282 results on '"Deenick, Elissa K."'
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2. Tracking the clonal dynamics of SARS-CoV-2-specific T cells in children and adults with mild/asymptomatic COVID-19
3. Inherited human RelB deficiency impairs innate and adaptive immunity to infection.
4. Genomic Spectrum and Phenotypic Heterogeneity of Human IL-21 Receptor Deficiency
5. Increased core body temperature exacerbates defective protein prenylation in mouse models of mevalonate kinase deficiency
6. Everolimus-Induced Remission of Classic Kaposi’s Sarcoma Secondary to Cryptic Splicing Mediated CTLA4 Haploinsufficiency
7. Activating mutations in PIK3CD disrupt the differentiation and function of human and murine CD4+ T cells
8. Immune Dysregulation and Disease Pathogenesis due to Activating Mutations in PIK3CD—the Goldilocks’ Effect
9. Inborn errors of human B cell development, differentiation, and function
10. Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency
11. Reversible Suppression of Lymphoproliferation and Thrombocytopenia with Rapamycin in a Patient with Common Variable Immunodeficiency
12. Monitoring AKT activity and targeting in live tissue and disease contexts using a real-time Akt-FRET biosensor mouse
13. Human PIK3R1 mutations disrupt lymphocyte differentiation to cause activated PI3Kδ syndrome 2
14. CARD11 gain-of-function mutation drives cell-autonomous accumulation of PD-1+ ICOShigh activated T cells, T-follicular, T-regulatory and T-follicular regulatory cells
15. Monogenic mutations differentially affect the quantity and quality of T follicular helper cells in patients with human primary immunodeficiencies
16. Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations
17. STAT5B restrains human B-cell differentiation to maintain humoral immune homeostasis
18. Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4
19. IL-21 signalling via STAT3 primes human naïve B cells to respond to IL-2 to enhance their differentiation into plasmablasts
20. Monitoring T Cell Proliferation
21. For whom the B cells toll
22. CARD11 gain-of-function mutation drives cell- autonomous accumulation of PD-1+ ICOShigh activated T cells, T-follicular, T-regulatory and T-follicular regulatory cells.
23. Functional STAT3 deficiency compromises the generation of human T follicular helper cells
24. T cell extrinsic mechanics explaining the T cell hyperactivation seen in Activated PI3K δ Syndrome
25. Increased core body temperature exacerbates defective protein prenylation in mouse avatars of mevalonate kinase deficiency
26. Clonal dynamics of SARS-CoV-2-specific T cells in children and adults with COVID-19
27. The role of dysregulated PI3Kdelta signaling in human autoimmunity*
28. IMMUNODEFICIENCIES: Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations
29. T Follicular Helper Cells Have Distinct Modes of Migration and Molecular Signatures in Naive and Memory Immune Responses
30. Phosphatidylinositol 3-kinase signaling and immune regulation: insights into disease pathogenesis and clinical implications
31. IMMUNODEFICIENCY: Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4
32. Human T follicular helper (Tfh) cells and disease
33. The sound of silence: modulating anergy in T lymphocytes
34. TCR affinity and negative regulation limit autoimmunity
35. T cell–B cell interactions in primary immunodeficiencies
36. B cell–intrinsic requirement for STK4 in humoral immunity in mice and human subjects
37. The regulation and role of T follicular helper cells in immunity
38. The role of SAP and SLAM family molecules in the humoral immune response
39. B cells: we need them now more than ever
40. Molecular and cellular mechanisms underlying defective antibody responses
41. A divergent transcriptional landscape underpins the development and functional branching of MAIT cells
42. NK Cells Regulate CD8+ T Cell Mediated Autoimmunity
43. Follicular Helper T Cell Differentiation Requires Continuous Antigen Presentation that Is Independent of Unique B Cell Signaling
44. Human Th9 cells: inflammatory cytokines modulate IL-9 production through the induction of IL-21
45. Activated PI3Kδ breaches multiple B cell tolerance checkpoints and causes autoantibody production
46. Early commitment of naïve human CD4+ T cells to the T follicular helper (TFH) cell lineage is induced by IL-12
47. IMMUNOLOGY: Helpful T cells are sticky
48. Activating mutations in PIK3CD and murine CD4(+) T cells
49. Autoimmunity: IL-21: a new player in Th17-cell differentiation
50. Signal transducer and activator of transcription 3 (STAT3) mutations underlying autosomal dominant hyper-IgE syndrome impair human CD8+ T-cell memory formation and function
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