137 results on '"Delannoy V"'
Search Results
2. Correction: An immunogenomic exome landscape of triple positive primary antiphospholipid patients
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Guffroy, A., Jacquel, L., Seeleuthner, Y., Paul, N., Poindron, V., Maurier, F., Delannoy, V., Voegeli, A. C., Zhang, P., Nespola, B., Molitor, A., Apithy, M. J., Soulas-Sprauel, P., Martin, T., Voll, R. E., Bahram, S., Gies, V., Casanova, J. L., Cobat, A., Boisson, B., Carapito, R., and Korganow, A. S.
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- 2024
- Full Text
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3. DRESS syndrome au Bortezomib
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Lagreula, M., primary, Waultier-Rascalou, A., additional, Coget, E., additional, Delannoy, V., additional, Chiriac, A.M., additional, and Demoly, P., additional
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- 2024
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4. 5PSQ-121 A review of the exposure to potentially harmful excipients through oral liquid forms in paediatric inpatients in france
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Bobillot, M, primary, Delannoy, V, additional, Trouillard, A, additional, Kinwoski, JM, additional, and Soulairol, I, additional
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- 2024
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5. Optimisation de la prise en charge de la plaie post-chirurgicale par une équipe pluridisciplinaire : étude pilote de faisabilité
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Richard, M., Delannoy, V., Courrege, J., Chkair, S., and Leguelinel-Blache, G.
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- 2020
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6. Radiological assessment of mandibular invasion in squamous cell carcinoma of the oral cavity and oropharynx
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Bouhir, S., Mortuaire, G., Dubrulle-Berthelot, F., Leroy, X., Deken-Delannoy, V., Rysman, B., Chevalier, D., and Mouawad, F.
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- 2019
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7. Évaluation radiologique de l’envahissement mandibulaire dans les carcinomes épidermoïdes de cavité buccale et d’oropharynx
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Bouhir, S., Mortuaire, G., Dubrulle-Berthelot, F., Leroy, X., Deken-Delannoy, V., Rysman, B., Chevalier, D., and Mouawad, F.
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- 2019
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8. Presence in head and neck cancer multidisciplinary team meeting: The patient's experience and satisfaction
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Chaillou, D., Mortuaire, G., Deken-Delannoy, V., Rysman, B., Chevalier, D., and Mouawad, F.
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- 2019
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9. Présence en réunion de concertation pluridisciplinaire dans les cancers des voies aérodigestives supérieures : vécu et satisfaction du patient
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Chaillou, D., Mortuaire, G., Deken-Delannoy, V., Rysman, B., Chevalier, D., and Mouawad, F.
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- 2019
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10. Les brûlures profondes par agents basiques : évaluation d’une stratégie chirurgicale en deux temps
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Devinck, F., Deveaux, C., Bennis, Y., Deken-Delannoy, V., Jeanne, M., Martinot-Duquennoy, V., Guerreschi, P., and Pasquesoone, L.
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- 2018
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11. Prothèse de hanche et de genou : évaluation prospective du niveau de connaissance des patients, de leur besoin d’information au cours de leur prise en charge, et du transfert d’information par le chirurgien
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Billon, L., Décaudin, B., Pasquier, G., Lons, A., Deken-Delannoy, V., Germe, A.-F., Odou, P., and Migaud, H.
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- 2017
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12. Prospective assessment of patients’ knowledge and informational needs and of surgeon-to-patient information transfer before and after knee or hip arthroplasty
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Billon, L., Décaudin, B., Pasquier, G., Lons, A., Deken-Delannoy, V., Germe, A.-F., Odou, P., and Migaud, H.
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- 2017
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13. IMC et risque de mortalité à un an chez des patients très âgés hospitalisés pour COVID-19 : étude observationnelle
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Putot, A., primary, Guyot, C., additional, Manckoundia, P., additional, and Vanwymelbeke-Delannoy, V., additional
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- 2023
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14. Impact de solutions innovantes et gourmandes sur la prise alimentaire de résidents d’EHPAD pour lutter contre la dénutrition
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Vanwymelbeke-Delannoy, V., primary, Koenig, L., additional, Brasse, C., additional, Benassis, M., additional, Lemaout, E., additional, Guyot, C., additional, Belbaghdadi, F., additional, Jaffal, Z., additional, Masson, C., additional, and Maître, I., additional
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- 2023
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15. La personne âgée en portage de repas : quel statut nutritionnel ?
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Fleury, S., primary, Van Wymelbeke-Delannoy, V., additional, Roux, S., additional, Tronchon, P., additional, and Sulmont-Rossé, C., additional
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- 2022
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16. Prévalence de la dénutrition chez les personnes âgées dépendantes pour leur alimentation
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Claire, S.-R., primary, Maître, I., additional, and Van Wymelbeke-Delannoy, V., additional
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- 2022
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17. Fortifier l’alimentation des personnes âgées : encore trop peu de stratégies efficaces pour lutter contre la dénutrition
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Geny, A., primary, Petitjean, M., additional, Van Wymelbeke-Delannoy, V., additional, and Sulmont-Rossé, C., additional
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- 2022
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18. Intravenous hospital preparations for treatment of Covid19: an inter-laboratory comparison of cisatracurium quantification
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Chennell, P., Marchand, C., Grange, Y., Yessaad, M., Delannoy, V., Merienne, C., Soulairol, I., Institut de Chimie de Clermont-Ferrand (ICCF), Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne (UCA)-Institut national polytechnique Clermont Auvergne (INP Clermont Auvergne), Université Clermont Auvergne (UCA)-Université Clermont Auvergne (UCA), CHU Clermont-Ferrand, and Bonnefoy, Stéphanie
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[SDV] Life Sciences [q-bio] ,[SDV]Life Sciences [q-bio] ,ComputingMilieux_MISCELLANEOUS - Abstract
International audience
- Published
- 2021
19. Relevance and feasibility of a personalized dietary intervention in older people with meals-on-wheels: a randomised controlled pilot trial
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Fleury, S., Sulmont-Rossé, C., Cabanes, H., Perruchaud, M., Roger, A., Lesourd, B., Tronchon, P., Van Wymelbeke-Delannoy, V., Maître, I., Julien, Sabine, Centre des Sciences du Goût et de l'Alimentation [Dijon] (CSGA), Université de Bourgogne (UB)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Université Bourgogne Franche-Comté [COMUE] (UBFC), Saveurs et Vie, Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand (CHU Dijon), and Ecole supérieure d'Agricultures d'Angers (ESA)
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2. Zero hunger ,[SDV.AEN] Life Sciences [q-bio]/Food and Nutrition ,[SDV.MHEP.GEG] Life Sciences [q-bio]/Human health and pathology/Geriatry and gerontology ,[SDV.MHEP.GEG]Life Sciences [q-bio]/Human health and pathology/Geriatry and gerontology ,digestive, oral, and skin physiology ,[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition ,Article ,3. Good health - Abstract
International audience; Objective: The present study aimed at assessing the feasibility and the effectiveness of a personalized dietary intervention in a meals-on-wheels service through a randomized controlled pilot trial. Design: Sixty recipients of home-delivered meals (75% of women; 70-97 years old) were recruited and randomly assigned to a control and an experimental group and followed over a period of 4 months. In the experimental group, the nutritional status (Mini-Nutritional Assessment ? MNA questionnaire), the food intake and the food preferences were measured for each participant. Based on this screening, participants were provided with dietary guidance and follow-up. Those at risk of malnutrition were proposed enriched home-delivered meals. Enrichment was set up considering food preferences of the participants. Results: Looking at the whole sample at baseline, 80% (n=48/60) were at risk of malnutrition. Furthermore, 55% (n=33/60) ate less than 2/3 of their calorie and/or protein recommended allowances. In the experimental group, the intervention led to an increase of protein intakes and to a lower extent of calorie intake. In the control group, no significant changes were observed. Conclusion: To conclude, this study suggests that providing dietary guidance and adding nutrient-dense food to meals while considering food preferences is feasible and may help older beneficiaries of meals-on-wheels to increase calorie and protein intake and improve their nutritional status. However, there is a need to develop products or recipes to enrich the meals of the elderly more efficiently to achieve the recommended allowance.
- Published
- 2020
20. Hypoadiponectinaemia and high risk of type 2 diabetes are associated with adiponectin-encoding (ACDC) gene promoter variants in morbid obesity: evidence for a role of ACDC in diabesity
- Author
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Vasseur, F., Helbecque, N., Lobbens, S., Vasseur-Delannoy, V., Dina, C., Clément, K., Boutin, P., Kadowaki, T., Scherer, P. E., and Froguel, P.
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- 2005
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21. Effect of common polymorphisms in the HNF4α promoter on susceptibility to type 2 diabetes in the French Caucasian population
- Author
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Vaxillaire, M., Dina, C., Lobbens, S., Dechaume, A., Vasseur-Delannoy, V., Helbecque, N., Charpentier, G., and Froguel, P.
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- 2005
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22. PRELEVANCE AND FEASIBILITY OF A PERSONALIZED DIETARY INTERVENTION IN OLDER PEOPLE WITH MEALS-ON-WHEELS: A RANDOMIZED CONTROLLED PILOT TRIAL
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Fleury, S., primary, Sulmont-Rossé, C., additional, Cabanes, H., additional, Perruchaud, M., additional, Roger, A., additional, Lesourd, B., additional, Tronchon, P., additional, Van Wymelbeke-Delannoy, V., additional, and Maître, I., additional
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- 2020
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23. A REVIEW OF THE EXPOSURE TO POTENTIALLY HARMFUL EXCIPIENTS THROUGH ORAL LIQUID FORMS IN PAEDIATRIC INPATIENTS IN FRANCE.
- Author
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Bobillot, M., Delannoy, V., Trouillard, A., Kinwoski, J. M., and Soulairol, I.
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- 2024
- Full Text
- View/download PDF
24. Reconception durable de deux systèmes grandes cultures et légumiers pour réduire de moitié l’utilisation des produits phytosanitaires
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Pottiez, Bruno, Allexandre S,, Grouselle-Labouysse, M., Mollet, A., Petit, K., Bruyère, J., Oste, S., Siméon, F., Delassus, F., Delannoy, V., Louvel, B., Douay, Francis, Werbrouck, Dominique, Siah, A., Halama, Patrice, Chambre Régionale d'Agriculture du Nord-Pas-de-Calais (CRA Nord-Pas-de-Calais), Pôle Légumes Région Nord, Partenaires INRAE, Etablissement Public Local d'Enseignement Agricole (EPLEFPA), Fédération Régionale de Défense contre les Organismes Nuisibles du Nord Pas de Calais (FREDON Nord Pas de Calais), Institut Technique de la Betterave (ITB), Institut Supérieur d'Agriculture de Lille (ISA), and Projet DEPHY EXPE Ecophyto cofinancé par l’Office National de l'Eau et des Milieux Aquatiques (ONEMA) et la Région Hauts-de-France.
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Leviers alternatifs ,Alternative levers ,Integrated protection ,Ecophyto ,Input reduction ,Prophylaxis ,Réduction d’intrants ,Protection intégrée ,[SDV]Life Sciences [q-bio] ,Prophylaxie - Abstract
Ce numéro est constitué d’articles de synthèse des projets DEPHY EXPE publiés à l’occasion du colloque national DEPHY, qui s’est déroulé les 13 et 14 novembre 2018 à la Cité des Sciences et de l'Industrie (Paris). Nous vous invitons à découvrir le bilan et les enseignements des 21 projets conduits sur la période 2012-2017.; National audience; This study, conducted in the framework of the DEPHY EXPE Ecophyto dispositive, over a six-year period, aims at using agronomic and technical levers in order to reduce by 50 % the use of conventional phytopharmaceutical products in two cropping systems (arable and vegetable crops). After five years of experimentation, the majority of the expected technics were used and the application of some levers was analyzed. Some problems without solutions were identified, such as the control of bio-aggressors in canned peas, weeding in onion and modulation of thresholds regarding populations of auxiliaries. Results showed in average a lower performance of IFT50 conditions (reduced by 50% for treatments at the cropping system scale) that varies depending on the considered crop and year. However, the performances obtained are encouraging and can be further improved in order to optimize the benefits of certain levers.; Cette étude, conduite dans le cadre du dispositif DEPHY EXPE Ecophyto, sur une durée de six ans, vise à utiliser des leviers agronomiques et techniques en vue de réduire de 50 % l’utilisation des produits phytopharmaceutiques conventionnels dans deux systèmes de culture (grandes cultures et cultures légumières). Après cinq années d’expérimentation, la majorité des règles de décision ont été appliquées et la faisabilité de certains leviers mis en place a également été analysée. Ont également été identifiés des problèmes non résolus avec la technicité disponible, comme par exemple la maîtrise des bio-agresseurs du pois de conserve, le désherbage de l’oignon et la modulation des seuils de nuisibilité selon les niveaux de populations des auxiliaires. Les résultats mettent en évidence, en moyenne, des niveaux de performance moindres dans la conduite IFT50 (réduction de 50 % des IFT à l’échelle du système), avec des variations selon la culture et l’année considérée. Ces performances sont toutefois encourageantes et peuvent être améliorées afin d’optimiser l’apport de certains leviers.
- Published
- 2018
25. Reconception durable de deux systèmes grandes cultures et légumiers pour réduire de moitié l’utilisation des produits phytosanitaires
- Author
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Allexandre S, Grouselle-Labouysse , M., Mollet, A., Petit, K., Bruyère, J., Oste, S., Simeon, F., Delassus, F., Delannoy, V., Louvel, B., Douay, Françis, Werbrouck, Dominique, Siah, A., Halama, Patrice, and Pottiez, Bruno
- Subjects
Ecophyto ,Réduction d’intrants ,Leviers alternatifs ,Prophylaxie ,Protection intégrée ,Input reduction ,Alternative levers ,Prophylaxis ,Integrated protection - Abstract
Cette étude, conduite dans le cadre du dispositif DEPHY EXPE Ecophyto, sur une durée de six ans, vise à utiliser des leviers agronomiques et techniques en vue de réduire de 50 % l’utilisation des produits phytopharmaceutiques conventionnels dans deux systèmes de culture (grandes cultures et cultures légumières). Après cinq années d’expérimentation, la majorité des règles de décision ont été appliquées et la faisabilité de certains leviers mis en place a également été analysée. Ont également été identifiés des problèmes non résolus avec la technicité disponible, comme par exemple la maîtrise des bio-agresseurs du pois de conserve, le désherbage de l’oignon et la modulation des seuils de nuisibilité selon les niveaux de populations des auxiliaires. Les résultats mettent en évidence, en moyenne, des niveaux de performance moindres dans la conduite IFT50 (réduction de 50 % des IFT à l’échelle du système), avec des variations selon la culture et l’année considérée. Ces performances sont toutefois encourageantes et peuvent être améliorées afin d’optimiser l’apport de certains leviers., This study, conducted in the framework of the DEPHY EXPE Ecophyto dispositive, over a six-year period, aims at using agronomic and technical levers in order to reduce by 50 % the use of conventional phytopharmaceutical products in two cropping systems (arable and vegetable crops). After five years of experimentation, the majority of the expected technics were used and the application of some levers was analyzed. Some problems without solutions were identified, such as the control of bio-aggressors in canned peas, weeding in onion and modulation of thresholds regarding populations of auxiliaries. Results showed in average a lower performance of IFT50 conditions (reduced by 50% for treatments at the cropping system scale) that varies depending on the considered crop and year. However, the performances obtained are encouraging and can be further improved in order to optimize the benefits of certain levers.
- Published
- 2018
26. 4CPS-260 Pre-anaesthesia best possible medication history for orthopaedic surgery-programmed patients
- Author
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Renaudin, A, primary, Delannoy, V, additional, Knight, M, additional, Roux, C, additional, Kinowski, JM, additional, and Richard, H, additional
- Published
- 2019
- Full Text
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27. Prognostics factors of poor functionally response in ranibizumab treatment for diabetic macular edema
- Author
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Jullien, M., primary, Deken-Delannoy, V., additional, and Labalette, P., additional
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- 2015
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28. Molecular and cytogenetic characterisation of a small interstitial de novo 20p13--p12.3 deletion in a patient with severe growth deficit
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Leprêtre F, Claire MONTPELLIER, Delannoy V, Froguel P, Vasseur F, Assemblage et réplication du virus de l'hépatite C (ARVHC), Centre National de la Recherche Scientifique (CNRS), Génétique des maladies multifactorielles (GMM), Université de Lille, Droit et Santé-Centre National de la Recherche Scientifique (CNRS), Section of Genomic Medicine, Imperial College London, Genome Centre, Imperial College London-Hammersmith campus, Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), and Froguel, Philippe
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Male ,MESH: Pedigree ,MESH: Chromosome Deletion ,Chromosomes, Human, Pair 20 ,[SDV.GEN.GH] Life Sciences [q-bio]/Genetics/Human genetics ,White People ,Contig Mapping ,MESH: Chromosomes, Human, Pair 20 ,Humans ,MESH: In Situ Hybridization, Fluorescence ,MESH: Contig Mapping ,Alleles ,Growth Disorders ,In Situ Hybridization, Fluorescence ,MESH: Humans ,MESH: Alleles ,Infant ,MESH: European Continental Ancestry Group ,MESH: Haplotypes ,MESH: Growth Disorders ,MESH: Infant ,MESH: Male ,Chromosome Banding ,Pedigree ,MESH: Karyotyping ,[SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics ,Haplotypes ,Karyotyping ,MESH: Chromosome Banding ,Female ,MESH: Microsatellite Repeats ,Chromosome Deletion ,MESH: Female ,Microsatellite Repeats - Abstract
We report on a small de novo interstitial deletion of the short arm of chromosome 20, 46,XY,del(20)(p12.3p13), in a young boy with hypotonia, moderate development delay, mild facial dysmorphism and severe growth failure. This patient did not show major features of Alagille-Watson Syndrome (AWS) which are common in more proximal 20p deletions. Standard and high resolution chromosome banding analysis revealed an apparent terminal deletion. Nevertheless, using chromosomal fluorescent in situ hybridization (FISH) and molecular analysis with polymorphic markers, we demonstrated that the abnormal chromosome resulted from a de novo interstitial deletion of paternal origin spanning from D20S842 to D20S900 and covering approximately 6 Mb. These findings indicate that a karyotype can lead to insufficient characterization of an apparently terminal deletion, and that one or a few genes in 20p13-->p12.3 bands are important for normal growth.
- Published
- 2002
29. Angioscanographie thoracique au gadolinium en TDM multicoupe du thorax : analyse rétrospective de la qualité image et de la tolérance chez 45 patients évalués antérieurement à la description de la fibrose systémique néphrogénique
- Author
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Smadja, L, primary, Rémy-Jardin, M, additional, Dupuis, P, additional, Deken-Delannoy, V, additional, Devos, P, additional, Duhamel, A, additional, Laffitte, JJ, additional, Dequiedt, P, additional, and Rémy, J, additional
- Published
- 2009
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30. Irradiation en angioscanographie thoracique : comparaison entre la technologie mono et bitube
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Santos Name, C., primary, Rémy-Jardin, M., additional, Dupuis, P., additional, Delannoy, V., additional, Faivre, J.B., additional, Duhamel, A., additional, and Rémy, J., additional
- Published
- 2007
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31. Dissection of an inverted X(p21.3q27.1) chromosome associated with mental retardation
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Leprêtre, F., primary, Delannoy, V., additional, Froguel, P., additional, Vasseur, F., additional, and Montpellier, C., additional
- Published
- 2003
- Full Text
- View/download PDF
32. Étude séquentielle de l'atteinte pulmonaire au cours de la sclérodermie systémique par tomodensitométrie thoracique en haute résolution : À propos de 90 patients
- Author
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Launay, D., primary, Rémy-Jardin, M., additional, Hatron, P.Y., additional, Hachulla, E., additional, Mastora, I., additional, Michon-Pasturel, U., additional, Queyrel, V., additional, Lambert, M., additional, Delannoy, V., additional, and Devulder, B., additional
- Published
- 2002
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33. Tomodensitométrie thoracique en haute résolution chez 90 patients sclérodermiquescorrélation avec le profil clinique, biologique et fonctionnel
- Author
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Launay, D., primary, Rémy-Jardin, M., additional, Hatron, P.Y., additional, Hachulla, E., additional, Mastora, I., additional, Michon-Pasturel, U., additional, Lambert, M., additional, Queyrel, V., additional, Delannoy, V., additional, and Devulder, B., additional
- Published
- 2002
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34. THU0255 A new bone prognostic factor in multiple myeloma (mm): level serum cross-laps (ctx) at diagnosis
- Author
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Duché, A, primary, Leleu, X, additional, Duhamel, A, additional, Delannoy, V, additional, Facon, T, additional, and Brazier, M, additional
- Published
- 2001
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35. Molecular and cytogenetic characterisation of a small interstitial de novo 20p13→p12.3 deletion in a patient with severe growth deficit
- Author
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Leprêtre, F., primary, Montpellier, C., additional, Delannoy, V., additional, Froguel, P., additional, and Vasseur, F., additional
- Published
- 2001
- Full Text
- View/download PDF
36. Dual-source chest CT angiography with high temporal resolution and high pitch modes: evaluation of image quality in 140 patients.
- Author
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Tacelli N, Remy-Jardin M, Flohr T, Faivre JB, Delannoy V, Duhamel A, Remy J, Tacelli, Nunzia, Remy-Jardin, Martine, Flohr, Thomas, Faivre, Jean-Baptiste, Delannoy, Valérie, Duhamel, Alain, and Remy, Jacques
- Abstract
Objective: To evaluate image quality of dual-source computed tomography (CT) angiograms acquired with high temporal resolution and high pitch modes.Methods: Two groups of 70 consecutive patients underwent chest CT angiography with dual-source, single-energy CT, with an 83-ms temporal resolution and a pitch of 2 (group 1) or a pitch of 3 (group 2). Subjective and objective image quality and the diagnostic value were assessed by two radiologists in consensus. The radiation dose was recorded.Results: The image quality was always diagnostic in both groups, rated as excellent in 97% of group 1 (68/70) and 98.5% of group 2 (69/70) examinations. Although no statistically significant difference in subjective image noise was found between the two groups (p = 0.3055), objective noise was found to be statistically higher in group 2 (p < 0.0001). The signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were found to be significantly higher in group 1 than in group 2 (p = 0.0014). The acquisition time was significantly shorter in group 2 than in group 1 (p < 0.0001). The dose-length product was significantly lower in group 2 than in group 1 (p < 0.0001).Conclusion: High temporal resolution and high pitch modes provided standard CT angiographic examinations of excellent quality for thoracic applications in routine clinical practice. [ABSTRACT FROM AUTHOR]- Published
- 2010
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37. Assessment of lobar perfusion in smokers according to the presence and severity of emphysema: preliminary experience with dual-energy CT angiography.
- Author
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Pansini V, Remy-Jardin M, Faivre JB, Schmidt B, Dejardin-Bothelo A, Perez T, Delannoy V, Duhamel A, Remy J, Pansini, Vittorio, Remy-Jardin, Martine, Faivre, Jean-Baptiste, Schmidt, Bernhard, Dejardin-Bothelo, Alexis, Perez, Thierry, Delannoy, Valérie, Duhamel, Alain, and Remy, Jacques
- Abstract
The purpose of the study was to assess pulmonary perfusion on a lobar level in smokers using dual-energy computed tomography (CT). Forty-seven smokers and ten non-smokers underwent a dual-energy multi-detector CT angiogram of the chest that allowed automatic quantification of emphysema and determination of the iodine content at the level of the microcirculation (i.e. "perfusion imaging"). Emphysema was present in 37 smokers and absent in ten smokers. Smokers with an upper lobe predominance of emphysema (n = 8) had: (1) significantly lower attenuation enhancement values in the upper lobes compared with smokers without emphysema; (2) the lobes with the most severe emphysematous changes had a statistically significantly higher percentage of emphysema (p = 0.0001) and lower mean attenuation enhancement values (p = 0.0001) than the ipsilateral lobes with less severe emphysema, matching parenchymal destruction; (3) a correlation was found between the difference in percentage of emphysema between the upper and lower lobes and the difference in attenuation attenuation enhancement values in the corresponding lobes (p = 0.0355; r = -0.54). Regional alterations of lung perfusion can be depicted by dual-energy CT in smokers with predominant emphysema. [ABSTRACT FROM AUTHOR]
- Published
- 2009
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38. Effect of common polymorphisms in theHNF4apromoter on susceptibility to type 2 diabetes in the French Caucasian population.
- Author
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Vaxillaire, M., Dina, C., Lobbens, S., Dechaume, A., Vasseur-Delannoy, V., Helbecque, N., Charpentier, G., and Froguel, P.
- Subjects
DIABETES ,GENETIC polymorphisms ,CAUCASIAN race ,PANCREATIC beta cells ,SOMATIC embryogenesis ,GENE expression - Abstract
Aims/hypothesis: The gene encoding HNF-4α, an orphan nuclear receptor playing critical roles in embryogenesis and metabolism by regulating gene expression in pancreatic beta cells, liver, and other tissues, is localised to chromosome 20q13, where linkage to type 2 diabetes has been shown in multiple studies. As two reports have independently demonstrated a convincing association with variants adjacent to the HNP-4α P2 promoter in Finnish and Ashkenazi Jewish populations, we evaluated their contribution to diabetes risk in the French Caucasian population. Methods: Genotypes for four haplotype tag SNPs were analysed for association with diabetes in a case- control study of 744 unrelated type 2 diabetic patients and 686 normoglycaemic subjects, and for linkage in 148 diabetic families in whom significant linkage to the HNP4α region had been shown. Results: The association seen in the Finnish and Ashkenazi studies for SNPs rs2 144908 and rs 1884614 located within a haplotype block encompassing the beta cell promoter P2 of HNP-4α was not replicated in our study; in French Caucasians the minor allele prevalence was increased in control subjects [odds ratio (OR) 0.80, uncorrected p=0.022 for rs2 144908; OR 0.82 uncorrected p=0.058 for rs1884614]. Furthermore, none of the SNPs tested in the French familial sample was associated with diabetes, nor do they appear to contribute to the linkage. Conclusions/interpretation: None of the previously associated SNPs confer an increased risk for diabetes in French Caucasians. A large meta-analysis of association studies will determine whether there is a consistent association between particular SNPs upstream of HNP-4α and type 2 diabetes in several ethnic groups. [ABSTRACT FROM AUTHOR]
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- 2005
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39. Molecular and cytogenetic characterisation of a small interstitial de novo 20p13→p12.3 deletion in a patient with severe growth deficit.
- Author
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Leprêtre, F., Montpellier, A C., Delannoy, V., Froguel, P., and Vasseur, F.
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MUSCLE hypotonia ,CYTOGENETICS ,GENETICS ,FLUORESCENCE in situ hybridization ,SYNDROMES ,CHROMOSOMES - Abstract
We report on a small de novo interstitial deletion of the short arm of chromosome 20, 46,XY,del(20)(p12.3p13), in a young boy with hypotonia, moderate development delay, mild facial dysmorphism and severe growth failure. This patient did not show major features of Alagille-Watson Syndrome (AWS) which are common in more proximal 20p deletions. Standard and high resolution chromosome banding analysis revealed an apparent terminal deletion. Nevertheless, using chromosomal fluorescent in situ hybridization (FISH) and molecular analysis with polymorphic markers, we demonstrated that the abnormal chromosome resulted from a de novo interstitial deletion of paternal origin spanning from D20S842 to D20S900 and covering approximately 6 Mb. These findings indicate that a karyotype can lead to insufficient characterization of an apparently terminal deletion, and that one or a few genes in 20p13→p12.3 bands are important for normal growth. Copyright © 2002 S. Karger AG, Basel [ABSTRACT FROM AUTHOR]
- Published
- 2001
- Full Text
- View/download PDF
40. POST-INDUCTION MINIMAL RESIDUAL DISEASE ASSESSMENT BY BOTH MULTIPARAMETER FLOW CYTOMETRY AND RT-PCR PREDICTS OUTCOME IN ACUTE MYELOID LEUKEMIA
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Bories, C., Dumezy, F., Nibourel, O., Fouquet, G., Boyle, E. M., Willaume, A., Deken-Delannoy, V., Quesnel, B., Claude Preudhomme, and Berthon, C.
41. 40 EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004
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Veitenhansl, M., Stegner, K., Hierl, F-X, Dieterle, C., Feldmeier, H., Gutt, B., Landgraf, R., Garrow, A. P., Vileikyte, L., Findlow, A., Waterman, C., Boulton, A. J. M., Shankhdhar, K., Shankhdhar, L., Shankhdhar, U., Petrova, N. L., Foster, A. V. M., Edmonds, M. E., Ferraresi, R., Caravaggi, C., Giglio, R., Cavaiani, P., Pogliaghi, I., Sommariva, E., Katz, I. A., Harlan, A., Miranda-Palma, B., Prieto-Sanchez, L., Armstrong, D. G., Bowker, J. H., Mizel, M. S., Cernea, S., Wohlgelernter, J., Kidron, M., Modi, P., Raz, I., Arbit, E., Nosek, L., Kapitza, C., Beckett, P., Gelfand, R., Goldberg, M., Heise, T., Testa, M. A., Turner, R. R., Hayes, J. F., Scranton, R. E., Simonson, D. C., Yang, Y-W, Hsu, Y-J, Naujok, O., Francini, F., Jorns, A., Tiedge, M., Lenzen, S., Abdel-Wahab, Y. H. A., Marenah, L., Orr, D. F., Shaw, C., Flatt, P. R., Chokkalingam, K., Mansell, P. I., Clausen, P., Ekbom, P., Damm, P., Feldt-Rasmussen, U., Nielsen, B., Mathiesen, E. R., Feldt-Rasmussen, B., Dewan, S., Da Silva, N., Ternan, P. Mc, Leong, K. S., Wilding, J. P. H., Asatiani, N., Kurashvili, R., Dundua, M., Shelestova, E., Pagava, K., Ramazashvili, M., Hod, M., Smirnov, S., Petersen, J. L. A., Justesen, T. I., Ringholm Nielsen, L., Muller, C., Hojlund, K., Wensaas, A., Kase, E. T., Aas, V., Rustan, A. C., Thoresen, G. H., Levin, K., Beck-Nielsen, H., Gaster, M., Im, S-S, Kang, S-Y, Kim, S-Y, Ahn, Y-H, Lihn, A. S., Schmoll, D., Werner, T., Kienitz, A., Meyer, M., Barthel, A., Ailett, F., Sutherland, C., Walther, R., Grempler, R., Sasson, S., Reich, R., Tenenbaum, T., Alpert, E., Anfossi, G., Russo, I., Traversa, M., Massucco, P., Mattiello, L., Doronzo, G., Trovati, M., Lally, S., Tan, C. Y., Owens, D., Tomkin, G. H., Porchay, I., Pean, F., Bellili, N., Betoulle, D., Balkau, B., Tichet, J., Marre, M., Fumeron, F., Group D.E.S.I.R., Chatellier, G., Alhenc-Gelas, F., Diabhycar, Study Group, Nichols, G. A., Brown, J. B., Hayes, R. P., Bowman, L., Drexel, H., Saely, C. H., Marte, T., Benzer, W., Langer, P., Hoefle, G., Moll, W., Aczel, S., Karagiannis, E., Lubben, G., Urquhart, R., Edwards, G., Bruce, S., Howlett, H. S. C., Cugnardey, N., Turner, K. C., Park, J-S, Fiedorek, F. T., Avogaro, A., Gallo, A., Pinton, P., Rizzuto, R., Murphy, E., Ceolotto, G., Caterson, I., Guy-Grand, B., Hill, J., Barone, M., Aiello, A., Allochis, G., Borzi, V., Cannata, F., Caronna, S., D Avanzo, A., Elli, R., Formoso, G., Paroli, A., Scardapane, R., Sorichetti, P., Tatti, P., Viviani, G., Santeusanio, F., Italian Repaglinide Study Group, Manzella, D., Grella, R., Abbatecola, A. M., Paolisso, G., Sondergaard, L. G., Monster, T. B. M., Johnsen, S. P., Olsen, M. L., Mclaughlin, J. K., Sorensen, H. T., Lervang, H. H., Rungby, J., Lyssenko, V., Fredriksson, J., Almgren, P., Anevski, D., Orho-Melander, M., Sjogren, M., Tuomi, T., Groop, L., Jaziri, R., Aubert, R., Tuomilehto, J., Hu, G., Jousilahti, P., Peltonen, M., Lindstrom, J., Laina, A., Alevizaki, M., Philippou, G., Souvatzoglou, A., Anastasiou, E., Alba, S., Metcalf, B. S., Voss, L. D., Jeffery, A. N., Wilkin, T. J., Gluimer, C., Colagiuri, S., Vistisen, D., Borch-Johnsen, K., Haynes, A., Bower, C., Bulsara, M. K., Jones, T. W., Davis, E. A., Mortensen, H. B., Hougaard, P., Holl, R., Swift, P., Pociot, F., Knip, M., Hansen, L., Szadkowska, A., Pietrzak, I., Zmyslowska, A., Wyka, K., Bodalski, J., Holl, R. W., Swift, R., Hougaard, R., Gerstl, E-M, Engelsberger, I., Rabl, W., Rosenbauer, J., Grobe, H., Hofer, S. E., Krause, U., DPV-Wiss-Study Group, Dabelea, D., Morgan, T., Pettitt, D. J., Dolan, L., Mayer-Davis, E. J., Pihoker, C., Hillier, T. A., Imperatore, G., Ruggiero, A., Hamman, R. E., Stylianou, A., Tentolouris, N., Perrea, D., Tselepis, A. D., Lourida, E., Kitsou, E., Katsilambros, N., Vedovato, M., Dodesini, A. R., Lepore, G., Tiengo, A., Trevisan, R., Penno, G., Miccoli, R., Pucci, L., Lucchesi, D., Bandinelli, S., Fotino, C., Triscornia, S., Baldassari, E., Del Prato, S., Reboldi, P., Santeusanio, E., Fuller, J., Langham, R. G., Gow, R. M., Zhang, Y., Kelly, D. J., Christensen, P. K., Parving, H-H, Gilbert, R. E., Chibalin, A. V., Zhong, Z., Kotova, O., Davidescu, A., Ehren, I., Ekberg, K., Wahren, J., Wassef, L., Buckley, A. J., Rooney, K. B., Briody, J., Thompson, M., Ozanne, S. E., Thompson, C. H., Chamson-Reig, A., Summers, K., Arany, E. J. R., Hill, D. J., Solerte, S. B., Gazzaruso, C., Locatelli, E., Precerutti, S., Schifino, N., Ferrari, E., Fioravanti, M., Phenekos, C. V., Ginis, A., Fragaki, I., Chalkiadaki, M., Tzioras, C., Powell, L. A., Mcguire, G. M., Jewhurst, V., Trimble, E. R., Rasmussen, B. M., Vessby, B., Uusitupa, M., Berglund, L., Pedersen, E., Riccardi, G., Rivellese, A. A., Tapsell, L., Hermansen, K., Kanwu, Study Group, Da Silva Xavier, G., Rutter, J., Rutter, G. A., Briaud, I. M., Lingohr, M. K., Dickson, L. M., Mccuaig, J. R., Lawrence, J. C., Rhodes, C. J., Wikstrom, J. D., Katzman, S. M., Shirihai, O. S., Yang, J., Deng, S., Wang, X., Hessner, M. J., Wu, J., Wong, R. K., Sukumvanich, S., Markman, J. F., Naji, A., Wolf, B. A., Gao, Z., Rubi, B., Del Arco, A., Satrustegui, J., Maechler, P., Del Guerra, S., Lupi, R., Bugliani, M., Sbrana, S., Torri, S., Boggi, U., Vistoli, F., Mosca, F., Marchetti, P., Rennings, A. J. M., Smits, P., Stewart, M. W., Tack, C. J. J., Li, L., Nystrom, T., Gutniak, M., Ahren, B., Holst, J., Sjoholm, A., Gomes, M. B., Cailleaux, S., Tibirica, E., Albertini, J-P, Chen, H., Mather, R., Valensi, P. E., Chisalita, S. I., Arnqvist, H. J., Kraenkel, N., Adams, V., Linke, A., Gielen, S., Schuler, G., Humbrecht, R., Cipollone, F., Iezzi, A., Fazia, M., Pini, B., Cucurullo, C., Cesare, D., Schmidt, A. M., Mazurek, T., Zang, L. F., Mannion, J., Diehl, J., Martin, J., Martella, A., Zalewski, A., Shi, Y., Otter, W., Winter, M., Doering, W., Standi, E., Schnell, O., Kragelund, C., Kober, L., Faber, J., Hildebrandt, P., Steffensen, R., Pankowska, E., Szypowska, A., Lipka, M., Herwig, J., Scholl-Schilling, G., Bohles, H., Robertson, K. J., Schonle, E., Gucev, Z., Mordhorst, L., Tamer, S. C., Gall, M-A, Ludvigsson, J., Hoogma, R. P. L., Hammond, P. J., Gomis, R., Kerr, D., Bruttomesso, D., Bouter, P., Wiefels, K. J., La Calle, H., Schweitzer, D. H., Pfohl, M., Torlone, E., Krinelke, L. G., 205-Nations Study Group, Conget, I., Storms, F., Rodriguez, J., Leperlier, C., Davies, M., At Lantus, Study Group, Peter, R., Luzio, S. D., Dunseath, G., Miles, A., Hare, B., Backx, K., Pauvaday, V., Owens, D. R., Caselli, A., Marfia, G. A., Battista, C., Veves, A., Spallone, V., Uccioli, L., Gonzalez, J. S., Peyrot, M. F., Rubin, R. R., Leventhal, H., Scheffler, N., Ulbrecht, J. S., Cavanagh, P. R., Boulton, A. J., Perrin, N. A., Oglesby, A., Bastyr, E. J., Ziegler, D., Siekierka-Kleiser, E., Meyer, B., Schweers, M., Selvarajah, D., Wilkinson, I. D., Emery, C. J., Shaw, P. J., Griffiths, P. D., Tesfaye, S., Obrosova, I. G., Arezzo, J., Phillips, K., Fidarestat Study Group, Gribble, F. M., Williams, L., Reimann, F., Iakoubov, R., Whiteside, C., Brubaker, P. L., Acitores, A., Gonzalez, N., Sancho, V., Valverde, I., Villanueva-Penacarrillo, M. L., Martin-Duce, A., Trigo, M. V., Arnes, L., Burkart, V., Ichino, N., Ohashi, A., Klein, B. S., Paxian, S., Schmid, R., Karlsen, A. E., Heding, P. E., Frobose, H., Ronn, S. G., Kruhoffer, M., Orntoft, T. F., Nerup, J., Mandrup-Poulsen, T., Billestrup, N., Cardozo, A. K., Ortis, F., Feng, Y-M, Rasschaert, J., Eylen, F., Storling, J., Herchuelz, A., Eizirik, D. L., Wang, H., Kouri, G., Wollheim, C. B., Ribaux, P., Hammar, E., Parnaud, G., Rouiller, D., Bosco, D., Halban, P., Midthjell, K., Carlsson, S., Grill, V., Lau, C., Farch, K., Glumer, C., Tetens, I., Jorgensen, T., Tillin, T., Forouhi, N., Mckeigue, P., Chaturvedi, N., Zethelius, B., Hales, C. N., Berne, C., Coleman, R. L., Stevens, R. J., Holman, R. R., Christensen, J. O., Sandbak, A., Lauritzen, T., Irwin, N., Gault, V. A., Green, B. D., Harriott, P., O Harte, F. P. M., Bouman, S. D., Urso, B., Brand, C. L., Rolin, B., Ribel, U., Schaffer, L., Maggs, D. G., Ceriello, A., Frias, J. P., Wang, Y., Ruggles, J. A., Kolterman, O. G., Piconi, L., Weyer, C., Want, L. L., Ratner, R. E., Uwaifo, G. I., Thornberry, N. A., Eiermann, G., Kim, D., Lankas, G., Leiting, B., Li, Z., Lyons, K., Petrov, A., Sinha Roy, R., Woods, A., Woods, J., Zhang, B. B., Fisher, M., Moller, D. E., Weber, A. E., Dreyer, M., Bellin, C., Schmitz, V., Roesen, R., Nescheret, A. P., Bose, A. K., Mocanu, M. M., Carr, R. D., Yellon, D. M., Manolopoulos, K., Born, S., Wagner, A., Jeziorska, M., Ben Drief, A., Bashir, M., Tomlinson, D., Malik, R. A., Zeymer, U., Schwarzmaier-D Assie, A., Petzinna, D., Chiasson, J-L, Stratton, I. M., Af Bjorkesten, C-G, Fagerudd, J., Rosengard-Barlund, M., Forsblom, C., Pettersson-Fernholm, K., Waden, J., Saraheimo, M., Ronnback, M., Thorn, L., Groop, P-H, Mollsten, A., Svensson, M., Kockum, I., Rudberg, S., Brismar, K., Dahlquist, G., Hovind, P., Hansen, T. K., Tarnow, L., Thiel, S., Jensen, B. R., Flyvbjerg, A., Kankova, K., Hertlova, M., Krusova, D., Schwenke, S., Ott, J., Thom, S. A. M., Mistry, P., Sjolie, A., Larsen, B., Witt, N., Hughes, A. D., Samira, H. H., Lahiry, S., Howlader, S. R., Parveen, S., Azad Khan, A. K., Clarke, P. M., Gray, A., Stevens, R., Holman, R., Phillips, L., Phillips, P. J., Chittleborough, C., Baldock, K., Taylor, A., North West Adelaide Health Study Team, Davis, W. A., Davis, T. M. E., Knuiman, M. W., Hendrie, D., Worthley, D., Nicolucci, A., Pellegrini, F., Berardis, G., Franciosi, M., Belfiglio, M., Rossi, M. C. E., Sacco, M., Valentini, M., Richardson, C. C., Jones, P., Persaud, S., Hussain, K., Clark, A., Christie, M. R., Gniuli, D., Hribal, M. L., Accili, D., Khan, M., Zervou, S., Cheung, L., Abouna, S., Ifandi, V., Pelengaris, S., Luco, R. F., Ferrer, J., Ma, D., Shield, J. P. H., Dean, W., Leclerc, I., Knauf, C., Burcelin, R., Kelsey, G., Powers, A. C., Shostak, A., Ferrara, N., Poffenberger, G., Jerome, W. G., Brissova, M., Geloneze, S. R., Tambascia, M. A., Pareja, J. C., Chaim, E., Silveira, H. V., Geloneze, B., Ravikumar, B., Carey, P. E., Snaar, J. E., Dheelchand, D., Cook, D. B., Neely, D., Taylor, G., Morris, P. G., Taylor, R., Stears, A. J., Masding, M. G., Wootton, S. A., Sandeman, D. D., Klimes, I., Wein, S., Gasperikova, D., Ukropec, J., Wiernsperger, N., Sebokova, E., Manco, M., Mingrone, G., Granato, L., Greco, A. V., Nanni, G., Castagneto, M., Vidal, H., Calvani, M., Ferrannini, E., Alvarsson, M., Sundkvist, G., Lager, I., Henricsson, M., Berntorp, K., Fernqvist-Forbes, E., Steen, L., Orn, T., Shutler, S., Bianchi-Biscay, M., Rosenstock, J., Sugimoto, D., Strange, P., Stewart, J., Soltes Rak, E., Dailey, G., Kloos, C., Muller, U., Samann, A., Femerling, M., Risse, A., Jecht, M., Haak, T., Garg, R., Lawrence, I. G., Akinsola, M. O., Davies, M. J., Mcnally, P. G., Garber, A. J., Kim, H., Draeger, E., Aydin, L., Sengul, A., Kurklu, A., Ucak, S., Basat, O., Seber, S., Altuntas, Y., Jin, J., Yu, Y., Yu, H., Zhang, X., Mattoo, V., Eckland, D., Widel, M., Duran, S., Fajardo, C., Strand, J., Knight, D., Oakley, D., Tan, M., Sato, A., Nagao, M., Aki, N., Nakagami, T., Iwamoto, Y., Zhou, Z., Li, X., Huang, G., Yan, X., Yang, L., Peng, J., Wang, J., Tan, S., Tang, W., Furnsinn, C., Brunmair, B., Wagner, L., Gras, F., Artwohl, M., Zierhut, B., Waldhausl, W., Shine, B. L., Hopkins, D., Anand, V., Lim, E., Raval, U., Sharp, P., Corder, R., Lipkin, D., Lahiri, A., Bartnik, M., Ryden, L., Ferrari, R., Malmberg, K., Pyorala, K., Simoons, M. L., Standl, E., Soler-Soler, J., Ohrvik, J., Euro Heart Survey Investigators, Bruce, D. G., Starkstein, S. E., Schauer, U. J. W., Astrup, A. S., Pietraszek, L., Nielsen, F. S., Rossing, P., Ali, S., Smidt, U. M., Yokoyama, H., Pavkov, M. E., Knowler, W. C., Bennett, P. H., Nelson, R. G., Lopez-Alba, A., Morcillo, L., Caballero, A., Montoya, L., Jimenez, A., Maceira, B., Lewis, J. B., Ravid, M., Wajman, A., Tadgell, C., Remuzzi, G., Hunsicker, L. G., Wessman, M., Taskinen, M-R, FinnDiane Study Group, Pugliese, G., Amadio, L., Menini, S., Oddi, G., Ricci, C., Iacobini, C., Pricci, F., Sorcini, M., Pesce, C., Migliaccio, E., Giorgio, M., Pelicci, P., Di Mario, U., Lassila, M., Jandeleit-Dahm, K., Seah, K. K., Calkin, A. C., Allen, T. J., Cooper, M. E., Lopes Faria, J. M., Cavakcanti, T. C., Silva, K. C., Ferrari, A. L., Lopes Faria, J. B., Cellek, S., Foxwell, N. A., Cotter, M. A., Cameron, N. E., Tennagels, N., Jordan, H., Stahl, P., Voss, M. D., Welte, S., Werner, U., Lehmann, R., Moeschel, K., Baumgartner, F., Oeckinghaus, A., Beck, A., Weigert, C., Hennige, A., Schleicher, E. D., Haring, H. U., Mussig, K., Staiger, H., Haring, H-U, Natalicchio, A., Laviola, L., Tullio, C., Renna, L., Giorgino, R., Giorgino, F., Falasca, M., Maffucci, T., Park, D., Kang, S., Song, J., Lee, D., Lee, Y., Hariharan, N., Kunselman, L., Gu, L., Sasseville, V., Harrity, T., Cheng, P. T. W., Pratley, R. E., Schweizer, A., Mills, D., Kim, T-H, Song, X-L, Poelje, P. D., Potter, S. C., Dang, Q., Fujitaki, J. M., Linemeyer, D. L., Landau, B. R., Erion, M. D., Pankop, M., Golay, A., Despres, J., Sjostrom, L., Lawlor, D. L., Legg, K. T., Ur, E., Houweling, S. T., Kleefstra, N., Meyboom-De Jong, B., Bilo, H. J. G., Schlomer, G. J., Meyer, G., Kasper, J., Muhlhauser, I., Young, B., Taylor, J., Friede, T., Hollis, S., Mason, J., Long, A., Gambling, T., Pauline, L., Burns, E., New, J., Gibson, M., Betteridge, D. J., Leiter, L. A., Audit, Investigators, Whitty, P. M., Eccles, M. P., Hawthorne, G., Grimshaw, J., Steen, I. N., Vanoli, A., Wood, L., Speed, C., Mcdowell, D., Rewers, M., Maahs, D., Wadwa, R., Eckel, R., Tracy, R., Pfutzner, A., Strotmann, H-J, Schulze, J., Hohberg, C., Pahler, S., Forst, T., Ambery, P. D., Sydall, H., Cooper, C., Dennison, E., Sayer, A. Aihie, Barker, D., Phillips, D., Lalic, N. M., Ostojic, M., Lalic, K., Zamaklar, M., Jotic, A., Ilic, M., Rajkovic, N., Lukic, L., Milicic, T., Verges, B., Zeller, M., Steg, P. G., Beer, J. C., Brisard, C., Brindisi, M. C., Dentan, G., Laurent, Y., Janin-Manificat, L., Makki, H., Ravisy, J., Cottin, Y., Ajjan, R. A., Grant, P. J., Futers, T. S., Brown, J. M., Carter, A. M., Rasmussen, M. S., Bruun, J. M., Pedersen, S. 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42. High resolution computed tomography in fibrosing alveolitis associated with systemic sclerosis
- Author
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Launay D, Remy-Jardin M, Michon-Pasturel U, Mastora I, Hachulla E, Lambert M, Delannoy V, Queyrel V, Duhamel A, Matran R, Pascal de Groote, and Py, Hatron
43. 40(th) EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004
- Author
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S. Artigas, A V Dreval, Mark I. McCarthy, C Watson, Peter H. Bennett, M Quint, Y Ikeda, E Alpert, F Schiele, H Sekihara, Erik Gylfe, P Lowe, J Kuhlmann, Alain Golay, V Longo, Shahidul Alam Khan Akm., L G Mantovani, M Zawodniak-Szalapska, G Winkler, T Harrity, L Virág, U Johne, Kuo S-W., Linda C Tapsell, J Rodriguez, Michel Komajda, K Kankova, Carole A. Cull, M Sporna, E Estilles, U Ribel, M C Spruce, E Buzzigoli, T Prazak, J K McLaughlin, M K Lingohr, M Lim, F Calara, A Siebenhofer, G Meregalli, Roberto Anichini, A D Baron, R Kurashvili, P C Butler, G I Fantus, T. E. De Gooyer, Park Y-M., R. Walther, S Heinrich, Agnieszka Zawiejska, S Mukherjee, Nikolaos Papanas, G Wong, Ian D. Caterson, David M. Maahs, Shuichi Kaneko, Alexandra E. Butler, Francisco Javier Ampudia-Blasco, O N Kong, Attali J-R., C A Hedman, K Oshinyemi, Nicolle Müller, I C Cranston, N Okumus, M V Vlaiculescu, Balasubramanian Ravikumar, W W Cheatham, K Mukasa, K B Biswas, Annunziata Lapolla, Phil McEwan, G Mader, Gilles Chassot, Dragi Anevski, Werner A. Scherbaum, M Donath, C Hesselmann, R A Gandhi, David E. Moller, Ezio Bonifacio, C Garcia, V Ifandi, P Hornnes, Nieuwenhoven Fav., C Puech, S Pérez-Del-Pulgar, Kim S-R., G Hines, C Rubio Terrés, Michael Gaster, N. Hosszufalusi, A Scholze, Andrew A. Young, Stavros Liatis, F Hariri, S Tan, Paul Valensi, Allan E. Karlsen, J Kim, E. Moberg, J Kaiser, L Berman, G Nelson, A Altkrüger, P Kothare, D B Cook, S Doran, G. van Dijk, Shahnaz Shahinfar, Kim C-S., P Stahl, M Manousaki, S Sigrist, S K Lim, M. P. Stern, A Guberti, C Rezzani, J McKenney, Karl Thomaseth, Sofia Carlsson, M Julia, R Brillante, I Rubesova, T Darkow, E Matsumoto, Wendy M. Macfarlane, M Di Martino, G Bardini, Rossella Menghini, D Duhot, E Farcasiu, Annalisa Natalicchio, I Lindner, J Buvat, Christian L. Brand, Harry Dorchy, Iwona Pietrzak, Z T Luo, P Home, M Ekelund, Jesper Gromada, Kristine Færch, F Piarulli, H Kim, R Mentel, Zsuzsanna K. Zsengellér, Dullaart Rpf., Anton Luger, Thomas A. Pearson, V Manicardi, P Rösen, Feng Y-M., R Morganti, Lars Hansen, Demuth H-U., Haruo Kasai, A Shostak, Rudi Steffensen, G Taylor, Markolf Hanefeld, C Santini, E Hamaguchi, Roberto Miccoli, F Storms, M Cooper, Y Lee, Allison E. Aiello, P Smith, T Suehiro, K Treece, M Waluś, Timothy A Welborn, Simone Baltrusch, E Kontela, S Chai, J Crean, H Yokoyama, Johan G. Eriksson, Rafael Hernández Hernández, J Rodríguez-Saldaña, M P Tornero, G Formoso, D. Lovell, E Bingham, A Mylonakis, M Manteghetti, D Fedele, Antonio Martín-Duce, Ralph A. DeFronzo, D Salcedo, Kurt Højlund, Antonio Petrone, Sheu Whh., C Gutierrez, Flavia Pricci, S Kurita, Z G Abbas, M M Benedetti, Philippe A. Halban, Daniel J. Cox, O Ljungkvist, Justine Davies, J Palsgaard, Lars Sjöström, E Bosi, L Janin-Manificat, W. F. Kelly, M. Fernandez, E Colak, O V Mulyarchik, B Kronshage, F Lang, M Erfurth, Takashi Kadowaki, N Jendrike, U Walter, J Wishart, Y. Neye, D Kim, N Furuhashi, M Barsotti, D Florow, L Ke, L Borgquist, N C Jackson, Ffolliott M. Fisher, V Baskar, K Yoshioka, Bryan A. Wolf, G Chabrier, R Skoumal, Livio Luzi, H Kose, I Pharisien, B. Klein, H Winiarska, M C Johnson, L Griffiths, Nonna Kravchun, C Combe, Baptist Gallwitz, J Zdychova, L Skorda, Jorma Ilonen, W Gao, I N Steen, A Terrinoni, P D Ambery, W Kern, C M Kusminski, Cho M-H., Paolo Pozzilli, Louise G. Grunnet, E Schönle, David R Matthews, Robert W. Taylor, Y Cohen, Kim H-S., M P Eccles, N B Tutuncu, D McDowell, Richard M. Bergenstal, K Takamatsu, T Steiner, Jaan Palgi, Valdemar Grill, N Niculescu, G Federici, S Lehto, P. M. McKeigue, M Barone, Michael E. Trautmann, S Smirnov, J Mannion, M Eto, C Rousseau, M Conti, C S Ernest, Antonio Ceriello, D H Schweitzer, Jung E-D., Andreas Festa, Avijit Lahiri, A Shepelkevich, A Murro, A Kollmann, Jonathan R.S. Arch, R Landgraf, Son H-Y., I Engelsberger, E Agardh, S Rodríguez-Mulero, P J Kraml, K Lee, D. F. Du Toit, E Kim, G Fadini, Williams Ajk., Philip Home, M B Antcieferov, C Perlemoine, D Perrea, Song X-L., D Ruggieri, Krister Bokvist, Heidi Sørensen, Bilbao, G Yoshino, J P Taylor, Shen H-M., S M Furier, R Urquhart, J Wohlgelernter, Jianping Weng, T. Baba, Q Hong, C Silva, Castaigne J-P., M Felaco, X X Zhang, M Jaroň, Milla Rosengård-Bärlund, J G Papp, Toshio Miyata, Lervang H-H., Park M-K., I Kinalska, A Long, Oomen Phn., N Kogawa, Ippolita Patrizia Patera, S. Karadeniz, Dinesh Selvarajah, D S Chung, A Wensaas, Richard Imrich, M Recasens, J Ruxer, O Buchea, E Wilpart, S P Stepanenko, Le Ttd., H Ohgawara, Mariaconsuelo Valentini, A Mondok, M Peltonen, Marianne O. Larsen, K Chatzianagnostou, Agneta Ståhle, A L Ferrari, L Bordier, F Maingrette, A Matsuda, G Vukomanovic, Jakob D. Wikstrom, T Yamakita, E Gorostiaga, J Jin, B Gopalan, Heinz Drexel, S Hewitt, Rury R. Holman, C Dieterle, T L Ruchti, N Asatiani, M Sidira, A Iezzi, A J Sommerfield, D Châtenet, M L Olsen, R Bergemann, C Koehler, T L Kuraeva, B Balas, Christian Berne, E Santos-Mazo, G Smith, A Siejka, R Kožnarová, A Mattina, S Sheikh, A Adomeit, M Rasmussen, J. Fagerudd, N Busciantella Ricci, Nuria Vilarrasa, E Hammar, T L Thoms, L Aydın, Ron G. Rosenfeld, A Nikolajuk, R Gos, C L Morgan, H L Yu, D Dheelchand, S Ramrath, N Boudriga, Jerome I. Rotter, C Jahannault, W M Weston, Folke Lindgärde, M Hertlova, D Knight, A Monroy-Mayorga, E Pardini, A Chamson-Reig, B Franke, Janie McCluskey, Joseph Bryan, C Nikolopoulou, Christie M. Ballantyne, Fausto Santeusanio, L Pegoraro, M Lee, A Klimenko, S Jaiveer, K. Pettersson-Fernholm, Michael A. Nauck, A Ekbom-Schnell, G Deferrari, Riccardo Schiaffini, S. Pampanelli, Khan Aka., David Hopkins, Maija Wessman, M Kamarinos, Noh J-H., O Ebisui, K McCarroll, Jeppe Sturis, Peter Nowotny, N Gorbenko, Åke Sjöholm, David G. Maggs, A E Halseth, B Cresci, A A Ortiz-Gress, A Korakovouni, O Matejkova, C E Mogensen, C J Lin, Ramon Gomis, H Seaman, C Granier, Yang C-H., F Assah, O Sanchez, Fausto Machicao, Peter G. Morris, Alberto Ortiz, A Giardinelli, D Bracaglia, A Gonzalo, S Pavlatos, Andreas Lechner, F Canovic, L Sjolind, Allan Vaag, Birgitte Bruun Nielsen, David A. Ziegler, Vito Lampasona, R Gershoni-Baruch, A. Dei Cas, H Renz, E Mena, Matthew Waltham, Kim D-M., H Levanen, D D Mick, Valentina Alexandrovna Peterkova, E Meskhishvili, Sarah Nutland, R Bustani, John R. 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Chipchase, S, Treece, K, Pound, N, Hill, N, Cyganek, K, Mirkiewicz sieradzka, B, Malecki, M, Wolkow, P, Skupien, J, Naskalska, A, Sieradzki, J, Tapp, R, Tonkin, A, Harper, A, Mccarty, D, Söderberg, S, Taylor, H, Chitson, P, Alberti, G, Sheetz, M, Aiello, L, Davis, M, Milton, R, Arora, V, Hu, K, Girach, A, Vignati, L, Tyrberg, M, Melander, A, Lindblad, U, Giannarelli, R, Coppelli, A, Sartini, M, Aragona, M, Fletcher, E, Ninkovic, S, Foster, L, Jones, D, De Gooyer, T, Stitt, A, Vingrys, A, Wilkinson berka, J, Lewandowska, A, Randeva, H, Komorowski, J, Lewandowski, K, Jurowski, P, Sankar, S, Gos, R, Kowluru, R, Odenbach, S, Shinn, S, Agardh, C, Hultberg, B, Segura, R, Fonollosa, A, Berrone, E, Beltramo, E, Solimine, C, Ubertalli, A, Islam, N, Esteve, E, Fernandez, M, Recas, I, Mauri, S, Biarnes, F, Junca, E, Fernádez real, J, Rössner, S, Stenlof, K, Levy, B, Perry, B, Fitchet, M, Chrysos, G, Kamaratos, A, Lepeniotis, G, Kokkoris, S, Varytimiadis, K, Stasini, F, Mikros, S, Gianneli, D, 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S, Choi, D, Kim, N, Matsumoto, S, Suetsugu, M, Matsutomo, R, Pisarczyk wiza, D, Banaszak, A, Wysocki, H, Usui, H, Shikata, K, Okada, S, Ogawa, D, Yozai, K, Kido, Y, Nagase, R, Ohga, S, Tone, A, Sasaki, M, Wada, J, Unno, Y, Horiuchi, S, Mclennan, S, Kamarinos, M, Waltham, M, Dy, V, Yue, D, Zdychova, J, Komers, R, Cresci, B, Giannini, S, Manuelli, C, Giunti, S, Pinach, S, Ianni Palarchio, A, Arnaldi, L, Vittone, F, Camussi, G, Cavallo Perin, P, Gruden, G, Marshall, S, Jones, S, White, K, Brizzi, M, Dentelli, P, Rosso, A, Calvi, C, Gambino, R, Cassader, M, Salvidio, G, Deferrari, G, Pegoraro, L, Pagano, G, Cavallo perin, P, Oates, R, Ellery, C, Beebe, D, Coutcher, J, Qian, Y, Lowe, V, Appleton, T, Raunig, D, O'Neil, S, Mylari, B, Amazonas, R, Fujita, A, Doi, A, Matsuno, S, Okamoto, K, Matsumoto, E, Furuta, H, Nishi, M, Tsuno, T, Taniguchi, H, Bessho, H, Wasén, E, Isoaho, R, Mattila, K, Vahlberg, T, Kivelä, S, Irjala, K, Rigalleau, V, Lasseur, C, Perlemoine, C, Barthes, N, Raffaitin, C, 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Rodriguez rosas, H, Peiró martinez, I, Macías batista, A, Harte, A, Rodriguez cuenca, S, Valsamakis, G, Chetty, R, Anderson, L, Roca, P, Matyka, K, Lasalle, J, Hershon, K, Berman, L, Gibson, E, Gillen, D, Maroni, J, Simmons, D, Hiukka, A, Forder, P, Leinonen, E, Hilden, H, Fruchart, J, Keech, A, Farnier, M, Freeman, M, Macdonell, G, Perevozskaya, I, Mitchel, Y, Gumbiner, B, Didangelos, T, Athyros, V, Mikhailidis, D, Papageorgiou, A, Bouloukos, V, Pehlivanidis, A, Symeonidis, A, Elisaf, M, Mckenney, J, Insull, W, Lewin, A, Maccubbin, D, Kush, D, Schuster, H, Barter, P, Stender, S, Bonnet, J, Morrell, J, Watkins, C, Kallend, D, Stalenhoef, A, Ballantyne, C, Murin, J, Tonstad, S, Rose, H, Wilpshaar, W, Jenkins, A, Karschimkus, C, Dragicevic, G, Rowley, K, Wolthers, T, Best, J, Voet, B, Murdoch, S, Marcovina, S, Brunzell, J, Caparevic, Z, Kostic, N, Ilic, S, Sartore, G, Piarulli, F, Cantaro, S, Reitano, R, Fiore, C, Marin, R, Bassan, S, Manzato, E, Fedele, D, Solini, A, Santini, E, Thornalley, P, Babaei jadidi, R, Karachalias, N, Kupich, C, Ahmed, N, Fowler, A, Baker, A, Starczynski, J, O'Hare, P, Szepietowska, B, Szelachowska, M, Puch, U, Glebocka, A, Quinn, D, Mcternan, C, Bonser, R, Idzior walus, B, Woźniakiewicz, E, Dimitriou, K, Apostolou, O, Kontela, E, Devangelio, E, Gould, E, Serri, O, Roussin, A, Buithieu, J, Mamputu, J, Renier, G, Giordanetti, S, De Amici, E, Poggi, G, Turpini, C, Fratino, P, Garzaniti, A, Banu, I, Paries, J, Roman, G, Negrean, M, Bala, C, Nita, C, Kistorp, C, Gustafsson, F, Chong, A, Lip, G, Galatius, S, Ari, N, Sahilli, M, Ceylan isık, A, Ozansoy, G, Karasu yilmaz, C, Matteucci, E, Rosada, J, Pallini, M, Evangelista, I, Cassetti, G, Giusti, C, Giampietro, O, Capaldo, B, Galderisi, M, Cicala, S, Turco, A, Imbroinise, A, Nosso, G, D'Errico, A, De Divitiis, O, Klimontov, V, Korolyova, E, Jeltova, L, Bondar, I, Tarkun, I, Arslan, B, Canturk, Z, Tarkun, P, Agacdiken, A, Komsuoglu, B, Méneveau, N, Pierre justin, E, Alsayed, M, Sabbah, R, Paulin, S, Marcu, S, Tauveron, I, Zimmermann, C, Schiele, F, Seronde, M, Vautrin, P, Lusson, J, Thieblot, P, Bernard, Y, Mistry, A, Pye, M, Peovska, I, Maksimovic Pavlovic, J, Vavlukis, M, Pop Gorceva, D, Bosevski, M, Scognamiglio, R, Negut, C, De Kreutzenberg, S, Madonna, R, De Caterina, R, Willerson, J, Geng, Y, Vahsen, S, Ledwig, D, Ramrath, S, Frantz, S, Schmidt, I, Calvillo, L, Dienesch, C, Elbing, I, Bischoff, H, Ertl, G, Bauersachs, J, Davydov, A, Mkrtum'Yan, A, Baranova, L, Ikeda, Y, Suehiro, T, Osaki, F, Ota, K, Arii, K, Kumon, Y, Hashimoto, K, Doney, A, Morris, A, Palmer, C, Byun, S, Doo, H, Pagnin, E, Calo, L, Fadini, G, Kubaszek, A, Chai, S, Chai, Q, Rasmussen, L, Ledet, T, Wogensen, L, Lengyel, C, Varró, A, Virág, L, Magyar, J, Bíró, T, Jost, N, Skoumal, R, Nánási, P, Tóth, M, Horkay, F, Papp, J, Zacharopoulou, O, Athanaselis, S, Tsokos, N, Doupis, J, Psallas, M, Cokkinos, D, Pavlatos, S, Liatis, S, Akhobadze, T, Dzneladze, L, Samarguliani, I, Taskiran, M, Rasmussen, V, Jensen, G, Fisher, A, Petrovsky, N, Srikusalanukul, W, Budge, M, Trifunovic zamaklar, D, Zivkovic, M, Jelic, V, Vukomanovic, G, Ristic, A, Seferovic, P, Costa, J, Duarte, S, Manley, S, Sailesh, S, Venkataraman, A, Haider, Y, Groza, I, Oprean, M, Ardelean, A, Morosanu, A, Darkow, T, Vanderplas, A, Mamas, M, Mcelduff, P, Burns, J, Edwards, R, Fitchet, A, Young, R, Gibson, J, Lichiardopol, R, Niculescu, N, Totora, A, Pencea, C, Tomescu, I, Cinteza, M, Manicardi, V, Coscelli, C, Navazio, A, Catellani, E, Michelini, M, Dall'Asta, D, Guberti, A, Piazza, A, Gasparini, E, Pantaleoni, M, Guiducci, U, Manari, A, Sejil, S, Janand delenne, B, Avierinos, J, Habib, G, Labastie, N, Vague, P, Lassmann vague, V, Luźniak, P, Tatoń, J, Wojciechowska Luźniak, A, Zairis, M, Lyras, A, Patsourakos, N, Tsirimbis, V, Foussas, S, Lupón, J, Urrutia, A, Herreros, J, González, B, Coll, R, Altimir, S, Prats, M, Valle, V, Abreu padí, C, Rábago, G, Ivanova, L, Brasacchio, D, Harno, E, Keenan, A, Li, H, Lu, Z, Ke, L, Liu, H, Jeong, I, Chae, M, Choi, M, Yoo, H, Kim, C, Yun, M, Na, M, Kang, Y, Kong, O, Son, S, Kim, I, Tanaka, N, Hosoi, M, Matsuyama, Y, Fukumoto, M, Yamakita, T, Yoshioka, K, Ishii, T, Sato, T, Fujii, S, Aoki, T, Shibata, T, Mizutani, N, Suzuki, J, Fowelin, J, Samuelsson, P, Brandrup wogsen, G, Okumura, K, Tokmakova, A, Staroverova, D, Antcieferov, M, Shutichina, I, Kuntchevich, G, Vriesendorp, T, Morélis, Q, Legemate, D, Schaper, F, Mainas, E, Gkioulmpasanis, I, Panagiotou, I, Vassilikos, G, Skorda, L, Sidira, M, Christoforidou, M, Alaveras, A, Artikis, V, Evdemon, E, Lechleitner, M, Koch, T, Ebenbichler, C, Sturm, W, Moretti, L, Moruzzo, D, Boldrini, E, Pandolfo, C, Kameyama, M, Iwasa, R, Cho, M, Nam, J, Huh, K, Kaplar, M, Paragh, G, Erdei, A, Csongradi, E, Garai, I, Varga, J, Galuska, L, Udvardy, M, Higa, M, Kaneko, Y, Hiroi, N, Koziarska, D, Nowacki, P, Majkowska, L, Luzniak, P, Wojciechowska luźniak, A, Tushuizen, M, Nieuwland, R, Snoeck, D, Sturk, A, Diamant, M, Aguiar, L, Bahia, L, Villela, N, Laflor, C, Conde, C, Bottino, D, Dorigo, D, Bouskela, E, Pu, S, Luo, Z, Lam, K, Dan, Q, Xu, A, Shen, J, Cheng, K, Xu, J, Thamer, C, Stefan, N, Haap, M, Heller, E, Tschritter, O, De Prado, A, Ortiz, A, Ybarra, J, Gich, I, Pou, J, Ehren, M, Roggenland, D, Reinsen, B, Klein, H, Rittig, K, Stock, J, Kocher, B, Balletshofer, B, Shon, H, Chung, D, Nakatani, Y, Matsuhisa, M, Kaneto, H, Hatazaki, M, Yoshiuchi, K, Katakami, N, Kawamori, D, Ohtoshi, K, Sakamoto, K, Matsuoka, T, Ozawa, K, Ogawa, S, Hori, M, Yamasaki, Y, Zitouni, K, Harry, D, Nourooz zadeh, J, Earle, K, Olesen, P, Franco, L, Corvaja, C, Semplicini, A, Ceylan işık, A, Arı, N, Rösen, P, Lee, I, Park, K, Jung, E, Shin, D, Jo, S, Obuobie, K, Prakash, P, Hanna, F, Lazarus, J, Varadhan, L, Gurushankar, J, James, D, Sheikh, S, Gaede, P, Zou, D, Vilarrasa, N, Perez maraver, M, Mena, E, Perez, D, Setti, G, Buckingham, R, Urbančič, V, Stefanovska, A, Bernjak, A, Ažman juvan, K, Kocijančič, A, Glowania, A, Filters, T, Fosmark, D, Torjesen, P, Kilhovd, B, Berg, T, Sandvik, L, Hanssen, K, Mentink, C, Donchenko, G, Stepanenko, S, Maingrette, F, Deng, H, Lindenmair, A, Freudenthaler, A, Baumgartner parzer, S, Nizheradze, K, Khoruzhenko, A, Tronko, N, Sheu, W, Ou, H, Shen, H, Lin, T, Wu, H, Yang, C, Mogylnytska, L, Schmoelzer, I, Davies, J, Band, M, Struthers, A, Prázný, M, Škrha, J, Kasalová, Z, Neelotpol, S, Jahan, P, Kauschke, S, Harrop, C, Schäfer, A, Widder, J, Eigenthaler, M, Walter, U, Uchimura, I, Ikebukuro, M, Kaibara, M, Hirata, M, Helal, R, Pervin, F, Yang, X, Jansson, P, Nagaev, I, Jack, M, Carvalho, E, Sunnerhagen, K, Cam, M, Cushman, S, Smith, U, Creely, S, Farmer, J, Gustafson, B, Kusminski, C, Krusinova, E, Wohl, P, Klementova, M, Lanska, V, Mcdougall, C, Kelly, I, Abbas, Z, Lutale, J, Archibald, L, Karunajeewa, H, Stingemore, N, Stuccio, G, Mcgechie, D, Muller, L, Hak, E, Goudzwaard, W, Montorsi, F, Homering, M, Sprenger, K, Goldstein, I, Asnaghi, V, Ferrari, G, Rastaldi, M, Gabellini, D, Dell'Antonio, G, Maestroni, A, Ruggieri, D, Luzi, L, Piemonti, L, Zerbini, G, Anafaroglu, I, Tutuncu, N, Sultana, M, Siddiqua, N, Iwasaki, T, Nakajima, A, Yoneda, M, Mukasa, K, Tanaka, S, and Sekihara, H
- Subjects
0303 health sciences ,medicine.medical_specialty ,business.industry ,EASD ,Endocrinology, Diabetes and Metabolism ,Human physiology ,medicine.disease ,03 medical and health sciences ,0302 clinical medicine ,Diabetes mellitus ,Family medicine ,Internal Medicine ,Medicine ,business ,030217 neurology & neurosurgery ,030304 developmental biology - Published
- 2004
44. Factors influencing participation and regular attendance in a program combining physical activity and nutritional advice for overweight and obese pregnant women.
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Lelorain S, Deruelle P, Béhal H, Machet E, Thiblet M, Lengagne-Piedbois C, Deken-Delannoy V, and Pigeyre M
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- Humans, Female, Pregnancy, Adult, Prospective Studies, Feeding Behavior psychology, Prenatal Care methods, Health Behavior, Exercise, Obesity therapy, Overweight therapy, Pregnancy Complications
- Abstract
Background: Educational programs incorporating physical activity (PA) sessions and nutritional workshops have demonstrated potential benefits for overweight and obese pregnant women. However, participation in such programs remains challenging. This prospective study aimed to investigate the factors influencing participation and regular attendance, while examining changes in health behaviors, along with obstetric and neonatal outcomes., Methods: Pregnant women with at 12-22 weeks' gestation a BMI ≥ 25 kg/m2 were invited to join an educational program combining three nutritional workshops conducted in groups and 12 weekly PA sessions. They self-selected their participation into the program. Regardless of program uptake and regularity of attendance, the women's PA levels, eating behaviors, and affectivity were assessed using validated questionnaires at 20-24 weeks, 32-34 weeks, and postpartum. A multivariable logistic regression model was used to determine the factors influencing participation., Results: Of the 187 women enrolled in the study, 61.5% agreed to participate in the program. Of these, only 45% attended six or more sessions (regardless of the nature of sessions, i.e. nutritional workshops and/or PA sessions), while only 8.7% attended six or more PA sessions. Participation was associated with higher rates of problematic eating behaviors and lower PA levels at baseline, while regular attendance was mainly associated with higher household incomes. No significant difference was observed between participants and non-participants in terms of changes in eating behaviors, PA levels, or affectivity. However, at the 32-34 week visit, regular participants displayed a higher change in positive affectivity, but unexpectedly also in cognitive restraint, than non-regular participants, a difference that did not persist at postpartum., Conclusion: The educational program combining nutrition and PA was shown to be safe. Women facing challenges related to health behavior displayed a willingness to sign up for the program, but tailored interventions addressing their individual challenges are needed to improve attendance. Accordingly, four recommendations are proposed for the design of future interventions., Trial Registration: ClinicalTrials.gov; Identifier: NCT02701426; date of first registration: 08/03/2016., (© 2024. The Author(s).)
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- 2024
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45. Older adults' acceptability of and preferences for food-based protein fortification in the UK, France and Norway.
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Smith R, Methven L, Clegg ME, Geny A, Ueland Ø, Synnøve Grini I, Helgesdotter Rognså G, Maitre I, Brasse C, Van Wymelbeke-Delannoy V, and Sulmont-Rossé C
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- Humans, Aged, Aging, France, United Kingdom, Food, Fortified, Nutritional Status
- Abstract
Research suggests that as we age, protein intake, recognised as vital for combating negative health outcomes, consistently falls below recommendations in older adults. Decreased food intake, combined with age-related eating complications is a major determinant of this protein undernutrition. If nutritional interventions are to be effective and sustainable, they must enable eating pleasure, cater for personal preferences and be adaptable to different eating patterns. As such, we aimed to identify successful strategies for at-home protein-fortification to empower older adults to take a personalised approach to their nutrition, without requiring a large behavioural change. To explore healthy older adults' (age 70+) acceptability and preferences for at-home protein fortification, European project Fortiphy led discussions with older adults (n = 37) and caregivers of older adults (n = 15) to develop high-protein recipes, which were then utilised in a home-use trial with healthy older adults (n = 158). Each fortified recipe was paired with a questionnaire to rate the ease of preparation and liking, and an end-of-study questionnaire was provided to capture overall opinions and preferences. The uniqueness of this study is that the protein fortified recipes were prepared and tested by older adults themselves, in their own homes. Findings showed that older adults were unaware of the importance of protein in ageing and did not have a desire to fortify their foods at present. Yet, they were positive regarding the concept and highlighted the importance of taste, familiar ingredients, and preferred preparation methods. Cultural preferences across countries were identified as having the most influence on the liking of fortified meals. This study also indicated a need for increased awareness of protein requirements to influence the motivation to use fortification., Competing Interests: Declaration of competing interest The authors have no conflicting or competing interests to declare., (Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.)
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- 2024
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46. Association of body mass index with long-term outcomes in older adults hospitalized for COVID-19: an observational study.
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Putot A, Guyot C, Manckoundia P, and Van Wymelbeke-Delannoy V
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- Humans, Male, Aged, Aged, 80 and over, Female, Body Mass Index, SARS-CoV-2, Obesity complications, Obesity epidemiology, Risk Factors, Retrospective Studies, COVID-19 complications
- Abstract
Both underweight and obesity have been associated with poor prognosis in COVID-19. In an older populations of patients hospitalized for SARS-CoV-2 infection, we aimed to evaluate the association between body mass index (BMI) and short and long-term prognosis. Among 434 consecutive patients aged ≥ 70 years and hospitalized for suspected COVID-19 at a university hospital, 219 patients (median age of 83 years, 53% male) testing positive for COVID-19 and for whom BMI was recorded at admission, agreed to participate. Among them, 39 had a BMI < 20 kg/m
2 , 73 had a BMI between 20 and 24.9 kg/m2 and 107 had a BMI ≥ 25 kg/m2 . After adjustment for confounders, BMI < 20 kg/m2 was associated with a higher risk of one-year mortality (hazard ratio (HR) [95% confidence interval]: 1.75 [1.00-3.05], p = 0.048), while BMI ≥ 25 kg/m2 was not (HR: 1.04 [0.64-1.69], p = 0.9). However, BMI was linearly correlated with both in-hospital acute respiratory failure (p = 0.02) and cardiovascular events (p = 0.07). In this cohort of older patients hospitalized for COVID-19, low BMI, rather than high BMI, appears as an independent risk factor for death after COVID-19. The pathophysiological patterns underlying this excess mortality remain to be elucidated., (© 2024. The Author(s).)- Published
- 2024
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47. Hereditary neuropathy associated with liability to pressure palsies: a 24-year experience with carpal and cubital tunnel surgery.
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François T, Davion JB, Deken-Delannoy V, Chantelot C, and Saab M
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- Humans, Retrospective Studies, Pain Measurement, Paralysis, Upper Extremity, Carpal Tunnel Syndrome surgery
- Abstract
The aim of this single-centre retrospective study was to evaluate the outcomes of carpal tunnel release surgery in patients with hereditary neuropathy with pressure palsies (HNPP). The secondary aims were to identify prognostic factors for the outcome of carpal tunnel release and to assess the outcome of cubital tunnel release. Our primary hypothesis was postoperative improvement. In total, 18 patients (26 carpal tunnel releases) with at least one symptomatic carpal tunnel syndrome were included. At a median follow-up of 8.5 years, more than 73% of the patients were satisfied with the results. The visual analogue scale (0 to 10) for discomfort decreased by 2.2 points ( p < 0.001). The Boston Carpal Tunnel Questionnaire symptom severity scale decreased by 1.3 points ( p < 0.001). The decrease in the Functional Status Scale was not significant. No significant prognostic factor for outcome was identified. A total of 12 patients also underwent cubital tunnel release, and three patients underwent just this procedure (23 procedures). Despite the lack of preoperative data, cubital tunnel release provided encouraging results. Level of evidence: III., Competing Interests: Declaration of conflicting interestsThe authors declare no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
- Published
- 2024
- Full Text
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48. Potentially Harmful Excipients: State of the Art for Oral Liquid Forms Used in Neonatology and Pediatrics Units.
- Author
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Bobillot M, Delannoy V, Trouillard A, Kinowski JM, Sanchez-Ballester NM, and Soulairol I
- Abstract
The pediatric population exhibits an important age-dependent heterogeneity in pharmacokinetics and pharmacodynamics parameters, resulting in differences in drug efficacy and toxicity compared to the adult population, particularly for neonates. Toxicity and efficacy divergences have been studied for active molecules, but the impact on the pharmacological parameters of excipients remains less well known. To fill this lack of knowledge, several initiatives have been started to gather information on the specific toxicity of excipients, such as the KIDS list or the STEP database. In order to contribute to this much-needed action, in this work, a compilation of the 219 formulations of oral liquid forms prescribed in pediatrics and neonatology units was established based on the summary of product characteristics. Then, for excipients found in more than 10% of the analyzed formulations, a review of their toxicity data was carried out using the STEP database. Finally, for a selection of 10 frequently used liquid forms, the amounts of excipients administered daily were calculated based on the recommended posology in the Summary of Product Characteristics (SPC) and compared with the recommended daily limits proposed by the European Medicine Agency. Pediatrics-adapted formulations are still rare, and it is not always possible to find safe alternatives to drugs containing excipients of interest.
- Published
- 2024
- Full Text
- View/download PDF
49. Fused Deposition Modelling 3D printing and solubility improvement of BCS II and IV active ingredients - A narrative review.
- Author
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Roche A, Sanchez-Ballester NM, Bataille B, Delannoy V, and Soulairol I
- Subjects
- Solubility, Drug Liberation, Printing, Three-Dimensional, Biological Products
- Abstract
In the field of pharmaceutical research and development, Fused Deposition Modelling (FDM) 3D printing (3DP) has aroused growing interest within the last ten years. The use of thermoplastic polymers, combined with the melting process of the raw materials, offers the possibility of manufacturing amorphous solid dispersions (ASDs). In the pharmaceutical industry, the formulation of an ASD is a widely used strategy to improve the solubility of poorly soluble drugs (classified by the Biopharmaceutical Classification System (BCS) as class II and IV). In this review, an analysis of studies that have developed a FDM printed form containing a BCS class II or IV active substance was performed. The focus has been placed on the evaluation of the solid state of the active molecules (crystalline or amorphous) and on the study of their dissolution profile. Thus, the aim of this work is to highlight the interest of FDM 3DP to induce the amorphisation phenomenon of Class II and IV active substances by forming an ASD, and as result improving their solubility., Competing Interests: Declaration of Competing Interest None., (Copyright © 2023 Elsevier B.V. All rights reserved.)
- Published
- 2024
- Full Text
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50. Impact of food-based fortification on nutritional outcomes and acceptability in older adults: systematic literature review.
- Author
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Geny A, Petitjean M, Van Wymelbeke-Delannoy V, and Sulmont-Rossé C
- Abstract
Background: "Do it yourself" (DIY) food-based fortification involves adding fortificants into everyday foods. It is a flexible solution that allows older people with reduced appetite to meet their nutritional needs., Objectives: The aims of the systematic review are (a) to describe DIY fortified recipes, (b) to evaluate their acceptability, and (c) to evaluate whether they are effective levers to improve nutritional outcomes in older people., Methods: A systematic search of 3 databases (Web of Science, PubMed, Scopus, last searched on January 2022) was undertaken. Main eligibility criteria include older adults aged ≥60 years living at home, in an institution or in hospital. Studies carried out for a specific medical condition or targeting only micronutrient fortification were excluded. After reviewing all titles/abstracts then full-text papers, key data were extracted and synthesized narratively. The quality of included studies was assessed using Kmet et al., Results: Of 21,493 papers extracted, 44 original studies were included (3,384 participants), with 31 reporting nutritional outcomes, 3 reporting acceptability outcomes and 10 reporting both nutritional and acceptability outcomes. The review highlighted a wide variety of DIY fortified recipes, with additional energy ranging from 23 to 850 kcal/d ( M = 403; SE = 62) and/or protein ranging from 4 to 40 g/d ( M = 19; SE = 2). Compared to a standard diet, DIY fortification seems to be a valuable strategy for increasing energy and protein intake in older people. However, no strong evidence was observed on the nutritional status., Implication for Future: Further acceptability studies are crucial to ensure that DIY fortified foods are palatable and thus have a significant impact on the nutritional status. In addition, it would be useful for studies to better describe DIY recipes. This information would result in a better understanding of the factors that maximize the impact of DIY fortification on nutritional outcomes. Study registration: PROSPERO no. CRD42021244689. Systematic review registration : PROSPERO: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021244689., Competing Interests: During the past 36 months, CSGA and CHU Dijon received research grants from OGUST, SAVEURS et VIE, and INSTITUT NUTRITION. CS-R received consulting fees from BEL FOOD and author fees from Correspondances en Métabolismes Hormones Diabètes et Nutrition. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2023 Geny, Petitjean, Van Wymelbeke-Delannoy and Sulmont-Rossé.)
- Published
- 2023
- Full Text
- View/download PDF
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