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145 results on '"Dekel, Yoram"'

11. Association between early change in neutrophil‐to‐lymphocyte ratio after radical cystectomy and treatment outcomes

Author

Herzberg, Haim, primary, Lifshitz, Karin, additional, Golan, Shay, additional, Baniel, Jack, additional, Malshy, Kamil, additional, Hoffman, Azik, additional, Amiel, Gilad E., additional, Zreik, Rani, additional, Freifeld, Yuval, additional, Dekel, Yoram, additional, Lasmanovich, Rinat, additional, Lazarovich, Alon, additional, Rosenzweig, Barak, additional, Dotan, Zohar, additional, Yossepowitch, Ofer, additional, and Mano, Roy, additional

Published
2022
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14. Nutritional Status Impairment Due to Neoadjuvant Chemotherapy Predicts Post-Radical Cystectomy Complications

Author

Cohen, Sharon, primary, Gal, Jonathan, additional, Freifeld, Yuval, additional, Khoury, Sobhi, additional, Dekel, Yoram, additional, Hofman, Azik, additional, Malshi, Kamil, additional, Amiel, Gilad, additional, Sagi, Itay, additional, Leibovici, Ilan, additional, Golan, Shay, additional, Baniel, Jack, additional, Rozenzweig, Barak, additional, Dotan, Zohar, additional, and Haifler, Miki, additional

Published
2021
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19. Comparison of Partial and Radical Laparascopic Nephrectomy: Perioperative and Oncologic Outcomes for Clinical T2 Renal Cell Carcinoma

Author

Boris Friedman, Dekel Yoram, Leonid Boyarsky, Gal Rinott Mizrahi, Ilan Klein, Avi Stein, Rani Zreik, Yuval Freifeld, and Ido Orlin

Subjects
Adult, Male, medicine.medical_specialty, Urology, medicine.medical_treatment, Operative Time, 030232 urology & nephrology, urologic and male genital diseases, Nephrectomy, 03 medical and health sciences, Postoperative Complications, 0302 clinical medicine, Renal cell carcinoma, Humans, Medicine, Warm Ischemia, Carcinoma, Renal Cell, Aged, Retrospective Studies, integumentary system, business.industry, Perioperative, Length of Stay, Middle Aged, medicine.disease, Kidney Neoplasms, Surgery, Creatinine, 030220 oncology & carcinogenesis, Female, Laparoscopy, Neoplasm Recurrence, Local, business, Glomerular Filtration Rate
Abstract

Nephron-sparing surgery has emerged as the treatment of choice for small renal masses. However, its role in larger tumors remains controversial. In this study, we compare the outcomes of laparoscopic partial nephrectomy (LPN) vs those of laparoscopic radical nephrectomy (LRN) for T2 renal tumors.Thirteen patients who had LPN and 16 patients who had LRN for T2 renal tumors were retrospectively analyzed for preoperative factors (age, gender, comorbidities, hemoglobin, and creatinine levels and estimated glomerular filtration rate [eGFR]), operative and perioperative characteristics (tumor characteristics, operative time [OT], warm ischemia time [WIT], estimated blood loss [EBL], length of stay [LOS], and postoperative complications), histopathologic results, and follow-up data (eGFR and recurrences).Tumor size was comparable between groups; however, tumors in the LRN group were more endophytic, central, and closer to the collecting system. There were no cases of positive surgical margins. Median OT was 160 minutes vs 230 minutes (p = 0.0029) and EBL was 25 mL vs 100 mL ([p = 0.0027], LRN vs LPN). Median WIT in the LPN group was 27 minutes, with three zero ischemias. Minor postoperative complications (≤Clavien-Dindo III) were noted in 6.25% and 23% (LRN vs LPN). Median LOS was 4.56 and 5.77 days (LRN vs LPN), respectively. Mean postsurgery eGFR was significantly lower for the LRN group (54.5 cc/[min ·1.73 mWe show that LPN is technically feasible for T2 tumors, with acceptable intra- and perioperative outcomes. Furthermore, our results show a significant advantage in preservation of renal function for LPN without compromising oncologic results. Taken together, we believe that LPN should be considered for larger tumors based on technical feasibility rather than only tumor size.

Published
2018

23. MP03-18 DO WEATHER PARAMETERS AFFECT THE INCIDENCE OF RENAL COLIC IN A PREDOMINANTLY WARM COUNTRY? A MULTICENTER ECOLOGICAL STUDY

Author

Golomb*, Dor, primary, Goldberg, Hanan, additional, Nevo, Amihay, additional, Lavi, Arnon, additional, Zelichenko, Genady, additional, Cohen, Michael, additional, Kafka, Ilan, additional, Chertin, Boris, additional, Lezarovic, Alon, additional, Kleinman, Nir, additional, Shvero, Asaf, additional, Drori, Tomer, additional, Gan, Ramat, additional, Verchovsky, Guy, additional, Siegel, Yoram, additional, Zisman, Amnon, additional, Lezion, Rishon, additional, Boyarsky, Leonid, additional, Stein, Avi, additional, Dekel, Yoram, additional, Darawsh, Abd Elhalim, additional, Sadeh, Omer, additional, Mullerad, Michael, additional, Makayten, Matan, additional, Gofrit, Ofer, additional, Duvdevani, Mordechai, additional, Stav, Nir, additional, Halfon, Noam, additional, Porat, Amos, additional, Dagan, Beit, additional, and Lifshitz, David, additional

Published
2020
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27. PD17-05 HOW ACCURATE ARE GA68-PSMA PET/CT AND MULTIPARAMETRIC MRI IN EXCLUDING PELVIC LYMPH NODE METASTASES PRIOR TO RADICAL PROSTATECTOMY?

Author

Frumer*, Michael, primary, Baniel, Jack, additional, Bistritsky, Serge, additional, Amiel, Gilad E., additional, Hoffman, Azik, additional, Milk, Nadav, additional, Leibovitch, Ilan, additional, Sagy, Itay, additional, Mizrahi, Gal Rinott, additional, Dekel, Yoram, additional, Zisman, Amnon, additional, Haifler, Miki, additional, LeZion, Rishon, additional, and Golan, Shay, additional

Published
2019
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29. A comparison between 68Ga-labeled prostate-specific membrane antigen-PET/CT and multiparametric MRI for excluding regional metastases prior to radical prostatectomy.

Author

Frumer, Michael, Milk, Nadav, Rinott Mizrahi, Gal, Bistritzky, Sergiu, Sternberg, Itay, Leibovitch, Ilan, Dekel, Yoram, Amiel, Gilad E., Zisman, Amnon, Baniel, Jack, Haifler, Miki, Gal, Jonathan, Hoffman, Azik, Sagy, Itay, Rosenzweig, Barak, Haramaty, Rennen, and Golan, Shay

Subjects
PROSTATE-specific membrane antigen, POSITRON emission tomography computed tomography, METASTASIS, LYMPHADENECTOMY, PROSTATECTOMY, SURGICAL pathology
Abstract

Objectives: To compare the ability of 68Ga -PSMA PET/CT (PSMA PET/CT) and multiparametric MRI (mpMRI) to exclude lymph node invasion (LNI) in patients who undergo radical prostatectomy (RP). Materials and methods: A multicenter cohort of patients who underwent PSMA PET/CT and pelvic mpMRI prior to RP with pelvic lymph node dissection (PLND) was analyzed. Increased Ga68-PSMA uptake on PET/CT and enlarged (> 10 mm) or abnormal lymph nodes on mpMRI were considered positive findings. The final surgical pathology served as the standard of reference. The negative predictive value (NPV) was calculated for each modality separately, as well as the combined value. Results: Included were 89 patients with D'Amico intermediate (45%) or high-risk (55%) prostate cancer. The median number of extracted LN was 9 (IQR 6-14). LNI was found in 12 (13.5%) patients. The NPV of mpMRI, PSMA PET/CT, and the two tests combined were 87%, 89%, and 90%, in the entire cohort, 95%, 97%, and 97% in patients with intermediate-risk disease, and 80%, 82%, and 83% in patients with high-risk disease, respectively. The median diameter of LN missed by both imaging and the median intranodal tumor diameter was 5.5 (IQR 3–10) mm and 1 (IQR 1–3) mm, respectively. Conclusions: PSMA PET/CT and mpMRI demonstrated similar performance in excluding pelvic LNI with NPV of approximately 90%. The combination of both tests does not improve NPV significantly. Therefore, even in the era of advanced imaging, PLND is still recommended for accurate staging, especially in the high-risk population. [ABSTRACT FROM AUTHOR]

Published
2020
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31. An Aggressive Case of Malignant Renal Pecoma Non-Responsive to Motor Inhibition: A Case Report

Author

Leonid Boyarsky, Dekel Yoram, Klein Ilan Binyamin, Yuval Freifeld, Yoel Mecz, and Avi Stein

Subjects
0301 basic medicine, Kidney, Pathology, medicine.medical_specialty, Right flank, Everolimus, business.industry, Clinical course, Bioinformatics, Systemic metastasis, Perivascular Epithelioid Cell Tumors, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Medicine, Immunohistochemistry, business, PI3K/AKT/mTOR pathway, medicine.drug
Abstract

Perivascular epithelioid cell tumors (PEComas) are made up of cells with distinctive morphologic, immunohistochemical, ultrastructural and genetic features. They may arise in various locations and are usually benign. Malignant PEComas are rare and associated with an aggressive clinical course and metastatic spread. We present a case of a 56 years old healthy patient who presented with right flank pain and a large mass located at the medial aspect of the right kidney. The mass ruptured during laparoscopic removal. The tumor was eventually labeled as an epitheloid malignant neoplasm most suggestive of malignant PEComa. The patient demonstrated during follow up both local and systemic metastasis that are unresponsive to this point to mTOR inhibition with various agents.

Published
2016

32. Primary Primitive Neuroectodermal Tumor of the Urinary Bladder: A Case Report of a Rare Pathological Entity with a Rapidly Progressing Clinical Course

Author

Freifeld Yuval, Dekel Yoram, and Klein Ilan

Subjects
Nervous system, medicine.medical_specialty, Round cells, Pathology, Urinary bladder, business.industry, Clinical course, medicine.disease, medicine.anatomical_structure, Primitive neuroectodermal tumor, medicine, Histopathology, Sarcoma, business, Pathological
Abstract

Primary primitive neuroectodermal tumors (PNET) are a group of malignant neoplasms composed of sheets of uniform small round cells that exhibit neuroblastic differentiation outside the nervous system. They are closely related to Ewing’s sarcoma and predominantly affect children and adolescents. There are few reports of primary visceral PNET’s in the literature, most of them in the urogential organs, and even fewer reports of PNET’s of the urinary bladder. Thus, every case counts in increasing the pool of knowledge as far as the symptoms, risk factors, histopathology and treatment of this rare and aggressive entity. We present such a case.

Published
2016

36. PD11-05 THE CHEMOABLATIVE EFFECT OF VESIGEL INSTILLATION IN PATIENTS WITH NMIBC – PRELIMINARY RESULTS

Author

Friedman, Boris, primary, Dekel, Yoram, additional, Tubaro, Andrea, additional, Sidi, Ami, additional, Shalva, Benjamin, additional, Baniel, Jack, additional, Kedar, Daniel, additional, Colombo, Lorenzo, additional, Engelshtein, Dov, additional, Fridman, Edi, additional, Klein, Ifat, additional, Jeshurun, Michal, additional, Nerotski, Baruch, additional, Zolotrayov, Dima, additional, Malchi, Nadav, additional, Palou Redorta, Joan, additional, Wirth, Gregory, additional, Leibovitch, Ilan, additional, and Witjes, Fred, additional

Published
2016
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37. Successful lung transplantation for talcosis secondary to intravenous abuse of oral drug

Author

Dekel, Yoram

Subjects
International Journal of Chronic Obstructive Pulmonary Disease
Abstract

Dekel Shlomi1, David Shitrit1, Daniele Bendayan1, Gidon Sahar2, Yitshak Shechtman3, Mordechai R Kramer11Pulmonary Institute, Departments of 2Cardiothoracic Surgery and 3Pathology, Rabin Medical Center, Beilinson Campus, Petah Tiqwa, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, IsraelAbstract: Talcosis due to intravenous injection of oral drugs can cause severe pulmonary disease with progressive dyspnea even when drug use is discontinued. We describe a 54-yearold woman with severe emphysema who underwent left lung transplantation. The patient had a remote history of intravenous injection of crushed methylphenidate (Ritalin) tablets. Chest computed tomography showed severe emphysematous changes, more prominent in the lower lobes. Microscopic examination of the extracted lung demonstrated multinucleated giant cells with birefringent crystals, compatible with talcosis. At follow-up, daily symptoms were completely alleviated and lung function was good. We recommend that lung transplantation be considered as a viable option in the treatment of talcosis.Keywords: methylphenidate (Ritalin), emphysema

Published
2008

39. Successful lung transplantation for talcosis secondary to intravenous abuse of oral drug

Author

Shlomi,Dekel, Shitrit,David, Bendayan,Daniele, Sahar,Gidon, Shechtman,Yitshak, Kramer,Mordechai R, Dekel,Yoram, Shlomi,Dekel, Shitrit,David, Bendayan,Daniele, Sahar,Gidon, Shechtman,Yitshak, Kramer,Mordechai R, and Dekel,Yoram

Abstract

Dekel Shlomi1, David Shitrit1, Daniele Bendayan1, Gidon Sahar2, Yitshak Shechtman3, Mordechai R Kramer11Pulmonary Institute, Departments of 2Cardiothoracic Surgery and 3Pathology, Rabin Medical Center, Beilinson Campus, Petah Tiqwa, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, IsraelAbstract: Talcosis due to intravenous injection of oral drugs can cause severe pulmonary disease with progressive dyspnea even when drug use is discontinued. We describe a 54-yearold woman with severe emphysema who underwent left lung transplantation. The patient had a remote history of intravenous injection of crushed methylphenidate (Ritalin) tablets. Chest computed tomography showed severe emphysematous changes, more prominent in the lower lobes. Microscopic examination of the extracted lung demonstrated multinucleated giant cells with birefringent crystals, compatible with talcosis. At follow-up, daily symptoms were completely alleviated and lung function was good. We recommend that lung transplantation be considered as a viable option in the treatment of talcosis.Keywords: methylphenidate (Ritalin), emphysema

Published
2008

41. 2078 IS TOTAL ABDOMINAL EXPOSURE DURING NON-CONTRAST COMUTERIZED TOMOGRAPHY (NCCT) NECESSARY AS FOLLOW -UP(F-U) OF PATIENTS WITH URETERAL STONES?!

Author

Stein, Avi, primary, Freifeld, Yuval, additional, Avitan, ofir, additional, Molnar, Roni, additional, Mecz, Yoel, additional, Goldin, Dmitri, additional, May, Tal, additional, Klein, Ilan, additional, Sharbal, Hashul, additional, Yichie, Moad, additional, Shnap, Mati, additional, Peled, Nathan, additional, and Dekel, Yoram, additional

Published
2013
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