15,978 results on '"Deangelis, A."'
Search Results
2. An AI Wishlist from School Leaders
- Author
-
Raffaella Borasi, David E. Miller, Patricia Vaughan-Brogan, Karen DeAngelis, Yu Jung Han, and Sharon Mason
- Abstract
To better understand the current challenges surrounding the use of artificial intelligence (AI) in K-12 schools, a team of researchers (Raffaella Borasi, David E. Miller, Patricia Vaughan-Brogan, Karen DeAngelis, Yu Jung Han, and Sharon Mason) interviewed 36 western New York school leaders in late 2023. Their concerns moved beyond potential cheating, as they instead identified four main priorities: receiving guidance to inform their decisions about AI, empowering all stakeholders to better understand AI and its implications, capitalizing on AI to support the work of teachers and staff, and enabling better technology solutions. These should inform future interventions aiming at leveraging AI in K-12 education.
- Published
- 2024
- Full Text
- View/download PDF
3. Boundary regularity for the Mumford-Shah functional with Dirichlet boundary conditions
- Author
-
Deangelis, Francesco
- Subjects
Mathematics - Analysis of PDEs ,49Q20, 49N60 - Abstract
In this paper we consider minimizers of the Mumford-Shah functional with Dirichlet boundary conditions. We study blow-ups at the boundary and prove an epsilon-regularity theorem.
- Published
- 2024
4. Ocular manifestations and long-term complications of rhabdomyosarcoma in children
- Author
-
Graef, Sybille, DeAngelis, Dan, Gupta, Abha A., and Wan, Michael J.
- Published
- 2024
- Full Text
- View/download PDF
5. Effect of Tear Size and Location on Supraspinatus Tendon Strain During Activities of Daily Living and Physiotherapy
- Author
-
Garcia, Mason, Landi, Gabriel, Covan, Bailee, Caro, Daniela, Khak, Mohammad, Razavi, Ahmad Hedayatzadeh, DeAngelis, Joseph P., Ramappa, Arun J., and Nazarian, Ara
- Published
- 2024
- Full Text
- View/download PDF
6. `Spatial patterns as long transients in submersed-floating plant competition with biocontrol
- Author
-
Xu, Linhao and DeAngelis, Donald L.
- Published
- 2024
- Full Text
- View/download PDF
7. The Effects of Regulations on Private School Choice Program Participation: Experimental Evidence from the United States
- Author
-
DeAngelis, Corey A., Burke, Lindsey M., Wolf, Patrick J., and Dills, Angela K.
- Abstract
Private school leaders weigh costs and benefits when deciding whether to participate in school voucher programs. Regulatory costs associated with accepting voucher funding could reduce private school leaders' willingness to participate. We test this hypothesis through the first random assignment analysis of the effects of various regulations on the expressed willingness of private school leaders to participate in hypothetical voucher programs that draws upon national data. We randomly assign different regulations to U.S. private school leaders and ask them whether they would participate in a hypothetical school voucher program during the following school year. Relative to no regulations, we find that open-enrollment mandates reduce the likelihood that private school leaders report being certain to participate in a hypothetical choice program by about 14 percentage points, or 67%. The requirement that private schools accept the voucher funding amount as payment-in-full reduces the likelihood that private school leaders report being certain to participate by 16 percentage points, or 77%. Some regulations are more likely to deter private schools with higher reported tuitions, higher enrollment trends, more specialization, and more climate problems.
- Published
- 2023
8. Priorities, opportunities, and challenges for integrating microorganisms into Earth system models for climate change prediction.
- Author
-
Lennon, JT, Abramoff, RZ, Allison, SD, Burckhardt, RM, DeAngelis, KM, Dunne, JP, Frey, SD, Friedlingstein, P, Hawkes, CV, Hungate, BA, Khurana, S, Kivlin, SN, Levine, NM, Manzoni, S, Martiny, AC, Martiny, JBH, Nguyen, NK, Rawat, M, Talmy, D, Todd-Brown, K, Vogt, M, Wieder, WR, and Zakem, EJ
- Subjects
Biochemistry and Cell Biology ,Biomedical and Clinical Sciences ,Biological Sciences ,Microbiology ,Medical Microbiology ,Generic health relevance ,Climate Action ,biogeochemistry ,modeling ,traits ,climate change ,Biochemistry and cell biology ,Medical microbiology - Abstract
Climate change jeopardizes human health, global biodiversity, and sustainability of the biosphere. To make reliable predictions about climate change, scientists use Earth system models (ESMs) that integrate physical, chemical, and biological processes occurring on land, the oceans, and the atmosphere. Although critical for catalyzing coupled biogeochemical processes, microorganisms have traditionally been left out of ESMs. Here, we generate a "top 10" list of priorities, opportunities, and challenges for the explicit integration of microorganisms into ESMs. We discuss the need for coarse-graining microbial information into functionally relevant categories, as well as the capacity for microorganisms to rapidly evolve in response to climate-change drivers. Microbiologists are uniquely positioned to collect novel and valuable information necessary for next-generation ESMs, but this requires data harmonization and transdisciplinary collaboration to effectively guide adaptation strategies and mitigation policy.
- Published
- 2024
9. Beyond the Requirement: A Novel Patient-Follow Up Report
- Author
-
Schreyer, Kraftin, Allan, Jack, Repanshek, Zachary, Healy, Megan, DeAngelis, Michael, Satz, Wayne, and Ufberg, Jacob
- Published
- 2024
10. Transient grating spectroscopy on a DyCo$_5$ thin film with femtosecond extreme ultraviolet pulses
- Author
-
Ukleev, Victor, Leroy, Ludmila, Mincigrucci, Riccardo, Deangelis, Dario, Fainozzi, Danny, Khatu, Nupur Ninad, Paltanin, Ettore, Foglia, Laura, Bencivenga, Filippo, Luo, Chen, Ruske, Florian, Radu, Florin, Svetina, Cristian, and Staub, Urs
- Subjects
Condensed Matter - Materials Science ,Condensed Matter - Mesoscale and Nanoscale Physics - Abstract
Surface acoustic waves (SAWs) are excited by femtosecond extreme ultraviolet (EUV) transient gratings (TGs) in a room-temperature ferrimagnetic DyCo$_5$ alloy. TGs are generated by crossing a pair of EUV pulses from a free electron laser (FEL) with the wavelength of 20.8\,nm matching the Co $M$-edge, resulting in a SAW wavelength of $\Lambda=44$\,nm. Using the pump-probe transient grating scheme in a reflection geometry the excited SAWs could be followed in the time range of -10 to 100\,ps in the thin film. Coherent generation of TGs by ultrafast EUV pulses allows to excite SAW in any material and to investigate their couplings to other dynamics such as spin waves and orbital dynamics. In contrast, we encountered challenges in detecting electronic and magnetic signals, potentially due to the dominance of the larger SAW signal and the weakened reflection signal from underlying layers. A potential solution for the latter challenge involves employing soft X-ray probes, albeit introducing additional complexities associated with the required grazing incidence geometry.
- Published
- 2023
- Full Text
- View/download PDF
11. Ecological benefits of integrative weed management of Melaleuca quinquenervia in Big Cypress National Preserve
- Author
-
Smith, Melissa C., Julian, Paul, DeAngelis, Don, and Zhang, Bo
- Published
- 2024
- Full Text
- View/download PDF
12. Preclinical dose response study shows NR2E3 can attenuate retinal degeneration in the retinitis pigmentosa mouse model RhoP23H+/−
- Author
-
McNamee, Shannon M., Chan, Natalie P., Akula, Monica, Avola, Marielle O., Whalen, Maiya, Nystuen, Kaden, Singh, Pushpendra, Upadhyay, Arun K., DeAngelis, Margaret M., and Haider, Neena B.
- Published
- 2024
- Full Text
- View/download PDF
13. Microbial responses to long-term warming differ across soil microenvironments
- Author
-
Liu, Xiao Jun A, Han, Shun, Frey, Serita D, Melillo, Jerry M, Zhou, Jizhong, and DeAngelis, Kristen M
- Subjects
Microbiology ,Biological Sciences ,Ecology ,Climate Action ,carbon storage and sequestration ,bacterial necromass ,substrate accessibility ,biogeochemical cycles ,soil aggregation ,microbial evolution ,organic matter decomposition ,functional genomics ,degradation enzymes ,plant soil interactions - Abstract
Soil carbon loss is likely to increase due to climate warming, but microbiomes and microenvironments may dampen this effect. In a 30-year warming experiment, physical protection within soil aggregates affected the thermal responses of soil microbiomes and carbon dynamics. In this study, we combined metagenomic analysis with physical characterization of soil aggregates to explore mechanisms by which microbial communities respond to climate warming across different soil microenvironments. Long-term warming decreased the relative abundances of genes involved in degrading labile compounds (e.g. cellulose), but increased those genes involved in degrading recalcitrant compounds (e.g. lignin) across aggregate sizes. These changes were observed in most phyla of bacteria, especially for Acidobacteria, Actinobacteria, Bacteroidetes, Chloroflexi, and Planctomycetes. Microbial community composition was considerably altered by warming, leading to declined diversity for bacteria and fungi but not for archaea. Microbial functional genes, diversity, and community composition differed between macroaggregates and microaggregates, indicating the essential role of physical protection in controlling microbial community dynamics. Our findings suggest that microbes have the capacity to employ various strategies to acclimate or adapt to climate change (e.g. warming, heat stress) by shifting functional gene abundances and community structures in varying microenvironments, as regulated by soil physical protection.
- Published
- 2024
14. Machine learning with taxonomic family delimitation aids in the classification of ephemeral beaked whale events in passive acoustic monitoring.
- Author
-
Solsona-Berga, Alba, DeAngelis, Annamaria, Cholewiak, Danielle, Trickey, Jennifer, Mueller-Brennan, Liam, Frasier, Kaitlin, Van Parijs, Sofie, and Baumann-Pickering, Simone
- Subjects
Animals ,Whales ,Acoustics ,Vocalization ,Animal ,Machine Learning ,Neural Networks ,Computer - Abstract
Passive acoustic monitoring is an essential tool for studying beaked whale populations. This approach can monitor elusive and pelagic species, but the volume of data it generates has overwhelmed researchers ability to quantify species occurrence for effective conservation and management efforts. Automation of data processing is crucial, and machine learning algorithms can rapidly identify species using their sounds. Beaked whale acoustic events, often infrequent and ephemeral, can be missed when co-occurring with signals of more abundant, and acoustically active species that dominate acoustic recordings. Prior efforts on large-scale classification of beaked whale signals with deep neural networks (DNNs) have approached the class as one of many classes, including other odontocete species and anthropogenic signals. That approach tends to miss ephemeral events in favor of more common and dominant classes. Here, we describe a DNN method for improved classification of beaked whale species using an extensive dataset from the western North Atlantic. We demonstrate that by training a DNN to focus on the taxonomic family of beaked whales, ephemeral events were correctly and efficiently identified to species, even with few echolocation clicks. By retrieving ephemeral events, this method can support improved estimation of beaked whale occurrence in regions of high odontocete acoustic activity.
- Published
- 2024
15. Genome-wide association identifies novel ROP risk loci in a multiethnic cohort
- Author
-
Li, Xiaohui, Owen, Leah A, Taylor, Kent D, Ostmo, Susan, Chen, Yii-Der Ida, Coyner, Aaron S, Sonmez, Kemal, Hartnett, M Elizabeth, Guo, Xiuqing, Ipp, Eli, Roll, Kathryn, Genter, Pauline, Chan, RV Paul, DeAngelis, Margaret M, Chiang, Michael F, Campbell, J Peter, and Rotter, Jerome I
- Subjects
Biological Sciences ,Biomedical and Clinical Sciences ,Genetics ,Ophthalmology and Optometry ,Human Genome ,Biotechnology ,Eye Disease and Disorders of Vision ,Perinatal Period - Conditions Originating in Perinatal Period ,Prevention ,Pediatric ,Rare Diseases ,Clinical Research ,Aetiology ,2.1 Biological and endogenous factors ,Eye ,Infant ,Newborn ,Humans ,Genome-Wide Association Study ,Retinopathy of Prematurity ,Ethnicity ,Genetic Predisposition to Disease ,Polymorphism ,Single Nucleotide ,i-ROP Consortium ,Biological sciences ,Biomedical and clinical sciences - Abstract
We conducted a genome-wide association study (GWAS) in a multiethnic cohort of 920 at-risk infants for retinopathy of prematurity (ROP), a major cause of childhood blindness, identifying 1 locus at genome-wide significance level (p
- Published
- 2024
16. Traces of Historical Redlining in the Contemporary United States: New Evidence from the Add Health Cohort
- Author
-
DeAngelis, Reed T., Frizzelle, Brian G., Hummer, Robert A., and Harris, Kathleen Mullan
- Published
- 2024
- Full Text
- View/download PDF
17. Evaluating therapeutic potential of NR2E3 doses in the rd7 mouse model of retinal degeneration
- Author
-
McNamee, Shannon M., Akula, Monica, Love, Zoe, Nasraty, Neelaab, Nystuen, Kaden, Singh, Pushpendra, Upadhyay, Arun K., DeAngelis, Margaret M., and Haider, Neena B.
- Published
- 2024
- Full Text
- View/download PDF
18. Modelling COVID-19 transmission dynamics in Laos under non-pharmaceutical interventions, vaccination, and replacement of SARS-CoV-2 variants
- Author
-
Zhang, Xu-Sheng, Luo, Hong, Charlett, Andre, DeAngelis, Daniela, Liu, Wei, Vickerman, Peter, Woolhouse, Mark, and Wu, Linxiong
- Published
- 2024
- Full Text
- View/download PDF
19. Biobehavioral and affective stress responses during nicotine withdrawal: Influence of regular cannabis co-use
- Author
-
al’Absi, Mustafa, DeAngelis, Briana N., Nakajima, Motohiro, Hodges, James S., Budney, Alan, Hatsukami, Dorothy, and Allen, Sharon
- Published
- 2024
- Full Text
- View/download PDF
20. Religious Involvement and Allostatic Resilience: Findings from a Community Study of Black and White Americans
- Author
-
DeAngelis, Reed, Upenieks, Laura, and Louie, Patricia
- Published
- 2024
- Full Text
- View/download PDF
21. Evaluating therapeutic potential of NR2E3 doses in the rd7 mouse model of retinal degeneration
- Author
-
Shannon M. McNamee, Monica Akula, Zoe Love, Neelaab Nasraty, Kaden Nystuen, Pushpendra Singh, Arun K. Upadhyay, Margaret M. DeAngelis, and Neena B. Haider
- Subjects
Gene replacement ,AAV ,Retinitis pigmentosa ,rd7 ,Mouse ,Electroretinography ,Medicine ,Science - Abstract
Abstract Retinitis Pigmentosa is a leading cause of severe vision loss. Retinitis Pigmentosa can present with a broad range of phenotypes impacted by disease age of onset, severity, and progression. This variation is influenced both by different gene mutations as well as unique variants within the same gene. Mutations in the nuclear hormone receptor 2 family e, member 3 are associated with several forms of retinal degeneration, including Retinitis Pigmentosa. In our previous studies we demonstrated that subretinal administration of one Nr2e3 dose attenuated retinal degeneration in rd7 mice for at least 3 months. Here we expand the studies to evaluate the efficacy and longitudinal impact of the NR2E3 therapeutic by examining three different doses administered at early or intermediate stages of retinal degeneration in the rd7 mice. Our study revealed retinal morphology was significantly improved 6 months post for all doses in the early-stage treatment groups and for the low and mid doses in the intermediate stage treatment groups. Similarly, photoreceptor function was significantly improved in the early stage for all doses and intermediate stage low and mid dose groups 6 months post treatment. This study demonstrated efficacy in multiple doses of NR2E3 therapy.
- Published
- 2024
- Full Text
- View/download PDF
22. Modelling COVID-19 transmission dynamics in Laos under non-pharmaceutical interventions, vaccination, and replacement of SARS-CoV-2 variants
- Author
-
Xu-Sheng Zhang, Hong Luo, Andre Charlett, Daniela DeAngelis, Wei Liu, Peter Vickerman, Mark Woolhouse, and Linxiong Wu
- Subjects
Bayesian estimation ,Control measures ,COVID-19 ,SARS-CoV-2 ,Oxford Government COVID-19 policy index ,Google mobility ,Public aspects of medicine ,RA1-1270 - Abstract
Abstract Background Understanding how the COVID-19 pandemic evolved under control measures is crucial to tackle the SARS-CoV-2 virus spread. Laos, a country bordering China but with late occurrence and low burden of COVID-19 compared to its neighbouring countries, was used for a case study. Methods A transmission model with disease reporting was proposed to investigate the impact of control measures on the SARS-CoV-2 virus spread in Laos from April 2021 to May 2022. It was assumed that the transmission rate changed with people’s behaviours, control measures and emerging variants; susceptibility decreased with vaccination and infection. Bayesian inference was used for model calibration to data of confirmed cases, deaths, and recoveries, and the deviance information criterion was used to select the best model variant. Results Our model including Non-pharmaceutical interventions (NPIs), behaviour change, vaccination, and changing variants well explained the three waves in Laos. The Alpha variant was estimated to have a basic reproduction number of 1.55 (95% CrI: 1.47–1.64) and was replaced by the Delta variant from September 2021 which was 1.88 (95% CrI: 1.77–2.01) times more transmissible; the Delta variant was replaced by Omicron variant from March 2022 which was 3.33 (95% CrI: 2.84–3.74) times more transmissible. The Delta variant was the most severe with a case fatality rate of 1.05% (95% CrI: 0.96–1.15%) while the Alpha variant and Omicron variant were much milder. The ascertainment rate was low and variable: first decreasing from 13.2 to 1.8% by 23 May 2021, and then increasing to 23.4% by 15 March 2022. Counterfactual simulations indicated that vaccination played strong roles in reducing infections even under the emergence of immune escape variants while behaviour change delayed but might not flatten the peak of outbreaks. Conclusions The three waves of Laos’ epidemics were due to the invasion of more transmissible and immune escape variants that affected the herd immunity built via vaccination and infection. Even with immunity waning and the escape of new variants, vaccination was still the major contributor to control COVID-19 and combining behaviour changes and vaccination would best suppress future outbreaks of COVID-19.
- Published
- 2024
- Full Text
- View/download PDF
23. 2020 ASCO, 2023 NCCN, 2023 MASCC/ESMO, and 2019 CCO: a comparison of antiemetic guidelines for the treatment of chemotherapy-induced nausea and vomiting in cancer patients
- Author
-
Kennedy, Samantha K. F., Goodall, Shannon, Lee, Shing Fung, DeAngelis, Carlo, Jocko, Allison, Charbonneau, Flay, Wang, Katie, Pasetka, Mark, Ko, Yoo-Joung, Wong, Henry C. Y., Chan, Adrian Wai, Rajeswaran, Thenugaa, Gojsevic, Milena, Chow, Edward, Gralla, Richard J., Ng, Terry L., and Jerzak, Katarzyna J.
- Published
- 2024
- Full Text
- View/download PDF
24. Fear of a Black Neighborhood: Anti-Black Racism and the Health of White Americans
- Author
-
Louie, Patricia and DeAngelis, Reed T.
- Published
- 2024
25. ECLAPTE: Effective Closure of LAParoTomy in Emergency-2023 World Society of Emergency Surgery guidelines for the closure of laparotomy in emergency settings.
- Author
-
Frassini, Simone, Cobianchi, Lorenzo, Fugazzola, Paola, Biffl, Walter, Coccolini, Federico, Damaskos, Dimitrios, Moore, Ernest, Kluger, Yoram, Ceresoli, Marco, Coimbra, Raul, Davies, Justin, Kirkpatrick, Andrew, Di Carlo, Isidoro, Hardcastle, Timothy, Isik, Arda, Chiarugi, Massimo, Gurusamy, Kurinchi, Maier, Ronald, Segovia Lohse, Helmut, Jeekel, Hans, Boermeester, Marja, Abu-Zidan, Fikri, Inaba, Kenji, Weber, Dieter, Augustin, Goran, Bonavina, Luigi, Velmahos, George, Sartelli, Massimo, Di Saverio, Salomone, Ten Broek, Richard, Granieri, Stefano, Dal Mas, Francesca, Farè, Camilla, Peverada, Jacopo, Zanghì, Simone, Viganò, Jacopo, Tomasoni, Matteo, Dominioni, Tommaso, Cicuttin, Enrico, Hecker, Andreas, Tebala, Giovanni, Galante, Joseph, Wani, Imtiaz, Khokha, Vladimir, Sugrue, Michael, Scalea, Thomas, Tan, Edward, Malangoni, Mark, Pararas, Nikolaos, Podda, Mauro, De Simone, Belinda, Ivatury, Rao, Cui, Yunfeng, Kashuk, Jeffry, Peitzman, Andrew, Kim, Fernando, Pikoulis, Emmanouil, Sganga, Gabriele, Chiara, Osvaldo, Kelly, Michael, Marzi, Ingo, Picetti, Edoardo, Agnoletti, Vanni, DeAngelis, Nicola, Campanelli, Giampiero, de Moya, Marc, Litvin, Andrey, Martínez-Pérez, Aleix, Sall, Ibrahima, Rizoli, Sandro, Tomadze, Gia, Sakakushev, Boris, Stahel, Philip, Civil, Ian, Shelat, Vishal, Costa, David, Chichom-Mefire, Alain, Latifi, Rifat, Chirica, Mircea, Amico, Francesco, Pardhan, Amyn, Seenarain, Vidya, Boyapati, Nikitha, Hatz, Basil, Ackermann, Travis, Abeyasundara, Sandun, Fenton, Linda, Plani, Frank, Sarvepalli, Rohit, Rouhbakhshfar, Omid, Caleo, Pamela, Ho-Ching Yau, Victor, Clement, Kristenne, Christou, Erasmia, Castillo, Ana, Gosal, Preet, Balasubramaniam, Sunder, Hsu, Jeremy, Banphawatanarak, Kamon, and Pisano, Michele
- Subjects
Abdominal wall incision ,Closure technique ,Emergency ,Incisional hernia ,Laparotomy closure ,Midline incision ,Wound complications ,Wound dehiscence ,Humans ,Laparotomy ,Abdominal Wound Closure Techniques ,Suture Techniques ,Incisional Hernia ,Reoperation - Abstract
Laparotomy incisions provide easy and rapid access to the peritoneal cavity in case of emergency surgery. Incisional hernia (IH) is a late manifestation of the failure of abdominal wall closure and represents frequent complication of any abdominal incision: IHs can cause pain and discomfort to the patients but also clinical serious sequelae like bowel obstruction, incarceration, strangulation, and necessity of reoperation. Previous guidelines and indications in the literature consider elective settings and evidence about laparotomy closure in emergency settings is lacking. This paper aims to present the World Society of Emergency Surgery (WSES) project called ECLAPTE (Effective Closure of LAParoTomy in Emergency): the final manuscript includes guidelines on the closure of emergency laparotomy.
- Published
- 2023
26. Management of complicated diaphragmatic hernia in the acute setting: a WSES position paper.
- Author
-
Giuffrida, Mario, Perrone, Gennaro, Abu-Zidan, Fikri, Agnoletti, Vanni, Ansaloni, Luca, Baiocchi, Gian, Bendinelli, Cino, Biffl, Walter, Bonavina, Luigi, Bravi, Francesca, Carcoforo, Paolo, Ceresoli, Marco, Chichom-Mefire, Alain, Coccolini, Federico, Coimbra, Raul, deAngelis, Nicola, de Moya, Marc, De Simone, Belinda, Di Saverio, Salomone, Fraga, Gustavo, Ivatury, Rao, Kashuk, Jeffry, Kelly, Michael, Kirkpatrick, Andrew, Kluger, Yoram, Koike, Kaoru, Leppaniemi, Ari, Maier, Ronald, Moore, Ernest, Peitzmann, Andrew, Sakakushev, Boris, Sartelli, Massimo, Sugrue, Michael, Tian, Brian, Broek, Richard, Vallicelli, Carlo, Wani, Imtaz, Weber, Dieter, Docimo, Giovanni, Catena, Fausto, and Galante, Joseph
- Subjects
Congenital ,Diaphragm hernia ,Emergency surgery ,Guidelines ,Rupture ,Trauma ,Humans ,Diaphragm ,Hernias ,Diaphragmatic ,Congenital ,Tomography ,X-Ray Computed ,Thorax ,Hernia ,Hiatal ,Thoracic Injuries - Abstract
BACKGROUND: Diaphragmatic hernia (DH) presenting acutely can be a potentially life-threatening condition. Its management continues to be debatable. METHODS: A bibliographic search using major databases was performed using the terms emergency surgery diaphragmatic hernia, traumatic diaphragmatic rupture and congenital diaphragmatic hernia. GRADE methodology was used to evaluate the evidence and give recommendations. RESULTS: CT scan of the chest and abdomen is the diagnostic gold standard to evaluate complicated DH. Appropriate preoperative assessment and prompt surgical intervention are important for a clinical success. Complicated DH repair is best performed via the use of biological and bioabsorbable meshes which have proven to reduce recurrence. The laparoscopic approach is the preferred technique in hemodynamically stable patients without significant comorbidities because it facilitates early diagnosis of small diaphragmatic injuries from traumatic wounds in the thoraco-abdominal area and reduces postoperative complications. Open surgery should be reserved for situations when skills and equipment for laparoscopy are not available, where exploratory laparotomy is needed, or if the patient is hemodynamically unstable. Damage Control Surgery is an option in the management of critical and unstable patients. CONCLUSIONS: Complicated diaphragmatic hernia is a rare life-threatening condition. CT scan of the chest and abdomen is the gold standard for diagnosing the diaphragmatic hernia. Laparoscopic repair is the best treatment option for stable patients with complicated diaphragmatic hernias. Open repair is considered necessary in majority of unstable patients in whom Damage Control Surgery can be life-saving.
- Published
- 2023
27. Assessing and managing frailty in emergency laparotomy: a WSES position paper.
- Author
-
Tian, Brian, Stahel, Philip, Picetti, Edoardo, Campanelli, Giampiero, Di Saverio, Salomone, Moore, Ernest, Bensard, Denis, Sakakushev, Boris, Galante, Joseph, Fraga, Gustavo, Koike, Kaoru, Di Carlo, Isidoro, Tebala, Giovanni, Leppaniemi, Ari, Tan, Edward, Damaskos, Dimitris, DeAngelis, Nicola, Hecker, Andreas, Pisano, Michele, Maier, Ron, De Simone, Belinda, Amico, Francesco, Ceresoli, Marco, Pikoulis, Manos, Weber, Dieter, Biffl, Walt, Beka, Solomon, Abu-Zidan, Fikri, Valentino, Massimo, Coccolini, Federico, Kluger, Yoram, Sartelli, Massimo, Agnoletti, Vanni, Chirica, Mircea, Bravi, Francesca, Sall, Ibrahima, and Catena, Fausto
- Subjects
Elderly ,Emergency surgery ,Frail ,Frailty ,Laparotomy ,Humans ,Aged ,Aged ,80 and over ,Frailty ,Laparotomy ,Frail Elderly ,Consensus ,Comorbidity - Abstract
Many countries are facing an aging population. As people live longer, surgeons face the prospect of operating on increasingly older patients. Traditional teaching is that with older age, these patients face an increased risk of mortality and morbidity, even to a level deemed too prohibitive for surgery. However, this is not always true. An active 90-year-old patient can be much fitter than an overweight, sedentary 65-year-old patient with comorbidities. Recent literature shows that frailty-an age-related cumulative decline in multiple physiological systems, is therefore a better predictor of mortality and morbidity than chronological age alone. Despite recognition of frailty as an important tool in identifying vulnerable surgical patients, many surgeons still shun objective tools. The aim of this position paper was to perform a review of the existing literature and to provide recommendations on emergency laparotomy and in frail patients. This position paper was reviewed by an international expert panel composed of 37 experts who were asked to critically revise the manuscript and position statements. The position paper was conducted according to the WSES methodology. We shall present the derived statements upon which a consensus was reached, specifying the quality of the supporting evidence and suggesting future research directions.
- Published
- 2023
28. Teachers Unions Inadvertently Ignited the Year of School Choice
- Author
-
American Enterprise Institute (AEI), Conservative Education Reform Network (CERN) and DeAngelis, Corey
- Abstract
Through their response to the pandemic, teachers unions overplayed their hand and exposed inherent failures of the one-size-fits-all government school system. Families are now thankfully figuring out that there isn't any good reason to fund institutions when they can fund students directly instead. Support for school choice is through the roof, making 2021 the year of school choice. Eighteen states enacted or expanded programs to fund students instead of systems this year. The number of states with education savings account programs--the purest form of funding students directly and empowering families--doubled from five to 10 this year. The power imbalance between the public school monopoly and families was made clearer than ever. Parents were willing to put up with their children's schools receiving taxpayer money while failing to adequately meet their needs year after year. But it became another thing entirely when those schools took that money but refused to provide in-person service. The public school system's version of virtual learning was a failure for many children, academically and socially. At the same time, remote instruction allowed families to get a closer look at what was going on in their classrooms, and many parents weren't happy with what they viewed to be ideological indoctrination. This unexpected increase in transparency further fueled parents' calls for more control over their children's educations. The latest battles over curriculum, masking, and reopening are all symptoms of the problem that is the one-size-fits-all government school system. Thankfully, more people are now seeing that the best solution to these problems is funding students directly.
- Published
- 2021
29. Nicotine addiction and the influence of life adversity and acute stress on PYY: Prediction of early smoking relapse
- Author
-
Amanda A. Miller, Motohiro Nakajima, Briana N. DeAngelis, Dorothy K. Hatsukami, and Mustafa al'Absi
- Subjects
acute stress ,appetite hormones ,early life adversity ,peptide YY ,relapse ,smoking ,Therapeutics. Pharmacology ,RM1-950 - Abstract
Abstract Early life adversity (ELA) is associated with earlier initiation and maintenance of tobacco smoking and with a greater risk of subsequent relapse. There is growing evidence that appetite hormones, including peptide YY (PYY), which modulates craving and satiety responses, play a role in stress and addiction processes. This study employed a quasi‐experimental design to examine the association between ELA and circulating PYY stress responses in smokers and nonsmokers (N = 152, ages 19–73 years) to examine the effects of nicotine addiction. Smokers initiated a quit attempt as part of the study and were classified as either abstinent smokers or relapsed smokers based on their nicotine use during the follow‐up period. PYY levels were measured at five timepoints during three lab sessions and compared between nonsmokers and the two smoking groups (abstainers, relapsers): while smokers were using nicotine ad libitum, 24 h after smokers initiated a quit attempt, and 4 weeks after smokers initiated a quit attempt. Multivariate analyses showed the main effects of time on PYY, which decreased over time within each session. The main effects of ELA during the first (ad libitum smoking) and second (24‐h post‐cessation for smokers) sessions indicated that experiencing ELA was associated with lower PYY. No systematic effect of nicotine addiction or relapse was observed in this study. These findings suggest that adults with higher ELA may experience lower PYY. Additional research is needed to further explore the role of PYY in stress and addiction processes.
- Published
- 2024
- Full Text
- View/download PDF
30. SanctSound: Building Data Systems for Sound Decisions
- Author
-
Hatch, Leila, Barkowski, Jack, Baumann-Pickering, Simone, Bell, Carrie Wall, Best, Benjamin, Brown, Jennifer, DeAngelis, Annamaria, Joseph, John, Kim, Ella, Kitchen, Danielle, Kok, Annebelle C. M., Kügler, Anke, Kumar, Anurag, Lammers, Marc O., Margolina, Tetyana, McKenna, Megan, Merkens, Karlina, Reeves, Lindsey Peavey, Rowell, Timothy J., Shoemaker, Mandy, Stanley, Jenni A., Stimpert, Alison, Southall, Brandon, Stone, Brian, Tartt, Mitchell, Van Parijs, Sofie, Zang, Eden J., Popper, Arthur N., Section editor, Popper, Arthur N., editor, Sisneros, Joseph A., editor, Hawkins, Anthony D., editor, and Thomsen, Frank, editor
- Published
- 2024
- Full Text
- View/download PDF
31. Charter School Funding: Dispelling Myths about EMOs, Expenditure Patterns, & Nonpublic Dollars
- Author
-
University of Arkansas, School Choice Demonstration Project (SCDP), Dills, Angela K., Wolf, Patrick J., DeAngelis, Corey A., May, Jay F., Maloney, Larry D., and Syftestad, Cassidy
- Abstract
Three decades after the first charter school law passed in the United States, myths about these public schools not only persist but continue to fuel strong claims and divisive debates. Commentators point to education management organizations (EMOs), for-profit organizations which manage or operate a network of charter schools, as examples of private entities supposedly profiting off public education. In this report, the authors dispel three common myths about charter schools and their funding, spending, and management. They draw upon comprehensive school funding data collected from traditional public schools (TPS) and public charter schools in 18 cities during fiscal year (FY) 2018.
- Published
- 2021
32. Point defect distributions in ultrafast laser-induced periodic surface structures on β-Ga2O3.
- Author
-
Ramdin, Daram N., DeAngelis, Emma, Noor, Mohamed Yaseen, Haseman, Micah S., Chowdhury, Enam A., and Brillson, Leonard J.
- Subjects
- *
FEMTOSECOND lasers , *POINT defects , *SURFACE structure , *OPTICAL properties , *CATHODOLUMINESCENCE , *KELVIN probe force microscopy , *IRRADIATION - Abstract
β-Ga2O3 has received widespread attention due to its ultrawide bandgap, which potentially permits applications in extreme conditions. Ultrafast laser irradiation of β-Ga2O3 provides a means for exploring the response of the material under such conditions, which could result in the generation of point defects as well as a localized modification of structural features that could yield properties that differ from the pristine surface. However, an understanding of defects generated by femtosecond laser irradiation in the vicinity of laser-induced periodic surface structures (LIPSS) remains to be explored. We correlate topographic features with optical and electronic properties by combining near-nm scale resolution cathodoluminescence with Kelvin probe force microscopy. Defects are found to correlate with crystalline order and near-surface morphology, as well as changes in work function. They are also suggested to be closely related to the formation of high spatial frequency LIPSS. These results suggest a need for precise tuning of laser irradiation conditions as well as possible post-processing to control defects in future Ga2O3 devices. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
33. Point defect distributions in ultrafast laser-induced periodic surface structures on β-Ga2O3.
- Author
-
Ramdin, Daram N., DeAngelis, Emma, Noor, Mohamed Yaseen, Haseman, Micah S., Chowdhury, Enam A., and Brillson, Leonard J.
- Subjects
FEMTOSECOND lasers ,POINT defects ,SURFACE structure ,OPTICAL properties ,CATHODOLUMINESCENCE ,KELVIN probe force microscopy ,IRRADIATION - Abstract
β-Ga
2 O3 has received widespread attention due to its ultrawide bandgap, which potentially permits applications in extreme conditions. Ultrafast laser irradiation of β-Ga2 O3 provides a means for exploring the response of the material under such conditions, which could result in the generation of point defects as well as a localized modification of structural features that could yield properties that differ from the pristine surface. However, an understanding of defects generated by femtosecond laser irradiation in the vicinity of laser-induced periodic surface structures (LIPSS) remains to be explored. We correlate topographic features with optical and electronic properties by combining near-nm scale resolution cathodoluminescence with Kelvin probe force microscopy. Defects are found to correlate with crystalline order and near-surface morphology, as well as changes in work function. They are also suggested to be closely related to the formation of high spatial frequency LIPSS. These results suggest a need for precise tuning of laser irradiation conditions as well as possible post-processing to control defects in future Ga2 O3 devices. [ABSTRACT FROM AUTHOR]- Published
- 2024
- Full Text
- View/download PDF
34. Substrate availability and not thermal acclimation controls microbial temperature sensitivity response to long‐term warming
- Author
-
Domeignoz‐Horta, Luiz A, Pold, Grace, Erb, Hailey, Sebag, David, Verrecchia, Eric, Northen, Trent, Louie, Katherine, Eloe‐Fadrosh, Emiley, Pennacchio, Christa, Knorr, Melissa A, Frey, Serita D, Melillo, Jerry M, and DeAngelis, Kristen M
- Subjects
Biological Sciences ,Ecology ,Climate Action ,Temperature ,Soil Microbiology ,Acclimatization ,Soil ,Carbon ,carbon use efficiency ,climate change ,microbial temperature sensitivity ,microbial thermal acclimation ,soil carbon cycling ,Environmental Sciences ,Biological sciences ,Earth sciences ,Environmental sciences - Abstract
Microbes are responsible for cycling carbon (C) through soils, and predicted changes in soil C stocks under climate change are highly sensitive to shifts in the mechanisms assumed to control the microbial physiological response to warming. Two mechanisms have been suggested to explain the long-term warming impact on microbial physiology: microbial thermal acclimation and changes in the quantity and quality of substrates available for microbial metabolism. Yet studies disentangling these two mechanisms are lacking. To resolve the drivers of changes in microbial physiology in response to long-term warming, we sampled soils from 13- and 28-year-old soil warming experiments in different seasons. We performed short-term laboratory incubations across a range of temperatures to measure the relationships between temperature sensitivity of physiology (growth, respiration, carbon use efficiency, and extracellular enzyme activity) and the chemical composition of soil organic matter. We observed apparent thermal acclimation of microbial respiration, but only in summer, when warming had exacerbated the seasonally-induced, already small dissolved organic matter pools. Irrespective of warming, greater quantity and quality of soil carbon increased the extracellular enzymatic pool and its temperature sensitivity. We propose that fresh litter input into the system seasonally cancels apparent thermal acclimation of C-cycling processes to decadal warming. Our findings reveal that long-term warming has indirectly affected microbial physiology via reduced C availability in this system, implying that earth system models including these negative feedbacks may be best suited to describe long-term warming effects on these soils.
- Published
- 2023
35. Is Irreligion a Risk Factor for Suicidality? Findings from the Nashville Stress and Health Study
- Author
-
Daniels, Colton L., Ellison, Christopher G., DeAngelis, Reed T., and Klee, Katherine
- Published
- 2023
- Full Text
- View/download PDF
36. Making It Count: The Productivity of Public Charter Schools in Seven U.S. Cities
- Author
-
University of Arkansas, School Choice Demonstration Project (SCDP), DeAngelis, Corey A., Wolf, Patrick J., Syftestad, Cassidy, Maloney, Larry D., and May, Jay F.
- Abstract
Charter schools are publicly funded schools freed from some of the regulations placed on traditional public schools (TPS). In exchange for that greater level of autonomy, public charter schools are required to meet performance goals contained in their authorizing charter or face the prospect of closure. Most public charter schools may enroll students from a wide geographic area, not just a neighborhood school zone. Such "independent" or "open enrollment" charter schools must admit students by lottery if oversubscribed. Over 7,500 public charter schools enrolled over 3.3 million students during the 2018-19 school year. The researchers of this report examine the differences in cost-effectiveness and return-on-investment (ROI) for public charter schools and traditional public schools (TPS) in seven major U.S. cities: Camden, Denver, Indianapolis, Shelby County (Memphis), New Orleans, San Antonio, and the District of Columbia. They determine how much money is invested in public charter schools and TPS, what levels of student achievement are attained across the two public school sectors, and how much economic payoff society can expect to receive as a result of the educational investments in each sector.
- Published
- 2021
37. The Direct and Indirect Effects of Engagement on Desired Outcomes for First-Year Students with Learning Disabilities
- Author
-
Zilvinskis, John, Taub, Deborah J., Novi, Alyson M., DeAngelis, Benjamin J., and Wilson, Kaedynne E.
- Abstract
Finding pathways to success for students with disabilities is important to the work of administrators and educators who wish to support this population. Guided by an anti-deficit framework and the minority group model, data from the 2015 and 2016 administration of the National Survey of Student Engagement were examined to learn how Engagement Indicators related to outcomes (GPA, satisfaction, and self-reported learning) for over fifteen thousand first-year students with disabilities. To avoid deficit framing, structural equation modeling was employed to measure the mediation effects of four Engagement Indicators for students with learning disabilities compared to other students with disabilities. Results from this study indicate that most Engagement Indicators are significantly, and in some cases strongly, related to outcomes for students with disabilities; however, only Student-Faculty Interaction was a significant, positive mediator for students with learning disabilities whereas the significant negative mediators indicate that engagement has divergent effects for students with disabilities.
- Published
- 2023
- Full Text
- View/download PDF
38. Resource-Driven Pattern Formation in Consumer-Resource Systems with Asymmetric Dispersal on a Plane.
- Author
-
Weiting Song, Shikun Wang, Yuanshi Wang, and Donald L. DeAngelis
- Published
- 2024
- Full Text
- View/download PDF
39. The Collaborative Nature of Testimonial Learning.
- Author
-
Pearl Han Li, Erika R. DeAngelis, Norwood Glaspie, and Melissa A. Koenig
- Published
- 2024
- Full Text
- View/download PDF
40. Risk factors affecting the utilization of eye care services evaluated by the CDC's behavior risk factor surveillance system from 2018 to 2021
- Author
-
Adrianna M. Powers, Deepkumar Patel, Margaret M. DeAngelis, Changyong Feng, and Karen Allison
- Subjects
diabetic retinopathy ,glaucoma ,eye care utilization ,quality of life ,health disparities ,risk factors ,Public aspects of medicine ,RA1-1270 - Abstract
When thinking about major health concerns in the U.S. and around the world, eye care ranks lower compared to cardiovascular disease, cancer, and diabetes. However, people do not think about the direct connection between diabetes and eye health. Untreated diabetes can lead to visual impairments such as blindness or difficulty seeing. Studies have found that eye health associated with nutrition, occupational exposure, diabetes, high blood pressure, and heart disease are some of the known risk factors. This study aimed to identify the potential risk factors that are associated with visual impairment (VI). The data used for this analysis were obtained from the Centers for Disease Control and Prevention (CDC) - Behavioral Risk Factor Surveillance System (BRFSS) from 2018 to 2021. We found important characteristics, such as the U.S. region, general health perception, employment status, income status, age, and health insurance source, that are associated with VI. Our study confirmed that the common demographical factors including age, race/ethnicity, the U.S. region, and gender are associated with VI. The study also highlights associations with additional risk factors such as health insurance source, general health perceptions, employment status, and income status. Using this information, we can reach out to communities with large numbers of individuals experiencing vision challenges and help educate them on prevention and treatment protocols, thereby effectively addressing VI and blindness challenges within our communities, neighborhoods, and finally, the broader society.
- Published
- 2024
- Full Text
- View/download PDF
41. Priorities, opportunities, and challenges for integrating microorganisms into Earth system models for climate change prediction
- Author
-
J. T. Lennon, R. Z. Abramoff, S. D. Allison, R. M. Burckhardt, K. M. DeAngelis, J. P. Dunne, S. D. Frey, P. Friedlingstein, C. V. Hawkes, B. A. Hungate, S. Khurana, S. N. Kivlin, N. M. Levine, S. Manzoni, A. C. Martiny, J. B. H. Martiny, N. K. Nguyen, M. Rawat, D. Talmy, K. Todd-Brown, M. Vogt, W. R. Wieder, and E. J. Zakem
- Subjects
biogeochemistry ,modeling ,traits ,climate change ,Microbiology ,QR1-502 - Abstract
ABSTRACTClimate change jeopardizes human health, global biodiversity, and sustainability of the biosphere. To make reliable predictions about climate change, scientists use Earth system models (ESMs) that integrate physical, chemical, and biological processes occurring on land, the oceans, and the atmosphere. Although critical for catalyzing coupled biogeochemical processes, microorganisms have traditionally been left out of ESMs. Here, we generate a “top 10” list of priorities, opportunities, and challenges for the explicit integration of microorganisms into ESMs. We discuss the need for coarse-graining microbial information into functionally relevant categories, as well as the capacity for microorganisms to rapidly evolve in response to climate-change drivers. Microbiologists are uniquely positioned to collect novel and valuable information necessary for next-generation ESMs, but this requires data harmonization and transdisciplinary collaboration to effectively guide adaptation strategies and mitigation policy.
- Published
- 2024
- Full Text
- View/download PDF
42. Disaggregating the Engagement of Students of Color with Disabilities
- Author
-
Zilvinskis, John, Taub, Deborah J., DeAngelis, Benjamin J., Novi, Alyson M., and Wilson, Kaedynne E.
- Abstract
Quantitative researchers often account for aspects of identity such as race, ethnicity, and disability separately in their analyses. However, scholars have called for a critical approach to these data by disaggregating underserved student groups to better understand the experience of these students. In the current study, we analyzed data from the National Survey of Student Engagement of 16,327 first-year students with disabilities through effect coding, multilevel modeling, and multiple regression analysis to measure engagement patterns related to race and ethnicity. Significant patterns related to the engagement of students of color with disabilities emerged among the dependent variables of "higher-order learning," "student-faculty interaction," and "supportive environment."
- Published
- 2021
43. Acute mesenteric ischemia: updated guidelines of the World Society of Emergency Surgery.
- Author
-
Bala, Miklosh, Catena, Fausto, Kashuk, Jeffry, De Simone, Belinda, Gomes, Carlos, Weber, Dieter, Sartelli, Massimo, Coccolini, Federico, Kluger, Yoram, Abu-Zidan, Fikri, Picetti, Edoardo, Ansaloni, Luca, Augustin, Goran, Biffl, Walter, Ceresoli, Marco, Chiara, Osvaldo, Chiarugi, Massimo, Coimbra, Raul, Cui, Yunfeng, Damaskos, Dimitris, Di Saverio, Salomone, Khokha, Vladimir, Kirkpatrick, Andrew, Inaba, Kenji, Leppäniemi, Ari, Litvin, Andrey, Peitzman, Andrew, Shelat, Vishal, Sugrue, Michael, Tolonen, Matti, Rizoli, Sandro, Sall, Ibrahima, Beka, Solomon, Di Carlo, Isidoro, Ten Broek, Richard, Mircea, Chirika, Tebala, Giovanni, Pisano, Michele, van Goor, Harry, Maier, Ronald, Jeekel, Hans, Civil, Ian, Hecker, Andreas, Tan, Edward, Soreide, Kjetil, Lee, Matthew, Wani, Imtiaz, Bonavina, Luigi, Malangoni, Mark, Koike, Kaoru, Velmahos, George, Fraga, Gustavo, Fette, Andreas, deAngelis, Nicola, Balogh, Zsolt, Scalea, Thomas, Sganga, Gabriele, Kelly, Michael, Khan, Jim, Stahel, Philip, Moore, Ernest, and Galante, Joseph
- Subjects
Bowel ischemia ,Guidelines ,Mesenteric arterial occlusion ,Mesenteric artery stenting ,Mesenteric ischemia ,Recommendations ,World Society of Emergency Surgery ,Humans ,Mesenteric Ischemia ,Mesenteric Vascular Occlusion ,Endovascular Procedures ,Ischemia ,Intestines - Abstract
Acute mesenteric ischemia (AMI) is a group of diseases characterized by an interruption of the blood supply to varying portions of the intestine, leading to ischemia and secondary inflammatory changes. If untreated, this process may progress to life-threatening intestinal necrosis. The incidence is low, estimated at 0.09-0.2% of all acute surgical admissions, but increases with age. Although the entity is an uncommon cause of abdominal pain, diligence is required because if untreated, mortality remains in the range of 50%. Early diagnosis and timely surgical intervention are the cornerstones of modern treatment to reduce the high mortality associated with this entity. The advent of endovascular approaches in parallel with modern imaging techniques is evolving and provides new treatment options. Lastly, a focused multidisciplinary approach based on early diagnosis and individualized treatment is essential. Thus, we believe that updated guidelines from World Society of Emergency Surgery are warranted, in order to provide the most recent and practical recommendations for diagnosis and treatment of AMI.
- Published
- 2022
44. Follow-up strategies for patients with splenic trauma managed non-operatively: the 2022 World Society of Emergency Surgery consensus document.
- Author
-
Podda, Mauro, De Simone, Belinda, Ceresoli, Marco, Virdis, Francesco, Favi, Francesco, Wiik Larsen, Johannes, Coccolini, Federico, Sartelli, Massimo, Pararas, Nikolaos, Beka, Solomon, Bonavina, Luigi, Bova, Raffaele, Pisanu, Adolfo, Abu-Zidan, Fikri, Balogh, Zsolt, Chiara, Osvaldo, Wani, Imtiaz, Stahel, Philip, Di Saverio, Salomone, Scalea, Thomas, Soreide, Kjetil, Sakakushev, Boris, Amico, Francesco, Martino, Costanza, Hecker, Andreas, deAngelis, Nicola, Chirica, Mircea, Kirkpatrick, Andrew, Pikoulis, Emmanouil, Kluger, Yoram, Bensard, Denis, Ansaloni, Luca, Fraga, Gustavo, Civil, Ian, Tebala, Giovanni, Di Carlo, Isidoro, Cui, Yunfeng, Coimbra, Raul, Agnoletti, Vanni, Sall, Ibrahima, Tan, Edward, Picetti, Edoardo, Litvin, Andrey, Damaskos, Dimitrios, Inaba, Kenji, Leung, Jeffrey, Maier, Ronald, Biffl, Walt, Leppaniemi, Ari, Moore, Ernest, Gurusamy, Kurinchi, Catena, Fausto, and Galante, Joseph
- Subjects
Consensus ,Conservative treatment ,Diagnostic imaging ,Embolization ,Follow-up ,Nonoperative management ,Spleen ,Trauma ,Abdominal Injuries ,Adult ,Child ,Consensus ,Follow-Up Studies ,Hemoglobins ,Heparin ,Low-Molecular-Weight ,Humans ,Prospective Studies ,Wounds ,Nonpenetrating - Abstract
BACKGROUND: In 2017, the World Society of Emergency Surgery published its guidelines for the management of adult and pediatric patients with splenic trauma. Several issues regarding the follow-up of patients with splenic injuries treated with NOM remained unsolved. METHODS: Using a modified Delphi method, we sought to explore ongoing areas of controversy in the NOM of splenic trauma and reach a consensus among a group of 48 international experts from five continents (Africa, Europe, Asia, Oceania, America) concerning optimal follow-up strategies in patients with splenic injuries treated with NOM. RESULTS: Consensus was reached on eleven clinical research questions and 28 recommendations with an agreement rate ≥ 80%. Mobilization after 24 h in low-grade splenic trauma patients (WSES Class I, AAST Grades I-II) was suggested, while in patients with high-grade splenic injuries (WSES Classes II-III, AAST Grades III-V), if no other contraindications to early mobilization exist, safe mobilization of the patient when three successive hemoglobins 8 h apart after the first are within 10% of each other was considered safe according to the panel. The panel suggests adult patients to be admitted to hospital for 1 day (for low-grade splenic injuries-WSES Class I, AAST Grades I-II) to 3 days (for high-grade splenic injuries-WSES Classes II-III, AAST Grades III-V), with those with high-grade injuries requiring admission to a monitored setting. In the absence of specific complications, the panel suggests DVT and VTE prophylaxis with LMWH to be started within 48-72 h from hospital admission. The panel suggests splenic artery embolization (SAE) as the first-line intervention in patients with hemodynamic stability and arterial blush on CT scan, irrespective of injury grade. Regarding patients with WSES Class II blunt splenic injuries (AAST Grade III) without contrast extravasation, a low threshold for SAE has been suggested in the presence of risk factors for NOM failure. The panel also suggested angiography and eventual SAE in all hemodynamically stable adult patients with WSES Class III injuries (AAST Grades IV-V), even in the absence of CT blush, especially when concomitant surgery that requires change of position is needed. Follow-up imaging with contrast-enhanced ultrasound/CT scan in 48-72 h post-admission of trauma in splenic injuries WSES Class II (AAST Grade III) or higher treated with NOM was considered the best strategy for timely detection of vascular complications. CONCLUSION: This consensus document could help guide future prospective studies aiming at validating the suggested strategies through the implementation of prospective trauma databases and the subsequent production of internationally endorsed guidelines on the issue.
- Published
- 2022
45. Postoperative pain management in non-traumatic emergency general surgery: WSES-GAIS-SIAARTI-AAST guidelines.
- Author
-
Coccolini, Federico, Corradi, Francesco, Sartelli, Massimo, Coimbra, Raul, Kryvoruchko, Igor, Leppaniemi, Ari, Doklestic, Krstina, Bignami, Elena, Biancofiore, Giandomenico, Bala, Miklosh, Marco, Ceresoli, Damaskos, Dimitris, Biffl, Walt, Fugazzola, Paola, Santonastaso, Domenico, Agnoletti, Vanni, Sbarbaro, Catia, Nacoti, Mirco, Hardcastle, Timothy, Mariani, Diego, De Simone, Belinda, Tolonen, Matti, Ball, Chad, Podda, Mauro, Di Carlo, Isidoro, Di Saverio, Salomone, Navsaria, Pradeep, Bonavina, Luigi, Abu-Zidan, Fikri, Soreide, Kjetil, Fraga, Gustavo, Carvalho, Vanessa, Batista, Sergio, Hecker, Andreas, Cucchetti, Alessandro, Ercolani, Giorgio, Tartaglia, Dario, Wani, Imtiaz, Kurihara, Hayato, Tan, Edward, Litvin, Andrey, Melotti, Rita, Sganga, Gabriele, Zoro, Tamara, Isirdi, Alessandro, DeAngelis, Nicola, Weber, Dieter, Hodonou, Adrien, tenBroek, Richard, Parini, Dario, Khan, Jim, Sbrana, Giovanni, Coniglio, Carlo, Giarratano, Antonino, Gratarola, Angelo, Zaghi, Claudia, Romeo, Oreste, Kelly, Michael, Forfori, Francesco, Chiarugi, Massimo, Moore, Ernest, Catena, Fausto, Malbrain, Manu, and Galante, Joseph
- Subjects
Acute ,Emergency ,Morbidity ,Pain ,Surgery ,Treatment ,Abdomen ,Analgesics ,Anesthesia ,Humans ,Pain ,Postoperative ,Perioperative Care ,United States - Abstract
BACKGROUND: Non-traumatic emergency general surgery involves a heterogeneous population that may present with several underlying diseases. Timeous emergency surgical treatment should be supplemented with high-quality perioperative care, ideally performed by multidisciplinary teams trained to identify and handle complex postoperative courses. Uncontrolled or poorly controlled acute postoperative pain may result in significant complications. While pain management after elective surgery has been standardized in perioperative pathways, the traditional perioperative treatment of patients undergoing emergency surgery is often a haphazard practice. The present recommended pain management guidelines are for pain management after non-traumatic emergency surgical intervention. It is meant to provide clinicians a list of indications to prescribe the optimal analgesics even in the absence of a multidisciplinary pain team. MATERIAL AND METHODS: An international expert panel discussed the different issues in subsequent rounds. Four international recognized scientific societies: World Society of Emergency Surgery (WSES), Global Alliance for Infection in Surgery (GAIS), Italian Society of Anesthesia, Analgesia Intensive Care (SIAARTI), and American Association for the Surgery of Trauma (AAST), endorsed the project and approved the final manuscript. CONCLUSION: Dealing with acute postoperative pain in the emergency abdominal surgery setting is complex, requires special attention, and should be multidisciplinary. Several tools are available, and their combination is mandatory whenever is possible. Analgesic approach to the various situations and conditions should be patient based and tailored according to procedure, pathology, age, response, and available expertise. A better understanding of the patho-mechanisms of postoperative pain for short- and long-term outcomes is necessary to improve prophylactic and treatment strategies.
- Published
- 2022
46. Hypothalamic pituitary adrenal and autonomic nervous system biomarkers of stress and tobacco relapse: Review of the research
- Author
-
LaFond, Madeleine, DeAngelis, Briana, and al'Absi, Mustafa
- Published
- 2024
- Full Text
- View/download PDF
47. Historical Redlining and Contemporary Violent Victimization Over the Life Course
- Author
-
Testa, Alexander, Jackson, Dylan B., DeAngelis, Reed, Heard-Garris, Nia, Semenza, Daniel C., and Johnson, Odis, Jr
- Published
- 2024
- Full Text
- View/download PDF
48. Uncertainty and psychological distress during COVID-19: What about protective factors?
- Author
-
Ben Salah, Arwa, DeAngelis, Briana N., and al'Absi, Mustafa
- Subjects
Epidemics -- Psychological aspects -- Tunisia ,Uncertainty -- Psychological aspects ,Stress (Psychology) -- Risk factors ,Psychology and mental health - Abstract
The present study examined the relationship between perceived uncertainty and depression/ anxiety symptoms during the COVID-19 pandemic and it tested the moderating roles of resilience and perceived social support in this relationship. A cross-sectional study was conducted between March 31st and May 15th, 2020, using an online, multi-language, international survey built within Qualtrics. We collected data on sociodemographic features, perceived uncertainty, perceived social support, depression and anxiety symptoms, and resilience. A moderation model was tested using model 2 of Hayes' PROCESS macro for SPSS. The study included 3786 respondents from 94 different countries, 47.7% of whom reported residence in the United States of America. Results demonstrated that higher perceived uncertainty was associated with more symptoms of depression and anxiety. Higher resilience levels and higher perceived social support were associated with fewer depression and anxiety symptoms. The moderation hypotheses were supported; the relationship between uncertainty and symptoms of depression and anxiety decreased as levels of resilience increased and as perceived social support increased. The results suggest that resilience and social support could be helpful targets to reduce the negative effects of uncertainty on depression and anxiety symptoms., Author(s): Arwa Ben Salah [sup.1] , Briana N. DeAngelis [sup.2] , Mustafa al'Absi [sup.2] Author Affiliations: (1) grid.411838.7, 0000 0004 0593 5040, Community Medicine Department, Faculty of Medicine of Monastir, [...]
- Published
- 2023
- Full Text
- View/download PDF
49. Charter School Funding: Inequity Surges in the Cities
- Author
-
University of Arkansas, School Choice Demonstration Project (SCDP), DeAngelis, Corey A., Wolf, Patrick J., Maloney, Larry D., and May, Jay F.
- Abstract
Public charter schools increasingly are part of both the national conversation about education policy and the local urban scene in America. Previous studies of public charter schools have examined their achievement effects focused on both the state and metropolitan levels, and funding disparities focused on the state levels. This report is the latest update to a series of studies of funding inequities concentrating on revenue disparities between charters and traditional public schools (TPS) where charters are most common: metropolitan areas across the country. This study answers two main research questions: Did public charter schools and TPS in major metropolitan areas receive equitable per-pupil funding during the 2017-18 school year? If not, what explains the funding disparity? This research indicates that urban charters tended to receive substantially less revenue on a per-pupil basis to serve their students than did traditional public schools in 2017-18. The authors find that charter school funding inequities are surging across major U.S. cities.
- Published
- 2020
50. Genome-wide association identifies novel ROP risk loci in a multiethnic cohort
- Author
-
Xiaohui Li, Leah A. Owen, Kent D. Taylor, Susan Ostmo, Yii-Der Ida Chen, Aaron S. Coyner, Kemal Sonmez, M. Elizabeth Hartnett, Xiuqing Guo, Eli Ipp, Kathryn Roll, Pauline Genter, R. V. Paul Chan, Margaret M. DeAngelis, Michael F. Chiang, J. Peter Campbell, Jerome I. Rotter, and on behalf of the i-ROP Consortium
- Subjects
Biology (General) ,QH301-705.5 - Abstract
Abstract We conducted a genome-wide association study (GWAS) in a multiethnic cohort of 920 at-risk infants for retinopathy of prematurity (ROP), a major cause of childhood blindness, identifying 1 locus at genome-wide significance level (p
- Published
- 2024
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.