Search

Your search keyword '"Delgado Bolton, Roberto C."' showing total 358 results
Start Over Author "Delgado Bolton, Roberto C."
358 results on '"Delgado Bolton, Roberto C."'

2. Joint EANM/SNMMI procedure guideline for the use of 177Lu-labeled PSMA-targeted radioligand-therapy (177Lu-PSMA-RLT).

Author

Kratochwil, Clemens, Fendler, Wolfgang P, Eiber, Matthias, Hofman, Michael S, Emmett, Louise, Calais, Jeremie, Osborne, Joseph R, Iravani, Amir, Koo, Phillip, Lindenberg, Liza, Baum, Richard P, Bozkurt, Murat Fani, Delgado Bolton, Roberto C, Ezziddin, Samer, Forrer, Flavio, Hicks, Rodney J, Hope, Thomas A, Kabasakal, Levent, Konijnenberg, Mark, Kopka, Klaus, Lassmann, Michael, Mottaghy, Felix M, Oyen, Wim JG, Rahbar, Kambiz, Schoder, Heiko, Virgolini, Irene, Bodei, Lisa, Fanti, Stefano, Haberkorn, Uwe, and Hermann, Ken

Subjects
Humans, Lutetium, Heterocyclic Compounds, 1-Ring, Prostate-Specific Antigen, Dipeptides, Radiopharmaceuticals, Treatment Outcome, Nuclear Medicine, Male, Prostatic Neoplasms, Castration-Resistant, EANM/SNMMI, PSMA, [177Lu]Lu-PSMA-617, Aging, Urologic Diseases, Prostate Cancer, Cancer, Good Health and Well Being, EANM, SNMMI, [Lu-177]Lu-PSMA-617, Other Physical Sciences, Clinical Sciences, Nuclear Medicine & Medical Imaging
Abstract

Prostate-specific membrane antigen (PSMA) is expressed by the majority of clinically significant prostate adenocarcinomas, and patients with target-positive disease can easily be identified by PSMA PET imaging. Promising results with PSMA-targeted radiopharmaceutical therapy have already been obtained in early-phase studies using various combinations of targeting molecules and radiolabels. Definitive evidence of the safety and efficacy of [177Lu]Lu-PSMA-617 in combination with standard-of-care has been demonstrated in patients with metastatic castration-resistant prostate cancer, whose disease had progressed after or during at least one taxane regimen and at least one novel androgen-axis drug. Preliminary data suggest that 177Lu-PSMA-radioligand therapy (RLT) also has high potential in additional clinical situations. Hence, the radiopharmaceuticals [177Lu]Lu-PSMA-617 and [177Lu]Lu-PSMA-I&T are currently being evaluated in ongoing phase 3 trials. The purpose of this guideline is to assist nuclear medicine personnel, to select patients with highest potential to benefit from 177Lu-PSMA-RLT, to perform the procedure in accordance with current best practice, and to prepare for possible side effects and their clinical management. We also provide expert advice, to identify those clinical situations which may justify the off-label use of [177Lu]Lu-PSMA-617 or other emerging ligands on an individual patient basis.

Published
2023

6. Radiotherapy and theranostics: a Lancet Oncology Commission

Author

Abdel-Wahab, May, Giammarile, Francesco, Carrara, Mauro, Paez, Diana, Hricak, Hedvig, Ayati, Nayyereh, Li, Jing Jing, Mueller, Malina, Aggarwal, Ajay, Al-Ibraheem, Akram, Alkhatib, Sondos, Atun, Rifat, Bello, Abubakar, Berger, Daniel, Delgado Bolton, Roberto C, Buatti, John M, Burt, Graeme, Bjelac, Olivera Ciraj, Cordero-Mendez, Lisbeth, Dosanjh, Manjit, Eichler, Thomas, Fidarova, Elena, Gondhowiardjo, Soehartati, Gospodarowicz, Mary, Grover, Surbhi, Hande, Varsha, Harsdorf-Enderndorf, Ekaterina, Herrmann, Ken, Hofman, Michael S, Holmberg, Ola, Jaffray, David, Knoll, Peter, Kunikowska, Jolanta, Lewis, Jason S, Lievens, Yolande, Mikhail-Lette, Miriam, Ostwald, Dennis, Palta, Jatinder R, Peristeris, Platon, Rosa, Arthur A, Salem, Soha Ahmed, dos Santos, Marcos A, Sathekge, Mike M, Shrivastava, Shyam Kishore, Titovich, Egor, Urbain, Jean-Luc, Vanderpuye, Verna, Wahl, Richard L, Yu, Jennifer S, Zaghloul, Mohamed Saad, Zhu, Hongcheng, and Scott, Andrew M

Published
2024
Full Text
View/download PDF

9. Production and regulatory issues for theranostics

Author

Giammarile, Francesco, Paez, Diana, Zimmermann, Richard, Cutler, Cathy S, Jalilian, Amirreza, Korde, Aruna, Knoll, Peter, Ayati, Nayyereh, Lewis, Jason S, Lapi, Suzanne E, Delgado Bolton, Roberto C, Kunikowska, Jolanta, Estrada Lobato, Enrique, Urbain, Jean-Luc, Holmberg, Ola, Abdel-Wahab, May, and Scott, Andrew M

Published
2024
Full Text
View/download PDF

16. Sentinel Lymph Node Methods in Breast Cancer

Author

Giammarile, Francesco, Vidal-Sicart, Sergi, Paez, Diana, Pellet, Olivier, Enrique, Estrada-Lobato, Mikhail-Lette, Miriam, Morozova, Olga, Maria Camila, Navarro Marulanda, Diana Ivonne, Rodríguez Sanchez, Delgado Bolton, Roberto C., Valdés Olmos, Renato A., and Mariani, Giuliano

Published
2022
Full Text
View/download PDF

17. Assessment of the therapeutic efficacy of [177Lu]Lu-PSMA-X compared to taxane chemotherapy in taxane-chemo-naïve patients with metastatic castration-resistant prostate cancer: A systematic review and meta-analysis.

Author

Almeida, Ludmila Santiago, García Megías, Irene, Etchebehere, Elba Cristina Sá Camargo, Calapaquí Terán, Adriana K., Herrmann, Ken, Giammarile, Francesco, Treglia, Giorgio, and Delgado Bolton, Roberto C.

Subjects
CASTRATION-resistant prostate cancer, PROSTATE-specific antigen, PROSTATE cancer patients, MEDICAL sciences, OVERALL survival, BIBLIOGRAPHIC databases, ANDROGEN receptors
Abstract

Introduction and aim: Radioligand therapy (RLT) with 177Lu-labelled prostate specific membrane antigen ([177Lu]Lu-PSMA-X, referring with "PSMA-X" to a generic PSMA chemical compound) inhibitors has emerged as a viable treatment option in metastatic castration resistant prostate cancer patients having previously progressed on taxane and androgen receptor inhibitors. The aim of this study was to perform a systematic review and meta-analysis to assess the therapeutic efficacy of [177Lu]Lu-PSMA-X compared to taxane chemotherapy in taxane-chemo-naïve patients with metastatic castration-resistant prostate cancer. Materials and methods: Searches in several bibliographic databases were made using relevant key words, and articles published up to March 2024 were included. The endpoints included prostate specific antigen (PSA) response rate (RR), progression-free survival, and overall survival. Individual patient data were pooled when feasible. PSA50 was defined as the median proportion of patients achieving at least a 50% decline in serum PSA from baseline. A meta-analysis of the PSA50 response rate (proportion meta-analysis) was performed, generating pooled estimates and 95% confidence intervals (95% CI). Results: From the initially selected 8,414 studies published between 2019 and 2023, 24 were included in the [177Lu]Lu-PSMA-X treated group and 17 in the taxane treated group. Our findings show that [177Lu]Lu-PSMA-X RLT yielded comparable PSA50 responses in taxane-naïve patients versus those receiving taxane chemotherapy, despite considerable study heterogeneity. Notably, the taxane-naïve group had more extensive pretreatment. Conclusions: This meta-analysis combines the largest cohorts of taxane-naïve mCRPC patients treated with [177Lu]Lu-PSMA-X RLT and taxane-treated mCRPC. It underscores similar PSA50 response rates in both groups, suggesting a potential role for [177Lu]Lu-PSMA-X RLT in taxane-naïve patients who cannot or choose not to undergo chemotherapy. [ABSTRACT FROM AUTHOR]

Published
2025
Full Text
View/download PDF

19. Development of nuclear medicine in Africa

Author

Grigoryan, Anna, Bouyoucef, Salah, Sathekge, Mike, Vorster, Mariza, Orellana, Pilar, Estrada, Enrique, Mikhail Lette, Miriam, Morozova, Olga, Pellet, Olivier, Paez, Diana, Delgado Bolton, Roberto C., and Giammarile, Francesco

Published
2022
Full Text
View/download PDF

21. Nuclear Medicine Departments in the Era of COVID-19

Author

Paez, Diana, Mikhail-Lette, Miriam, Gnanasegaran, Gopinath, Dondi, Maurizio, Estrada-Lobato, Enrique, Bomanji, Jamshed, Vinjamuri, Sobhan, El-Haj, Noura, Morozova, Olga, Alonso, Omar, Pellet, Olivier, Orellana, Pilar, Navarro, Maria C., Delgado Bolton, Roberto C., and Giammarile, Francesco

Published
2022
Full Text
View/download PDF

25. EANM guideline on the role of 2-[18F]FDG PET/CT in diagnosis, staging, prognostic value, therapy assessment and restaging of ovarian cancer, endorsed by the American College of Nuclear Medicine (ACNM), the Society of Nuclear Medicine and Molecular Imaging (SNMMI) and the International Atomic Energy Agency (IAEA)

Author

Delgado Bolton, Roberto C., Aide, Nicolas, Colletti, Patrick M., Ferrero, Annamaria, Paez, Diana, Skanjeti, Andrea, and Giammarile, Francesco

Published
2021
Full Text
View/download PDF

30. Response Assessment and Follow-Up by Imaging in Lung Tumours

Author

Larici, Anna Rita, Farchione, Alessandra, Cicchetti, Giuseppe, del Ciello, Annemilia, Mantini, Giovanna, Calapaquí Terán, Adriana K., Delgado Bolton, Roberto C., Kauczor, Hans-Ulrich, Series Editor, Parizel, Paul M., Series Editor, Peh, Wilfred C. G., Series Editor, Brady, Luther W., Honorary Editor, Lu, Jiade J., Series Editor, Beets-Tan, Regina G.H., editor, Oyen, Wim J. G., editor, and Valentini, Vincenzo, editor

Published
2020
Full Text
View/download PDF

31. Response Assessment and Follow-Up by Imaging in Head and Neck Tumours

Author

Vandecaveye, Vincent, Nuyts, Sandra, Delgado Bolton, Roberto C., Kauczor, Hans-Ulrich, Series Editor, Parizel, Paul M., Series Editor, Peh, Wilfred C. G., Series Editor, Brady, Luther W., Honorary Editor, Lu, Jiade J., Series Editor, Beets-Tan, Regina G.H., editor, Oyen, Wim J. G., editor, and Valentini, Vincenzo, editor

Published
2020
Full Text
View/download PDF

32. T-Staging and Target Volume Definition by Imaging in Breast Tumours

Author

Delgado Bolton, Roberto C., Calapaquí Terán, Adriana K., Poortmans, Philip, Kauczor, Hans-Ulrich, Series Editor, Parizel, Paul M., Series Editor, Peh, Wilfred C. G., Series Editor, Brady, Luther W., Honorary Editor, Lu, Jiade J., Series Editor, Beets-Tan, Regina G.H., editor, Oyen, Wim J. G., editor, and Valentini, Vincenzo, editor

Published
2020
Full Text
View/download PDF

34. The requirements of a specialist breast centre

Author

Biganzoli, Laura, Cardoso, Fatima, Beishon, Marc, Cameron, David, Cataliotti, Luigi, Coles, Charlotte E., Delgado Bolton, Roberto C., Trill, Maria Die, Erdem, Sema, Fjell, Maria, Geiss, Romain, Goossens, Mathijs, Kuhl, Christiane, Marotti, Lorenza, Naredi, Peter, Oberst, Simon, Palussière, Jean, Ponti, Antonio, Rosselli Del Turco, Marco, Rubio, Isabel T., Sapino, Anna, Senkus-Konefka, Elzbieta, Skelin, Marko, Sousa, Berta, Saarto, Tiina, Costa, Alberto, and Poortmans, Philip

Published
2020
Full Text
View/download PDF

40. Hybrid Imaging for Tumours of the Chest

Author

Delgado Bolton, Roberto C., Calapaquí Terán, Adriana K., Volterrani, Duccio, editor, Erba, Paola Anna, editor, Carrió, Ignasi, editor, Strauss, H. William, editor, and Mariani, Giuliano, editor

Published
2019
Full Text
View/download PDF

46. Medical Professionalism and Its Association with Dropout Intention in Peruvian Medical Students during the COVID-19 Pandemic.

Author

Hancco-Monrroy, Dante E., Caballero-Apaza, Luz M., Abarca-Fernández, Denices, Castagnetto, Jesus M., Condori-Cardoza, Fany A., De-Lama Moran, Raul, Carhuancho-Aguilar, Jose R., Gutierrez, Sandra, Gonzales, Martha, Berduzco, Nancy, Delgado Bolton, Roberto C., San-Martín, Montserrat, and Vivanco, Luis

Subjects
COVID-19 pandemic, MEDICAL students, MEDICAL teaching personnel, SUBJECTIVE well-being (Psychology), MULTIPLE regression analysis, LONELINESS
Abstract

Background: The COVID-19 pandemic introduced unprecedented challenges to medical education systems and medical students worldwide, making it necessary to adapt teaching to a remote methodology during the academic year 2020–2021. The aim of this study was to characterize the association between medical professionalism and dropout intention during the pandemic in Peruvian medical schools. Methods: A cross-sectional online-survey-based study was performed in four Peruvian medical schools (two public) during the academic year 2020–2021. Medical students, attending classes from home, answered three scales measuring clinical empathy, teamwork, and lifelong learning abilities (three elements of medical professionalism) and four scales measuring loneliness, anxiety, depression, and subjective wellbeing. In addition, 15 demographic, epidemiological, and academic variables (including dropout intention) were collected. Variables were assessed using multiple logistic regression analysis. Results: The study sample was composed of 1107 students (390 male). Eight variables were included in an explanatory model (Nagelkerke-R2 = 0.35). Anxiety, depression, intention to work in the private sector, and teamwork abilities showed positive associations with dropout intention while learning abilities, subjective wellbeing, studying in a public medical school, and acquiring a better perception of medicine during the pandemic showed a negative association with dropout intention. No association was observed for empathy. Conclusions: Each element measured showed a different role, providing new clues on the influence that medical professionalism had on dropout intention during the pandemic. This information can be useful for medical educators to have a better understanding of the influence that professionalism plays in dropout intention. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

50. EANM procedure guidelines for radionuclide therapy with 177Lu-labelled PSMA-ligands (177Lu-PSMA-RLT)

Author

Kratochwil, Clemens, Fendler, Wolfgang Peter, Eiber, Matthias, Baum, Richard, Bozkurt, Murat Fani, Czernin, Johannes, Delgado Bolton, Roberto C., Ezziddin, Samer, Forrer, Flavio, Hicks, Rodney J., Hope, Thomas A., Kabasakal, Levant, Konijnenberg, Mark, Kopka, Klaus, Lassmann, Michael, Mottaghy, Felix M., Oyen, Wim, Rahbar, Kambiz, Schöder, Heiko, Virgolini, Irene, Wester, Hans-Jürgen, Bodei, Lisa, Fanti, Stefano, Haberkorn, Uwe, and Herrmann, Ken

Published
2019
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results