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2. Contributors

Author

Abou-Zamzam, Ahmed M., primary, Abularrage, Christopher J., additional, AbuRahma, Ali F., additional, Acosta, Stefan, additional, Adams, Harold P., additional, Aidinian, Gilbert, additional, Akar, A. Ruchan, additional, Alimi, Yves S., additional, Andros, George, additional, Arcelus, Juan I., additional, Armstrong, David G., additional, Armstrong, Paul A., additional, Arora, Subodh, additional, Arthurs, Zachary M., additional, Ascher, Enrico, additional, Atkins, Marvin D., additional, Atnip, Robert G., additional, Aziz, Faisal, additional, Back, Martin R., additional, Ballard, Jeffrey L., additional, Bandyk, Dennis F., additional, Bartholomew, John R., additional, Baumeister, Ruediger G.H., additional, Bavaria, Joseph E., additional, Bechara, Carlos F., additional, Belkin, Michael, additional, Berceli, Scott A., additional, Bernas, Michael J., additional, Björck, Martin, additional, Black, James H., additional, Blankensteijn, Jan D., additional, Bower, Thomas C., additional, Brinkman, William T., additional, Brummel-Ziedins, Kathleen E., additional, Bush, Ruth L., additional, Calligaro, Keith D., additional, Cambria, Richard P., additional, Cao, Piergiorgio, additional, Caprini, Joseph A., additional, Carlson, Gregory D., additional, Carleton, T. Johelen, additional, Carpenter, Jeffrey P., additional, Chaikof, Elliot L., additional, Charlton-Ouw, Kristofer M., additional, Cheng, Stephen W.K., additional, Cho, Jae Sung, additional, Chuter, Timothy A.M., additional, Cinà, Claudio S., additional, Clair, Daniel G., additional, Clouse, W. Darrin, additional, Coggia, Marc, additional, Coimbra, Raul, additional, Comerota, Anthony J., additional, Conrad, Mark F., additional, Cooper, Leslie T., additional, Conte, Michael S., additional, Corriere, Matthew A., additional, Crawford, Robert S., additional, Cull, David L., additional, Dalman, Ronald L., additional, Dalsing, Michael C., additional, Dardik, Alan, additional, Darling, R. Clement, additional, Davies, Mark G., additional, DeLoach, Stephanie S., additional, Demetriades, Demetrios, additional, DePalma, Ralph G., additional, De Rango, Paola, additional, Dosluoglu, Hasan H., additional, Dougherty, Matthew J., additional, Driskill, Matt, additional, Duncan, Audra A., additional, Durdu, Serkan, additional, Earnshaw, Jonothan J., additional, Eberhardt, Robert T., additional, Edwards, James M., additional, Edwards, Matthew S., additional, Eidt, John F., additional, Endean, Eric, additional, Eskandari, Mark K., additional, Farber, Alik, additional, Faries, Peter L., additional, Fillinger, Mark F., additional, Fishman, Steven J., additional, Fitzgerald, Tamara N., additional, Forbes, Thomas L., additional, Fox, Charles J., additional, Gamble, Gail L., additional, Garvin, Robert P., additional, Geary, Randolph L., additional, Gillespie, David L., additional, Gloviczki, Peter, additional, Godshall, Christopher J., additional, Goëau-Brissonnière, Olivier, additional, Gornik, Heather L., additional, Gottsäter, Anders, additional, Greenberg, Roy K., additional, Greene, Arin K., additional, Griffith, Nathan M., additional, Guttmann, Geoffrey D., additional, Guzman, Raul J., additional, Hamdan, Allen, additional, Hamming, Jaap F., additional, Hansen, Kimberley J., additional, Harris, Linda M., additional, Hartung, Olivier, additional, Henke, Peter K., additional, Hingorani, Anil P., additional, Hoballah, Jamal J., additional, Hodgson, Kim J., additional, Hood, Douglas B., additional, Howard, Wm. James, additional, Hoyt, David B., additional, Huang, Christina, additional, Huber, Thomas S., additional, Hunter, Glenn C., additional, Iafrati, Mark D., additional, Illig, Karl A., additional, Inaba, Kenji, additional, Jacobowitz, Glenn R., additional, Jacobs, Michael J., additional, Jimenez, Juan Carlos, additional, Jordan, William D., additional, Kabnick, Lowell S., additional, Kalapatapu, Venkat R., additional, Kalra, Manju, additional, Kashyap, Vikram S., additional, Kasirajan, Karthikeshwar, additional, Kauffman, Paulo, additional, Killewich, Lois A., additional, Kim, Esther S.H., additional, Kohler, Ted R., additional, Kresowik, Timothy F., additional, Labropoulos, Nicos, additional, Lal, Brajesh K., additional, Landry, Gregory J., additional, Lau, David L., additional, Lavery, Lawrence A., additional, Lawrence, Peter F., additional, Lawson, Jeffrey H., additional, Lee, Byung-Boong, additional, Lee, W. Anthony, additional, León, Luis R., additional, Lew, Wesley K., additional, Liapis, Christos, additional, Liebman, Howard A., additional, Lilly, Michael P., additional, Lin, Peter H., additional, Lindblad, Bengt, additional, Lindsay, Thomas F., additional, Lipsett, Pamela A., additional, Litt, Harold, additional, Locke, Jayme E., additional, Lohr, Joann, additional, Longo, G. Matthew, additional, Lumsden, Alan B., additional, Lurie, Fedor, additional, Lynch, Thomas G., additional, Mackey, William C., additional, Macsata, Robyn A., additional, Makaroun, Michel S., additional, Maldonado, Thomas S., additional, Mann, Kenneth G., additional, Markose, George, additional, Marston, William A., additional, Martinez, Carlo O., additional, Matsumura, Jon S., additional, McKinsey, James F., additional, McLafferty, Robert B., additional, Meier, George H., additional, Menard, Matthew T., additional, Messina, Louis M., additional, Mills, Joseph L., additional, Modrall, J. Gregory, additional, Mohler, Emile, additional, Moneta, Gregory L., additional, Morasch, Mark D., additional, Myers, Stuart I., additional, Naylor, A. Ross, additional, Neglén, Peter, additional, Nguyen, Louis L., additional, O'Donnell, Thomas F., additional, O’Hara, Patrick J., additional, Ohki, Takao, additional, Oldenburg, W. Andrew, additional, Olin, Jeffrey W., additional, Owens, Christopher D., additional, Papia, Giuseppe, additional, Partsch, Hugo, additional, Passman, Marc A., additional, Patel, Himanshu J., additional, Patel, Kaushal R., additional, Pearce, Benjamin, additional, Perler, Bruce A., additional, Poldermans, Don, additional, Pomposelli, Frank B., additional, Pounds, Lori L., additional, Powell, Richard J., additional, Puggioni, Alessandra, additional, Qu, Zheng, additional, Quinn, Brendon M., additional, Quinones-Baldrich, William J., additional, Raffetto, Joseph D., additional, Raju, Seshadri, additional, Rana, Nabeel R., additional, Rasmussen, Todd E., additional, Reddy, Daniel J., additional, Rigberg, David, additional, Rockman, Caron B., additional, Rockson, Stanley G., additional, Roddy, Sean P., additional, Rogers, Lee C., additional, Roseborough, Glen S., additional, Rowe, Vincent L., additional, Rubin, Brian G., additional, Rzucidlo, Eva M., additional, Sadek, Mikel, additional, Safi, Hazim J., additional, Sambol, Elliot B., additional, Sanders, Richard J., additional, Schanzer, Andres, additional, Schneider, Darren, additional, Schneider, Joseph R., additional, Schneider, Peter A., additional, Schouten, Olaf, additional, Schroeder, Torben V., additional, Kool, Leo J. Schultze, additional, Schumacher, Paul M., additional, Schurink, Geert Willem, additional, Sheehan, Peter, additional, Shireman, Paula K., additional, Sicard, Gregorio A., additional, Sidawy, Anton N., additional, Sileshi, Bantayehu, additional, Singh, Niten N., additional, Smith, Stephen T., additional, Starnes, Benjamin W., additional, Sternbergh, W. Charles, additional, Stone, David H., additional, Sumi, Makoto, additional, Sumner, David S., additional, Sumpio, Bauer, additional, Svensson, Lars G., additional, Taylor, Spence M., additional, Tedesco, Maureen M., additional, Tillman, Bryan W., additional, Thompson, Robert W., additional, Timaran, Carlos H., additional, Upchurch, Gilbert R., additional, Valentine, R. James, additional, van Bockel, J. Hajo, additional, Vandy, Frank C., additional, Villavicencio, Leonel, additional, Vogt, Katja C., additional, Wakefield, Thomas W., additional, Walcott, Roger, additional, Walsh, Daniel B., additional, Warrington, Kenneth J., additional, Watkins, Michael T., additional, Weaver, Fred A., additional, Weaver, Mitchell R., additional, Weitz, Ilene C., additional, White, John V., additional, Wietz, Jeffrey I., additional, Witte, Marlys H., additional, Wolosker, Nelson, additional, Wyers, Mark C., additional, York, John W., additional, Zhang, Wayne W., additional, and Zierler, R. Eugene, additional

Published
2010
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7. Systolic hypertension: a guide to optimal therapy

Author

DeLoach, Stephanie S. and Townsend, Raymond R.

Subjects
Coronary heart disease -- Risk factors -- Diagnosis -- Care and treatment -- Complications and side effects, Hypertension -- Risk factors -- Diagnosis -- Care and treatment -- Complications and side effects, Health, Diagnosis, Care and treatment, Complications and side effects, Risk factors
Abstract

ABSTRACT: Systolic hypertension is an independent risk factor for coronary artery disease, stroke, and end-stage renal disease. Nonpharmacological interventions for systolic hypertension include limitation of dietary sodium and alcohol intake [...]

Published
2008

8. Associations of cardiac structure with obesity, blood pressure, inflammation, and insulin resistance in African-American adolescents.

Author

Gidding, Samuel S, Palermo, Robert A, DeLoach, Stephanie S, Keith, Scott W, Falkner, Bonita, Gidding, Samuel S, Palermo, Robert A, DeLoach, Stephanie S, Keith, Scott W, and Falkner, Bonita

Abstract

To determine if obesity, blood pressure (BP), markers of inflammation, and insulin resistance are associated with cardiac structure in African-American adolescents, a cross-sectional study was performed on a cohort oversampled for high BP and obesity. Measurements included the following: anthropometrics, BP, homeostasis model assessment (HOMA) to assess insulin resistance, high-sensitivity C-reactive protein, and plasma adipokines (adiponectin, interleukin-6, plasminogen activator inhibitor-1). Echocardiogram measurements were left-ventricular mass index (LVMI) (g/m(2.7)), LV relative wall thickness (LVRWT), left-atrial diameter index [LADI (mm/m)], and LV diastolic time intervals. LADI (r (2) = 0.25) was associated with body mass index (BMI) systolic BP (SBP) and female sex. LVMI (r (2) = 0.35) variation was associated with BMI SBP, heart rate, age, and male sex. LVRWT (r (2) = 0.05) was associated with HOMA. Tissue diastolic intervals were not associated with any risk factor. Inflammatory markers and adipokines were associated with BMI but were not independently associated with any echocardiographic measures. In African-American adolescents, BMI and SBP, but not inflammatory markers or adipokines, are important correlates of LA size and LVM.

Published
2014

11. Cardiovascular disease in chronic kidney disease. A clinical update from Kidney Disease: Improving Global Outcomes (KDIGO)

Author

Herzog, Charles A., primary, Asinger, Richard W., additional, Berger, Alan K., additional, Charytan, David M., additional, Díez, Javier, additional, Hart, Robert G., additional, Eckardt, Kai-Uwe, additional, Kasiske, Bertram L., additional, McCullough, Peter A., additional, Passman, Rod S., additional, DeLoach, Stephanie S., additional, Pun, Patrick H., additional, and Ritz, Eberhard, additional

Published
2011
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16. Central Blood Pressures Are Associated With Left Ventricular Mass Index Among African-American Adolescents.

Author

DeLoach, Stephanie S., Daskalakis, Constantine, Gidding, Samuel, and Falkner, Bonita

Subjects
BLOOD pressure, HEART physiology, LEFT heart ventricle, AFRICAN American teenagers, CARDIOVASCULAR diseases, COHORT analysis, HEALTH
Abstract

BackgroundThere is a high burden of premature cardiovascular disease (CVD) among African Americans. Measures of central aortic blood pressure (CASP) and wave reflection are predictive of CVD risk in adults, but there is a paucity of data regarding the relation of these measures to target organ damage among adolescents. The objective of this study was to examine the relationship between CASP, central pulse pressure (CPP), and augmentation index (AI) with left ventricular mass index (LVMI).MethodsA cohort of 120 African-American adolescents was examined. Study participants underwent measurement of peripheral blood pressure (BP) using auscultation, pulse wave analysis (PWA) for determination of CASP, CPP, and AI, and echocardiography for determination of LVMI.ResultsThe cohort was 55% male, with mean BP 114/62 mm Hg, mean LVMI 36 g/m2.7, mean CASP 94 mm Hg, mean CPP 31 mmHg, and mean AI was 0.5%. After adjustment for potential confounders, peripheral systolic BP (SBP) was significantly associated with LVMI (P = 0.008), but diastolic pressure was not (P = 0.887). The CASP and CPP were significantly associated with LVMI (P = 0.020 and 0.005, respectively). Peripheral SBP, CASP, and CPP had similar associations with respect to LVMI (r2 = 0.26, 0. 26, and 0.27, respectively).ConclusionCentral BP is associated with LVMI among African-American adolescents, and these associations are similar to those seen with peripheral BP measurements.American Journal of Hypertension (2012). doi:10.1038/ajh.2011.174 [ABSTRACT FROM AUTHOR]

Published
2012
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17. Living Donor Kidney Donation: Another Form of White Coat Effect.

Author

DeLoach, Stephanie S., Meyers, Kevin E.C., and Townsend, Raymond R.

Abstract

Background/Aims: Living donor nephrectomy can be associated with increases in blood pressure several years following the procedure, but the best method to assess blood pressure during the living donor evaluation process is unclear. Methods: Living kidney donors underwent casual clinic and ambulatory blood pressure monitoring (ABPM) and measurement of central aortic pressures at baseline and 6 months following donor nephrectomy. Results: There was a significant decline in clinic systolic blood pressure (SBP; p = 0.001) and central aortic systolic pressure (p = 0.011) during the study period. However, average ABPM was unchanged and other measures of central arterial pressures and Augmentation Index were unchanged at 6 months compared to baseline. Conclusions: The remarkable differences between clinic SBP and ambulatory SBP prior to donation, and the disappearance of these differences 6 months later, suggest a substantial white coat effect on SBP associated with living kidney donor evaluation. Also, ABPM represents a better way to assess blood pressure prior to kidney donation. Copyright © 2011 S. Karger AG, Basel [ABSTRACT FROM AUTHOR]

Published
2012
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18. Aortic Pulse Pressure Is Associated With Carotid IMT in Chronic Kidney Disease: Report From Chronic Renal Insufficiency Cohort.

Author

DeLoach, Stephanie S., Appel, Lawrence J., Jing Chen, Joffe, Marshall M., Gadegbeku, Crystal A., Mohler III, Emile R., Parsa, Afshin, Perumal, Kalyani, Rafey, Mohammed A., Steigerwalt, Susan P., Teal, Valerie, Townsend, Raymond R., and Rosas, Sylvia E.

Subjects
CHRONIC kidney failure, KIDNEY diseases, CARDIOVASCULAR diseases, GLOMERULAR filtration rate
Abstract

BackgroundPatients with chronic kidney disease (CKD) have a disproportionate risk of cardiovascular disease. This study was designed to assess the association between two noninvasive measures of cardiovascular risk, pulse wave analysis (PWA), and carotid intima-media thickness (IMT), in a cohort of CKD patients enrolled in the Chronic Renal Insufficiency Cohort (CRIC) study.MethodsThree hundred and sixty-seven subjects with CKD enrolled in the CRIC study at the University of Pennsylvania site (mean age 59.9 years, blood pressure 129/74 mm Hg, estimated glomerular filtration rate 48 ml/min/1.73 m2, IMT 0.8 mm) had both carotid IMT and PWA measurements. Carotid ultrasound was also used to determine the presence of plaque. PWA was used to determine augmentation index (AI), amplification ratio (AMPR), aortic pulse pressure (C_PP), and central aortic systolic pressure (C_SP).ResultsIMT was significantly associated with all PWA-derived measures. However, on multivariable linear regression analysis, only AMPR (regression coefficient −0.072, P = 0.006), C_PP (regression coefficient 0.0025, P < 0.001), and C_SP (regression coefficient 0.0017, P < 0.001) remained significantly associated with IMT. The prevalence of carotid plaque in the cohort was 59%. Of the PWA-derived measures, only C_PP was significantly associated with the presence of carotid plaque (P < 0.001).ConclusionsPWA-derived measures are associated with carotid IMT and plaque in the CKD. Of these measures, C_PP was most associated with carotid IMT and plaque.American Journal of Hypertension 2009; doi:10.1038/ajh.2009.156 [ABSTRACT FROM AUTHOR]

Published
2009
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19. Peripheral arterial disease: a guide for nephrologists.

Author

DeLoach SS and Mohler ER 3rd

Subjects
Humans, Nephrology, Peripheral Vascular Diseases diagnosis, Peripheral Vascular Diseases epidemiology, Peripheral Vascular Diseases therapy, Practice Guidelines as Topic, Risk Factors, Kidney Diseases complications, Peripheral Vascular Diseases etiology
Abstract

Cardiovascular disease is a major source of morbidity and mortality for patients with chronic kidney disease (CKD). Peripheral arterial disease (PAD) is a strong predictor of coronary artery disease and a risk factor for mortality in the general population. This is of particular interest to nephrologists because the risk for PAD is increased in CKD. Often, PAD is overlooked as a source of morbidity and as a cardiovascular risk factor in this population. This review serves as an overview of the epidemiology, screening, diagnosis, and treatment of PAD with an emphasis on CKD.

Published
2007
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