33 results on '"Deborah R. Barnbaum"'
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2. Bibliography
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Deborah R. Barnbaum
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3. Index
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Deborah R. Barnbaum
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4. Voices of Autism: Temple Grandin
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Deborah R. Barnbaum
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5. Voices of Autism: Donna Williams
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Deborah R. Barnbaum
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6. Contents
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Deborah R. Barnbaum
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7. Notes
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Deborah R. Barnbaum
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8. 3 Autism and Moral Theories
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Deborah R. Barnbaum
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9. 4 Autism and Genetic Technologies
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Deborah R. Barnbaum
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10. Voices of Autism: Jim Sinclair
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Deborah R. Barnbaum
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11. 2 The Value of an Autistic Life
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Deborah R. Barnbaum
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12. 1 A Philosophical Introduction to Autism
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Deborah R. Barnbaum
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13. Voices of Autism: Gunilla Gerland
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Deborah R. Barnbaum
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14. Voices of Autism: Wendy Lawson
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Deborah R. Barnbaum
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15. Acknowledgments
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Deborah R. Barnbaum
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16. Randomization Among: The Other Randomization
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Deborah R. Barnbaum
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Research ethics ,medicine.medical_specialty ,Informed Consent ,Health (social science) ,Randomization ,Research Subjects ,business.industry ,Disclosure ,law.invention ,Cohort Studies ,Clinical trial ,Clinical equipoise ,Bias ,Randomized controlled trial ,Informed consent ,law ,Intervention (counseling) ,Family medicine ,Cohort ,Humans ,Medicine ,business ,Randomized Controlled Trials as Topic - Abstract
A valid informed consent process for a randomized controlled trial requires the disclosure to potential participants that they will be randomized to receive the study intervention or a control intervention. This is a case of randomization within a trial, a type of randomization that has received significant attention in research ethics. When institutions recruit large numbers of research participants for multisite clinical trials, a different, hidden form of randomization may occur: randomization among clinical trials. If it is essential to disclose to potential participants randomization within a clinical trial, then it may be the case that randomization among clinical trials recruiting individuals from the same cohort of eligible participants should also be disclosed. This article examines how randomization among clinical trials might take place and the ethical issues such randomization raises about informed consent to research participation.
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- 2019
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17. Compassion-Cultivating Pedagogy: Advancing Social Justice by Improving Social Cognition through Literary Study
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Mark Bracher, Susan Roxburgh, Françoise Massardier-Kenney, Michael Byron, Deborah R. Barnbaum, Tammy Clewell, David Pereplyotchik, Nancy M. Docherty, and Elizabeth M. Smith-Pryor
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media_common.quotation_subject ,MindRxiv|Social and Behavioral Sciences ,050109 social psychology ,Empathy ,Compassion ,MindRxiv|Education ,050105 experimental psychology ,Social cognition ,Pedagogy ,0501 psychology and cognitive sciences ,Narrative ,Situational ethics ,media_common ,MindRxiv|Education|Educational Methods ,05 social sciences ,MindRxiv|Education|Higher Education ,MindRxiv|Arts and Humanities ,General Medicine ,bepress|Education|Educational Methods ,Social justice ,Preference ,Test (assessment) ,bepress|Education ,bepress|Social and Behavioral Sciences ,bepress|Education|Higher Education ,Psychology ,bepress|Arts and Humanities - Abstract
Previous studies suggest that narrative fiction promotes social justice by increasing empathy, but critics have argued that the partiality of empathy severely limits its effectiveness as an engine of social justice, and that what needs to be developed is universal compassion rather than empathy. We created Compassion-Cultivating Pedagogy (CCP) to target the development of two social-cognition capabilities that entail compassion: (1) recognition of self-other overlap and (2) cognizance of the situational, uncontrollable causes of bad character, bad behavior, and bad life-outcomes. Employing a pre/post within- and between-subjects design, we found that students in the CCP classes, but not students in conventionally taught classes, improved in these two areas of social cognition and also exhibited increased preference for compassionate social policies for stigmatized groups. This finding suggests that pedagogy can play a significant role in literature’s contribution to social justice, and that further efforts to develop and test pedagogies for improving social cognition are warranted.
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- 2020
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18. Plasma Vascular Endothelial Growth Factor Concentrations after Intravitreous Anti–Vascular Endothelial Growth Factor Therapy for Diabetic Macular Edema
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Lee M. Jampol, Adam R. Glassman, Danni Liu, Lloyd Paul Aiello, Neil M. Bressler, Elia J. Duh, Susan Quaggin, John A. Wells, Charles C. Wykoff, David Browning, Andrew N. Antoszyk, Angela K. Price, Sherry L. Fredenberg, Jenna T. Herby, Christina J. Fleming, Ashley A. McClain, Sarah A. Ennis, Kelly R. Gallagher, Angella S. Karow, Autumn C. Grupp, Danielle Puskas, Lynn Watson, Swann J. Bojaj, Uma M. Balasubramaniam, Donna McClain, Donna R. Styles, Jeff A. Kuopus, Kathryn Kimrey, Loraine M. Clark, Lisa A. Jackson, Michael D. McOwen, Matt Dunlap, Susannah J. Held, Dante J. Pieramici, Ma'an A. Nasir, Alessandro A. Castellarin, Dilsher Dhoot, Sarah Fishbein, Jack Giust, Lisha Wan, Michelle S. Hanna, Melvin D. Rabena, Jerry Smith, Layne J. Bone, Kelly Avery, Matthew Giust, Aimee Walker, Aimee H. Shook, Sara Esau, Nitce L. Ruvalcaba, W. Lloyd Clark, David L. Johnson, John F. Payne, Tiffany R. Swinford, Mallie M. Taylor, Cassandra L. Garrison, Peggy D. Miller, Amber R. Houlahan, Charlotte A. O'Neill, Ashley Floyd, Crystal C. Parker, Courtney Sease, Tara Graham, Robin Spencer, Tiffany N. Ogbuewu, Ashley Studebaker, Tyler Huggins, Robbin Spivey, Brian Jones, Ashley Williams, Ron Petty, Erin L. Poston, G. Michael Ward, Carl W. Baker, Ron H. Tilford, Tracey M. Caldwell, Lynnette F. Lambert, Mary J. Palmer, Tracey R. Martin, Tana R. Williams, Samantha Kettler, Alecia B. Camp, Paolo S. Silva, Paul G. Arrigg, George S. Sharuk, Sabera T. Shah, Jennifer K. Sun, Corey Westerfeld, Christopher Michael Andreoli, Deborah Schlossman, Timothy Murtha, Hanna Kwak, Flor M. Flores, Margaret E. Stockman, Troy Kieser, Michael N. Krigman, Leila Bestourous, Elizabeth S. Weimann, Jerry D. Cavallerano, Kristen M. Hock, Mary Ann Robertson, Rita K. Kirby, Steve L. Papaconstantinou, Kylie M. Madigan, Robert W. Cavicchi, Kate A. Palitsch, Taygan Yilmaz, Brian B. Berger, Chirag D. Jhaveri, Tori Moore, Ginger J. Manhart, Rachel A. Walsh, Ivana Gunderson, Dietrich Riepen, Chelsey A. Bravenec, Ryan M. Reid, Yong Ren, Ben Ostrander, Christopher C. Stovall, Michael J. Elman, Robert A. Liss, Henry A. Leder, JoAnn Starr, Jennifer L. Belz, Charlene K. Putzulo, Dallas R. Sandler, Jennifer L. Simmons, Pamela V. Singletary, Ashley Davis, Perel M. Simpson, Teresa Coffey, Daniel J. Ketner, Terri Cain, Ashley M. Metzger, Peter Sotirakos, Dennis M. Marcus, Harinderjit Singh, Courtney N. Roberts, Geri L. Floyd, Siobhan O. Ortiz, Virginia Mims, L. Allison Foster, Christy Coursey, Jared C. Gardner, Ken Ivey, John Stewart O'Keefe, Juan A. Astruc, Bryan J. Schwent, Ali R. Tabassian, Suzette A. Rosen, David C. Vaughan, Jeffrey Michaels, Natalie J. Arndt, John J. Maziarz, Scott M. Friedman, Nader Moinfar, Kimberly A. Williamson, Damanda F. Fagan, Katrina L. Dawson, Paige N. Walters, Allen McKinney, Steve Carlton, Robert C. Kwun, Victoria L. Knudsen, Kirk E. Winward, Mano Swartz, James G. Howard, Michelle Riley, Gena Taylor, Michelle Holt, Jason G. Winward, Adam Walsh, Teresa Taylor, Daniel Walsh, G. Robert Hampton, Jamin S. Brown, Rajeev K. Seth, Laurie J. Sienkiewycz, Deborah A. Appleton, Cindy J. Grinnell, Charity A. Cowley, Lynn M. Kwasniewski, Michelle L. Manley, Nicole E. Robarge, Stefanie R. DeSantis, Peter B. Hay, Teresa M. DeForge, Tien P. Wong, Eric Chen, David M. Brown, Rosa Y. Kim, James C. Major, Amy C. Schefler, Richard H. Fish, Matthew S. Benz, Meredith Lipman, Amy Hutson, Nubia Landaverde, Ashley E. Chancey, Cassie Cone, Tressa Royse, Veronica A. Sneed, Belinda A. Almanza, Brenda Dives, Beau A. Richter, Eric N. Kegley, Andreas K. Lauer, Christina J. Flaxel, Steven T. Bailey, Mitchell Schain, Ann D. Lundquist, Shelley A. Hanel, Shirley D. Ira, Susan K. Nolte, Peter N. Steinkamp, Dawn M. Ryan, Scott R. Pickell, Jocelyn T. Hui, Michelle Brix, Jordan Barth, Chris S. Howell, Gregory M. Fox, Blake A. Cooper, Ivan R. Batlle, Lexie R. Manning, Karla A. Batlle, Holly Wyrick, Katherine Pippin, Samantha Perkins, Frank T. Yeager, Ryan B. Rush, Glenn R. Gardner, Christi Rush, Johnathan R. Hawkins, Brenda Dumas, Ben Ysasaga, Chirag P. Shah, Michael G. Morley, Torsten W. Wiegand, Tina S. Cleary, Trexler M. Topping, Lindsey Colegrove, Katharine Bechtel, Britta Johnson, Lisa Lebedew, Natacha Lorius, Sandy G. Chong, Jennifer L. Stone, Michael Cullen Jones, Dennis Donovan, Sherry Malone, Margie Graham, Audrey Santos, Steve A. Bennett, Kevin J. Blinder, Bradley T. Smith, Ginny S. Nobel, Rhonda F. Weeks, Erika A. Hoehn, Maria A. Stuart, Kelly E. Pepple, Lynda K. Boyd, Brook G. Pulliam, Steve A. Schremp, Stephanie L. Guevara, Jarrod Wehmeier, Timothy L. Wright, Dana L. Gabel, David G. Miller, Jerome P. Schartman, Lawrence J. Singerman, Joseph M. Coney, Michael A. Novak, Llewelyn J. Rao, Susan C. Rath, Elizabeth McNamara, Larraine Stone, Veronica A. Smith, Cecelia Rykena, Kimberly A. DuBois, Mary A. Ilc, Vivian Tanner, Kim Drury, Trina M. Nitzsche, Gregg A. Greanoff, John C. DuBois, Stuart K. Burgess, Tirso M. Lara, Noel H. Pereda, Cindy V. Fernandez, Deborah Davis, Evelyn Quinchia, Karen Workman, Jared S. Nielsen, Jeong-Hyeon Sohn, Kyle J. Alliman, David D. Saggau, Marianne Parker, Bethany George, Carrie L. Eastvold, Kristin Sells, Tami Jo Woehl, Marilyn A. Johnson, Holly Keenan, Jennifer L. Coleman, Jamie Spillman, Shannon Freeman, Leigh S. Schmidt, Lisa M. Boender, Jill L. Partin, Bailey R. Bennett, Jay Rostvold, Cameron McLure Stone, Lea R. Raymer, Andrea K. Menzel, Leslie D. Rickman, Barbara Campbell, Lorraine P. Sherlin, Lisa H. Hawkins, Melissa L. Buckner, Olesya N. Matsipura, Paula A. Price, A. Thomas Ghuman, Paul A. Raskauskas, Ashish G. Sharma, Glenn Wing, Joseph P. Walker, Eileen Knips, Cheryl Kiesel, Crystal Y. Peters, Cheryl Ryan, Laura Greenhoe, Natalie N. Torres, Rebecca J. Youngblood, Danielle Turnbo, Anita H. Leslie, Etienne C. Schoeman, Raymond K. Kiesel, Ronald M. Kingsley, Vinay A. Shah, Robert E. Leonard, Heather R. Miller, Sonny Icks, Vanessa A. Bergman, Vanessa K. Drummond, Brittany L. Ross, Reshial D. Ellis, Tina R. Whittington, Shannon R. Almeida, Amanda M. Butt, Russ Burris, Mark A. Peters, Michael S. Lee, Paul S. Tlucek, Colin Ma, Stephen Hobbs, Amanda C. Milliron, Stephanie L. Ho, Marcia Kopfer, Joe Logan, Christine Hoerner, Joseph A. Khawly, Hassan T. Rahman, Diana Abdelgani, Pam S. Miller, Debbie Fredrickson, Erica Pineda, Desiree Lopez, Donald K. Lowd, Colin Blank, Lorena R. Martinez, Jason E. Muniz, Justin Gottlieb, Michael S. Ip, Barbara A. Blodi, Kristine A. Dietzman, Kathryn F. Burke, Christopher M. Smith, Shelly R. Olson, Angela M. Wealti, Sandie L. Reed, Denise A. Krolnik, John C. Peterson, Victor Hugo Gonzalez, Roberto Diaz-Rohena, Juan G. Santiago, Rohit Adyanthaya, Nehal R. Patel, Deyla Anaya, Dina Garcia, Edna E. Cruz, Crystal A. Alvarez, Ruth Iracheta, Jessica Rodriguez, Monica R. Cantu, Rebecca R. Flores, Hector Jasso, Rachel Rodriguez, Karina Miranda, Krystle R. Lozano, Maricela Garza, Lazaro Aguero, Amanda L. Sandoval, Monique Montemayor, Samuel Alonso, Santos Garza, David Allen DiLoreto, Rajeev S. Ramchandran, David M. Kleinman, George W. O'Gara, Andrea M. Czubinski, Peter MacDowell, Kari M. Steinmetz, Dan A. Castillo, Yvonne F. Yu, Salina M. Tongue, Melissa S. Keim, Rachel Hollar, Brandi N. Deats, Brittany S. Richardson, Lynn Singer, Taylor A. Pannell, Stewart A. Daniels, Tushar M. Ranchod, Craig J. Leong, Stacey Touson, Shannon R. Earl, Melissa C. Bartlett, Christine Fernando, Djorella Factor, Jessica Garcia, Anna K. Nguyen, Betty Hom, Cathy Walker, Grace M. Marudo, Jose Carlos Suazo, Leah M. McNeil, Fred Hanamoto, Matthew D. Hughes, Robin D. Ross, Susan M. Sanford, Nicole Martini Markiewicz, Tracy M. Utley, Shannon Henderson, Joanie H. Lippincott, Patricia Streasick, Louis C. Glazer, Frank W. Garber, Jeffrey D. Zheutlin, Angela D. Listerman, Christine E. Feehan, Heather L. Cruz, Donald E. Kuitula, Olivia P. Rainey, Sue Weatherbee, Joseph M. Googe, R. Keith Shuler, Nicholas G. Anderson, Stephen L. Perkins, Kristina Oliver, Nicole Grindall, Ann Arnold, Jennifer Beerbower, Cecile Hunt, Kathy L. Schulz, Sarah M. Oelrich, Jerry K. Whetstone, Justin Walsh, Chris Morris, Robert W. Wong, Peter A. Nixon, Jeni L. Leon, Chris A. Montesclaros, Carrie E. Leung, Phill Le, Codey L. Harborth, Margaret A. Rodriguez, Cory Mangham, Thomas M. Aaberg, Scott J. Westhouse, Holly L. Vincent, Rebecca Malone, Kathy L. Karsten, Raj K. Maturi, Ashley M. Harless, Carolee K. Novak, Laura A. Bleau, Thomas Steele, Charlotte Harris, Alisha Bildner, Abby Maple, Thomas W. Stone, Rick D. Isernhagen, John W. Kitchens, Diana M. Holcomb, Jeanne Van Arsdall, Michelle Buck, Edward A. Slade, Mark T. Chiu, Ashok K. Reddy, Frank W. Wyant, Mary M. Montano-Niles, Lorraine J. Carter, Shirley Maerki, Laura Tartaglia, Paul P. Gomez, Stephen A. Maestas, Camille Shanta, Lisbrenda M. Jimenez, Robert A. Stoltz, Stephanie L. Vanderveldt, Scott I. Lampert, Leslie G. Marcus, Shelly Fulbright, James P. Martin, Roger L. Novack, David S. Liao, Tammy Eileen Lo, Janet Kurokouchi, Richard Ngo, Connie V. Hoang, Julio Sierra, Adam Zamboni, Eric G. Protacio, Jeff Kessinger, Seema Garg, Odette M. Houghton, Jan Niklas Ulrich, Sai H. Chavala, Elizabeth L. DuBose, Cassandra J. Barnhart, Megha Karmalkar, Pooja D. Jani, Justin Goble, Debra Cantrell, Rona Lyn Esquejo, Sandeep N. Shah, Natasha Harmon, Mandeep S. Dhalla, Mario R. del Cid, Lawrence S. Halperin, Jaclyn A. Brady, Monica Hamlin, Monica L. Lopez, Jamie Mariano, Candace M. Neale, Rita R. Veksler, Angelica Mannarelli, Robert E. Coffee, Petros Euthymiou Carvounis, Pejman Hemati, Cindy J. Dorenbach, Annika S. Joshi, April Leger, Dana B. Barnett, Joseph F. Morales, Sam E. Mansour, Cathy Choyce, Aissa L. Dirawatun, Emma A. Nagy, Jamie C. Kerkstra, Joseph T. Fan, Mukesh Bhogilal Suthar, Michael E. Rauser, Gisela Santiago, Liel Marvyn Cerdenio, Brandi J. Perez, Kara E. Halsey, William H. Kiernan, Jesse Knabb, Rachel Catren, Michel Shami, Brenda K. Arrington, Keri S. Neuling, Ashaki Meeks, Natalie R. Garcia, Kayla Blair, Ginger K. Rhymes, Janet Medrano, Judy E. Kim, David V. Weinberg, Kimberly E. Stepien, Thomas B. Connor, Vesper V. Williams, Tracy L. Kaczanowski, Krissa L. Packard, Judy Flanders, Vicki Barwick, Pat A. Winter, Joseph R. Beringer, Kathy J. Selchert, John T. Lehr, Elaine Rodriguez-Roman, Teri Jones, Martha Eileen Haddox, Mark Pena, Brenda Hernandez, Clement K. Chan, Maziar Lalezary, Steven G. Lin, Kimberly S. Walther, Tiana Gonzales, Lenise E. Myers, Kenneth M. Huff, Richard Chace, Sunny Kallay, Kirsten Stevens, Nicole Dolbec, Ronda Baker-Hill, Janea Surette, Steven J. Rose, Brian P. Connolly, Ernest G. Guillet, Edward F. Hall, Margaret M. Yagoda, Mary Jo Doran, Mindy Burgess, Ann Reynard, Margaret Powers, Joe Territo, Calvin E. Mein, Moises A. Chica, R. Gary Lane, Sarah Elizabeth Holy, Lita Kirschbaum, Vanessa D. Martinez, Jaynee Baker, Christa G. Kincaid, Elaine Castillo, Christopher Sean Wienecke, Sara L. Schlichting, Brenda Nakoski, Kenneth R. Diddie, Deborah M. Cadwell, Louise Van Arsdale, Taryn F. Boisvert, Joyce Galonsky, Susie O'Hayer, Melissa L. Johnson, Frank J. McCabe, Brad J. Baker, Melvyn H. Defrin, Marie V. Lampson, Heather Pratte, Selena A. Baron, Aundrea S. Borelli, Frederick H. Davidorf, Michael B. Wells, Susie Chang, John Byron Christoforidis, Alan D. Letson, Jill A. Salerno, Jerilyn G. Perry, Stephen E. Shelley, Patrick J. Fish, Michael H. Scott, James A. Dixon, Shannon R. Walsh, Philomina M. Ozpirincci, Brenda L. Tebon, Marcia J. Moyle, Michael R. Pavlica, Noelle S. Matta, Cristina M. Brubaker, Alyson B. Backer, Neelakshi Bhagat, Catherine Fay, Tatiana Mikheyeva, Michael Lazar, Janie D. Ellenberger, Beth Malpica, Alexander J. Brucker, Benjamin J. Kim, Brian L. VanderBeek, Sheri Drossner, Joan C. DuPont, Rebecca Salvo, Stephanie B. Engelhard, Jim M. Berger, Sara Morales, Beth Serpentine, Paul L. Kaufman, Jessica D. McCluskey, Kathy T. Wynne, Julian Jordan, Brandun Watson, Robert S. Wirthlin, Eric S. Guglielmo, Eileen A. Dittman, Dylan C. Waidelich, Cristofer J. Garza, Adeline M. Stone, Ashley Nicole Oakes, Ivan J. Suner, Mark E. Hammer, Marc C. Peden, Janet R. Traynom, Rochelle DenBoer, Heidi Vargo, Susan Ramsey, Anita Kim Malzahn, Debra Jeffres, Nauman A. Chaudhry, Sumit P. Shah, Gregory M. Haffner, Emiliya German, Shannan Moreau, Laura A. Fox, Jennifer M. Matteson, JoAnna L. Pelletier, Alison Fontecchio, Emily Morse, Greg McNamara, Marie Grace Laglivia, Marissa L. Scherf, Angela LaPre, Justin A. Cocilo, Arup Das, Linda Friesen, Michele Franco, Johnny Lucero, Melissa Frazier, Robert Laviolette, Umar Khalil Mian, Rebecca L. Riemer, Evelyn Koestenblatt, Louise V. Wolf, Christine Kim, Irina Katkovskaya, Erica Otoo, Kevin A. Ellerbe, Kenneth Boyd, Caroline Costa, Paul Andrew Edwards, Hua Gao, Thomas Hessburg, Uday Desai, Janet Murphy, Mary K. Monk, Julianne Hall, Melina Mazurek, Katie M. Ventimiglia, Brian A. Rusinek, Bradley A. Stern, Kris Brouhard, Katie M. Weier, Megan Allis, Jenny Shaken, Nicole M. Massu, Tracy A. Troszak, David Burley, Abdhish R. Bhavsar, Geoffrey G. Emerson, Jacob M. Jones, Tracy A. Anderson, Andrea Gilchrist, Matt D. Peloquin, Gaid Gaid, Yang Vang, Samantha Ryan, Denise Vang, Alanna C. Evans, Tonja Scherer, Howard S. Lazarus, Debra Paige Bunch, Liana C. Davis, Kelly Booth, Margaret Trimble, Mary A. Bledsaw, Jay Moore, Daniel F. Rosberger, Sandra Groeschel, Miriam A. Madry, Nikoletta DiGirolamo, Dustin Pressley, Robert Santora, Yenelda M. Gomez, Karl R. Olsen, Robert L. Bergren, P. William Conrad, Pamela P. Rath, Avni Patel Vyas, Judy C. Liu, Lori A. Merlotti, Jennifer L. Chamberlin, Holly M. Mechling, Mary E. Kelly, Kellianne Marfisi, Kimberly A. Yeckel, Veronica L. Bennett, Christina M. Schultz, Grace A. Rigoni, Julie Walter, Missy A. Forish, Amanda Fec, Courtney L. Foreman, David Steinberg, Keith D. McBroom, Melvin C. Chen, Marc H. Levy, Waldemar Torres, Peggy Jelemensky, Tara L. Raphael, Joann Rich, Mark Sneath, James L. Kinyoun, Gurunadh Atmaram Vemulakonda, Susan A. Rath, Patricia K. Ernst, Juli A. Pettingill, Ronald C. Jones, Brad C. Clifton, James D. Leslie, Sharon D. Solomon, Lisa K. Levin, Deborah Donohue, Mary Frey, Lorena Larez, Keisha Murray, Rita L. Denbow, Janis Graul, David Emmert, Charles Herring, Nick Rhoton, Joe Belz, Alice T. Lyon, Rukhsana G. Mirza, Amanda M. Krug, Carmen Ramirez, Lori Kaminski, Anna Liza M. Castro-Malek, Amber N. Mills, Zuzanna Rozenbajgier, Marriner L. Skelly, Evica Simjanoski, Andrea R. Degillio, Jennifer I. Lim, Felix Y. Chau, Marcia Niec, Tametha Johnson, Yesenia Ovando, Mark Janowicz, Catherine Carroll, Jeffrey G. Gross, Barron C. Fishburne, Amy M. Flowers, Riley Stroman, Christen Ochieng, Angelique S.A. McDowell, Ally M. Paul, Randall L. Price, John H. Drouilhet, Erica N. Lacaden, Deborah J. Nobler, Howard L. Cummings, Deanna Jo Long, Ben McCord, Jason Robinson, Jamie Swift, Julie P. Maynard, Patricia J. Pahk, Hannah Palmer-Dwore, Dipali H. Dave, Mariebelle Pacheco, Barbara A. Galati, Eneil Simpson, Andrew J. Barkmeier, Diane L. Vogen, Karin A. Berg, Shannon L. Howard, Jean M. Burrington, Jessica Ann Morgan, Joan T. Overend, Shannon Goddard, Denise M. Lewison, Jaime L. Tesmer, Craig Michael Greven, Joan Fish, Cara Everhart, Mark D. Clark, David T. Miller, George Baker Hubbard, Jiong Yan, Blaine E. Cribbs, Linda T. Curtis, Judy L. Brower, Jannah L. Dobbs, Debora J. Jordan, Baseer U. Ahmad, Suber S. Huang, Hillary M. Sedlacek, Cherie L. Hornsby, Lisa P. Ferguson, Kathy Carlton, Kelly A. Sholtis, Peggy Allchin, Claudia Clow, Mark A. Harrod, Geoffrey Pankhurst, Irit Baum-Rawraway, Stacie A. Hrvatin, Ronald C. Gentile, Alex Yang, Wanda Carrasquillo-Boyd, Robert Masini, Chander N. Samy, Robert J. Kraut, Kathy Shirley, Linsey Corso, Karen Ely, Elizabeth Scala, Stewart Gross, Vanessa Alava, Eyal Margalit, Donna G. Neely, Maria Blaiotta, Lori Hagensen, April E. Harris, Rita L. Lennon, Denice R. Cota, Larry Wilson, Lloyd P. Aiello, Roy W. Beck, Susan B. Bressler, Kakarla V. Chalam, Ronald P. Danis, Bambi J. Arnold-Bush, Frederick Ferris, Talat Almukhtar, Brian B. Dale, Alyssa Baptista, Crystal Connor, Jasmine Conner, Sharon R. Constantine, Kimberly Dowling, Simone S. Dupre, Allison R. Ayala, Meagan L. Huggins, Seidu Inusah, Paula A. Johnson, Brenda L. Loggins, Shannon L. McClellan, Michele Melia, Eureca Battle, Cynthia R. Stockdale, Danielle Stanley, Glenn Jaffe, Brannon Balsley, Michael Barbas, Russell Burns, Dee Busian, Ryan Ebersohl, Cynthia Heydary, Sasha McEwan, Justin Myers, Amanda Robertson, Kelly Shields, Garrett Thompson, Katrina Winter, Ellen Young, Matthew D. Davis, Yijun Huang, Barbara Blodi, Amitha Domalpally, James Reimers, Pamela Vargo, Hugh Wabers, Dawn Myers, Daniel Lawrence, James Allan, Andrew Antoszyk, Scott Friedman, Ingrid U. Scott, Eleanor Schron, Donald F. Everett, Päivi H. Miskala, John Connett, Gary Abrams, Deborah R. Barnbaum, Harry Flynn, Ruth S. Weinstock, Charles P. Wilkinson, Stephen Wisniewski, Saul Genuth, Robert Frank, Frederick L. Ferris, Glenn J. Jaffe, Abdhish Bhavsar, Joseph Googe, Andreas Lauer, and Ashley McClain
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Male ,Vascular Endothelial Growth Factor A ,medicine.medical_specialty ,Visual acuity ,genetic structures ,Bevacizumab ,Recombinant Fusion Proteins ,Visual Acuity ,030232 urology & nephrology ,Angiogenesis Inhibitors ,Enzyme-Linked Immunosorbent Assay ,Gastroenterology ,Macular Edema ,Article ,law.invention ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Randomized controlled trial ,law ,Ranibizumab ,Internal medicine ,medicine ,Humans ,Stroke ,Aflibercept ,Diabetic Retinopathy ,business.industry ,Middle Aged ,medicine.disease ,Confidence interval ,Vascular endothelial growth factor ,Ophthalmology ,Receptors, Vascular Endothelial Growth Factor ,Treatment Outcome ,chemistry ,Intravitreal Injections ,Retreatment ,030221 ophthalmology & optometry ,Female ,medicine.symptom ,business ,Tomography, Optical Coherence ,Follow-Up Studies ,medicine.drug - Abstract
PURPOSE: Assess systemic vascular endothelial growth factor-A (VEGF) levels after treatment with intravitreous aflibercept, bevacizumab or ranibizumab. DESIGN: Comparative-effectiveness trial with participants randomly assigned to 2-mg aflibercept, 1.25-mg bevacizumab, or 0.3-mg ranibizumab following a retreatment algorithm. PARTICIPANTS: Participants with available plasma samples (N=436) METHODS: Plasma samples were collected before injections at baseline, 4-week, 52-week and 104-week visits. In a pre-planned secondary analysis, systemic free-VEGF levels from an ELISA immunoassay were compared across anti-VEGF agents and correlated with systemic side effects. MAIN OUTCOME MEASURES: Changes in the natural log (ln) of plasma VEGF levels. RESULTS: Baseline free-VEGF levels were similar across all 3 groups. At 4 weeks, mean ln(VEGF) changes were −0.30±0.61, −0.31±0.54, −0.02±0.44 pg/ml for the aflibercept, bevacizumab, and ranibizumab groups, respectively. The adjusted differences between treatment groups (adjusted CI; P-value) were −0.01 (−0.12, +0.10; P=0.89), −0.31 (−0.44, −0.18; P
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- 2018
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19. Data Safety Monitoring during Covid‐19: Keep On Keeping On
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Deborah R. Barnbaum
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Health (social science) ,Research Subjects ,Pneumonia, Viral ,MEDLINE ,Health(social science) ,Betacoronavirus ,Patient safety ,Informed consent ,Pandemic ,medicine ,Humans ,Pandemics ,Computer Security ,Safety monitoring ,Clinical Trials as Topic ,Informed Consent ,biology ,SARS-CoV-2 ,business.industry ,COVID-19 ,biology.organism_classification ,medicine.disease ,Immunization ,Commentary ,Medical emergency ,Clinical Trials Data Monitoring Committees ,Coronavirus Infections ,Risk assessment ,business - Published
- 2020
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20. Drawing Distinctions Among Different Types of Research on Persons with Autism
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Deborah R. Barnbaum
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medicine ,Autism ,Psychology ,medicine.disease ,Developmental psychology - Abstract
This commentary engages two aspects of Kenneth A. Richman’s chapter “Autism, Autonomy, and Research” (Chapter 5). First, several excellent points made in the chapter are discussed. Second, a distinction is introduced among types of research on persons with autism, a distinction that would strengthen his discussion. Drawing distinctions among the ways in which informed consent is confounded by symptoms of autism, as well as among types of research on autism, would further strengthen an already compelling chapter.
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- 2019
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21. The Mindset of Surrogates and Inclusivity Research
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Deborah R. Barnbaum
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Mindset ,Environmental ethics ,Psychology - Abstract
This commentary considers three aspects of Britteny Howell and Karrie Shogren’s chapter “Differing Understandings of Informed Consent Held by Research Institutions, People With Intellectual Disability, and Guardians: Implications for Inclusive, Ethical Research” (Chapter 3). First, strengths of their discussion are considered. Second, a philosophical distinction amongst three justifications for surrogate decisions is elaborated upon, and is used conceptually to ground claims in Howell and Shogren’s chapter. Finally, it is suggested that illustrating this distinction to surrogate decision-makers may bolster the participation of persons with intellectual disabilities in research.
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- 2019
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22. Research Cohorts
- Author
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Deborah R. Barnbaum
- Abstract
Some people with cognitive disabilities are perceived to have compromised autonomy and thus unable to consent to research participation. Individuals without cognitive disabilities are assumed to have the capacity to consent, despite falling prey to errors such as the therapeutic misconception, unrealistic optimism, or a lack of appreciation. The distinction between conceptual errors made by presumably “typical” individuals and those made by individuals with cognitive impairments may not be so different, and differences that do exist not so profound. Best practices call for a “meeting in the middle”—a recognition that “typical” individuals are not nearly as autonomous as we first think, and that the autonomy of “atypical” individuals is not as compromised as first appears. Two objections to this conclusion are addressed: exploitation, and a history of research abuses. Respecting persons with cognitive impairments means recognizing that their imperfect autonomy is not dissimilar from the imperfect autonomy of others.
- Published
- 2019
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23. Sellars and Contemporary Philosophy
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David Pereplyotchik, Deborah R. Barnbaum, David Pereplyotchik, and Deborah R. Barnbaum
- Subjects
- B945.S444
- Abstract
Wilfrid Sellars made profound and lasting contributions to nearly every area of philosophy. The aim of this collection is to highlight the continuing importance of Sellars'work to contemporary debates. The contributors include several luminaries in Sellars scholarship, as well as members of the new generation whose work demonstrates the lasting power of Sellars'ideas. Papers by O'Shea and Koons develop Sellars'underexplored views concerning ethics, practical reasoning, and free will, with an emphasis on his longstanding engagement with Kant. Sachs, Hicks and Pereplyotchik relate Sellars'views of mental phenomena to current topics in cognitive science and philosophy of mind. Fink, deVries, Price, Macbeth, Christias, and Brandom grapple with traditional Sellarsian themes, including meaning, truth, existence, and objectivity. Brandhoff provides an original account of the evolution of Sellars'philosophy of language and his project of'pure pragmatics'. The volume concludes with an author-meets-critics section centered around Robert Brandom's recent book, From Empiricism to Expressivism: Brandom Reads Sellars, with original commentaries and replies.
- Published
- 2016
24. Sellars and Contemporary Philosophy
- Author
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Deborah R. Barnbaum and David Pereplyotchik
- Subjects
Philosophy of language ,Philosophy of sport ,Contemporary philosophy ,Philosophy ,Metaphysics ,Western philosophy ,Philosophy education ,Epistemology - Published
- 2016
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25. Supererogation in clinical research
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Deborah R. Barnbaum
- Subjects
Moral Obligations ,Health (social science) ,Patients ,Research Subjects ,Normative ethics ,Health Personnel ,media_common.quotation_subject ,Medical law ,Morals ,Ethics, Research ,Education ,Humans ,Medicine ,Duty ,media_common ,Supererogation ,Research ethics ,business.industry ,Health Policy ,Altruism (ethics) ,Bioethics ,Altruism ,Research Personnel ,Epistemology ,Ethics, Clinical ,Philosophy of medicine ,business - Abstract
'Supererogation' is the notion of going beyond the call of duty. The concept of supererogation has received scrutiny in ethical theory, as well as clinical bioethics. Yet, there has been little attention paid to supererogation in research ethics. Supererogation is examined in this paper from three perspectives: (1) a summary of two analyses of 'supererogation' in moral theory, as well as an examination as to whether acts of supererogation exist; (2) a discussion of supererogation in clinical practice, including arguments that both physicians and patients can practice acts of supererogation; (3) a discussion as to why researchers, qua researchers, are not routinely recognized to perform acts of supererogation, while at the same time the very nature of research subject participation involves supererogation. The article concludes by considering three examples of supererogation on the part of researchers, with a plea that researchers' supererogatory actions be recognized as such.
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- 2008
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26. Teaching Empathy in Medical Ethics
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Deborah R. Barnbaum
- Subjects
media_common.quotation_subject ,Compassion ,State of affairs ,Empathy ,Education ,Simulation theory of empathy ,Philosophy ,Embodied cognition ,Sympathy ,Sociology ,Social psychology ,Medical ethics ,media_common ,Mental image - Abstract
M. Gordon counts transforming oneself via an “imaginative shift” as one of the higher forms of empathy. 1 The mental imaging that an actor uses to transform himself from a person playing a role into the character the actor is supposed to represent is one example of this imaginative shift. The actor is no longer a person who presents himself as someone pretending to be someone else; the actor presents himself as the character he represents. The empathy embodied in the imaginative shift allows an actor to become a better actor by allowing the actor to capture what a character’s responses would be in a particular dramatic setting. Empathy in medicine is at least as valuable as empathy in performance. 2 Empathy, also called “compassion,” is celebrated by Beauchamp and Childress as one of the “four focal virtues” of medicine. Beauchamp and Childress define compassion as “a trait combining an attitude of active regard for another’s welfare with an imaginative awareness and emotional response of deep sympathy, tenderness, and discomfort at the other person’s (or animal’s) misfortune or suffering.” 3 But how can we teach empathy and its importance for arriving at a considered decision in medical ethics? Empathy may strike us initially as a gift: one is born with an ability to respond empathetically to others, or one is born without that talent. The possibility that empathy is an unteachable talent may strike others as a dire state of affairs, rather than merely “unfortunate.” If empathy is invaluable in medical ethics, we should seek some means of teaching empathy to others. If empathy is a talent, and one that cannot be taught, then some students’ abilities to successfully analyze cases in medical ethics may be permanently compromised. The result is that some patients may be receiving substandard care from health care practitioners
- Published
- 2001
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27. The FDA's Proposal for Public Disclosure of Adverse Events in Gene Therapy Trials
- Author
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Deborah R. Barnbaum
- Subjects
Risk ,Genetic Research ,medicine.medical_specialty ,Public Administration ,Sociology and Political Science ,Genetic enhancement ,Transplantation, Heterologous ,Alternative medicine ,Guidelines as Topic ,Disclosure ,Food and drug administration ,Informed consent ,medicine ,Animals ,Humans ,Family ,Public disclosure ,Genetic Privacy ,Intensive care medicine ,Adverse effect ,Clinical Trials as Topic ,Informed Consent ,United States Food and Drug Administration ,business.industry ,Community Participation ,Genetic Therapy ,Public relations ,United States ,Group Processes ,Clinical trial ,Germ Cells ,Human Experimentation ,Clinical research ,Government Regulation ,Public Health ,business ,Social Sciences (miscellaneous) - Abstract
In January 2001, the Food and Drug Administration (FDA) proposed annual public disclosure of adverse events during gene therapy and xenotransplantation trials. The proposed policy raises the following questions: (1) Is the reformed policy in accord with the FDA's long-standing informed consent policies? (2) Why pair gene therapy trials and xenotransplantation trials in the revised guidelines? (3) Why single out these trials for public disclosure of adverse events? Each question is examined, and three conclusions are drawn. First, the FDA's own policies on informed consent require prompter public disclosure of adverse events. Second, the coupling of gene therapy and xenotransplantation trials entails a conceptual mistake in the types of communities that are harmed by each therapy's related adverse events. Third, all clinical trials merit such public disclosure of adverse events, not only gene therapy and xenotransplantation trials.
- Published
- 2000
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28. Interpreting Surrogate Consent using Counterfactuals
- Author
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Deborah R. Barnbaum
- Subjects
Philosophy ,Counterfactual conditional ,business.industry ,Interpretation (philosophy) ,Health care ,Psychology ,Best interests ,Directive ,business ,Counterexample ,Epistemology - Abstract
Philosophers such as Dan Brock believe that surrogates who make health care decisions on behalf of previously competent patients, in the absence of an advance directive, should make these decisions based upon a substituted judgment principle. Brock favours substituted judgment over a best interests standard. However, Edward Wierenga claims that the substituted judgment principle ought to be abandoned in favour of a best interests standard, because of an inherent problem with the substituted judgment principle. Wierenga's version of the substituted judgment principle and his counterexample to the principle's successful interpretation of valid surrogate consent is presented. A new version of what is meant by the substituted judgment principle is advanced. The new version is not beset with the problems Wierenga initially ascribed to the substituted judgment principle.
- Published
- 1999
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29. Ex post facto IRB review: two practical hurdles, one conceptual mistake
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Deborah R, Barnbaum
- Subjects
Human Experimentation ,Informed Consent ,Time Factors ,Humans ,Ethical Review ,Risk Assessment ,Ethics Committees, Research - Published
- 2004
30. The Ethics of Autism: Among Them, but Not of Them
- Author
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Deborah R. Barnbaum and Deborah R. Barnbaum
- Published
- 2012
31. Bioethics, Ellen Frankel Paul, Fred D. Miller, Jr, and Jeffrey Paul, editors
- Author
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Deborah R. Barnbaum
- Subjects
Public Administration ,Sociology and Political Science ,biology ,Philosophy ,Miller ,Bioethics ,Positive economics ,Religious studies ,biology.organism_classification ,Social Sciences (miscellaneous) - Published
- 2004
- Full Text
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32. Except for all the others
- Author
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Deborah R. Barnbaum
- Subjects
General Medicine ,General Biochemistry, Genetics and Molecular Biology - Published
- 2011
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33. Making More Sense of 'Minimal Risk'
- Author
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Deborah R. Barnbaum
- Subjects
Health (social science) ,Harm ,Absolute sense ,Government regulation ,Minimal risk ,Prima facie ,Product (category theory) ,Sense (electronics) ,Risk assessment ,Psychology ,Law and economics - Abstract
Some clarification is required to understand this definition. First, it should be clear that risk and harm are not the same concepts. Beauchamp and Childress note that harm is the "normatively neutral sense of thwarting, defeating, or setting back the interests of one party by causes that include self-harming conditions as well as the (intentional or unintentional) actions of another party."3 Thus though they may not be bad in an absolute sense, harms are, in general, perceived as prima facie wrong to inflict on others.4 Risk is "commonly expressed as the magnitude of some harm multiplied by the probability of its occurrence,"s and can be represented in the following product formula
- Published
- 2002
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