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Your search keyword '"De Vries, Paul S"' showing total 693 results

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1. Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification

2. Rare variant contribution to the heritability of coronary artery disease

4. Investigating Gene-Diet Interactions Impacting the Association Between Macronutrient Intake and Glycemic Traits.

5. Whole-genome sequencing uncovers two loci for coronary artery calcification and identifies ARSE as a regulator of vascular calcification

6. Powerful, scalable and resource-efficient meta-analysis of rare variant associations in large whole genome sequencing studies

7. Coronary heart disease and ischemic stroke polygenic risk scores and atherosclerotic cardiovascular disease in a diverse, population-based cohort study.

8. Correlations between complex human phenotypes vary by genetic background, gender, and environment

9. A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies

10. Rare coding variants in RCN3 are associated with blood pressure

12. Insights From a Large-Scale Whole-Genome Sequencing Study of Systolic Blood Pressure, Diastolic Blood Pressure, and Hypertension

13. Multi‐phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations

14. Genetic insights into resting heart rate and its role in cardiovascular disease

15. Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locus

16. Type 2 Diabetes Partitioned Polygenic Scores Associate With Disease Outcomes in 454,193 Individuals Across 13 Cohorts

17. A genetic association study of circulating coagulation factor VIII and von Willebrand factor levels

18. A multitrait genetic study of hemostatic factors and hemorrhagic transformation after stroke treatment

19. Whole genome sequence analysis of platelet traits in the NHLBI Trans-Omics for Precision Medicine (TOPMed) initiative

20. Whole genome sequence analysis of blood lipid levels in >66,000 individuals

21. Whole genome sequencing identifies structural variants contributing to hematologic traits in the NHLBI TOPMed program

22. Whole genome sequence association analysis of fasting glucose and fasting insulin levels in diverse cohorts from the NHLBI TOPMed program

23. Multi-ancestry genome-wide gene–sleep interactions identify novel loci for blood pressure

24. A System for Phenotype Harmonization in the National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine (TOPMed) Program

25. Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program

27. Whole-genome analysis of plasma fibrinogen reveals population-differentiated genetic regulators with putative liver roles

28. FGL1 as a modulator of plasma D‐dimer levels: Exome‐wide marker analysis of plasma tPA, PAI‐1, and D‐dimer

29. Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci.

30. Whole-genome sequencing association analysis of quantitative red blood cell phenotypes: The NHLBI TOPMed program

31. Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices.

32. Multi-ancestry genome-wide association study accounting for gene-psychosocial factor interactions identifies novel loci for blood pressure traits

33. Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants

34. Role of Rare and Low-Frequency Variants in Gene-Alcohol Interactions on Plasma Lipid Levels

35. Genetic loci associated with prevalent and incident myocardial infarction and coronary heart disease in the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium

36. Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations.

37. Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium

38. DNA methylation analysis is used to identify novel genetic loci associated with circulating fibrinogen levels in blood

40. Gene-lifestyle interactions in the genomics of human complex traits

41. Antithrombin, PC (Protein C), and PS (Protein S): Genome and Transcriptome-Wide Association Studies Identify 7 Novel Loci Regulating Plasma Levels

42. Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration.

43. Impact of Rare and Common Genetic Variants on Diabetes Diagnosis by Hemoglobin A1c in Multi-Ancestry Cohorts: The Trans-Omics for Precision Medicine Program

44. Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions

45. Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls

46. Leveraging linkage evidence to identify low-frequency and rare variants on 16p13 associated with blood pressure using TOPMed whole genome sequencing data

47. Efficient Variant Set Mixed Model Association Tests for Continuous and Binary Traits in Large-Scale Whole-Genome Sequencing Studies

48. Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels

49. Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.

50. Mendelian randomization evaluation of causal effects of fibrinogen on incident coronary heart disease

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