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Introduction:Our aim was to compare NT-proBNP levels and cardiac functions after irontherapy in children with congenital cyanotic heart disease who had irondeficiency anemia.Materialsand Methods: We included 40 children withpre-established cyanotic congenital heart disease and accompanying iron deficiencyanemia, between the age of 6 months and 17 years, who were admitted to theoutpatient clinic of Çukurova University Faculty of Medicine, Department ofPediatric Cardiology between September 2015 and March 2016. We recordeddemographic data and performed following investigations: complete blood count,peripheral blood smear, reticulocyte count, measurement of serum iron levels,total iron-binding capacity, ferritin levels, transferrin saturation andNT-proBNP levels, and echocardiographic examination.Results:There was a statistically significant increase in following laboratoryparameters after iron therapy: hemoglobin, hematocrit, MCV, MCHC, serum ironand ferritin, transferrin saturation and oxygen saturation. During thefollow-up period, RDW and NT-proBNP levels were significantly decreased. Inleft ventricular tissue doppler; there was a significant difference in MPImeasurements before and after treatment. There was no significant difference inother echocardiography findings.Conclusion:Iron therapy has improved cardiac functions in children with cyanoticcongenital heart disease, and NT-proBNP levels can be used to evaluate theefficacy of treatment in the follow-up period., Amaç: Demireksikliği anemisi olan doğumsal siyanotik kalp hastalıklı çocuklarda demirtedavisi sonrası NT-proBNP düzeyleri ve kardiyak fonksiyonlarınkarşılaştırılmasıdır.Gereçve Yöntem:Eylül 2015 - Mart 2016 tarihleri arasındaÇukurova Üniversitesi Tıp Fakültesi Çocuk Kardiyoloji Bilim Dalı polikliniğinebaşvuran, siyanotik doğuştan kalp hastalığı tanılı, demir eksikliği anemisisaptanan altı ay ile 17 yaşları arasındaki 40 çocuk hasta çalışmaya alınmıştır.Çeşitli sebeplerden dolayı 26 hasta ile sonuçlar değerlendirilmiştir.Hastaların ilk geliş ve üçüncü ay kontrollerinde; demografik verileri, tam kansayımı, periferik yayma, retikülosit, serum demir, total demir bağlamakapasitesi, ferritin düzeyleri, transferrin satürasyonlarıu, NT-proBNPdüzeyleri ve Eko bulguları değerlendirilmiştir.Bulgular: Hastalarındemir tedavisi öncesi ve sonrası laboratuvar değerlerinde; hemoglobin,hematokrit, MCV, MCHC, demir, ferritin, transferin saturasyonu, oksijen saturasyonudeğerleri tedavi sonrası istatistiksel olarak anlamlı derece artmıştır. RDW veNT-proBNP düzeyleri yüksekliği kontrol sonuçlarında anlamlı olarak düşmüştür.Sol ventrikül doku dopplerinde; MPİ ölçümlerinde tedavi öncesi ve sonrasındaanlamlı farklılık saptanmıştır. Diğer EKO bulgularında anlamlı farklılıksaptanmamıştır.Sonuç: Demirtedavisi sonrası siyanotik doğuştan kalp hastalıklı çocuklarda kardiyakfonksiyonlarda iyileşme saptanmış olup NT-proBNP takipte, tedavinindeğerlendirilmesinde kullanılabilir. more...

Aim: Over the past 2 decades, transcatheter occlusion of patent ductus arteriosus (PDA) with coils and the duct occluders evolved to be the procedure of choice. A new device, the Occlutech PDA1 occluder (ODO) device has been designed. Herein, we aimed to evaluate the characteristics and short-term results of patients who underwent transcatheter closure of PDA using the ODO. more...

WOS: 000384919800011 PubMed ID: 27090770 Aim: Over the past 2 decades, transcatheter occlusion of patent ductus arteriosus (PDA) with coils and the duct occluders evolved to be the procedure of choice. A new device, the Occlutech PDA1 occluder (ODO) device has been designed. Herein, we aimed to evaluate the characteristics and short-term results of patients who underwent transcatheter closure of PDA using the ODO. Methods: We reviewed the clinical records of 60 patients from different centers in Turkey between December 2013 and January 2016. The medical records were reviewed for demographic characteristics and echocardiographic findings. Device size was selected on the narrowest diameter of PDA. Results: The median patient age was 2.5 years (6 months-35 years), and median PDA diameter was 2.5mm (1.2-11 mm). Fifty-eight of 60 patients (96.6%) had successful ODO implantation. The occlusion rates were 37/58 (63.7%) at the end of the procedure, 51/58 (87.9%) at 24-48 hours post-procedure, and 57/58 (98.2%) on echocardiography at a median follow-up of 7.6 months. Conclusion: Our results indicate that transcatheter closure of PDA using the ODO is effective. Larger studies and longer follow-up are required to assess whether its shape and longer length make it superior to other duct occluders in large, tubular, or window-type ducts. more...

Amaç: Bu çalışmada Scimitar sendromu tanısı konulmuş hastalar değerlendirildi.Ça­lış­ma­pla­nı:­Çalışmaya Ocak 2003 - Aralık 2011 tarihleri arasında kliniğimizde Scimitar sendromu tanısı konulmuş ortalama ağırlıkları 16.7±21.8 kg olan, 12 hasta (8 kız, 4 erkek; ort. yaş 4.0±4.8 yıl; dağılım 1 ay - 16 yıl), alındı. Hastaların klinik bulguları, fizik muayene, telekardiyografi, ekokardiyografi, kalp kateterizasyonu ve cerahi bulguları ve izlem verileri geriye dönük olarak gözden geçirildi.Bul gu lar: On iki hastadan beşi (%42) infantil tip ve yedisi (%58) çocuk/erişkin tip Scimitar sendromu olarak değerlendirildi. İnfantil tipteki hastaların tümünde taşipne ve kalp yetersizliği bulguları varken, çocuk/erişkin tipteki hastaların birinde tekrarlayan alt solunum yolu enfeksiyonu öyküsü vardı. Ek kardiyak defektler hastaların yedisinde atriyal septal defekt, birinde aort koarktasyonu, ikisinde patent duktus arteriyozus ve birinde ventriküler septal defekt ile pulmoner atrezi idi. Bir hastada iki taraflı Scimitar sendromu vardı. İnfantil Scimitar sendromlu hastaların tümü şiddetli pulmoner hipertansiyonlu iken, çocuk/erişkin tipteki hastalardan biri hafif pulmoner hipertansiyonlu idi. Aortopulmoner kollateral arter saptanan dokuz hastadan altısında arter transkateter yolla kapatıldı. On hastaya (%83) cerrahi girişim uygulandı. İnfantil Scimitar sendromlu bir hasta ameliyat sonrası erken dönemde, ameliyat edilmeyen iki taraflı Scimitar sendromlu diğer bir hasta ise takipte akciğer enfeksiyonu nedeniyle kaybedildi.So nuç: Scimitar sendromu farklı klinik tablolarla seyredebilen nadir bir sendromdur. Çocuk/erişkin tip hastalığı olan hastalar sıklıkla asemptomatiktir; ancak tekrarlayan akciğer enfeksiyonları da izlenebilir. Aortopulmoner kollateral oklüzyon semptomatik iyileşme sağlayabilse de özellikle Scimitar veni tıkanmış ve ilave kardiyak anomalisi bulunan hastalarda cerrahi gerekir. Background: This study aims to evaluate patients diagnosed with Scimitar syndrome. Methods: Twelve patients (8 girls, 4 boys; mean age: 4.0±4.8 years; range 1 month to 16 years) with a mean weight of 16.7±21.8 kg who were diagnosed with Scimitar syndrome in our clinic between January 2003 and December 2011 were included. Clinical findings of the patients, physical examination, telecardiography, echocardiography, cardiac catheterization, and surgical findings and follow-up data were retrospectively reviewed. Results: Of 12 patients, five (42%) were considered with infantile type and seven (58%) with child/adult type Scimitar syndrome. All patients of infantile type presented with tachypnea and cardiac failure findings, while one patient with child/adult type had a history of recurrent lower respiratory tract infection. Additional cardiac defects were atrial septal defect in seven, coarctation in one, patent ductus arteriosus in two, and ventricular septal defect with pulmonary atresia in one patient. Bilateral Scimitary syndrome was present in one patient. All infantile type patients had severe pulmonary hypertension, while only one of the child/adult type patients had mild pulmonary hypertension. Six of nine patients with aortopulmonary collateral artery underwent transcatheter closure of the artery. Surgery was performed in 10 patients (83%). One patient with infantile type in the early postoperative period and another patient with bilateral Scimitar syndrome who was not operated during follow-up died due to pulmonary infection. Conclusion: Scimitar syndrome is a rare syndrome which may present with different clinical presentations. Patients with child/ adult type disease are often asymptomatic, however, may present with recurrent pulmonary infections. Although aortopulmonary collateral occlusion may provide symptomatic relief, surgery is indicated in patients with obstructed Scimitar vein and additional cardiac anomalies, in particular. more...

Background: To investigate the methods of percutaneous transcatheter interventions for combined congenital heart disease and to evaluate its effi cacy in children. Materials and Methods: Thirty cases (ages 3 days-13.5 years, body weight 3-35 kg) that underwent two multiple transcatheter interventions for combined or solitary congenital heart disease were retrospectively analyzed and presented. Results: A total of 61 transcatheter interventions were performed in 30 patients as combined procedures. In 29 patients, two different procedures were combined in the same session, in remaining one patient, combination of three interventions were performed in the same catheter session. Interventions performed in combined procedures were as follows: Coarctation balloon angioplasty in 12 cases, pulmonary balloon valvuloplasty in 10, PDA coil embolization in 10, aortic balloon valvuloplasty in 8, VSD closure in 5, ASD closure in 4, ductal stent implantation in 4, palliative pulmonary balloon valvuloplasty in 3, recanalization and angioplasty of the systemic-pulmonary shunt in 2, balloon atrial septostomy in one, aortic coarctation stent implantation in one, coil embolization of a pulmonary lobar sequestration in one and pulmonary valve perforation plus pulmonary balloon valvuloplasty in one were performed as fi rst or second procedure. There was no mortality or major morbidity in relation to combined procedures. Conclusion: Multiple transcatheter interventions in the same session are feasible, safe and effective with satisfactory good results. Second intervention may be performed as complementary procedure or independently to the fi rst intervention. Key words: Congenital cardiac defects, percutaneous procedures, percutaneous treatment. more...