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4 results on '"Deary, Katryna B."'

1. Neuroinflammation at the Grey-White Matter Interface in Active-Duty United States Special Operations Forces

Author

Edlow, Brian L, primary, Tseng, Chieh-En J, additional, Gilmore, Natalie, additional, McKinney, Isabella R, additional, Tromly, Samantha L, additional, Deary, Katryna B, additional, Hu, Collin G, additional, Healy, Brian C, additional, Mac Donald, Christine L, additional, Dams-O'Connor, Kristen, additional, Greve, Douglas N, additional, Bodien, Yelena G, additional, Perl, Daniel P, additional, Hooker, Jacob M, additional, and Zürcher, Nicole R, additional

Published
2024
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2. Impact of repeated blast exposure on active-duty United States Special Operations Forces.

Author

Gilmore, Natalie, Chieh-En J. Tseng, Maffei, Chiara, Tromly, Samantha L., Deary, Katryna B., McKinney, Isabella R., Kelemen, Jessica N., Healy, Brian C., Hu, Collin G., Ramos-Llordén, Gabriel, Masood, Maryam, Cali, Ryan J., Guo, Jennifer, Belanger, Heather G., Yao, Eveline F., Baxter, Timothy, Fischl, Bruce, Foulkes, Andrea S., Polimeni, Jonathan R., and Rosen, Bruce R.

Subjects
EXPOSURE therapy, POSITRON emission tomography, EXECUTIVE function, DIFFUSION magnetic resonance imaging, PREFRONTAL cortex, TRANSLOCATOR proteins
Abstract

United States (US) Special Operations Forces (SOF) are frequently exposed to explosive blasts in training and combat, but the effects of repeated blast exposure (RBE) on SOF brain health are incompletely understood. Furthermore, there is no diagnostic test to detect brain injury from RBE. As a result, SOF personnel may experience cognitive, physical, and psychological symptoms for which the cause is never identified, and they may return to training or combat during a period of brain vulnerability. In 30 active-duty US SOF, we assessed the relationship between cumulative blast exposure and cognitive performance, psychological health, physical symptoms, blood proteomics, and neuroimaging measures (Connectome structural and diffusion MRI, 7 Tesla functional MRI, [11C]PBR28 translocator protein [TSPO] positron emission tomography [PET]-MRI, and [18F]MK6240 tau PET-MRI), adjusting for age, combat exposure, and blunt head trauma. Higher blast exposure was associated with increased cortical thickness in the left rostral anterior cingulate cortex (rACC), a finding that remained significant after multiple comparison correction. In uncorrected analyses, higher blast exposure was associated with worse health-related quality of life, decreased functional connectivity in the executive control network, decreased TSPO signal in the right rACC, and increased cortical thickness in the right rACC, right insula, and right medial orbitofrontal cortex--nodes of the executive control, salience, and default mode networks. These observations suggest that the rACC may be susceptible to blast overpressure and that a multimodal, network-based diagnostic approach has the potential to detect brain injury associated with RBE in active-duty SOF. [ABSTRACT FROM AUTHOR]

Published
2024
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3. Optimizing Brain Health of United States Special Operations Forces

Author

Edlow, Brian L, primary, Gilmore, Natalie, additional, Tromly, Samantha L, additional, Deary, Katryna B, additional, McKinney, Isabella R, additional, Hu, Collin G, additional, Kelemen, Jessica N, additional, Maffei, Chiara, additional, Tseng, Chieh-En J, additional, Llorden, Gabriel R, additional, Healy, Brian C, additional, Masood, Maryam, additional, Cali, Ryan J, additional, Baxter, Timothy, additional, Yao, Eveline F, additional, Belanger, Heather G, additional, Benjamini, Dan, additional, Basser, Peter J, additional, Priemer, David S, additional, Kimberly, W. T, additional, Polimeni, Jonathan R, additional, Rosen, Bruce R, additional, Fischl, Bruce, additional, Zurcher, Nicole R, additional, Greve, Douglas N, additional, Hooker, Jacob M, additional, Huang, Susie Y, additional, Caruso, Adam, additional, Smith, Gregory A, additional, Szymanski, Timothy G, additional, Perl, Daniel P, additional, Dams-O'Connor, Kristen, additional, Mac Donald, Christine L, additional, and Bodien, Yelena G, additional

Published
2023
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4. Long-Term Effects of Repeated Blast Exposure in United States Special Operations Forces Personnel: A Pilot Study Protocol

Author

Edlow, Brian L., primary, Bodien, Yelena G., additional, Baxter, Timothy, additional, Belanger, Heather G., additional, Cali, Ryan J., additional, Deary, Katryna B., additional, Fischl, Bruce, additional, Foulkes, Andrea S., additional, Gilmore, Natalie, additional, Greve, Douglas N., additional, Hooker, Jacob M., additional, Huang, Susie Y., additional, Kelemen, Jessica N., additional, Kimberly, W. Taylor, additional, Maffei, Chiara, additional, Masood, Maryam, additional, Perl, Daniel P., additional, Polimeni, Jonathan R., additional, Rosen, Bruce R., additional, Tromly, Samantha L., additional, Tseng, Chieh-En J., additional, Yao, Eveline F., additional, Zürcher, Nicole R., additional, Mac Donald, Christine L., additional, and Dams-O'Connor, Kristen, additional

Published
2022
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