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7. 2023 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Pediatric Life Support; Neonatal Life Support; Education, Implementation, and Teams; and First Aid Task Forces

Author

Berg, K. M., Bray, J. E., Ng, K. -C., Liley, H. G., Greif, R., Carlson, J. N., Morley, P. T., Drennan, I. R., Smyth, M., Scholefield, B. R., Weiner, G. M., Cheng, A., Djarv, T., Abelairas-Gomez, C., Acworth, J., Andersen, L. W., Atkins, D. L., Berry, D. C., Bhanji, F., Bierens, J., Couto, T. B., Borra, V., Bottiger, B. W., Bradley, R. N., Breckwoldt, J., Cassan, P., Chang, W. -T., Charlton, N. P., Chung, S. P., Considine, J., Costa-Nobre, D. T., Couper, K., Dainty, K. N., Dassanayake, V., Davis, P. G., Dawson, J. A., de Almeida, M. F., De Caen, A. R., Deakin, C. D., Dicker, B., Douma, M. J., Eastwood, K., El-Naggar, W., Fabres, J. G., Fawke, J., Fijacko, N., Finn, J. C., Flores, G. E., Foglia, E. E., Folke, F., Gilfoyle, E., Goolsby, C. A., Granfeldt, A., Guerguerian, A. -M., Guinsburg, R., Hatanaka, T., Hirsch, K. G., Holmberg, M. J., Hosono, S., Hsieh, M. -J., Hsu, C. H., Ikeyama, T., Isayama, T., Johnson, N. J., Kapadia, V. S., Kawakami, M. D., Kim, H. -S., Kleinman, M. E., Kloeck, D. A., Kudenchuk, P., Kule, A., Kurosawa, H., Lagina, A. T., Lauridsen, K. G., Lavonas, E. J., Lee, H. C., Lin, Y., Lockey, A. S., Macneil, F., Maconochie, I. K., Madar, R. J., Hansen, C. M., Masterson, S., Matsuyama, T., Mckinlay, C. J. D., Meyran, D., Monnelly, V., Nadkarni, V., Nakwa, F. L., Nation, K. J., Nehme, Z., Nemeth, M., Neumar, R. W., Nicholson, T., Nikolaou, N., Nishiyama, C., Norii, T., Nuthall, G. A., Ohshimo, S., Olasveengen, T. M., Ong, Y. -K. G., Orkin, A. M., Parr, M. J., Patocka, C., Perkins, G. D., Perlman, J. M., Rabi, Y., Raitt, J., Ramachandran, S., Ramaswamy, V. V., Raymond, T. T., Reis, A. G., Reynolds, J. C., Ristagno, G., Rodriguez-Nunez, A., Roehr, C. C., Rudiger, M., Sakamoto, T., Sandroni, Claudio, Sawyer, T. L., Schexnayder, S. M., Schmolzer, G. M., Schnaubelt, S., Semeraro, F., Singletary, E. M., Skrifvars, M. B., Smith, C. M., Soar, J., Stassen, W., Sugiura, T., Tijssen, J. A., Topjian, A. A., Trevisanuto, D., Vaillancourt, C., Wyckoff, M. H., Wyllie, J. P., Yang, C. -W., Yeung, J., Zelop, C. M., Zideman, D. A., Nolan, J. P., Barcala-Furelos, R., Beerman, S. B., Bruckner, M., Castren, M., Chong, S., Claesson, A., Dunne, C. L., Finan, E., Fukuda, T., Ganesan, S. L., Gately, C., Gois, A., Gray, S., Halamek, L. P., Hoover, A. V., Hurst, C., Josephsen, J., Kollander, L., Kamlin, C. O., Kool, M., Li, L., Mecrow, T. S., Montgomery, W., Ristau, P., Jayashree, M., Schmidt, A., Scquizzato, T. -M., Seesink, J., Sempsrott, J., Solevag, A. L., Strand, M. L., Szpilman, D., Szyld, E., Thom, O., Tobin, J. M., Trang, J., Webber, J., Webster, H. K., Wellsford, M., Sandroni C. (ORCID:0000-0002-8878-2611), Berg, K. M., Bray, J. E., Ng, K. -C., Liley, H. G., Greif, R., Carlson, J. N., Morley, P. T., Drennan, I. R., Smyth, M., Scholefield, B. R., Weiner, G. M., Cheng, A., Djarv, T., Abelairas-Gomez, C., Acworth, J., Andersen, L. W., Atkins, D. L., Berry, D. C., Bhanji, F., Bierens, J., Couto, T. B., Borra, V., Bottiger, B. W., Bradley, R. N., Breckwoldt, J., Cassan, P., Chang, W. -T., Charlton, N. P., Chung, S. P., Considine, J., Costa-Nobre, D. T., Couper, K., Dainty, K. N., Dassanayake, V., Davis, P. G., Dawson, J. A., de Almeida, M. F., De Caen, A. R., Deakin, C. D., Dicker, B., Douma, M. J., Eastwood, K., El-Naggar, W., Fabres, J. G., Fawke, J., Fijacko, N., Finn, J. C., Flores, G. E., Foglia, E. E., Folke, F., Gilfoyle, E., Goolsby, C. A., Granfeldt, A., Guerguerian, A. -M., Guinsburg, R., Hatanaka, T., Hirsch, K. G., Holmberg, M. J., Hosono, S., Hsieh, M. -J., Hsu, C. H., Ikeyama, T., Isayama, T., Johnson, N. J., Kapadia, V. S., Kawakami, M. D., Kim, H. -S., Kleinman, M. E., Kloeck, D. A., Kudenchuk, P., Kule, A., Kurosawa, H., Lagina, A. T., Lauridsen, K. G., Lavonas, E. J., Lee, H. C., Lin, Y., Lockey, A. S., Macneil, F., Maconochie, I. K., Madar, R. J., Hansen, C. M., Masterson, S., Matsuyama, T., Mckinlay, C. J. D., Meyran, D., Monnelly, V., Nadkarni, V., Nakwa, F. L., Nation, K. J., Nehme, Z., Nemeth, M., Neumar, R. W., Nicholson, T., Nikolaou, N., Nishiyama, C., Norii, T., Nuthall, G. A., Ohshimo, S., Olasveengen, T. M., Ong, Y. -K. G., Orkin, A. M., Parr, M. J., Patocka, C., Perkins, G. D., Perlman, J. M., Rabi, Y., Raitt, J., Ramachandran, S., Ramaswamy, V. V., Raymond, T. T., Reis, A. G., Reynolds, J. C., Ristagno, G., Rodriguez-Nunez, A., Roehr, C. C., Rudiger, M., Sakamoto, T., Sandroni, Claudio, Sawyer, T. L., Schexnayder, S. M., Schmolzer, G. M., Schnaubelt, S., Semeraro, F., Singletary, E. M., Skrifvars, M. B., Smith, C. M., Soar, J., Stassen, W., Sugiura, T., Tijssen, J. A., Topjian, A. A., Trevisanuto, D., Vaillancourt, C., Wyckoff, M. H., Wyllie, J. P., Yang, C. -W., Yeung, J., Zelop, C. M., Zideman, D. A., Nolan, J. P., Barcala-Furelos, R., Beerman, S. B., Bruckner, M., Castren, M., Chong, S., Claesson, A., Dunne, C. L., Finan, E., Fukuda, T., Ganesan, S. L., Gately, C., Gois, A., Gray, S., Halamek, L. P., Hoover, A. V., Hurst, C., Josephsen, J., Kollander, L., Kamlin, C. O., Kool, M., Li, L., Mecrow, T. S., Montgomery, W., Ristau, P., Jayashree, M., Schmidt, A., Scquizzato, T. -M., Seesink, J., Sempsrott, J., Solevag, A. L., Strand, M. L., Szpilman, D., Szyld, E., Thom, O., Tobin, J. M., Trang, J., Webber, J., Webster, H. K., Wellsford, M., and Sandroni C. (ORCID:0000-0002-8878-2611)

Abstract

The International Liaison Committee on Resuscitation engages in a continuous review of new, peer-reviewed, published cardiopulmonary resuscitation and first aid science. Draft Consensus on Science With Treatment Recommendations are posted online throughout the year, and this annual summary provides more concise versions of the final Consensus on Science With Treatment Recommendations from all task forces for the year. Topics addressed by systematic reviews this year include resuscitation of cardiac arrest from drowning, extracorporeal cardiopulmonary resuscitation for adults and children, calcium during cardiac arrest, double sequential defibrillation, neuroprognostication after cardiac arrest for adults and children, maintaining normal temperature after preterm birth, heart rate monitoring methods for diagnostics in neonates, detection of exhaled carbon dioxide in neonates, family presence during resuscitation of adults, and a stepwise approach to resuscitation skills training. Members from 6 International Liaison Committee on Resuscitation task forces have assessed, discussed, and debated the quality of the evidence, using Grading of Recommendations Assessment, Development, and Evaluation criteria, and their statements include consensus treatment recommendations. Insights into the deliberations of the task forces are provided in the Justification and Evidence-to-Decision Framework Highlights sections. In addition, the task forces list priority knowledge gaps for further research. Additional topics are addressed with scoping reviews and evidence updates.

Published
2023

13. 2022 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science with Treatment Recommendations: Summary from the Basic Life Support; Advanced Life Support; Pediatric Life Support; Neonatal Life Support; Education, Implementation, and Teams; And First Aid Task Forces

Author

Wyckoff, M. H., Greif, R., Morley, P. T., Ng, K. -C., Olasveengen, T. M., Singletary, E. M., Soar, J., Cheng, A., Drennan, I. R., Liley, H. G., Scholefield, B. R., Smyth, M. A., Welsford, M., Zideman, D. A., Acworth, J., Aickin, R., Andersen, L. W., Atkins, D., Berry, D. C., Bhanji, F., Bierens, J., Borra, V., Bottiger, B. W., Bradley, R. N., Bray, J. E., Breckwoldt, J., Callaway, C. W., Carlson, J. N., Cassan, P., Castren, M., Chang, W. -T., Charlton, N. P., Chung, S. P., Considine, J., Costa-Nobre, D. T., Couper, K., Couto, T. B., Dainty, K. N., Davis, P. G., De Almeida, M. F., De Caen, A. R., Deakin, C. D., Djarv, T., Donnino, M. W., Douma, M. J., Duff, J. P., Dunne, C. L., Eastwood, K., El-Naggar, W., Fabres, J. G., Fawke, J., Finn, J., Foglia, E. E., Folke, F., Gilfoyle, E., Goolsby, C. A., Granfeldt, A., Guerguerian, A. -M., Guinsburg, R., Hirsch, K. G., Holmberg, M. J., Hosono, S., Hsieh, M. -J., Hsu, C. H., Ikeyama, T., Isayama, T., Johnson, N. J., Kapadia, V. S., Kawakami, M. D., Kim, H. -S., Kleinman, M., Kloeck, D. A., Kudenchuk, P. J., Lagina, A. T., Lauridsen, K. G., Lavonas, E. J., Lee, H. C., Lin, Y. (., Lockey, A. S., Maconochie, I. K., Madar, R. J., Malta Hansen, C., Masterson, S., Matsuyama, T., Mckinlay, C. J. D., Meyran, D., Morgan, P., Morrison, L. J., Nadkarni, V., Nakwa, F. L., Nation, K. J., Nehme, Z., Nemeth, M., Neumar, R. W., Nicholson, T., Nikolaou, N., Nishiyama, C., Norii, T., Nuthall, G. A., O'Neill, B. J., Ong, Y. -K. G., Orkin, A. M., Paiva, E. F., Parr, M. J., Patocka, C., Pellegrino, J. L., Perkins, G. D., Perlman, J. M., Rabi, Y., Reis, A. G., Reynolds, J. C., Ristagno, G., Rodriguez-Nunez, A., Roehr, C. C., Rudiger, M., Sakamoto, T., Sandroni, Claudio, Sawyer, T. L., Schexnayder, S. M., Schmolzer, G. M., Schnaubelt, S., Semeraro, F., Skrifvars, M. B., Smith, C. M., Sugiura, T., Tijssen, J. A., Trevisanuto, D., Van De Voorde, P., Wang, T. -L., Weiner, G. M., Wyllie, J. P., Yang, C. -W., Yeung, J., Nolan, J. P., Berg, K. M., Burdick, M. C., Cartledge, S., Dawson, J. A., Elgohary, M. M., Ersdal, H. L., Finan, E., Flaatten, H. I., Flores, G. E., Fuerch, J., Garg, R., Gately, C., Goh, M., Halamek, L. P., Handley, A. J., Hatanaka, T., Hoover, A., Issa, M., Johnson, S., Kamlin, C. O., Ko, Y. -C., Kule, A., Leone, T. A., Mackenzie, E., Macneil, F., Montgomery, W., O'Dochartaigh, D., Ohshimo, S., Palazzo, F. S., Picard, C., Quek, B. H., Raitt, J., Ramaswamy, V. V., Scapigliati, Andrea, Shah, B. A., Stewart, C., Strand, M. L., Szyld, E., Thio, M., Topjian, A. A., Udaeta, E., Vaillancourt, C., Wetsch, W. A., Wigginton, J., Yamada, N. K., Yao, S., Zace, D., Zelop, C. M., Sandroni C. (ORCID:0000-0002-8878-2611), Scapigliati A. (ORCID:0000-0002-4044-2343), Wyckoff, M. H., Greif, R., Morley, P. T., Ng, K. -C., Olasveengen, T. M., Singletary, E. M., Soar, J., Cheng, A., Drennan, I. R., Liley, H. G., Scholefield, B. R., Smyth, M. A., Welsford, M., Zideman, D. A., Acworth, J., Aickin, R., Andersen, L. W., Atkins, D., Berry, D. C., Bhanji, F., Bierens, J., Borra, V., Bottiger, B. W., Bradley, R. N., Bray, J. E., Breckwoldt, J., Callaway, C. W., Carlson, J. N., Cassan, P., Castren, M., Chang, W. -T., Charlton, N. P., Chung, S. P., Considine, J., Costa-Nobre, D. T., Couper, K., Couto, T. B., Dainty, K. N., Davis, P. G., De Almeida, M. F., De Caen, A. R., Deakin, C. D., Djarv, T., Donnino, M. W., Douma, M. J., Duff, J. P., Dunne, C. L., Eastwood, K., El-Naggar, W., Fabres, J. G., Fawke, J., Finn, J., Foglia, E. E., Folke, F., Gilfoyle, E., Goolsby, C. A., Granfeldt, A., Guerguerian, A. -M., Guinsburg, R., Hirsch, K. G., Holmberg, M. J., Hosono, S., Hsieh, M. -J., Hsu, C. H., Ikeyama, T., Isayama, T., Johnson, N. J., Kapadia, V. S., Kawakami, M. D., Kim, H. -S., Kleinman, M., Kloeck, D. A., Kudenchuk, P. J., Lagina, A. T., Lauridsen, K. G., Lavonas, E. J., Lee, H. C., Lin, Y. (., Lockey, A. S., Maconochie, I. K., Madar, R. J., Malta Hansen, C., Masterson, S., Matsuyama, T., Mckinlay, C. J. D., Meyran, D., Morgan, P., Morrison, L. J., Nadkarni, V., Nakwa, F. L., Nation, K. J., Nehme, Z., Nemeth, M., Neumar, R. W., Nicholson, T., Nikolaou, N., Nishiyama, C., Norii, T., Nuthall, G. A., O'Neill, B. J., Ong, Y. -K. G., Orkin, A. M., Paiva, E. F., Parr, M. J., Patocka, C., Pellegrino, J. L., Perkins, G. D., Perlman, J. M., Rabi, Y., Reis, A. G., Reynolds, J. C., Ristagno, G., Rodriguez-Nunez, A., Roehr, C. C., Rudiger, M., Sakamoto, T., Sandroni, Claudio, Sawyer, T. L., Schexnayder, S. M., Schmolzer, G. M., Schnaubelt, S., Semeraro, F., Skrifvars, M. B., Smith, C. M., Sugiura, T., Tijssen, J. A., Trevisanuto, D., Van De Voorde, P., Wang, T. -L., Weiner, G. M., Wyllie, J. P., Yang, C. -W., Yeung, J., Nolan, J. P., Berg, K. M., Burdick, M. C., Cartledge, S., Dawson, J. A., Elgohary, M. M., Ersdal, H. L., Finan, E., Flaatten, H. I., Flores, G. E., Fuerch, J., Garg, R., Gately, C., Goh, M., Halamek, L. P., Handley, A. J., Hatanaka, T., Hoover, A., Issa, M., Johnson, S., Kamlin, C. O., Ko, Y. -C., Kule, A., Leone, T. A., Mackenzie, E., Macneil, F., Montgomery, W., O'Dochartaigh, D., Ohshimo, S., Palazzo, F. S., Picard, C., Quek, B. H., Raitt, J., Ramaswamy, V. V., Scapigliati, Andrea, Shah, B. A., Stewart, C., Strand, M. L., Szyld, E., Thio, M., Topjian, A. A., Udaeta, E., Vaillancourt, C., Wetsch, W. A., Wigginton, J., Yamada, N. K., Yao, S., Zace, D., Zelop, C. M., Sandroni C. (ORCID:0000-0002-8878-2611), and Scapigliati A. (ORCID:0000-0002-4044-2343)

Abstract

This is the sixth annual summary of the International Liaison Committee on Resuscitation International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations. This summary addresses the most recently published resuscitation evidence reviewed by International Liaison Committee on Resuscitation Task Force science experts. Topics covered by systematic reviews include cardiopulmonary resuscitation during transport; approach to resuscitation after drowning; passive ventilation; minimizing pauses during cardiopulmonary resuscitation; temperature management after cardiac arrest; use of diagnostic point-of-care ultrasound during cardiac arrest; use of vasopressin and corticosteroids during cardiac arrest; coronary angiography after cardiac arrest; public-access defibrillation devices for children; pediatric early warning systems; maintaining normal temperature immediately after birth; suctioning of amniotic fluid at birth; tactile stimulation for resuscitation immediately after birth; use of continuous positive airway pressure for respiratory distress at term birth; respiratory and heart rate monitoring in the delivery room; supraglottic airway use in neonates; prearrest prediction of in-hospital cardiac arrest mortality; basic life support training for likely rescuers of high-risk populations; effect of resuscitation team training; blended learning for life support training; training and recertification for resuscitation instructors; and recovery position for maintenance of breathing and prevention of cardiac arrest. Members from 6 task forces have assessed, discussed, and debated the quality of the evidence using Grading of Recommendations Assessment, Development, and Evaluation criteria and generated consensus treatment recommendations. Insights into the deliberations of the task forces are provided in the Justification and Evidence-to-Decision Framework Highlights sections, and priority knowledge gaps for futu

Published
2022

15. POS0691 EMULATING A TARGET TRIAL OF ADALIMUMAB VERSUS TOFACITINIB IN PATIENTS WITH RHEUMATOID ARTHRITIS: A COMPARATIVE EFFECTIVENESS ANALYSIS USING THE OPAL REAL-WORLD DATASET

Author

Deakin, C., primary, De Stavola, B., additional, Littlejohn, G., additional, Griffiths, H., additional, Ciciriello, S., additional, Youssef, P., additional, Mathers, D., additional, Bird, P., additional, Smith, T., additional, Osullivan, C., additional, Freeman, T., additional, Segelov, D., additional, Hoffman, D., additional, and Seaman, S., additional

Published
2022
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17. Corrigendum to 'European Resuscitation Council Guidelines 2021: Executive summary' [Resuscitation (2021) 1–60] (Resuscitation (2021) 161 (1–60), (S0300957221000551), (10.1016/j.resuscitation.2021.02.003))

Author

Perkins, Gavin D., Gräsner, Jan-Thortsen, Semeraro, Federico, Olasveengen, Theresa, Soar, Jasmeet, Lott, Carsten, Voorde, Patrick, Madar, John, Zideman, David, Mentzelopoulos, Spyridon, Bossaert, Leo, Greif, Robert, Monsieurs, Koen, Svavarsdóttir, Hildigunnur, Nolan, Jerry P., Ainsworth, S., Deakin, C. D., Lippert, F., Sandroni, C., Akin, S., Delchef, J., Lockey, A. S., Sari, F., Alfonzo, A., Dirks, B., Lott, C., Scapigliati, A., Andres, J., Djakow, J., Lulic, I., Schilder, S., Attard Montalto, S., Djarv, T., Maas, M., Schlieber, J., Barelli, A., Druwe, P., Maconochie, I., Schnaubelt, S., Baubin, M., Eldin, G., Madar, J., Semeraro, F., Behringer, W., Ersdal, H., Martinez-Mejias, A., Shammet, S., Bein, B., Friberg, H., Masterson, S., Singletary, E. M., Biarent, D., Genbrugge, C., Mentzelopoulos, S. D., Skåre, C., Bingham, R., Georgiou, M., Meyran, D., Skrifvars, M. B., Blom, M., Goemans, E., Monsieurs, K. G., Smyth, M., Boccuzzi, A., González-Salvado, V., Morley, C., Soar, J., Borra, V., Gradisek, P., Moulaert, V. R. M., Svavarsdóttir, H., Bossaert, L., Gräsner, J. T., Mpotos, N., Szczapa, T., Böttiger, B. W., Greif, R., Nikolaou, N., Taccone, F., Breckwoldt, J., Handley, A. J., Nolan, J. P., Tageldin Mustafa, M., Brissaud, O., Hassager, C., Olasveengen, T. M., Te Pas, A., Burkart, R., Haywood, K., Oliver, E., Karl-Christian Thies, Cariou, A., Heltne, J. K., Paal, P., Tjelmeland, I. B. M., Carli, P., Hendrickx, D., Pellis, T., Trevisanuto, D., Carmona, F., Herlitz, J., Perkins, G. D., Truhlár, A., Cassan, P., Hinkelbein, J., Pflanzl-Knizacek, L., Trummer, G., Castren, M., Hoffmann, F., Pitches, K., Turner, N. M., Christophides, T., Hunyadi Anticevic, S., Poole, K., Urlesberger, B., Cimpoesu, C. D., Johannesdottir, G. B., Raffay, V., Vaahersalo, J., Clarens, C., Khalifa, G., Renier, W., Voorde, P., Conaghan, P., Klaassen, B., Ristagno, G., Grootven, H., Couper, K., Koppl, J., Roehr, C. C., Wilkinson, D., Cronberg, T., Kreimeier, U., Rosell-Ortiz, F., Wnent, J., Buck, E., Kuzovlev, A., Rüdiger, M., Wyllie, J. P., Lucas, N., Lauritsen, T., Safri, A., Yeung, J., Roovere, A., Lilja, G., Sanchez Santos, L., Zideman, D. A., Radiology and Nuclear Medicine, AMS - Rehabilitation & Development, AMS - Sports, Amsterdam Gastroenterology Endocrinology Metabolism, Cardiology, ACS - Heart failure & arrhythmias, and APH - Health Behaviors & Chronic Diseases

Abstract

The authors regret that the list of the ERC 2021 Guidelines Collaborators which were included in Appendix A was incomplete. The complete list of collaborators is provided below: [Table presented] The authors would like to apologise for any inconvenience caused.

Published
2021

19. Histological heterogeneity in a large clinical cohort of juvenile idiopathic inflammatory myopathy: analysis by myositis autoantibody and pathological features

Author

Yasin, S. A., Schutz, P. W., Deakin, C. T., Sag, E., Varsani, H., Simou, S., Marshall, L. R., Tansley, S. L., McHugh, N. J., Holton, J. L., Wedderburn, L. R., and Jacques, T. S.

Subjects
Male, dermatomyositis, Myositis, principal component analysis, Original Articles, JDM score tool, Autoantigens, immune mediated necrotizing myopathy, polymyositis, Cohort Studies, anti‐SRP, Phenotype, Child, Preschool, Humans, Original Article, Female, Child, Autoantibodies
Abstract

Aim Juvenile idiopathic inflammatory myopathies have been recently reclassified into clinico‐serological subgroups. Myopathological correlates of the subgroups are incompletely understood. Methods We studied muscle biopsies from 101 children with clinically and serologically defined juvenile idiopathic inflammatory myopathies from the UK JDM Cohort and Biomarker Study by applying the international JDM score tool, myopathological review and C5b‐9 complement analysis. Results Autoantibody data were available for 90/101 cases with 18/90 cases positive for anti‐TIF1γ, 15/90 anti‐NXP2, 11/90 anti‐MDA5, 5/90 anti‐Mi2 and 6/90 anti‐PmScl. JDM biopsy severity scores were consistently low in the anti‐MDA5 group, high in the anti‐Mi2 group, and widely distributed in the other groups. Biopsies were classified histologically as perifascicular atrophy (22/101), macrophage‐rich necrosis (6/101), scattered necrosis (2/101), clustered necrosis (2/101), inflammatory fibre invasion (2/101), chronic myopathic change (1/101), diffuse endomysial macrophage infiltrates (40/101) and minimal change (24/101). MDA5 cases segregated with the minimal change group and showed no capillary C5b‐9‐deposition. The Mi2 group displayed high severity scores and a tendency towards sarcolemmal complement deposition. NXP2 and TIF1γ groups showed a variety of pathologies with a high proportion of diffuse endomysial macrophage infiltrates and a high proportion of capillary C5b‐9 deposition. Conclusion We have shown that juvenile idiopathic inflammatory myopathies have a spectrum of histopathological phenotypes and show distinct complement attack complex deposition patterns. Both correlate in some cases with the serological subtypes. Most cases do not show typical histological features associated with dermatomyositis (e.g. perifascicular atrophy). In contrast, more than half show relatively mild histopathological changes.

Published
2019

20. Sub-phenotyping of juvenile dermatomyositis: O19

Author

Deakin, C. T., Yasin, S. A., Arnold, K., Tansley, S. L., Betteridge, Z. E., McHugh, N. J., Holton, J. L., Jacques, T. S., Pilkington, C., De Iorio, M., and Wedderburn, L. R.

Published
2015

21. Adult advanced life support: European Resuscitation Council Guidelines 2021

Author

Soar, J., Bottiger, B. W., Carli, P., Couper, K., Deakin, C. D., Djarv, T., Lott, C., Olasveengen, T., Paal, P., Pellis, T., Perkins, G. D., Sandroni, Claudio, and Nolan, J. P.

Subjects
Treatment Recommendations, Extracorporeal CPR (eCPR), Mechanical chest compression devices, Settore MED/41 - ANESTESIOLOGIA, Premonitory signs, Airway managment
Published
2021

22. 2021 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Neonatal Life Support; Education, Implementation, and Teams; First Aid Task Forces; and the COVID-19 Working Group

Author

Wyckoff, M. H., Singletary, E. M., Soar, J., Olasveengen, T. M., Greif, R., Liley, H. G., Zideman, D., Bhanji, F., Andersen, L. W., Avis, S. R., Aziz, K., Bendall, J. C., Berry, D. C., Borra, V., Bottiger, B. W., Bradley, R., Bray, J. E., Breckwoldt, J., Carlson, J. N., Cassan, P., Castren, M., Chang, W. -T., Charlton, N. P., Cheng, A., Chung, S. P., Considine, J., Costa-Nobre, D. T., Couper, K., Dainty, K. N., Davis, P. G., de Almeida, M. F., de Caen, A. R., de Paiva, E. F., Deakin, C. D., Djarv, T., Douma, M. J., Drennan, I. R., Duff, J. P., Eastwood, K. J., El-Naggar, W., Epstein, J. L., Escalante, R., Fabres, J. G., Fawke, J., Finn, J. C., Foglia, E. E., Folke, F., Freeman, K., Gilfoyle, E., Goolsby, C. A., Grove, A., Guinsburg, R., Hatanaka, T., Hazinski, M. F., Heriot, G. S., Hirsch, K. G., Holmberg, M. J., Hosono, S., Hsieh, M. -J., Hung, K. K. C., Hsu, C. H., Ikeyama, T., Isayama, T., Kapadia, V. S., Kawakami, M. D., Kim, H. -S., Kloeck, D. A., Kudenchuk, P. J., Lagina, A. T., Lauridsen, K. G., Lavonas, E. J., Lockey, A. S., Malta Hansen, C., Markenson, D., Matsuyama, T., Mckinlay, C. J. D., Mehrabian, A., Merchant, R. M., Meyran, D., Morley, P. T., Morrison, L. J., Nation, K. J., Nemeth, M., Neumar, R. W., Nicholson, T., Niermeyer, S., Nikolaou, N., Nishiyama, C., O'Neil, B. J., Orkin, A. M., Osemeke, O., Parr, M. J., Patocka, C., Pellegrino, J. L., Perkins, G. D., Perlman, J. M., Rabi, Y., Reynolds, J. C., Ristagno, G., Roehr, C. C., Sakamoto, T., Sandroni, Claudio, Sawyer, T., Schmolzer, G. M., Schnaubelt, S., Semeraro, F., Skrifvars, M. B., Smith, C. M., Smyth, M. A., Soll, R. F., Sugiura, T., Taylor-Phillips, S., Trevisanuto, D., Vaillancourt, C., Wang, T. -L., Weiner, G. M., Welsford, M., Wigginton, J., Wyllie, J. P., Yeung, J., Nolan, J. P., Berg, K. M., Abelairas-Gomez, C., Barcala-Furelos, R., Beerman, S. B., Bierens, J., Cacciola, Sofia, Cellini, J., Claesson, A., Court, R., D'Arrigo, Sonia, De Brier, N., Dunne, C. L., Elsenga, H. E., Johnson, S., Kleven, G., Maconochie, I., Mecrow, T., Morgan, P., Otto, Q., Palmieri, T. L., Parnia, S., Pawar, R., Pereira, J., Rudd, S., Scapigliati, Andrea, Schmidt, A., Seesink, J., Sempsrott, J. R., Szpilman, D., Warner, D. S., Webber, J. B., West, R. L., Sandroni C. (ORCID:0000-0002-8878-2611), Cacciola S., D'Arrigo S. (ORCID:0000-0001-6740-3195), Scapigliati A. (ORCID:0000-0002-4044-2343), Wyckoff, M. H., Singletary, E. M., Soar, J., Olasveengen, T. M., Greif, R., Liley, H. G., Zideman, D., Bhanji, F., Andersen, L. W., Avis, S. R., Aziz, K., Bendall, J. C., Berry, D. C., Borra, V., Bottiger, B. W., Bradley, R., Bray, J. E., Breckwoldt, J., Carlson, J. N., Cassan, P., Castren, M., Chang, W. -T., Charlton, N. P., Cheng, A., Chung, S. P., Considine, J., Costa-Nobre, D. T., Couper, K., Dainty, K. N., Davis, P. G., de Almeida, M. F., de Caen, A. R., de Paiva, E. F., Deakin, C. D., Djarv, T., Douma, M. J., Drennan, I. R., Duff, J. P., Eastwood, K. J., El-Naggar, W., Epstein, J. L., Escalante, R., Fabres, J. G., Fawke, J., Finn, J. C., Foglia, E. E., Folke, F., Freeman, K., Gilfoyle, E., Goolsby, C. A., Grove, A., Guinsburg, R., Hatanaka, T., Hazinski, M. F., Heriot, G. S., Hirsch, K. G., Holmberg, M. J., Hosono, S., Hsieh, M. -J., Hung, K. K. C., Hsu, C. H., Ikeyama, T., Isayama, T., Kapadia, V. S., Kawakami, M. D., Kim, H. -S., Kloeck, D. A., Kudenchuk, P. J., Lagina, A. T., Lauridsen, K. G., Lavonas, E. J., Lockey, A. S., Malta Hansen, C., Markenson, D., Matsuyama, T., Mckinlay, C. J. D., Mehrabian, A., Merchant, R. M., Meyran, D., Morley, P. T., Morrison, L. J., Nation, K. J., Nemeth, M., Neumar, R. W., Nicholson, T., Niermeyer, S., Nikolaou, N., Nishiyama, C., O'Neil, B. J., Orkin, A. M., Osemeke, O., Parr, M. J., Patocka, C., Pellegrino, J. L., Perkins, G. D., Perlman, J. M., Rabi, Y., Reynolds, J. C., Ristagno, G., Roehr, C. C., Sakamoto, T., Sandroni, Claudio, Sawyer, T., Schmolzer, G. M., Schnaubelt, S., Semeraro, F., Skrifvars, M. B., Smith, C. M., Smyth, M. A., Soll, R. F., Sugiura, T., Taylor-Phillips, S., Trevisanuto, D., Vaillancourt, C., Wang, T. -L., Weiner, G. M., Welsford, M., Wigginton, J., Wyllie, J. P., Yeung, J., Nolan, J. P., Berg, K. M., Abelairas-Gomez, C., Barcala-Furelos, R., Beerman, S. B., Bierens, J., Cacciola, Sofia, Cellini, J., Claesson, A., Court, R., D'Arrigo, Sonia, De Brier, N., Dunne, C. L., Elsenga, H. E., Johnson, S., Kleven, G., Maconochie, I., Mecrow, T., Morgan, P., Otto, Q., Palmieri, T. L., Parnia, S., Pawar, R., Pereira, J., Rudd, S., Scapigliati, Andrea, Schmidt, A., Seesink, J., Sempsrott, J. R., Szpilman, D., Warner, D. S., Webber, J. B., West, R. L., Sandroni C. (ORCID:0000-0002-8878-2611), Cacciola S., D'Arrigo S. (ORCID:0000-0001-6740-3195), and Scapigliati A. (ORCID:0000-0002-4044-2343)

Abstract

The International Liaison Committee on Resuscitation initiated a continuous review of new, peer-reviewed published cardiopulmonary resuscitation science. This is the fifth annual summary of the International Liaison Committee on Resuscitation International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations; a more comprehensive review was done in 2020. This latest summary addresses the most recently published resuscitation evidence reviewed by International Liaison Committee on Resuscitation task force science experts. Topics covered by systematic reviews in this summary include resuscitation topics of video-based dispatch systems; head-up cardiopulmonary resuscitation; early coronary angiography after return of spontaneous circulation; cardiopulmonary resuscitation in the prone patient; cord management at birth for preterm and term infants; devices for administering positive-pressure ventilation at birth; family presence during neonatal resuscitation; self-directed, digitally based basic life support education and training in adults and children; coronavirus disease 2019 infection risk to rescuers from patients in cardiac arrest; and first aid topics, including cooling with water for thermal burns, oral rehydration for exertional dehydration, pediatric tourniquet use, and methods of tick removal. Members from 6 International Liaison Committee on Resuscitation task forces have assessed, discussed, and debated the quality of the evidence, according to the Grading of Recommendations Assessment, Development, and Evaluation criteria, and their statements include consensus treatment recommendations or good practice statements. Insights into the deliberations of the task forces are provided in Justification and Evidence-to-Decision Framework Highlights sections. In addition, the task forces listed priority knowledge gaps for further research.

Published
2021

23. European Resuscitation Council Guidelines 2021: Adult advanced life support

Author

Soar, J., Bottiger, B. W., Carli, P., Couper, K., Deakin, C. D., Djarv, T., Lott, C., Olasveengen, T., Paal, P., Pellis, T., Perkins, G. D., Sandroni, Claudio, Nolan, J. P., Sandroni C. (ORCID:0000-0002-8878-2611), Soar, J., Bottiger, B. W., Carli, P., Couper, K., Deakin, C. D., Djarv, T., Lott, C., Olasveengen, T., Paal, P., Pellis, T., Perkins, G. D., Sandroni, Claudio, Nolan, J. P., and Sandroni C. (ORCID:0000-0002-8878-2611)

Abstract

These European Resuscitation Council Advanced Life Support guidelines, are based on the 2020 International Consensus on Cardiopulmonary Resuscitation Science with Treatment Recommendations. This section provides guidelines on the prevention of and ALS treatments for both in-hospital cardiac arrest and out-of-hospital cardiac arrest.

Published
2021

25. Encapsulation of methylammonium lead bromide perovskite in nanoporous GaN

Author

Lim, KTP, Deakin, C, Ding, B, Bai, X, Griffin, P, Zhu, T, Oliver, RA, Credgington, D, Lim, KTP [0000-0002-9318-6232], Deakin, C [0000-0003-3138-3676], Griffin, P [0000-0003-4239-9227], Zhu, T [0000-0002-9481-8203], Oliver, RA [0000-0003-0029-3993], Credgington, D [0000-0003-4246-2118], and Apollo - University of Cambridge Repository

Subjects
lcsh:Biotechnology, lcsh:TP248.13-248.65, 4018 Nanotechnology, 5104 Condensed Matter Physics, 51 Physical Sciences, lcsh:Physics, lcsh:QC1-999, 4016 Materials Engineering, 40 Engineering
Abstract

© 2019 Author(s). Halide perovskites hold exceptional promise as cheap, low temperature solution-processed optoelectronic materials. Yet they are hindered by poor structural and chemical stability, rapidly degrading when exposed to moisture or air. We demonstrate a solution-phase method for infiltrating methylammonium lead bromide perovskite (CH 3 NH 3 PbBr 3 , or MAPbBr 3 ) into nanoporous GaN which preserved the green photoluminescence of the perovskite after up to 1 year of storage under ambient conditions. Besides a protective effect, confinement within the porous GaN matrix also resulted in a blueshift of the perovskite emission with decreasing pore size, suggesting an additional templating effect of the pores on the size of the perovskite crystals within. We anticipate that our method may be generalised to related perovskite materials, offering a route to producing composites of interest for use in optoelectronic devices for various applications.

Published
2019
Full Text
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27. POS1461-HPR THE DEVELOPMENT OF A NOVEL EPRO DELIVERY SYSTEM TO MEASURE PATIENT QUALITY OF LIFE IN ROUTINE CLINICAL CARE: AN ANALYSIS OF 5 YEARS OF EXPERIENCE

Author

Tymms, K., primary, Smith, T., additional, Deakin, C., additional, Freeman, T., additional, Hoffman, D., additional, Segelov, D., additional, Griffiths, H., additional, Ciciriello, S., additional, Youssef, P., additional, Mathers, D., additional, Osullivan, C., additional, and Littlejohn, G., additional

Published
2021
Full Text
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33. Adult Advanced Life Support: 2020 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations

Author

Berg, K. M., Soar, J., Andersen, L. W., Bottiger, B. W., Cacciola, S., Callaway, C. W., Couper, K., Cronberg, T., D'Arrigo, S., Deakin, C. D., Donnino, M. W., Drennan, I. R., Granfeldt, A., Hoedemaekers, C. W. E., Holmberg, M. J., Hsu, C. H., Kamps, M., Musiol, S., Nation, K. J., Neumar, R. W., Nicholson, T., O'Neil, B. J., Otto, Q., de Paiva, E. F., Parr, M. J. A., Reynolds, J. C., Sandroni, C., Scholefield, B. R., Skrifvars, M. B., Wang, T. -L., Wetsch, W. A., Yeung, J., Morley, P. T., Morrison, L. J., Welsford, M., Hazinski, M. F., Nolan, J. P., Cacciola S., D'Arrigo S. (ORCID:0000-0001-6740-3195), Sandroni C. (ORCID:0000-0002-8878-2611), Berg, K. M., Soar, J., Andersen, L. W., Bottiger, B. W., Cacciola, S., Callaway, C. W., Couper, K., Cronberg, T., D'Arrigo, S., Deakin, C. D., Donnino, M. W., Drennan, I. R., Granfeldt, A., Hoedemaekers, C. W. E., Holmberg, M. J., Hsu, C. H., Kamps, M., Musiol, S., Nation, K. J., Neumar, R. W., Nicholson, T., O'Neil, B. J., Otto, Q., de Paiva, E. F., Parr, M. J. A., Reynolds, J. C., Sandroni, C., Scholefield, B. R., Skrifvars, M. B., Wang, T. -L., Wetsch, W. A., Yeung, J., Morley, P. T., Morrison, L. J., Welsford, M., Hazinski, M. F., Nolan, J. P., Cacciola S., D'Arrigo S. (ORCID:0000-0001-6740-3195), and Sandroni C. (ORCID:0000-0002-8878-2611)

Abstract

This 2020 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations for advanced life support includes updates on multiple advanced life support topics addressed with 3 different types of reviews. Topics were prioritized on the basis of both recent interest within the resuscitation community and the amount of new evidence available since any previous review. Systematic reviews addressed higher-priority topics, and included double-sequential defibrillation, intravenous versus intraosseous route for drug administration during cardiac arrest, point-of-care echocardiography for intra-arrest prognostication, cardiac arrest caused by pulmonary embolism, postresuscitation oxygenation and ventilation, prophylactic antibiotics after resuscitation, postresuscitation seizure prophylaxis and treatment, and neuroprognostication. New or updated treatment recommendations on these topics are presented. Scoping reviews were conducted for anticipatory charging and monitoring of physiological parameters during cardiopulmonary resuscitation. Topics for which systematic reviews and new Consensuses on Science With Treatment Recommendations were completed since 2015 are also summarized here. All remaining topics reviewed were addressed with evidence updates to identify any new evidence and to help determine which topics should be the highest priority for systematic reviews in the next 1 to 2 years.

Published
2020

41. Cardiac Arrest and Cardiopulmonary Resuscitation Outcome Reports: Update of the Utstein Resuscitation Registry Template for In-Hospital Cardiac Arrest: A Consensus Report From a Task Force of the International Liaison Committee on Resuscitation (American Heart Association, European Resuscitation Council, Australian and New Zealand Council on Resuscitation, Heart and Stroke Foundation of Canada, InterAmerican Heart Foundation, Resuscitation Council of Southern Africa, Resuscitation Council of Asia)

Author

Nolan, J. P., Berg, R. A., Andersen, L. W., Bhanji, F., Chan, P. S., Donnino, M. W., Lim, S. H., M. H. -M., Ma, Nadkarni, V. M., Starks, M. A., Perkins, G. D., Morley, P. T., Soar, J., Aickin, R., Atkins, D. L., Berg, K. M., Bingham, R., Bottiger, B. W., Brooks, S. C., Callaway, C. W., Castren, M., Chung, S. P., Considine, J., Couto, T. B., de Caen, A. R., Deakin, C. D., Drennan, I. R., Escalante, R., Gazmuri, R. J., Guerguerian, A. -M., Hazinski, M. F., Kudenchuk, P. J., Lofgren, B., Maconochie, I., Mancini, M. E., Meaney, P. A., Neumar, R. W., K. -C., Ng, Nicholson, T. C., Nishiyama, C., Nuthall, G. A., Olasveengen, T. M., Paiva, E. F., Parr, M. J., Reis, A. G., Reynolds, J. C., Ristagno, G., Sandroni, Claudio, Schexnayder, S. M., Scholefield, B. R., Smyth, M. A., Stanton, D., Tijssen, J. A., Vaillancourt, C., Van de Voorde, P., Wang, T. -L., and Welsford, M.

Subjects
AHA Scientific Statements, sudden, cardiac, death, Settore MED/41 - ANESTESIOLOGIA, cardiac arrest, cardiopulmonary resuscitation, death, sudden, cardiac, in-hospital cardiac arrest
Published
2019

47. 2019 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science with Treatment Recommendations: Summary from the Basic Life Support; Advanced Life Support; Pediatric Life Support; Neonatal Life Support; Education, Implementation, and Teams; And First Aid Task Forces

Author

Soar, J., Maconochie, I., Wyckoff, M. H., Olasveengen, T. M., Singletary, E. M., Greif, R., Aickin, R., Bhanji, F., Donnino, M. W., Mancini, M. E., Wyllie, J. P., Zideman, D., Andersen, L. W., Atkins, D. L., Aziz, K., Bendall, J., Berg, K. M., Berry, D. C., Bigham, B. L., Bingham, R., Couto, T. B., Bottiger, B. W., Borra, V., Bray, J. E., Breckwoldt, J., Brooks, S. C., Buick, J., Callaway, C. W., Carlson, J. N., Cassan, P., Castren, M., Chang, W. -T., Charlton, N. P., Cheng, A., Chung, S. P., Considine, J., Couper, K., Dainty, K. N., Dawson, J. A., De Almeida, M. F., De Caen, A. R., Deakin, C. D., Drennan, I. R., Duff, J. P., Epstein, J. L., Escalante, R., Gazmuri, R. J., Gilfoyle, E., Granfeldt, A., Guerguerian, A. -M., Guinsburg, R., Hatanaka, T., Holmberg, M. J., Hood, N., Hosono, S., Hsieh, M. -J., Isayama, T., Iwami, T., Jensen, J. L., Kapadia, V., Kim, H. -S., Kleinman, M. E., Kudenchuk, P. J., Lang, E., Lavonas, E., Liley, H., Lim, S. H., Lockey, A., Lofgren, B., Ma, M. H. -M., Markenson, D., Meaney, P. A., Meyran, D., Mildenhall, L., Monsieurs, K. G., Montgomery, W., Morley, P. T., Morrison, L. J., Nadkarni, V. M., Nation, K., Neumar, R. W., Ng, K. -C., Nicholson, T., Nikolaou, N., Nishiyama, C., Nuthall, G., Ohshimo, S., Okamoto, D., O'Neil, B., Yong-Kwang Ong, G., Paiva, E. F., Parr, M., Pellegrino, J. L., Perkins, G. D., Perlman, J., Rabi, Y., Reis, A., Reynolds, J. C., Ristagno, G., Roehr, C. C., Sakamoto, T., Sandroni, Claudio, Schexnayder, S. M., Scholefield, B. R., Shimizu, N., Skrifvars, M. B., Smyth, M. A., Stanton, D., Swain, J., Szyld, E., Tijssen, J., Travers, A., Trevisanuto, D., Vaillancourt, C., Van De Voorde, P., Velaphi, S., Wang, T. -L., Weiner, G., Welsford, M., Woodin, J. A., Yeung, J., Nolan, J. P., Fran Hazinski, M., Sandroni C. (ORCID:0000-0002-8878-2611), Soar, J., Maconochie, I., Wyckoff, M. H., Olasveengen, T. M., Singletary, E. M., Greif, R., Aickin, R., Bhanji, F., Donnino, M. W., Mancini, M. E., Wyllie, J. P., Zideman, D., Andersen, L. W., Atkins, D. L., Aziz, K., Bendall, J., Berg, K. M., Berry, D. C., Bigham, B. L., Bingham, R., Couto, T. B., Bottiger, B. W., Borra, V., Bray, J. E., Breckwoldt, J., Brooks, S. C., Buick, J., Callaway, C. W., Carlson, J. N., Cassan, P., Castren, M., Chang, W. -T., Charlton, N. P., Cheng, A., Chung, S. P., Considine, J., Couper, K., Dainty, K. N., Dawson, J. A., De Almeida, M. F., De Caen, A. R., Deakin, C. D., Drennan, I. R., Duff, J. P., Epstein, J. L., Escalante, R., Gazmuri, R. J., Gilfoyle, E., Granfeldt, A., Guerguerian, A. -M., Guinsburg, R., Hatanaka, T., Holmberg, M. J., Hood, N., Hosono, S., Hsieh, M. -J., Isayama, T., Iwami, T., Jensen, J. L., Kapadia, V., Kim, H. -S., Kleinman, M. E., Kudenchuk, P. J., Lang, E., Lavonas, E., Liley, H., Lim, S. H., Lockey, A., Lofgren, B., Ma, M. H. -M., Markenson, D., Meaney, P. A., Meyran, D., Mildenhall, L., Monsieurs, K. G., Montgomery, W., Morley, P. T., Morrison, L. J., Nadkarni, V. M., Nation, K., Neumar, R. W., Ng, K. -C., Nicholson, T., Nikolaou, N., Nishiyama, C., Nuthall, G., Ohshimo, S., Okamoto, D., O'Neil, B., Yong-Kwang Ong, G., Paiva, E. F., Parr, M., Pellegrino, J. L., Perkins, G. D., Perlman, J., Rabi, Y., Reis, A., Reynolds, J. C., Ristagno, G., Roehr, C. C., Sakamoto, T., Sandroni, Claudio, Schexnayder, S. M., Scholefield, B. R., Shimizu, N., Skrifvars, M. B., Smyth, M. A., Stanton, D., Swain, J., Szyld, E., Tijssen, J., Travers, A., Trevisanuto, D., Vaillancourt, C., Van De Voorde, P., Velaphi, S., Wang, T. -L., Weiner, G., Welsford, M., Woodin, J. A., Yeung, J., Nolan, J. P., Fran Hazinski, M., and Sandroni C. (ORCID:0000-0002-8878-2611)

Abstract

The International Liaison Committee on Resuscitation has initiated a continuous review of new, peer-reviewed, published cardiopulmonary resuscitation science. This is the third annual summary of the International Liaison Committee on Resuscitation International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations. It addresses the most recent published resuscitation evidence reviewed by International Liaison Committee on Resuscitation Task Force science experts. This summary addresses the role of cardiac arrest centers and dispatcher-assisted cardiopulmonary resuscitation, the role of extracorporeal cardiopulmonary resuscitation in adults and children, vasopressors in adults, advanced airway interventions in adults and children, targeted temperature management in children after cardiac arrest, initial oxygen concentration during resuscitation of newborns, and interventions for presyncope by first aid providers. Members from 6 International Liaison Committee on Resuscitation task forces have assessed, discussed, and debated the certainty of the evidence on the basis of the Grading of Recommendations, Assessment, Development, and Evaluation criteria, and their statements include consensus treatment recommendations. Insights into the deliberations of the task forces are provided in the Justification and Evidence to Decision Framework Highlights sections. The task forces also listed priority knowledge gaps for further research.

Published
2019

48. 2019 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations

Author

Soar, J., Maconochie, I., Wyckoff, M. H., Olasveengen, T. M., Singletary, E. M., Greif, R., Aickin, R., Bhanji, F., Donnino, M. W., Mancini, M. E., Wyllie, J. P., Zideman, D., Andersen, L. W., Atkins, D. L., Aziz, K., Bendall, J., Berg, K. M., Berry, D. C., Bigham, B. L., Bingham, R., Couto, T. B., Bottiger, B. W., Borra, V., Bray, J. E., Breckwoldt, J., Brooks, S. C., Buick, J., Callaway, C. W., Carlson, J. N., Cassan, P., Castren, M., Chang, W. -T., Charlton, N. P., Cheng, A., Chung, S. P., Considine, J., Couper, K., Dainty, K. N., Dawson, J. A., de Almeida, M. F., de Caen, A. R., Deakin, C. D., Drennan, I. R., Duff, J. P., Epstein, J. L., Escalante, R., Gazmuri, R. J., Gilfoyle, E., Granfeldt, A., Guerguerian, A. -M., Guinsburg, R., Hatanaka, T., Holmberg, M. J., Hood, N., Hosono, S., Hsieh, M. -J., Isayama, T., Iwami, T., Jensen, J. L., Kapadia, V., Kim, H. -S., Kleinman, M. E., Kudenchuk, P. J., Lang, E., Lavonas, E., Liley, H., Lim, S. H., Lockey, A., Lofgren, B., Ma, M. H. -M., Markenson, D., Meaney, P. A., Meyran, D., Mildenhall, L., Monsieurs, K. G., Montgomery, W., Morley, P. T., Morrison, L. J., Nadkarni, V. M., Nation, K., Neumar, R. W., Ng, K. -C., Nicholson, T., Nikolaou, N., Nishiyama, C., Nuthall, G., Ohshimo, S., Okamoto, D., O'Neil, B., Ong, G. Y. -K., Paiva, E. F., Parr, M., Pellegrino, J. L., Perkins, G. D., Perlman, J., Rabi, Y., Reis, A., Reynolds, J. C., Ristagno, G., Roehr, C. C., Sakamoto, T., Sandroni, C., Schexnayder, S. M., Scholefield, B. R., Shimizu, N., Skrifvars, M. B., Smyth, M. A., Stanton, D., Swain, J., Szyld, E., Tijssen, J., Travers, A., Trevisanuto, D., Vaillancourt, C., Van de Voorde, P., Velaphi, S., Wang, T. -L., Weiner, G., Welsford, M., Woodin, J. A., Yeung, J., Nolan, J. P., Hazinski, M. F., Sandroni C. (ORCID:0000-0002-8878-2611), Soar, J., Maconochie, I., Wyckoff, M. H., Olasveengen, T. M., Singletary, E. M., Greif, R., Aickin, R., Bhanji, F., Donnino, M. W., Mancini, M. E., Wyllie, J. P., Zideman, D., Andersen, L. W., Atkins, D. L., Aziz, K., Bendall, J., Berg, K. M., Berry, D. C., Bigham, B. L., Bingham, R., Couto, T. B., Bottiger, B. W., Borra, V., Bray, J. E., Breckwoldt, J., Brooks, S. C., Buick, J., Callaway, C. W., Carlson, J. N., Cassan, P., Castren, M., Chang, W. -T., Charlton, N. P., Cheng, A., Chung, S. P., Considine, J., Couper, K., Dainty, K. N., Dawson, J. A., de Almeida, M. F., de Caen, A. R., Deakin, C. D., Drennan, I. R., Duff, J. P., Epstein, J. L., Escalante, R., Gazmuri, R. J., Gilfoyle, E., Granfeldt, A., Guerguerian, A. -M., Guinsburg, R., Hatanaka, T., Holmberg, M. J., Hood, N., Hosono, S., Hsieh, M. -J., Isayama, T., Iwami, T., Jensen, J. L., Kapadia, V., Kim, H. -S., Kleinman, M. E., Kudenchuk, P. J., Lang, E., Lavonas, E., Liley, H., Lim, S. H., Lockey, A., Lofgren, B., Ma, M. H. -M., Markenson, D., Meaney, P. A., Meyran, D., Mildenhall, L., Monsieurs, K. G., Montgomery, W., Morley, P. T., Morrison, L. J., Nadkarni, V. M., Nation, K., Neumar, R. W., Ng, K. -C., Nicholson, T., Nikolaou, N., Nishiyama, C., Nuthall, G., Ohshimo, S., Okamoto, D., O'Neil, B., Ong, G. Y. -K., Paiva, E. F., Parr, M., Pellegrino, J. L., Perkins, G. D., Perlman, J., Rabi, Y., Reis, A., Reynolds, J. C., Ristagno, G., Roehr, C. C., Sakamoto, T., Sandroni, C., Schexnayder, S. M., Scholefield, B. R., Shimizu, N., Skrifvars, M. B., Smyth, M. A., Stanton, D., Swain, J., Szyld, E., Tijssen, J., Travers, A., Trevisanuto, D., Vaillancourt, C., Van de Voorde, P., Velaphi, S., Wang, T. -L., Weiner, G., Welsford, M., Woodin, J. A., Yeung, J., Nolan, J. P., Hazinski, M. F., and Sandroni C. (ORCID:0000-0002-8878-2611)

Abstract

The International Liaison Committee on Resuscitation has initiated a continuous review of new, peer-reviewed, published cardiopulmonary resuscitation science. This is the third annual summary of the International Liaison Committee on Resuscitation International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations. It addresses the most recent published resuscitation evidence reviewed by International Liaison Committee on Resuscitation Task Force science experts. This summary addresses the role of cardiac arrest centers and dispatcher-assisted cardiopulmonary resuscitation, the role of extracorporeal cardiopulmonary resuscitation in adults and children, vasopressors in adults, advanced airway interventions in adults and children, targeted temperature management in children after cardiac arrest, initial oxygen concentration during resuscitation of newborns, and interventions for presyncope by first aid providers. Members from 6 International Liaison Committee on Resuscitation task forces have assessed, discussed, and debated the certainty of the evidence on the basis of the Grading of Recommendations, Assessment, Development, and Evaluation criteria, and their statements include consensus treatment recommendations. Insights into the deliberations of the task forces are provided in the Justification and Evidence to Decision Framework Highlights sections. The task forces also listed priority knowledge gaps for further research.

Published
2019

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