infections in SCT patients in Italy particularly after allo-SCT. The detection of carriers and the definition of early therapeutic strategies represent critical aspects of the management of CRKp infections after SCT. OI Aversa, Franco/0000-0002-8871-6817; de Fabritiis, Paolo/0000-0002-1835-0581; TIRINDELLI, MARIA CRISTINA/0000-0003-4645-4465; cudillo, laura/0000-0002-6828-9707

Published
2015

24. Allogeneic Transplant in Acute Myeloid Leukemia (AML) According to the Policy of the Rome Transplant Network (RTN): An Intention-to-Treat Analysis

Author

Arcese, W., Amadori, S., Cerretti, R., Cudillo, L., Angelis, G., Venditti, A., Buccisano, F., Cantonetti, M., Mangione, I., Andreani, M., Testi, M., Rapanotti, M. C., Fabritiis, P., Dentamaro, T., Cupelli, L., Tendas, A., Tirindelli, M. C., Annibali, O., Saltarelli, F., Mengarelli, A., Marchesi, F., Gumenyuk, S., Chierichini, A., Anaclerico, B., agostino tafuri, Montefusco, E., Ferrari, A., Naso, V., Di Piazza, F., and Picardi, A.

Published
2015

25. Unique Chemotherapy Based Reduced Intensity Conditioning Regimen for Patients Transplanted from HLA Identical Siblings, Haploidentical or Volunteer Unrelated Donors: a Prospective Study from the Rome Transplant Network

Author

Cerretti, R., Picardi, A., Cudillo, L., Angelis, G., Mariotti, B., Mengarelli, A., Marchesi, F., Mangione, I., Testi, M., Fabritiis, P., Dentamaro, T., Tirindelli, M. C., Saltarelli, F., Chierichini, A., Anaclerico, B., agostino tafuri, Ferrari, A., Di Piazza, F., and Arcese, W.

Published
2015

26. Controversies on Antibiotic Lock Technique Duration Experience with a 3-Day Course for Hematological Patients

Author

Tendas, A, Cudillo, L, Niscola, P, Cupelli, L, Picardi, A, Spagnoli, A, Scaramucci, L, Giovannini, M, Ales, M, Mirabile, M, Bove, F, Falco, S, Dentamaro, T, and Fabritiis, P

Subjects
Microbiology (medical), medicine.medical_specialty, Catheters, Time Factors, Epidemiology, Bacteremia, Vancomycin, Staphylococcus epidermidis, medicine, Humans, Settore MED/05 - Patologia Clinica, Catheter-Related Infections, Teicoplanin, Amikacin, Catheters, Indwelling, Gram-Negative Bacterial Infections, Anti-Bacterial Agents, Staphylococcal Infections, Staphylococcus haemolyticus, Antibiotic lock, Duration (project management), business.industry, Surgery, Infectious Diseases, Indwelling, Emergency medicine, business, Settore MED/15 - Malattie del Sangue
Published
2011

27. High expression levels of vla-4 (CD49d) on mobilised peripheral blood stem cells are associated with rapid engraftment in multiple myeloma patients receiving autologous transplant

Author

Bruno, A, De Meis, I, Cantoni, F, Siniscalchi, A, Velotta, V, Tendas, A, Cupelli, L, Dentamaro, T, Piccioni, D, DEL POETA, G, Ballatore, G, Tamburini, A, Suppo, G, Del Proposto, G, Adorno, G, Isacchi, G, Arcese, W, Amadori, S, Perrotti, A, DE FABRITIIS, P, and Caravita, T

Subjects
Settore MED/15 - Malattie del Sangue
Published
2012

28. [Membranous glomerulonephritis secondary to allogeneic stem cell transplant: review of the literature]

Author

Vischini G, Niscola P, Ferrannini M, Cupelli L, Tendas A, Scaramucci L, Giovannini M, Dentamaro T, Paolo de Fabritiis, and Palumbo R

Subjects
Risk Factors, Humans, Settore MED/15, Glomerulonephritis, Membranous, Stem Cell Transplantation
Abstract

Renal injury associated with hematopoietic stem cell transplant (HSCT) may be related to a combination of factors. Chronic graft-versus-host disease (cGVHD) is the most common complication of allogeneic HSCT. Although the kidneys are not considered the primary target organs for GVHD, chronic impairment of renal function may occur in 20% to 60% of HSCT patients. Membranous glomerulonephritis (MG) is the most frequent renal complication observed in patients who develop nephrotic syndrome after allogeneic HSCT. In this setting, the pathogenesis of MG is not clearly understood and the most appropriate treatment approach has not been established. In order to summarize the current knowledge on this issue, a review of the pertinent literature has been performed. The available data on MG diagnosed in patients submitted to allogeneic HSCT were identified using the MEDLINE database (last accessed: Jan 30, 2012). Fifty-nine patients with allogeneic HSCT-related MG with a median age of 43 years were identified. MG occurred at a median time of 17 months after allogeneic HSCT. A history of acute or concomitant clinically apparent cGVHD was present in 69% and 31% of cases, respectively. cGVHD, nonmyeloablative conditioning regimens, immunosuppression withdrawal, and the use of peripheral blood stem cell grafts were identified as risk factors. Among the 53 patients with available outcome data, complete remission, partial response, and inefficacy of treatment were recorded in 65%, 22% and 13% of cases, respectively. MG after allogeneic HSCT seems to be etiologically related to subclinical or overt cGVHD, which flares up after discontinuation of immunosuppression. The available measures can induce sustained long-term remission in about two-thirds of affected patients.

Published
2012

30. The potential application of the allogeneic transplant according to a widespread donor search policy: an intention-to-treat analysis from the Rome Transplant Network

Author

Picardi, A, DE FABRITIIS, P, Dentamaro, T, De Rossi, G, Caniglia, M, Petti, M, Mengarelli, A, Annino, L, Chierichini, A, Monarca, B, Ferrari, A, Avvisati, G, Tirindelli, M, Mangione, I, Pinto, R, Montefusco, E, Annibali, O, Cupelli, L, Cudillo, L, Cerretti, R, De Angelis, G, Giannotti, F, Di Veroli, A, Provenzano, I, Mirabile, M, and Arcese, W

Subjects
Settore MED/15 - Malattie del Sangue
Published
2010

31. The policy of the Rome Transplant Network (RTN), a metropolitan (2009). The Potential Application Of The Allogeneic Transplant By The Policy Of Widespread Donor Search: An Intention-To-Treat Analysis From The Rome Transplant Network

Author

Picardi, A, DE FABRITIIS, P, Dentamaro, T, De Rossi, G, Caniglia, M, Pinto Petti, M, Mengarelli, A, Annino, L, Chierichini, Monarca, B, Montefusco, E, Avvisati, G, Tirindelli, M, Mangione, I, Cudillo, L, Cerretti, R, De Angelis, G, Di Veroli, A, Provenzano, I, and Arcese, W

Subjects
Settore MED/15 - Malattie del Sangue
Published
2009

35. Successful treatment of disseminated fusariosis with high dose liposomal amphotericin-B in a patient with acute lymphoblastic leukemia [4]

Author

Cudillo, L, Tendas, A, Picardi, A, Dentamaro, T, Del Principe, Mi, Amadori, S, and De Fabritiis, P

Subjects
Adult, Male, Antifungal Agents, Time Factors, Neutrophils, Hematology, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Prognosis, X-Ray Computed, Treatment Outcome, Fusarium, Mycoses, Amphotericin B, Humans, Settore MED/05 - Patologia Clinica, Tomography, X-Ray Computed, Tomography, Settore MED/15 - Malattie del Sangue
Published
2006

38. Hematopoietic stem cell transplantation for multiple sclerosis. A retrospective multicenter study

Author

Fassas, A., Passweg, J. R., Anagnostopoulos, A., Kazis, A., Kozak, T., Havrdova, E., Carreras, E., Graus, F., Kashyap, A., Openshaw, H., Schipperus, M., Deconinck, E., Mancardi, GIOVANNI LUIGI, Marmont, A., Hansz, J., Rabusin, M., Zuazu, F. J., Besalduch, J., Dentamaro, T., Fouillard, L., Hertenstein, B., Nasa, G. L., Musso, M., Papineschi, F., Rowe, J. M., Saccardi, R., Steck, A., Kappos, L., Gratwohl, A., Tyndall, A., Samijn, J., Samign, J., Working, A. D., and Transplantation), M.

Subjects
Adult, Male, immunology/mortality/therapy, Multiple Sclerosis, Transplantation Conditioning, Hematopoietic Stem Cell Transplantation, Middle Aged, Adult, Bone Marrow Transplantation, adverse effects/mortality, CD4 Lymphocyte Count, Disease Progression, Disease-Free Survival, Female, Hematopoietic Stem Cell Mobilization, adverse effects, Hematopoietic Stem Cell Transplantation, adverse effects/mortality, Humans, Male, Middle Aged, Multiple Sclerosis, Chronic Progressive, immunology/mortality/therapy, Retrospective Studies, Transplantation Conditioning, adverse effects, Treatment Outcome, Disease-Free Survival, Hematopoietic Stem Cell Mobilization, CD4 Lymphocyte Count, adverse effects/mortality, Treatment Outcome, Disease Progression, adverse effects, Humans, Female, Bone Marrow Transplantation, Retrospective Studies
Published
2002

42. Palifermin in theManagement of Mucositis in Hematological Malignancies: Current Evidences and Future Perspectives

Author

Niscola, P., primary, Scaramucci, L., additional, Giovannini, M., additional, Ales, M., additional, Bondanini, F., additional, Cupelli, L., additional, Dentamaro, T., additional, Lamanda, M., additional, Natale, G., additional, Palumbo, R., additional, Romani, C., additional, Tendas, A., additional, Tolu, B., additional, Violo, L., additional, and de Fabritiis, P., additional

Published
2009
Full Text
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46. Treatment of Multiple Myeloma with Autologous Blood Stem Cell Transplantation. Preliminary Results of an Italian Multicentric Pilot Study

Author

Tribalto, M., primary, Papa, G., additional, Coppetelli, U., additional, Adorno, G., additional, Caravita, T., additional, Dentamaro, T., additional, Rainone, A., additional, Avvisati, G., additional, La Verde, G., additional, Leone, G., additional, Menichella, G., additional, Martelli, M., additional, Tabilio, A., additional, Iacone, A., additional, Fioritoni, G., additional, Majolino, I., additional, Scimè, R., additional, and Mandelli, F., additional

Published
1993
Full Text
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48. Bortezomib-related colon mucositis in a multiple myeloma patient.

Author

Siniscalchi A, Tendas A, Ales M, Fratoni S, Cupelli L, Dentamaro T, Scaramucci L, Giovannini M, Caravita T, Santeusanio G, Niscola P, de Fabritiis P, Siniscalchi, Agostina, Tendas, Andrea, Ales, Micaela, Fratoni, Stefano, Cupelli, Luca, Dentamaro, Teresa, Scaramucci, Laura, and Giovannini, Marco

Published
2009
Full Text
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