1. Diaphragmatic paralysis resulting in respiratory failure as a feature of hepatitis E virus-associated neuralgic amyotrophy
- Author
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Shakya Bhattacharjee, Muhammed Ameen Noushad, Demetra Limnatitou, and Azlisham Mohd Nor
- Subjects
Male ,viruses ,Case Report ,Diaphragmatic paralysis ,medicine.disease_cause ,03 medical and health sciences ,0302 clinical medicine ,Hepatitis E virus ,Medicine ,Brachial Plexus Neuritis ,Humans ,Paralysis ,Respiratory function ,Phrenic nerve ,business.industry ,virus diseases ,General Medicine ,Respiratory Paralysis ,Hepatitis E ,Phrenic Nerve ,Lumbosacral plexus ,Respiratory failure ,Anesthesia ,Breathing ,030211 gastroenterology & hepatology ,business ,Brachial plexus ,030217 neurology & neurosurgery - Abstract
Hepatitis E virus (HEV)-associated neuralgic amyotrophy (NA) is often bilateral and severe, involving structures outside the brachial plexus, such as the phrenic nerves or the lumbosacral plexus. We report a case of an HEV-positive man who had presented with brachial neuritis, with significant phrenic nerve involvement, resulting in diaphragmatic paralysis requiring non-invasive ventilation. Prognosis of HEV-associated NA is often unfavourable and recovery is usually incomplete. Identifying HEV-associated NA early could potentially aid in prognostication and management planning, as clinicians and patients would be expectant of its potential features and severity. Respiratory function should be monitored in patients with HEV who suffer from NA, as diaphragmatic paralysis could potentially lead to severe respiration difficulties requiring ventilatory support.
- Published
- 2023