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Endayen Deginet, Abeba Mengesha Abebe, Meskerem Abatkun Department of Pediatrics and Child Health, School of Medicine, College of Health and Medical Sciences, Saint Paul’s Hospital Millennium Medical College, Addis Ababa, EthiopiaCorrespondence: Endayen Deginet, Email endayend@gmail.comBackground: Dystonia, one of the most common movement disorders, It was mostly a result of pathology in basal ganglia; there have been increasing numbers of dystonia cases reported in patients with spinal cord pathology.Case Presentation: Here we report, a 14 year old female adolescent from Addis Ababa Ethiopia presented with dystonia of extremities within one month after she was diagnosed with transverse myelitis.Conclusion: Although any spinal cord pathology can result in spinal dystonia, demyelinating diseases are among the leading causes. There are few case reports on dystonic spasm caused by acute transverse myelitis. This case report describes an instance of spinal dystonia associated with transverse myelitis in an adolescent female.Keywords: spinal dystonia, transverse myelitis, adolescent

Endayen Deginet, Deme Abdissa, Tadele Hailu Department of Pediatrics and Child Health, School of Medicine, College of Health and Medical Sciences, Saint Paul’s Hospital Millennium Medical College, Addis Ababa, EthiopiaCorrespondence: Endayen Deginet, Email endayend@gmail.comBackground: Potocki-Lupski syndrome (PTLS) is a rare developmental disorder resulting from the partial duplication of the short arm of chromosome 17. Affected children may have hypotonia, facial dysmorphism, or neurological abnormalities.Case Presentation: We present the case of a 5-year-old female patient from Ethiopia diagnosed with Potocki-Lupski syndrome (PTLS)(17p11.2 microduplication) through multiplex ligation-dependent probe amplification (MLPA) testing. This technique identified the duplication of regions of the 17p11.2 chromosome (RAI1, DRC3, USP22, COPS3 and LLGL1). The patient exhibited neurological manifestations including speech delay and mild intellectual disability, along with craniofacial dysmorphism characterized by a triangular face, wide forehead, dental malocclusion, and micrognathia.Conclusion: A multidisciplinary team approach is imperative for managing patients with PTLS. Parental counseling and genetic advice are crucial for families with children affected by PTLS.Keywords: Potocki-Lupski syndrome, child, Ethiopia

Ahmed Abdella,1 Endayen Deginet,1 Fitsum Weldegebreal,2 Indeshaw Ketema,3 Bajrond Eshetu,4 Assefa Desalew5 1Department of Pediatrics and Child Health, School of Medicine, College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia; 2School of Medical Laboratory Sciences, College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia; 3Department of Emergency and Critical Care Nursing, School of Nursing and Midwifery, College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia; 4Department of Midwifery, School of Nursing and Midwifery, College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia; 5Department of Pediatrics and Child Health Nursing, School of Nursing and Midwifery, College of Health and Medical Sciences, Haramaya University, Harar, EthiopiaCorrespondence: Assefa Desalew, Email assefad100@gmail.comBackground: Tuberculous meningitis is a serious public health problem, particularly in low-income countries. It is associated with high rates of mortality and morbidity. The outcome of tuberculous meningitis in children is not well documented in Ethiopia, particularly in eastern Ethiopia. This study aimed to determine the treatment outcomes of tuberculous meningitis at discharge and its associated factors in eastern Ethiopia.Methods: An institutional-based retrospective cross-sectional study was conducted on 121 children who were admitted and treated for tuberculous meningitis between January 2017 and December 2021. Data were collected using a pretested checklist, coded and entered into EpiData version 3.1, and analyzed using Statistical Package for the Social Sciences (SPSS) version 25. Factors associated with treatment outcomes were identified using multivariable logistic regression analyses. The association was described using the adjusted odds ratio (AOR) at a 95% confidence interval (CI). Finally, statistical significance was set at a p-value < 0.05.Results: Of the 121 medical records of c