Author: "Delgado JM" - Searchworks@Jio Institute Digital Library Search Results

279 results on '"Delgado JM"'

1. Nonlinear Observer Based Control Design for an Under-actuated Compliant Robotic Hand

Author: Garcia-Rosas, R, Portella-Delgado, JM, Tan, Y, NESIC, D, Garcia-Rosas, R, Portella-Delgado, JM, Tan, Y, and NESIC, D
Abstract: This work aims at designing control algorithms for an under-actuated compliant adaptive prosthetic hand to perform a complex task of grasping and manipulating of an unknown object. As multiple objectives are considered, if one controller is designed for one control objective, a hybrid controller is needed to coordinate different controllers to perform complex tasks. This work thus tries to apply recently developed framework of System of Funnels to the underactuated compliant adaptive prosthetic hand to design this hybrid controller. In order to apply System of Funnels, each controller has to have the flexibility to obtain any given domain of attraction by tuning its parameters. This paper proposed nonlinear observer based PID controllers for Grasp Approach and Grasp Stabilization. The nonlinear observer estimates the needed velocity of the under-actuated compliant adaptive prosthetic hand. By tuning parameters of PID controller and nonlinear observers appropriately, any desired domain of attraction for each control objective can be achieved. Our next step is to design some manipulation controller with adjustable domain of attraction in order to apply the framework of System of Funnels.
Published: 2016

2. Synthesis and Characterization of an Open-Framework Antimony(III) Phosphate: [H3N(CH2)2NH3]1.5[(SbO)2(SbF)2(PO4)3]

Author: Brian A. Adair, Anthony K. Cheetham, Díaz De Delgado G, and Delgado Jm
Subjects: chemistry.chemical_compound, Antimony, Chemistry, chemistry.chemical_element, General Chemistry, Phosphate, Open framework, Catalysis, Nuclear chemistry, Characterization (materials science)
Published: 2000
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3. Paralisi monolaterale, isolata, reversibile del nervo ipoglosso

Author: BRUZON DELGADO JM, Marioni, Gino, MARCHESE RAGONA, R, and Staffieri, Alberto
Published: 2003

4. Phytochemical and pharmacological screening of extracts from Gunnera tinctoria Mol., a native chilean plant

Author: Rodríguez-Díaz, M, primary, Delgado, JM, additional, Torres, F, additional, Sandoval, C, additional, Rodríguez, S, additional, Delporte, C, additional, and Ross, C, additional
Published: 2013
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5. Intraoperative radiation therapy in malignant glioma: early clinical results

Author: José Samblás, J.C. Bustos, Felipe A. Calvo, G. Donckaster, Ortiz de Urbina D, José A. Gutiérrez-Díaz, Delgado Jm, I. García-Berrocal, and Manuel Santos
Subjects: Adult, Male, medicine.medical_specialty, Adolescent, medicine.medical_treatment, Recurrent Glioma, Glioma, medicine, Humans, Intraoperative radiation therapy, Aged, Intraoperative Care, business.industry, Brain Neoplasms, General Medicine, Middle Aged, medicine.disease, Primary tumor, Surgery, Clinical trial, Radiation therapy, Neurology, Tumor progression, Female, Radiotherapy, Adjuvant, Neurology (clinical), Radiology, Neoplasm Recurrence, Local, business, Anaplastic astrocytoma, Follow-Up Studies
Abstract: Intraoperative radiation therapy (IORT) with high energy electron beams is a treatment modality that has been included in multimodal programs in oncology to improve local tumor control. From August 1991 to December 1993, 17 patients with primary (8) or recurrent (9) high grade malignant gliomas, anaplastic astrocytoma (4), anaplastic oligodendroglioma (6) and glioblastoma multiforme (7), underwent surgical resection and a single dose of 10-20 Gy intraoperative radiation therapy was delivered in tumor bed. Fourteen patients received either pre-operative (8) or post-operative (6) external beam radiation therapy. Primary gliomas: 18-months actuarial survival rate has been 56% (range: 1-21+ months) and the median survival time has not yet been achieved. Four patients developed tumor progression (median time to tumor progression: 9 months). Recurrent gliomas: 18-months actuarial survival rate and median survival time has been 47% and 13 months (range: 6-32+ months) respectively. The median time to tumor progression was 11 months. No IORT related mortality has been observed. IORT is an attractive, tolerable and feasible treatment modality as antitumoral intensification procedure in high grade malignant gliomas.
Published: 1995

6. Cardiovascular reflexes in patients with malignant disease

Author: J. M. Vicent, Delgado Jm, Martín R, R. Manzanares, Matías-Guiu J, Moltó Jm, and R. Insa
Subjects: Male, Reflex, Stretch, medicine.medical_specialty, Pathology, Neurology, Valsalva Maneuver, Physical examination, Dermatology, Autonomic Nervous System, Heart Rate, Neoplasms, Reflex, medicine, Humans, Neuroradiology, Aged, medicine.diagnostic_test, business.industry, General Neuroscience, Multiple sclerosis, Hemodynamics, Magnetic resonance imaging, General Medicine, Middle Aged, medicine.disease, Psychiatry and Mental health, Cardiovascular reflexes, Female, Neurology (clinical), Neurosurgery, Radiology, Abnormality, business
Abstract: Magnetic resonance imaging (MRI) has had a major impact on the diagnosis of multiple sclerosis (MS). In addition serial MRI studies help to reveal a new aspect of measurable activity in MS. The degree of activity shown by serial MRI studies is considerably greater than the degree of activity indicated by history and physical examination. In addition, the extent of the MRI abnormalities can be measured by outlining the lesions and summing the areas of abnormality slice by slice. In the future careful, however, clinical follow-up studies must be done in order to identify the prognostic implications of these MRI data. At this time MRI evaluation techniques are considered a necessary adjunct method of assessment of disease activity for MS therapeutic trials. MRI methods are complementary to clinical methods and measure an index of extent of disease that is undetectable to clinical methods.
Published: 1992

7. Operant conditioning of EEG in the unrestrained chimpanzee

Author: Johnston Vs, Delgado Jm, Jan D. Wallace, and Bradley Rj
Subjects: medicine.medical_specialty, medicine.diagnostic_test, General Neuroscience, Reticular Formation, Electroencephalography, Haplorhini, Audiology, Amygdala, Odorants, medicine, Animals, Conditioning, Operant, Operant conditioning, Neurology (clinical), Psychology
Published: 1969

8. Metallothionein-I overexpression rescues partly the phenotype of the APP2576 mouse model of Alzheimer disease

Author: Hidalgo, J., Giralt, M., Javier Carrasco, Manso, J., Florit, S., Quintana, A., Molinero, A., Penkowa, M., Lopez, Jc, Delgado, Jm, Adlard, Pa, and Bush, Ai

9. Intracerebral temperatures in free-moving cats

Author: Delgado, JM, primary and Hanai, T, additional
Published: 1966
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10. Pooled analysis of who surgical safety checklist use and mortality after emergency laparotomy

Author: Thomas, Hannah S., Weiser, Thomas G., Drake, Thomas M., Knight, Stephen R., Fairfield, Cameron, Ademuyiwa, Adesoji O., Aguilera, Maria Lorena, Alexander, Philip, Al-Saqqa, Sara W., Borda-Luque, Giuliano, Costas-Chavarri, Ainhoa, Ntirenganya, Faustin, Fitzgerald, J. Edward, Fergusson, Stuart J., Glasbey, James, Ingabire, J. C. Allen, Ismail, Lawani, Salem, Hosni Khairy, Kojo, Anyomih Theophilus Teddy, Lapitan, Marie Carmela, Lilford, Richard, Mihaljevic, Andre L., Morton, Dion, Mutabazi, Alphonse Zeta, Nepogodiev, Dmitri, Adisa, Adewale O., Ots, Riinu, Pata, Francesco, Pinkney, Thomas, Poskus, Tomas, Qureshi, Ahmad Uzair, Ramos-De la Medina, Antonio, Rayne, Sarah, Shaw, Catherine A., Shu, Sebastian, Spence, Richard, Smart, Neil, Tabiri, Stephen, Bhangu, Aneel, Harrison, Ewen M., Verjee, Azmina, Runigamugabo, Emmy, Altamini, Afnan, Cornick, Jen, Jaffry, Zahra, Khatri, Chetan, Kirby, Andrew, Mohan, Midhun, Recinos, Gustavo, Soreide, Kjetil, Bhang, Aneel, Gobin, Neel, Freitas, Ana Vega, Hall, Nigel, Kim, Sung-Hee, Negida, Ahmed, Khairy, Hosni, Chapman, Stephen J., Arnaud, Alexis P., Manipal, Cutting Edge, Amandito, Radhian, Shawki, Marwan, Hanrahan, Michael, Zilinskas, Justas, Roslani, April Camilla, Goh, Cheng Chun, Irwin, Gareth, Luque, Laura, Shiwani, Hunain, Altamimi, Afnan, Alsaggaf, Mohammed Ubaid, Jeyakumar, Jenifa, Cengiz, Yucel, Raptis, Dmitri A., Glasbey, James C., Modolo, Maria Marta, Iyer, Dushyant, King, Sebastian, Arthur, Tom, Nahar, Sayeda Nazmum, Waterman, Ade, Walsh, Michael, Agarwal, Arnav, Zani, Augusto, Firdouse, Mohammed, Rouse, Tyler, Liu, Qinyang, Camilo Correa, Juan, Talving, Peep, Worku, Mengistu, Arnaud, Alexis, Kalles, Vassilis, Kumar, Basant, Kumar, Sunil, Quek, Roy, Ansaloni, Luca, Altibi, Ahmed, Venskutonis, Donatas, Whitaker, John, Msosa, Vanessa, Tew, Yong Yong, Farrugia, Alexia, Borg, Elaine, Bentounsi, Zineb, Gala, Tanzeela, Al-Slaibi, Ibrahim, Tahboub, Haya, Alser, Osaid H., Romani, Diego, Shu, Sebestian, Major, Piotr, Mironescu, Aurel, Bratu, Matei, Kourdouli, Amar, Ndajiwo, Aliyu, Altwijri, Abdulaziz, Gudal, Ahmad, Jubran, Al Faifi, Seisay, Sam, Lieske, Bettina, Ortega, Irene, Senanayake, Kithsiri J., Abdulbagi, Omar, Raptis, Dmitri, Altinel, Yuksel, Kong, Chia, Teasdale, Ella, Stoddart, Michael, Kabariti, Rakan, Suresh, Sukrit, Gash, Katherine, Narayanan, Ragavan, Maimbo, Mayaba, Fermani, Claudio, Balmaceda, Ruben, Macdermid, Ewan, Chenn, Roxanne, Yong, Cheryl Ou, Edye, Michael, Jarmin, Martin, D'amours, Scott K., Youssef, Daniel, Phillips, Nicholas, Brown, Jason, George, Robert, Koh, Cherry, Warren, Oliver, Hanley, Isaac, Dickfos, Marilla, Nawara, Clemens, Ofner, Dietmar, Primavesi, Florian, Mitul, Ashrarur Rahman, Mahmud, Khalid, Hussain, Margub, Hakim, Hafiz, Kumar, Tapan, Oosterkamp, Antje, Assouto, Pamphile A., Lawani, Ismail, Souaibou, Yacoubou Imorou, Tun, Aung Kyaw, Chong, Chean Leung, Devadasar, Giridhar H., Qadir, Muhammad Rashid Minhas, Aung, Kyaw Phyo, Yeo, Lee Shi, Palomino Castillo, Vanessa Dina, Munhoz, Monique Moron, Moreira, Gisele, Barros De Castro Segundo, Luiz Carlos, Khouri Ferreira, Salim Anderson, Careta, Maira Cassa, Kim, Stella Binna, De Sousa, Alexandre Venancio, Lazzarini Cury, Alyne Daltri, Soares Miguel, Gustavo Peixoto, Carreiro De Freitas, Ana Vega, Silvestre, Barbara Pereira, Vianna, Julia Guasti Pinto, Felipe, Carolina Oliveira, Valente Laufer, Luis Alberto, Altoe, Fernanda, Da Silva, Luana Ayres, Pimenta, Marina Luiza, Giuriato, Thiago Fernandes, Bezerra Morais, Paulo Alves, Luiz, Jessica Souza, Araujo, Rafael, Menegussi, Juliana, Leal, Marisa, Barroso de Lima, Caio Vinicius, Tatagiba, Luiza Sarmento, Leal, Antonio, dos Santos, Diogo Vinicius, Fraga, Gustavo Pereira, Simoes, Romeo Lages, Stock, Simon, Nigo, Samuel, Kabba, Juana, Ngwa, Tagang Ebogo, Brown, James, Azzie, Georges, Kushwaha, Sameer, Bailey, Karen, Cameron, Brian, Livingston, Michael, Horobjowsky, Alexandre, Deckelbaum, Dan L., Razek, Tarek, Marinkovic, Boris, Grasset, Eugenio, D'aguzan, Nicole, Jimenez, Julio, Macchiavello, Roberto, Zhang, Zhongtao, Guo, Wei, Oh, Junyeong, Zheng, Fei, Montes, Irene, Sierra, Sebastian, Mendez, Manuela, Isabel Villegas, Maria, Mendoza Arango, Maria Clara, Mendoza, Ivan, Naranjo Aristizaibal, Fred Alexander, Montoya Botero, Jaime Andres, Quintero Riaza, Victor Manuel, Restrepo, Jakeline, Morales, Carlos, Cruz, Herman, Munera, Alejandro, Karlo, Robert, Domini, Edgar, Mihanovic, Jakov, Radic, Mihael, Zamarin, Kresimir, Pezelj, Nikica, Hache-Marliere, Manuel, Lemaire, Sylvia Batista, Rivas, Ruben, Khyrallh, Ahmed, Hassan, Ahamed, Shimy, Gamal, Fahmy, Mohamed A. Baky, Nabawi, Ayman, Elfil, Mohamed, Ghoneem, Mohamed, Gohar, Muhammad El-Saied Ahmad Muhammad, Asal, Mohamed, Abdelkader, Mostafa, Gomah, Mahmoud, Rashwan, Hayssam, Karkeet, Mohamed, Gomaa, Ahmed, Hasan, Amr, Elgebaly, Ahmed, Saleh, Omar, Fattah, Ahmad Abdel, Gouda, Abdullah, Elshafay, Abd Elrahman, Gharib, Abdalla, Menshawy, Ahmed, Hanafy, Mohammed, Al-Mallah, Abdullah, Abdulgawad, Mahmoud, Baheeg, Mohamad, Alhendy, Mohammed, AbdelFattah, Ibrahim, Kenibar, Abdalla, Osman, Omar, Gemeah, Mostafa, Mohammed, Ahmed, Adel, Abdalrahman, Mohammed, Abdelrahman, Sayed, Abdelrahman, Abozaid, Mohamed, Kotb, Ahmed Hafez El-Badri, Ata, Ali Amin Ahmed, Nasr, Mohammed, Alkammash, Abdelrahman, Saeed, Mohammed, Abd El Hamid, Nader, Attia, Attia Mohamed, Abd El Galeel, Ahmed, Elbanby, Eslam, El-Dien, Khalid Salah, Hantour, Usama, Alahmady, Omar, Mansour, Billal, Elkorashy, Amr Muhammad, Taha, Emad Mohamed Saeed, Lasheen, Kholod Tarek, Elkolaly, Salma Said, Abdel-Wahab, Nehal Yosri Elsayed, Abozyed, Mahmoud Ahmed Fathi, Adel, Ahmed, Saeed, Ahmed Moustafa, El Sayed, Gehad Samir, Youssif, Jehad Hassan, Ahmed, Soliman Magdy, El-Shahat, Nermeen Soubhy, Khedr, Abd El-Rahman Hegazy, Elsebaaye, Abdelrhman Osama, Elzayat, Mohamed, Abdelraheim, Mohamed, Elzayat, Ibrahim, Warda, Mahmoud, El Deen, Khaled Naser, Elnemr, Abdelrhman Essam, Salah, Omar, Abbas, Mohamed, Rashad, Mona, Elzayyat, Ibrahim, Hemeda, Dalia, Tawfik, Gehad, Salama, Mai, Khaled, Hazem, Seisa, Mohamed, Elshaer, Kareem, Hussein, Abdelfatah, Elkhadrawi, Mahmoud, Afifi, Ahmed Mohamed, Ebrahim, Osama Saadeldeen, Metwally, Mahmoud Mohamed, Elmelegy, Rowida, Elsawahly, Diaa Moustafa Elbendary, Safa, Hisham, Nofal, Eman, Elbermawy, Mohamed, Ghazy, Ahmed Abdelmotaleb, Samih, Hisham, Abdelgelil, Asmaa, Abdelghany, Sarah, El Kholy, Ahmed, Aboraya, Metwally, Elkady, Fatma, Salma, Mahmoud, Samy, Sarah, Fakher, Reem, Aboarab, Aya, Samir, Ahmed, Sakr, Ahmed, Haroun, Abdelrahman, Al-Aarag, Asmaa Abdel-Rahman, Elkholy, Ahmed, Elshanwany, 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Solaiman, Mosad, Ahmed, Tolba, Hager, Elsorogy, Diaa Eldin Abdelazeem Amin, Mostafa, Hassan Ali, Omar, Amira Atef, Abd El Hameed, Ola Sherief, Lasheen, Ahmed, Abd El Salam, Yasser, Morsi, Ashraf, Ismail, Mohammed, El-badawy, Hager Ahmed, Amer, Mohamed A., El-Hamouly, Ahmed Sabry, Attallah, Noura A., Mosalum, Omnia, Afandy, Ahmed, Mokhtar, Ahmed, Abouelnasr, Alaa, Ayad, Sara, Shaker, Ramdan, Sakr, Rokia, Shaker, Ramadan, Amreia, Mahmoud, Elsobky, Soaad, Mustafa, Mohamed, El Magd, Ahmed Abo, Marey, Abeer, Hafez, Amr Tarek, Zalabia, Mohamed F., Mohamed, Mohamed Moamen, Fadel, Amr, Ahmed, Emad Ali, Ali, Ahmad, Alwafai, Mohammad Ghassan, Dwydar, Abdullah, Kharsa, Sara, Mamdouh, Ehab, El-Sheemy, Hatem, AlYoussef, Ibrahim, Aly, Abouelatta Khairy, Aldalaq, Ahmad, Alnawam, Ehab, Alkhabbaz, Dalia, Saad, Mahmoud, Hussein, Shady, Elazayem, Ahmed Abo, Meshref, Ahmed, Elashmawy, Marwa, Mousa, Mohammed, Nashaat, Ahmad, Ghanem, Sara, Elsayed, Zaynab M., Elwaey, Aya, Elkadsh, Iman, Darweesh, Mariam, Mohameden, Ahmed, Hafez, Mennaallah, Badr, Ahmed, Badwy, Assmaa, Abd El Slam, Mohamed, Elazoul, Mohamed, Al-Nahrawi, Safwat, Eldamaty, Lotfy, Nada, Fathee, Ameen, Mohamed, Hagar, Aya, Elsehimy, Mohamed, Aboraya, Mohammad, Dawoud, Hossam, El Mesery, Shorouk, El Gendy, Abeer, Abdelkareem, Ahmed, Marey, Ahmed Safwan, Allam, Mostafa, Shehata, Sherif, Abozeid, Khaled, Elshobary, Marwa, Fahiem, Ahmed, Sarsik, Sameh, Hashish, Amel, Zidan, Mohamed, Hashish, Mohamed, Aql, Shaimaa, Elhendawy, Abdelaziz Osman Abdelaziz, Husseini, Mohamed, Kasem, Esraa, Gheith, Ahmed, Elfouly, Yasmin, Soliman, Ahmed Ragab, Ibrahim, Yasmein, Elfouly, Nesma, Fawzy, Ahmed, Hassan, Ahmed, Rashid, Mohammad, Elsherbiny, Abdallah Salah, Sieda, Basem, Badwi, Nermin M., Mohammed, Mohammed Mustafa Hassan, Mohamed, Osama, Habeeb, Mohammad Abdulkhalek, Starr, Nichole, Desta, Semay, Wondimu, Sahlu, Abebe, Nebyou Seyoum, Thomas, Efeson, Asele, Frehun Ayele, Dabessa, Daniel, Abebe, Nebiyou Seyoum, Zerihun, Abebe Bekele, Mentula, Panu, Leppaniemi, Ari, Sallinen, Ville, Scalabre, Aurelien, Frade, Fernanda, Irtan, Sabine, Graffeille, Vivien, Gaignard, Elodie, Alimi, Quentin, Graffieille, Vivien, Abbo, Olivier, Mouttalib, Sofia, Bouali, Ourdia, Hervieux, Erik, Aigrain, Yves, Botto, Nathalie, Faure, Alice, Fievet, Lucile, Panait, Nicoleta, Eyssartier, Emilie, Schmitt, Francoise, Podevin, Guillaume, Parent, Valentine, Martin, Amandine, Arnaud, Alexis Pierre, Muller, Cecile, Bonnard, Arnaud, Peycelon, Matthieu, Abantanga, Francis, Boakye-Yiadom, Kwaku, Bukari, Mohammed, Owusu, Frank, Awuku-Asabre, Joseph, Bray, Lemuel Davies, Lytras, Dimitrios, Psarianos, Kyriakos, Bamicha, Anastasia, Kefalidi, Eirini, Gemenetzis, Georgios, Dervenis, Christos, Gouvas, Nikolaos, Agalianos, Christos, Kontos, Michail, Kouraklis, Gregory, Karousos, Dimitrios, Germanos, Stylianos, Marinos, Constantinos, Anthoulakis, Christos, Nikoloudis, Nikolaos, Mitroudis, Nikolaos, Estupinian, Sergio, Forno, Walter, Arevalo Azmitia, Jose Rene, Ramarez Cabrera, Carla Cecilia, Guevara, Romeo, Aguilera, Maria, Mendez, Napoleon, Azmitia Mendizabal, Cesar Augusto, Ramazzini, Pablo, Contreras Urquizu, Mario, Tale, Fernando, Soley, Rafael, Barrios, Emanuel, Marroquin Rodriguez, Daniel Estuardo, Perez Velasquez, Carlos Ivan, Contreras Merida, Sara Maria, Regalado, Francisco, Lopez, Mario, Siguantay, Miguel, Lam, Fong Yee, Szeto, Kylie Joan-Yi, Szeto, Charing Cheuk Ling, Li, Wing Sum, Li, Kieran Ka Kei, Leung, Man Fung, Mak, Tony, Ng, Simon, Prasad, S. S., Kirishnan, Anand, Gyanchandani, Nidhi, Kumar, Bylapudi Seshu, Rangarajan, Muthukumaran, Bhat, Sriram, Sreedharan, Anjana, Kinnera, S. V., Reddy, Yella, Venugopal, Caranj, Mittal, Abhishek, Nadkarni, Shravan, Lakshmi, Harish Neelamraju, Malik, Puneet, Limaye, Neel, Pai, Srinivas, Jain, Pratik, Khajanchi, Monty, Satoskar, Savni, Satoskar, Rajeev, Bin Mahamood, Abid, Sutanto, Eldaa Prisca Refianti, Soeselo, Daniel Ardian, Tedjaatmadja, Chintya, Rahmawati, Fitriana Nur, Mayasari, Maria, Al-Hasani, Ruqaya Kadhim Mohammed Jawad, Al-Hameedi, Hasan Ismael Ibraheem, Ibraheem, Hasan Ismael, Al-Azraqi, Israa Abdullah Aziz, Sabeeh, Lubna, Kamil, Rahma, Telfah, Muwaffaq Mezeil, Rasendran, Amoudtha, Sheehan, Jacqueline, Kerley, Robert, Normile, Caoimhe, Gilbert, Richard William, Song, Jiheon, Dablouk, Mohamed, Mauro, Linnea, Dablouk, Mohammed Osman, Kielty, Paul, Marks, Eleanor, Gosling, Simon, Mccarthy, Michelle, Rasndran, Amoudtha, Mirghani, Diya, Naqvi, Syed Altaf, Wong, Chee Siong, Chung, Siyi, D'cruz, Reuban, Cahill, Ronan, Gosling, Simon George, Fahy, Ciara, Cadogan, Diana Duarte, Powell, Anna, Gilbert, Richard, Clifford, Caroline, Driscoll, Aoife, Paul, Stassen, Lee, Chris, Bowe, Ross, Hutch, William, Mohan, Helen, O'neill, Maeve, Mealy, Kenneth, Danelli, Piergiorgio, Bondurri, Andrea, Maffioli, Anna, Pasini, Mario, Pata, Giacomo, Roncali, Stefano, Silvani, Paolo, Carlucci, Michele, Faccincani, Roberto, Bonavina, Luigi, Macchitella, Yuri, Ceriani, Chiara, Tugnoli, Gregorio, Di Saverio, Salomone, Khattab, Khaled, Paludi, Miguel Angel, Pata, Domenica, Cloro, Luigi Maria, Allegri, Andrea, Coccolini, Federico, Veronese, Ezio, Bortolasi, Luca, Hasheminia, Alireza, Nastri, Giacomo, Dal Canto, Massimiliano, Cucumazzo, Stefano, Benevento, Angelo, Tessera, Gaetano, Grandinetti, Pier Paolo, Maniscalco, Alessio, Lamanna, Giovanni Luca, Turati, Luca, Sgroi, Giovanni, Rausa, Emanuele, Villa, Roberta, Monteleone, Michela, Merlini, David, Grassi, Veronica, Cirocchi, Roberto, Cacurri, Alban, Waleed, Hamza, Diab, Ahmed, Elzowawi, Fathi, Jokubauskas, Mantas, Varkalys, Karolis, Pranevicius, Robertas, Ambrozeviciute, Viktorija, Juciute, Simona, Skardziukaite, Auste, Bradulskis, Saulius, Urbanavicius, Linas, Austraite, Aiste, Riauka, Romualdas, Dambrauskas, Zilvinas, Karumnas, Paulius, Urniezius, Zigmantas, Zilinskiene, Reda, Rudzenskaite, Anele, Usaityte, Ausrine, Montrimaite, Margarita, Kaselis, Nerijus, Strazdas, Andrius, Jokubonis, Kristijonas, Maceviciute, Kornelija, Beisa, Virgilijus, Strupas, Kestutis, Laugzemys, Erikas, Kolosov, Andrej, Jotautas, Valdemaras, Rakita, Ignas, Mikalauskas, Saulius, Kazanavicius, Darius, Rackauskas, Rokas, Rakauskas, Ritauras, Preckailaite, Egle, Coomber, Ross, Johnson, Kenneth, Nowers, Jennifer, Periasammy, Dineshwary, Salleh, Afizah, Das, Andre, Tze, Reuben Goh Ern, Kumar, Milaksh Nirumal, Abdullah, Nik Azim Nik, Kosai, Nik Ritza, Taher, Mustafa, Rajan, Reynu, Chong, Hoong Yin, Agius, Marija, Bezzina, Maureen, Bugeja, Roberta, Vella-Baldacchino, Martinique, Spina, Andrew, Psaila, Josephine, Francois-Coridon, Helene, Tolg, Cecilia, Colombani, Jean-Francois, Diaz-Zorrilla, Carmina, Ramos-De La Medina, Antonio, Corro-Diaz Gonzalez, Samantha, Jacobe, Mario, Mapasse, Domingos, Snyder, Elizabeth, Oumer, Ramadan, Osman, Mohammed, Mohammad, Aminu, Anyanwu, Lofty-John, Sheshe, Abdulrahman, Adesina, Alaba, Faturoti, Olubukola, Taiwo, Ogechukwu, Ibrahim, Muhammad Habib, Nasir, Abdulrasheed A., Suleiman, Siyaka Itopa, Adeniyi, Adewale, Adesanya, Opeoluwa, Adebanjo, Ademola, Osuoji, Roland, Atobatele, Kazeem, Ogunyemi, Ayokunle, Williams, Omolara, Oludara, Mobolaji, Oshodi, Olabode, Ademuyiwa, Adesoji, Lawal, AbdulRazzaq Oluwagbemiga, Alakaloko, Felix, Elebute, Olumide, Osinowo, Adedapo, Bode, Christopher, Adesuyi, Abidemi, Tade, Adesoji, Adekoya, Adeleke, Nwokoro, Collins, Ayandipo, Omobolaji O., Lawal, Taiwo Akeem, Ajao, Akinlabi E., Ali, Samuel Sani, Odeyemi, Babatunde, Olori, Samson, Popoola, Ademola, Adeyeye, Ademola, Adeniran, James, Lossius, William J., Havemann, Ingemar, Thorsen, Kenneth, Narvestad, Jon Kristian, Wold, Trude Beate, Nymo, Linn, Elsiddig, Mohammed, Dar, Manzoor, Bhopal, Kamran Faisal, Iftikhar, Zainab, Furqan, Muhammad Mohsin, Nighat, Bakhtiar, Jawaid, Masood, Khalique, Abdul, Zil-E-Ali, Ahsan, Rashid, Anam, Dharamshi, Hasnain Abbas, Naqvi, Tahira, Faraz, Ahmad, Anwar, Abdul Wahid, Yaseen, Tahir Muhammad, Shamsi, Ghina Shamim, Shamsi, Ghina, Yaseen, Tahir, Anwer, Wahid, Paredes Decoud, Horacio, Aguilera, Omar, Zelada Alvarez, Ismael Isaac, Marcelo Delgado, Juan, Machain Vega, Gustavo Miguel, Segovia Lohse, Helmut Alfredo, Messa Aguilar, Wendy Leslie, Cabala Chiong, Jose Antonio, Manchego Bautista, Ana Cecilia, Huaman, Eduardo, Zegarra, Sergio, Camacho, Rony, Vergara Celis, Jose Maria, Romani Pozo, Diego Alonso, Hamasaki, Jose, Temoche, Edilberto, Herrera-Matta, Jaime, Garcia Torres, Carla Pierina, Alvarez Barreda, Luis Miguel, Barrionuevo Ojeda, Ronald Renato, Garaycochea, Octavio, Castro Mollo, Melanie, Linares Delgado, Mitchelle Solange De Fa Tima, Fujii, Francisco, Aranzabal Durand, Susana Yrma, Arroyo Basto, Carlos Alejandro, Urbina Rojas, Nelson Manuel, Shu Yip, Sebastian Bernardo, Contreras Vergara, Ana Lucia, Rosas Moran, Andrea Echevarria, Borda Luque, Giuliano, Rodriguez Castro, Manuel, Alvarado Jaramillo, Ramon, Manrique Sila, George, Elizabeth Lopez, Crislee, Zapata Ponze De Leon, Mardelangel, Machaca, Massiell, Coasaca Huaraya, Ronald, Arenas, Andy, Lopez, Crislee, Herrera Puma, Clara Milagros, Pino, Wilfredo, Hinojosa, Christian, Zapata Ponze De Leon, Melanie, Limache, Susan, Manrrique Sila, George, Mercado Rodriguez, Layza-Alejandra, Melo, Renato, Costa-Maia, Jose, Muralha, Nuno, Sauvat, Frederique, Dan, Ionasc, Hogea, Mircea, Eduard, Pandi, Bratu, Razvan-Matei, Beuran, Mircea, Diaconescu, Ionut-Bogdan, Martian, Bogdan-Valeriu, Iordache, Florin-Mihail, Vartic, Mihaela, Vida, Lucian Corneliu, Muntean, Liviu Iuliu, Mironescu, Aurel Sandu, Nsengimana, Vizir Jean Paul, Niragire, Alice, Ingabire, Jean De La Croix Allen, Niyirera, Eugene, Zanini, Nicola, Jovine, Elio, Landolfo, Giovanni, Alomar, Ibrahim N., Alnuqaydan, Saleh A., Altwigry, Abdulrahman M., Othman, Moayad, Osman, Nohad, Alqahtani, Enas, Alzahrani, Mohammed, Alyami, Rifan, Aljohani, Emad, Alhabli, Ibrahim, Mikwar, Zaher, Almuallem, Sultan, Nawawi, Abrar, Bakhaidar, Mohamad, Maghrabi, Ashraf A., Alsaggaf, Mohammed, Aljiffry, Murad, Altaf, Abdulmalik, Khoja, Ahmad, Habeebullah, Alaa, Akeel, Nouf, Ghandora, Nashat, Almoflihi, Abdullah, Huwait, Abdulmalik, Al-shammari, Abeer, Al-Mousa, Mashael, Alghamdi, Masood, Adham, Walid, Albeladi, Bandar, Alfarsi, Muayad Ahmed, Mahdi, Atif, Al Awwad, Saad, Nouh, Thamer, Hassanain, Mazen, Aldhafeeri, Salman, Sadig, Nawal, Algohary, Osama, Aledrisy, Mohannad, Alrifaie, Ahmad, AlRowais, Mohammed, Althwainy, Amani, Shabkah, Alaa, Alamoudi, Uthman, Alrajraji, Mawaddah, Alghamdi, Basim, Aljohani, Saud, Daqeeq, Abdullah, Al-Faifi, Jubran J., Jennings, Vicky, Ngayu, Nyawira, Moore, Rachel, Kong, Victor, Kretzmann, Hayden, Connor, Katie, Nel, Daniel, Sampson, Colleen, Panieri, Eugenio, Sishuba, Nosisa, Tun, Myint, Mphatsoe, Albert Mohale, Carreira, Jo-Anne, Wagener, Mark, Botes, Stefan, Du Plessis, Danelo, Fernandez-Bueno, Fernando, Aguilar-Jimenez, Jose, Andres Garcia-Marin, Jose, Solar Garcia, Lorena, Garcia Florez, Luis Joaquin, Arias Pacheco, Ruben Dario, Pagnozzi, Janet, Jara Quezada, Jimy Harold, Luis Rodicio, Jose, Minguez, German, Rodriguez-Uria, Raquel, Ugalde, Paul, Lopez-Arevalo, Camilo, Barneo, Luis, Gonzales Stuva, Jessica Patricia, Ortega-Vazquez, Irene, Rodriguez, Lorena, Herrera, Norberto, Arachchi, Prasad Pitigala, Senanayake, Wanigasekara Senanayake Mudiyanselage Kithsiri Janakantha, Arachchige, Lalith Asanka Jayasooriya Jayasooriya, Sivaganesh, Sivasuriya, Samaraweera, Dulan Irusha, Thanusan, Vimalakanthan, Musa, Ahmed Elgaili Khalid, Balila, Reem Mohammed Hassan, Mohamed, Mohamed Awad Elkarim Hamad, Ali, Hussein, Elabdin, Hagir Zain, Hassan, Alaa, Mahdi, Sefeldin, Ahmed, Hala, Idris, Sahar Abdoun Ishag, Elsayed, Makki, Elsayed, Mohammed, Mahmoud, Mohamed, Boijsen, Magnus, Lundgren, Per-Olof, Gustafsson, Ulf, Kiasat, Ali, Wogensen, Fredrik, Jurdell, Emma, Thorell, Anders, Thorarinsdottir, Hildur, Utter, Maria, Sundstrom, Sami Martin, Wredberg, Cecilia, Kjellin, Ann, Nyberg, Johanna, Frisk, Bjorn, Sund, Malin, Andersson, Linda, Gunnarsson, Ulf, Ahlqvist, Sandra, Bjorklund, Ida, Royson, Hanna, Weber, Per, Pahlsson, Hans-Ivar, Borin, Eva, Hjertberg, Maria, Schmid, Roger, Schivo, Debora, Despotidis, Vasileios, Breitenstein, Stefan, Staerkle, Ralph F., Schadde, Erik, Deichsel, Fabian, Gerosa, Alexandra, Nocito, Antonio, Raptis, Dimitri Aristotle, Mijuskovic, Barbara, Zuber, Markus, Eisner, Lukas, Kruspi, Swantje, Reinisch, Katharina Beate, Schoewe, Christin, Novak, Allan, Palma, Adrian F., Teufelberger, Gerfried, Kimaro, Msafiri, King, Rachel, Balkan, Ali Zeynel Abidin, Gumar, Mehmet, Yavuz, Mehmet Ali, Karabacak, Ufuk, Lap, Gokhan, Ozkan, Bahar Busra, Karakahya, Murat, Adams, Ryan, Morton, Robert, Henderson, Liam, Gratton, Ruth, Clement, Keiran David, Chang, Kate Yu-Ching, Mcnish, David, Mcintosh, Ryan, Milligan, William, Skelly, Brendan, Anderson-Knight, Hannah, Lawther, Roger, Onimowo, Jemina, Shatkar, Veereanna, Tharmalingam, Shivanee, Woin, Evelina, Fautz, Tessa, Ziff, Oliver, Dindyal, Shiva, Arman, Sam, Talukder, Shagorika, Gadhvi, Vijay, Chew, Luen Shaun, Heath, Jonathan, Blencowe, Natalie, Hallam, Sally, Mannu, Gurdeep Singh, Zachariades, Dimitris-Christos, Snaith, Ailsa Claire, Hettiarachchi, Thusitha Sampath, Nesaratnam, Arjun, Wheeler, James, McCullagh, Darragh, Clements, Joshua Michael, Khan, Ata, Koumpa, Foteini, Neophytou, Christina, Roth, Jessica, Soon, Wai Cheong, Deputy, Mohammed, Ahmed, Ahmed, Ashton, Annelisse, Vincent, Joe, Almy, Jack, Khan, Taufiq, Allen, John Lee Y., Mcintyre, Charlotte Jane, Marshall, Dominic Charles, Sykes, Mark, Behar, Nebil, Jordan, Harriet, Rajjoub, Yaseen, Sherman, Thomas, White, Timothy, Watts, Anna, Ardley, Rohan, Arulampalam, Tan, Shah, Apar, Brown, Damien, Blower, Emma, Sutton, Paul, Gasteratos, Konstantinos, Vimalachandran, Dale, Magee, Cathy, Mcguigan, Andrew, Mcaleer, Stephen, Morgan, Clare, Braungart, Sarah, Lafferty, Kirsten, Labib, Peter, Tanase, Andrei, Mangan, Clodagh, Reza, Lillian, Woodward, Helen, Gouldthorpe, Craig, Turner, Megan, Wild, Jonathan R. L., Malik, Tom A. M., Proctor, Victoria K., Hewage, Kalon, Davies, James, Dubois, Andre, Sarwary, Sayed, Zardab, Ali, Grant, Alan, Mcintyre, Robert, Mogan, Yogendra Praveen, Ho, Weiguang, Chong, Bryon Frankie Hon Khi, Tewari, Shirish, Humm, Gemma, Farinella, Eriberto, Hall, Nigel J., Wright, Naomi J., Major, Christina P., Xerri, Thelma, De Bono, Phoebe, Amin, Jasim, Farhad, Mustafa, Camilleri-Brennan, John F., Robertson, Andrew G. N., Swann, Joanna, Richards, James, Jabbar, Aijaz, Attard, Myranda, Burns, Hannah, Macdonald, Euan, Baldacchino, Matthew, Skehan, Jennifer, Camilleri-Brennan, Julian, Hall, Tom Falconer, Gimzewska, Madelaine, Mclachlan, Greta, Shah, Jamie, Giles, James, Chiu, Selina, Weber, Beatrix, Chiu, Selina Man Yeng, Highcock, Saskia, Hassan, Maleeha, Beasley, William, Vlachogiorgos, Apostolos, Dias, Stephen, Maharaj, Geta, Mcdonald, Rosie, Macdonald, Alisdair, Witherspoon, Paul, Baird, Alan, Sarmah, Panchali, Green, Nikki, Youssef, Haney, Cross, Kate, Rees, Clare M., Van Duren, Bernard, Upchurch, Emma, Khan, Khurram, Abudeeb, Haytham, Hammad, Ahmed, Karandikar, Sharad, Bowley, Doug, Karim, Ahmed, Chachulski, Witold, Richardson, Liam, Dawnay, Giles, Thompson, Ben, Mistry, Ajayesh, Ghetia, Millika, Roy, Sudipta, Al-Obaedi, Ossama, Das, Kaustuv, Prabhudesai, Ash, Cocker, D. M., Tan, Jessica Juliana, Tyler, Robert, Di Franco, Filippo, Ayyar, Shruti, Vivekanantham, Sayinthen, Gokani, Shyam, Gillespie, Michael, Gudlaugsdottir, Katrin, Pezas, Theodore, Currow, Chelise, Kim, Matthew Young-Han, Birring, Amerdip, Edwards, Joanne, Ali, Ased, Das, Suparna, Jha, Madan, Atkinson, Kieran, Luck, Joshua, Fozard, Thomas, Puttick, Michael, Salama, Yahya, Shah, Rohi, Ibrahem, Ahmad Aboelkassem, Ebdewi, Hamdi, Gravante, Gianpiero, El-Rabaa, Saleem, Nnajiuba, Henry, Allott, Rebecca, Bhargava, Aman, Chan, Zoe, Hassan, Zaffar, Makinde, Misty, Hemingway, David, Dean, Ramzana, Boddy, Alexander, Aber, Ahmed, Patel, Vijay, Parakh, Jehangirshaw, Parthiban, Sunil, Ubhi, Harmony Kaur, Hosein, Simon-Peter, Ward, Simon, Malik, Kamran, Jennings, Leifa, Newton, Tom, Alkhouri, Mirna, Kang, Min Kyu, Houlden, Christopher, Barry, Jonathan, Raza, Imtanan, Farquharson, Alistair, Bhattacharya, Sanjeet, Chang, Kate, Wilson, Michael S. J., Neo, Yan Ning, Ibrahim, Ibrahim, Chan, Emily, Peck, Fraser S., Lim, Pei J., North, Alexander S., Blundell, Rebecca, Williamson, Adam, Fouad, Dina, Minocha, Ashish, Mccarthy, Kathryn, Court, Emma, Chambers, Alice, Yee, Jenna, Tham, Ji Chung, Beaton, Ceri, Walsh, Una, Lockey, Joseph, Bokhari, Salman, Howells, Lara, Griffiths, Megan, Yallop, Laura, Singh, Shailinder, Nasher, Omar, Jackson, Paul, Shariffuddin, Abdul Muiz, Ho, Weng Chee, Pabla, Gurpreet, Ramzi, Saed, Zeidan, Shady, Doughty, Jennifer, Sinha, Sidhartha, Davenport, Ross, Lewis, Jason, Duffy, Leo, Mcaleer, Elizabeth, Williams, Eleanor, Som, Robin, Javed, Omar, Boal, Matthew, Harrison, Nicola, Tafazal, Habib, Brogden, Tom, Griffiths, Ewen, Obute, Rhalumi Daniel, Glover, Thomas E., Clark, David J., Boshnaq, Mohamed, Akhtar, Mansoor, Capleton, Pascale, Doughan, Samer, Rabie, Mohamed, Mohamed, Ismail, Samuel, Duncan, Dickson, Lauren, Kennedy, Matthew, Dempster, Eleanor, Brown, Emma, Maple, Natalie, Monaghan, Eimear, Wolf, Bernhard, Garland, Alicia, Mcphee, Arthur, Anderson, David, Anderson, Robert, Hassan, Sarah, Smith, Dave, Lund, Jonathan, Boereboom, Catherine, Murphy, Jennifer, Tierney, Gillian, Tou, Samson, Zimmermann, Eleanor Franziska, Smart, Neil James, Warwick, Andrea Marie, Stasinou, Theodora, Daniels, Ian, Findlay-Cooper, Kim, Mitrasinovic, Stefan, Ray, Swayamjyoti, Varcada, Massimo, D'Souza, Rovan, Omara, Sharif, Spurr, Matthew, Parkinson, Lucienne, Hanks, Anthony, Ma, Jennifer, Abington, Emily, Ramcharn, Meera, Williams, Gethin, Winstanley, Joseph, Kennedy, Ewan D., Yeung, Emily N. W., Jones, Catrin, O'neill, Stephen, Lim, Shujing Jane, Liew, Ignatius, Nair, Hari, Oh, Julia, Koh, Samantha, Wilson, Andrew, Fairfield, Catherine, Anandkumar, Delran, Kirupagaran, Ashok, Jones, Timothy F., Torrance, Hew Dt, Fowler, Alexander J., Chandrakumar, Charmilie, Patel, Priyank, Ashraf, Syed Faaz, Lakhani, Sonam M., Mclean, Aaron Lawson, Basson, Sonia, Batt, Jeremy, Bowman, Catriona, Benons, Natasha, Mason, Clare, Harrison, Rebecca, Quayle, John, Barker, Tom, Summerour, Virginia, Harper, Edward, Smith, Caroline, Hampton, Matthew, Pitt, Sophie K., Ward, Alex E., O'Connor, Timothy, Heywood, Emily G., Chowdhury, Abeed, Hossaini, Sina, Watson, Nicholas Fs, Farah, Ayaan, Chun, Anita, Koh, Hoey, Lim, Grace, Sunderland, Graham, Gould, Laura, Munipalle, P. C., Rooney, H., Browning, D. R. L., Pereira, Bernadette, Nemeth, Kristof, Decker, Emily, Giuliani, Stefano, Shalaby, Aly, Shaikh, Shafaque, Tan, Chern Yan, Palkhi, Ebrahim Y. A., Szczap, Aleksandra, Chidambaram, Swathikan, Chen, Chee Yang, Kulasabanathan, Kavian, Chhabra, Srishti, Kostov, Elisabeth, Harbord, Philippe, Barnacle, James, Palliyil, Madan Mohan, Zikry, Mina, Porter, Johnathan, Raslan, Charef, Hafiz, Shazia, Soltani, Niksa, Baillie, Katie, Singh, Priyanka, Sheth, Shailee, Patel, Kishen, Khalili, Mahry, Choi, Jeesoo, Benger, Matthew, Marples, Lucy, Macfarlane, Alastair, Thurairaja, Ramesh, Boyce, Tamsin, Whewell, Harriet, Jones, Elin, Th'ng, Francesca, Robertson, Nichola, Mirza, Ahmad, Saeed, Haroon, Galloway, Simon, Elena, Gia, Afzal, Mohammad, Zakir, Mohamed, Sodde, Peter, Hand, Charles, Sriram, Aiesha, Clark, Tamsyn, Livesey, Amy, Sinha, Yashashwi, Iqbal, Fahad Mujtaba, Bharj, Indervir Singh, Rotundo, Adriana, Jenvey, Cara, Slade, Robert, Golding, David, Haines, Samuel, Abdullah, Ali Adel Ne'ma, Tilston, Thomas W., Loughran, Dafydd, Donoghue, Danielle, Giacci, Lorenzo, Sherif, Mohamed Ashur, Harrison, Peter, Tang, Alethea, Kotecha, Deevia, Elshaer, Mohamed, Urbonas, Tomas, Riaz, Amjid, Chapman, Annie, Acharya, Parisha, Shalhoub, Joseph, Grossart, Cathleen, McMorran, David, Mlotshwa, Makhosini, Hawkins, William, Loizides, Sofronis, Krishna, Kandaswamy, Orchard, Melanie, Ho, Chik Wai, Thomson, Peter, Khan, Shahab, Taylor, Fiona, Shukla, Jalak, Howie, Emma Elizabeth, Macdonald, K. Linda, Komolafe, Olusegun, Mcintyre, Neil, Cragg, James, Parker, Jody, Stewart, Duncan, Lintin, Luke, Tracy, Julia, Farooq, Tahir, Molina, George, Kaafarani, Haytham, Beyene, Robel, Sava, Jack, Scott, Mark, Swaroop, Mamta, Kennedy, Raelene, Azodo, Ijeoma A., Heffernan, Daithi, Chun, Tristen, Stephen, Andrew, Sion, Melanie, Weinstein, Michael S., Punja, Viren, Bugaev, Nikolay, Goodstein, Monica, Razmdjou, Shadi, Etchill, Eric, Puyana, Juan Carlos, Kesinger, Matthew, Napolitano, Lena, To, Kathleen, Hemmila, Mark, Todd, K. Oliver, Jenner, Edward, Hoogakker, Ellen, Grizhja, Besmir, Ymeri, Shpetim, Galiqi, Gezim, Klappenbach, Roberto, Antezana, Diego, Beleno, Alvaro Enrique Mendoza, Costa, Cecilia, Sanchez, Belen, Aviles, Susan, Fermani, Claudio Gabriel, Villalobos, Santiago, Carmona, Juan Manuel, Hamill, Daniel, Deutschmann, Peter, Sandler, Simone, Cox, Daniel, Nataraja, Ram, Sharpin, Claire, Ljuhar, Damir, Gray, Demi, Haines, Morgan, Iyer, Dush, Niranjan, Nithya, D'Amours, Scott, Ashtari, Morvarid, Franco, Helena, Karim, Sabbir, Aman, Nowrin F., Estee, Mahnuma Mahfuz, Salma, Umme, Razzaque, Joyeta, Kanta, Tasnia Hamid, Tori, Sayeeda Aktar, Alamin, Shadid, Roy, Swapnil, Al Amin, Shadid, Karim, Rezaul, Haque, Muhtarima, Faruq, Amreen, Iftekhar, Farhana, O'Shea, Margaret, Padmore, Greg, Jonnalagadda, Ramesh, Litvin, Andrey, Filatau, Aliaksandr, Paulouski, Dzmitry, Shubianok, Maryna, Shachykava, Tatsiana, Khokha, Dzianis, Khokha, Vladimir, Djivoh, Fernande, Dossou, Francis, Seto, Djifid Morel, Gbessi, Dansou Gaspard, Noukpozounkou, Bruno, Keke, Kpemahouton Rene, Hodonou, Fred, Ahounou, Ernest Yemalin Stephane, Alihonou, Thierry, Denakpo, Max, Ahlonsou, Germain, Bedada, Alemayehu Ginbo, Nsengiyumva, Carlos, Kwizera, Sandrine, Barendegere, Venerand, Choi, Philip, Jamal, Luai, Chen, Tzu-Ling, Yip, Chingwan, Zapata, Felipe, Lanau, Maria Isabel Villegas, Arango, Maria Clara Mendoza, Restrepo, Ivan Mendoza, Giraldo, Ruben Santiago Restrepo, Youssef, Mohamed, Thabet, Waleed, Sanad, Aly, Zaki, Ahmed, Abdel-Hameed, Noran, Mostafa, Mohamed, Omar, Muhammad Fathi Waleed, Ghanem, Ahmed, Denewar, Adel, Emara, Eman, Rashad, Eman, Sakr, Ahmad, Elashry, Rehab, Emile, Sameh, Khafagy, Toqa, Elhamouly, Sara, Elfarargy, Arwa, Mohamed, Amna Mamdouh, Nagy, Ghada Saied, Esam, Abeer, Elwy, Eman, Hammad, Aya, Khallaf, Salwa, Ibrahim, Eman, Saidbadr, Ahmed, Moustafa, Ahmed, EldosoukyMohammed, Amany, Elgheriany, Mohammed, Abdelmageed, Eman, Al Raouf, Eman Abd, Elbanby, Esraa Samir, Elmasry, Maha, Farahat, Mahitab Morsy, Mansor, Eman Yahya, Hegazy, Eman Magdy, Gamal, Esraa, Gamal, Heba, Kandil, Hend, Abdelrouf, Doaa Maher, Moaty, Mohamed, Gamal, Dina, El-Sagheer, Nada, Salah, Mohamed, Magdy, Salma, Salah, Asmaa, Essam, Ahmed, Ali, Ahmed, Badawy, Mahmoud, Ahmed, Sara, Mohamed, Mazed, Assal, Abdelrahman, Sleem, Mohamed, Ebidy, Mai, Elrazek, Aly Abd, Zahran, Diaaaldin, Adam, Nourhan, Nazir, Mohamed, Hassanein, Adel B., Ismail, Ahmed, Elsawy, Amira, Mamdouh, Rana, Mabrouk, Mohamed, Ahmed, Lopna Ahmed Mohamed, Alnaby, Mohamed Hassab, Magdy, Eman, Abd-Elmawla, Manar, Fahim, Marwan, Mowafy, Bassant, Mahmoud, Moustafa Ibrahim, Allam, Meran, Alkelani, Muhammad, El Gendy, Noran Halim, Aboul-Naga, Mariam Saad, El-Din, Reham Alaa, Elgendy, Alyaa Halim, Ismail, Mohamed, Shalaby, Mahmoud, Elsharkawy, Aya Adel, Moghazy, Mahmoud Elsayed, Elbisomy, Khaled Hesham, Shakshouk, Hend Adel Gawad, Hamed, Mohamed Fouad, Ebidy, Mai Mohamed, Ahmed, Hayam, Adel, Israa, Omar, Mohammad Elsayed, Ibrahim, Mohamed, Ghoneim, Omar, Hesham, Omar, Gamal, Shimaa, Hilal, Karim, Arafa, Omar, Awad, Sawsan Adel, Salem, Menatalla, Elsherif, Fawzia Abdellatif, Elsabbagh, Nourhan, Aboelsoud, Moustafa R., Rida, Ahmed Hossam Eldin Fouad, Hossameldin, Amr, Hany, Ethar, Asar, Yomna Hosny, Anwar, Nourhan, Gadelkarim, Mohamed, Abdelhady, Samar, Morshedy, Eman Mohamed, Saad, Reham, Soliman, Nourhan, Salama, Mahmoud, Ezzat, Eslam, Mohamed, Arwa, Ibrahim, Arwa, Fergany, Alaa, Mohammed, Sara, Reda, Aya, Allam, Yomna, Saad, Hanan Adel, Abdelfatah, Afnan, Fathy, Aya Mohamed, El-Sehily, Ahmed, Kasem, Esraa Abdalmageed, Hassan, Ahmed Tarek Abdelbaset, Mohammed, Ahmed Rabeih, Saad, Abdalla Gamal, Ibrahim, Arij, Hassaan, Amr, Mohammed, Mohammed Mustafa, Elhoseny, Ghada, Magdy, Mohamed, Elkhalek, Esraa Abd, Zakaria, Yehia, Ezzat, Tarek, El Dahab, Ali Abo, Kelany, Mohamed, Arafa, Sara, Hassan, Osama Mokhtar Mohamed, Badwi, Nermin Mohamed, Sleem, Ahmad Saber, Ahmed, Hussien, Abdelbadeai, Kholoud, Abdullah, Mohamed Abozed, Lokman, Muhammad Amsyar Auni, Bahar, Suraya, Abdelazeam, Anan Rady, Adelshone, Abdelrahman, Bin Hasnan, Muhammad, Zulkifli, Athirah, Kamarulzamil, Siti Nur Alia, Elhendawy, Abdelaziz, Latif, Aliang, Bin Adnan, Ahmad, Shaharuddin, Shahadatul, Majid, Aminah Hanum Haji Abdul, Al-Marakby, Dina, Bin Ismail, Mohamad Jeffrey, Basir, Elissa Rifhan Mohd, Ali, Citra Dewi Mohd, Ata, Aya Yehia, Nasr, Maha, Rezq, Asmaa, Sheta, Ahmed, Tariq, Sherif, Sallam, Abd Elkhalek, Darwish, Abdelrhman K. Z., Elmihy, Sohaila, Elhadry, Shady, Farag, Ahmed, Hajeh, Haidar, Abdelaal, Abdelaziz, Aglan, Amro, Zohair, Ahmed, Essam, Mahitab, Moussa, Omar, El-Gizawy, Esraa, Samy, Mostafa, Ali, Safia, Elhalawany, Esraa, Ata, Ahmed, El Halawany, Mohamed, Nashat, Mohamed, Soliman, Samar, Elazab, Alaa, Samy, Mostada, Abdelaziz, Mohamed A., Ibrahim, Khaled, Ibrahim, Ahmed mohamed, Gado, Ammar, Eldeen, Esraa Alm, loaloa, Mohamed Reda, Abouzaid, Arwa, Eldin, Mostafa Ahmed Bahaa, Hashad, Eman, Sroor, Fathy, Gamil, Doaa, Abdulhakeem, Eman Mahmoud, Zakaria, Mahmoud, Mohamed, Fawzy, Abubakr, Marwan, Ali, Elsayed, Magdy, Hesham, Refaat, Ahmed, Ramadan, Menna Tallah, Mohamed, Mohamed Abdelaty, Mansour, Salma, Amin, Hager Abdul Aziz, Mohamed, Ahmed Rabie, Saami, Mahmoud, Elsayed, Nada Ahmed Reda, Tarek, Adham, Mahmoud, Sabry Mohy Eldeen, El Sayed, Islam Magdy, Reda, Amira, Shawky, Martina Yusuf, Salem, Mohammed Mousa, El-Din, Shahinaz Alaa, Soliman, Noha Abdullah, Talaat, Muhammed, Alaael-Dein, Shahinaz, Elhusseiny, Ahmed Abd Elmoen, Abdullah, Noha, Elshaar, Mohammed, Ibraheem, Aya Abdel Fatah, Abdulaziz, Hager, Ismail, Mohammed Kamal, Madkor, Mona Hamdy, Abdelaty, Mohamed, Abdel-Kader, Sara Mahmoud, Salah, Osama Mohamed, Eldafrawy, Mahmoud, Eldeeb, Ahmed Zaki, Eid, Mostafa Mahmoud, Attia, Attia, Shwky, Ayman, Badenjki, Mohamed Adel, Soliman, Abdelrahman, Al Attar, Samaa Mahmoud, Sayed, Farrag, Sabour, Fahd Abdel, Azizeldine, Mohammed G., Shawqi, Muhammad, Hashim, Abdullah, Aamer, Ahmed, Abdelraouf, Ahmed Mahmoud, Abdelshakour, Mahmoud, Ibrahim, Amal, Mahmoud, Basma, Mahmoud, Mohamed Ali, Qenawy, Mostafa, Rashed, Ahmed M., Dahy, Ahmed, Sayed, Marwa, Shamsedine, Ahmed W., Mohamed, Bakeer, Hasan, Ahmad, Saad, Mahmoud M., Bassit, Khalil Abdul, El-Latif, Nadia KhalidAbd, Elzahed, Nada, El Kashash, Ahmed, Bekhet, Nada Mohamed, Hafez, Sarah, Gad, Ahmed, Maher, Mahmoud Elkhadragy, Elsameea, Ahmed Abd, Hafez, Mohamed, Sabe, Ahmad, Ahmed, Ataa, Shahine, Ahmed, Dawood, Khaled, Gaafar, Shireen, Husseiny, Reem, Aboelmagd, Omnia, Soliman, Ahmed, Mesbah, Nourhan, Emadeldin, Hossam, Al Meligy, Amgad, Bekhet, Amira Hassan, Hasan, Doaa, Alhady, Khaled, Sabe, Ahmad Khaled, Elnajjar, Mahmoud A., Aboelella, Majed, Hamsho, Ward, Hassan, Ihab, Saad, Hala, Abdelazim, Galaleldin, Mahmoud, Hend, Wael, Noha, Kandil, Ahmedali M., Magdy, Ahmed, Elkholy, Shimaa Said, Adel, Badr Eldin, Dabbour, Kareem, Elsherbiney, Saged, Mattar, Omar, Abdrabou, Abdulshafi Khaled, Aly, Mohammed Yahia Mohamed, Geuoshy, Abdelrahman, Elnagar, Ahmedglal, Ahmed, Saraibrahim, Abdelmotaleb, Ibrahem, Saleh, Amr Ahmed, Saeed, Manar, Mahmoud, Shady, Tawfik, Badreldin Adel, Ismail, Samar Adel, Zakaria, Esraay, Gad, Mariam O., Elhelbawy, Mohamed Salah, Bassem, Monica, Maraie, Noha, Elhadary, Nourhan Medhat, Semeda, Nourhan, Mohamed, Shaza Rabie, Bakry, Hesham Mohammed, Essam, A. A., Tarek, Dina, Ashour, Khlood, Elhadad, Alaa, Abdel-Aty, Abdulrahman, Rakha, Ibrahim, Matter, Sara Mamdouh, Abdelhamed, Rasha, Abdelkader, Omar, Hassaan, Ayat, Soliman, Yasmin, Mohamed, Amna, Farouk, Sara Amr Mohamed, Ibrahim, Eman Mohamed, El-Taher, Esraa, Mostafa, Merna, Badr, Mohamed Fawzy Mahrous, Elsemelawy, Rofida, El-Sawy, Aya, Bakr, Ahmad, Al Rafati, Ahmad Abdel Razaq, Saar, Sten, Reinsoo, Arvo, Seyoum, Nebyou, Worku, Tewodros, Fitsum, Agazi, Tolonen, Matti, Parmentier, Benoit, Dardenne, Sabrina, Robert, Elsa, Maillot, Betty, Courboin, Etienne, Hascoet, Juliette, Kaci, Amir Ait, Prudhomme, Thomas, Ballouhey, Quentin, Grosos, Celine, Fourcade, Laurent, Cecilia, Tolg, Jean-Francois, Colombani, Helene, Francois-Coridon, Delforge, Xavier, Haraux, Elodie, Dousset, Bertrand, Schiavone, Roberto, Gaujoux, Sebastien, Marret, Jean-Baptiste, Haffreingue, Aurore, Rod, Julien, Renaux-Petel, Mariette, Lecompte, Jean-Francois, Breaud, Jean, Gastaldi, Pauline, Taieb, Chouikh, Claire, Raquillet, Anis, Echaieb, Bustangi, Nasir, Lopez, Manuel, Grella, Maria Giovanna, Mariani, Aurora, Broch, Aline, Bandoh, Dickson, Kyereh, Martin, Asumah, Hamza, Appiah, Eric Kofi, Wondoh, Paul, Gyedu, Adam, Dally, Charles, Agbedinu, Kwabena, Amoah, Michael, Yifieyeh, Abiboye, Amoako-Boateng, Mabel, Dayie, Makafui, Hagan, Richmond, Debrah, Sam, Ohene-Yeboah, Micheal, Clegg-Lampety, Joe-Nat, Etwire, Victor, Dakubo, Jonathan, Essoun, Samuel, Bonney, William, Glover-Addy, Hope, Osei-Nketiah, Samuel, Amoako, Joachim, Adu-Aryee, Niiarmah, Appeadu-Mensah, William, Bediako-Bowan, Antoinette, Dedey, Florence, Ekow, Mattew, Akatibo, Emmanuel, Yakubu, Musah, Kordorwu, Hope Edem Kofi, Asare-Bediako, Kwasi, Tackie, Enoch, Aaniana, Kenneth, Acquah, Emmanuel, Opoku-Agyeman, Richard, Avoka, Anthony, Kusi, Kwasi, Maison, Kwame, Gyamfi, Frank Enoch, Barnabas, Gandau Naa, Abdul-Latif, Saiba, Amoako, Philip Taah, Davor, Anthony, Dassah, Victor, Dagoe, Enoch, Kwakyeafriyie, Prince, Akoto, Elliot, Ackom, Eric, Mensah, Ekow, Atkins, Ebenezer Takyi, Coompson, Christian Lari, Ivros, Nikolaos, Ferousis, Christoforos, Kalles, Vasileios, Kyriazanos, Ioannis, Barkolias, Christos, Tselos, Angelos, Tzikos, Georgios, Voulgaris, Evangelos, Bamicha, Athanasia, Stefanopoulos, Anastasios, Patoulias, Ioannis, Sfougaris, Dimitrios, Valioulis, Ioannis, Balalis, Dimitrios, Korkolis, Dimitrios, Manatakis, Dimitrios K., Kyrou, Georgios, Karabelias, Georgios, Papaskarlatos, Iason-Antonios, Konstantina, Kolonia, Zampitis, Nikolaos, Papailia, Aspasia, Theodosopoulos, Theodosios, Gkiokas, Georgios, Mitroudi, Magdalini, Panteli, Christina, Feidantsis, Thomas, Farmakis, Konstantinos, Kyziridis, Dimitrios, Ioannidis, Orestis, Parpoudi, Styliani, Parasyris, Stavros, Margaritis, Michail, Aguilera-Arevalo, Maria-Lorena, Coyoy-Gaitan, Otto, Rosales, Javier, Tale, Luis, Barrios, Emmanuel, Rodriguez, Servio Tulio Torres, Galvez, Carlos Paz, Cruz, Danilo Herrera, Rosenberg, Guillermo Sanchez, Matheu, Alejandro, Cohen, David Monterroso, Paul, Marie, Charles, Angeline, Lam, Justin Chak Yiu, Yeung, Man Hon Andrew, Fok, Chi Ying Jacquelyn, Li, Ka Hin Gabriel, Lai, Anthony Chuk-Him, Cheung, Yuk Hong Eric, Wong, Hong Yee, Leung, Ka Wai, Lee, Tien Seng Bryan, Lam, Wai Him, Dao, Weihei, Kwok, Stephanie Hiu-wai, Chan, Tsz-Yan Katie, Ng, Yung Kok, Mak, T. W. C., Foo, Chi Chung, Yang, James, Bhatnagar, Ankur, Upadhyaya, Vijaid, Muddebihal, Uday, Dar, Wasim, Janardha, K. C., Aruldas, Neerav, Adella, Fidelis Jacklyn, Rulie, Anthonius Santoso, Iskandar, Ferdy, Setiawan, Jonny, Evajelista, Cicilia Viany, Natalie, Hani, Suyadi, Arlindawati, Gunawan, Rudy, Karismaningtyas, Herlin, Mata, Lusi Padma Sulistianingsih, Andika, Ferry Fitriya Ayu, Hasanah, Afifatun, Widiastini, T. Ariani, Purwaningsih, Nurlaila Ayu, Mukin, Annisa Dewi Fitriana, Rahmah, Dina Faizatur, Nurqistan, Hazmi Dwinanda, Arsyad, Hasbi Maulana, Adhitama, Novia, Jeo, Wifanto Saditya, Sutandi, Nathania, Clarissa, Audrey, Gultom, Phebe Anggita, Billy, Matthew, Haloho, Andreass, Johanna, Nadya, Lee, Felix, Dorani, Radin Mohd Nurrahman Radin, Glynn, Martha, Alherz, Mohammad, Goh, Wennweoi, Shiwani, Haaris A., Sproule, Lorraine, Conlon, Kevin C., Bala, Miklosh, Kedar, Asaf, Bianco, Federica, Steccanella, Francesca, Gallo, Gaetano, Trompetto, Mario, Clerico, Giuseppe, Papandrea, Matteo, Sammarco, Giuseppe, Sacco, Rosario, Giavarini, Luisa, Giglio, Mariano Cesare, Bucci, Luigi, Pagano, Gianluca, Sollazzo, Viviana, Peltrini, Roberto, Luglio, Gaetano, Birindelli, Arianna, Mingrone, Pietro, Selvaggi, Francesco, Selvaggi, Lucio, Pellino, Gianluca, Di Martino, Natale, Curletti, Gianluca, Aonzo, Paolo, Galleano, Raffaele, Berti, Stefano, Francone, Elisa, Boni, Silvia, Lorenzon, Laura, lo Conte, Annalisa, Balducci, Genoveffa, Confalonieri, Gianmaria, Pesenti, Giovanni, Gavagna, Laura, Vasquez, Giorgio, Targa, Simone, Occhionorelli, Savino, Andreotti, Dario, Armellini, Andrea, Chiesa, Deborah, Aquilino, Fabrizio, Chetta, Nicola, Picciariello, Arcangelo, Abdelkhalek, Mohamed, Belli, Andrea, De Franciscis, Silvia, Bigaran, Annamaria, Favero, Alessandro, Basso, Stefano M. M., Salusso, Paola, Perino, Martina, Mochet, Sylvie, Sasia, Diego, Riente, Francesco, Migliore, Marco, Basilico, Silvia, Corbellini, Carlo, Lazzari, Veronica, Angelieri, Daniele, Coletta, Diego, Falaschi, Federica, Catani, Marco, Reali, Claudia, Malavenda, Mariastella, Del Basso, Celeste, Ribaldi, Sergio, Coletti, Massimo, Natili, Andrea, Depalma, Norma, Iannone, Immacolata, Antoniozzi, Angelo, Rossi, Davide, Gui, Daniele, Perrotta, Gerardo, Ripa, Matteo, Giardino, Francesco Ruben, Foco, Maurizio, Vicario, Erika, Nita, Gabriela Elisa, Leone, Nicoletta, Simioni, Andrea, De Boni, Davide, Pasquali, Sandro, Goldin, Elena, Vendramin, Elena, Ciccioli, Eleonora, Tedeschi, Umberto, Violi, Paola, Campagnaro, Tommaso, Conci, Simone, Lazzari, Giovanni, Iacono, Calogero, Gulielmi, Alfredo, Manfreda, Serena, Rinaldi, Anna, Ringressi, Maria Novella, Brunoni, Beatrice, Salamone, Giuseppe, Mangiapane, Mirko, De Marco, Paolino, La Brocca, Antonella, Tutino, Roberta, Silvestri, Vania, Licari, Leo, Fontana, Tommaso, Falco, Nicolo, Cocorullo, Gianfranco, Shalaby, Mostafa, Sileri, Pierpaolo, Arcudi, Claudio, Bsisu, Isam, Aljboor, Khaled, Abusalem, Lana, Alnusairat, Aseel, Qaissieh, Ahmad, Al-Dakka, Emad, Ababneh, Ali, Halhouli, Oday, Yusufali, Taha, Mohammed, Hussein, Lando, Justus, Parker, Robert, Ndegwa, Wairimu, Gribauskaite, Jolanta, Kuliavas, Justas, Dulskas, Audrius, Samalavicius, Narimantas E., Jasaitis, Kristijonas, Parseliunas, Audrius, Nevieraite, Viktorija, Slapelyte, Evelina, Dainius, Edvinas, Subocius, Andrejus, Venclauskas, Linas, Gulbinas, Antanas, Kasputyte, Simona, Mikuckyte, Deimante, Kiudelis, Mindaugas, Jankus, Tomas, Petrikenas, Steponas, Pazuskis, Matas, Vilcinskas, Mantas, Banaitis, Vincas Jonas, Gaizauskas, Vytautas, Grisin, Edvard, Mazrimas, Povilas, Drungilas, Mantas, Lagunavicius, Karolis, Lipnickas, Vytautas, Majauskyte, Dovile, Abaliksta, Tomas, Uscinas, Laimonas, Simutis, Gintaras, Ladukas, Adomas, Danys, Donatas, Sruogiene, Elena Zdanyte, Visinskas, Petras, Dragatas, Deividas, Burmistrovas, Andrius, Tverskis, Zygimantas, Vaicius, Arturas, Mazelyte, Ruta, Zadoroznas, Antanas, Ziubryte, Greta, Rahantasoa, Finaritra Casimir Fleur Prudence, Samison, Luc Herve, Rasoaherinomenjanahary, Fanjandrainy, Tolotra, Todisoa Emmanuella Christina, Mukuzunga, Cornelius, Kwatiwani, Chimwemwe, Msiska, Nelson, Chai, Feng Yih, Asilah, Siti Mohd Desa, Syibrah, Khuzaimah Zahid, Chin, Pui Xin, Riswan, Nur Zulaika, Chong, Hoong-Yin, Aziz, Nora Abdul, Poh, Keat-Seong, Chai, Chu-Ann, Kumar, Sandip, Taher, Mustafa Mohammed, Aziz, Dayang Nita Abdul, Julaihi, Rokayah, Jethwani, Durvesh Lacthman, Yahaya, Muhammad Taqiyuddin, Mathew, Susan Wndy, Chung, Kuet Jun, Nirumal, Milaksh Kumar, Tze, R. Goh Ern, Ali, Syed Abdul Wahhab Eusoffee Wan, Gan, Yiing Yee, Ting, Jesse Ron Swire, Sii, Samuel S. Y., Koay, Kean Leong, Tan, Yi Koon, Cheah, Alvin Ee Zhiun, Wong, Chui Yee, Mat, Tuan Nur'Azmah Tuan, Chow, Crystal Yern Nee, Har, Prisca A. L., Der, Yishan, Henry, Fitjerald, Low, Xinwei, Neo, Ya Theng, Heng, Hian Ee, Kong, Shu Ning, Gan, Cheewei, Mok, Yi Ting, Tan, Yee Wen, Palayan, Kandasami, Tata, Mahadevan Deva, Cheong, Yih Jeng, Gunaseelan, Kuhaendran, Nasir, Wan Nurul'Ain Wan Mohd, Yoganathan, Pigeneswaren, Lee, Eu Xian, Saw, Jian Er, Yeang, Li Jing, Koh, Pei Ying, Lim, Shyang Yee, Teo, Shuang Yi, Grech, Nicole, Magri, Daniela, Cassar, Kristina, Mizzi, Christine, Falzon, Malcolm, Shaikh, Nihaal, Scicluna, Ruth, Zammit, Stefan, Mizzi, Sean, Brincat, Svetlana Doris, Tembo, Thelma, Le, Vu Thanh Hien, Grima, Tara, Sammut, Keith, Carabott, Kurt, Zarb, Ciskje, Navarro, Andre, Dimech, Thea, Camilleri, Georgette Marie, Bertuello, Isaac, Dalli, Jeffrey, Bonavia, Karl, Corro-Diaz, Samantha, Manriquez-Reyes, Marisol, la Medina, Antonio Ramos-De, Abdelhamid, Amina, Hrora, Abdelmalek, Benammi, Sarah, Bachri, Houda, Abbouch, Meryem, Boukhal, Khaoula, Bennai, Redouane Mammar, Belkouchi, Abdelkader, Jabal, Mohamed Sobhi, Benyaiche, Chaymae, Vermaas, Maarten, Duinhouwer, Lucia, Pastora, Javier, Wood, Greta, Merlo, Maria Soledad, Ajao, Akinlabi, Ayandipo, Omobolaji, Lawal, Taiwo, Abdurrazzaaq, Abdussemiu, Alada, Muslimat, Nasir, Abdulrasheed, Habeeb, Olufemi, Mendel, Henry, Bello, Bashir, Muktar, Umar, Olajide, Thomas Olagboyega, Oshati, Oyindamola, Ihediwa, George, Adenekan, Babajide, Nwinee, Victor, Lawal, Abdulrazzaq, Bode, Chris, Olugbemi, Mojolaoluwa, Odutola, Oluwatomi, Adebola, Oluwaseyi, Onuoha, Clement, Balogun, Fatai, Ajai, Olalekan, Njokanma, Iloba, Kache, Stephen, Ajah, Jonathan, Makama, Jerry, Adamu, Ahmed, Baba, Suleiman, Aliyu, Mohammad, Aliyu, Shamsudeen, Ukwenya, Yahaya, Aliyu, Halima, Sholadoye, Tunde, Daniyan, Muhammad, Ogunsua, Oluseyi, Sheshe, Abdurrahaman, Mshelbwala, Philip, Samson, Garba, Timothy, Oyediran Kehinde, Samuel, Sani Ali, Ajiboye, Anthony, Amole, Isaac, Abiola, Olajide, Olaolorun, Akin, Veen, Torhild, Kanani, Arezo, Styles, Kristian, Herikstad, Ragnar, Larsen, Johannes Wiik, Soreide, Jon Arne, Jensen, Elisabeth, Gran, Mads, Aahlin, Eirik Kjus, Gaarder, Tina, Monrad-Hansen, Peter Wiel, Naess, Pal Aksel, Lauzikas, Giedrius, Wiborg, Joachim, Holte, Silje, Augestad, Knut Magne, Banipal, Gurpreet Singh, Moe, Thomas Tetens, Schultz, Johannes Kurt, Al-taher, Taher, Hamdan, Ayah, Salman, Ayman, Saadeh, Rana, Musleh, Aseel, Jaradat, Dana, Abushamleh, Soha, Hanoun, Sakhaa, Abu Qumbos, Amjad, Hamarshi, Aseel, Taher, Ayman, Qawasmi, Israa, Qurie, Khalid, Altarayra, Marwa, Ghannam, Mohammad, Shaheen, Alaa, Herebat, Azher, Abdelhaq, Aram, Shalabi, Ahmad, Abu-toyour, Maram, Asi, Fatema, Shamasneh, Ala, Atiyeh, Anwar, Mustafa, Mousa, Zaa'treh, Rula, Dabboor, Majd, Alaloul, Enas, Baraka, Heba, Meqbil, Jehad, Al-Buhaisi, Alaa, Elshami, Mohamedraed, Afana, Samah, Jaber, Sahar, Alyacoubi, Said, Abuowda, Yousef, Idress, Tasneem, Abuqwaider, Eman, Al-saqqa, Sara, Bowabsak, Alaa, El Jamassi, Alaa, Hasanain, Doaa, Al-farram, Hadeel, Salah, Maram, Firwana, Aya, Hamdan, Marwa, Awad, Israa, Ashour, Ahmad, Al Barrawi, Fayez Elian, Al-khatib, Ahmed, Al-faqawi, Maha, Fares, Mohamed, Elmashala, Amjad, Adawi, Mohammad, Adawi, Ihdaa, Khreishi, Reem, Khreishi, Rose, Ghaben, Ahed, Nadeem, Najwa, Saqlain, Muhammad, Abbasy, Jibran, Alvi, Abdul Rehman, Shahzad, Noman, Butt, Muhammad Talha, Razi, Syed Asaat ul, Ahmed, Asdaq, Niazi, Ali Khan, Raza, Ibrahim, Baluch, Fatima, Raza, Ahmed, Bani-Sadar, Ahmad, Adil, Muhammad, Raza, Awais, Javaid, Mahnoor, Waqar, Muhammad, Khan, Maryam Ali, Arshad, Mohammad Mohsin, Amjad, Mohammadasim, Torres Cardozo, Jorge, O'Higgins Roche, Marcelo, Pertersen Servin, Gustavo Rodolfo, Paez Lopez, Larissa Ines, Melo Cardozo, Ramon Augusto, Espinoza, Fernando, Perez Rojas, Angel David, Sanchez, Diana, Sanchez Samaniego, Camila, Guevara Torres, Shalon, Canta Calua, Alexander, Razuri, Cesar, Ortiz, Nadia, Rodriguez, Xianelle, Carrasco, Nahilia, Saravia, Fridiz, Shibao Miyasato, Hector, Valcarcel-Saldana, Maria, Alejos Bermudez, Ysabel Esthefany, 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N., Sanni, Hakeem Ayomi, Okenabirhie, Ogheneochuko, Homeida, Anmar, Younis, Abobaker, Omer, Omer Abdelbagi, Abdulaziz, Mustafa, Mussad, Ali, Adam, Ali, Sokratous, Arestis, Breistrand, Michaela, Sigurdadottir, Johanna, Nikberg, Maziar, Chabok, Abbas, Elbe, Peter, Saraste, Deborah, Rutkowski, Wiktor, Forlin, Louise, Niska, Karoliina, Oswald, Dennis, Peros, Georgios, Bluelle, Rafael, Reinisch, Katharina, Frey, Daniel, Palma, Adrian, Zumbuhl, Lucius, Werder, Gabriela, Mahanty, Silke, Widmer, Lukas Werner, Muller, Julia, Gubeli, Alissa, Zuk, Grzegorz, Gulcicek, Osman Bilgin, Vartanoglu, Talar, Kose, Emin, Karahan, Servet Rustu, Aydin, Mehmet Can, Sahbaz, Nuri Alper, Halicioglu, Ilkay, Alis, Halil, Sapci, Ipek, Aiyaman, Can, Pektas, Ahmet Murat, Cengiz, Turgut Bora, Tansoker, Ilkan, Isler, Vedatcan, Cevik, Muazzez, Mutlu, Deniz, Ozben, Volkan, Ozmen, Berk Baris, Bayram, Sefa, Yolcu, Sinem, Kobal, Berna Buse, Toto, Omer Faruk, Cakaloglu, Haluk Cem, Karabulut, Kagan, Mutlu, Vahit, Celik, Saban, Semiz, Anil, Bodur, Selim, Gul, Enisburak, Murutoglu, Busra, Yildirim, Reyyan, Baki, Bahadir Emre, Arslan, Ekin, Guner, Ali, Tomas, Kadir, Walker, Nathan, Shrimanker, Nikhita, Cole, Simon, Breslin, Ryan, Srinivasan, Ravi, Hunter, Kristina, Al-Bahrani, Ahmed, Mairs, Nora Grace, Rocke, Alistair, Dick, Lachlan, Qureshi, Mobeen, Chowdhury, Debkumar, Wright, Naomi, Skerritt, Clare, Kufeji, Dorothy, Ho, Adrienne, Dissanayake, Tharindra, Tennakoon, Athula, Ali, Wadah, Tan, Charlene, O'Neill, Stephen, Knight, Stephen, Nassif, Dima, Sharma, Abhishek, White, Rebecca, Mehdi, Aia, Post, Nathan, Kalakouti, Eliana, Dashnyam, Enkhbat, Stourton, Frederick, Mykoniatis, Ioannis, Wong, Francisca, Gupta, Ashish, Shatkar, Veeranna, Kadiwar, Suraj, Smedley, Alexander, Wakefield, Rebecca, Herrod, Philip, Blackwell, James, Cohen, Fraser, Bandi, Ashwath, Bond-Smith, Giles, Farhangmehr, Neda, Perenyei, Miklos, Ireland, Philip, Bowling, Kirk, Bunting, David, Longstaff, Lydia, Keogh, Kenneth, Jeon, Hyunjin, Iqbal, Muhammad Rafaih, Khosla, Shivun, Jeffery, Anna, Perera, James, Alhammali, Tariq, Oram, Shaun, Kidd, Thomas, Cullen, Fraser, Owen, Christopher, Wilson, Michael, Chiu, Seehui, Sarafilovic, Hannah, Ploski, Jennifer, Evans, Elizabeth, Abbas, Athar, Kamya, Sylvia, Ishak, Norzawani, Bisset, Carly, Andress, Cedar, Chin, Ye Ru, Patel, Priya, Evans, David, Haslegrave, Aidan, Boggon, Adam, Laurie, Kirsten, Mann, Thomas, Mansuri, Anahita, Davies, Rachel, Shahbaz, Aized Raza, Eng, Calvin, Din, Farhat, L'Heveder, Ariadne, Park, Esther H. 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Zilinskas, J, Roslani, Ac, Goh, Cc, Irwin, G, Luque, L, Shiwani, H, Altamimi, A, Alsaggaf, Mu, Jeyakumar, J, Cengiz, Y, Raptis, Da, Glasbey, Jc, Modolo, Mm, Iyer, D, King, S, Arthur, T, Nahar, Sn, Waterman, A, Walsh, M, Agarwal, A, Zani, A, Firdouse, M, Rouse, T, Liu, Qy, Correa, Jc, Talving, P, Worku, M, Arnaud, A, Kalles, V, Kumar, B, Kumar, S, Quek, R, Ansaloni, L, Altibi, A, Venskutonis, D, Whitaker, J, Msosa, V, Tew, Yy, Farrugia, A, Borg, E, Bentounsi, Z, Gala, T, Al-Slaibi, I, Tahboub, H, Alser, Oh, Romani, D, Major, P, Mironescu, A, Bratu, M, Kourdouli, A, Ndajiwo, A, Altwijri, A, Gudal, A, Jubran, A, Seisay, S, Lieske, B, Ortega, I, Senanayake, Kj, Abdulbagi, O, Raptis, D, Altinel, Y, Kong, C, Teasdale, E, Stoddart, M, Kabariti, R, Suresh, S, Gash, K, Narayanan, R, Maimbo, M, Fermani, C, Balmaceda, R, Macdermid, E, Chenn, R, Yong, Co, Edye, M, Jarmin, M, D'Amours, Sk, Youssef, D, Phillips, N, Brown, J, George, R, Koh, C, Warren, O, Hanley, I, Dickfos, M, Nawara, C, Ofner, D, 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Z., Višinskas, P., Žilinskienė, R., Dragatas, D., Burmistrovas, A., Tverskis, Z., Vaicius, A., Mazelyte, R., Zadoroznas, A., Žiubrytė, G., Rahantasoa, F. C. F. P., Samison, L. H., Rasoaherinomenjanahary, F., Tolotra, T. E. C., Mukuzunga, C., Kwatiwani, C., Msiska, N., Chai, F. Y., Asilah, S. M. D., Syibrah, K. Z., Chin, P. X., Riswan, N. Z., Aziz, N. A., Poh, K. S., Chai, C. A., Taher, M. M., Aziz, D. N. A., Julaihi, R., Jethwani, D. L., Yahaya, M. T., Mathew, S. W., Chung, K. J., Nirumal, M. K., Ali, Sawew., Gan, Y. Y., Ting, J. R. S., Sii, S. S. Y., Koay, K. L., Tan, Y. K., Cheah, A. E. Z., Wong, C. Y., Nur'Azmah Tuan Mat, T., Chow, C. Y. N., Har, P. A. L., Der, Y., Henry, F., Low, X., Neo, Y. T., Heng, H. E., Kong, S. N., Gan, C., Mok, Y. T., Tan, Y. W., Palayan, K., Tata, M. D., Cheong, Y. J., Gunaseelan, K., Nasir, Wnawm., Yoganathan, P., Lee, E. X., Saw, J. E., Yeang, L. J., Koh, P. Y., Lim, S. Y., Teo, S. 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L., Siaw, J. Y., Yam, S. Y., Wilson, L., Aziz, M. R. A., Bondin, J., Zorrilla, C. D., Majbar, A., Sale, D., Abdullahi, L., Osagie, O., Faboya, O., Fatuga, A., Taiwo, A., Nwabuoku, E., Bliksøen, M., Khan, Z. A., Coronel, J., Miranda, C., Vasquez, I., Helguero-Santin, L. M., Rickard, J., Adedeji, A., Alqahtani, S., Rath, M., Niekerk, M. V., Koto, M. Z., Matos-Puig, R., Israelsson, L., Schuetz, T., Yuksek, M. A., Mericliler, M., Uluşahin, M., Yong, G. L., Whitehurst, K., Redgrave, N., Musyoka, C. K., Olivier, J., Lee, K., Cox, M., Farhan-Alanie, M. M. H., Callan, R., Chibuye, C., Ali, T. H. A., Rekhis, S., Rommaneh, M., Sam, Z. H., Pugliesi, T. B., Pardo, G., Blanco, R., Thomas, Hannah S, Weiser, Thomas G, Drake, Thomas M, Knight, Stephen R, Fairfield, Cameron, Ademuyiwa, Adesoji O, Aguilera, Maria Lorena, Alexander, Philip, Al‐Saqqa, Sara W, Borda‐Luque, Giuliano, Costas‐Chavarri, Ainhoa, Ntirenganya, Faustin, Fitzgerald, J Edward, Fergusson, Stuart J, Glasbey, Jame, Ingabire, J.C. Allen, Ismaïl, Lawani, Salem, Hosni Khairy, Kojo, Anyomih Theophilus Teddy, Lapitan, Marie Carmela, Lilford, Richard, Mihaljevic, Andre L, Morton, Dion, Mutabazi, Alphonse Zeta, Nepogodiev, Dmitri, Adisa, Adewale O, Ots, Riinu, Pata, Francesco, Pinkney, Thoma, Poškus, Toma, Qureshi, Ahmad Uzair, Medina, Antonio Ramos‐De, Rayne, Sarah, Shaw, Catherine A, Shu, Sebastian, Spence, Richard, Smart, Neil, Tabiri, Stephen, Bhangu, Aneel, Harrison, Ewen M, Verjee, Azmina, Runigamugabo, Emmy, Altamini, Afnan, Cornick, Jen, Jaffry, Zahra, Khatri, Chetan, Kirby, Andrew, Mohan, Midhun, Recinos, Gustavo, Søreide, Kjetil, Gobin, Neel, Freitas, Ana Vega, Hall, Nigel, Kim, Sung‐Hee, Negida, Ahmed, Khairy, Hosni, Chapman, Stephen J, Arnaud, Alexis P, Manipal, Cutting Edge, Amandito, Radhian, Shawki, Marwan, Hanrahan, Michael, Zilinskas, Justa, Roslani, April Camilla, Goh, Cheng Chun, Irwin, Gareth, Luque, Laura, Shiwani, Hunain, Altamimi, Afnan, Alsaggaf, Mohammed Ubaid, Jeyakumar, Jenifa, Cengiz, Yucel, Raptis, Dmitri A, Glasbey, James C, Modolo, Maria Marta, Iyer, Dushyant, King, Sebastian, Arthur, Tom, Nahar, Sayeda Nazmum, Waterman, Ade, Walsh, Lawani Ismaïl, Agarwal, Arnav, Zani, Augusto, Firdouse, Mohammed, Rouse, Tyler, Liu, Qinyang, Correa, Juan Camilo, Talving, Peep, Worku, Mengistu, Arnaud, Alexi, Kalles, Vassili, Kumar, Basant, Kumar, Sunil, Quek, Roy, Ansaloni, Luca, Altibi, Ahmed, Venskutonis, Donata, Poskus, Toma, Whitaker, John, Msosa, Vanessa, Tew, Yong Yong, Farrugia, Alexia, Borg, Elaine, Bentounsi, Zineb, Gala, Tanzeela, Al‐Slaibi, Ibrahim, Tahboub, Haya, Alser, Osaid H., Romani, Diego, Shu, Sebestian, Major, Piotr, Mironescu, Aurel, Bratu, Matei, Kourdouli, Amar, Ndajiwo, Aliyu, Altwijri, Abdulaziz, Gudal, Ahmad, Jubran, Al Faifi, Seisay, Sam, Lieske, Bettina, Ortega, Irene, Senanayake, Kithsiri J., Abdulbagi, Omar, Raptis, Dmitri, Altinel, Yuksel, Kong, Chia, Teasdale, Ella, Stoddart, Michael, Kabariti, Rakan, Suresh, Sukrit, Gash, Katherine, Narayanan, Ragavan, Maimbo, Mayaba, Fermani, Claudio, Balmaceda, Ruben, Macdermid, Ewan, Chenn, Roxanne, Yong, Cheryl Ou, Edye, Michael, Jarmin, Martin, D'amours, Scott K, Youssef, Daniel, Phillips, Nichola, Brown, Jason, George, Robert, Koh, Cherry, Warren, Oliver, Hanley, Isaac, Dickfos, Marilla, Nawara, Clemen, Öfner, Dietmar, Primavesi, Florian, Mitul, Ashrarur Rahman, Mahmud, Khalid, Hussain, Margub, Hakim, Hafiz, Kumar, Tapan, Oosterkamp, Antje, Assouto, Pamphile A, Lawani, Ismail, Souaibou, Yacoubou Imorou, Tun, Aung Kyaw, Chong, Chean Leung, Devadasar, Giridhar H, Qadir, Muhammad Rashid Minha, Aung, Kyaw Phyo, Yeo, Lee Shi, Castillo, Vanessa Dina Palomino, Munhoz, Monique Moron, Moreira, Gisele, Segundo, Luiz Carlos Barros De Castro, Ferreira, Salim Anderson Khouri, Careta, Maíra Cassa, Kim, Stella Binna, De Sousa, Alexandre Venancio, Cury, Alyne Daltri Lazzarini, Miguel, Gustavo Peixoto Soare, De Freitas, Ana Vega Carreiro, Silvestre, Barbara Pereira, Vianna, Julia Guasti Pinto, Felipe, Carolina Oliveira, Laufer, Luis Alberto Valente, Altoe, Fernanda, Da Silva, Luana Ayre, Pimenta, Marina Luiza, Giuriato, Thiago Fernande, Morais, Paulo Alves Bezerra, Luiz, Jessica Souza, Araujo, Rafael, Menegussi, Juliana, Leal, Marisa, Lima, Caio Vinícius Barroso, Tatagiba, Luiza Sarmento, Leal, Antônio, Santos, Diogo Viniciu, Fraga, Gustavo Pereira, Simoes, Romeo Lage, Stock, Simon, Nigo, Samuel, Kabba, Juana, Ngwa, Tagang Ebogo, Brown, Jame, Azzie, George, Kushwaha, Sameer, Bailey, Karen, Cameron, Brian, Livingston, Michael, Horobjowsky, Alexandre, Deckelbaum, Dan L, Razek, Tarek, Marinkovic, Bori, Grasset, Eugenio, D'aguzan, Nicole, Jimenez, Julio, Macchiavello, Roberto, Zhang, Zhongtao, Guo, Wei, Oh, Junyeong, Zheng, Fei, Montes, Irene, Sierra, Sebastian, Mendez, Manuela, Villegas, Maria Isabel, Arango, Maria Clara Mendoza, Mendoza, Ivan, Aristizã¡bal, Fred Alexander Naranjo, Botero, Jaime Andres Montoya, Riaza, Victor Manuel Quintero, Restrepo, Jakeline, Morales, Carlo, Cruz, Herman, Munera, Alejandro, Karlo, Robert, Domini, Edgar, Mihanovic, Jakov, Radic, Mihael, Zamarin, Kresimir, Pezelj, Nikica, Hache‐Marliere, Manuel, Lemaire, Sylvia Batista, Rivas, Ruben, Khyrallh, Ahmed, Hassan, Ahamed, Shimy, Gamal, Baky Fahmy, Mohamed A, Nabawi, Ayman, Elfil, Mohamed, Ghoneem, Mohamed, Gohar, Muhammad El‐Saied Ahmad Muhammad, Asal, Mohamed, Abdelkader, Mostafa, Gomah, Mahmoud, Rashwan, Hayssam, Karkeet, Mohamed, Gomaa, Ahmed, Hasan, Amr, Elgebaly, Ahmed, Saleh, Omar, Fattah, Ahmad Abdel, Gouda, Abdullah, Elshafay, Abd Elrahman, Gharib, Abdalla, Menshawy, Ahmed, Hanafy, Mohammed, Al‐Mallah, Abdullah, Abdulgawad, Mahmoud, Baheeg, Mohamad, Alhendy, Mohammed, AbdelFattah, Ibrahim, Kenibar, Abdalla, Osman, Omar, Gemeah, Mostafa, Mohammed, Ahmed, Adel, Abdalrahman, Mohammed, Abdelrahman, Sayed, Abdelrahman, Abozaid, Mohamed, Kotb, Ahmed Hafez El‐Badri, Ata, Ali Amin Ahmed, Nasr, Mohammed, Alkammash, Abdelrahman, Saeed, Mohammed, El Hamid, Nader Abd, Attia, Attia Mohamed, El Galeel, Ahmed Abd, Elbanby, Eslam, El‐Dien, Khalid Salah, Hantour, Usama, Alahmady, Omar, Mansour, Billal, Elkorashy, Amr Muhammad, Taha, Emad Mohamed Saeed, Lasheen, Kholod Tarek, Elkolaly, Salma Said, Abdel‐Wahab, Nehal Yosri Elsayed, Abozyed, Mahmoud Ahmed Fathi, Adel, Ahmed, Saeed, Ahmed Moustafa, El Sayed, Gehad Samir, Youssif, Jehad Hassan, Ahmed, Soliman Magdy, El‐Shahat, Nermeen Soubhy, Khedr, Abd El‐Rahman Hegazy, Elsebaaye, Abdelrhman Osama, Elzayat, Mohamed, Abdelraheim, Mohamed, Elzayat, Ibrahim, Warda, Mahmoud, El Deen, Khaled Naser, Elnemr, Abdelrhman Essam, Salah, Omar, Abbas, Mohamed, Rashad, Mona, Elzayyat, Ibrahim, Hemeda, Dalia, Tawfik, Gehad, Salama, Mai, Khaled, Hazem, Seisa, Mohamed, Elshaer, Kareem, Hussein, Abdelfatah, Elkhadrawi, Mahmoud, Afifi, Ahmed Mohamed, Ebrahim, Osama Saadeldeen, Metwally, Mahmoud Mohamed, Elmelegy, Rowida, Elsawahly, Diaa Moustafa Elbendary, Safa, Hisham, Nofal, Eman, Elbermawy, Mohamed, Ghazy, Ahmed Abdelmotaleb, Samih, Hisham, Abdelgelil, Asmaa, Abdelghany, Sarah, El Kholy, Ahmed, Aboraya, Metwally, Elkady, Fatma, Salma, Mahmoud, Samy, Sarah, Fakher, Reem, Aboarab, Aya, Samir, Ahmed, Sakr, Ahmed, Haroun, Abdelrahman, Al‐Aarag, Asmaa Abdel‐Rahman, Elkholy, Ahmed, Elshanwany, Sally, Ghanem, Esraa, Tammam, Ahmed, Hammad, Ali Mohamed, El Shoura, Yousra, El Ashal, Gehad, Antar, Sarah, Mehrez, Sara, Abdelshafy, Mahmoud, Hamad, Maha Gamal Mohamad, Hosh, Mona, Abdallah, Emad, Magdy, Basma, Alzayat, Thuraya, Gamaly, Elsayed, Elfeki, Hossam, Abouzahra, Amany, Elsheikh, Shereen, Elgendy, Fatimah I, El‐Salam, Fathia Abd, Seifelnasr, Osama, Ammar, Mohamed, Eysa, Athar, Sadek, Aliaa, Toeema, Aliaa Gamal, Nasr, Aly, Abuseif, Mohamed, Zidan, Hagar, Barakat, Sara Abd Elmageed, Elsayed, Nadin, Elrasoul, Yasmin Abd, Elkelany, Ahmed, Ammar, Mohamed Sabry, Mustafa, Mennat‐Allah, Hegazy, Yasmin, Etman, Mohamed, Saad, Samar, Alrahawy, Mahmoud, Raslan, Ahmed, Morsi, Mahmoud, Rslan, Ahmed, Sabry, Ahmed, Elwakil, Hager, Shaker, Heba, Abd‐Elrasoul, Yasmin, El‐Kashef, Hussein, Shaalan, Mohamed, Tarek, Areej, Elwan, Ayman, Nayel, Ahmed Ragab, Seif, Mostafa, Emadeldin, Doaa, Ghonaim, Mohamed Ali, Almallah, Ahmad, Fouad, Ahmed, Sayma, Eman Adel, Elbatahgy, Ahmad, El‐Ma'doul, Angham Solaiman, Mosad, Ahmed, Tolba, Hager, Elsorogy, Diaa Eldin Abdelazeem Amin, Mostafa, Hassan Ali, Omar, Amira Atef, El Hameed, Ola Sherief Abd, Lasheen, Ahmed, El Salam, Yasser Abd, Morsi, Ashraf, Ismail, Mohammed, El‐badawy, Hager Ahmed, Amer, Mohamed A, El‐Hamouly, Ahmed Sabry, Attallah, Noura A., Mosalum, Omnia, Afandy, Ahmed, Mokhtar, Ahmed, Abouelnasr, Alaa, Ayad, Sara, Shaker, Ramdan, Sakr, Rokia, Shaker, Ramadan, Amreia, Mahmoud, Elsobky, Soaad, Mustafa, Mohamed, El Magd, Ahmed Abo, Marey, Abeer, Hafez, Amr Tarek, Zalabia, Mohamed F, Mohamed, Mohamed Moamen, Fadel, Amr, Ahmed, Emad Ali, Ali, Ahmad, Alwafai, Mohammad Ghassan, Dwydar, Abdullah, Kharsa, Sara, Mamdouh, Ehab, El‐Sheemy, Hatem, AlYoussef, Ibrahim, Aly, Abouelatta Khairy, Aldalaq, Ahmad, Alnawam, Ehab, Alkhabbaz, Dalia, Saad, Mahmoud, Hussein, Shady, Elazayem, Ahmed Abo, Meshref, Ahmed, Elashmawy, Marwa, Mousa, Mohammed, Nashaat, Ahmad, Ghanem, Sara, Elsayed, Zaynab M, Elwaey, Aya, Elkadsh, Iman, Darweesh, Mariam, Mohameden, Ahmed, Hafez, Mennaallah, Badr, Ahmed, Badwy, Assmaa, El Slam, Mohamed Abd, Elazoul, Mohamed, Al‐Nahrawi, Safwat, Eldamaty, Lotfy, Nada, Fathee, Ameen, Mohamed, Hagar, Aya, Elsehimy, Mohamed, Aboraya, Mohammad, Dawoud, Hossam, El Mesery, Shorouk, El Gendy, Abeer, Abdelkareem, Ahmed, Marey, Ahmed Safwan, Allam, Mostafa, Shehata, Sherif, Abozeid, Khaled, Elshobary, Marwa, Fahiem, Ahmed, Sarsik, Sameh, Hashish, Amel, Zidan, Mohamed, Hashish, Mohamed, Aql, Shaimaa, Elhendawy, Abdelaziz Osman Abdelaziz, Husseini, Mohamed, Kasem, Esraa, Gheith, Ahmed, Elfouly, Yasmin, Soliman, Ahmed Ragab, Ibrahim, Yasmein, Elfouly, Nesma, Fawzy, Ahmed, Hassan, Ahmed, Rashid, Mohammad, Elsherbiny, Abdallah Salah, Sieda, Basem, Badwi, Nermin M, Mohammed, Mohammed Mustafa Hassan, Mohamed, Osama, Habeeb, Mohammad Abdulkhalek, Starr, Nichole, Desta, Semay, Wondimu, Sahlu, Abebe, Nebyou Seyoum, Thomas, Efeson, Asele, Frehun Ayele, Dabessa, Daniel, Abebe, Nebiyou Seyoum, Zerihun, Abebe Bekele, Mentula, Panu, Leppäniemi, Ari, Sallinen, Ville, Scalabre, Aurelien, Frade, Fernanda, Irtan, Sabine, Graffeille, Vivien, Gaignard, Elodie, Alimi, Quentin, Graffieille, Vivien, Abbo, Olivier, Mouttalib, Sofia, Bouali, Ourdia, Hervieux, Erik, Aigrain, Yve, Botto, Nathalie, Faure, Alice, Fievet, Lucile, Panait, Nicoleta, Eyssartier, Emilie, Schmitt, Francoise, Podevin, Guillaume, Parent, Valentine, Martin, Amandine, Arnaud, Alexis Pierre, Muller, Cecile, Bonnard, Arnaud, Peycelon, Matthieu, Abantanga, Franci, Boakye‐Yiadom, Kwaku, Bukari, Mohammed, Owusu, Frank, Awuku‐Asabre, Joseph, Bray, Lemuel Davie, Lytras, Dimitrio, Psarianos, Kyriako, Bamicha, Anastasia, Kefalidi, Eirini, Gemenetzis, Georgio, Dervenis, Christo, Gouvas, Nikolao, Agalianos, Christo, Kontos, Michail, Kouraklis, Gregory, Karousos, Dimitrio, Germanos, Styliano, Marinos, Constantino, Anthoulakis, Christo, Nikoloudis, Nikolao, Mitroudis, Nikolao, Estupinian, Sergio, Forno, Walter, Azmitia, José René Arévalo, Cabrera, Carla Cecilia Ramãrez, Guevara, Romeo, Aguilera, Maria, Mendez, Napoleon, Mendizabal, Cesar Augusto Azmitia, Ramazzini, Pablo, Urquizu, Mario Contrera, Tale, Fernando, Soley, Rafael, Barrios, Emanuel, Barrios, Emmanuel, Rodríguez, Daniel Estuardo Marroquín, Velásquez, Carlos Iván Pérez, Mérida, Sara María Contrera, Regalado, Francisco, Lopez, Mario, Siguantay, Miguel, Lam, Fong Yee, Szeto, Kylie Joan‐yi, Szeto, Charing Cheuk Ling, Li, Wing Sum, Li, Kieran Ka Kei, Leung, Man Fung, Mak, Tony, Ng, Simon, Prasad, SS, Kirishnan, Anand, Gyanchandani, Nidhi, Kumar, Bylapudi Seshu, Rangarajan, Muthukumaran, Bhat, Sriram, Sreedharan, Anjana, Kinnera, S.V., Reddy, Yella, Venugopal, Caranj, Mittal, Abhishek, Nadkarni, Shravan, Lakshmi, Harish Neelamraju, Malik, Puneet, Limaye, Neel, Pai, Sriniva, Jain, Pratik, Khajanchi, Monty, Satoskar, Savni, Satoskar, Rajeev, Mahamood, Abid Bin, Sutanto, Eldaa Prisca Refianti, Soeselo, Daniel Ardian, Tedjaatmadja, Chintya, Rahmawati, Fitriana Nur, Mayasari, Maria, Al‐Hasani, Ruqaya Kadhim Mohammed Jawad, Al‐Hameedi, Hasan Ismael Ibraheem, Ibraheem, Hasan Ismael, Al‐Azraqi, Israa Abdullah Aziz, Sabeeh, Lubna, Kamil, Rahma, Telfah, Muwaffaq Mezeil, Rasendran, Amoudtha, Sheehan, Jacqueline, Kerley, Robert, Normile, Caoimhe, Gilbert, Richard William, Song, Jiheon, Dablouk, Mohamed, Mauro, Linnea, Dablouk, Mohammed Osman, Kielty, Paul, Marks, Eleanor, Gosling, Simon, Mccarthy, Michelle, Mirghani, Diya, Naqvi, Syed Altaf, Wong, Chee Siong, Chung, Siyi, D'cruz, Reuban, Cahill, Ronan, Gosling, Simon George, Fahy, Ciara, Cadogan, Diana Duarte, Powell, Anna, Gilbert, Richard, Clifford, Caroline, Driscoll, Aoife, Paul, Stassen, Lee, Chri, Bowe, Ro, Hutch, William, Mohan, Helen, O'neill, Maeve, Mealy, Kenneth, Danelli, Piergiorgio, Bondurri, Andrea, Maffioli, Anna, Pasini, Mario, Pata, Giacomo, Roncali, Stefano, Silvani, Paolo, Carlucci, Michele, Faccincani, Roberto, Bonavina, Luigi, Macchitella, Yuri, Ceriani, Chiara, Tugnoli, Gregorio, Di Saverio, Salomone, Khattab, Khaled, Paludi, Miguel Angel, Pata, Domenica, Cloro, Luigi Maria, Allegri, Andrea, Coccolini, Federico, Veronese, Ezio, Bortolasi, Luca, Hasheminia, Alireza, Nastri, Giacomo, Canto, Massimiliano Dal, Cucumazzo, Stefano, Benevento, Angelo, Tessera, Gaetano, Grandinetti, Pier Paolo, Maniscalco, Alessio, Lamanna, Giovanni Luca, Turati, Luca, Sgroi, Giovanni, Rausa, Emanuele, Villa, Roberta, Monteleone, Michela, Merlini, David, Grassi, Veronica, Cirocchi, Roberto, Cacurri, Alban, Waleed, Hamza, Diab, Ahmed, Elzowawi, Fathi, Jokubauskas, Manta, Varkalys, Karoli, Pranevicius, Roberta, Ambrozeviciute, Viktorija, Juciute, Simona, Skardžiukaitė, Austė, Bradulskis, Sauliu, Urbanavicius, Lina, Austraite, Aiste, Riauka, Romualda, Dambrauskas, Zilvina, Karumnas, Pauliu, Urniezius, Zigmanta, Zilinskiene, Reda, Rudzenskaite, Anele, Usaityte, Ausrine, Montrimaite, Margarita, Kaselis, Neriju, Strazdas, Andriu, Jokubonis, Kristijona, Maceviciute, Kornelija, Beisa, Virgiliju, Strupas, Kestuti, Laugzemys, Erika, Kolosov, Andrej, Jotautas, Valdemara, Rakita, Igna, Mikalauskas, Sauliu, Kazanavicius, Dariu, Rackauskas, Roka, Rakauskas, Ritaura, Preckailaite, Egle, Coomber, Ro, Johnson, Kenneth, Nowers, Jennifer, Periasammy, Dineshwary, Salleh, Afizah, Das, Andre, Tze, Reuben Goh Ern, Kumar, Milaksh Nirumal, Abdullah, Nik Azim Nik, Kosai, Nik Ritza, Taher, Mustafa, Rajan, Reynu, Chong, Hoong Yin, Agius, Marija, Bezzina, Maureen, Bugeja, Roberta, Vella‐Baldacchino, Martinique, Spina, Andrew, Psaila, Josephine, Francois‐Coridon, Helene, Tolg, Cecilia, Colombani, Jean‐Francoi, Diaz‐Zorrilla, null, De La Medina, Antonio Ramos‐, Gonzalez, Samantha Corro‐Diaz, Jacobe, Mário, Mapasse, Domingo, Snyder, Elizabeth, Oumer, Ramadan, Osman, Mohammed, Mohammad, Aminu, Anyanwu, Lofty‐John, Sheshe, Abdulrahman, Adesina, Alaba, Faturoti, Olubukola, Taiwo, Ogechukwu, Ibrahim, Muhammad Habib, Nasir, Abdulrasheed A, Suleiman, Siyaka Itopa, Adeniyi, Adewale, Adesanya, Opeoluwa, Adebanjo, Ademola, Osuoji, Roland, Atobatele, Kazeem, Ogunyemi, Ayokunle, Williams, Omolara, Oludara, Mobolaji, Oshodi, Olabode, Ademuyiwa, Adesoji, Lawal, AbdulRazzaq Oluwagbemiga, Alakaloko, Felix, Elebute, Olumide, Osinowo, Adedapo, Bode, Christopher, Adesuyi, Abidemi, Tade, Adesoji, Adekoya, Adeleke, Nwokoro, Collin, Ayandipo, Omobolaji O, Lawal, Taiwo Akeem, Ajao, Akinlabi E, Ali, Samuel Sani, Odeyemi, Babatunde, Olori, Samson, Popoola, Ademola, Adeyeye, Ademola, Adeniran, Jame, Lossius, William J., Havemann, Ingemar, Thorsen, Kenneth, Narvestad, Jon Kristian, Soreide, Kjetil, Wold, Trude Beate, Nymo, Linn, Elsiddig, Mohammed, Dar, Manzoor, Bhopal, Kamran Faisal, Iftikhar, Zainab, Furqan, Muhammad Mohsin, Nighat, Bakhtiar, Jawaid, Masood, Khalique, Abdul, Zil‐E‐Ali, Ahsan, Rashid, Anam, Dharamshi, Hasnain Abba, Naqvi, Tahira, Faraz, Ahmad, Anwar, Abdul Wahid, Yaseen, Tahir Muhammad, Shamsi, Ghina Shamim, Shamsi, Ghina, Yaseen, Tahir, Anwer, Wahid, Decoud, Horacio Parede, Aguilera, Omar, Alvarez, Ismael Isaac Zelada, Delgado, Juan Marcelo, Vega, Gustavo Miguel Machain, Lohse, Helmut Alfredo Segovia, Aguilar, Wendy Leslie Messa, Chiong, Jose Antonio Cabala, Bautista, Ana Cecilia Manchego, Huaman, Eduardo, Zegarra, Sergio, Camacho, Rony, Celis, Jose María Vergara, Pozo, Diego Alonso Romani, Hamasaki, José, Temoche, Edilberto, Herrera‐Matta, Jaime, Torres, Carla Pierina García, Barreda, Luis Miguel Alvarez, Ojeda, Ronald Renato Barrionuevo, Garaycochea, Octavio, Mollo, Melanie Castro, Delgado, Mitchelle Solange De Fã Tima Linare, Fujii, Francisco, Durand, Susana Yrma Aranzabal, Basto, Carlos Alejandro Arroyo, Rojas, Nelson Manuel Urbina, Yip, Sebastian Bernardo Shu, Vergara, Ana Lucia Contrera, Moran, Andrea Echevarria Rosa, Luque, Giuliano Borda, Castro, Manuel Rodriguez, Jaramillo, Ramon Alvarado, Sila, George Manrique, Lopez, Crislee Elizabeth, De Leon, Mardelangel Zapata Ponze, Machaca, Massiell, Huaraya, Ronald Coasaca, Arenas, Andy, López, Crislee, Puma, Clara Milagros Herrera, Pino, Wilfredo, Hinojosa, Christian, De Leon, Melanie Zapata Ponze, Limache, Susan, Sila, George Manrrique, Rodriguez, Layza‐Alejandra Mercado, Melo, Renato, Costa‐Maia, Jose, Muralha, Nuno, Sauvat, Frederique, Dan, Ionasc, Hogea, Mircea, Eduard, Pandi, Bratu, Razvan‐Matei, Beuran, Mircea, Diaconescu, Ionut‐Bogdan, Martian, Bogdan‐Valeriu, Iordache, Florin‐Mihail, Vartic, Mihaela, Vida, Lucian Corneliu, Muntean, Liviu Iuliu, Mironescu, Aurel Sandu, Nsengimana, Vizir Jean Paul, Niragire, Alice, Ingabire, Jean De La Croix Allen, Niyirera, Eugene, Zanini, Nicola, Jovine, Elio, Landolfo, Giovanni, Alomar, Ibrahim N., Alnuqaydan, Saleh A., Altwigry, Abdulrahman M., Othman, Moayad, Osman, Nohad, Alqahtani, Ena, Alzahrani, Mohammed, Alyami, Rifan, Aljohani, Emad, Alhabli, Ibrahim, Mikwar, Zaher, Almuallem, Sultan, Nawawi, Abrar, Bakhaidar, Mohamad, Maghrabi, Ashraf A., Alsaggaf, Mohammed, Aljiffry, Murad, Altaf, Abdulmalik, Khoja, Ahmad, Habeebullah, Alaa, Akeel, Nouf, Ghandora, Nashat, Almoflihi, Abdullah, Huwait, Abdulmalik, Al‐shammari, Abeer, Al‐Mousa, Mashael, Alghamdi, Masood, Adham, Walid, Albeladi, Bandar, Alfarsi, Muayad Ahmed, Mahdi, Atif, Al Awwad, Saad, Nouh, Thamer, Hassanain, Mazen, Aldhafeeri, Salman, Sadig, Nawal, Algohary, Osama, Aledrisy, Mohannad, Alrifaie, Ahmad, AlRowais, Mohammed, Althwainy, Amani, Shabkah, Alaa, Alamoudi, Uthman, Alrajraji, Mawaddah, Alghamdi, Basim, Aljohani, Saud, Daqeeq, Abdullah, Al‐Faifi, Jubran J, Jennings, Vicky, Ngayu, Nyawira, Moore, Rachel, Kong, Victor, Kretzmann, Hayden, Connor, Katie, Nel, Daniel, Sampson, Colleen, Panieri, Eugenio, Sishuba, Nosisa, Tun, Myint, Mphatsoe, Albert Mohale, Carreira, Jo‐Anne, Wagener, Mark, Botes, Stefan, Du Plessis, Danelo, Fernandez‐Bueno, Fernando, Aguilar‐Jimenez, Jose, Garcia‐Marin, Jose Andre, García, Lorena Solar, Florez, Luis Joaquín García, Pacheco, Rubén Darío Aria, Pagnozzi, Janet, Quezada, Jimy Harold Jara, Rodicio, Jose Lui, Minguez, German, Rodríguez‐Uría, Raquel, Ugalde, Paul, Lopez‐Arevalo, Camilo, Barneo, Lui, Stuva, Jessica Patricia Gonzale, Ortega‐Vazquez, Irene, Rodriguez, Lorena, Herrera, Norberto, Arachchi, Prasad Pitigala, Senanayake, Wanigasekara Senanayake Mudiyansela, Arachchige, Lalith Asanka Jayasooriya Jayasoori, Sivaganesh, Sivasuriya, Samaraweera, Dulan Irusha, Thanusan, Vimalakanthan, Musa, Ahmed Elgaili Khalid, Balila, Reem Mohammed Hassan, Mohamed, Mohamed Awad Elkarim Hamad, Ali, Hussein, Elabdin, Hagir Zain, Hassan, Alaa, Mahdi, Sefeldin, Ahmed, Hala, Idris, Sahar Abdoun Ishag, Elsayed, Makki, Elsayed, Mohammed, Mahmoud, Mohamed, Boijsen, Magnu, Lundgren, Per‐Olof, Gustafsson, Ulf, Kiasat, Ali, Wogensen, Fredrik, Jurdell, Emma, Thorell, Ander, Thorarinsdottir, Hildur, Utter, Maria, Sundstrom, Sami Martin, Wredberg, Cecilia, Kjellin, Ann, Nyberg, Johanna, Frisk, Bjorn, Sund, Malin, Andersson, Linda, Gunnarsson, Ulf, Cengiz, Yücel, Ahlqvist, Sandra, Royson, Ida Björklund Hanna, Weber, Per, Pahlsson, Hans‐Ivar, Borin, Eva, Hjertberg, Maria, Royson, Hanna, Schmid, Roger, Schivo, Debora, Despotidis, Vasileio, Breitenstein, Stefan, Staerkle, Ralph F, Schadde, Erik, Deichsel, Fabian, Gerosa, Alexandra, Nocito, Antonio, Raptis, Dimitri Aristotle, Mijuskovic, Barbara, Zuber, Marku, Eisner, Luka, Kruspi, Swantje, Reinisch, Katharina Beate, Schoewe, Christin, Novak, Allan, Palma, Adrian F., Teufelberger, Gerfried, Kimaro, Msafiri, King, Rachel, Balkan, Ali Zeynel Abidin, Gumar, Mehmet, Yavuz, Mehmet Ali, Karabacak, Ufuk, Lap, Gokhan, Ozkan, Bahar Busra, Karakahya, Murat, Adams, Ryan, Morton, Robert, Henderson, Liam, Gratton, Ruth, Clement, Keiran David, Chang, Kate Yu‐Ching, Mcnish, David, Mcintosh, Ryan, Milligan, William, Skelly, Brendan, Anderson‐Knight, Hannah, Lawther, Roger, Onimowo, Jemina, Shatkar, Veereanna, Tharmalingam, Shivanee, Woin, Evelina, Fautz, Tessa, Ziff, Oliver, Dindyal, Shiva, Arman, Sam, Talukder, Shagorika, Gadhvi, Vijay, Chew, Luen Shaun, Heath, Jonathan, Blencowe, Natalie, Hallam, Sally, Mannu, Gurdeep Singh, Zachariades, Dimitris‐Christo, Snaith, Ailsa Claire, Hettiarachchi, Thusitha Sampath, Nesaratnam, Arjun, Wheeler, Jame, McCullagh, Darragh, Clements, Joshua Michael, Khan, Ata, Koumpa, Foteini, Neophytou, Christina, Roth, Jessica, Soon, Wai Cheong, Deputy, Mohammed, Ahmed, Ahmed, Ashton, Annelisse, Vincent, Joe, Almy, Jack, Khan, Taufiq, Allen, John Lee Y, Mcintyre, Charlotte Jane, Marshall, Dominic Charle, Sykes, Mark, Behar, Nebil, Jordan, Harriet, Rajjoub, Yaseen, Sherman, Thoma, White, Timothy, Watts, Anna, Ardley, Rohan, Arulampalam, Tan, Shah, Apar, Brown, Damien, Blower, Emma, Sutton, Paul, Gasteratos, Konstantino, Vimalachandran, Dale, Magee, Cathy, Mcguigan, Andrew, Mcaleer, Stephen, Morgan, Clare, Braungart, Sarah, Lafferty, Kirsten, Labib, Peter, Tanase, Andrei, Mangan, Clodagh, Reza, Lillian, Woodward, Helen, Gouldthorpe, Craig, Turner, Megan, Wild, Jonathan R L, Malik, Tom AM, Proctor, Victoria K, Hewage, Kalon, Davies, Jame, Dubois, Andre, Sarwary, Sayed, Zardab, Ali, Grant, Alan, Mcintyre, Robert, Mogan, Yogendra Praveen, Ho, Weiguang, Chong, Bryon Frankie Hon Khi, Tewari, Shirish, Humm, Gemma, Hall, Eriberto Farinella Nigel J, Wright, Naomi J, Major, Christina P, Xerri, Thelma, De Bono, Phoebe, Amin, Jasim, Farhad, Mustafa, Camilleri‐Brennan, John F., Robertson, Andrew G N, Swann, Joanna, Richards, Jame, Jabbar, Aijaz, Attard, Myranda, Burns, Hannah, Macdonald, Euan, Baldacchino, Matthew, Skehan, Jennifer, Camilleri‐Brennan, Julian, Hall, Tom Falconer, Gimzewska, Madelaine, Mclachlan, Greta, Shah, Jamie, Giles, Jame, Chiu, Selina, Weber, Beatrix, Chiu, Selina Man Yeng, Highcock, Saskia, Hassan, Maleeha, Beasley, William, Vlachogiorgos, Apostolo, Dias, Stephen, Maharaj, Geta, Mcdonald, Rosie, Macdonald, Alisdair, Witherspoon, Paul, Baird, Alan, Sarmah, Panchali, Green, Nikki, Youssef, Haney, Cross, Kate, Rees, Clare M, Van Duren, Bernard, Upchurch, Emma, Khan, Khurram, Abudeeb, Haytham, Hammad, Ahmed, Karandikar, Sharad, Bowley, Doug, Karim, Ahmed, Chachulski, Witold, Richardson, Liam, Dawnay, Gile, Thompson, Ben, Mistry, Ajayesh, Ghetia, Millika, Roy, Sudipta, Al‐Obaedi, Ossama, Das, Kaustuv, Prabhudesai, Ash, Cocker, DM, Tan, Jessica Juliana, Tyler, Robert, Di Franco, Filippo, Ayyar, Shruti, Vivekanantham, Sayinthen, Gokani, Shyam, Gillespie, Michael, Gudlaugsdottir, Katrin, Pezas, Theodore, Currow, Chelise, Kim, Matthew Young‐Han, Birring, Amerdip, Edwards, Joanne, Ali, Ased, Das, Suparna, Jha, Madan, Atkinson, Kieran, Luck, Joshua, Fozard, Thoma, Puttick, Michael, Salama, Yahya, Shah, Rohi, Ibrahem, Ahmad Aboelkassem, Ebdewi, Hamdi, Gravante, Gianpiero, El‐Rabaa, Saleem, Nnajiuba, Henry, Allott, Rebecca, Bhargava, Aman, Chan, Zoe, Hassan, Zaffar, Makinde, Misty, Hemingway, David, Dean, Ramzana, Boddy, Alexander, Aber, Ahmed, Patel, Vijay, Parakh, Jehangirshaw, Parthiban, Sunil, Ubhi, Harmony Kaur, Hosein, Simon‐Peter, Ward, Simon, Malik, Kamran, Jennings, Leifa, Newton, Tom, Alkhouri, Mirna, Kang, Min Kyu, Houlden, Christopher, Barry, Jonathan, Raza, Imtanan, Farquharson, Alistair, Bhattacharya, Sanjeet, Chang, Kate, Wilson, Michael S J, Neo, Yan Ning, Ibrahim, Ibrahim, Chan, Emily, Peck, Fraser S, Lim, Pei J, North, Alexander S, Blundell, Rebecca, Williamson, Adam, Fouad, Dina, Minocha, Ashish, Mccarthy, Kathryn, Court, Emma, Chambers, Alice, Yee, Jenna, Tham, Ji Chung, Beaton, Ceri, Walsh, Una, Lockey, Joseph, Bokhari, Salman, Howells, Lara, Griffiths, Megan, Yallop, Laura, Singh, Shailinder, Nasher, Omar, Jackson, Paul, Shariffuddin, Abdul Muiz, Ho, Weng Chee, Wilson, Michael Sj, Pabla, Gurpreet, Ramzi, Saed, Zeidan, Shady, Doughty, Jennifer, Sinha, Sidhartha, Davenport, Ro, Lewis, Jason, Duffy, Leo, Mcaleer, Elizabeth, Williams, Eleanor, Som, Robin, Javed, Omar, Boal, Matthew, Harrison, Nicola, Tafazal, Habib, Brogden, Tom, Obute, Ewen Griffiths Rhalumi Daniel, Glover, Thomas E, Clark, David J, Boshnaq, Mohamed, Akhtar, Mansoor, Capleton, Pascale, Doughan, Samer, Rabie, Mohamed, Mohamed, Ismail, Samuel, Duncan, Dickson, Lauren, Kennedy, Matthew, Dempster, Eleanor, Brown, Emma, Maple, Natalie, Monaghan, Eimear, Wolf, Bernhard, Garland, Alicia, Mcphee, Arthur, Anderson, David, Anderson, Robert, Hassan, Sarah, Smith, Dave, Lund, Jonathan, Boereboom, Catherine, Murphy, Jennifer, Tierney, Gillian, Tou, Samson, Zimmermann, Eleanor Franziska, Smart, Neil Jame, Warwick, Andrea Marie, Stasinou, Theodora, Daniels, Ian, Findlay‐Cooper, Kim, Mitrasinovic, Stefan, Ray, Swayamjyoti, Varcada, Massimo, D'Souza, Rovan, Omara, Sharif, Spurr, Matthew, Parkinson, Lucienne, Hanks, Anthony, Ma, Jennifer, Abington, Emily, Ramcharn, Meera, Williams, Gethin, Winstanley, Joseph, Kennedy, Ewan D., 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Chee Yang, Kulasabanathan, Kavian, Chhabra, Srishti, Kostov, Elisabeth, Harbord, Philippe, Barnacle, Jame, Palliyil, Madan Mohan, Zikry, Mina, Porter, Johnathan, Raslan, Charef, Hafiz, Shazia, Soltani, Niksa, Baillie, Katie, Singh, Priyanka, Sheth, Shailee, Patel, Kishen, Khalili, Mahry, Choi, Jeesoo, Benger, Matthew, Marples, Lucy, Macfarlane, Alastair, Thurairaja, Ramesh, Boyce, Tamsin, Whewell, Harriet, Jones, Elin, Th'ng, Francesca, Robertson, Nichola, Mirza, Ahmad, Saeed, Haroon, Galloway, Simon, Elena, Gia, Afzal, Mohammad, Zakir, Mohamed, Sodde, Peter, Hand, Charle, Sriram, Aiesha, Clark, Tamsyn, Holton, Patrick, Livesey, Amy, Sinha, Yashashwi, Iqbal, Fahad Mujtaba, Bharj, Indervir Singh, Rotundo, Adriana, Jenvey, Cara, Slade, Robert, Golding, David, Haines, Samuel, Ne'ma Abdullah, Ali Adel, Tilston, Thomas W, Loughran, Dafydd, Donoghue, Danielle, Giacci, Lorenzo, Sherif, Mohamed Ashur, Harrison, Peter, Tang, Alethea, Kotecha, Deevia, Elshaer, Mohamed, Urbonas, Toma, Riaz, Amjid, Chapman, Annie, Acharya, Parisha, Shalhoub, Joseph, Grossart, Cathleen, McMorran, David, Mlotshwa, Makhosini, Hawkins, William, Loizides, Sofroni, Krishna, Kandaswamy, Orchard, Melanie, Ho, Chik Wai, Thomson, Peter, Khan, Shahab, Taylor, Fiona, Shukla, Jalak, Howie, Emma Elizabeth, Macdonald, Linda, Komolafe, Olusegun, Mcintyre, Neil, Cragg, Jame, Parker, Jody, Stewart, Duncan, Lintin, Luke, Tracy, Julia, Farooq, Tahir, Molina, George, Kaafarani, Haytham, Beyene, Robel, Sava, Jack, Scott, Mark, Swaroop, Mamta, Kennedy, Raelene, Azodo, Ijeoma A, Heffernan, Daithi, Chun, Tristen, Stephen, Andrew, Sion, Melanie, Weinstein, Michael S., Punja, Viren, Bugaev, Nikolay, Goodstein, Monica, Razmdjou, Shadi, Etchill, Eric, Puyana, Juan Carlo, Kesinger, Matthew, Napolitano, Lena, To, Kathleen, Hemmila, Mark, Todd, Oliver, Jenner, Edward, Hoogakker, Ellen, Grizhja, Besmir, Ymeri, Shpetim, Galiqi, Gezim, Klappenbach, Roberto, Antezana, Diego, Beleño, Alvaro Enrique Mendoza, Costa, Cecilia, Sanchez, Belen, Aviles, Susan, Fermani, Claudio Gabriel, Balmaceda, Rubén, Villalobos, Santiago, Carmona, Juan Manuel, Hamill, Daniel, Deutschmann, Peter, Sandler, Simone, Cox, Daniel, Nataraja, Ram, Sharpin, Claire, Ljuhar, Damir, Gray, Demi, Haines, Morgan, Iyer, Dush, Niranjan, Nithya, D'Amours, Scott, Ashtari, Morvarid, Franco, Helena, Karim, Sabbir, Aman, Nowrin F., Estee, Mahnuma Mahfuz, Salma, Umme, Razzaque, Joyeta, Kanta, Tasnia Hamid, Tori, Sayeeda Aktar, Alamin, Shadid, Roy, Swapnil, Al Amin, Shadid, Karim, Rezaul, Haque, Muhtarima, Faruq, Amreen, Iftekhar, Farhana, O'Shea, Margaret, Padmore, Greg, Jonnalagadda, Ramesh, Litvin, Andrey, Filatau, Aliaksandr, Paulouski, Dzmitry, Shubianok, Maryna, Shachykava, Tatsiana, Khokha, Dziani, Khokha, Vladimir, Djivoh, Fernande, Dossou, Franci, Seto, Djifid Morel, Gbessi, Dansou Gaspard, Noukpozounkou, Bruno, Keke, Kpèmahouton René, Hodonou, Fred, Ahounou, Ernest Yemalin Stephane, Alihonou, Thierry, Dénakpo, Max, Ahlonsou, Germain, Bedada, Alemayehu Ginbo, Nsengiyumva, Carlo, Kwizera, Sandrine, Barendegere, Venerand, Choi, Philip, Jamal, Luai, Chen, Tzu‐Ling, Yip, Chingwan, Zapata, Felipe, Lanau, Maria Isabel Villega, Restrepo, Ivan Mendoza, Giraldo, Ruben Santiago Restrepo, Youssef, Mohamed, Thabet, Waleed, Sanad, Aly, Zaki, Ahmed, Abdel‐Hameed, Noran, Mostafa, Mohamed, Omar, Muhammad Fathi Waleed, Ghanem, Ahmed, Denewar, Adel, Emara, Eman, Rashad, Eman, Sakr, Ahmad, Elashry, Rehab, Emile, Sameh, Khafagy, Toqa, Elhamouly, Sara, Elfarargy, Arwa, Mohamed, Amna Mamdouh, Nagy, Ghada Saied, Esam, Abeer, Elwy, Eman, Hammad, Aya, Khallaf, Salwa, Ibrahim, Eman, Saidbadr, Ahmed, Moustafa, Ahmed, Mohammed, Amany Eldosouky, Elgheriany, Mohammed, Abdelmageed, Eman, Al Raouf, Eman Abd, Elbanby, Esraa Samir, Elmasry, Maha, Farahat, Mahitab Morsy, Mansor, Eman Yahya, Hegazy, Eman Magdy, Gamal, Esraa, Gamal, Heba, Kandil, Hend, Abdelrouf, Doaa Maher, Moaty, Mohamed, Gamal, Dina, El‐Sagheer, Nada, Salah, Mohamed, Magdy, Salma, Salah, Asmaa, Essam, Ahmed, Ali, Ahmed, Badawy, Mahmoud, Ahmed, Sara, Mohamed, Mazed, Assal, Abdelrahman, Sleem, Mohamed, Ebidy, Mai, Elrazek, Aly Abd, Zahran, Diaaaldin, Adam, Nourhan, Nazir, Mohamed, Hassanein, Adel B, Ismail, Ahmed, Elsawy, Amira, Mamdouh, Rana, Mabrouk, Mohamed, Ahmed, Lopna Ahmed Mohamed, Alnaby, Mohamed Hassab, Magdy, Eman, Abd‐Elmawla, Manar, Fahim, Marwan, Mowafy, Bassant, Mahmoud, Moustafa Ibrahim, Allam, Meran, Alkelani, Muhammad, El Gendy, Noran Halim, Aboul‐Naga, Mariam Saad, El‐Din, Reham Alaa, Elgendy, Alyaa Halim, Ismail, Mohamed, Shalaby, Mahmoud, Elsharkawy, Aya Adel, Moghazy, Mahmoud Elsayed, Elbisomy, Khaled Hesham, Shakshouk, Hend Adel Gawad, Hamed, Mohamed Fouad, Ebidy, Mai Mohamed, Ahmed, Hayam, Adel, Israa, Omar, Mohammad Elsayed, Ibrahim, Mohamed, Ghoneim, Omar, Hesham, Omar, Gamal, Shimaa, Hilal, Karim, Arafa, Omar, Awad, Sawsan Adel, Salem, Menatalla, Elsherif, Fawzia Abdellatif, Elsabbagh, Nourhan, Aboelsoud, Moustafa R., Rida, Ahmed Hossam Eldin Fouad, Hossameldin, Amr, Hany, Ethar, Asar, Yomna Hosny, Anwar, Nourhan, Gadelkarim, Mohamed, Abdelhady, Samar, Morshedy, Eman Mohamed, Saad, Reham, Soliman, Nourhan, Salama, Mahmoud, Ezzat, Eslam, Mohamed, Arwa, Ibrahim, Arwa, Fergany, Alaa, Mohammed, Sara, Reda, Aya, Allam, Yomna, Saad, Hanan Adel, Abdelfatah, Afnan, Fathy, Aya Mohamed, El‐Sehily, Ahmed, Kasem, Esraa Abdalmageed, Hassan, Ahmed Tarek Abdelbaset, Mohammed, Ahmed Rabeih, Saad, Abdalla Gamal, Ibrahim, Arij, Hassaan, Amr, Mohammed, Mohammed Mustafa, Elhoseny, Ghada, Magdy, Mohamed, Elkhalek, Esraa Abd, Zakaria, Yehia, Ezzat, Tarek, El Dahab, Ali Abo, Kelany, Mohamed, Arafa, Sara, Hassan, Osama Mokhtar Mohamed, Badwi, Nermin Mohamed, Sleem, Ahmad Saber, Ahmed, Hussien, Abdelbadeai, Kholoud, Abdullah, Mohamed Abozed, Lokman, Muhammad Amsyar Auni, Bahar, Suraya, Abdelazeam, Anan Rady, Adelshone, Abdelrahman, Hasnan, Muhammad Bin, Zulkifli, Athirah, Kamarulzamil, Siti Nur Alia, Elhendawy, Abdelaziz, Latif, Aliang, Adnan, Ahmad Bin, Shaharuddin, Shahadatul, Majid, Aminah Hanum Haji Abdul, Al‐Marakby, Dina, Ismail, Mohamad Jeffrey Bin, Basir, Elissa Rifhan Mohd, Ali, Citra Dewi Mohd, Ata, Aya Yehia, Nasr, Maha, Rezq, Asmaa, Sheta, Ahmed, Tariq, Sherif, Sallam, Abd Elkhalek, Darwish, Abdelrhman KZ, Elmihy, Sohaila, Elhadry, Shady, Farag, Ahmed, Hajeh, Haidar, Abdelaal, Abdelaziz, Aglan, Amro, Zohair, Ahmed, Essam, Mahitab, Moussa, Omar, El‐Gizawy, Esraa, Samy, Mostafa, Ali, Safia, Elhalawany, Esraa, Ata, Ahmed, El Halawany, Mohamed, Nashat, Mohamed, Soliman, Samar, Elazab, Alaa, Samy, Mostada, Abdelaziz, Mohamed A, Ibrahim, Khaled, Ibrahim, Ahmed mohamed, Gado, Ammar, Eldeen, Esraa Alm, loaloa, Mohamed Reda, Abouzaid, Arwa, Eldin, Mostafa Ahmed Bahaa, Hashad, Eman, Sroor, Fathy, Gamil, Doaa, Abdulhakeem, Eman Mahmoud, Zakaria, Mahmoud, Mohamed, Fawzy, Abubakr, Marwan, Ali, Elsayed, Magdy, Hesham, Refaat, Ahmed, Ramadan, Menna Tallah, Mohamed, Mohamed Abdelaty, Mansour, Salma, Amin, Hager Abdul Aziz, Mohamed, Ahmed Rabie, Saami, Mahmoud, Elsayed, Nada Ahmed Reda, Tarek, Adham, Mahmoud, Sabry Mohy Eldeen, El Sayed, Islam Magdy, Reda, Amira, Shawky, Martina Yusuf, Salem, Mohammed Mousa, El‐Din, Shahinaz Alaa, Soliman, Noha Abdullah, Talaat, Muhammed, Alaael‐Dein, Shahinaz, Elhusseiny, Ahmed Abd Elmoen, Abdullah, Noha, Elshaar, Mohammed, Ibraheem, Aya Abdel Fatah, Abdulaziz, Hager, Ismail, Mohammed Kamal, Madkor, Mona Hamdy, Abdelaty, Mohamed, Abdel‐Kader, Sara Mahmoud, Salah, Osama Mohamed, Eldafrawy, Mahmoud, Eldeeb, Ahmed Zaki, Eid, Mostafa Mahmoud, Attia, Attia, Shwky, Ayman, Badenjki, Mohamed Adel, Soliman, Abdelrahman, Al Attar, Samaa Mahmoud, Sayed, Farrag, Sabour, Fahd Abdel, Azizeldine, Mohammed G., Shawqi, Muhammad, Hashim, Abdullah, Aamer, Ahmed, Abdelraouf, Ahmed Mahmoud, Abdelshakour, Mahmoud, Ibrahim, Amal, Mahmoud, Basma, Mahmoud, Mohamed Ali, Qenawy, Mostafa, Rashed, Ahmed M., Dahy, Ahmed, Sayed, Marwa, Shamsedine, Ahmed W., Mohamed, Bakeer, Hasan, Ahmad, Saad, Mahmoud M., Bassit, Khalil Abdul, El‐Latif, Nadia Khalid Abd, Elzahed, Nada, El Kashash, Ahmed, Bekhet, Nada Mohamed, Hafez, Sarah, Gad, Ahmed, Maher, Mahmoud Elkhadragy, Elsameea, Ahmed Abd, Hafez, Mohamed, Sabe, Ahmad, Ahmed, Ataa, Shahine, Ahmed, Dawood, Khaled, Gaafar, Shireen, Husseiny, Reem, Aboelmagd, Omnia, Soliman, Ahmed, Mesbah, Nourhan, Emadeldin, Hossam, Al Meligy, Amgad, Bekhet, Amira Hassan, Hasan, Doaa, Alhady, Khaled, Sabe, Ahmad Khaled, Elnajjar, Mahmoud A., Aboelella, Majed, Hamsho, Ward, Hassan, Ihab, Saad, Hala, Abdelazim, Galaleldin, Mahmoud, Hend, Wael, Noha, Kandil, Ahmedali M, Magdy, Ahmed, Elkholy, Shimaa Said, Adel, Badr Eldin, Dabbour, Kareem, Elsherbiney, Saged, Mattar, Omar, Abdrabou, Abdulshafi Khaled, Aly, Mohammed Yahia Mohamed, Geuoshy, Abdelrahman, Elnagar, Ahmedglal, Ahmed, Saraibrahim, Abdelmotaleb, Ibrahem, Saleh, Amr Ahmed, Saeed, Manar, Mahmoud, Shady, Tawfik, Badreldin Adel, Ismail, Samar Adel, Zakaria, Esraay, Gad, Mariam O., Elhelbawy, Mohamed Salah, Bassem, Monica, Maraie, Noha, Elhadary, Nourhan Medhat, Semeda, Nourhan, Mohamed, Shaza Rabie, Bakry, Hesham Mohammed, Essam, AA, Tarek, Dina, Ashour, Khlood, Elhadad, Alaa, Abdel‐Aty, Abdulrahman, Rakha, Ibrahim, Matter, Sara Mamdouh, Abdelhamed, Rasha, Abdelkader, Omar, Hassaan, Ayat, Soliman, Yasmin, Mohamed, Amna, Farouk, Sara Amr Mohamed, Ibrahim, Eman Mohamed, El‐Taher, Esraa, Mostafa, Merna, Badr, Mohamed Fawzy Mahrou, Elsemelawy, Rofida, El‐Sawy, Aya, Bakr, Ahmad, Al Rafati, Ahmad Abdel Razaq, Saar, Sten, Reinsoo, Arvo, Seyoum, Nebyou, Worku, Tewodro, Fitsum, Agazi, Tolonen, Matti, Parmentier, Benoît, Dardenne, Sabrina, Robert, Elsa, Maillot, Betty, Courboin, Etienne, Hascoet, Juliette, Kaci, Amir Ait, Prudhomme, Thoma, Ballouhey, Quentin, Grosos, Céline, Fourcade, Laurent, Cecilia, Tolg, Jean‐Francois, Colombani, Helene, Francois‐Coridon, Delforge, Xavier, Haraux, Elodie, Dousset, Bertrand, Schiavone, Roberto, Gaujoux, Sebastien, Marret, Jean‐Baptiste, Haffreingue, 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Gandau Naa, Abdul‐Latif, Saiba, Amoako, Philip Taah, Davor, Anthony, Dassah, Victor, Dagoe, Enoch, Kwakyeafriyie, Prince, Akoto, Elliot, Ackom, Eric, Mensah, Ekow, Atkins, Ebenezer Takyi, Coompson, Christian Lari, Ivros, Nikolao, Ferousis, Christoforo, Kalles, Vasileio, Kyriazanos, Ioanni, Barkolias, Christo, Tselos, Angelo, Tzikos, Georgio, Voulgaris, Evangelo, Bamicha, Athanasia, Stefanopoulos, Anastasio, Patoulias, Ioanni, Sfougaris, Dimitrio, Valioulis, Ioanni, Balalis, Dimitrio, Korkolis, Dimitrio, Manatakis, Dimitrios K, Kyrou, Georgio, Karabelias, Georgio, Papaskarlatos, Iason‐Antonio, Konstantina, Kolonia, Zampitis, Nikolao, Papailia, Aspasia, Theodosopoulos, Theodosio, Gkiokas, Georgio, Mitroudi, Magdalini, Panteli, Christina, Feidantsis, Thoma, Farmakis, Konstantino, Kyziridis, Dimitrio, Ioannidis, Oresti, Parpoudi, Styliani, Parasyris, Stavro, Margaritis, Michail, Aguilera‐Arevalo, Maria‐Lorena, Coyoy‐Gaitan, Otto, Rosales, Javier, Tale, Lui, Rodriguez, Servio Tulio Torre, Galvez, Carlos Paz, Cruz, Danilo Herrera, Rosenberg, Guillermo Sanchez, Matheu, Alejandro, Cohen, David Monterroso, Paul, Marie, Charles, Angeline, Lam, Justin Chak Yiu, Yeung, Man Hon Andrew, Fok, Chi Ying Jacquelyn, Li, Ka Hin Gabriel, Lai, Anthony Chuk‐Him, Cheung, Yuk Hong Eric, Wong, Hong Yee, Leung, Ka Wai, Lee, Tien Seng Bryan, Lam, Wai Him, Dao, Weihei, Kwok, Stephanie Hiu‐wai, Chan, Tsz‐Yan Katie, Ng, Yung Kok, Mak, TWC, Foo, Chi Chung, Yang, Jame, Bhatnagar, Ankur, Upadhyaya, Vijaid, Muddebihal, Uday, Dar, Wasim, Janardha, KC, Aruldas, Neerav, Adella, Fidelis Jacklyn, Rulie, Anthonius Santoso, Iskandar, Ferdy, Setiawan, Jonny, Evajelista, Cicilia Viany, Natalie, Hani, Suyadi, Arlindawati, Gunawan, Rudy, Karismaningtyas, Herlin, Mata, Lusi Padma Sulistianingsih, Andika, Ferry Fitriya Ayu, Hasanah, Afifatun, Widiastini, T Ariani, Purwaningsih, Nurlaila Ayu, Mukin, Annisa Dewi Fitriana, Rahmah, Dina Faizatur, Nurqistan, Hazmi Dwinanda, Arsyad, Hasbi Maulana, Adhitama, Novia, 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Dione, Almanon, Christel Leanne, Walędziak, Maciej, Roszkowski, Rafał, Janik, Michał, Lasek, Anna, Radkowiak, Dorota, Rubinkiewicz, Mateusz, Fernandes, Cristina, Muntean, Liviu, Popa, Mariuca, Mircea, Hogea, Diaconescu, Bogdan, Bratu, Matei Razvan, Negoi, Ionut, Ciubotaru, Cezar, Ingabire, J.C Allen, Uzabumwana, Norbert, Duhoranenayo, Dieudonne, Idris, Faisal, Alghamdi, Mohammed Saleh A., Maghrabi, Ashraf, Alkaaki, Aroub, Turkustani, Sondo, Khalifah, Eyad, Albiety, Adel, Sahel, Sarah, Alshareef, Reham, Najjar, Mohammed, Alzahrani, Ahmed, Alghamdi, Ahmed, Alhazmi, Wedyan, Al Saied, Ghiath, Alamoudi, Mohammed, Riaz, Muhammed Masood, Alhassan, Basmah, Altamimi, Abdullah, Alyahya, Reem, Al Subaie, Norah, Al Bastawis, Fatema, Khan, Roaa, Radojkovic, Milan, Jeremic, Ljiljana, Nestorovic, Milica, Law, Jia Hao, Tan, Keith Say Kwang, Tan, Ryan Choon Kiat, Tan, Joel Kin, Joel, Lau Wen Liang, Chan, Xue Wei, Leong, Faith Qi Hui, Chong, Choon Seng, Koh, Sharon, Lee, Kai Yin, Lee, Kuok Chung, Pluke, Kent, Dedekind, Britta, Nashidengo, Puyearashid, Hampton, Mark Ian, Joosten, Johanna, Sobnach, Sanju, Roodt, Liana, Sander, Anthony, Pape, Jame, Maistry, Niveshni, Ndwambi, Phumudzo, Kinandu, Kamau, Du Toit, Frederick, Ellison, Quinn, Burger, Sule, Grobler, DC, Khulu, Lawrence Bongani, Leusink, Astrid, Kariem, Nazmie, Gouws, Juan, Chu, Kathryn, Bougard, Heather, Noor, Fazlin, Dell, Angela, Van Straten, Stephanie, Khamajeet, Arvin, Tshisola, Serge Kapenda, Kabongo, Kalangu, Moodley, Yoshan, Anderson, Frank, Madiba, Thandinkosi, Plooy, Flip, Hartford, Leila, Chilton, Gareth, Karjiker, Parveen, Mabitsela, Matlou Ernest, Ndlovu, Sibongile Ruth, Badicel, Maria, Jaich, Robert, Ruiz‐Tovar, Jaime, Garcia‐Florez, Lui, Otero‐Díez, Jorge L., Pérez, Virginia Ramo, Suárez, Nuria Aguado, García, Javier Minguez, Moreno, Sara Corral, Collado, Maria Vicenta, Carneros, Virginia Jiménez, Septiem, Javier García, Gonzalez, Mariana, Picardo, Antonio, Esteban, Enrique, Ferrero, Esther, Espin‐Basany, Eloy, Blanco‐Colino, Ruth, Andriola, Valeria, Contreras, Elisa, Bernardo, Carmen García, Sanz, Sandra, León, Alberto Miyar, Dorismé, Asnel, Rodicio, Joselui, Suarez, Aida, Stuva, Jessica, Vico, Tamara Diaz, Fernandez‐Vega, Laura, Soldevila‐Verdeguer, Carla, Sena‐Ruiz, Fatima, Pujol‐Cano, Natalia, Diaz‐Jover, Paula, Garcia‐Perez, José Maria, Segura‐Sampedro, Juan Jose, Pineño‐Flores, Cristina, Ambrona‐Zafra, David, Craus‐Miguel, Andrea, Jimenez‐Morillas, Patricia, Mazzella, Angela, Jayathilake, A.B, Thalgaspitiya, S.P.B, Wijayarathna, L.S., Wimalge, P.M.S.N., Sanni, Hakeem Ayomi, Okenabirhie, Ogheneochuko, Homeida, Anmar, Younis, Abobaker, Omer, Omer Abdelbagi, Abdulaziz, Mustafa, Mussad, Ali, Adam, Ali, Björklund, Ida, Sokratous, Aresti, Breistrand, Michaela, Sigurdadottir, Johanna, Nikberg, Maziar, Chabok, Abba, Elbe, Peter, Saraste, Deborah, Rutkowski, Wiktor, Forlin, Louise, Niska, Karoliina, Oswald, Denni, Peros, Georgio, Bluelle, Rafael, Reinisch, Katharina, Frey, Daniel, Palma, Adrian, Zumbühl, Luciu, Werder, Gabriela, Mahanty, Silke, Widmer, Lukas Werner, Müller, Julia, Gübeli, Alissa, Zuk, Grzegorz, Gulcicek, Osman Bilgin, Vartanoglu, Talar, Kose, Emin, Karahan, Servet Rustu, Aydin, Mehmet Can, Sahbaz, Nuri Alper, Halicioglu, Ilkay, Alis, Halil, Sapci, Ipek, Adıyaman, Can, Pektaş, Ahmet Murat, Cengiz, Turgut Bora, Tansoker, Ilkan, Işler, Vedatcan, Cevik, Muazzez, Mutlu, Deniz, Ozben, Volkan, Ozmen, Berk Bari, Bayram, Sefa, Yolcu, Sinem, Kobal, Berna Buse, Toto, Ömer Faruk, Çakaloğlu, Haluk Cem, Karabulut, Kagan, Mutlu, Vahit, Celik, Saban, Semiz, Anil, Bodur, Selim, Gül, Enisburak, Murutoglu, Busra, Yildirim, Reyyan, Baki, Bahadir Emre, Arslan, Ekin, Guner, Ali, Tomas, Kadir, Walker, Nathan, Shrimanker, Nikhita, Cole, Simon, Breslin, Ryan, Srinivasan, Ravi, Hunter, Kristina, Al‐Bahrani, Ahmed, Mairs, Nora Grace, Rocke, Alistair, Dick, Lachlan, Qureshi, Mobeen, Chowdhury, Debkumar, Wright, Naomi, Skerritt, Clare, Kufeji, Dorothy, Ho, Adrienne, Dissanayake, Tharindra, Tennakoon, Athula, Ali, Wadah, Tan, Charlene, O'Neill, Stephen, Knight, Stephen, Nassif, Dima, Sharma, Abhishek, White, Rebecca, Mehdi, Aia, Post, Nathan, Kalakouti, Eliana, Dashnyam, Enkhbat, Stourton, Frederick, Mykoniatis, Ioanni, Wong, Francisca, Gupta, Ashish, Shatkar, Veeranna, Kadiwar, Suraj, Smedley, Alexander, Wakefield, Rebecca, Herrod, Philip, Blackwell, Jame, Cohen, Fraser, Bandi, Ashwath, Bond‐Smith, Gile, Farhangmehr, Neda, Perenyei, Miklo, Ireland, Philip, Bowling, Kirk, Bunting, David, Longstaff, Lydia, Keogh, Kenneth, Jeon, Hyunjin, Iqbal, Muhammad Rafaih, Khosla, Shivun, Jeffery, Anna, Perera, Jame, Alhammali, Tariq, Oram, Shaun, Kidd, Thoma, Cullen, Fraser, Owen, Christopher, Wilson, Michael, Chiu, Seehui, Sarafilovic, Hannah, Ploski, Jennifer, Evans, Elizabeth, Abbas, Athar, Kamya, Sylvia, Ishak, Norzawani, Bisset, Carly, Andress, Cedar, Chin, Ye Ru, Patel, Priya, Evans, David, Haslegrave, Aidan, Boggon, Adam, Laurie, Kirsten, Mann, Thoma, Mansuri, Anahita, Davies, Rachel, Griffiths, Ewen, Shahbaz, Aized Raza, Eng, Calvin, Din, Farhat, L'Heveder, Ariadne, Park, Esther H.G., Ravishankar, Ramanish, McIntosh, Kirsten, Yau, Jih Dar, Chan, Luke, McGarvie, Susan, Tang, Lingshan, Lim, Hui, Yap, Suhhuey, Park, Jay, Ng, Zhan Herr, Mirza, Shahrukh, Ang, Yun Lin, Walls, Luke, Roy, Chloe, Paterson‐Brown, Simon, Mclean, Kenneth, D'Souza, Michelle S, Pronin, Savva, Henshall, David Ewart, Ter, Eunice Zuling, English, William, Morgan, Catrin, Townsend, Dominic, Maciejec, Laura, Mahdi, Shareef, Akpenyi, Onyinye, Hall, Elisabeth, Caydiid, Hanaan, Rob, Zakaria, Abbott, Tom, Torrance, Hew D, Johnston, Robin, Gani, Mohammed Akil, Rajmohan, Shivanchan, Majid, Kiran, Smith, Christopher, Palliyil, Madanmohan, Patel, Sanjay, Nicholson, Luke, Harvey, Neil, Shillito, Sam, Kershaw, Suzanne, Bamford, Rebecca, Orton, Peter, Reunis, Elke, Jama, Guled M., Dhillon, Dharminder, Patel, Khyati, Nanthakumaran, Shayanthan, Heard, Rachel, Chen, Kar Yan, Barmayehvar, Behrad, Datta, Uttaran, Kamarajah, Sivesh K, Tani, Sobhana Iftekhar, Donnelly, Philippa, Walker, Michael, Blacker, Sarah, Kaul, Anil, Paramasivan, Arjun, Farag, Sameh, Nessa, Ashrafun, Awadallah, Salwa, Lim, Jieqi, Ng, James Chean Khun, Kiran, Ravi P., Murray, Alice, Dasari, Mohini, Puyana, Juan, Haddad, Nadeem, Zielinski, Martin, Choudhry, Asad, Caliman, Celeste, Beamon, Mieshia, Duane, Therese, Myers, Jonathan, Deal, Rebecca, Makupe, Alex, Musowoya, Joseph, Van Der Naald, Niel, Kumwenda, Dayson, Reece‐Smith, Alex, Otten, Kar, Verbeek, Anna, Prins, Marloe, Suarez, Alibeth Andres Baquero, Deane, Chelsea, Dijan, Emilio, Elfiky, Mahmoud, Koskenvuo, Laura, Thollot, Aurore, Limoges, Bernard, Capito, Carmen, Alexandre, Challine, Kotobi, Henri, Leroux, Julien, Pinnagoda, Kalitha, Henric, Nicola, Azzis, Olivier, Rosello, Olivier, Francois, Poddevin, Etienne, Sara, Buisson, Philippe, Hmila, Sophian, Clegg‐Lamptey, Joe‐Nat, Imoro, Osman, Abem, Owusu Emmanuel, Papageorgiou, Dimitrio, Soulou, Vasiliki, Asturias, Sabrina, Peña, Lenin, O'Connor, Donal B, Luc, Alberto Reali, Russo, Alfio Alessandro, Ruzzenente, Andrea, Taddei, Antonio, Cona, Camilla, Bottini, Corrado, Pascale, Giovanni, Rotunno, Giuseppe, Solaini, Leonardo, Pascale, Marco Maria, Notarnicola, Margherita, Corbellino, Mario, Sacco, Michele, Ubiali, Paolo, Cautiero, Roberto, Bocchetti, Tommaso, Muzio, Elena, Guglielmo, Vania, Morandi, Eugenio, Mao, Patrizio, De Luca, Emilia, Ali, Farah Mahmoud, Žilinskas, Justa, Kondrotas, Pauliu, Baltrunas, Roberta, Kutkevicius, Juoza, Ignatavicius, Povila, Tan, Choy Ling, Siaw, Jia Yng, Yam, Sir Young, Wilson, Ling, Aziz, Mohamed Rezal Abdul, Bondin, John, Zorrilla, Carmina Diaz, Majbar, Ana, Sale, Danjuma, Abdullahi, Lawal, Osagie, Olabisi, Faboya, Omolara, Fatuga, Adedeji, Taiwo, Agboola, Nwabuoku, Emeka, Bliksøen, Marte, Khan, Zain Ali, Coronel, Jazmin, Miranda, Cesar, Vasquez, Idelso, Helguero‐Santin, Luis M., Rickard, Jennifer, Adedeji, Adesina, Alqahtani, Saleh, Rath, Max, Niekerk, Michael Van, Koto, Modise Zacharia, Matos‐Puig, Roel, Israelsson, Leif, Schuetz, Tobia, Yuksek, Mahmut Arif, Mericliler, Meric, Uluşahin, Mehmet, Yong, Guo Liang, Whitehurst, Katharine, Redgrave, Natalie, Musyoka, Caroluce K, Olivier, Jame, Lee, Kathryn, Cox, Michael, Farhan‐Alanie, Muhamed M H, Callan, Rory, Chibuye, Chali, Ali, Tebian Hassanein Ahmed, Rekhis, Syrine, Rommaneh, Muna, Sam, Zi Hao, Pugliesi, Thays Brunelli, Pardo, Gabriel, Blanco, Ruth, and Acibadem University Dspace
Subjects: Adult, Male, barriers, humanos, checklist, surgery, human development index, GlobalSurg Collaborative, WHO Surgical Safety Checklist , mortality, emergency, laparotomy, World Health Organization, seguridad del paciente, NO, Cohort Studies, lista de control, estudios prospectivos, Humans, tasa de supervivencia, Prospective Studies, implementation, estudios de cohortes, Surgery, health, Emergency Treatment, 11 Medical and Health Sciences, mediana edad, Digestive System Surgical Procedures, Aged, anciano, Laparotomy, Science & Technology, Original Articles, adulto, Middle Aged, checklist, WHO, procedimientos quirúrgicos del sistema digestivo, Checklist, Survival Rate, Elective Surgical Procedures, laparotomía, tratamiento de urgencia, Original Article, Female, Patient Safety, Life Sciences & Biomedicine
Abstract: Background The World Health Organization (WHO) Surgical Safety Checklist has fostered safe practice for 10 years, yet its place in emergency surgery has not been assessed on a global scale. The aim of this study was to evaluate reported checklist use in emergency settings and examine the relationship with perioperative mortality in patients who had emergency laparotomy. Methods In two multinational cohort studies, adults undergoing emergency laparotomy were compared with those having elective gastrointestinal surgery. Relationships between reported checklist use and mortality were determined using multivariable logistic regression and bootstrapped simulation. Results Of 12 296 patients included from 76 countries, 4843 underwent emergency laparotomy. After adjusting for patient and disease factors, checklist use before emergency laparotomy was more common in countries with a high Human Development Index (HDI) (2455 of 2741, 89.6 per cent) compared with that in countries with a middle (753 of 1242, 60.6 per cent; odds ratio (OR) 0.17, 95 per cent c.i. 0.14 to 0.21, P < 0001) or low (363 of 860, 422 per cent; OR 008, 007 to 010, P < 0.001) HDI. Checklist use was less common in elective surgery than for emergency laparotomy in high-HDI countries (risk difference -94 (95 per cent c.i. -11.9 to -6.9) per cent; P < 0001), but the relationship was reversed in low-HDI countries (+121 (+7.0 to +173) per cent; P < 0001). In multivariable models, checklist use was associated with a lower 30-day perioperative mortality (OR 0.60, 0.50 to 073; P < 0.001). The greatest absolute benefit was seen for emergency surgery in low- and middle-HDI countries. Conclusion Checklist use in emergency laparotomy was associated with a significantly lower perioperative mortality rate. Checklist use in low-HDI countries was half that in high-HDI countries., This work was funded by DFID/MRC/Wellcome Trust Joint Global Health Trial Development Grant (MR/N022114/1). A National Institute for Health Research (NIHR) Global Health Research Unit Grant (NIHR 17-0799) is supporting the establishment of surgical research units in a subset of contributing low-income countries. The views expressed are those of the authors and not necessarily those of the National Health Service, NIHR or UK Department of Health and Social Care. The study funder had no role in study design, data collection, data analysis, data interpretation or writing of the report. The corresponding author had full access to all the data in the study and had final responsibility for the decision to submit for publication.
Published: 2019

11. Evaluation of functional status among patients undergoing maintenance treatments for opioid use disorders

Author: Juan Jesús Ruíz Ruíz, José María Martínez Delgado, Nuria García, Bartolomé Baena, The ANDOPIO Study Group, [Ruíz Ruíz,JJ] Centro Provincial de Drogodependencias, Málaga, Spain. [Martinez Delgado,JM] Centro Provincial de Drogodependencias, Cádiz, Spain. [García-Marchena,N] Unidad de Adicciones Servicio de Medicina Interna, Institut D’Investigació en Ciènces de La Salut Germans Trias I Pujol (IGTP), Campus Can Ruti, Badalona, Barcelona, Spain. [García-Marchena,N] Instituto de Investigación Biomédica de Málaga (IBIMA), Málaga, Spain., and This work has been funded by Sociedad Médica Andaluza de Adicciones y Patologías Médicas Asociadas (SOMAPA) and supported by Research Project funded by Consejería de Salud y Bienestar Social, Junta de Andalucía Fundación Progreso y Salud (PI-0140-2018). NGM holds a Sara Borrell research contract (CD19/00019) funded by Instituto de Salud Carlos III (ISC-III) and European Regional Development Funds-European Union (ERDF-EU).
Subjects: Trastornos relacionados con opiáceos, Estado funcional, medicine.medical_specialty, Medicine (miscellaneous), Sexual dysfunction, Anthropology, Education, Sociology and Social Phenomena::Social Sciences::Sociology::Social Problems::Social Behavior Disorders [Medical Subject Headings], Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], 03 medical and health sciences, 0302 clinical medicine, Seroepidemiologic Studies, Metadona, Health care, Chemicals and Drugs::Organic Chemicals::Ketones::Methadone [Medical Subject Headings], medicine, Opioid use disorders, Opiate Substitution Treatment, Humans, 030212 general & internal medicine, Chemicals and Drugs::Heterocyclic Compounds::Alkaloids::Opiate Alkaloids::Morphinans::Buprenorphine [Medical Subject Headings], Psychiatry, Diseases::Chemically-Induced Disorders::Substance-Related Disorders::Opioid-Related Disorders [Medical Subject Headings], Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Drug Therapy::Opiate Substitution Treatment [Medical Subject Headings], Buprenorfina, business.industry, Research, Opioid use, Disfunciones sexuales fisiológicas, Public Health, Environmental and Occupational Health, Functional status, Opioid-Related Disorders, Buprenorphine, Diseases::Male Urogenital Diseases::Genital Diseases, Male::Sexual Dysfunction, Physiological [Medical Subject Headings], Psychiatry and Mental health, Health psychology, Functional Status, Opioid, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Seroepidemiologic Studies [Medical Subject Headings], medicine.symptom, Public aspects of medicine, RA1-1270, business, 030217 neurology & neurosurgery, Methadone, medicine.drug
Abstract: Background Methadone and buprenorphine are the most prevalent types of opioid maintenance programs in Andalusia. The main objective is comparing the functional status of patients with pharmacological opioid maintenance treatments according to different socio-demographic characteristic, health and disabilities domains and sexual difficulties. Methods A total of 593 patients from the Andalusia community, 329 were undergoing methadone treatment and 264 were undergoing buprenorphine treatment. The patients were interviewed by socio-demographic and opioid-related variables, assessed by functioning, disability and health domains (WHODAS 2.0.) and for sexual problems (PRSexDQ-SALSEX). Results We found significant differences in the socio-demographic and the opioid-related variables as the onset of opioid use, being on previous maintenance programs, opioid intravenous use, the length of previous maintenance programs, polydrug use and elevated seroprevalence rates (HCV and HIV) between the methadone group and the buprenorphine group. Regarding health and disability domains there were differences in the Understanding and communication domain, Getting around domain, Participation in society domain and in the WHODAS 2.0. simple and complex score, favoring buprenorphine-treated patients. The methadone group referred elevated sexual impairments compared with the buprenorphine group. Opioid-related variables as seroprevalence rates, other previous lifetime maintenance program, the daily opioid dosage and the daily alcohol use are the most discriminative variables between both groups. Participation in society variables and sexual problems were the most important clinical variables in distinguishing the methadone group from the buprenorphine group regarding their functional status. Conclusions The methadone group showed higher prevalence in opioid dependence-related variables, elevated disabilities in participation in society activities and sexual problems compared with the buprenorphine group. This study shows the importance of carry out a functional evaluation in the healthcare follow-up, especially in those areas related with social activity and with sexual problems.
Published: 2021

12. Is magnification necessary to confirm visual inspection of cervical abnormalities? A randomized trial in Peru.

Author: Winkler JL, Lewis K, Del Aguila R, Gonzales M, Delgado JM, Tsu WD, and Sellors JW
Abstract: OBJECTIVES: Cervical cancer is the leading cause of cancer death among women in developing countries. This study was designed to evaluate whether visual inspection with acetic acid and magnification (VIAM) improved confirmation of cervical lesions as compared to confirmation with visual inspection with acetic acid (VIA) without magnification when used by physicians. METHODS: From April-December 2004, women in San Martin, Peru, who were referred as VIA-positive by an 'obstetriz' (a professional midwife with 6 years of university training) were randomized into two groups for confirmatory screening by a physician using either VIA or VIAM with an AviScope,(trade mark) a hand-held 4x magnification scope with a green light source. The reference standard for the presence or absence of cervical neoplasia was colposcopy and directed biopsy, as required. RESULTS: A total of 358 women participated in the study; 161 had a confirmatory examination with VIAM and 159 with VIA. Sensitivity for low- or high-grade lesions was 68% with VIA and 77% with VIAM, and specificity was 62% with VIA and 63% with VIAM; however, these differences were not statistically significant. CONCLUSIONS: For settings where physician confirmation of cervical abnormalities identified through visual inspection is required and available, this study demonstrates that VIAM had no significant advantage over VIA. [ABSTRACT FROM AUTHOR]
Published: 2008
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13. Mitochondria as sensors of intracellular pathogens.

Author: Delgado JM and Pernas L
Abstract: Mitochondria must sense their environment to enable cells and organisms to adapt to diverse environments and survive during stress. However, during microbial infection, an evolutionary pressure since the inception of the eukaryotic cell, these organelles are traditionally viewed as targets for microbes. In this opinion we consider the perspective that mitochondria are domesticated microbes that sense and guard their 'host' cell against pathogens. We explore potential mechanisms by which mitochondria detect intracellular pathogens and induce mitochondria-autonomous responses that activate cellular defenses., Competing Interests: Declaration of interests The authors declare no competing interests., (Copyright © 2024. Published by Elsevier Ltd.)
Published: 2024
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14. An unexpected journey for BNIP3.

Author: Delgado JM and Shoemaker CJ
Subjects: Animals, Humans, Autophagy physiology, Lysosomes metabolism, Mitochondria metabolism, Mitochondrial Proteins metabolism, Proteasome Endopeptidase Complex metabolism, Membrane Proteins metabolism, Mitophagy physiology, Proto-Oncogene Proteins metabolism
Abstract: Mitophagy is a cellular process that enables the selective degradation of damaged, dysfunctional, or superfluous mitochondria. During mitophagy, specific proteins recognize and tag mitochondria for degradation. These tagged mitochondria are engulfed by specialized structures called phagophores that then mature into autophagosomes/mitophagosomes. Mitophagosomes subsequently transport their mitochondrial cargo to lysosomes, where the mitochondria are broken down and recycled. While the PINK1-PRKN-dependent mitophagy pathway is well understood, mitophagy can also occur independently of this pathway. BNIP3 and BNIP3L/NIX, paralogous membrane proteins on the outer mitochondrial membrane (OMM), serve as ubiquitin-independent mitophagy receptors. Historically, BNIP3 regulation was thought to be primarily transcriptional through HIF1A (hypoxia inducible factor 1 subunit alpha). However, recent work has revealed a significant post-translational dimension, highlighting the strong role of the ubiquitin-proteasome system (UPS) in BNIP3 regulation. With these emerging concepts in mind, we aimed to develop a unified understanding of how steady-state levels of BNIP3 are established and maintained and how this regulation governs underlying cell physiology.
Published: 2024
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15. Comparison of the Backbone Dynamics of Dehaloperoxidase-Hemoglobin Isoenzymes.

Author: González-Delgado JM, Thompson PM, Andrałojć W, Gdaniec Z, Ghiladi RA, and Franzen S
Subjects: Animals, Isoenzymes metabolism, Hydrogen Peroxide metabolism, Hemoglobins chemistry, Peroxidases chemistry, Peroxidase chemistry, Crystallography, X-Ray, Histidine chemistry, Polychaeta chemistry, Polychaeta metabolism
Abstract: Dehaloperoxidase (DHP) is a multifunctional hemeprotein with a functional switch generally regulated by the chemical class of the substrate. Its two isoforms, DHP-A and DHP-B, differ by only five amino acids and have an almost identical protein fold. However, the catalytic efficiency of DHP-B for oxidation by a peroxidase mechanism ranges from 2- to 6-fold greater than that of DHP-A depending on the conditions. X-ray crystallography has shown that many substrates and ligands have nearly identical binding in the two isoenzymes, suggesting that the difference in catalytic efficiency could be due to differences in the conformational dynamics. We compared the backbone dynamics of the DHP isoenzymes at pH 7 through heteronuclear relaxation dynamics at 11.75, 16.45, and 19.97 T in combination with four 300 ns MD simulations. While the overall dynamics of the isoenzymes are similar, there are specific local differences in functional regions of each protein. In DHP-A, Phe35 undergoes a slow chemical exchange between two conformational states likely coupled to a swinging motion of Tyr34. Moreover, Asn37 undergoes fast chemical exchange in DHP-A. Given that Phe35 and Asn37 are adjacent to Tyr34 and Tyr38, it is possible that their dynamics modulate the formation and migration of the active tyrosyl radicals in DHP-A at pH 7. Another significant difference is that both distal and proximal histidines have a 15-18% smaller S 2 value in DHP-B, thus their greater flexibility could account for the higher catalytic activity. The distal histidine grants substrate access to the distal pocket. The greater flexibility of the proximal histidine could also accelerate H 2 O 2 activation at the heme Fe by increased coupling of an amino acid charge relay to stabilize the ferryl Fe(IV) oxidation state in a Poulos-Kraut "push-pull"-type peroxidase mechanism.
Published: 2024
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16. Polarizable AMOEBA Model for Simulating Mg 2+ ·Protein·Nucleotide Complexes.

Author: Delgado JM, Nagy PR, and Varma S
Subjects: Cations, Divalent, Proteins chemistry, Molecular Dynamics Simulation, Adenosine Triphosphate, Thermodynamics, Amoeba
Abstract: Molecular mechanics (MM) simulations have the potential to provide detailed insights into the mechanisms of enzymes that utilize nucleotides as cofactors. In most cases, the activities of these enzymes also require the binding of divalent cations to catalytic sites. However, modeling divalent cations in MM simulations has been challenging. The inclusion of explicit polarization was considered promising, but despite improvements over nonpolarizable force fields and despite the inclusion of "Nonbonded-fix (NB-fix)" corrections, errors in interaction energies of divalent cations with proteins remain large. Importantly, the application of these models fails to reproduce the experimental structural data on Mg 2+ ·Protein·ATP complexes. Focusing on these complexes, here we provide a systematic assessment of the polarizable AMOEBA model and recommend critical changes that substantially improve its predictive performance. Our key results are as follows. We first show that our recent revision of the AMOEBA protein model (AMOEBABIO18-HFC), which contains high field corrections (HFCs) to induced dipoles, dramatically improves Mg 2+ -protein interaction energies, reducing the mean absolute error (MAE) from 17 to 10 kcal/mol. This further supports the general applicability of AMOEBABIO18-HFC. The inclusion of many-body NB-fix corrections further reduces MAE to 6 kcal/mol, which amounts to less than 2% error. The errors are estimated with respect to vdW-inclusive density functional theory that we benchmark against CCSD(T) calculations and experiments. We also present a new model of ATP with revised polarization parameters to better capture its high field response, as well as new vdW and dihedral parameters. The ATP model accurately predicts experimental Mg 2+ -ATP binding free energy in the aqueous phase and provides new insights into how Mg 2+ associates with ATP. Finally, we show that molecular dynamics (MD) simulations of Mg 2+ ·Kinase·ATP complexes carried out with these improvements lead to a better agreement in global and local catalytic site structures between MD and X-ray crystallography.
Published: 2024
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17. The ER membrane protein complex restricts mitophagy by controlling BNIP3 turnover.

Author: Delgado JM, Shepard LW, Lamson SW, Liu SL, and Shoemaker CJ
Subjects: Membrane Proteins metabolism, Mitochondrial Membranes metabolism, Autophagy physiology, Mitochondrial Proteins genetics, Mitochondrial Proteins metabolism, Mitophagy physiology, Mitochondria genetics, Mitochondria metabolism
Abstract: Lysosomal degradation of autophagy receptors is a common proxy for selective autophagy. However, we find that two established mitophagy receptors, BNIP3 and BNIP3L/NIX, are constitutively delivered to lysosomes in an autophagy-independent manner. This alternative lysosomal delivery of BNIP3 accounts for nearly all its lysosome-mediated degradation, even upon mitophagy induction. To identify how BNIP3, a tail-anchored protein in the outer mitochondrial membrane, is delivered to lysosomes, we performed a genome-wide CRISPR screen for factors influencing BNIP3 flux. This screen revealed both known modifiers of BNIP3 stability as well as a pronounced reliance on endolysosomal components, including the ER membrane protein complex (EMC). Importantly, the endolysosomal system and the ubiquitin-proteosome system regulated BNIP3 independently. Perturbation of either mechanism is sufficient to modulate BNIP3-associated mitophagy and affect underlying cellular physiology. More broadly, these findings extend recent models for tail-anchored protein quality control and install endosomal trafficking and lysosomal degradation in the canon of pathways that tightly regulate endogenous tail-anchored protein localization., (© 2023. The Author(s).)
Published: 2024
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18. Hydrogen bonding patterns and C-H...π interactions in the structure of the antiparkinsonian drug (R)-rasagiline mesylate determined using laboratory and synchrotron X-ray powder diffraction data.

Author: Dugarte-Dugarte AJ, Toro RA, van de Streek J, Henao JA, Fitch AN, Dejoie C, Delgado JM, and Díaz de Delgado G
Abstract: The structure of (R)-rasagiline mesylate [(R)-RasH + ·Mes - ], an active pharmaceutical ingredient used to treat Parkinson's disease, is presented. The structure was determined from laboratory and synchrotron powder diffraction data, refined using the Rietveld method, and validated and optimized using dispersion-corrected DFT calculations. The unit-cell parameters obtained in both experiments are in good agreement and the refinement with both datasets converged to good agreement factors. The final parameters obtained from laboratory data were a = 5.4905 (8), b = 6.536 (2), c = 38.953 (3) Å, V = 1398.0 (4) Å 3 and from synchrotron powder data were a = 5.487530 (10) Å, b = 6.528939 (12) Å, c = 38.94313 (9) Å, V = 1395.245 (5) Å 3 with Z = 4 and space group P2 1 2 1 2 1 . Preferred orientation was properly accounted for using the synchrotron radiation data, leading to a March-Dollase parameter of 1.140 (1) instead of the 0.642 (1) value obtained from laboratory data. In the structure, (R)-RasH + moieties form layers parallel to the ab plane connected by mesylate ions through N-H...O and C-H...O hydrogen bonds. These layers stack along the c axis and are further connected by C-H...π interactions. Hirshfeld surface analysis and fingerprint plot calculations indicate that the main interactions are: H...H (50.9%), H...C/C...H (27.1%) and H...O/O...H (21.1%)., (open access.)
Published: 2023
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19. Phosphoprotein phosphatase activity positively regulates oligomeric pyrin to trigger inflammasome assembly in phagocytes.

Author: Malik HS, Magnotti F, Loeven NA, Delgado JM, Kettenbach AN, Henry T, and Bliska JB
Subjects: Humans, Animals, Mice, Pyrin genetics, Pyrin metabolism, Macrophages metabolism, Phosphoprotein Phosphatases genetics, Mutation, Inflammasomes metabolism, Protein Processing, Post-Translational
Abstract: Importance: Pyrin, a unique cytosolic receptor, initiates inflammatory responses against RhoA-inactivating bacterial toxins and effectors like Yersinia's YopE and YopT. Understanding pyrin regulation is crucial due to its association with dysregulated inflammatory responses, including Familial Mediterranean Fever (FMF), linked to pyrin gene mutations. FMF mutations historically acted as a defense mechanism against plague. Negative regulation of pyrin through PKN phosphorylation is well established, with Yersinia using the YopM effector to promote pyrin phosphorylation and counteract its activity. This study highlights the importance of phosphoprotein phosphatase activity in positively regulating pyrin inflammasome assembly in phagocytic cells of humans and mice. Oligomeric murine pyrin has S205 phosphorylated before inflammasome assembly, and this study implicates the dephosphorylation of murine pyrin S205 by two catalytic subunits of PP2A in macrophages. These findings offer insights for investigating the regulation of oligomeric pyrin and the balance of kinase and phosphatase activity in pyrin-associated infectious and autoinflammatory diseases., Competing Interests: The authors declare no conflict of interest.
Published: 2023
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20. Creatine and creatinine quantified using nuclear magnetic resonance: A method validation study and clinical associations between circulating creatine and fatigue in kidney transplant recipients.

Author: Post A, Garcia E, Shalaurova I, Matyus SP, González-Delgado JM, Doorenbos CSE, van der Veen Y, Shah SH, Kraus WE, Kremer D, Knobbe TJ, Bakker SJL, Dullaart RPF, and Connelly MA
Subjects: Male, Humans, Adult, Middle Aged, Aged, Female, Creatinine, Fatigue, Magnetic Resonance Spectroscopy, Creatine, Kidney Transplantation
Abstract: Background: A potential contributor to fatigue in kidney transplant recipients (KTR) may be impaired creatine homeostasis. We developed and validated a high-throughput NMR assay allowing for simultaneous measurement of circulating creatine and creatinine, and determined plasma creatine and estimated intramuscular creatine concentrations in KTRs, delineated their determinants and explored their associations with self-reported fatigue., Methods: An NMR assay was developed and validated for measurement of circulating creatinine and creatine concentrations. Plasma creatine and creatinine concentrations were measured in 618 KTR. Fatigue was assessed using the checklist individual strength. Associations of creatine parameters with fatigue was assessed using linear mixed effect models., Results: The NMR-based assay had good sensitivity, precision and demonstrated linearity across a large range of values. Among KTR, the mean age was 56 ± 13 years, 62% were men and eGFR was 54 ± 18 ml/min/1.73 m 2 . Plasma creatine concentration was 27 [19-39] µmol/L. Estimated intramuscular creatine concentration was 27 ± 7 mmol/kg. Higher plasma creatine concentration and higher estimated intramuscular creatine concentration were independently associated with a lower total fatigue score and less motivation problems., Conclusion: An NMR method for measurement of circulating creatine and creatinine which offers the potential for accurate and efficient quantification was developed. The found associations suggest that improving creatine status may play a beneficial role in mitigating fatigue., Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2023 The Author(s). Published by Elsevier B.V. All rights reserved.)
Published: 2023
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21. Hospital-based proton therapy implementation during the COVID pandemic: early clinical and research experience in a European academic institution.

Author: Calvo FA, Palma J, Serrano J, Cambeiro M, Meiriño R, Martin S, Azcona D, Pedrero D, Aguilar B, Delgado JM, Moran V, Viñals A, Cabello P, Panizo E, Lassaletta A, Gibert C, Sancho L, de Miguel JMF, de Sierra BA, Alcázar A, Suarez V, Alonso A, Gallardo G, and Aristu J
Subjects: Humans, Child, Pandemics prevention & control, Hospitals, Proton Therapy, COVID-19 epidemiology, Head and Neck Neoplasms
Abstract: Introduction: A rapid deploy of unexpected early impact of the COVID pandemic in Spain was described in 2020. Oncology practice was revised to facilitate decision-making regarding multimodal therapy for prevalent cancer types amenable to multidisciplinary treatment in which the radiotherapy component searched more efficient options in the setting of the COVID-19 pandemic, minimizing the risks to patients whilst aiming to guarantee cancer outcomes., Methods: A novel Proton Beam Therapy (PBT), Unit activity was analyzed in the period of March 2020 to March 2021. Institutional urgent, strict and mandatory clinical care standards for early diagnosis and treatment of COVID-19 infection were stablished in the hospital following national health-authorities' recommendations. The temporary trends of patients care and research projects proposals were registered., Results: 3 out of 14 members of the professional staff involved in the PBR intra-hospital process had a positive test for COVID infection. Also, 4 out of 100 patients had positive tests before initiating PBT, and 7 out of 100 developed positive tests along the weekly mandatory special checkup performed during PBT to all patients. An update of clinical performance at the PBT Unit at CUN Madrid in the initial 500 patients treated with PBT in the period from March 2020 to November 2022 registers a distribution of 131 (26%) pediatric patients, 63 (12%) head and neck cancer and central nervous system neoplasms and 123 (24%) re-irradiation indications. In November 2022, the activity reached a plateau in terms of patients under treatment and the impact of COVID pandemic became sporadic and controlled by minor medical actions. At present, the clinical data are consistent with an academic practice prospectively (NCT05151952). Research projects and scientific production was adapted to the pandemic evolution and its influence upon professional time availability. Seven research projects based in public funding were activated in this period and preliminary data on molecular imaging guided proton therapy in brain tumors and post-irradiation patterns of blood biomarkers are reported., Conclusions: Hospital-based PBT in European academic institutions was impacted by COVID-19 pandemic, although clinical and research activities were developed and sustained. In the post-pandemic era, the benefits of online learning will shape the future of proton therapy education., (© 2023. The Author(s).)
Published: 2023
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22. The ER membrane protein complex governs lysosomal turnover of a mitochondrial tail-anchored protein, BNIP3, to restrict mitophagy.

Author: Delgado JM, Wallace Shepard L, Lamson SW, Liu SL, and Shoemaker CJ
Abstract: Lysosomal degradation of autophagy receptors is a common proxy for selective autophagy. However, we find that two established mitophagy receptors, BNIP3 and BNIP3L/NIX, violate this assumption. Rather, BNIP3 and NIX are constitutively delivered to lysosomes in an autophagy-independent manner. This alternative lysosomal delivery of BNIP3 accounts for nearly all of its lysosome-mediated degradation, even upon mitophagy induction. To identify how BNIP3, a tail-anchored protein in the outer mitochondrial membrane, is delivered to lysosomes, we performed a genome-wide CRISPR screen for factors influencing BNIP3 flux. By this approach, we revealed both known modifiers of BNIP3 stability as well as a pronounced reliance on endolysosomal components, including the ER membrane protein complex (EMC). Importantly, the endolysosomal system regulates BNIP3 alongside, but independent of, the ubiquitin-proteosome system (UPS). Perturbation of either mechanism is sufficient to modulate BNIP3-associated mitophagy and affect underlying cellular physiology. In short, while BNIP3 can be cleared by parallel and partially compensatory quality control pathways, non-autophagic lysosomal degradation of BNIP3 is a strong post-translational modifier of BNIP3 function. More broadly, these data reveal an unanticipated connection between mitophagy and TA protein quality control, wherein the endolysosomal system provides a critical axis for regulating cellular metabolism. Moreover, these findings extend recent models for tail-anchored protein quality control and install endosomal trafficking and lysosomal degradation in the canon of pathways that ensure tight regulation of endogenous TA protein localization.
Published: 2023
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23. Corrigendum: Practice-oriented solutions integrating intraoperative electron irradiation and personalized proton therapy for recurrent or unresectable cancers: Proof of concept and potential for dual FLASH effect.

Author: Calvo FA, Ayestaran A, Serrano J, Cambeiro M, Palma J, Meiriño R, Morcillo MA, Lapuente F, Chiva L, Aguilar B, Azcona D, Pedrero D, Pascau J, Delgado JM, Aristu J, Alonso A, and Prezado Y
Abstract: [This corrects the article DOI: 10.3389/fonc.2022.1037262.]., (Copyright © 2023 Calvo, Ayestaran, Serrano, Cambeiro, Palma, Meiriño, Morcillo, Lapuente, Chiva, Aguilar, Azcona, Pedrero, Pascau, Delgado, Aristu, Alonso and Prezado.)
Published: 2023
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24. Progress in Plasmonic Sensors as Monitoring Tools for Aquaculture Quality Control.

Author: Quintanilla-Villanueva GE, Maldonado J, Luna-Moreno D, Rodríguez-Delgado JM, Villarreal-Chiu JF, and Rodríguez-Delgado MM
Subjects: Animals, Surface Plasmon Resonance methods, Aquaculture, Quality Control, Fiber Optic Technology, Biosensing Techniques methods
Abstract: Aquaculture is an expanding economic sector that nourishes the world's growing population due to its nutritional significance over the years as a source of high-quality proteins. However, it has faced severe challenges due to significant cases of environmental pollution, pathogen outbreaks, and the lack of traceability that guarantees the quality assurance of its products. Such context has prompted many researchers to work on the development of novel, affordable, and reliable technologies, many based on nanophotonic sensing methodologies. These emerging technologies, such as surface plasmon resonance (SPR), localised SPR (LSPR), and fibre-optic SPR (FO-SPR) systems, overcome many of the drawbacks of conventional analytical tools in terms of portability, reagent and solvent use, and the simplicity of sample pre-treatments, which would benefit a more sustainable and profitable aquaculture. To highlight the current progress made in these technologies that would allow them to be transferred for implementation in the field, along with the lag with respect to the most cutting-edge plasmonic sensing, this review provides a variety of information on recent advances in these emerging methodologies that can be used to comprehensively monitor the various operations involving the different commercial stages of farmed aquaculture. For example, to detect environmental hazards, track fish health through biochemical indicators, and monitor disease and biosecurity of fish meat products. Furthermore, it highlights the critical issues associated with these technologies, how to integrate them into farming facilities, and the challenges and prospects of developing plasmonic-based sensors for aquaculture.
Published: 2023
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25. Practice-oriented solutions integrating intraoperative electron irradiation and personalized proton therapy for recurrent or unresectable cancers: Proof of concept and potential for dual FLASH effect.

Author: Calvo FA, Ayestaran A, Serrano J, Cambeiro M, Palma J, Meiriño R, Morcillo MA, Lapuente F, Chiva L, Aguilar B, Azcona D, Pedrero D, Pascau J, Delgado JM, Aristu J, and Prezado Y
Abstract: Background: Oligo-recurrent disease has a consolidated evidence of long-term surviving patients due to the use of intense local cancer therapy. The latter combines real-time surgical exploration/resection with high-energy electron beam single dose of irradiation. This results in a very precise radiation dose deposit, which is an essential element of contemporary multidisciplinary individualized oncology., Methods: Patient candidates to proton therapy were evaluated in Multidisciplinary Tumor Board to consider improved treatment options based on the institutional resources and expertise. Proton therapy was delivered by a synchrotron-based pencil beam scanning technology with energy levels from 70.2 to 228.7 MeV, whereas intraoperative electrons were generated in a miniaturized linear accelerator with dose rates ranging from 22 to 36 Gy/min (at Dmax) and energies from 6 to 12 MeV., Results: In a period of 24 months, 327 patients were treated with proton therapy: 218 were adults, 97 had recurrent cancer, and 54 required re-irradiation. The specific radiation modalities selected in five cases included an integral strategy to optimize the local disease management by the combination of surgery, intraoperative electron boost, and external pencil beam proton therapy as components of the radiotherapy management. Recurrent cancer was present in four cases (cervix, sarcoma, melanoma, and rectum), and one patient had a primary unresectable locally advanced pancreatic adenocarcinoma. In re-irradiated patients (cervix and rectum), a tentative radical total dose was achieved by integrating beams of electrons (ranging from 10- to 20-Gy single dose) and protons (30 to 54-Gy Relative Biological Effectiveness (RBE), in 10-25 fractions)., Conclusions: Individual case solution strategies combining intraoperative electron radiation therapy and proton therapy for patients with oligo-recurrent or unresectable localized cancer are feasible. The potential of this combination can be clinically explored with electron and proton FLASH beams., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2022 Calvo, Ayestaran, Serrano, Cambeiro, Palma, Meiriño, Morcillo, Lapuente, Chiva, Aguilar, Azcona, Pedrero, Pascau, Delgado, Aristu and Prezado.)
Published: 2022
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26. Intra-Operative Electron Radiation Therapy: An Update of the Evidence Collected in 40 Years to Search for Models for Electron-FLASH Studies.

Author: Calvo FA, Serrano J, Cambeiro M, Aristu J, Asencio JM, Rubio I, Delgado JM, Ferrer C, Desco M, and Pascau J
Abstract: Introduction: The clinical practice and outcome results of intraoperative electron radiation therapy (IOeRT) in cancer patients have been extensively reported over 4 decades. Electron beams can be delivered in the promising FLASH dose rate., Methods and Materials: Several cancer models were approached by two alternative radiobiological strategies to optimize local cancer control: boost versus exclusive IOeRT. Clinical outcomes are revisited via a bibliometric search performed for the elaboration of ESTRO/ACROP IORT guidelines., Results: In the period 1982 to 2020, a total of 19,148 patients were registered in 116 publications concerning soft tissue sarcomas (9% of patients), unresected and borderline-resected pancreatic cancer (22%), locally recurrent and locally advanced rectal cancer (22%), and breast cancer (45%). Clinical outcomes following IOeRT doses in the range of 10 to 25 Gy (with or without external beam fractionated radiation therapy) show a wide range of local control from 40 to 100% depending upon cancer site, histology, stage, and treatment intensity. Constraints for normal tissue tolerance are important to maintain tumor control combined with acceptable levels of side effects., Conclusions: IOeRT represents an evidence-based approach for several tumor types. A specific risk analysis for local recurrences supports the identification of cancer models that are candidates for FLASH studies.
Published: 2022
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27. A single dose of dietary nitrate supplementation protects against endothelial ischemia-reperfusion injury in early postmenopausal women.

Author: Somani YB, Soares RN, Gosalia J, Delgado JM, Flanagan M, Basu S, Kim-Shapiro DB, Murias JM, and Proctor DN
Subjects: Cross-Over Studies, Dietary Supplements, Double-Blind Method, Endothelium, Vascular physiology, Female, Humans, Nitric Oxide pharmacology, Postmenopause, Nitrates, Reperfusion Injury prevention & control
Abstract: The onset of menopause and accompanying changes to ovarian hormones often precedes endothelial dysfunction in women. In particular, accelerated impairments in macrovascular and microvascular function coincide with the loss of estrogen, as does impaired endothelial responses to ischemia-reperfusion (IR) injury. In healthy, early postmenopausal women ( n = 12; 3.9 ± 1.5 years since menopause) we tested the hypothesis that acute dietary nitrate (NO 3 - ) supplementation would improve endothelial function and attenuate the magnitude of endothelial dysfunction following whole-arm IR in comparison with placebo. In this randomized, double-blind, placebo-controlled, crossover study we tested participants before and after NO 3 - -rich (BR nitrate ) and NO 3 - -depleted (BR placebo ) beetroot juice (BR) consumption, as well as following IR injury, and 15 min after IR to assess recovery. Analyses with repeated-measures general linear models revealed a condition × time interaction for brachial artery flow-mediated dilation (FMD; P = 0.04), and no interaction effect was found for the near-infrared spectroscopy-derived reperfusion slope ( P = 0.86). Follow-up analysis showed a significant decline in FMD following IR injury with BR placebo in comparison with all other timepoints (all, P < 0.05), while this decline was not present with BR nitrate (all, P > 0.05). Our findings demonstrate that a single dose of dietary NO 3 - minimizes IR-induced macrovascular endothelial dysfunction in healthy, early postmenopausal women, but does not improve resting macrovascular and microvascular function. Trial registration number: NCT03644472. Novelty: In healthy, early postmenopausal women, a single dose of NO 3 - -rich BR can protect against IR-induced endothelial dysfunction. This protection may be due to nitric oxide bioactivity during IR rather than improved endothelial function prior to the IR protocol per se.
Published: 2022
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28. CuO-NPs Improve Biosynthesis of Bioactive Compounds in Lettuce.

Author: Gaucin-Delgado JM, Ortiz-Campos A, Hernandez-Montiel LG, Fortis-Hernandez M, Reyes-Pérez JJ, Gonzáles-Fuentes JA, and Preciado-Rangel P
Abstract: The application of metallic nanoparticles improves the yield and content of bioactive compounds in plants. The aim of the present study was to determine the effects of the foliar application of copper nanoparticles (CuO-NPs) in the yield and content of bioactive compounds in lettuce. Different concentrations of CuO-NPs (0, 0.5, 1, 2, 4, and 6 mg mL -1 ) were applied in lettuce. The yield, nutraceutical quality, and enzymatic activity were determined. Foliar spraying of CuO-NPs induced an increase in the biosynthesis of bioactive compounds. In addition to an increase in the activity of the enzymes superoxide dismutase (SOD) and catalase (CAT) in lettuce plants, there were no negative effects on yield. Therefore, with the application of CuO-NPs, better quality lettuces are produced for the human diet due to the higher production of bioactive compounds.
Published: 2022
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29. Crystal structure from X-ray powder diffraction data, DFT-D calculation, Hirshfeld surface analysis, and energy frameworks of ( RS )-trichlorme-thia-zide.

Author: Toro RA, Dugarte-Dugarte A, van de Streek J, Henao JA, Delgado JM, and Díaz de Delgado G
Abstract: The structure of racemic ( RS )-trichlorme-thia-zide [systematic name: ( RS )-6-chloro-3-(di-chloro-meth-yl)-1,1-dioxo-3,4-di-hydro-2 H -1λ 6 ,2,4-benzo-thia-di-azine-7-sulfonamide], C 8 H 8 Cl 3 N 3 O 4 S 2 ( RS -TCMZ), a diuretic drug used in the treatment of oedema and hypertension, was determined from laboratory X-ray powder diffraction data using DASH [David et al. (2006 ▸). J. Appl. Cryst. 39 , 910-915.], refined by the Rietveld method with TOPAS-Academic [Coelho (2018 ▸). J. Appl. Cryst. 51 , 210-218], and optimized using DFT-D calculations. The extended structure consists of head-to-tail dimers connected by π-π inter-actions which, in turn, are connected by C-Cl⋯π inter-actions. They form chains propagating along [101], further connected by N-H⋯O hydrogen bonds to produce layers parallel to the ac plane that stack along the b -axis direction, connected by additional N-H⋯O hydrogen bonds. The Hirshfeld surface analysis indicates a major contribution of H⋯O and H⋯Cl inter-actions (32.2 and 21.7%, respectively). Energy framework calculations confirm the major contribution of electrostatic inter-actions ( E elec ) to the total energy ( E tot ). A comparison with the structure of S -TCMZ is also presented., (© Toro et al. 2022.)
Published: 2022
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30. Excel Methods to Design and Validate in Microelectronics (Complementary Metal-Oxide-Semiconductor, CMOS) for Biomedical Instrumentation Application.

Author: Dieck-Assad G, Rodríguez-Delgado JM, and González Peña OI
Subjects: Computer Simulation, Equipment Design, Humans, Oxides, Amplifiers, Electronic, Semiconductors
Abstract: CMOS microelectronics design has evolved tremendously during the last two decades. The evolution of CMOS devices to short channel designs where the feature size is below 1000 nm brings a great deal of uncertainty in the way the microelectronics design cycle is completed. After the conceptual idea, developing a thinking model to understand the operation of the device requires a good "ballpark" evaluation of transistor sizes, decision making, and assumptions to fulfill the specifications. This design process has iterations to meet specifications that exceed in number of the available degrees of freedom to maneuver the design. Once the thinking model is developed, the simulation validation follows to test if the design has a good possibility of delivering a successful prototype. If the simulation provides a good match between specifications and results, then the layout is developed. This paper shows a useful open science strategy, using the Excel software, to develop CMOS microelectronics hand calculations to verify a design, before performing the computer simulation and layout of CMOS analog integrated circuits. The full methodology is described to develop designs of passive components, as well as CMOS amplifiers. The methods are used in teaching CMOS microelectronics to students of electronic engineering with industrial partner participation. This paper describes an exhaustive example of a low-voltage operational transconductance amplifier (OTA) design which is used to design an instrumentation amplifier. Finally, a test is performed using this instrumentation amplifier to implement a front-end signal conditioning device for CMOS-MEMS biomedical applications.
Published: 2021
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31. Intensive competency-based training strategy in a National Hospital in times of Pandemic.

Author: Camputaro LA, Bello Quezada ME, Hoyos Arango WA, Bortoli RG, Ruiz Zelaya FA, Diaz Moreno MM, Delgado Delgado JM, Márquez Magaña MS, Vigne Cuellar PA, and Sanchez MI
Subjects: Adult, El Salvador epidemiology, Female, Health Workforce, Hospitals, Public standards, Humans, Inservice Training standards, Male, Pandemics, SARS-CoV-2, COVID-19 epidemiology, COVID-19 therapy, Clinical Competence standards, Hospitals, Public organization & administration, Inservice Training organization & administration
Published: 2021
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32. Molecular basis for higher affinity of SARS-CoV-2 spike RBD for human ACE2 receptor.

Author: Delgado JM, Duro N, Rogers DM, Tkatchenko A, Pandit SA, and Varma S
Subjects: Allosteric Regulation, Humans, Mutation, Protein Binding, Receptors, Virus chemistry, Receptors, Virus metabolism, Thermodynamics, Angiotensin-Converting Enzyme 2 chemistry, Angiotensin-Converting Enzyme 2 metabolism, Molecular Dynamics Simulation, SARS-CoV-2 chemistry, SARS-CoV-2 metabolism, Spike Glycoprotein, Coronavirus chemistry, Spike Glycoprotein, Coronavirus metabolism
Abstract: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has caused substantially more infections, deaths, and economic disruptions than the 2002-2003 SARS-CoV. The key to understanding SARS-CoV-2's higher infectivity lies partly in its host receptor recognition mechanism. Experiments show that the human angiotensin converting enzyme 2 (ACE2) protein, which serves as the primary receptor for both CoVs, binds to the receptor binding domain (RBD) of CoV-2's spike protein stronger than SARS-CoV's spike RBD. The molecular basis for this difference in binding affinity, however, remains unexplained from X-ray structures. To go beyond insights gained from X-ray structures and investigate the role of thermal fluctuations in structure, we employ all-atom molecular dynamics simulations. Microseconds-long simulations reveal that while CoV and CoV-2 spike-ACE2 interfaces have similar conformational binding modes, CoV-2 spike interacts with ACE2 via a larger combinatorics of polar contacts, and on average, makes 45% more polar contacts. Correlation analysis and thermodynamic calculations indicate that these differences in the density and dynamics of polar contacts arise from differences in spatial arrangements of interfacial residues, and dynamical coupling between interfacial and non-interfacial residues. These results recommend that ongoing efforts to design spike-ACE2 peptide blockers will benefit from incorporating dynamical information as well as allosteric coupling effects., (© 2021 Wiley Periodicals LLC.)
Published: 2021
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33. Development and Usability Validation of a Social Robot Platform for Physical and Cognitive Stimulation in Elder Care Facilities.

Author: Cobo Hurtado L, Viñas PF, Zalama E, Gómez-García-Bermejo J, Delgado JM, and Vielba García B
Abstract: This article shows our work for developing an elder care platform for social interaction and physical and cognitive stimulation using the Pepper robot and Android OS as clients, based on the knowledge acquired on our long-term social robotics research experience. The first results of the user's acceptance of the solution are presented in this article. The platform is able to provide different services to the user, such as information, news, games, exercises or music. The games, which have a bi-modal way of interacting (speech and a touch screen interface), have been designed for cognitive stimulation based on the items of the mini-mental state examination. The results of the user's performance are stored in a cloud database and can be reviewed by therapists through a web interface that also allows them to establish customized therapy plans for each user. The platform has been tested and validated, first using adult people and then deployed to an elder care facility where the robot has been interacting with users for a long period of time. The results and feedback received have shown that the robot can help to keep the users physically and mentally active as well as establish an emotional link between the user and the robot.
Published: 2021
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34. Evaluation of Emergency First Response's Competency in Undergraduate College Students: Enhancing Sustainable Medical Education in the Community for Work Occupational Safety.

Author: Dieck-Assad G, González Peña OI, and Rodríguez-Delgado JM
Subjects: Curriculum, Emergencies, Humans, SARS-CoV-2, Students, COVID-19, Education, Medical, Occupational Health, Students, Medical
Abstract: Worldwide, people's quality of health has been decreasing due to bad eating habits that have generated an increase in diseases such as diabetes, hypertension, overweight, as well as an increase in hours of the daily workday and stress. This situation can generate sudden illness and work accidents where the need to have knowledge in emergency first response (EFR) is necessary for all. Unfortunately, workshops and courses to certify EFR individuals are usually taught only to healthcare professionals. Therefore, to address this need a EFR project has been developed at the Tecnológico de Monterrey (TEC) which consists of a multidisciplinary challenge to train, certify, and evaluate students' competency as "emergency first responders" in medical emergencies and healthcare awareness. This EFR project has been performed for one week, every year since 2015, and constitutes a joint venture among academic departments, faculty, and industrial/government institutions, which work together in multidisciplinary projects, providing a source of innovative proposals. The EFR project at TEC has provided instruction and certification for 966 students between 2015 to 2019 and this study has analyzed results considering a sample size of 197 participants. The combination of exam evaluation, medical emergency skills verification, and project proposal results indicate that most students reach skill levels between 2 and 3 in EFR competency after successfully completing the program, regardless of their year of study or the undergraduate program they are enrolled on. This evaluation emphasizes the compromise of the institution and its students in preparation for new living under sanitary conditions for pandemic conditions such as COVID-19.
Published: 2021
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35. The Potential Use of a Thin Film Gold Electrode Modified with Laccases for the Electrochemical Detection of Pyrethroid Metabolite 3-Phenoxybenzaldehyde.

Author: Esquivel-Blanco VA, Quintanilla-Villanueva GE, Villarreal-Chiu JF, Rodríguez-Delgado JM, and Rodríguez-Delgado MM
Abstract: There is increasing interest in developing portable technologies to detect human health threats through hybrid materials that integrate specific bioreceptors. This work proposes an electrochemical approach for detecting 3-Phenoxybenzaldehyde (3-PBD), a biomarker for monitoring human exposure to pyrethroid pesticides. The biosensor uses laccase enzymes as an alternative recognition element by direct oxidation of 3-PBD catalysts by the enzyme onto thin-film gold electrodes. The thin-film gold electrode modified by the immobilized laccase was characterized by Fourier-transform infrared spectrometry and scanning electron microscopy. The detection method's electrochemical parameters were established, obtaining a linear range of 5 t 50 μM, the limit of detection, and quantification of 0.061 and 2.02 μM, respectively. The proposed biosensor's analytical performance meets the concentration of pyrethroids detected in natural environments, reflecting its potential as an alternative analytical tool for monitoring the pyrethroid insecticide's presence.
Published: 2021
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36. Evaluation of functional status among patients undergoing maintenance treatments for opioid use disorders.

Author: Ruíz Ruíz JJ, Martinez Delgado JM, and García-Marchena N
Subjects: Functional Status, Humans, Methadone therapeutic use, Opiate Substitution Treatment, Seroepidemiologic Studies, Buprenorphine therapeutic use, Opioid-Related Disorders drug therapy, Opioid-Related Disorders epidemiology
Abstract: Background: Methadone and buprenorphine are the most prevalent types of opioid maintenance programs in Andalusia. The main objective is comparing the functional status of patients with pharmacological opioid maintenance treatments according to different socio-demographic characteristic, health and disabilities domains and sexual difficulties., Methods: A total of 593 patients from the Andalusia community, 329 were undergoing methadone treatment and 264 were undergoing buprenorphine treatment. The patients were interviewed by socio-demographic and opioid-related variables, assessed by functioning, disability and health domains (WHODAS 2.0.) and for sexual problems (PRSexDQ-SALSEX)., Results: We found significant differences in the socio-demographic and the opioid-related variables as the onset of opioid use, being on previous maintenance programs, opioid intravenous use, the length of previous maintenance programs, polydrug use and elevated seroprevalence rates (HCV and HIV) between the methadone group and the buprenorphine group. Regarding health and disability domains there were differences in the Understanding and communication domain, Getting around domain, Participation in society domain and in the WHODAS 2.0. simple and complex score, favoring buprenorphine-treated patients. The methadone group referred elevated sexual impairments compared with the buprenorphine group. Opioid-related variables as seroprevalence rates, other previous lifetime maintenance program, the daily opioid dosage and the daily alcohol use are the most discriminative variables between both groups. Participation in society variables and sexual problems were the most important clinical variables in distinguishing the methadone group from the buprenorphine group regarding their functional status., Conclusions: The methadone group showed higher prevalence in opioid dependence-related variables, elevated disabilities in participation in society activities and sexual problems compared with the buprenorphine group. This study shows the importance of carry out a functional evaluation in the healthcare follow-up, especially in those areas related with social activity and with sexual problems.
Published: 2021
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37. A Novel Enzyme-Based SPR Strategy for Detection of the Antimicrobial Agent Chlorophene.

Author: Quintanilla-Villanueva GE, Luna-Moreno D, Blanco-Gámez EA, Rodríguez-Delgado JM, Villarreal-Chiu JF, and Rodríguez-Delgado MM
Subjects: Anti-Infective Agents, Carbodiimides analysis, Dichlorophen analysis, Gold, Limit of Detection, Surface Plasmon Resonance, Biosensing Techniques, Dichlorophen analogs & derivatives
Abstract: Chlorophene is an important antimicrobial agent present in disinfectant products which has been related to health and environmental effects, and its detection has been limited to chromatographic techniques. Thus, there is a lack of research that attempts to develop new analytical tools, such as biosensors, that address the detection of this emerging pollutant. Therefore, a new biosensor for the direct detection of chlorophene in real water is presented, based on surface plasmon resonance (SPR) and using a laccase enzyme as a recognition element. The biosensor chip was obtained by covalent immobilization of the laccase on a gold-coated surface through carbodiimide esters. The analytical parameters accomplished resulted in a limit of detection and quantification of 0.33 mg/L and 1.10 mg/L, respectively, fulfilling the concentrations that have already been detected in environmental samples. During the natural river's measurements, no significant matrix effects were observed, obtaining a recovery percentage of 109.21% ± 7.08, which suggested that the method was suitable for the fast and straightforward analysis of this contaminant. Finally, the SPR measurements were validated with an HPLC method, which demonstrated no significant difference in terms of precision and accuracy, leading to the conclusion that the biosensor reflects its potential as an alternative analytical tool for the monitoring of chlorophene in aquatic environments.
Published: 2021
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38. Synthesis, crystal structure, Hirshfeld surface analysis and energy framework calculations of trans -3,7,9,9-tetra-methyl-10-(prop-2-yn-1-yl)-1,2,3,4,4a,9,9a,10-octa-hydro-acridine.

Author: Acelas M, Dugarte-Dugarte A, Romero Bohórquez AR, Henao JA, Delgado JM, and Díaz de Delgado G
Abstract: The title heterocyclic compound, C 20 H 27 N, has been prepared in good yield (72%) via a BiCl 3 -catalyzed cationic Povarov reaction between N -propargyl-4-methyl-aniline and (±)-citronellal. The X-ray single-crystal study indicates that the structure consists of mol-ecules connected by C-H⋯π contacts to produce chains, which pack in a sandwich-herringbone fashion along the b -axis direction. Hirshfeld surface analysis indicates that H⋯H inter-actions dominate by contributing 79.1% to the total surface. Energy frameworks and DFT calculations indicate a major contribution of dispersive forces to the total inter-action energy., (© Acelas et al. 2021.)
Published: 2021
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39. Phytochemical profile and antioxidant activity of extracts of the peruvian peppertree Schinus areira L. from Chile.

Author: Rebolledo V, Otero MC, Delgado JM, Torres F, Herrera M, Ríos M, Cabañas M, Martinez JL, and Rodríguez-Díaz M
Abstract: The Andean tree Schinus areira L. has multiple traditional uses, from the treatment of bronchitis and rheumatic diseases to menstrual cycle regulation and wound healing. With reported hypotensive, analgesic, antitumoral and anti-inflammatory properties, it acts predominantly against diseases related to oxidative stress. This study focuses on the antioxidant activity and phytochemical profile of the extracts of Schinus areira L. Serial extraction of the fruits was performed both by maceration and by Soxhlet. Total phenols and flavonoids were measured using the Folin-Ciocalteu method and AlCl 3 , respectively. In vitro antioxidant activity was determined by FRAP and DPPH. Results were similar for both extraction methods. Primary metabolites detected included carbohydrates, proteins and amino acids; secondary metabolites included tannins, flavonoids, saponins, steroids and triterpenes. Antioxidant activity was confirmed for ethyl acetate, methanolic and aqueous extracts. The methanolic extract had both the highest polyphenol content (>195 mg GAE/ g dry weight) and the highest antioxidant activity [EC 50 > 476 μg/mL; >273 mg AA/g dry weight (DPPH); >301 mg AA/ g dry weight (FRAP)]. The extract does not produce macrophage cytotoxicity in RAW 264.7, which is indicated by an average cytotoxicity of 2% over 24 h. Our study serves as a starting point for future research on the pharmacological properties of Schinus areira L., Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (© 2020 The Authors.)
Published: 2021
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40. Receptor-mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy.

Author: Ohnstad AE, Delgado JM, North BJ, Nasa I, Kettenbach AN, Schultz SW, and Shoemaker CJ
Subjects: Autophagosomes metabolism, Autophagy-Related Protein 7 genetics, Autophagy-Related Protein 7 metabolism, Cell Death, Cluster Analysis, HEK293 Cells, Humans, Intracellular Signaling Peptides and Proteins metabolism, K562 Cells, Lysosomes metabolism, Neoplasm Proteins metabolism, Protein Serine-Threonine Kinases metabolism, Ubiquitin metabolism, Autophagy genetics, Autophagy physiology, Autophagy-Related Proteins genetics, Autophagy-Related Proteins metabolism, Microtubule-Associated Proteins genetics, Microtubule-Associated Proteins metabolism
Abstract: Autophagosome formation requires multiple autophagy-related (ATG) factors. However, we find that a subset of autophagy substrates remains robustly targeted to the lysosome in the absence of several core ATGs, including the LC3 lipidation machinery. To address this unexpected result, we performed genome-wide CRISPR screens identifying genes required for NBR1 flux in ATG7 KO cells. We find that ATG7-independent autophagy still requires canonical ATG factors including FIP200. However, in the absence of LC3 lipidation, additional factors are required including TAX1BP1 and TBK1. TAX1BP1's ability to cluster FIP200 around NBR1 cargo and induce local autophagosome formation enforces cargo specificity and replaces the requirement for lipidated LC3. In support of this model, we define a ubiquitin-independent mode of TAX1BP1 recruitment to NBR1 puncta, highlighting that TAX1BP1 recruitment and clustering, rather than ubiquitin binding per se, is critical for function. Collectively, our data provide a mechanistic basis for reports of selective autophagy in cells lacking the lipidation machinery, wherein receptor-mediated clustering of upstream autophagy factors drives continued autophagosome formation., (© 2020 The Authors. Published under the terms of the CC BY 4.0 license.)
Published: 2020
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41. Deep Learning Models for Health and Safety Risk Prediction in Power Infrastructure Projects.

Author: Ajayi A, Oyedele L, Owolabi H, Akinade O, Bilal M, Davila Delgado JM, and Akanbi L
Subjects: Humans, Risk Factors, United Kingdom, Deep Learning, Occupational Health, Power Plants
Abstract: Inappropriate management of health and safety (H&S) risk in power infrastructure projects can result in occupational accidents and equipment damage. Accidents at work have detrimental effects on workers, company, and the general public. Despite the availability of H&S incident data, utilizing them to mitigate accident occurrence effectively is challenging due to inherent limitations of existing data logging methods. In this study, we used a text-mining approach for retrieving meaningful terms from data and develop six deep learning (DL) models for H&S risks management in power infrastructure. The DL models include DNN classify (risk or no risk), DNN reg1 (loss time), DNN reg2 (body injury), DNN reg3 (plant and fleet), DNN reg4 (equipment), and DNN reg5 (environment). An H&S risk database obtained from a leading UK power infrastructure construction company was used in developing the models using the H2O framework of the R language. Performances of DL models were assessed and benchmarked with existing models using test data and appropriate performance metrics. The overall accuracy of the classification model was 0.93. The average R 2 value for the five regression models was 0.92, with mean absolute error between 0.91 and 0.94. The presented results, in addition to the developed user-interface module, will help practitioners obtain a better understanding of H&S challenges, minimize project costs (such as third-party insurance and equipment repairs), and offer effective strategies to mitigate H&S risk., (© 2019 Society for Risk Analysis.)
Published: 2020
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42. Transferable interactions of Li + and Mg 2+ ions in polarizable models.

Author: Wineman-Fisher V, Delgado JM, Nagy PR, Jakobsson E, Pandit SA, and Varma S
Abstract: Therapeutic implications of Li + , in many cases, stem from its ability to inhibit certain Mg 2+ -dependent enzymes, where it interacts with or substitutes for Mg 2+ . The underlying details of its action are, however, unknown. Molecular simulations can provide insights, but their reliability depends on how well they describe relative interactions of Li + and Mg 2+ with water and other biochemical groups. Here, we explore, benchmark, and recommend improvements to two simulation approaches: the one that employs an all-atom polarizable molecular mechanics (MM) model and the other that uses a hybrid quantum and MM implementation of the quasi-chemical theory (QCT). The strength of the former is that it describes thermal motions explicitly and that of the latter is that it derives local contributions from electron densities. Reference data are taken from the experiment, and also obtained systematically from CCSD(T) theory, followed by a benchmarked vdW-inclusive density functional theory. We find that the QCT model predicts relative hydration energies and structures in agreement with the experiment and without the need for additional parameterization. This implies that accurate descriptions of local interactions are essential. Consistent with this observation, recalibration of local interactions in the MM model, which reduces errors from 10.0 kcal/mol to 1.4 kcal/mol, also fixes aqueous phase properties. Finally, we show that ion-ligand transferability errors in the MM model can be reduced significantly from 10.3 kcal/mol to 1.2 kcal/mol by correcting the ligand's polarization term and by introducing Lennard-Jones cross-terms. In general, this work sets up systematic approaches to evaluate and improve molecular models of ions binding to proteins.
Published: 2020
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43. A Nursing Workforce Initiative: Increasing the Latino/Hispanic BSN Workforce.

Author: Cheshire MH, Cuellar NG, Figueroa-Delgado JM, and Rojas P
Subjects: Humans, Mentoring organization & administration, Peer Group, Resilience, Psychological, United States, Education, Nursing, Baccalaureate organization & administration, Hispanic or Latino statistics & numerical data, Nurses statistics & numerical data
Abstract: Of the 3 million nurses in the United States, only 5.4% of registered nurses are Latinos. This is a grave concern since the U.S. Census' projected increase of Latinos in the United States is expected to be 28% by 2060. In 2010, the Institute of Medicine report recommended a diverse workforce in health care to improve health outcomes. However, the increase in the Latino nursing workforce continues to be low compared to with the population of Latinos in the country. The National Association of Hispanic Nurses and the University of Alabama partnered to increase the number of baccalaureate-prepared registered nurses in the workforce. BAMA-Latino Project (BAMA-L) is a Health Resources and Services Administration-funded program to increase the diversity of registered nurses in the nursing workforce. The purpose of this article is to present the development and implementation of BAMA-L.
Published: 2020
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44. Local Hematoma Block as Postoperative Analgesia in Pediatric Supracondylar Humerus Fractures.

Author: Astacio E, Echegaray G, Rivera L, Otero-Delgado JM, Olivella G, Ramírez N, Ramos-Alconini N, and Foy C
Abstract: Purpose: Supracondylar humerus fracture (SHF) is the most common type of fracture in children. The aim of this study was to evaluate the efficacy of local hematoma block with 0.25% bupivacaine as postoperative pain control in patients with pediatric SHF who underwent closed reduction pin fixation., Methods: We performed an institutional review board-approved, prospective cohort study of 65 patients with SHF treated with closed reduction percutaneous pin fixation. For 6 months, all patients were randomly divided into 2 groups. The treatment group (35 patients) received an intraoperative local hematoma block using 0.25% bupivacaine whereas the control group (30 patients) did not receive a local hematoma block as postoperative pain management adjuvant. After surgery, all patients were prescribed opioid pain medication. To evaluate the efficacy of the hematoma block, postoperative morphine equivalent consumption and the Faces Pain Scale-Revised (FPS-R) survey were blindly recorded during postoperative day 1. Demographic data, surgical details, clinical neurovascular examination during the hospital stay, and complications were also evaluated., Results: Comparison of the control group with the treatment group showed similar morphine equivalent consumption and Face Pain Scale-Revised Survey results. No hematoma block-associated complications were reported., Conclusions: The result of this study do not favor the use of local hematoma block to improve pain control and decrease the need for opioid use on postoperative day 1 in pediatric SHF after patients undergo closed reduction percutaneous pin fixation. These results can lay the foundation for future studies while suggesting new, novel opioid-free pain control strategies in patients with SHF., Type of Study/level of Evidence: Therapeutic II.
Published: 2020
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45. Malignant hyperthermia syndrome: A rare entity.

Author: García-Muro C, Sáenz-Moreno I, Riaño-Méndez B, Gutiérrez-Delgado JM, Valencia-Ramos J, and Esteban-Zubero E
Subjects: Adenoidectomy, Child, Dantrolene therapeutic use, Female, Humans, Anesthetics, Inhalation adverse effects, Malignant Hyperthermia drug therapy, Malignant Hyperthermia etiology, Sevoflurane adverse effects
Abstract: Background: Malignant hyperthermia syndrome is a hereditary pharmacogenetic disorder of skeletal muscle characterized by hypermetabolic state related to the exposure of volatile anesthetic gases or depolarizing muscle relaxants. It is an infrequent entity that occurs in genetically predisposed individuals, with a very low incidence in pediatrics (1 in 10,000-15,000 anesthetic procedures)., Case Report: We report a case of malignant hyperthermia related to exposure to sevoflurane during adenoidectomy surgery in a 6-year-old female. The patient presented with tachycardia, hypercapnia, and hyperthermia, requiring two successive doses of dantrolene sodium administration, with an adequate response to the treatment., Conclusions: Malignant hyperthermia syndrome is a rare condition in pediatric patients that should be detected in early stages since it is essential to initiate the treatment as soon as possible., (Copyright: © 2020 Permanyer.)
Published: 2020
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46. Enantioselective PCCP Brønsted acid-catalyzed aza-Piancatelli rearrangement.

Author: Hammersley GR, Nichol MF, Steffens HC, Delgado JM, Veits GK, and Read de Alaniz J
Abstract: An enantioselective aza-Piancatelli rearrangement has been developed using a chiral Brønsted acid based on pentacarboxycyclopentadiene (PCCP). This reaction provides rapid access to valuable chiral 4-amino-2-cyclopentenone building blocks from readily available starting material and is operationally simple.
Published: 2019
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47. Electrochemical Instrumentation of an Embedded Potentiostat System (EPS) for a Programmable-System-On-a-Chip.

Author: Muñoz-Martínez AI, Peña OIG, Colomer-Farrarons J, Rodríguez-Delgado JM, Ávila-Ortega A, and Dieck-Assad G
Abstract: Under the main features required on portable devices in electrochemical instrumentation is to have a small size, low power consumption, economically affordable and precision in the measurements. This paper describes the development of a programmable Embedded Potentiostat System (EPS) capable of performing electrochemical sensing over system-on-a-chip platforms. Furthermore, the study explains a circuit design and develops some validation of the entire system. The hardware validation is performed by electrochemical experiments such as Double Step Chronoamperometry (DSC), Linear Sweep Voltammetry (LSV) and Cyclic Voltammetry (CV); moreover, a comparison of the experimental signals between a commercial potentiostat and the EPS was done by analysis of errors on the response signal. Results illustrate that the EPS is capable of handling currents in the range of absolute values of 86.44 to 3000 nA and having control voltages in the range of ±2 V. The device can support from 50 to 2000 samples per second. The EPS capabilities were compared with other compact potentiostats. The programmable EPS is an original approach which hugely reduces the hardware complexity and leads the way to create new applications for Point-of-Care or industrial developments with a reusable full electronics module., Competing Interests: The authors declare no conflict of interest. The founding sponsors had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript; or in the decision to publish the results.
Published: 2018
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48. Evaluation of the recombinant antigens B2t and 2B2t, compared with hydatid fluid, in IgG-ELISA and immunostrips for the diagnosis and follow up of CE patients.

Author: Hernández-González A, Sánchez-Ovejero C, Manzano-Román R, González Sánchez M, Delgado JM, Pardo-García T, Soriano-Gálvez F, Akhan O, Cretu CM, Vutova K, Tamarozzi F, Mariconti M, Brunetti E, Vola A, Fabiani M, Casulli A, and Siles-Lucas M
Subjects: Adult, Aged, Aged, 80 and over, Animals, Antigens, Helminth genetics, Cross Reactions, Female, Humans, Immunoassay methods, Immunoglobulin G blood, Male, Middle Aged, Recombinant Proteins genetics, Retrospective Studies, Sensitivity and Specificity, Spain, Young Adult, Antibodies, Helminth blood, Antigens, Helminth immunology, Echinococcosis diagnosis, Echinococcus granulosus immunology, Enzyme-Linked Immunosorbent Assay methods, Recombinant Proteins immunology, Serologic Tests methods
Abstract: Cystic echinococcosis (CE) is one of the most widespread helminthic zoonoses and is caused by the tapeworm Echinococcus granulosus complex. CE diagnosis and monitoring primarily rely on imaging techniques, complemented by serology. This is usually approached by the detection of IgG antibodies against hydatid fluid (HF), but the use of this heterogeneous antigenic mixture results in a variable percentage of false positive and negative results, and has shown to be useless for follow-up due to the long persistence of anti-HF antibodies in cured patients. To improve test performances and standardization, a number of recombinant antigens mainly derived from HF have been described, among them the B2t and 2B2t antigens. The performance of these antigens in the diagnosis and follow up of patients with CE has been so far evaluated on a limited number of samples. Here, we evaluated the performances of tests based on B2t and 2B2t recombinant antigens compared to HF in IgG-ELISA and immunochromatography (IC) for the diagnosis and follow-up of patients with CE in a retrospective cohort study. A total of 721 serum samples were collected: 587 from 253 patients with CE diagnosed by ultrasonography (US), 42 from patients with alveolar echinococcosis and 92 from healthy donors from Salamanca (Spain). The highest overall sensitivity was obtained with HF in ELISA (85.5%), followed by IC containing HF and 2B2t-HF (83.0% and 78.2%, respectively). The lowest sensitivity was obtained with B2t and 2B2t in ELISA (51.8%). The highest specificity was obtained with IC containing 2B2t-HF (100%), and the lowest with HF-ELISA (78.0%). The lowest cross-reactivity with sera from patients with alveolar echinococcosis was detected with the recombinant antigens in ELISA (9.5% - 16.7%) and the highest with the HF-IC (64.3%). The results of B2t and 2B2t-ELISA were influenced by cyst stage, as classified by US according to the WHO-Informal Working Group on Echinococcosis (WHO-IWGE), with low sensitivity for inactive (CE4 and CE5) cysts, and by the drug treatment, with higher sensitivity in patients after drug treatment compared with patients not subjected to drug treatment. The two recombinant antigens in ELISA provided promising results for monitoring patients in follow-up, although their use is limited to patients with positive serology against them at the beginning of the follow-up. Potential biological reasons behind the low sensitivity of the recombinant antigens and possible strategies to enhance the performance of CE serology are discussed., Competing Interests: José Manuel Delgado, Teresa Pardo-García, and Francisco Soriano-Gálvez are employed by Parque Tecnológico de la Salud (see Financial Disclosure). The authors declare no other competing interests exist.
Published: 2018
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49. Chronic Arsenic Exposure Increases Aβ (1-42) Production and Receptor for Advanced Glycation End Products Expression in Rat Brain.

Author: Niño SA, Martel-Gallegos G, Castro-Zavala A, Ortega-Berlanga B, Delgado JM, Hernández-Mendoza H, Romero-Guzmán E, Ríos-Lugo J, Rosales-Mendoza S, Jiménez-Capdeville ME, and Zarazúa S
Subjects: Administration, Oral, Animals, Behavior, Animal drug effects, Disease Models, Animal, Male, Rats, Rats, Wistar, Amyloid beta-Peptides biosynthesis, Arsenic administration & dosage, Arsenic toxicity, Brain drug effects, Brain metabolism, Peptide Fragments biosynthesis, Receptor for Advanced Glycation End Products biosynthesis
Abstract: Chronic arsenic exposure during development is associated with alterations of chemical transmission and demyelination, which result in cognitive deficits and peripheral neuropathies. At the cellular level, arsenic toxicity involves increased generation of reactive species that induce severe cellular alterations such as DNA fragmentation, apoptosis, and lipid peroxidation. It has been proposed that arsenic-associated neurodegeneration could evolve to Alzheimer disease in later life.1,2 In this study, the effects of chronic exposure to inorganic arsenic (3 ppm by drinking water) in Wistar rats on the production and elimination of Amyloid-β (Aβ) were evaluated. Male Wistar rats were exposed to 3 ppm of arsenic in drinking water from fetal development until 4 months of age. After behavioral deficits induced by arsenic exposure through contextual fear conditioning were verified, the brains were collected for the determination of total arsenic by inductively coupled plasma-mass spectrometry, the levels of amyloid precursor protein and receptor for advanced glycation end products (RAGE) by Western blot analysis as well as their transcript levels by RT-qPCR, Aβ (1-42) estimation by ELISA assay and the enzymatic activity of β-secretase (BACE1). Our results demonstrate that chronic arsenic exposure induces behavioral deficits accompanied of higher levels of soluble and membranal RAGE and the increase of Aβ (1-42) cleaved. In addition, BACE1 enzymatic activity was increased, while immunoblot assays showed no differences in the low-density lipoprotein receptor-related protein 1 (LRP1) receptor among groups. These results provide evidence of the effects of arsenic exposure on the production of Aβ (1-42) and cerebral amyloid clearance through RAGE in an in vivo model that displays behavioral alterations. This work supports the hypothesis that early exposure to metals may contribute to neurodegeneration associated with amyloid accumulation.
Published: 2018
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50. Impact of Nutritional Intervention on Length of Hospital Stay and Mortality among Hospitalized Patients with Malnutrition: A Clinical Randomized Controlled Trial.

Author: Cano-Torres EA, Simental-Mendía LE, Morales-Garza LA, Ramos-Delgado JM, Reyes-Gonzalez MM, Sánchez-Nava VM, Barragán-Berlanga AJ, Rangel-Rodríguez I, and Guerrero-Romero F
Subjects: Adult, Aged, Diet, Female, Hospitalization, Humans, Inpatients, Length of Stay, Male, Middle Aged, Nutrition Therapy, Nutritional Status, Risk Factors, Malnutrition diet therapy
Abstract: Objective: The objective of this study was to evaluate the impact of a nutritional intervention on hospital stay and mortality among hospitalized patients with malnutrition., Methods: Hospitalized patients with a diagnosis of malnutrition were enrolled and randomly allocated to either an intervention or control group. Participants in the intervention group received an individualized nutrition plan according to energy and protein (1.0-1.5 g/kg) intake requirements as well as dietary advice based on face-to-face interviews with patients and their caregivers or family members. Individuals in the control group received standard nutritional management according to the Hospital Nutrition Department. Nutritional status and disease severity were assessed using nutritional risk screening. Length of hospital stay was defined by the number of days of hospitalization from hospital admission to medical discharge. Reference to another service or death were criteria for study withdrawal. To evaluate mortality, individuals were followed up for 6 months after hospital discharge. Hospital stay and mortality were the intention-to-treat analysis., Results: A total of 55 patients with an average age of 57.1 ± 20.7 years were included into intervention (n = 28) and control (n = 27) groups, respectively. At basal condition, nutritional status, measured by nutritional risk screening score, was similar between the study groups (4.1 ± 0.8 vs 4.2 ± 1.2, p = 0.6). The average hospital stay was lower in the intervention group compared to the control group (6.4 ± 3.0 vs 8.4 ± 4.0 days, p = 0.03). Finally, the mortality rate at 6 months of follow-up was similar in both groups (hazard ratio [HR] = 0.85; 95% confidence interval [CI], 0.17-4.21)., Conclusions: Results of this study suggest that, in hospitalized patients with malnutrition, nutritional intervention and dietary advice decrease hospital stay but not mortality.
Published: 2017
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