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Summary: A 14‐year‐old Quarter Horse gelding presented for a 2‐week history of increased respiratory rate, fever and weight loss. The referring veterinarian performed an ultrasonographic examination on the farm and considered a differential diagnosis of pleuritis and pleuropneumonia. On presentation, transtracheal wash showed suppurative septic inflammation with bacteria within macrophages. Thoracic ultrasonography showed increased hypoechoic fluid in the pleural and peritoneal cavities. Cytologic analysis of pleural and peritoneal fluids revealed lymphorrhagic effusion with atypical lymphocytes, suggestive of a lymphatic flow obstruction or lymphoma. Treatment consisted of drainage of the pleural fluid, anti‐inflammatory agents, fluid therapy and antimicrobial therapy. Continued fluid accumulation in the thoracic cavity, tachypnoea, lack of response to pain medication and progressive lethargy resulted in the horse being subjected to euthanasia. At necropsy, bicavitary effusion was confirmed and histopathological diagnosis of multicentric lymphoma was made. Horses presenting with pleural effusion should also be evaluated for peritoneal effusion, as bicavitary effusion may indicate noninflammatory conditions such as neoplasia. [ABSTRACT FROM AUTHOR]

Objectives: Pet pigs are a species of growing medical interest, and evidence-based practices for blood transfusions are needed. The objectives of this study were to quantify the prevalence of 3 blood group (Bg) phenotypes ("A" and "A weak " resulting from EAA AA and EAA AO , "0" from EAA 00 , or "-" from EAA 00 or S SS alleles) in pet pigs and compare results using a human blood-typing card (EldonCard), standard saline agglutination (SSA), and polymerase chain reaction (PCR) sequencing., Design: Cross-sectional study., Setting: University veterinary teaching hospital., Animals: Ninety-seven pet pigs from Louisiana., Interventions: Blood was sampled from randomly selected pet pigs of various breeds, anticoagulated with EDTA, and typed using each investigated test according to the manufacturers' directions or standard laboratory technique. Samples for PCR analysis were stored at -80°C until analysis. Phenotypes were screened via EldonCard. Association between Bg and sex was investigated using chi-square test, with significance at P < 0.05. Kappa (κ) statistic was used to measure the level of agreement between the 3 tests., Measurements and Main Results: Pot-bellied pigs represented the majority (84.5%) of this population, with 52 (53.6%) males and 45 (46.4%) females. Genotypic frequencies were 30%, 30%, and 40% for "EAA AA ," "EAA AO ," and "EAA 00 ," respectively. Based on EldonCard, 38 phenotypes were classified as "A," 5 as "A weak ," and 54 as "0" or "-." Results were identical for Bg, with the 3 tested techniques in 90% (45/50) of samples. Agreement between EldonCard and PCR was almost perfect (49/50 [98%], κ = 0.959; P < 0.001). Agreement between SSA and PCR, and EldonCard and SSA was substantial (46/50 [92%], κ = 0.803, P < 0.001 and 93/97 [95.9%], κ = 0.764, P < 0.001, respectively)., Conclusions: The most common blood type was "0" or "-" (55.7%), followed by "A" (39.2%) and "A weak " (5.1%). There was strong agreement between EldonCard and PCR testing. EldonCard allowed for rapid and reliable phenotype identification ("A," "A weak ," and "0" or "-") and represents a clinically applicable laboratory method for blood typing in pet pigs., (© Veterinary Emergency and Critical Care Society 2022.)

Platelet to lymphocyte ratio (PLR) is a prognostic marker in human hepatocellular carcinoma (HCC) however, its utility in canine HCC has not been explored. The aim of the study was to determine if PLR could predict survival outcomes in 42 dogs with HCC. PLR was not a significant predictive factor ( p = 0.15) but lymphopenia alone was significantly correlated with a reduced probability of survival ( p = 0.024). Further studies are needed to evaluate if peripheral lymphocyte count mirrors that of the tumor microenvironment in canine HCC., Competing Interests: Conceptualization: Johnston AN; Data curation: Suarez-Rodriguez JI; Formal analysis: Liu CC; Investigation: Suarez-Rodriguez JI; Methodology: Suarez-Rodriguez JI; Project administration: Johnston AN; Software: Liu CC; Supervision: Johnston AN; Validation: Liu CC, Dehghanpir SD Johnston AN; Visualization: Liu CC, Johnston AN; Writing - original draft: Suarez-Rodriguez JI; Writing - review & editing: Liu CC, Dehghanpir SD, Johnston AN., (© 2023 The Korean Society of Veterinary Science.)