186 results on '"Deniz İnal İnce"'
Search Results
2. A Comparison of Respiratory Functions, Functional Capacity and Quality of Sleep in Patients with OSAS and COPD Compared to Healthy Controls
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Ebru Çalık Kütükcü, Hakan Çalışkan, Kübra Kılıç, Naciye Vardar Yağlı, Nurel Ertürk, Melda Sağlam, Deniz İnal İnce, Hikmet Fırat, Sadık Ardıç, Melike Yüce Ege, Lütfi Çöplü, Sema Savcı, and Hülya Arıkan
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obstructive sleep apnea ,exercise test ,muscle strength ,respiratory muscles ,chronic obstructive pulmonary disease ,Medicine ,Medicine (General) ,R5-920 - Abstract
Objective:The purpose of this study was to compare the respiratory functions, exercise performance, and quality of sleep in patients with Obstructive Sleep Apnea syndrome (OSAS) and Chronic Obstructive Pulmonary disease (COPD) compared to healthy individuals.Materials and Methods:Seventeen patients with OSAS (12 M, 5 F), 24 patients with COPD (20 M, 4 F) and 20 healthy subjects (15 M, 5 F) participated in this cross-sectional study. Respiratory function and muscle strength tests were performed. Knee extensors, shoulder abductors, and hand grip strength were measured in patients with OSAS and COPD using a digital hand-held dynamometer. Exercise performance was evaluated using a 6-minute walk test (6MWT), and sleep quality was assessed by the Pittsburgh Sleep Quality index (PSQI).Results:The 6MWT distance, 6MWT% distance, actual and percentage values of shoulder abductors muscle strength of patients with COPD were significantly lower than those of the OSAS group (p
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- 2020
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3. The Relationship Between the Physical Activity Level and Fatigue Perception, Quality of Life and Psychological Status in Patients with Obstructive Sleep Apnea Syndrome
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Hakan Çalışkan, Nurel Ertürk, Ebru Çalık Kütükçü, Hülya Arıkan, Naciye Vardar Yağlı, Melda Sağlam, Hikmet Fırat, Sadık Ardıç, Deniz İnal İnce, and Melike Yüce Ege
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Obstructive sleep apnea ,apnea-hypopnea index ,exercise test ,anxiety ,sedentary lifestyle ,Medicine ,Medicine (General) ,R5-920 - Abstract
Objective:Currently, there is a need for research that examines factors which affect physical activity (PA) participation in Obstructive Sleep Apnea syndrome (OSAS) patients. The purpose of this study was to investigate the relationship between the PA level and daytime sleepiness, fatigue perception, quality of life, and psychological status in patients with OSAS.Materials and Methods:This cross-sectional study involved 38 patients with OSAS between the ages of 30-60 years. The PA level was determined using the Turkish version of the International Physical Activity Questionnaire (IPAQ). Quality of life was evaluated by the Functional Outcomes of Sleep Questionnaire and Nottingham Health Profile (NHP). The Epworth Sleepiness Scale (ESS) was used for evaluation of the sleepiness status. The fatigue perception of the patients was evaluated by the Fatigue Impact Scale (FIS) and the Fatigue Severity Scale (FSS).Results:According to IPAQ classification, 44.7% of patients were inactive. A marked correlation was observed between IPAQ-total score with ESS score (r =-0.493, p=0.002), Hospital Anxiety and Depression Scale-Anxiety score (r=-0.338, p=0.041), NHP-social isolation score (r=-0.406, p=0.013), FIS-physical score (r=-0.404, p=0.013), and FISpsychosocial score (r=-0.411, p=0.012).Conclusion:This study showed that the total amount of PA in patients with OSAS is closely related to excessive daytime sleepiness, anxiety level, social isolation and effects of fatigue on physical and psychosocial functions.
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- 2019
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4. Astımlı Hastalarda ve Sağlıklı Kişilerde Dispne Düzeyinin Karşılaştırılması
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Hazal Sonbahar, Deniz İnal İnce, Melda Sağlam, Naciye Vardar Yağlı, Ebru Çalık Kütükcü, Hülya Arıkan, Cemile Bozdemir Özel, Aslıhan Çakmak, Özge Müezzinoğlu, and Gül Karakaya
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asthma ,dyspnea ,bronchoconstruction ,Other systems of medicine ,RZ201-999 ,Miscellaneous systems and treatments ,RZ409.7-999 ,Nutritional diseases. Deficiency diseases ,RC620-627 - Abstract
Purpose: Bronchial asthma is a chronic disease which characterized with reversible airway inflammation and intermittent symptoms. Dyspnea which develops due to ventilation-perfusion mismatch is one of the most important symptom of asthma. The aim of this study was to investigate the difference of dyspnea sensation between the asthma patients and healthy individuals. Materials and Methods: A total of 20 subjects aged 18-65 years people including 10 patients with bronchial asthma (age =39.6±15.4 years), 10 healthy individuals (age=39.1±6.9 years)were included in the study. Physical characteristics and pulmonary function parameters were recorded. Dyspnea was determined using the modified Modifiye Medical Research Council (MMRC) scale. Results: There was no significant difference in age, height, weight and body mass index between asthmatics and healthy subjects (p>0.05). There were statistically significant differences in forced expiratory volume in one second (p
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- 2014
5. Health-Promoting Behaviors, Health Literacy, and Levels of Knowledge about Smoking-Related Diseases among Smokers and Non-smokers: A Cross-Sectional Study
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Cihat Celebi, Ebru Calik-Kutukcu, Melda Saglam, Cemile Bozdemir-Ozel, Deniz Inal-Ince, and Naciye Vardar-Yagli
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smoking ,physical activity ,healthy lifestyle ,health literacy ,Diseases of the respiratory system ,RC705-779 - Abstract
Background For generations, cigarette smoking has presented an important public health concern. This study aimed to compare the health-promoting behavior, exercise capacity, physical activity level, health literacy, and knowledge level of smoking-related diseases between smokers and non-smokers. Methods The study included 71 smokers (mean age, 32.69±8.55 years) and 72 non-smokers (mean age, 31.88±9.94 years) between the ages of 20 and 60 years. Assessments included a 6-minute walking test (6MWT), Godin Leisure-Time Physical Activity Questionnaire, Health-Promoting Lifestyle Profile II (HPLP-II), Cardiovascular Risk Factors Knowledge Level Scale (CARRF-KL), Asthma/COPD Awareness Questionnaire, the World Health Organization Quality of Life-Bref questionnaire (WHOQoL-Bref [TR]), and Health Literacy Questionnaire (HLQ). Results The results from the study show that the number of coronary artery disease risk factors measured significantly higher among the smoker group members when compared to that of the non-smoker group members (p=0.001). Smokers had significantly lower %6MWT distance than non-smokers (84.83±4.72 and 93.45±7.16, respectively; p0.05). Additionally, while only forty-one smokers (57.7%) were active, 48 of the non-smoker group was active (66.7%). Conclusion Smokers suffer greater negative effects to their exercise capacity in comparison to non-smokers. Although smokers and non-smokers have similar levels of health literacy and similar levels of knowledge about cardiovascular disease risk factors and obstructive lung diseases, health professionals could continue to further increase individuals’ awareness of smoking-related risk factors and continue to emphasize the importance of physical activity and exercise for protecting cardiopulmonary health.
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- 2021
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6. Assessment of exercise capacity using field walking tests in patients after the Fontan procedure: A case–control study
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Haluk Tekerlek, Melda Saglam, Ali Cem Kucukdagli, Hayrettin Hakan Aykan, Naciye Vardar-Yagli, Ebru Calik-Kutukcu, Deniz Inal-Ince, and Tevfik Karagoz
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Pulmonary and Respiratory Medicine ,Cardiology and Cardiovascular Medicine ,Critical Care and Intensive Care Medicine - Published
- 2023
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7. Metabolomic, oxidative, and inflammatory responses to acute exercise in chronic obstructive pulmonary disease
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Aslihan Cakmak, Emirhan Nemutlu, Samiye Yabanoglu-Ciftci, Ipek Baysal, Elif Kocaaga, Lutfi Coplu, and Deniz Inal-Ince
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Pulmonary and Respiratory Medicine ,Cardiology and Cardiovascular Medicine ,Critical Care and Intensive Care Medicine - Published
- 2023
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8. Impaired Balance and Gait Characteristics in Patients With Chronic Heart Failure
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Emine Burcu, Ozcan, Melda, Saglam, Naciye, Vardar-Yagli, Ebru, Calik-Kutukcu, Deniz, Inal-Ince, Meltem, Altinsoy, and Ergun Baris, Kaya
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Heart Failure ,Pulmonary and Respiratory Medicine ,Cross-Sectional Studies ,Hand Strength ,Chronic Disease ,Humans ,Nervous System Diseases ,Cardiology and Cardiovascular Medicine ,Gait ,Postural Balance - Abstract
Heart failure affects most systems of the body and causes various problems in patients. Balance deficits and gait deviations can be a result of these effects. There is little information in the literature about balance and gait parameters in chronic heart failure (CHF). This study aimed to investigate balance abnormalities together with gait deficits for possible associations in patients with CHF and compare them to healthy controls.Twenty-two (22) patients with CHF (59±2.5 years) and 22 age- and gender-matched healthy subjects (59.4±6.8 years) participated in the study. This study is a cross-sectional/comparison study. Balance was evaluated using the Activity-Specific Balance Confidence Scale (ABC) and the Mini-Balance Evaluation Systems Test (Mini-BESTest) balance battery, which includes the timed up-and-go test (TUG) and dual-task TUG. Gait analysis was performed using a Biodex Gait Trainer. Peripheral muscle strength (quadriceps muscle and handgrip strength) was assessed using a hand dynamometer and exercise capacity using the six-minute walk test (6MWT).The CHF patients had significantly lower Mini-BESTest total, reactive postural control, and gait stability scores, significantly longer TUG/dual-task TUG time, and lower ABC score compared to the healthy control group (p0.05). Chronic heart failure patients also showed significantly lower gait speed, stride length, gait cycle and step length (p0.05). Dominant-side quadriceps muscle and handgrip strength and 6MWT distance were significantly reduced in CHF (p0.05). Anticipatory postural adjustments and sensory orientation did not differ between groups.Our study demonstrated impaired balance and gait performance and reduced muscle strength and exercise capacity in patients with CHF. Cardiac rehabilitation including balance and walking training should be planned for CHF patients to eliminate balance disorders, gait impairment and prevent falls in this patient group.
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- 2022
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9. Active video gaming in primary ciliary dyskinesia: a randomized controlled trial
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Hazal Sonbahar-Ulu, Deniz Inal-Ince, Melda Saglam, Aslihan Cakmak, Naciye Vardar-Yagli, Ebru Calik-Kutukcu, Erkan Sumer, and Ugur Ozcelik
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Video Games ,Kartagener Syndrome ,Activities of Daily Living ,Pediatrics, Perinatology and Child Health ,Quality of Life ,Humans ,Muscle Strength ,Child ,Exergaming - Abstract
Primary ciliary dyskinesia (PCD) impairs pulmonary function, respiratory and peripheral muscle strength, and exercise capacity. We aimed to investigate the effects of active video games (AVGs) on pulmonary function, respiratory and peripheral muscle strength, exercise capacity, muscle oxygenation (SMO
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- 2022
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10. Body functions and structure, activity, and participation limitations of adult cystic fibrosis patients under the international classification of functioning, disability, and health framework
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Rabia Bagci, Naciye Vardar-Yagli, Melda Saglam, Ebru Calik Kutukcu, Deniz Inal-Ince, Fatma Sener, and Ebru Damadoglu
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Physical Therapy, Sports Therapy and Rehabilitation - Published
- 2022
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11. Upper Extremity Exercise Capacity and Activities of Daily Living in Individuals with Bronchiectasis Versus Healthy Controls
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Aslihan Cakmak, Elif Kocaaga, Hazal Sonbahar-Ulu, Deniz Inal-Ince, Naciye Vardar-Yagli, Ebru Calik-Kutukcu, Melda Saglam, and Lutfi Coplu
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Physical Therapy, Sports Therapy and Rehabilitation - Abstract
Objective The purpose of this study was to compare the upper extremity exercise capacity and activities of daily living (ADLs) in individuals with bronchiectasis and controls. Methods Twenty-four individuals with bronchiectasis and 24 healthy controls were assessed for upper extremity exercise capacity (6-minute pegboard and ring test [6PBRT]) and ADLs (Glittre ADL test). Energy expenditure was measured using a wearable metabolic monitor during the Glittre ADL test. Results The mean 6PBRT score of individuals with bronchiectasis was significantly lower than the mean score of controls (196.50 [SD = 51.75] versus 243.00 [SD = 29.76] number of rings). The Glittre ADL test duration was significantly higher in individuals with bronchiectasis compared with controls (3.54 [SD = 1.53] versus 2.36 [SD = 0.18] min), despite similar energy expenditure during the Glittre ADL test between the groups (17.67 [SD = 5.28] kcal in individuals with bronchiectasis versus 18.13 [SD = 5.71] kcal in controls). The 6PBRT score and the Glittre ADL test duration were negatively correlated in individuals with bronchiectasis (r = −0.694). Conclusions The individuals with bronchiectasis had reduced upper extremity exercise capacity compared with healthy controls. Energy expenditure during ADLs was similar between individuals with bronchiectasis and healthy controls, despite lower ADL performance in individuals with bronchiectasis. The upper extremity exercise capacity and ADLs are related in individuals with bronchiectasis. Given the relationship between upper extremity exercise capacity and ADLs in bronchiectasis, inclusion of upper extremity exercise training to pulmonary rehabilitation programs should be considered. Impact Considering the impairment of upper extremity exercise capacity and ADLs in individuals with bronchiectasis highlights the necessity to tailor preventive strategies and preclude further unfavorable effects. Lay Summary Bronchiectasis may cause deterioration in upper extremity exercise capacity and ADLs. The assessment of upper exercise capacity and ADLs by physical therapists in individuals with bronchiectasis may be useful for designing comprehensive rehabilitation programs and thus the management of bronchiectasis.
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- 2023
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12. Obstrüktif uyku apne sendromu olan kadın ve erkeklerde respiratuar kas fonksiyonu, solunum fonksiyonları ve egzersiz kapasitesinin incelenmesi
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Şahveren ÇAKARTAŞ, Deniz İNAL İNCE, Bahar KAYMAKAMZADE, Melda SAĞLAM, and Deniz İNCE
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Amaç: Obstrüktif uyku apne sendromu (OUAS) erkeklerde kadınlardan daha yaygın görülmektedir. Bu çalışmada OUAS tanısı almış kadın ve erkek hastalarda elektromyografik respiratuar kas fonksiyonu, solunum kas kuvveti, solunum fonksiyonları ve egzersiz kapasitenin karşılaştırılması amaçlandı. Yöntem: Çalışmaya 19 OUAS olgusu (yaş ortalaması=54,68±13,15 yıl, 10 E, 9 K) dahil edildi. Apne/hipopne indeksi (AHİ) ve en düşük oksijen satürasyonu (SpO2) değerleri kaydedildi. Solunum fonksiyon testinde birinci saniyedeki zorlu ekspirasyon volümü (FEV1) ve zorlu vital kapasite (FVC) değerleri kaydedildi. Maksimal inspiratuar basınç (MIP) ve maksimal ekspiratuar basınç (MEP) ölçüldü. Respiratuar kas fonksiyonu, diyafragma yüzeyel elektromiyografi (EMGdi) ve sternoklediomasteoid elektromiyografi (EMGskm) ölçümleri ile değerlendirildi. Altı dakika yürüme testi ve Pittsburgh Uyku Kalitesi İndeksi (PUKİ) uygulandı. Bulgular: Erkek OUAS hastalarının FEV1, FVC, %MIP, MEP, EMGdi, EMGskm ve 6DYT mesafesi değerleri kadın olgulardan anlamlı olarak daha yüksekti (p
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- 2022
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13. Exercise performance in children and adolescents with cystic fibrosis with and without abnormal glucose tolerance: a single center cross-sectional study
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Elif Kocaaga, Deniz Inal-Ince, Deniz Dogru, Ayfer Alikasifoglu, Dilber Ademhan-Tural, Cemile Bozdemir-Ozel, Ebru Calik-Kutukcu, Melda Saglam, Naciye Vardar-Yagli, and Nagehan Emiralioglu
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Physical Therapy, Sports Therapy and Rehabilitation - Abstract
Abnormal glucose tolerance (AGT) in cystic fibrosis (CF) affects lung function and clinical parameters, including aerobic fitness. However, its effects on physical activity level (PAL), anaerobic power (AP), and muscle strength (MS) in children and adolescents are unknown.To investigate aerobic fitness, PAL, AP, and MS in pediatric patients with mild-to-moderate CF and AGT.The study included children and adolescents with CF aged 10-18 years. Participants underwent a pulmonary function test, quadriceps, and handgrip MS measurement, vertical jump test to assess AP, and six-minute walk test (6MWT) to assess aerobic fitness. Bouchard's Three-Day Physical Activity record was used to determine PAL.Height z-score (p = .006), 6MWT (p = .024), handgrip (p = .028), quadriceps MS (p = .044), and AP (p = .036) were significantly lower in AGT (n = 21) than normal glucose tolerance (NGT) (n = 19). In the AGT group, glycosylated hemoglobin (HbA1c) was significantly associated with forced expiratory volume in one second (FEVMeasures of aerobic fitness, MS, and AP are lower in AGT, but after adjusting for height and FEV
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- 2022
14. Health-Promoting Behaviors, Health Literacy, and Levels of Knowledge about Smoking-Related Diseases among Smokers and Non-smokers: A Cross-Sectional Study
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Cemile Bozdemir-Ozel, Naciye Vardar-Yagli, Cihat Celebi, Deniz Inal-Ince, Melda Saglam, and Ebru Calik-Kutukcu
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Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Cross-sectional study ,Physical activity ,physical activity ,Health literacy ,smoking ,03 medical and health sciences ,0302 clinical medicine ,healthy lifestyle ,Environmental health ,medicine ,030212 general & internal medicine ,Asthma ,lcsh:RC705-779 ,COPD ,business.industry ,Public health ,Knowledge level ,lcsh:Diseases of the respiratory system ,medicine.disease ,Physical activity level ,Miscellaneous ,respiratory tract diseases ,Infectious Diseases ,030228 respiratory system ,behavior and behavior mechanisms ,Original Article ,business ,health literacy - Abstract
Background For generations, cigarette smoking has presented an important public health concern. This study aimed to compare the health-promoting behavior, exercise capacity, physical activity level, health literacy, and knowledge level of smoking-related diseases between smokers and non-smokers. Methods The study included 71 smokers (mean age, 32.69±8.55 years) and 72 non-smokers (mean age, 31.88±9.94 years) between the ages of 20 and 60 years. Assessments included a 6-minute walking test (6MWT), Godin Leisure-Time Physical Activity Questionnaire, Health-Promoting Lifestyle Profile II (HPLP-II), Cardiovascular Risk Factors Knowledge Level Scale (CARRF-KL), Asthma/COPD Awareness Questionnaire, the World Health Organization Quality of Life-Bref questionnaire (WHOQoL-Bref [TR]), and Health Literacy Questionnaire (HLQ). Results The results from the study show that the number of coronary artery disease risk factors measured significantly higher among the smoker group members when compared to that of the non-smoker group members (p=0.001). Smokers had significantly lower %6MWT distance than non-smokers (84.83±4.72 and 93.45±7.16, respectively; p0.05). Additionally, while only forty-one smokers (57.7%) were active, 48 of the non-smoker group was active (66.7%). Conclusion Smokers suffer greater negative effects to their exercise capacity in comparison to non-smokers. Although smokers and non-smokers have similar levels of health literacy and similar levels of knowledge about cardiovascular disease risk factors and obstructive lung diseases, health professionals could continue to further increase individuals’ awareness of smoking-related risk factors and continue to emphasize the importance of physical activity and exercise for protecting cardiopulmonary health.
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- 2021
15. Impaired exercise capacity in electrostatic polyester powder paint workers
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Deniz Inal-Ince, Ferhan Soyuer, Cihangir Acik, Ukbe Sirayder, Soyuer, Ferhan, and 37765 [Soyuer, Ferhan]
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Adult ,Male ,medicine.medical_specialty ,Mesleki akciğer hastalığı ,Polyesters ,Health, Toxicology and Mutagenesis ,Kimyasal silah ,Walking ,010501 environmental sciences ,Toxicology ,01 natural sciences ,Young Adult ,03 medical and health sciences ,Human health ,0302 clinical medicine ,Occupational Exposure ,Paint ,Exercise capacity ,Humans ,Medicine ,Occupational pulmonary disease ,Chemical agent ,Muscle Strength ,Akciğer fonksiyonu ,Lung function ,0105 earth and related environmental sciences ,Exercise Tolerance ,business.industry ,Soluma toksisitesi ,respiratory system ,Respiratory Muscles ,respiratory tract diseases ,Respiratory Function Tests ,Polyester ,Egzersiz kapasitesi ,030228 respiratory system ,Case-Control Studies ,Chemical agents ,Physical therapy ,Inhalation toxicity ,Powders ,business ,circulatory and respiratory physiology - Abstract
Purpose: Limited number of studies investigated the effects of Electrostatic powder paints (EPP) on human health. We investigated the effects of EPP exposure on lung function, exercise capacity, and quality of life, and the factors determining exercise capacity in EPP workers. Methods: Fifty-four male EPP workers and 54 age-matched healthy male individuals (control group) were included. Lung function and respiratory muscle strength were measured. The lower limit of normal (LLN) cut-points for FEV1 and FEV1/FVC were calculated. An EPT was used to evaluate bronchial hyperactivity. The handgrip and quadriceps muscle strength were evaluated using a hand-held dynamometer. An ISWT was used to determine exercise capacity. The physical activity level was questioned using the IPAQ. The SGRQ and NHP were used to assessing respiratory specific and general quality of life, respectively. Results: Duration of work, FEV1, MIP, handgrip strength, and ISWT distance were significantly lower, and the change in FEV1 after EPT and %HRmax were significantly higher in the EPP group compared to the control group (p < 0.05). There were no subjects with a < LLN for FEV1 and FEV1/FVC in both groups. In the EPP group, ISWT distance was significantly related to age, height, duration of work, FEV1, change in FEV1 after EPT, MIP, MEP, handgrip strength, IPAQ, SGRQ, and NHP total scores (p < 0.05). The change in FEV1 after EPT, MIP, and duration of work explained % 62 of the variance in the ISWT distance (p < 0.001). Conclusions: Changes in lung function based on LLN for the FEV1 and FEV1/FVC were not clinically relevant in EPP workers. Exercise capacity is impaired in EPP workers. Degree of exercise-induced bronchospasm, inspiratory muscle strength, and duration of work are the determinants of exercise capacity in EPP workers. No sponsor
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- 2021
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16. Long-Term Characteristics of Severe COVID-19: Respiratory Function, Functional Capacity, and Quality of Life
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Ukbe Sirayder, Deniz Inal-Ince, Busra Kepenek-Varol, and Cihangir Acik
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Adult ,Health, Toxicology and Mutagenesis ,Time and Motion Studies ,Public Health, Environmental and Occupational Health ,Quality of Life ,Aftercare ,COVID-19 ,Humans ,Postural Balance ,Fatigue ,Patient Discharge ,lung function ,post-COVID-19 ,fibrosis ,functional capacity ,fatigue ,quality of life - Abstract
© 2022 by the authors. Licensee MDPI, Basel, Switzerland.Recovery from pneumonia takes around 3–6 months in individuals with severe COVID-19. In order to detect the isolated damage caused by COVID-19, the 6-month period must pass after the recoveries. However, to our knowledge, no published study analyzes a comprehensive evaluation of individuals with severe COVID-19 after 6 months. We aimed to evaluate long-term consequences of severe COVID patients by comparing respiratory function, functional capacity, quality of life, fatigue, and balance 6 months after the intensive care unit (ICU) discharge with healthy individuals. Method: 26 post-COVID adult patients and 26 healthy individuals (control group) were included in this study. Physical characteristics of both groups and patients’ ICU data, including APACHE II scores, were recorded. Lung function, respiratory, and peripheral muscle strength were measured. The lower limit of normal (LLN) cutoff points for forced vital capacity (FVC) and forced expiratory volume in one second (FEV1) were calculated. A 6-minute walk test (6MWT) was used to assess functional capacity. Time Up and Go test (TUG) with a stadiometer was performed for balance evaluation. Quality of life was evaluated using Nottingham Health Profile (NHP) and St George Respiratory Questionnaire (SGRQ). Results: Percent predicted FVC and FEV1, 6MWT distance, change in oxygen saturation (SpO2) during 6MWT, were lower and NHP, SGRQ, FSS scores and TUG findings were higher in the COVID group than the control group (p < 0.05). The FVC of nine individuals and the FEV1 value of seven individuals in the COVID-19 group were below the LLN values. A moderate correlation was found between ICU length of stay and APACHE II scores with FVC, FEV1, 6MWT distance, and change in SpO2 values in the COVID-19 patients (p < 0.05). Conclusion: Respiratory function, functional capacity, quality of life, and fatigue levels of the individuals with severe COVID-19 infection are impaired at 6 months after ICU discharge. Impaired lung function might be associated with severe inflammation, which starts during the acute infection process and the fibrous tissue during the healing process, impairing lung compliance and diffusion capacity. Infiltration of coronavirus and inflammatory cytokines into the cerebrum and muscle might have increased fatigue and decreased functional capacity. Overall, our study suggests that severe COVID patients need post-discharge care even after 6 months of recovery.
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- 2022
17. FUNCTIONAL INDEPENDENCE AND MUSCLE STRENGTH IN ACUTE RESPIRATORY FAILURE WITH AND WITHOUT NON-INVASIVE MECHANICAL VENTILATORY SUPPORT
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Şahveren Çakartaş, Hülya Arikan, Meral Boşnak Güçlü, Melda Sağlam, Sema Savci, Arzu Topeli Iskit, Naciye Vardar Yağli, Deniz Inal Ince, and Ebru Calik Kutukcu
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Intensive care,muscle strength,noninvasive ventilation ,Rehabilitation ,Rehabilitasyon ,Physical Therapy, Sports Therapy and Rehabilitation ,Orthopedics and Sports Medicine ,Yoğun Bakım,Kas Kuvveti,Noninvaziv Ventilasyon,Solunum Yetmezliği - Abstract
Amaç: Akut solunum yetmezliği (ASY) sürecinde kas zayıflığı gelişimi sıktır. Bu çalışmanda yoğun bakımda ASY nedeni ile tek başına standart medikal tedavi (SMT) ve SMT’ye ek olarak noninvaziv mekanik ventilasyon (NIV) uygulanan olgularda kas kuvveti ve fonksiyonel bağımsızlığı karşılaştırılmak amaçlandı. Yöntem: Çalışmaya ASY ile izlenen 32 olgu (19 NIV ve 13 SMT) dahil edildi. Olguların özellikleri kaydedildi. Periferal kas kuvveti için Medical Research Council Skalası (MRC) kullanıldı ve el kavrama kuvveti ölçüldü. Fonksiyonel bağımsızlık düzeyi Barthel İndeksi (Bİ) ile değerlendirildi. Sonuçlar: NIV grubunda proksimal kas kuvveti (omuz abduktorleri) distal ekstremite kas kuvvetinden (el bileği ekstansorleri) anlamlı olarak daha düşüktü (p=0,030). Her iki grupta, proksimal alt ekstremite kas kuvveti (kalça fleksiyonu), distal ekstremite kas kuvveti (ayak bileği)’nden anlamlı olarak daha azdı (p=0,002). NIV grubunun Bİ toplam puanı SMT grubundan anlamlı olarak daha düşüktü (p=0,016). Bİ puanı, MRC toplam puanı (r=0,633) ve el kavrama kuvveti (r=0,629) ile ilişkiliydi (p, Purpose: Development of muscle weakness is common in the course of acute respiratory failure (ARF). This study aimed to compare muscle strength and physical function in subjects with ARF undergoing noninvasive mechanical ventilation (NIV) added to standard medical treatment (SMT) and SMT only in the intensive care unit. Methods: Thirty-two subjects with ARF (19 NIV and 13 SMT) were included. Subject characteristics were recorded. Peripheral muscle strength was measured using the Medical Research Council Scale (MRC) and handgrip strength. Functional independence was evaluated using the Barthel Index (BI). Results: In the NIV group, proximal muscle strength (shoulder abduction) was significantly lower than distal limb strength (wrist extension) (p=0.030). In both groups, proximal lower limb strength (hip flexion) was also significantly lower than distal limb strength (ankle dorsiflexion) (p=0.002). The BI total score was significantly lower in the NIV group than that of the SMT group (p=0.016). The BI score was significantly related to the MRC sum score (r=0.633) and handgrip strength (r=0.629, p
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- 2020
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18. Sustainable inspiratory pressure and incremental threshold loading for respiratory muscle endurance in chronic obstructive pulmonary disease: A pilot study
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Deniz Inal-Ince, Selda Gokcen, Hulya Arikan, Naciye Vardar-Yagli, Ebru Calik-Kutukcu, Melda Saglam, and Lutfi Coplu
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Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Pulmonary disease ,Pilot Projects ,Pulmonary function testing ,Pulmonary Disease, Chronic Obstructive ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,medicine ,Respiratory muscle ,Humans ,Immunology and Allergy ,030212 general & internal medicine ,Expiratory muscle ,Genetics (clinical) ,COPD ,Muscle fatigue ,business.industry ,Reproducibility of Results ,medicine.disease ,Respiratory Muscles ,Respiratory Function Tests ,030228 respiratory system ,Walk test ,Assessment methods ,Physical Endurance ,Cardiology ,business - Abstract
INTRODUCTION A prolonged mismatch between the demand for respiratory muscle work and the capacity to meet that demand in chronic obstructive pulmonary disease (COPD) can result in symptoms of dyspnea and the development of muscle fatigue. OBJECTIVES The purpose of this study was to compare two different respiratory muscle endurance assessment methods of sustainable inspiratory pressure (SIP) and incremental threshold loading (ITL) in COPD. METHODS Thirty-four patients diagnosed with COPD were included in the study. Physical and demographic characteristics of the subjects were recorded. Pulmonary function testing (PFT), modified Medical Research Council (MMRC) dyspnea scale, COPD assessment test, inspiratory and expiratory muscle strength (MIP and MEP, respectively) measurement and six-minute walk test (6MWT) were used to assess subjects. Two different respiratory muscle endurance tests (SIP and ITL) were performed within 48 hours apart, and each test was repeated two times on the same day. RESULTS There was no correlation between the SIP and ITL tests (r = 0.069, P = .699). According to the test-retest reliability analysis, both tests were reproducible (ICC = 0.843; P < .001 for SIP, ICC = 0.905; P < .001 for ITL). Finding no differences between repeated tests showed that tests are not affected by learning effect. CONCLUSION The SIP and ITL tests are used for the same purpose but have different characteristics. Regarding the relationship between the other parameters and tests, the ITL is well tolerated and reflects the differences in respiratory muscle endurance better.
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- 2020
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19. Motor repertoire is age-inadequate in infants with cystic fibrosis
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Ugur Ozcelik, Deniz Inal-Ince, Jale Karakaya, Haluk Tekerlek, Sanem Eryilmaz-Polat, Aysu Kahraman, Akmer Mutlu, and Ayşe Livanelioğlu
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Male ,Pediatrics ,medicine.medical_specialty ,Cystic Fibrosis ,Genotype ,Movement ,Video Recording ,Cystic Fibrosis Transmembrane Conductance Regulator ,Severity of Illness Index ,Cystic fibrosis ,03 medical and health sciences ,0302 clinical medicine ,Disease severity ,Negatively associated ,030225 pediatrics ,Humans ,Medicine ,Vitamin A ,Genetic Association Studies ,reproductive and urinary physiology ,Genetic testing ,Video recording ,medicine.diagnostic_test ,business.industry ,Repertoire ,Age Factors ,Infant ,medicine.disease ,General movements ,Hospitalization ,Phenotype ,Motor Skills ,Case-Control Studies ,Mutation ,embryonic structures ,Pediatrics, Perinatology and Child Health ,Fidgety movements ,Female ,business ,030217 neurology & neurosurgery - Abstract
BACKGROUND General movements (GMs) in infants occur as fidgety movements (FMs) between postterm 9 and 20 weeks. We aimed to evaluate FMs and motor repertoire in infants with cystic fibrosis (CF) and their relation with clinical findings. METHODS Demographic and clinical characteristics were recorded. FMs and motor repertoire were analyzed from a 5-min video recording of each infant. Videos were rated based on the Prechtl General Movement Assessment and motor optimality score (MOS) was calculated. RESULTS The analysis included 18 infants with CF and 20 healthy infants at postterm age of 3-5 months. MOS was significantly lower in the infants with CF compared to controls (p
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- 2020
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20. Visuomotor reaction time and dynamic balance in children with cystic fibrosis and non‐cystic fibrosis bronchiectasis: A case‐control study
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Jan Dik, Deniz Dogru, Haluk Tekerlek, Sanem Eryilmaz-Polat, Deniz Inal-Ince, Naciye Vardar-Yagli, Hülya Arikan, Melda Saglam, and Ebru Calik-Kutukcu
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Male ,Pulmonary and Respiratory Medicine ,Pediatrics ,medicine.medical_specialty ,Adolescent ,Cystic Fibrosis ,medicine.medical_treatment ,Cystic fibrosis ,Pulmonary function testing ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,law ,030225 pediatrics ,Reaction Time ,medicine ,Humans ,Pulmonary rehabilitation ,Child ,Dynamic balance ,Postural Balance ,Balance (ability) ,Exercise Tolerance ,Bronchiectasis ,business.industry ,Case-control study ,medicine.disease ,030228 respiratory system ,Spirometry ,Case-Control Studies ,Pediatrics, Perinatology and Child Health ,Female ,business ,Spirometer - Abstract
Objective Extrapulmonary involvement such as balance and reaction time is unclear in cystic fibrosis (CF) patients. The aim of this study was to evaluate visuomotor reaction time (VMRT) and dynamic balance in children with CF and non-CF bronchiectasis compared to healthy children. Design/methods Demographic and clinical characteristics were recorded. All children were evaluated with pulmonary function test (PFT) using a spirometer, incremental shuttle walk test (ISWT) for exercise capacity, Fitlight Trainer for VMRT, and functional reach test (FRT) for dynamic balance. Results Fourteen children with CF (10.71 ± 2.94 years, 7 females), 17 children with non-CF bronchiectasis (12.75 ± 2.81 years, 8 females), and 21 healthy children (11.36 ± 3.28 years, 11 females) were included. Children with CF had longer total VMRT (P = .027), poorer FRT performance (P = .001), and shorter ISWT distances (P = .03) compared to the children with non-CF bronchiectasis and controls. Although total VMRT was longest in the CF group, there was no significant difference in mean VMRT among the CF, non-CF bronchiectasis, and control groups (P > .05). Conclusion Dynamic balance and VMRT show greater impairment in children with CF than in children with non-CF bronchiectasis compared to healthy controls. Our findings suggest that VMRT and dynamic balance should be taken into consideration for assessments and exercise programs in pulmonary rehabilitation.
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- 2020
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21. Levels of Physical Activity and Physical Fitness in Pediatric Pacemaker Patients: A Cross-Sectional Study
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Deniz Inal-Ince, Ebru Calik-Kutukcu, Tevfik Karagöz, Sena Teber, Naciye Vardar-Yagli, Melda Saglam, Hülya Arikan, Aslihan Cakmak, and İlker Ertuğrul
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Male ,Pacemaker, Artificial ,medicine.medical_specialty ,Adolescent ,Cross-sectional study ,Physical fitness ,Physical activity ,030204 cardiovascular system & hematology ,03 medical and health sciences ,0302 clinical medicine ,Accelerometry ,medicine ,Humans ,Patient group ,Child ,Exercise ,business.industry ,Healthy subjects ,Arrhythmias, Cardiac ,Vascular surgery ,Cardiac surgery ,Cross-Sectional Studies ,Fitness test ,030228 respiratory system ,Physical Fitness ,Pediatrics, Perinatology and Child Health ,Physical therapy ,Female ,Sedentary Behavior ,Energy Metabolism ,Cardiology and Cardiovascular Medicine ,business - Abstract
Children with heart diseases have reduced physical activity (PA) levels relative to their peers, which in turn increases cardiovascular risk. To the best of our knowledge, physical fitness and objectively measured PA levels have not been previously studied in children with pacemakers. We evaluated PA levels and physical fitness in pediatric pacemaker patients compared to their healthy peers. Twenty-eight pediatric patients with pacemakers (15 female, 13 male; mean age 13.43 ± 3.68 years) and 24 healthy subjects (14 female, 10 male; mean age 13.08 ± 3.67 years) were included. Physical fitness was assessed using the Munich Fitness Test (MFT). SenseWear Armband metabolic Holter device was used to record the PA for 7 consecutive days. MFT total and sub-parameter scores were significantly lower in the patient group (p 0.05). Patients' total and active energy expenditure, PA level, total distance, number of steps, and vigorous PA were significantly lower than those of healthy children (p 0.05). Sedentary activity and light, moderate, and very vigorous PA durations were similar in both groups (p 0.05). Duration of mean moderate to vigorous PA was higher than 60 min/day recommended in PA guidelines in both patients and healthy subjects. These results provide initial data on PA and fitness in children with pacemakers and suggest that physical fitness and activity levels in children with pacemakers are lower than in healthy peers. Appropriate exercise programs may improve PA levels in pediatric pacemaker patients. Awareness of the importance of PA should be raised among the parents and families of these children.
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- 2020
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22. Association between 6 min pegboard and ring test and arm performance in GOLD stage II–III patients
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Çiğdem Öksüz, Ebru Calik-Kutukcu, Lutfi Coplu, Deniz Inal-Ince, Naciye Vardar-Yagli, Hulya Arikan, Sema Savci, Melda Saglam, and Tülin Düger
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medicine.medical_specialty ,COPD ,Activities of daily living ,business.industry ,General Medicine ,030204 cardiovascular system & hematology ,Hemoglobin levels ,medicine.disease ,Test (assessment) ,03 medical and health sciences ,0302 clinical medicine ,Arm exercise ,Physical therapy ,medicine ,In patient ,030212 general & internal medicine ,business ,human activities ,Gold stage ,Blood drawing - Abstract
Background The 6 min pegboard and ring test (6PBRT) is a valid and reproducible test of unsupported arm exercise endurance. The aim of this study was to determine the associations between the 6PBRT, activities of daily living (ADL) and hemoglobin levels in chronic obstructive pulmonary disease (COPD). Methods This study included 40 stable patients with COPD. All participants underwent the 6PBRT, peripheral venous blood sampling, arm ergometer test and the Glittre-ADL and ADL simulation tests for the ADLs performance. Results An average 172.51 +/- 25.94 rings were moved in 6 min. The number of rings in 6PBRT was significantly positively correlated with the number of cycles in ADL simulation test (r = 0.553, p < 0.001), peak oxygen consumption in arm ergometer (r = 0.381, p = 0.024) and serum hemoglobin level (r = 0.411, p = 0.011). Conclusion The number of rings moved in the 6PBRT is associated with ADL simulation test performance that reflects upper extremity ADLs. Therefore, the 6PBRT can be used for estimating limitation in upper extremity ADLs as a simple and quick evaluation in patients with GOLD stage II-III COPD.
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- 2020
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23. Physical activity of patients with bronchiectasis compared with healthy counterparts: A cross-sectional study
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Melda Saglam, Deniz Inal-Ince, Hazal Sonbahar-Ulu, Hulya Arikan, Aslihan Cakmak, Selçuk Zt, Ozge Ozalp, Naciye Vardar-Yagli, Lutfi Coplu, Cemile Bozdemir-Ozel, and Ebru Calik-Kutukcu
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Adult ,Male ,Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Adolescent ,Cross-sectional study ,Physical activity ,Walk Test ,030204 cardiovascular system & hematology ,Critical Care and Intensive Care Medicine ,Pulmonary function testing ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Quality of life ,Surveys and Questionnaires ,Humans ,Medicine ,Muscle Strength ,Exercise ,Aged ,Bronchiectasis ,business.industry ,Middle Aged ,Exercise capacity ,Control subjects ,medicine.disease ,Physical activity level ,Cross-Sectional Studies ,Dyspnea ,030228 respiratory system ,Quality of Life ,Physical therapy ,Female ,Sedentary Behavior ,Cardiology and Cardiovascular Medicine ,business - Abstract
A few studies have implied that patients with bronchiectasis have a more inactive lifestyle than healthy counterparts do. The main objective of this study was to compare physical activity (PA) levels subjectively and objectively between patients with bronchiectasis and healthy individuals using an accelerometer and a questionnaire.The study included 41 patients with bronchiectasis aged 18-65 years and 35 healthy age- and sex-matched control subjects. The PA level was assessed objectively using a multisensorial PA monitor, the SenseWear Armband (SWA), and subjectively with the International Physical Activity Questionnaire (IPAQ). All participants performed the incremental shuttle walk test (ISWT) for the assessment of exercise capacity. Pulmonary function, dyspnea, severity of bronchiectasis, respiratory and peripheral muscle strength, and quality of life were assessed.The pulmonary function test parameters, respiratory and peripheral muscle strength, exercise capacity, step count, moderate- and vigorous-intensity PA duration were significantly lower in patients with bronchiectasis than in the healthy control group (p 0.05). Sedentary, moderate, vigorous, and total PA duration measured using the SWA were higher than those obtained using the IPAQ (p 0.05).Patients with bronchiectasis have a reduced PA level compared with healthy counterparts. The IPAQ (based on the subjective estimation of PA) outcomes differed from the SWA outcomes, reinforcing the necessity for a disease-specific PA questionnaire. IPAQ underestimates the physical activity level compared with objective measurements.
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- 2020
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24. Gait and functional balance in non-CF bronchiectasis
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Naciye Vardar-Yagli, Melda Saglam, Merve Firat, Aslihan Cakmak, Deniz Inal-Ince, Ebru Calik Kutukcu, and Lutfi Coplu
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Physical Therapy, Sports Therapy and Rehabilitation - Abstract
The decline in ambulatory activities and negative alterations in gait characteristics may impair balance and increase fall risk in obstructive lung diseases. Few studies have evaluated balance and gait parameters in individuals with bronchiectasis.This study aimed to compare the gait parameters and functional balance in individuals with non-cystic fibrosis (CF) bronchiectasis and healthy subjects.This cross-sectional and retrospective study analyzed data from 22 individuals with non-CF bronchiectasis and 32 healthy controls recorded between July 2019 and July 2020. Functional balance was assessed using the Timed Up and Go (TUG) test. Gait parameters were evaluated using the Biodex Gait Trainer. Step cycle (s), gait speed (m/s), the number of steps per minute, and ambulation index were measured for 6 min.Results The TUG time (s) was significantly longer (p = .019, effect size = 0.66), and gait speed (m/s) (p ˂ 0.001, effect size = 2.47), step cycle (s) (p ˂ 0.001, effect size = 2.23), and ambulation index (p ˂ 0.001, effect size = 2.56) were significantly reduced in individuals with non-CF bronchiectasis compared with healthy controls.Non-CF bronchiectasis is related to unfavorable changes in gait characteristics, such as slower gait speed and the decreased average step cycle. In addition, impairment in functional balance and mobility exists in a small percentage of adults with non-CF bronchiectasis. In comprehensive pulmonary rehabilitation, balance and gait evaluations should be included to prevent falls in adults with non-CF bronchiectasis.
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- 2022
25. Assessment of Exercise Capacity Using Field Walking Tests in Patients with Fontan Procedure: A Case-Control Study
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Haluk Tekerlek, Melda Saglam, Ali Cem Kucukdagli, Hayrettin Hakan Aykan, Naciye Vardar-Yagli, Ebru Calik-Kutukcu, Deniz Inal-Ince, and Tevfik Karagoz
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- 2022
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26. EFFECTS OF LEFT VENTRICULAR MASS INDEX AND LEFT VENTRICULAR GEOMETRY ON 6 MINUTE STEPPER TEST RESULTS IN PATIENTS WITH HYPERTENSION
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Yusuf Ziya Sener, Beyza Nur Durukan, Emine Burcu Ozcan, Ebru Calik Kutukcu, Melda Saglam, Naciye Vardar Yagli, Deniz Inal Ince, and Lale Tokgozoglu
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Physiology ,Internal Medicine ,Cardiology and Cardiovascular Medicine - Published
- 2022
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27. A comparison of arm exercise capacity and activities of daily living between well-controlled asthma patients with and without severe fatigue during daily life
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Gül Karakaya, Aslihan Cakmak, Merve Firat, Hazal Sonbahar-Ulu, Deniz Inal Ince, Cemile Bozdemir-Ozel, Hulya Arikan, Naciye Vardar-Yagli, Haluk Tekerlek, Beyza Nur Karadüz, Melda Saglam, and Ebru Calik-Kutukcu
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medicine.medical_specialty ,Activities of daily living ,Arm exercise ,business.industry ,medicine ,Physical therapy ,medicine.disease ,business ,Asthma - Published
- 2021
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28. Physiological Cost in Daily Life Activities in Lung Cancer
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Hamide Sahin, Melda Saglam, Naciye Vardar-Yaglı, Kübra Kılıc, Ebru Calık-Kutukcu, Deniz Inal-Ince, and Saadettin Kılıckap
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Oncology ,medicine.medical_specialty ,business.industry ,Internal medicine ,Daily life activities ,medicine ,Lung cancer ,medicine.disease ,business - Published
- 2021
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29. A comparison of respiratory muscle endurance, respiratory muscle endurance workload, and quality of life in low and high-fatigue colorectal cancer survivors
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Deniz Inal-Ince, Mehmet Fatih Sanver, Melda Saglam, Ebru Calik-Kutukcu, Naciye Vardar-Yagli, Saadettin Kilickap, and Haluk Tekerlek
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medicine.medical_specialty ,Quality of life ,business.industry ,Colorectal cancer ,Respiratory muscle ,Physical therapy ,Medicine ,Workload ,business ,medicine.disease - Published
- 2021
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30. Exercise capacity, peripheral muscle strength, and balance are related in primary ciliary dyskinesia
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Deniz Inal Ince, Naciye Vardar Yagli, Aslihan Cakmak, Melda Saglam, Hazal Sonbahar Ulu, Ebru Calik Kutukcu, and Hayriye Uğur Özçelik
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medicine.medical_specialty ,Physical medicine and rehabilitation ,business.industry ,Medicine ,Exercise capacity ,business ,medicine.disease ,Primary ciliary dyskinesia ,Peripheral muscle ,Balance (ability) - Published
- 2021
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31. Coronaphobia and physical activity level in patients with non-cystic fibrosis bronchiectasis during COVID-19 pandemic
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Deniz Inal-Ince, Melda Saglam, Naciye Vardar-Yagli, Ebru Calik-Kutukcu, Merve Firat, Aslihan Cakmak, and Lutfi Coplu
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medicine.medical_specialty ,Coronavirus disease 2019 (COVID-19) ,business.industry ,Internal medicine ,Non cystic fibrosis bronchiectasis ,Pandemic ,medicine ,In patient ,business ,Physical activity level - Published
- 2021
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32. Effects of Telerehabilitation on Peripheral Muscle Function in Pediatric Cystic Fibrosis Patients During Covid-19 Pandemic
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Ugur Ozcelik, Ebru Yalçin, Beste Ozsezen, Deniz Inal-Ince, Nural Kiper, Kübra Kılıç, Dilber Ademhan-Tural, Birce Sunman, Deniz Dogru, Ebru Calik-Kutukcu, Naciye Vardar-Yagli, Nagehan Emiralioglu, and Melda Saglam
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medicine.medical_specialty ,Coronavirus disease 2019 (COVID-19) ,business.industry ,Internal medicine ,Telerehabilitation ,Pandemic ,Medicine ,business ,medicine.disease ,Cystic fibrosis ,Peripheral muscle - Published
- 2021
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33. Responses to Two Different High-Intensity Interval Exercise Training Protocols on Pulmonary Function and Respiratory Muscle Strength In Diabetes Mellitus
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Cemile Bozdemir Ozel, Hulya Arikan, Giray Kabakci, Ebru Calik Kutukcu, Beyza Nur Karadüz, Deniz Inal Ince, and Selcuk Dagdelen
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medicine.medical_specialty ,business.industry ,High intensity ,Diabetes mellitus ,Internal medicine ,medicine ,Cardiology ,Respiratory muscle ,Interval (graph theory) ,medicine.disease ,business ,Pulmonary function testing - Published
- 2021
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34. Relationship between functional capacity and activities of daily living, quality of life, psychosocial status and frailty in medical intensive care unit patients
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Selman Kiliç, Ebru Ortaç Ersoy, Deniz Inal Ince, Naciye Vardar Yagli, Melda Saglam, and Arzu Topeli
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Gerontology ,Activities of daily living ,Quality of life (healthcare) ,business.industry ,Medical intensive care unit ,Medicine ,business ,Psychosocial - Published
- 2021
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35. Inflammatory responses to incremental exercise in chronic obstructive pulmonary disease
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Aslihan Cakmak, Samiye Yabanoglu-Ciftci, Ipek Baysal, Deniz Inal-Ince, Elif Kocaaga, Lutfi Coplu, and Emirhan Nemutlu
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medicine.medical_specialty ,business.industry ,Internal medicine ,Cardiology ,medicine ,Pulmonary disease ,business ,Incremental exercise - Published
- 2021
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36. Energy expenditure and glucose-lowering effect of different exercise modalities in diabetes mellitus
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Cemile Bozdemir-Ozel, Hülya Arikan, Ebru Çalik-Kutukcu, Beyza Nur Karaduz, Deniz Inal-Ince, Giray Kabakci, and Selçuk Dagdelen
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Male ,Cross-Sectional Studies ,Glucose ,Diabetes Mellitus, Type 2 ,Exercise Test ,Humans ,Physical Therapy, Sports Therapy and Rehabilitation ,Female ,Middle Aged ,Energy Metabolism ,Hypoglycemia - Abstract
Hypoglycaemia is a serious complication of exercise in patients with type 2 diabetes mellitus (T2DM). The aim of this study was to test energy expenditure and the degree of the glucose-lowering effect of different exercise modalities.Cross-sectional study PARTICIPANTS: This study included 44 patients {35 women and nine men, mean age 51 [standard deviation (SD) 5] years} with T2DM [mean HbA1c 7% (SD 1%)].Standardised exercise tests for walking, running and cycling were performed using the 6-minute walk test (6MWT), incremental shuttle walk test (ISWT), and symptom-limited maximal cycle exercise test, respectively. Energy expenditure was assessed with a multisensory accelerometer. Change in capillary glucose levels (∆glucose) was measured before and after each exercise modality.∆Glucose was lower in the 6MWT {median 14 [interquartile range (IQR) 22] mg/dl} than in the ISWT [median 18 (IQR 23) mg/dl; median difference 7 mg/dl, 95% confidence interval (CI) of the difference 3-11] and the cycle test [median 18 (IQR 24) mg/dl; median difference 7 mg/dl, 95% CI 0-16]. Energy expenditure was lower during the 6MWT [median 41 (IQR 18) Kcal] compared with the ISWT [median 51 (IQR 23) Kcal; median difference 11 Kcal, 95% CI 6-16] and the cycle test [median 44 (IQR 25) Kcal; median difference 6 Kcal, 95% CI 0-13].Energy expenditure and corresponding glucose-lowering effect during exercise in patients with T2DM can be predicted from the results of an exercise test. The type of exercise is related to the risk of hypoglycaemia. Walking is associated with the lowest energy expenditure and risk of hypoglycaemia, while cycling and running/jogging cause higher energy expenditure and greater reductions in glucose in patients with T2DM. CONTRIBUTION OF THE PAPER.
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- 2021
37. Physical fitness and activities of daily living in primary ciliary dyskinesia: A retrospective study
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İlker Yatar, Hazal Sonbahar-Ulu, Nagehan Emiralioglu, Cemile Bozdemir-Ozel, Ebru Calik-Kutukcu, Deniz Inal-Ince, Naciye Vardar-Yagli, Melda Saglam, Haluk Tekerlek, Hülya Arikan, Aslihan Cakmak, and Ugur Ozcelik
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medicine.medical_specialty ,Activities of daily living ,Respiratory tract infections ,business.industry ,medicine.medical_treatment ,Physical fitness ,medicine.disease ,Pulmonary function testing ,law.invention ,law ,Physical Fitness ,Internal medicine ,Pediatrics, Perinatology and Child Health ,Activities of Daily Living ,otorhinolaryngologic diseases ,Respiratory muscle ,Exercise Test ,Medicine ,Humans ,Pulmonary rehabilitation ,business ,Spirometer ,Primary ciliary dyskinesia ,Ciliary Motility Disorders ,Retrospective Studies - Abstract
BACKGROUND Primary ciliary dyskinesia (PCD) is a rare, hereditary, autosomal recessive disorder characterized by recurrent upper and lower respiratory tract infections. This study aimed to retrospectively compare pulmonary function, respiratory muscle strength, exercise capacity, physical fitness, and activities of daily living (ADLs) between patients with PCD and healthy controls. METHODS Data from 20 patients with PCD and 20 matched, healthy counterparts recorded between July 2015 and January 2017 were analyzed. The data evaluated and recorded included pulmonary function (using a portable spirometer), respiratory muscle strength (using a mouth pressure device), exercise capacity (using the incremental shuttle walk test [ISWT]), physical fitness (using the Munich Fitness Test [MFT]), and ADLs (using the Glittre ADL test). RESULTS Pulmonary function, respiratory muscle strength, ISWT scores (all parameters), and total MFT scores were lower in the PCD group relative to controls (P < 0.05). The duration to complete the Glittre ADL test was higher in PCD patients than in healthy subjects (P < 0.05). CONCLUSION Pulmonary function, respiratory muscle strength, exercise capacity, physical fitness, and ADL were affected by PCD. Thus, pulmonary rehabilitation regimens should be tailored according to these impacts.
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- 2021
38. Increased pain sensitivity, postural abnormalities, and functional balance impairment in obstructive lung disease compared to healthy subjects
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Hulya Arikan, Naciye Vardar-Yagli, Deniz Inal-Ince, Melda Saglam, Ebru Calik-Kutukcu, and Lutfi Coplu
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Adult ,Male ,Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Adolescent ,Functional balance ,Posture ,Pain ,Comorbidity ,Timed Up and Go test ,030204 cardiovascular system & hematology ,Critical Care and Intensive Care Medicine ,Pulmonary Disease, Chronic Obstructive ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,medicine ,Humans ,Postural Balance ,Aged ,COPD ,Bronchiectasis ,Lung ,business.industry ,Healthy subjects ,Middle Aged ,medicine.disease ,Obstructive lung disease ,respiratory tract diseases ,medicine.anatomical_structure ,030228 respiratory system ,Female ,Cardiology and Cardiovascular Medicine ,business - Abstract
Recent reports have identified pain as a comorbidity in obstructive lung diseases, but data regarding pain in certain obstructive lung diseases such as COPD and bronchiectasis vs. healthy controls and differences in pain between these chronic lung diseases are limited.The primary aim of this study was to compare pain sensitivity, postural abnormalities, and functional balance in patients with COPD/bronchiectasis vs. healthy controls. The secondary aim was to evaluate differences in these parameters between two different lung diseases (COPD and bronchiectasis).Twenty-nine patients with moderate to severe COPD/bronchiectasis and 31 healthy age/gender-matched individuals participated in the study. Pain sensitivity was assessed with an algometer. Postural abnormalities were analyzed from the lateral and posterior view. Functional balance was evaluated using the Timed Up and Go test (TUG).Significantly more patients reported pain compared to the healthy controls (89.7% vs. 19.4%, respectively) (p 0.05). The pressure pain thresholds of the trapezius and deltoid muscles and pain tolerance of the pectoralis major muscle were significantly lower in patients compared to healthy subjects (p 0.05). Total and posterior posture scores and TUG time were significantly higher in patients compared to the control group (p 0.05).This study showed that pain perception, severity, and sensitivity are increased in patients with COPD or bronchiectasis compared to the healthy population. These patients also have more severe postural abnormalities and functional balance impairment than the healthy population.
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- 2019
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39. Aerobic exercise training in Kartagener’s syndrome
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Naciye Vardar-Yagli, Ugur Ozcelik, Ebru Calik-Kutukcu, Deniz Inal-Ince, Melda Saglam, Aslihan Cakmak, E. Yalcin, Cemile Bozdemir-Ozel, Haluk Tekerlek, Hulya Arikan, Hazal Sonbahar-Ulu, and Fizyoterapi ve Rehabilitasyon
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030506 rehabilitation ,medicine.medical_specialty ,medicine.medical_treatment ,Physical Therapy, Sports Therapy and Rehabilitation ,Chest physiotherapy ,Pulmonary function testing ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,Randomized controlled trial ,law ,Heart rate ,Medicine ,Aerobic exercise ,Orthopedics and Sports Medicine ,Pulmonary rehabilitation ,Exercise ,Respiratory disease ,Bronchiectasis ,business.industry ,Standard treatment ,030229 sport sciences ,medicine.disease ,Physical therapy ,Original Article ,0305 other medical science ,business - Abstract
Kartagener’s syndrome is a rare, autosomal recessive inherited disease, which is characterized by a triad of chronic sinusitis, bronchiectasis, and situs inversus. In this report, we aimed to represent the effect of aerobic exercise training in addition to chest physiotherapy in an outpatient with Kartagener’s syndrome. An 18-year-old female diagnosed with Kartagener’s syndrome applied with the complaints of productive cough and dyspnea with exertion and attended pulmonary rehabilitation program comprising exercise training in addition to standard treatment. Aerobic exercise training was performed three times weekly at 80% of the peak heart rate, for 8 weeks as supervised sessions. Respiratory physiotherapy and postural exercises were taught to the patient to be performed at home each day of the week. Before and after pulmonary rehabilitation program, incremental shuttle walk test (ISWT) was performed; dyspnea and fatigue were assessed using Borg Scale. Pulmonary function test was evaluated using spirometer. The patient wore activity monitor for 7 consecutive days before and after training. After pulmonary rehabilitation program, 90-m increase in ISWT was observed. We recommend exercise training in patients with Kartagener’s syndrome to increase exercise capacity. Further randomized control trial is needed to clarify the effects.
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- 2019
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40. Validity and reliability of 6-minute pegboard and ring test in patients with asthma
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Ebru Calik-Kutukcu, Gül Karakaya, Deniz Inal-Ince, Saltuk Bugra Kaya, Melda Saglam, Cemile Bozdemir-Ozel, Haluk Tekerlek, Merve Firat, Hülya Arikan, Aslihan Cakmak, Beyza Nur Karadüz, Hazal Sonbahar-Ulu, and Naciye Vardar-Yagli
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Pulmonary and Respiratory Medicine ,Adult ,Male ,Allergy ,medicine.medical_specialty ,Activities of daily living ,Validity ,Pulmonary disease ,behavioral disciplines and activities ,03 medical and health sciences ,0302 clinical medicine ,Surveys and Questionnaires ,Activities of Daily Living ,medicine ,Immunology and Allergy ,Humans ,In patient ,030212 general & internal medicine ,Asthma ,Ring (mathematics) ,Hand Strength ,business.industry ,Reproducibility of Results ,medicine.disease ,Test (assessment) ,030228 respiratory system ,Pediatrics, Perinatology and Child Health ,Physical therapy ,Exercise Test ,Quality of Life ,Female ,business - Abstract
The 6-minute pegboard and ring test (6PBRT) is a test of upper-extremity functional capacity designed for and validated in chronic obstructive pulmonary disease. The aim of this study was to evaluate the validity and reliability of the 6PBRT in asthma patients.Thirty-four adults (30 women, 4 men) with well-controlled asthma were included. Unsupported upper-extremity exercise capacity was assessed using 6PBRT, maximal arm exercise capacity using an arm ergometer, handgrip strength using a hand dynamometer, activities of daily living with the London Chest Activities of Daily Living Scale (LCADL), Milliken ADL scale (MAS) and health-related quality of life using the Asthma Quality of Life Questionnaire (AQLQ) and Health Assessment Questionnaire Disability Index (HAQ-DI).The 6PBRT showed moderate to excellent test-retest reliability with an intraclass correlation coefficient (ICC) value of 0.872 [95% confidence interval (CI) 0.702-0.941]. The 6PBRT was reproducible according to Bland-Altman analysis, with upper and lower limits of agreement of 53.51 and -25.08 rings moved, respectively. The 6PBRT score was significantly correlated with maximum workload (The 6PBRT can be used as a valid and reliable test to evaluate functional arm exercise capacity in patients with well-controlled asthma.
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- 2021
41. Reliability and validity of the Turkish version of Post-COVID-19 Functional Status Scale
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Deniz Inal Ince, Aslihan Cakmak, Oğuz Abdullah Uyaroğlu, Lale Ozisik, Esra Kinaci, Gulay Sain Guven, Melda Saglam, Nursel Çalık Başaran, Naciye Vardar Yagli, and Ebru Calik Kutukcu
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Adult ,Male ,medicine.medical_specialty ,Activities of daily living ,Scale (ratio) ,Turkey ,Turkish ,Intraclass correlation ,functional status ,Article ,reliabilities ,Young Adult ,Cronbach's alpha ,Medicine ,Humans ,Reliability (statistics) ,business.industry ,Construct validity ,COVID-19 ,Reproducibility of Results ,Covid 19 ,General Medicine ,test-retest ,Middle Aged ,dyspnea ,SARS-CoV-2 infection ,language.human_language ,Cross-Sectional Studies ,language ,Physical therapy ,Functional status ,Female ,business - Abstract
BACKGROUND/AIMS: The Post-COVID-19 Functional Status Scale (PCFS) has recently been developed for functional outcomes of COVID-19 upon discharge and in long term. The purpose of this study was to investigate the reliability and validity properties of the Turkish version of the PCFS in Turkish post-COVID-19 patients with hospitalized and non-hospitalized during infection. MATERIALS AND METHODS: One hundred participants with post-COVID-19 were included in this cross-sectional study. Test-retest reliability of the Turkish version of PCFS assessed by intraclass correlation coefficient (ICC) and Cronbach?s alpha was calculated for internal consistency. For construct validity, correlation coefficients between the Turkish version of PCFS developed by translation-back translation method and Modified Medical Research Council dyspnea scale (MMRC), London Chest Activities of Daily Living Scale (LCADL), Barthel Index (BI) were analyzed. RESULTS: For test-retest reliability analysis, ICC ranged between 0.734 and 0.880. The total ICC score was 0.821, indicating excellent reliability. The Cronbach?s alpha value of the PCFS test and retest scores were recorded as 0.821 indicating that the scale is quite reliable. The PCFS score was moderately correlated with the MMRC score (r=0.534, p
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- 2021
42. Daily living activities, exercise capacity, cognition, and balance in COPD patients with and without frailty
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Deniz Inal-Ince, Sezen Kagiali, Ebru Calik-Kutukcu, Hülya Arikan, Melda Saglam, Aslihan Cakmak, Lutfi Coplu, Naciye Vardar-Yagli, Cemile Bozdemir-Ozel, Haluk Tekerlek, and Hazal Sonbahar-Ulu
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medicine.medical_specialty ,Activities of daily living ,Copd patients ,medicine.medical_treatment ,030204 cardiovascular system & hematology ,03 medical and health sciences ,Pulmonary Disease, Chronic Obstructive ,0302 clinical medicine ,Cognition ,Quality of life ,Activities of Daily Living ,medicine ,Humans ,Pulmonary rehabilitation ,030212 general & internal medicine ,Balance (ability) ,COPD ,Rehabilitation ,Exercise Tolerance ,Frailty ,Hand Strength ,business.industry ,General Medicine ,medicine.disease ,respiratory tract diseases ,Dyspnea ,Physical therapy ,Exercise Test ,Quality of Life ,business ,human activities - Abstract
Information on the interaction between frailty and chronic obstructive pulmonary disease (COPD) is limited.This study aimed to compare activities of daily living (ADL), exercise capacity, balance, and cognition in COPD patients with and without frailty.Twenty frail and 28 non-frail COPD patients aged 55 years and over were included. Frailty was determined according to Fried et al. Dyspnea was evaluated using the modified Medical Research Council (mMRC) dyspnea scale. Respiratory and peripheral muscle strength were measured. Functional capacity was assessed using a 6-min walk test (6MWT); ADL performance was evaluated using the Glittre ADL test. The balance was evaluated using the functional reach test (FRT). Cognitive function was assessed using the Montreal Cognitive Evaluation (MoCA) Test. Quality of life was measured using the COPD Assessment Test (CAT).The mMRC and CAT scores were higher in the frail patients as compared with the non-frail patients (p0.05). The maximal inspiratory pressure, handgrip strength, 6MWT distance, and FRT score were lower in the frail patients as compared with the non-frail patients (p0.05). The duration for the Glittre ADL test was longer in the frail patients than the non-frail patients (p0.05). There was no significant difference between MoCA scores between groups (p0.05).Frail COPD patients have increased dyspnea perception, impaired muscle strength, and functional capacity, ADL performance, balance, and quality of life. Whether pulmonary rehabilitation programs for patients with frail COPD need to be adapted with new rehabilitation strategies, including components of frailty, needs further investigation.
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- 2021
43. Multi-dimensional evaluation of daily living activities in lung cancer
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Saadettin Kilickap, Deniz Inal Ince, Kübra Kılıç, Melda Saglam, Hamide Sahin, Naciye Vardar Yagli, and Ebru Calik Kutukcu
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Oncology ,medicine.medical_specialty ,Activities of daily living ,business.industry ,Internal medicine ,medicine ,Multi dimensional ,business ,Lung cancer ,medicine.disease - Published
- 2020
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44. Evaluation of functional exercise capacity using two-field test in lung cancer patients
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Saadettin Kilickap, Deniz Inal Ince, Naciye Vardar Yagli, Kübra Kılıç, Ebru Calik Kutukcu, and Melda Saglam
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medicine.medical_specialty ,Field (physics) ,business.industry ,Functional exercise ,Physical therapy ,Medicine ,business ,Lung cancer ,medicine.disease ,Test (assessment) - Published
- 2020
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45. Physical activity, functional capacity, and anaerobic power in cystic fibrosis with and without impaired glucose tolerance
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Deniz Inal-Ince, Nagehan Emiralioglu, Ayfer Alikasifoglu, Ebru Calik-Kutukcu, Deniz Dogru, Cemile Bozdemir-Ozel, Naciye Vardar-Yagli, Elif Kocaaga, Dilber Ademhan-Tural, and Melda Saglam
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Impaired glucose tolerance ,medicine.medical_specialty ,Endocrinology ,business.industry ,Internal medicine ,Physical activity ,Medicine ,business ,medicine.disease ,Cystic fibrosis ,Anaerobic exercise - Published
- 2020
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46. The Association Between BODEx Index and Activities of Daily Living, Occupational Performance, Psychosocial Status and Health Related Quality of Life in Patients with COPD
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Hülya Arikan, Sema Savci, Çiğdem Öksüz, Deniz Inal-Ince, Lutfi Coplu, Beyza Nur Karadüz, Ebru Calik-Kutukcu, Melda Saglam, Tülin Düger, and Naciye Vardar-Yagli
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Health related quality of life ,COPD ,medicine.medical_specialty ,Index (economics) ,Activities of daily living ,business.industry ,medicine.medical_treatment ,medicine.disease ,medicine ,Physical therapy ,Pulmonary rehabilitation ,In patient ,business ,Psychosocial ,Body mass index - Abstract
Introduction and Background: BODEx index which is a multidimensional disease severity index and simplified version of BODE in chronic obstructive pulmonary disease (COPD) patients. There is limited use of BODEx index in Europe but it can be practical for daily living activities (ADL) status in COPD. Aim and Objectives: The aim was to evaluate the association between BODEx index and ADL, occupational performance, psychosocial status and health related quality of life (HRQoL) in patients with COPD. Methods: Twenty-seven patients with COPD (mean age: 58.6 ± 9.6 years, mean %FEV1=50.6±13.7) were included in the study. BODEx index was calculated according to Body mass index, airflow Obstruction, Dyspnea with MMRC scale and Exacerbations. ADL was evaluated with London Chest ADL Scale (LCADL). Occupational performance was assessed by Canadian Occupational Performance Measurement (COPM). Psychosocial status was determined with Hospital Anxiety amd Depression Scale (HADS) and HRQoL was assessed with COPD Assesment Test (CAT). Results: Mean BODEx score of patients was 3.6±1.6. The BODEx score was significantly correlated with COPM-satisfaction score (r=-0.474, p=0.014), LCADL-leisure time score (r=0.473, p=0.013), HADS-anxiety score (r=0.420, p=0.029) and CAT score (r=0.430, p=0.028). Conclusions: As the multidimensional disease severity increase, daily living activities, satisfaction from occupational performance, health related quality of life and psychosocial status deteriorate in COPD. BODEx index can be a practical metod for understanding functional impairment of patients in pulmonary rehabilitation.
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- 2020
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47. Relationship of Respiratory Muscle Endurance Workload with Maximal Oxygen Consumption and Fatigue in Individuals Surviving Colorectal Cancer
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Deniz Inal Ince, Haluk Tekerlek, Saadettin Kilickap, Melda Saglam, Mehmet Fatih Sanver, Naciye Vardar Yagli, and Ebru Calik Kutukcu
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medicine.medical_specialty ,business.industry ,Colorectal cancer ,Internal medicine ,Cardiology ,medicine ,Respiratory muscle ,VO2 max ,Workload ,business ,medicine.disease - Published
- 2020
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48. Dynamic Balance, Exercise Capacity and Muscle Oxygenation in Children with Non Cystic Fibrosis Bronchiectasis
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Deniz Dogru Ersoz, Deniz Inal Ince, Naciye Vardar Yagli, Melda Saglam, Jan Dik, Haluk Tekerlek, and Ebru Calik Kutukcu
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medicine.medical_specialty ,Bronchiectasis ,business.industry ,Non cystic fibrosis bronchiectasis ,Exercise capacity ,medicine.disease ,Muscle oxygenation ,Fibrosis ,Internal medicine ,Postural stability ,Cardiology ,medicine ,Dynamic balance ,business ,Balance (ability) - Abstract
Aim: Balance, coordination, and postural stability have gained the importance as other extrapulmonary involvements, in addition to the pulmonary system and other body systems involvements in patients with non-cystic fibrosis (CF) bronchiectasis. In this study, it was aimed to compare dynamic balance, exercise capacity, and muscle oxygenation change during exercise in children with bronchiectasis and healthy children. Methods: Fifteen children with non-CF bronchiectasis (12.60±2.84 yrs, 7 females, 8 males) and 15 healthy children (11.80±3.25 yrs, 7 females, 8 males) were included. Exercise capacity using incremental shuttle walk test (ISWT), dynamic balance using functional reach test (FRT), and muscle oxygenation change during exercise (ΔSmO2) using wearable lactate measuring device were measured. Results: Demographic characteristics were similar between non-CF bronchiechtasis and control groups (p>0.05). The ISWT distances were shorter (p Discussion: Exercise capacity, oxygen consumption and muscle oxygenation level are impaired whereas dynamic balance is preserved in non-CF bronchiectasis. It’ s important to monitor muscle oxygenation level during exercise testing in these patients.
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- 2020
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49. Lower limb function in pediatric interstitial lung disease
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Kübra Kılıç, Beste Ozsezen, Deniz Dogru, Deniz Inal-Ince, Melda Saglam, Naciye Vardar-Yagli, Nagehan Emiralioglu, and Nural Kiper
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medicine.medical_specialty ,business.industry ,Internal medicine ,medicine ,Cardiology ,Interstitial lung disease ,medicine.disease ,business ,Lower limb - Published
- 2020
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50. Predictors of Exercise Capacity in Patients with OSAS
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Melike Yuceege, Naciye Vardar-Yagli, Sadik Ardic, Ebru Calik-Kutukcu, Melda Saglam, Hulya Arikan, Hakan Çalışkan, Sema Savci, Nurel Ertürk, Hikmet Firat, and Deniz Inal-Ince
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medicine.medical_specialty ,business.industry ,Physical therapy ,medicine ,In patient ,Exercise capacity ,business - Published
- 2020
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