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14 results on '"Deloye, J."'

1. Measurement of the $^8$B Solar Neutrino Flux Using the Full SNO+ Water Phase

Author

Collaboration, SNO, Allega, A., Anderson, M. R., Andringa, S., Askins, M., Auty, D. J., Bacon, A., Baker, J., Barão, F., Barros, N., Bayes, R., Beier, E. W., Bialek, A., Biller, S. D., Blucher, E., Caden, E., Callaghan, E. J., Chen, M., Cheng, S., Cleveland, B., Cookman, D., Corning, J., Cox, M. A., Dehghani, R., Deloye, J., Depatie, M. M., Di Lodovico, F., Dima, C., Dittmer, J., Dixon, K. H., Esmaeilian, M. S., Falk, E., Fatemighomi, N., Ford, R., Gaur, A., González-Reina, O. I., Gooding, D., Grant, C., Grove, J., Hall, S., Hallin, A. L., Hallman, D., Heintzelman, W. J., Helmer, R. L., Hewitt, C., Howard, V., Hreljac, B., Hu, J., Huang, P., Hunt-Stokes, R., Hussain, S. M. A., Inácio, A. S., Jillings, C. J., Kaluzienski, S., Kaptanoglu, T., Khan, H., Kladnik, J., Klein, J. R., Kormos, L. L., Krar, B., Kraus, C., Krauss, C. B., Kroupová, T., Lake, C., Lebanowski, L., Lefebvre, C., Lozza, V., Luo, M., Maio, A., Manecki, S., Maneira, J., Martin, R. D., McCauley, N., McDonald, A. B., Milton, G., Colina, A. Molina, Morris, D., Mubasher, M., Naugle, S., Nolan, L. J., O'Keeffe, H. M., Gann, G. D. Orebi, Page, J., Paleshi, K., Parker, W., Paton, J., Peeters, S. J. M., Pickard, L., Quenallata, B., Ravi, P., Reichold, A., Riccetto, S., Rose, J., Rosero, R., Semenec, I., Simms, J., Skensved, P., Smiley, M., Smith, J., Svoboda, R., Tam, B., Tseng, J., Vázquez-Jáuregui, E., Veinot, J. G. C., Virtue, C. J., Ward, M., Weigand, J. J., Wilson, J. R., Wilson, J. D., Wright, A., Yang, S., Yeh, M., Ye, Z., Yu, S., Zhang, Y., Zuber, K., and Zummo, A.

Subjects
High Energy Physics - Experiment
Abstract

The SNO+ detector operated initially as a water Cherenkov detector. The implementation of a sealed covergas system midway through water data taking resulted in a significant reduction in the activity of $^{222}$Rn daughters in the detector and allowed the lowest background to the solar electron scattering signal above 5 MeV achieved to date. This paper reports an updated SNO+ water phase $^8$B solar neutrino analysis with a total livetime of 282.4 days and an analysis threshold of 3.5 MeV. The $^8$B solar neutrino flux is found to be $\left(2.32^{+0.18}_{-0.17}\text{(stat.)}^{+0.07}_{-0.05}\text{(syst.)}\right)\times10^{6}$ cm$^{-2}$s$^{-1}$ assuming no neutrino oscillations, or $\left(5.36^{+0.41}_{-0.39}\text{(stat.)}^{+0.17}_{-0.16}\text{(syst.)} \right)\times10^{6}$ cm$^{-2}$s$^{-1}$ assuming standard neutrino oscillation parameters, in good agreement with both previous measurements and Standard Solar Model Calculations. The electron recoil spectrum is presented above 3.5 MeV.

Published
2024

2. Initial measurement of reactor antineutrino oscillation at SNO+

Author

Collaboration, SNO, Allega, A., Anderson, M. R., Andringa, S., Askins, M., Auty, D. J., Bacon, A., Baker, J., Barão, F., Barros, N., Bayes, R., Beier, E. W., Bezerra, T. S., Bialek, A., Biller, S. D., Blucher, E., Caden, E., Callaghan, E. J., Chen, M., Cheng, S., Cleveland, B., Cookman, D., Corning, J., Cox, M. A., Dehghani, R., Deloye, J., Depatie, M. M., Di Lodovico, F., Dima, C., Dittmer, J., Dixon, K. H., Esmaeilian, M. S., Falk, E., Fatemighomi, N., Ford, R., Gaur, A., González-Reina, O. I., Gooding, D., Grant, C., Grove, J., Hall, S., Hallin, A. L., Hallman, D., Heintzelman, W. J., Helmer, R. L., Hewitt, C., Howard, V., Hreljac, B., Hu, J., Huang, P., Hunt-Stokes, R., Hussain, S. M. A., Inácio, A. S., Jillings, C. J., Kaluzienski, S., Kaptanoglu, T., Khan, H., Kladnik, J., Klein, J. R., Kormos, L. L., Krar, B., Kraus, C., Krauss, C. B., Kroupová, T., Lake, C., Lebanowski, L., Lefebvre, C., Lozza, V., Luo, M., Maio, A., Manecki, S., Maneira, J., Martin, R. D., McCauley, N., McDonald, A. B., Mills, C., Milton, G., Colina, A. Molina, Morris, D., Morton-Blake, I., Mubasher, M., Naugle, S., Nolan, L. J., O'Keeffe, H. M., Gann, G. D. Orebi, Page, J., Paleshi, K., Parker, W., Paton, J., Peeters, S. J. M., Pickard, L., Quenallata, B., Ravi, P., Reichold, A., Riccetto, S., Rose, J., Rosero, R., Semenec, I., Simms, J., Skensved, P., Smiley, M., Smith, J., Svoboda, R., Tam, B., Tseng, J., Vázquez-Jáuregui, E., Veinot, J. G. C., Virtue, C. J., Ward, M., Weigand, J. J., Wilson, J. R., Wilson, J. D., Wright, A., Yang, S., Yeh, M., Ye, Z., Yu, S., Zhang, Y., Zuber, K., and Zummo, A.

Subjects
High Energy Physics - Experiment, Nuclear Experiment
Abstract

The SNO+ collaboration reports its first spectral analysis of long-baseline reactor antineutrino oscillation using 114 tonne-years of data. Fitting the neutrino oscillation probability to the observed energy spectrum yields constraints on the neutrino mass-squared difference $\Delta m^2_{21}$. In the ranges allowed by previous measurements, the best-fit $\Delta m^2_{21}$ is (8.85$^{+1.10}_{-1.33}$) $\times$ 10$^{-5}$ eV$^2$. This measurement is continuing in the next phases of SNO+ and is expected to surpass the present global precision on $\Delta m^2_{21}$ with about three years of data.

Published
2024

3. Event-by-event direction reconstruction of solar neutrinos in a high light-yield liquid scintillator

Author

Allega, A, Anderson, MR, Andringa, S, Antunes, J, Askins, M, Auty, DJ, Bacon, A, Baker, J, Barros, N, Barão, F, Bayes, R, Beier, EW, Bezerra, TS, Bialek, A, Biller, SD, Blucher, E, Caden, E, Callaghan, EJ, Chen, M, Cheng, S, Cleveland, B, Cookman, D, Corning, J, Cox, MA, Dehghani, R, Deloye, J, Depatie, MM, Di Lodovico, F, Dittmer, J, Dixon, KH, Falk, E, Fatemighomi, N, Ford, R, Gaur, A, González-Reina, OI, Gooding, D, Grant, C, Grove, J, Hall, S, Hallin, AL, Heintzelman, WJ, Helmer, RL, Hewitt, C, Hreljac, B, Howard, V, Hu, J, Hunt-Stokes, R, Hussain, SMA, Inácio, AS, Jillings, CJ, Kaluzienski, S, Kaptanoglu, T, Khaghani, P, Khan, H, Klein, JR, Kormos, LL, Krar, B, Kraus, C, Krauss, CB, Kroupová, T, Lake, C, Lebanowski, L, Lee, J, Lefebvre, C, Lin, YH, Lozza, V, Luo, M, Maio, A, Manecki, S, Maneira, J, Martin, RD, McCauley, N, McDonald, AB, Mills, C, Milton, G, Morton-Blake, I, Mubasher, M, Colina, A Molina, Morris, D, Naugle, S, Nolan, LJ, O’Keeffe, HM, Gann, GD Orebi, Page, J, Paleshi, K, Parker, W, Paton, J, Peeters, SJM, Pickard, L, Ravi, P, Reichold, A, Riccetto, S, Rigan, M, Rose, J, Rosero, R, Rumleskie, J, Semenec, I, Skensved, P, Smiley, M, and Smith, J

Subjects
Nuclear and Plasma Physics, Physical Sciences
Abstract

The direction of individual B8 solar neutrinos has been reconstructed using the SNO+ liquid scintillator detector. Prompt, directional Cherenkov light was separated from the slower, isotropic scintillation light using time information, and a maximum likelihood method was used to reconstruct the direction of individual scattered electrons. A clear directional signal was observed, correlated with the solar angle. The observation was aided by a period of low primary fluor concentration that resulted in a slower scintillator decay time. This is the first time that event-by-event direction reconstruction in high light-yield liquid scintillator has been demonstrated in a large-scale detector.

Published
2024

4. Event-by-Event Direction Reconstruction of Solar Neutrinos in a High Light-Yield Liquid Scintillator

Author

Allega, A., Anderson, M. R., Andringa, S., Antunes, J., Askins, M., Auty, D. J., Bacon, A., Baker, J., Barros, N., Barão, F., Bayes, R., Beier, E. W., Bezerra, T. S., Bialek, A., Biller, S. D., Blucher, E., Caden, E., Callaghan, E. J., Chen, M., Cheng, S., Cleveland, B., Cookman, D., Corning, J., Cox, M. A., Dehghani, R., Deloye, J., Depatie, M. M., Di Lodovico, F., Dittmer, J., Dixon, K. H., Falk, E., Fatemighomi, N., Ford, R., Gaur, A., Ganzálaz-Reina, O. I., Gooding, D., Grant, C., Grove, J., Hall, S., Hallin, A. L., Heintzelman, W. J., Helmer, R. L., Hewitt, C., Hreljac, B., Howard, V., Hu, J., Hunt-Stokes, R., Hussain, S. M. A., Inácio, A. S., Jillings, C. J., Kaluzienski, S., Kaptanoglu, T., Khaghani, P., Khan, H., Klein, J. R., Kormos, L. L., Krar, B., Kraus, C., Krauss, C. B., Kroupová, T., Lake, C., Lebanowski, L., Lee, J., Lefebvra, C., Lin, Y. H., Lozza, V., Luo, M., Maio, A., Manecki, S., Maneira, J., Martin, R. D., McCauley, N., McDonald, A. B., Mills, C., Milton, G., Morton-Blake, I., Mubasher, M., Colina, A. Molina, Morris, D., Naugle, S., Nolan, L. J., O'Keeffe, H. M., Gann, G. D. Orebi, Page, J., Paleshi, K., Parker, W., Paton, J., Peeters, S. J. M., Pickard, L., Ravi, P., Reichold, A., Riccetto, S., Rigan, M., Rose, J., Rosero, R., Rumleskie, J., Semenec, I., Skensvard, P., Smiley, M., Smith, J., Svoboda, R., Tam, B., Tseng, J., Valder, S., Vázquez-Jáuregui, E., Virtue, C. J., Wang, J., Ward, M., Wilson, J. R., Wilson, J. D., Wright, A., Yanez, J. P., Yang, S., Yeh, M., Ye, Z., Yu, S., Zhang, Y., Zuber, K., and Zummo, A.

Subjects
High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract

The direction of individual $^8$B solar neutrinos has been reconstructed using the SNO+ liquid scintillator detector. Prompt, directional Cherenkov light was separated from the slower, isotropic scintillation light using time information, and a maximum likelihood method was used to reconstruct the direction of individual scattered electrons. A clear directional signal was observed, correlated with the solar angle. The observation was aided by a period of low primary fluor concentration that resulted in a slower scintillator decay time. This is the first time that event-by-event direction reconstruction in high light-yield liquid scintillator has been demonstrated in a large-scale detector., Comment: 6 pages, 6 figures. Accepted manuscript by PRD

Published
2023
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5. Evidence of Antineutrinos from Distant Reactors Using Pure Water at SNO+

Author

Allega, A, Anderson, MR, Andringa, S, Antunes, J, Askins, M, Auty, DJ, Bacon, A, Barros, N, Barão, F, Bayes, R, Beier, EW, Bezerra, TS, Bialek, A, Biller, SD, Blucher, E, Caden, E, Callaghan, EJ, Cheng, S, Chen, M, Cleveland, B, Cookman, D, Corning, J, Cox, MA, Dehghani, R, Deloye, J, Deluce, C, Depatie, MM, Dittmer, J, Dixon, KH, Di Lodovico, F, Falk, E, Fatemighomi, N, Ford, R, Frankiewicz, K, Gaur, A, González-Reina, OI, Gooding, D, Grant, C, Grove, J, Hallin, AL, Hallman, D, Heintzelman, WJ, Helmer, RL, Hu, J, Hunt-Stokes, R, Hussain, SMA, Inácio, AS, Jillings, CJ, Kaluzienski, S, Kaptanoglu, T, Khaghani, P, Khan, H, Klein, JR, Kormos, LL, Krar, B, Kraus, C, Krauss, CB, Kroupová, T, Lam, I, Land, BJ, Lawson, I, Lebanowski, L, Lee, J, Lefebvre, C, Lidgard, J, Lin, YH, Lozza, V, Luo, M, Maio, A, Manecki, S, Maneira, J, Martin, RD, McCauley, N, McDonald, AB, Mills, C, Morton-Blake, I, Naugle, S, Nolan, LJ, O’Keeffe, HM, Gann, GD Orebi, Page, J, Parker, W, Paton, J, Peeters, SJM, Pickard, L, Ravi, P, Reichold, A, Riccetto, S, Richardson, R, Rigan, M, Rose, J, Rosero, R, Rumleskie, J, Semenec, I, Skensved, P, Smiley, M, Svoboda, R, Tam, B, Tseng, J, and Turner, E

Subjects
Nuclear and Plasma Physics, Physical Sciences, SNO+ Collaboration, Mathematical Sciences, Engineering, General Physics, Mathematical sciences, Physical sciences
Abstract

The SNO+ Collaboration reports the first evidence of reactor antineutrinos in a Cherenkov detector. The nearest nuclear reactors are located 240 km away in Ontario, Canada. This analysis uses events with energies lower than in any previous analysis with a large water Cherenkov detector. Two analytical methods are used to distinguish reactor antineutrinos from background events in 190 days of data and yield consistent evidence for antineutrinos with a combined significance of 3.5σ.

Published
2023

6. Evidence of Antineutrinos from Distant Reactors using Pure Water at SNO+

Author

Collaboration, SNO, Allega, A., Anderson, M. R., Andringa, S., Antunes, J., Askins, M., Auty, D. J., Bacon, A., Barros, N., Barao, F., Bayes, R., Beier, E. W., Bezerra, T. S., Bialek, A., Biller, S. D., Blucher, E., Caden, E., Callaghan, E. J., Cheng, S., Chen, M., Cleveland, B., Cookman, D., Corning, J., Cox, M. A., Dehghani, R., Deloye, J., Deluce, C., Depatie, M. M., Dittmer, J., Dixon, K. H., Di Lodovico, F., Falk, E., Fatemighomi, N., Ford, R., Frankiewicz, K., Gaur, A., Gonzalez-Reina, O. I., Gooding, D., Grant, C., Grove, J., Hallin, A. L., Hallman, D., Heintzelman, W. J., Helmer, R. L., Hu, J., Hunt-Stokes, R., Hussain, S. M. A., Inacio, A. S., Jillings, C. J., Kaluzienski, S., Kaptanoglu, T., Khaghani, P., Khan, H., Klein, J. R., Kormos, L. L., Krar, B., Kraus, C., Krauss, C. B., Kroupova, T., Lam, I., Land, B. J., Lawson, I., Lebanowski, L., Lee, J., Lefebvre, C., Lidgard, J., Lin, Y. H., Lozza, V., Luo, M., Maio, A., Manecki, S., Maneira, J., Martin, R. D., McCauley, N., McDonald, A. B., Mills, C., Morton-Blake, I., Naugle, S., Nolan, L. J., O'Keeffe, H. M., Gann, G. D. Orebi, Page, J., Parker, W., Paton, J., Peeters, S. J. M., Pickard, L., Ravi, P., Reichold, A., Riccetto, S., Richardson, R., Rigan, M., Rose, J., Rosero, R., Rumleskie, J., Semenec, I., Skensved, P., Smiley, M., Svoboda, R., Tam, B., Tseng, J., Turner, E., Valder, S., Virtue, C. J., Vazquez-Jauregui, E., Wang, J., Ward, M., Wilson, J. R., Wilson, J. D., Wright, A., Yanez, J. P., Yang, S., Yeh, M., Yu, S., Zhang, Y., Zuber, K., and Zummo, A.

Subjects
Nuclear Experiment, High Energy Physics - Experiment
Abstract

The SNO+ Collaboration reports the first evidence of reactor antineutrinos in a Cherenkov detector. The nearest nuclear reactors are located 240~km away in Ontario, Canada. This analysis uses events with energies lower than in any previous analysis with a large water Cherenkov detector. Two analytical methods are used to distinguish reactor antineutrinos from background events in 190 days of data and yield consistent evidence for antineutrinos with a combined significance of 3.5$\sigma$., Comment: v2: add missing author, add link to supplemental material v3: minor updates to match PRL publication

Published
2022
Full Text
View/download PDF

7. Initial measurement of reactor antineutrino oscillation at SNO+

Author

Collaboration, SNO+, Allega, A., Anderson, M. R., Andringa, S., Askins, M., Auty, D. J., Bacon, A., Baker, J., Barão, F., Barros, N., Bayes, R., Beier, E. W., Bezerra, T. S., Bialek, A., Biller, S. D., Blucher, E., Caden, E., Callaghan, E. J., Chen, M., Cheng, S., Cleveland, B., Cookman, D., Corning, J., Cox, M. A., Dehghani, R., Deloye, J., Depatie, M. M., Di Lodovico, F., Dima, C., Dittmer, J., Dixon, K. H., Esmaeilian, M. S., Falk, E., Fatemighomi, N., Ford, R., Gaur, A., González-Reina, O. I., Gooding, D., Grant, C., Grove, J., Hall, S., Hallin, A. L., Hallman, D., Heintzelman, W. J., Helmer, R. L., Hewitt, C., Howard, V., Hreljac, B., Hu, J., Huang, P., Hunt-Stokes, R., Hussain, S. M. A., Inácio, A. S., Jillings, C. J., Kaluzienski, S., Kaptanoglu, T., Khan, H., Kladnik, J., Klein, J. R., Kormos, L. L., Krar, B., Kraus, C., Krauss, C. B., Kroupová, T., Lake, C., Lebanowski, L., Lefebvre, C., Lozza, V., Luo, M., Maio, A., Manecki, S., Maneira, J., Martin, R. D., McCauley, N., McDonald, A. B., Mills, C., Milton, G., Colina, A. Molina, Morris, D., Morton-Blake, I., Mubasher, M., Naugle, S., Nolan, L. J., O'Keeffe, H. M., Gann, G. D. Orebi, Page, J., Paleshi, K., Parker, W., Paton, J., Peeters, S. J. M., Pickard, L., Quenallata, B., Ravi, P., Reichold, A., Riccetto, S., Rose, J., Rosero, R., Semenec, I., Simms, J., Skensved, P., Smiley, M., Smith, J., Svoboda, R., Tam, B., Tseng, J., Vázquez-Jáuregui, E., Veinot, J. G. C., Virtue, C. J., Ward, M., Weigand, J. J., Wilson, J. R., Wilson, J. D., Wright, A., Yang, S., Yeh, M., Ye, Z., Yu, S., Zhang, Y., Zuber, K., Zummo, A., Collaboration, SNO+, Allega, A., Anderson, M. R., Andringa, S., Askins, M., Auty, D. J., Bacon, A., Baker, J., Barão, F., Barros, N., Bayes, R., Beier, E. W., Bezerra, T. S., Bialek, A., Biller, S. D., Blucher, E., Caden, E., Callaghan, E. J., Chen, M., Cheng, S., Cleveland, B., Cookman, D., Corning, J., Cox, M. A., Dehghani, R., Deloye, J., Depatie, M. M., Di Lodovico, F., Dima, C., Dittmer, J., Dixon, K. H., Esmaeilian, M. S., Falk, E., Fatemighomi, N., Ford, R., Gaur, A., González-Reina, O. I., Gooding, D., Grant, C., Grove, J., Hall, S., Hallin, A. L., Hallman, D., Heintzelman, W. J., Helmer, R. L., Hewitt, C., Howard, V., Hreljac, B., Hu, J., Huang, P., Hunt-Stokes, R., Hussain, S. M. A., Inácio, A. S., Jillings, C. J., Kaluzienski, S., Kaptanoglu, T., Khan, H., Kladnik, J., Klein, J. R., Kormos, L. L., Krar, B., Kraus, C., Krauss, C. B., Kroupová, T., Lake, C., Lebanowski, L., Lefebvre, C., Lozza, V., Luo, M., Maio, A., Manecki, S., Maneira, J., Martin, R. D., McCauley, N., McDonald, A. B., Mills, C., Milton, G., Colina, A. Molina, Morris, D., Morton-Blake, I., Mubasher, M., Naugle, S., Nolan, L. J., O'Keeffe, H. M., Gann, G. D. Orebi, Page, J., Paleshi, K., Parker, W., Paton, J., Peeters, S. J. M., Pickard, L., Quenallata, B., Ravi, P., Reichold, A., Riccetto, S., Rose, J., Rosero, R., Semenec, I., Simms, J., Skensved, P., Smiley, M., Smith, J., Svoboda, R., Tam, B., Tseng, J., Vázquez-Jáuregui, E., Veinot, J. G. C., Virtue, C. J., Ward, M., Weigand, J. J., Wilson, J. R., Wilson, J. D., Wright, A., Yang, S., Yeh, M., Ye, Z., Yu, S., Zhang, Y., Zuber, K., and Zummo, A.

Abstract

The SNO+ collaboration reports its first spectral analysis of long-baseline reactor antineutrino oscillation using 114 tonne-years of data. Fitting the neutrino oscillation probability to the observed energy spectrum yields constraints on the neutrino mass-squared difference $\Delta m^2_{21}$. In the ranges allowed by previous measurements, the best-fit $\Delta m^2_{21}$ is (8.85$^{+1.10}_{-1.33}$) $\times$ 10$^{-5}$ eV$^2$. This measurement is continuing in the next phases of SNO+ and is expected to surpass the present global precision on $\Delta m^2_{21}$ with about three years of data.

Published
2024

8. Evidence of antineutrinos from distant reactors using pure water at SNO

Author

Collaboration, SNO+, Allega, A., Anderson, M. R., Andringa, S., Antunes, J., Askins, M., Auty, D. J., Bacon, A., Barros, N., Barao, F., Bayes, R., Beier, E. W., Bezerra, T. S., Bialek, A., Biller, S. D., Blucher, E., Caden, E., Callaghan, E. J., Cheng, S., Chen, M., Cleveland, B., Cookman, D., Corning, J., Cox, M. A., Dehghani, R., Deloye, J., Deluce, C., Depatie, M. M., Dittmer, J., Dixon, K. H., Di Lodovico, F., Falk, E., Fatemighomi, N., Ford, R., Frankiewicz, K., Gaur, A., Gonzalez-Reina, O. I., Gooding, D., Grant, C., Grove, J., Hallin, A. L., Hallman, D., Heintzelman, W. J., Helmer, R. L., Hu, J., Hunt-Stokes, R., Hussain, S. M. A., Inacio, A. S., Jillings, C. J., Kaluzienski, S., Kaptanoglu, T., Khaghani, P., Khan, H., Klein, J. R., Kormos, L. L., Krar, B., Kraus, C., Krauss, C. B., Kroupova, T., Lam, I., Land, B. J., Lawson, I., Lebanowski, L., Lee, J., Lefebvre, C., Lidgard, J., Lin, Y. H., Lozza, V., Luo, M., Maio, A., Manecki, S., Maneira, J., Martin, R. D., McCauley, N., McDonald, A. B., Mills, C., Morton-Blake, I., Naugle, S., Nolan, L. J., O'Keeffe, H. M., Gann, G. D. Orebi, Page, J., Parker, W., Paton, J., Peeters, S. J. M., Pickard, L., Ravi, P., Reichold, A., Riccetto, S., Richardson, R., Rigan, M., Rose, J., Rosero, R., Rumleskie, J., Semenec, I., Skensved, P., Smiley, M., Svoboda, R., Tam, B., Tseng, J., Turner, E., Valder, S., Virtue, C. J., Vazquez-Jauregui, E., Wang, J., Ward, M., Wilson, J. R., Wilson, J. D., Wright, A., Yanez, J. P., Yang, S., Yeh, M., Yu, S., Zhang, Y., Zuber, K., Zummo, A., and Collaboration, The SNO +

Subjects
High Energy Physics - Experiment (hep-ex), FOS: Physical sciences, General Physics and Astronomy, Nuclear Experiment (nucl-ex), Nuclear Experiment, High Energy Physics - Experiment
Abstract

The SNO+ Collaboration reports the first evidence of reactor antineutrinos in a Cherenkov detector. The nearest nuclear reactors are located 240~km away in Ontario, Canada. This analysis uses events with energies lower than in any previous analysis with a large water Cherenkov detector. Two analytical methods are used to distinguish reactor antineutrinos from background events in 190 days of data and yield consistent evidence for antineutrinos with a combined significance of 3.5$\sigma$., Comment: v2: add missing author, add link to supplemental material v3: minor updates to match PRL publication

Published
2023

9. Evidence of Antineutrinos from Distant Reactors using Pure Water at SNO+

Author

Collaboration, SNO+, Allega, A., Anderson, M. R., Andringa, S., Antunes, J., Askins, M., Auty, D. J., Bacon, A., Barros, N., Barao, F., Bayes, R., Beier, E. W., Bezerra, T. S., Bialek, A., Biller, S. D., Blucher, E., Caden, E., Callaghan, E. J., Cheng, S., Chen, M., Cleveland, B., Cookman, D., Corning, J., Cox, M. A., Dehghani, R., Deloye, J., Deluce, C., Depatie, M. M., Dittmer, J., Dixon, K. H., Di Lodovico, F., Falk, E., Fatemighomi, N., Ford, R., Frankiewicz, K., Gaur, A., Gonzalez-Reina, O. I., Gooding, D., Grant, C., Grove, J., Hallin, A. L., Hallman, D., Heintzelman, W. J., Helmer, R. L., Hu, J., Hunt-Stokes, R., Hussain, S. M. A., Inacio, A. S., Jillings, C. J., Kaluzienski, S., Kaptanoglu, T., Khaghani, P., Khan, H., Klein, J. R., Kormos, L. L., Krar, B., Kraus, C., Krauss, C. B., Kroupova, T., Lam, I., Land, B. J., Lawson, I., Lebanowski, L., Lee, J., Lefebvre, C., Lidgard, J., Lin, Y. H., Lozza, V., Luo, M., Maio, A., Manecki, S., Maneira, J., Martin, R. D., McCauley, N., McDonald, A. B., Mills, C., Morton-Blake, I., Naugle, S., Nolan, L. J., O'Keeffe, H. M., Gann, G. D. Orebi, Page, J., Parker, W., Paton, J., Peeters, S. J. M., Pickard, L., Ravi, P., Reichold, A., Riccetto, S., Richardson, R., Rigan, M., Rose, J., Rosero, R., Rumleskie, J., Semenec, I., Skensved, P., Smiley, M., Svoboda, R., Tam, B., Tseng, J., Turner, E., Valder, S., Virtue, C. J., Vazquez-Jauregui, E., Wang, J., Ward, M., Wilson, J. R., Wilson, J. D., Wright, A., Yanez, J. P., Yang, S., Yeh, M., Yu, S., Zhang, Y., Zuber, K., Zummo, A., Collaboration, SNO+, Allega, A., Anderson, M. R., Andringa, S., Antunes, J., Askins, M., Auty, D. J., Bacon, A., Barros, N., Barao, F., Bayes, R., Beier, E. W., Bezerra, T. S., Bialek, A., Biller, S. D., Blucher, E., Caden, E., Callaghan, E. J., Cheng, S., Chen, M., Cleveland, B., Cookman, D., Corning, J., Cox, M. A., Dehghani, R., Deloye, J., Deluce, C., Depatie, M. M., Dittmer, J., Dixon, K. H., Di Lodovico, F., Falk, E., Fatemighomi, N., Ford, R., Frankiewicz, K., Gaur, A., Gonzalez-Reina, O. I., Gooding, D., Grant, C., Grove, J., Hallin, A. L., Hallman, D., Heintzelman, W. J., Helmer, R. L., Hu, J., Hunt-Stokes, R., Hussain, S. M. A., Inacio, A. S., Jillings, C. J., Kaluzienski, S., Kaptanoglu, T., Khaghani, P., Khan, H., Klein, J. R., Kormos, L. L., Krar, B., Kraus, C., Krauss, C. B., Kroupova, T., Lam, I., Land, B. J., Lawson, I., Lebanowski, L., Lee, J., Lefebvre, C., Lidgard, J., Lin, Y. H., Lozza, V., Luo, M., Maio, A., Manecki, S., Maneira, J., Martin, R. D., McCauley, N., McDonald, A. B., Mills, C., Morton-Blake, I., Naugle, S., Nolan, L. J., O'Keeffe, H. M., Gann, G. D. Orebi, Page, J., Parker, W., Paton, J., Peeters, S. J. M., Pickard, L., Ravi, P., Reichold, A., Riccetto, S., Richardson, R., Rigan, M., Rose, J., Rosero, R., Rumleskie, J., Semenec, I., Skensved, P., Smiley, M., Svoboda, R., Tam, B., Tseng, J., Turner, E., Valder, S., Virtue, C. J., Vazquez-Jauregui, E., Wang, J., Ward, M., Wilson, J. R., Wilson, J. D., Wright, A., Yanez, J. P., Yang, S., Yeh, M., Yu, S., Zhang, Y., Zuber, K., and Zummo, A.

Abstract

The SNO+ Collaboration reports the first evidence of reactor antineutrinos in a Cherenkov detector. The nearest nuclear reactors are located 240~km away in Ontario, Canada. This analysis uses events with energies lower than in any previous analysis with a large water Cherenkov detector. Two analytical methods are used to distinguish reactor antineutrinos from background events in 190 days of data and yield consistent evidence for antineutrinos with a combined significance of 3.5$\sigma$., Comment: v2: add missing author, add link to supplemental material v3: minor updates to match PRL publication

Published
2022
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14. Dynamic docking of small molecules targeting RNA CUG repeats causing myotonic dystrophy type 1.

Author

Wang KW, Riveros I, DeLoye J, and Yildirim I

Subjects
Humans, RNA genetics, RNA metabolism, Myotonic Dystrophy genetics, Myotonic Dystrophy metabolism
Abstract

Expansion of RNA CUG repeats causes myotonic dystrophy type 1 (DM1). Once transcribed, the expanded CUG repeats strongly attract muscleblind-like 1 (MBNL1) proteins and disturb their functions in cells. Because of its unique structural form, expanded RNA CUG repeats are prospective drug targets, where small molecules can be utilized to target RNA CUG repeats to inhibit MBNL1 binding and ameliorate DM1-associated defects. In this contribution, we developed two physics-based dynamic docking approaches (DynaD and DynaD/Auto) and applied them to nine small molecules known to specifically target RNA CUG repeats. While DynaD uses a distance-based reaction coordinate to study the binding phenomenon, DynaD/Auto combines results of umbrella sampling calculations performed on 1 × 1 UU internal loops and AutoDock calculations to efficiently sample the energy landscape of binding. Predictions are compared with experimental data, displaying a positive correlation with correlation coefficient (R) values of 0.70 and 0.81 for DynaD and DynaD/Auto, respectively. Furthermore, we found that the best correlation was achieved with MM/3D-RISM calculations, highlighting the importance of solvation in binding calculations. Moreover, we detected that DynaD/Auto performed better than DynaD because of the use of prior knowledge about the binding site arising from umbrella sampling calculations. Finally, we developed dendrograms to present how bound states are connected to each other in a binding process. Results are exciting, as DynaD and DynaD/Auto will allow researchers to utilize two novel physics-based and computer-aided drug-design methodologies to perform in silico calculations on drug-like molecules aiming to target complex RNA loops., Competing Interests: Declaration of interests The authors declare no competing interests., (Copyright © 2022 Biophysical Society. Published by Elsevier Inc. All rights reserved.)

Published
2023
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