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19 results on '"Demas, William F."'

2. Gender and age make no difference in the re-irradiation of painful bone metastases: A secondary analysis of the NCIC CTG SC.20 randomized trial

Author

Chow, Ronald, Ding, Keyue, Ganesh, Vithusha, Meyer, Ralph M., van der Linden, Yvette M., Roos, Daniel, Hartsell, William F., Hoskin, Peter, Wu, Jackson S.Y., Nabid, Abdenour, van Acht, Manouk, Wanders, Rinus, Babington, Scott, Demas, William F., Wilson, Carolyn F., Wong, Rebecca K.S., Brundage, Michael, Zhu, Liting, and Chow, Edward

Published
2018
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5. Revisiting classification of pain from bone metastases as mild, moderate, or severe based on correlation with function and quality of life

Author

Chow, Edward, Ding, Keyue, Parulekar, Wendy R., Wong, Rebecca K. S., van der Linden, Yvette M., Roos, Daniel, Hartsell, William F., Hoskin, Peter, Wu, Jackson S. Y., Nabid, Abdenour, Ong, Francisca, van Tienhoven, Geertjan, Babington, Scott, Demas, William F., Wilson, Carolyn F., Brundage, Michael, Zhu, Liting, and Meyer, Ralph M.

Published
2016
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11. Minimal clinically important differences in the EORTC QLQ-C30 and brief pain inventory in patients undergoing re-irradiation for painful bone metastases

Author

Raman, Srinivas, primary, Ding, Keyue, additional, Chow, Edward, additional, Meyer, Ralph M., additional, van der Linden, Yvette M., additional, Roos, Daniel, additional, Hartsell, William F., additional, Hoskin, Peter, additional, Wu, Jackson S. Y., additional, Nabid, Abdenour, additional, Haas, Rick, additional, Wiggenraad, Ruud, additional, Babington, Scott, additional, Demas, William F., additional, Wilson, Carolyn F., additional, Wong, Rebecca K. S., additional, Zhu, Liting, additional, and Brundage, Michael, additional

Published
2017
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12. Revisiting classification of pain from bone metastases as mild, moderate, or severe based on correlation with function and quality of life

Author

Chow, Edward, primary, Ding, Keyue, additional, Parulekar, Wendy R., additional, Wong, Rebecca K. S., additional, van der Linden, Yvette M., additional, Roos, Daniel, additional, Hartsell, William F., additional, Hoskin, Peter, additional, Wu, Jackson S. Y., additional, Nabid, Abdenour, additional, Ong, Francisca, additional, van Tienhoven, Geertjan, additional, Babington, Scott, additional, Demas, William F., additional, Wilson, Carolyn F., additional, Brundage, Michael, additional, Zhu, Liting, additional, and Meyer, Ralph M., additional

Published
2015
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13. Impact of Reirradiation of Painful Osseous Metastases on Quality of Life and Function: A Secondary Analysis of the NCIC CTG SC.20 Randomized Trial

Author

Chow, Edward, primary, Meyer, Ralph M., additional, Chen, Bingshu E., additional, van der Linden, Yvette M., additional, Roos, Daniel, additional, Hartsell, William F., additional, Hoskin, Peter, additional, Wu, Jackson S.Y., additional, Nabid, Abdenour, additional, Tissing-Tan, Caroline J.A., additional, Oei, Bing, additional, Babington, Scott, additional, Demas, William F., additional, Wilson, Carolyn F., additional, Wong, Rebecca K.S., additional, and Brundage, Michael, additional

Published
2014
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14. Single‐fraction radiotherapy versus multifraction radiotherapy for palliation of painful vertebral bone metastases—Equivalent efficacy, less toxicity, more convenient

Author

Howell, David D., primary, James, Jennifer L., additional, Hartsell, William F., additional, Suntharalingam, Mohan, additional, Machtay, Mitchell, additional, Suh, John H., additional, Demas, William F., additional, Sandler, Howard M., additional, Kachnic, Lisa A., additional, and Berk, Lawrence B., additional

Published
2012
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15. Abstract 736: RTOG 0320:A phase III trial comparing whole brain radiation therapy (WBRT) and stereotactic radiosurgery (SRS) alone versus WBRT with temozolomide (TMZ) or erlotinib for non-small cell lung cancer (NSCLC) and 1-3 brain metastases

Author

Sperduto, Paul W., primary, Wang, Meihua, additional, Robins, H. Ian, additional, Schell, Michael C., additional, Werner-Wasik, Maria, additional, Komaki, Ritsuko U., additional, Souhami, Luis, additional, Buyyounouski@fccc.edu, Mark K., additional, Khuntia, Deepak, additional, Demas, William F., additional, Shah, Sunjay A., additional, Nedzi, Lucien A., additional, Perry, G A., additional, Suh, John H., additional, and Mehta, Minesh P., additional

Published
2012
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19. Single-fraction radiotherapy versus multifraction radiotherapy for palliation of painful vertebral bone metastases-equivalent efficacy, less toxicity, more convenient: a subset analysis of Radiation Therapy Oncology Group trial 97-14.

Author

Howell DD, James JL, Hartsell WF, Suntharalingam M, Machtay M, Suh JH, Demas WF, Sandler HM, Kachnic LA, Berk LB, Howell, David D, James, Jennifer L, Hartsell, William F, Suntharalingam, Mohan, Machtay, Mitchell, Suh, John H, Demas, William F, Sandler, Howard M, Kachnic, Lisa A, and Berk, Lawrence B

Abstract

Background: The Radiation Therapy Oncology Group (RTOG) trial 97-14 revealed no difference between radiation delivered for painful bone metastases at a dose of 8 gray (Gy) in 1 fraction (single-fraction radiotherapy [SFRT]) and 30 Gy in 10 fractions (multifraction radiotherapy [MFRT]) in pain relief or narcotic use 3 months after randomization. SFRT for painful vertebral bone metastases (PVBM) has not been well accepted, possibly because of concerns about efficacy and toxicity. In the current study, the authors evaluated the subset of patients that was treated specifically for patients with PVBM.Methods: PVBM included the cervical, thoracic, and/or lumbar spine regions. Among patients with PVBM, differences in retreatment rates and in pain relief, narcotic use, and toxicity 3 months after randomization were evaluated.Results: Of 909 eligible patients, 235 (26%) had PVBM. Patients with and without PVBM differed in terms of the percentage of men (55% vs 47%, respectively; P = .03) and the proportion of patients with multiple painful sites (57% vs 38%, respectively; P < .01). Among those with PVBM, more patients who received MFRT had multiple sites treated (65% vs 49% for MFRT vs SFRT, respectively; P = .02). There were no statistically significant treatment differences in terms of pain relief (62% vs 70% for MFRT vs SFRT, respectively; P = .59) or freedom from narcotic use (24% vs 27%, respectively; P = .76) at 3 months. Significant differences in acute grade 2 through 4 toxicity (20% vs 10% for MFRT vs SFRT, respectively; P = .01) and acute grade 2 through 4 gastrointestinal toxicity (14% vs 6%, respectively; P = .01) were observed at 3 months, with lower toxicities seen in the patients treated with SFRT. Late toxicity was rare. No myelopathy was recorded. SFRT produced higher 3-year retreatment rates (5% vs 15%; P = .01).Conclusions: Results for the subset of patients with PVBM in the RTOG 94-17 randomized controlled trial were comparable to those for the entire population. SFRT produced less acute toxicity and a higher rate of retreatment than MFRT. SFRT and MFRT resulted in comparable pain relief and narcotic use at 3 months. [ABSTRACT FROM AUTHOR]

Published
2013
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