1. Bringing online adaptive radiotherapy to a standard C-arm linac
- Author
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Maureen L. Groot Koerkamp, Gijsbert H. Bol, Petra S. Kroon, Lean L. Krikke, Tessa Harderwijk, Annelies J. Zoetelief, Annick Scheeren, Stefan van der Vegt, Annika Plat, Jochem Hes, Ineke B.A. van Gasteren, Esmee R.T. Renders, Reijer H.A. Rutgers, Saskia W. Kok, Joost van Kaam, Geja J. Schimmel-de Kogel, Gonda G. Sikkes, Dennis Winkel, Michael J. van Rijssel, André J.M. Wopereis, Kübra Ishakoglu, Juus L. Noteboom, Jochem R.N. van der Voort van Zyp, Naomi Beck, Timo F.W. Soeterik, Sandrine M.G. van de Pol, Wietse S.C. Eppinga, Corine A. van Es, and Bas W. Raaymakers
- Subjects
Online adaptive radiotherapy (oART) ,Image-guided radiotherapy ,Cone-beam computed tomography ,Linear accelerator ,Bladder cancer ,Medical physics. Medical radiology. Nuclear medicine ,R895-920 ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Current online adaptive radiotherapy (oART) workflows require dedicated equipment. Our aim was to develop and implement an oART workflow for a C-arm linac which can be performed using standard clinically available tools. A workflow was successfully developed and implemented. Three patients receiving palliative radiotherapy for bladder cancer were treated, with 33 of 35 total fractions being delivered with the cone-beam computed tomography (CBCT)-guided oART workflow. Average oART fraction duration was 24 min from start of CBCT acquisition to end of beam on. This work shows how oART could be performed without dedicated equipment, broadening oART availability for application at existing treatment machines.
- Published
- 2024
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