467 results on '"Decher, Niels"'
Search Results
2. Ion occupancy of the selectivity filter controls opening of a cytoplasmic gate in the K2P channel TALK-2
3. Cloxyquin activates hTRESK by allosteric modulation of the selectivity filter
4. Correction: Differential effects of mutations of POPDC proteins on heteromeric interaction and membrane trafficking
5. Differential effects of mutations of POPDC proteins on heteromeric interaction and membrane trafficking
6. Popeye domain containing proteins modulate the voltage-gated cardiac sodium channel Nav1.5
7. Common Structural Pattern for Flecainide Binding in Atrial-Selective Kv1.5 and Nav1.5 Channels: A Computational Approach
8. Novel SK channel positive modulators prevent ferroptosis and excitotoxicity in neuronal cells
9. Sigma-1 receptor modulation fine-tunes KV1.5 channels and impacts pulmonary vascular function
10. KCNQ1 is an essential mediator of the sex-dependent perception of moderate cold temperatures
11. POPDC1 scaffolds a complex of adenylyl cyclase 9 and the potassium channel TREK‐1 in heart
12. Enhanced firing of locus coeruleus neurons and SK channel dysfunction are conserved in distinct models of prodromal Parkinson’s disease
13. A benzodiazepine activator locks Kv7.1 channels open by electro-mechanical uncoupling
14. A novel KCNC3 gene variant in the voltage-dependent Kv3.3 channel in an atypical form of SCA13 with dominant central vertigo.
15. Polypharmacological Modulation of Atrial Fibrillation: Rational Design, Synthesis, and Evaluation of Novel Compounds Targeting NaV1.5, KV1.5, and K2P Channels
16. Ion occupancy of the selectivity filter controls opening of a cytoplasmic gate in the K2P channel TALK-2.
17. POPDC2 a novel susceptibility gene for conduction disorders
18. Enhanced firing of locus coeruleus neurons and SK channel dysfunction are conserved in distinct models of prodromal Parkinson's disease
19. Disease-associated HCN4 V759I variant is not sufficient to impair cardiac pacemaking
20. A lower X-gate in TASK channels traps inhibitors within the vestibule
21. Ion occupancy of the selectivity filter controls opening of a cytoplasmic gate in the K2P channel TALK-2
22. Mutation of the Na+/K+-ATPase Atp1a1a.1 causes QT interval prolongation and bradycardia in zebrafish
23. Severe Arrhythmia Disorder Caused by Cardiac L-Type Calcium Channel Mutations
24. Calcium Handling Remodeling Underlies Impaired Sympathetic Stress Response in Ventricular Myocardium from Cacna1c Haploinsufficient Rats
25. The novel immunosuppressant Cloxyquin activates hTRESK by allosteric modulation of the selectivity filter
26. Characterization of Kv1.2-mediated outward current in TRIP8b-deficient mice
27. Sigma-1 receptor modulation fine-tunes KV1.5 channels and impacts pulmonary vascular function
28. Increased KCNJ18 promoter activity as a mechanism in atypical normokalemic periodic paralysis
29. Mitochondrial damage by α-synuclein causes cell death in human dopaminergic neurons
30. Virtual screening (VS) based in the common binding site for negatively charged activators of K+ channels: A comparison with a pharmacophore-based VS
31. Functional Characterization of a Spectrum of Novel Romano-Ward Syndrome KCNQ1 Variants
32. TASK-1 and TASK-3 may form heterodimers in human atrial cardiomyocytes
33. Gain-of-function mutations in the calcium channel CACNA1C (Cav1.2) cause non-syndromic long-QT but not Timothy syndrome
34. Sodium permeable and “hypersensitive” TREK‐1 channels cause ventricular tachycardia
35. Whole Exome Sequencing Identifies a Heterozygous Variant in the Cav1.3 Gene CACNA1D Associated with Familial Sinus Node Dysfunction and Focal Idiopathic Epilepsy
36. Selective TASK-1 Inhibitor with a Defined Structure–Activity Relationship Reduces Cancer Cell Proliferation and Viability
37. Differential Effects of Mutations of Popeye Domain Containing Proteins on Heteromeric Interaction and Membrane Trafficking
38. A53T-α-synuclein overexpression in murine locus coeruleus induces Parkinson’s disease-like pathology in neurons and glia
39. causes muscular dystrophy and arrhythmia by affecting protein trafficking
40. Electrophysiological characterization of a large set of novel variants in the SCN5A-gene: identification of novel LQTS3 and BrS mutations
41. Hyperinsulinemic Hypoglycemia Associated with a CaV1.2 Variant with Mixed Gain- and Loss-of-Function Effects
42. Mitochondrial Small Conductance SK2 Channels Prevent Glutamate-induced Oxytosis and Mitochondrial Dysfunction
43. A new strategy for multitarget drug discovery/repositioning through the identification of similar 3D amino acid patterns among proteins structures: The case of Tafluprost and its efects on cardiac ion channels
44. Acetylcholine‐dependent upregulation of TASK‐1 channels in thalamic interneurons by a smooth muscle‐like signalling pathway
45. Kv1.5 blockers preferentially inhibit TASK-1 channels: TASK-1 as a target against atrial fibrillation and obstructive sleep apnea?
46. The role of acid-sensitive two-pore domain potassium channels in cardiac electrophysiology: focus on arrhythmias
47. Common Structural Pattern for Flecainide Binding in Atrial-Selective Kv1.5 and Nav1.5 Channels: A Computational Approach
48. A New Strategy for Multitarget Drug Discovery/Repositioning Through the Identification of Similar 3D Amino Acid Patterns Among Proteins Structures: The Case of Tafluprost and its Effects on Cardiac Ion Channels
49. Modulation of Kv1.5 channel expression and function by the sigma 1 receptor
50. A splice variant of the two-pore domain potassium channel TREK-1 with only one pore domain reduces the surface expression of full-length TREK-1 channels
Catalog
Books, media, physical & digital resources
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.