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3. An intra-covid-19 assessment of hand hygiene facility, policy and staff compliance in two hospitals in Sierra Leone: Is there a difference between regional and capital city hospitals?

Author

Lakoh, Sulaiman, Firima, Emmanuel, Williams, Christine Ellen Elleanor, Conteh, Sarah K, Jalloh, Mohamed Boie, Sheku, Mohamed Gbeshay, Adekanmbi, Olukemi, Sevalie, Stephen, Kamara, Sylvia Adama, Kamara, Mohamed Akmed Salim, Barrie, Umu, Kamara, Gladys Nanilla, Yi, Le, Guo, Xuejun, Haffner, Chukwuemeka, Kamara, Matilda N, Jiba, Darlinda F, Namanaga, Enanga Sonia, Maruta, Anna, Kallon, Christiana, Kanu, Joseph Sam, Deen, Gibrilla F, Samai, Mohamed, Okeibunor, Joseph Chukwudi, and Russell, James BW

Published
2021

6. High incidence of catheter-associated urinary tract infections and related antibiotic resistance in two hospitals of different geographic regions of Sierra Leone: a prospective cohort study

Author

Lakoh, Sulaiman, Yi, Le, Russell, James B.W., Zhang, Juling, Sevalie, Stephen, Zhao, Yongkun, Kanu, Joseph Sam, Liu, Peng, Conteh, Sarah K., Williams, Christine Ellen Elleanor, Barrie, Umu, Adekanmbi, Olukemi, Jiba, Darlinda F., Kamara, Matilda N., Sesay, Daniel, Deen, Gibrilla F., Okeibunor, Joseph Chukwudi, Yendewa, George A., Guo, Xuejun, and Firima, Emmanuel

Published
2023
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9. Antibiotic use and consumption in Freetown, Sierra Leone: A baseline report of prescription stewardship in outpatient clinics of three tertiary hospitals

Author

Lakoh, Sulaiman, John-Cole, Valerie, Luke, Ronita D.C., Bell, Nellie, Russell, James B.W., Mustapha, Ayeshatu, Barrie, Umu, Abiri, Onome T., Coker, Joshua M., Kamara, Matilda N., Coker, Freddie J., Adekanmbi, Olukemi, Kamara, Ibrahim Franklyn, Fofanah, Bobson Derrick, Jiba, Darlinda F., Adeniji, Adetunji O., Kenneh, Sartie, Deen, Gibrilla F., Moon, Troy D., Yendewa, George A., and Firima, Emmanuel

Published
2023
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10. A scoping review of stroke registers in Sub-Saharan Africa.

Author

Youkee, Daniel, Baldeh, Mamadu, Rudd, Anthony, Soley-Bori, Marina, Wolfe, Charles DA, Deen, Gibrilla F, and Marshall, Iain J

Subjects
STROKE, GLASGOW Coma Scale, QUALITY-adjusted life years, SUMMIT meetings, BARTHEL Index
Abstract

Background: Stroke registers are recommended as a key priority by the Lancet Neurology World Stroke Organization Commission for Stroke, 2023, and the African Stroke Leaders' Summit, 2022. Aims: This scoping review aims to map where stroke registers have been implemented in Sub-Saharan Africa (SSA). The article then compares and critiques the methods and definitions used and summarizes key results from the registers. The scoping review searched EMBASE, MEDLINE, and CABI Global Health databases and included all studies with a prospective longitudinal design in SSA, where adult acute stroke was the primary condition studied. Articles were screened against inclusion and exclusion criteria independently by two authors. Summary: We identified 42 unique stroke registers from 48 individual studies. The registers were located in 19 countries, with 19 from East Africa, 15 West Africa, 6 Central Africa, and 2 from Southern Africa. Cumulatively, the registers recruited 12,345 participants with stroke, the median number of participants was 183 (interquartile range (IQR): 121–312), and the range was 50–1018. Only one study was a population-based register, and 41 were hospital-based registers. Of the hospital-based registers, 29 were single site, 10 were conducted at two sites, and 2 at three sites. Twenty-three (54.7%) of the registers were located in the capital city of their respective country, and only one of the hospital-based registers was in a self-described rural area. Length of recruitment ranged from 4 months to 6 years; the median length of recruitment was 12 months. Methodology and definitions were heterogenous between the registers. Only seven (19.4%) registers referenced the WHO STEPwise approach to implementing stroke registers. Twenty-seven (64.3%) registers used the WHO definition of stroke. The mean neuroimaging rate was 84%, and ranged from 0% to 100%. Stroke severity was measured using the National Institute of Health Stroke Scale (NIHSS) in 22 (52.4%) registers, four registers used the Glasgow Coma Scale (GCS), two registers used the miniNIHSS, one used the Scandinavian Stroke Scale, one modified Rankin Scale (mRS), and 11 registers did not report a stroke severity measure. Seventeen (40.5%) registers used the mRS to measure function, six registers used Barthel Index alone, and three registers used both mRS and Barthel Index. Only two registers included a quality-of-life measure, the EQ-5D. Eight registers included a quality-of-care measure, and 26 (61.9%) registers recorded socioeconomic status or a socioeconomic status proxy, most frequently educational attainment. Conclusions: This scoping review found high heterogeneity of methods and definitions used by stroke registers, with low uptake of the WHO stepwise method of stroke surveillance. A drive to standardize methodology would improve the comparability of stroke data in SSA. The shared use of educational attainment by registers in our review may enable future meta-analyses of inequities in stroke in SSA. Incorporating health-related quality-of-life measures, such as EQ-5D, into stroke registers should be encouraged, bringing a patient perspective, and allow the estimation of quality-adjusted life years lost to stroke. Agreement on a standardized register methodology or further promotion and uptake of the WHO stepwise method is essential to produce comparable data to improve stroke prevention and care. [ABSTRACT FROM AUTHOR]

Published
2025
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11. Incidence and risk factors of surgical site infections and related antibiotic resistance in Freetown, Sierra Leone: a prospective cohort study

Author

Lakoh, Sulaiman, Yi, Le, Sevalie, Stephen, Guo, Xuejun, Adekanmbi, Olukemi, Smalle, Isaac O., Williams, Nathaniel, Barrie, Umu, Koroma, Celesis, Zhao, Yongkun, Kamara, Matilda N., Cummings-John, Constance, Jiba, Darlinda F., Namanaga, Enanga Sonia, Deen, Betsy, Zhang, Juling, Maruta, Anna, Kallon, Christiana, Liu, Peng, Wurie, Haja Ramatulai, Kanu, Joseph Sam, Deen, Gibrilla F., Samai, Mohamed, Sahr, Foday, and Firima, Emmanuel

Published
2022
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12. Prevalence of hepatitis B surface antigen and serological markers of other endemic infections in HIV-infected children, adolescents and pregnant women in Sierra Leone: A cross-sectional study

Author

Yendewa, George A., Lakoh, Sulaiman, Yendewa, Sahr A., Bangura, Khadijah, Lawrence, Hannah, Patiño, Lucia, Jiba, Darlinda F., Vandy, Alren O., Murray, Mariama J.S., Massaquoi, Samuel P., Deen, Gibrilla F., Sahr, Foday, Hoffmann, Christopher J., Jacobson, Jeffrey M., Poveda, Eva, Aguilera, Antonio, and Salata, Robert A.

Published
2021
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13. Quality of life and quality-adjusted life years after stroke in Sierra Leone.

Author

Youkee, Daniel, Deen, Gibrilla F, Sackley, Catherine, Lisk, Durodami R, Marshall, Iain, and Soley-Bori, Marina

Subjects
*QUALITY-adjusted life years, *STROKE, *STROKE patients, *QUALITY of life, *SUBARACHNOID hemorrhage
Abstract

Background: Stroke is a leading cause of mortality and negatively affects health-related quality of life (HRQoL). HRQoL after stroke is understudied in Africa and there are no reports of quality-adjusted life years after stroke (QALYs) in African countries. We determined the impact of stroke on HRQoL after stroke in Sierra Leone. We calculated QALYs at 1 year post-stroke and determined sociodemographic and clinical variables associated with HRQoL and QALYs in this population. Methods: A prospective stroke register was established at the two-principal adult tertiary government hospitals in Freetown, Sierra Leone. Participants were followed up at 7, 90 days, and 1 year post-stroke to capture all-cause mortality and EQ-5D-3L data. QALYs were calculated at the patient level using EQ-5D-3L utility values and survival data from the register, following the area under the curve method. Utilities were based on the UK and Zimbabwe (as a sensitivity analysis) EQ-5D value sets, as there is no Sierra Leonean or West African value set. Explanatory models were developed based on previous literature to assess variables associated with HRQoL and QALYs at 1 year after stroke. To address missing values, Multiple Imputation by Chained Equations (MICE), with linear and logistic regression models for continuous and binary variables, respectively, were used. Results: EQ-5D-3L data were available for 373/460 (81.1%), 360/367 (98.1%), and 299/308 (97.1%) participants at 7, 90 days, and 1 year after stroke. For stroke survivors, median EQ-5D-3L utility increased from 0.20 (95% CI: −0.16 to 0.59) at 7 days post-stroke to 0.76 (0.47 to 1.0) at 90 days and remained stable at 1 year 0.76 (0.49 to 1.0). Mean QALYs at 1 year after stroke were 0.28 (SD: 0.35) and closely associated with stroke severity. Older age, lower educational attainment, patients with subarachnoid hemorrhage and undetermined stroke types all had lower QALYs and lower HRQoL, while being the primary breadwinner was associated with higher HRQoL. Sensitivity analysis with the Zimbabwe value set did not significantly change regression results but did influence the absolute values with Zimbabwe utility values being higher, with fewer utility values less than 0. Conclusion: We generated QALYs after stroke for the first time in an African country. QALYs were significantly lower than studies from outside Africa, partially explained by the high mortality rate in our cohort. Further research is needed to develop appropriate value sets for West African countries and to examine QALYs lost due to stroke over longer time periods. Data availability: The Stroke in Sierra Leone anonymized dataset is available on request to researchers, see data access section. [ABSTRACT FROM AUTHOR]

Published
2024
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17. Health Conditions in an Adult Population in Sierra Leone : Data Reported From the Sierra Leone Trial to Introduce a Vaccine Against Ebola (STRIVE)

Author

Fombah, Augustin E., Goldstein, Susan T., Jarrett, Olamide D., Jalloh, Mohamed I., El-Khorazaty, Jill, Lisk, Durodami Radcliffe, Legardy-Williams, Jennifer, Pratt, Dudley A., George, Peter M., Russell, James B. W., Schrag, Stephanie J., Dawson, Peter, Deen, Gibrilla F., Carr, Wendy, Lindblad, Robert, James, Faustine, Bah, Mohamed M., Yillia, John F., Sandy, Jibao D., Turay, Patrick E., Conteh, Muhammad-Abbas, Slutsker, Laurence, Mahon, Barbara E., Samai, Mohamed, and Seward, Jane F.

Published
2018

18. Monitoring Serious Adverse Events in the Sierra Leone Trial to Introduce a Vaccine Against Ebola

Author

Jarrett, Olamide D., Seward, Jane F., Fombah, Augustin E., Lindblad, Robert, Jalloh, Mohamed I., El-Khorazaty, Jill, Dawson, Peter, Burton, Deron, Zucker, Jane, Carr, Wendy, Bah, Mohamed M., Deen, Gibrilla F., George, Peter M, James, Faustine, Lisk, Durodami R., Pratt, Dudley, Russell, James B. W., Sandy, Jibao D., Turay, Patrick, Hamel, Mary J., Schrag, Stephanie J., Walker, Robert E., Samai, Mohamed, and Goldstein, Susan T.

Published
2018

19. Community-based models of care for management of type 2 diabetes mellitus among non-pregnant adults in sub-Saharan Africa: A scoping review

Author

Firima, Emmanuel, primary, Gonzalez, Lucia, additional, Ursprung, Fabiola, additional, Robinson, Elena, additional, Huber, Jacqueline, additional, Belus, Jennifer M., additional, Raeber, Fabian, additional, Gupta, Ravi, additional, Deen, Gibrilla F., additional, Amstutz, Alain, additional, Leigh, Bailah, additional, Weisser, Maja, additional, and Labhardt, Niklaus Daniel, additional

Published
2023
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21. Case Series of Severe Neurologic Sequelae of Ebola Virus Disease during Epidemic, Sierra Leone

Author

Howlett, Patrick J., Walder, Anna R., Lisk, Durodami R., Fitzgerald, Felicity, Sevalie, Stephen, Lado, Marta, Njai, Abdul, Brown, Colin S., Sahr, Foday, Sesay, Foday, Read, Jonathan M., Steptoe, Paul J., Beare, Nicholas A.V., Dwivedi, Reena, Solbrig, Marylou, Deen, Gibrilla F., Solomon, Tom, Semple, Malcolm G., and Scott, Janet T.

Subjects
Complications and side effects, Research, Risk factors, Ebola hemorrhagic fever -- Complications and side effects -- Research, Mental disorders -- Risk factors -- Research, Nervous system diseases -- Risk factors -- Research
Abstract

The 2014-2016 West Africa Ebola virus disease (EVD) epidemic resulted in an estimated 3,956 deaths and 10,168 survivors in Sierra Leone (1). The use of high quality specialty services by [...]

Published
2018
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22. Impact of COVID-19 on the Utilization of HIV Testing and Linkage Services in Sierra Leone: Experience from Three Public Health Facilities in Freetown

Author

Lakoh, Sulaiman, primary, Bangura, Moses M., additional, Adekanmbi, Olukemi, additional, Barrie, Umu, additional, Jiba, Darlinda F., additional, Kamara, Matilda N., additional, Sesay, Daniel, additional, Jalloh, Abdulai Tejan, additional, Deen, Gibrilla F., additional, Russell, James B. W., additional, Egesimba, Ginika, additional, Yendewa, George A., additional, and Firima, Emmanuel, additional

Published
2023
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23. Cohort Profile: The Stroke in Sierra Leone (SISLE) Register

Author

Youkee, Daniel, primary, Marshall, Iain J, additional, Fox-Rushby, Julia, additional, Lisk, Durodami R, additional, O’Hara, Jessica, additional, Wang, Yanzhong, additional, Rudd, Anthony, additional, Wolfe, Charles D A, additional, Deen, Gibrilla F, additional, and Sackley, Catherine, additional

Published
2023
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24. Prevalence and predictors of Aspergillus seropositivity and chronic pulmonary aspergillosis in an urban tertiary hospital in Sierra Leone: A cross-sectional study

Author

Lakoh, Sulaiman, primary, Kamara, Joseph B., additional, Orefuwa, Emma, additional, Sesay, Daniel, additional, Jiba, Darlinda F., additional, Adekanmbi, Olukemi, additional, Deen, Gibrilla F., additional, Russell, James B. W., additional, Bah, Abubakarr Bailor, additional, Kargbo, Maxwell Joseph, additional, Firima, Emmanuel, additional, Yendewa, George A., additional, and Denning, David W., additional

Published
2023
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27. Prevalence of Chronic Hepatitis B Virus Infection in Sierra Leone, 1997–2022: A Systematic Review and Meta-Analysis

Author

Yendewa, George A., primary, Wang, Gi-Ming, additional, James, Peter B., additional, Massaquoi, Samuel P. E., additional, Yendewa, Sahr A., additional, Ghazawi, Manal, additional, Babawo, Lawrence S., additional, Ocama, Ponsiano, additional, Russell, James B. W., additional, Deen, Gibrilla F., additional, Sahr, Foday, additional, Kabba, Mustapha, additional, Tatsuoka, Curtis, additional, Lakoh, Sulaiman, additional, and Salata, Robert A., additional

Published
2023
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28. sj-docx-1-wso-10.1177_17474930231164892 – Supplemental material for Stroke in Sierra Leone: Case fatality rate and functional outcome after stroke in Freetown

Author

Youkee, Daniel, Deen, Gibrilla F, Baldeh, Mamadu, Conteh, Zainab F, Fox-Rushby, Julia, Gbessay, Musa, Johnson, Jotham, Langhorne, Peter, Leather, Andrew JM, Lisk, Durodami R, Marshall, Iain J, O’Hara, Jessica, Pessima, Sahr, Rudd, Anthony, Soley-Bori, Marina, Thompson, Melvina, Wafa, Hatem, Wang, Yanzhong, Watkins, Caroline L, Williams, Christine E, Wolfe, Charles DA, and Sackley, Catherine M

Subjects
FOS: Clinical medicine, Cardiology, Medicine, 110904 Neurology and Neuromuscular Diseases
Abstract

Supplemental material, sj-docx-1-wso-10.1177_17474930231164892 for Stroke in Sierra Leone: Case fatality rate and functional outcome after stroke in Freetown by Daniel Youkee, Gibrilla F Deen, Mamadu Baldeh, Zainab F Conteh, Julia Fox-Rushby, Musa Gbessay, Jotham Johnson, Peter Langhorne, Andrew JM Leather, Durodami R Lisk, Iain J Marshall, Jessica O’Hara, Sahr Pessima, Anthony Rudd, Marina Soley-Bori, Melvina Thompson, Hatem Wafa, Yanzhong Wang, Caroline L Watkins, Christine E Williams, Charles DA Wolfe and Catherine M Sackley in International Journal of Stroke

Published
2023
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29. Stroke in Sierra Leone: Case fatality rate and functional outcome after stroke in Freetown

Author

Youkee, Daniel, primary, Deen, Gibrilla F, additional, Baldeh, Mamadu, additional, Conteh, Zainab F, additional, Fox-Rushby, Julia, additional, Gbessay, Musa, additional, Johnson, Jotham, additional, Langhorne, Peter, additional, Leather, Andrew JM, additional, Lisk, Durodami R, additional, Marshall, Iain J, additional, O’Hara, Jessica, additional, Pessima, Sahr, additional, Rudd, Anthony, additional, Soley-Bori, Marina, additional, Thompson, Melvina, additional, Wafa, Hatem, additional, Wang, Yanzhong, additional, Watkins, Caroline L, additional, Williams, Christine E, additional, Wolfe, Charles DA, additional, and Sackley, Catherine M, additional

Published
2023
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30. High incidence of catheter-associated urinary tract infections and related antibiotic resistance in two hospitals of different geographic regions of Sierra Leone: a prospective cohort study

Author

LAKOH, Sulaiman, primary, Yi, Le, additional, RUSSELL, James B.W., additional, ZHANG, Juling, additional, SEVALIE, Stephen, additional, ZHAO, Yongkun, additional, KANU, Josep Sam, additional, LIU, Peng, additional, CONTEH, Sarah K., additional, WILLIAMS, Christine Ellen Elleanor, additional, BARRIE, Umu, additional, ADEKANMBI, Olukemi, additional, JIBA, Darlinda F., additional, KAMARA, Matilda N., additional, SESAY, Daniel, additional, DEEN, Gibrilla F., additional, OKEIBUNOR, Joseph Chukwudi, additional, YENDEWA, George A., additional, GUO, Xuejun, additional, and FIRIMA, Emmanuel, additional

Published
2023
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31. Childhood Hepatitis B Immunization Coverage and Barriers in Sierra Leone, Liberia, and Guinea: Analysis of National Surveys (2018-2020)

Author

Yendewa, George A, primary, James, Peter Bai, additional, Mohareb, Amir M., additional, Barrie, Umaru, additional, Massaquoi, Samuel P.E., additional, Yendewa, Sahr A, additional, Ghazzawi, Manal, additional, Bockarie, Tahir, additional, Cummings, Peterlyn E, additional, Diallo, Ibrahima S, additional, Johnson, Ambulai, additional, Vohnm, Benjamin, additional, Babawo, Lawrence S, additional, Deen, Gibrilla F., additional, Kabba, Mustapha, additional, Sahr, Foday, additional, Lakoh, Sulaiman, additional, and Salata, Robert A, additional

Published
2023
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32. Establishing an Antimicrobial Stewardship Program in Sierra Leone: A Report of the Experience of a Low-Income Country in West Africa

Author

Lakoh, Sulaiman, primary, Bawoh, Mohamed, additional, Lewis, Hannah, additional, Jalloh, Ishmael, additional, Thomas, Catherine, additional, Barlatt, Shuwary, additional, Jalloh, Abdulai, additional, Deen, Gibrilla F., additional, Russell, James B. W., additional, Kabba, Mustapha S., additional, Batema, Moses N. P., additional, Borgstein, Cecily, additional, Sesay, Noah, additional, Sesay, Daniel, additional, Nagi, Navjeet K., additional, Firima, Emmanuel, additional, and Thomas, Suzanne, additional

Published
2023
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33. Assessment of Knowledge, Stigmatizing Attitudes and Health-Seeking Behaviors Regarding Hepatitis B Virus Infection in a Pharmacy and Community Setting in Sierra Leone: A Cross-Sectional Study

Author

Ghazzawi, Manal, primary, Yendewa, Sahr A., additional, James, Peter B., additional, Massaquoi, Samuel P., additional, Babawo, Lawrence S., additional, Sahr, Foday, additional, Deen, Gibrilla F., additional, Kabba, Mustapha, additional, Ocama, Ponsiano, additional, Lakoh, Sulaiman, additional, Salata, Robert A., additional, and Yendewa, George A., additional

Published
2023
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34. Determinants of incomplete childhood hepatitis B vaccination in Sierra Leone, Liberia, and Guinea: Analysis of national surveys (2018–2020)

Author

Yendewa, George A., primary, James, Peter B., additional, Mohareb, Amir, additional, Barrie, Umaru, additional, Massaquoi, Samuel P. E., additional, Yendewa, Sahr A., additional, Ghazzawi, Manal, additional, Bockarie, Tahir, additional, Cummings, Peterlyn E., additional, Diallo, Ibrahima S., additional, Johnson, Ambulai, additional, Vohnm, Benjamin, additional, Babawo, Lawrence S., additional, Deen, Gibrilla F., additional, Kabba, Mustapha, additional, Sahr, Foday, additional, Lakoh, Sulaiman, additional, and Salata, Robert A., additional

Published
2023
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35. Randomized Trial of Vaccines for Zaire Ebola Virus Disease

Author

Kieh, Mark, Richert, Laura, Beavogui, Abdoul H., Grund, Birgit, Leigh, Bailah, D’ortenzio, Eric, Doumbia, Seydou, Lhomme, Edouard, Sow, Samba, Vatrinet, Renaud, Roy, Céline, Kennedy, Stephen B., Faye, Sylvain, Lees, Shelley, Millimouno, Niouma P., Camara, Alseny M., Samai, Mohamed, Deen, Gibrilla F., Doumbia, Moussa, Espérou, Hélène, Pierson, Jerome, Watson-Jones, Deborah, Diallo, Alpha, Wentworth, Deborah, Mclean, Chelsea, Simon, Jakub, Wiedemann, Aurélie, Dighero-Kemp, Bonnie, Hensley, Lisa, Lane, Clifford, Levy, Yves, Piot, Peter, Greenwood, Brian, Chêne, Geneviève, Neaton, James, Yazdanpanah, Yazdan, CHU de Bordeaux Pellegrin [Bordeaux], Statistics In System biology and Translational Medicine (SISTM), Inria Bordeaux - Sud-Ouest, Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria)- Bordeaux population health (BPH), and Université de Bordeaux (UB)-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Bordeaux (UB)-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM)

Subjects
[SDV]Life Sciences [q-bio], General Medicine
Abstract

Questions remain concerning the rapidity of immune responses and the durability and safety of vaccines used to prevent Zaire Ebola virus disease.We conducted two randomized, placebo-controlled trials - one involving adults and one involving children - to evaluate the safety and immune responses of three vaccine regimens against Zaire Ebola virus disease: Ad26.ZEBOV followed by MVA-BN-Filo 56 days later (the Ad26-MVA group), rVSVΔG-ZEBOV-GP followed by placebo 56 days later (the rVSV group), and rVSVΔG-ZEBOV-GP followed by rVSVΔG-ZEBOV-GP 56 days later (the rVSV-booster group). The primary end point was antibody response at 12 months, defined as having both a 12-month antibody concentration of at least 200 enzyme-linked immunosorbent assay units (EU) per milliliter and an increase from baseline in the antibody concentration by at least a factor of 4.A total of 1400 adults and 1401 children underwent randomization. Among both adults and children, the incidence of injection-site reactions and symptoms (e.g., feverishness and headache) was higher in the week after receipt of the primary and second or booster vaccinations than after receipt of placebo but not at later time points. These events were largely low-grade. At month 12, a total of 41% of adults (titer, 401 EU per milliliter) and 78% of children (titer, 828 EU per milliliter) had a response in the Ad26-MVA group; 76% (titer, 992 EU per milliliter) and 87% (titer, 1415 EU per milliliter), respectively, had a response in the rVSV group; 81% (titer, 1037 EU per milliliter) and 93% (titer, 1745 EU per milliliter), respectively, had a response in the rVSV-booster group; and 3% (titer, 93 EU per milliliter) and 4% (titer, 67 EU per milliliter), respectively, had a response in the placebo group (P0.001 for all comparisons of vaccine with placebo). In both adults and children, antibody responses with vaccine differed from those with placebo beginning on day 14.No safety concerns were identified in this trial. With all three vaccine regimens, immune responses were seen from day 14 through month 12. (Funded by the National Institutes of Health and others; PREVAC ClinicalTrials.gov number, NCT02876328; EudraCT numbers, 2017-001798-18 and 2017-001798-18/3rd; and Pan African Clinical Trials Registry number, PACTR201712002760250.).

Published
2022
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36. Prevalence and Burden of Chronic Hepatitis B Virus Infection in Sierra Leone, 1997-2022: Evidence from a 25-Year Systematic Review and Meta-Analysis

Author

Yendewa, George A., primary, Wang, Gi-Ming, additional, James, Peter B., additional, Massaquoi, Samuel P.E., additional, Yendewa, Sahr A., additional, Ghazawi, Manal, additional, Babawo, Lawrence S., additional, Ocama, Ponsiano, additional, Russell, James B.W., additional, Deen, Gibrilla F., additional, Sahr, Foday, additional, Kabba, Mustapha, additional, Tatsuoka, Curtis, additional, Lakoh, Sulaiman, additional, and Salata, Robert A., additional

Published
2022
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37. Community-based models of care for management of type 2 diabetes mellitus among non-pregnant adults in sub-Saharan Africa: a scoping review

Author

Firima, Emmanuel, primary, Gonzalez, Lucia, additional, Ursprung, Fabiola, additional, Robinson, Elena, additional, Huber, Jacqueline, additional, Belus, Jennifer M., additional, Raeber, Fabian, additional, Gupta, Ravi, additional, Deen, Gibrilla F., additional, Amstutz, Alain, additional, Leigh, Bailah, additional, Weisser, Maja, additional, and Labhardt, Niklaus Daniel, additional

Published
2022
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38. Assessment of Knowledge, Stigmatizing Attitudes and Health-Seeking Behaviors Regarding Hepatitis B Virus Infection in a Community and Pharmacy Setting in Sierra Leone: A Cross-Sectional Study

Author

Ghazzawi, Manal, primary, Yendewa, Sahr, additional, James, Peter B., additional, Massaquoi, Samuel P., additional, Babawo, Lawrence S., additional, Sahr, Foday, additional, Deen, Gibrilla F., additional, Kabba, Mustapha, additional, Ocama, Ponsiano, additional, Lakoh, Sulaiman, additional, Salata, Robert A., additional, and Yendewa, George A., additional

Published
2022
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39. Ebola RNA Persistence in Semen of Ebola Virus Disease Survivors — Final Report

Author

Deen, Gibrilla F., Broutet, Nathalie, Xu, Wenbo, Knust, Barbara, Sesay, Foday R., McDonald, Suzanna L.R., Ervin, Elizabeth, Marrinan, Jaclyn E., Gaillard, Philippe, Habib, Ndema, Liu, Hongtu, Liu, William, Thorson, Anna E., Yamba, Francis, Massaquoi, Thomas A., James, Faustin, Ariyarajah, Archchun, Ross, Christine, Bernstein, Kyle, Coursier, Antoine, Klena, John, Carino, Marylin, Wurie, Alie H., Zhang, Yong, Dumbuya, Marion S., Abad, Neetu, Idriss, Baimba, Wi, Teodora, Bennett, Sarah D., Davies, Tina, Ebrahim, Faiqa K., Meites, Elissa, Naidoo, Dhamari, Smith, Samuel J., Ongpin, Patricia, Malik, Tasneem, Banerjee, Anshu, Erickson, Bobbie R., Liu, Yongjian, Liu, Yang, Xu, Ke, Brault, Aaron, Durski, Kara N., Winter, Jörn, Sealy, Tara, Nichol, Stuart T., Lamunu, Margaret, Bangura, James, Landoulsi, Sihem, Jambai, Amara, Morgan, Oliver, Wu, Guizhen, Liang, Mifang, Su, Qiudong, Lan, Yu, Hao, Yanzhe, Formenty, Pierre, Ströher, Ute, and Sahr, Foday

Published
2017
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41. Hepatitis B Virus and Tuberculosis Are Associated with Increased Noncommunicable Disease Risk among Treatment-Naïve People with HIV: Opportunities for Prevention, Early Detection and Management of Comorbidities in Sierra Leone

Author

Yendewa, George A., primary, Lakoh, Sulaiman, additional, Jiba, Darlinda F., additional, Yendewa, Sahr A., additional, Barrie, Umu, additional, Deen, Gibrilla F., additional, Samai, Mohamed, additional, Jacobson, Jeffrey M., additional, Sahr, Foday, additional, and Salata, Robert A., additional

Published
2022
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42. COVID-19 Vaccine Hesitancy among Healthcare Workers and Trainees in Freetown, Sierra Leone: A Cross-Sectional Study

Author

Yendewa, Sahr A., primary, Ghazzawi, Manal, additional, James, Peter B., additional, Smith, Mohamed, additional, Massaquoi, Samuel P., additional, Babawo, Lawrence S., additional, Deen, Gibrilla F., additional, Russell, James B. W., additional, Samai, Mohamed, additional, Sahr, Foday, additional, Lakoh, Sulaiman, additional, Salata, Robert A., additional, and Yendewa, George A., additional

Published
2022
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43. How Well Are Hand Hygiene Practices and Promotion Implemented in Sierra Leone? A Cross-Sectional Study in 13 Public Hospitals

Author

Lakoh, Sulaiman, primary, Maruta, Anna, additional, Kallon, Christiana, additional, Deen, Gibrilla F., additional, Russell, James B. W., additional, Fofanah, Bobson Derrick, additional, Kamara, Ibrahim Franklyn, additional, Kanu, Joseph Sam, additional, Kamara, Dauda, additional, Molleh, Bailah, additional, Adekanmbi, Olukemi, additional, Tavernor, Simon, additional, Guth, Jamie, additional, Sagili, Karuna D., additional, and Wilkinson, Ewan, additional

Published
2022
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44. High levels of surgical antibiotic prophylaxis: Implications for hospital-based antibiotic stewardship in Sierra Leone

Author

Lakoh, Sulaiman, primary, Kanu, Joseph Sam, additional, Conteh, Sarah K., additional, Russell, James B.W., additional, Sevalie, Stephen, additional, Williams, Christine Ellen Elleanor, additional, Barrie, Umu, additional, Kabia, Aminata Kadie, additional, Conteh, Fatmata, additional, Jalloh, Mohamed Boie, additional, Deen, Gibrilla F., additional, Kabba, Mustapha S., additional, Lebbie, Aiah, additional, Kamara, Ibrahim Franklyn, additional, Fofanah, Bobson Derrick, additional, Maruta, Anna, additional, Kallon, Christiana, additional, Sahr, Foday, additional, Samai, Mohamed, additional, Adekanmbi, Olukemi, additional, Yi, Le, additional, Guo, Xuejun, additional, Kamara, Rugiatu Z., additional, Jiba, Darlinda F., additional, Okeibunor, Joseph Chukwudi, additional, Yendewa, George A., additional, and Firima, Emmanuel, additional

Published
2022
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45. The burden of surgical site infections and related antibiotic resistance in two geographic regions of Sierra Leone: a prospective study

Author

Lakoh, Sulaiman, primary, Yi, Le, additional, Russell, James B.W., additional, Zhang, Juling, additional, Sevalie, Stephen, additional, Zhao, Yongkun, additional, Kanu, Joseph Sam, additional, Liu, Peng, additional, Conteh, Sarah K., additional, Williams, Christine Ellen Elleanor, additional, Barrie, Umu, additional, Sheku, Mohamed Gbessay, additional, Jalloh, Mohamed Boie, additional, Adekanmbi, Olukemi, additional, Jiba, Darlinda F., additional, Kamara, Matilda N., additional, Deen, Gibrilla F., additional, Okeibunor, Joseph Chukwudi, additional, Yendewa, George A., additional, Guo, Xuejun, additional, and Firima, Emmanuel, additional

Published
2022
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46. Characterizing HIV-1 Genetic Subtypes and Drug Resistance Mutations among Children, Adolescents and Pregnant Women in Sierra Leone

Author

Yendewa, George A., primary, Lakoh, Sulaiman, additional, Yendewa, Sahr A., additional, Bangura, Khadijah, additional, Tabernilla, Andrés, additional, Patiño, Lucia, additional, Jiba, Darlinda F., additional, Vandy, Alren O., additional, Massaquoi, Samuel P., additional, Osório, Nuno S., additional, Deen, Gibrilla F., additional, Sahr, Foday, additional, Salata, Robert A., additional, and Poveda, Eva, additional

Published
2021
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47. Assessing eligibility for differentiated service delivery, HIV services utilization and virologic outcomes of adult HIV-infected patients in Sierra Leone: a pre-implementation analysis

Author

Lakoh, Sulaiman, primary, Jiba, Darlinda F., additional, Vandy, Alren O., additional, Poveda, Eva, additional, Adekanmbi, Olukemi, additional, Murray, Mariama J.S., additional, Deen, Gibrilla F., additional, Sahr, Foday, additional, Hoffmann, Christopher J., additional, Jacobson, Jeffrey M., additional, Salata, Robert A., additional, and Yendewa, George A., additional

Published
2021
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