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This article, titled "Circulating angiogenic factors levels in women with hypertensive disorders of pregnancy according to the baseline hemodynamic findings," explores the relationship between hemodynamic phenotype and the predictive value of sFLT‐1/PlGF ratio for adverse outcomes in women with hypertensive disorders of pregnancy (HDP). The study included a cohort of women with new-onset HDP and assessed their hemodynamic parameters using USCOM-1A. The results showed that the sFLT1/PlGF ratio was significantly higher in women with a hypodynamic profile, and there was a significant association between the ratio and adverse maternal and neonatal outcomes in this group. Overall, the findings suggest that the sFLT1/PlGF ratio is associated with adverse outcomes only in women with a hypodynamic profile. [Extracted from the article]

This article, titled "EP19.15: Intrapartum assessment of head-perineum distance: a comparative study of measurements obtained with and without compression of perineal soft tissues," presents the findings of a study that aimed to evaluate and compare measurements of the head-perineum distance (HPD) obtained with and without compression of the perineal soft tissues. The study involved a series of singleton pregnancies and used transperineal sonography to evaluate the HPD. The results showed a good correlation and reproducibility between the HPD measured with and without compression, and it was also found that the body mass index at delivery may impact the difference in measurements. [Extracted from the article]

This article, published in the journal Ultrasound in Obstetrics & Gynecology, explores the correlation between angiogenetic biomarkers, urinary protein values, and the presence of maternal ascites in women with new-onset Hypertensive Disorders of Pregnancy (HDP). The study included 80 patients with new-onset HDP and found a linear correlation between the SFLT-1/PlGF ratio and 24-hour urinary protein values. Additionally, higher values of the SFLT-1/PlGF ratio were associated with higher levels of urinary protein and a higher incidence of maternal ascites. The findings suggest a potential link between these biomarkers and the severity of HDP. [Extracted from the article]

This article, titled "EP01.05: Prenatal estimation of fetal femur bone mineral density using an artificial intelligence-based algorithm and relationship with birthweight: a prospective validation study," discusses a study conducted in Italy to evaluate the relationship between the bone mineral density (BMD) of the fetal femur estimated by an artificial intelligence (AI)-based algorithm and birthweight. The study included a cohort of singleton pregnancies undergoing routine prenatal care assessment, and a standard image of the fetal femur was acquired and processed using the AI algorithm to estimate BMD. The results showed a negative correlation between the algorithm output and birthweight, and the algorithm was also associated with the postnatal diagnosis of small-for-gestational age (SGA) after adjusting for potential confounders. Overall, the study suggests that the AI-based algorithm has potential in predicting birthweight and identifying SGA. [Extracted from the article]

Cancer is the leading cause of death in women of reproductive age. During the last decades and especially in developed countries, the incidence of cancer is increasing dramatically, with an incidence of 1 in 1,000 pregnancies. This is mostly related to delay of pregnancy into the late reproductive years. The aim of this study was to investigate the outcome of pregnancy in women with diagnosis of cancer; in particular, neonatal morbidity and mortality, after in utero exposure to chemotherapy, were evaluated. A total of 59 singletons and one twin pregnancy complicated by cancer were followed at our tertiary centre over the last 15 years. A different treatment, based on surgery and/or chemotherapy in pregnancy or delayed to the postpartum period, was employed. There were 59 live births (97%), one foetal loss and one stillbirth at 28 weeks. The congenital malformation rate was 5% ( n = 3). The rate of preterm birth was 83%. The mean birthweight and mean birthweight percentile were 2,098 g (740-3930) and 46 (7-93), respectively; 32% of neonates were small for gestational age ( SGA). Dividing the population into treated or untreated with chemotherapy, the rate of SGA was not statistically significant different between the two groups. Our results showed that chemotherapy administered during the second trimester or later did not influence intrauterine foetal growth, but the high prevalence of SGA neonates in the two groups, exposed or not exposed to chemotherapy, suggests an influence of maternal cancer per se on foetal growth. [ABSTRACT FROM AUTHOR]