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1. The Southern Wide-Field Gamma-Ray Observatory (SWGO): A Next-Generation Ground-Based Survey Instrument for VHE Gamma-Ray Astronomy

Author

Abreu, P., Albert, A., Alfaro, R., Alvarez, C., Arceo, R., Assis, P., Barao, F., Bazo, J., Beacom, J. F., Bellido, J., BenZvi, S., Bretz, T., Brisbois, C., Brown, A. M., Brun, F., Buscemi, M., Mora, K. S. Caballero, Camarri, P., Carramiñana, A., Casanova, S., Chiavassa, A., Conceição, R., Cotter, G., Cristofari, P., Dasso, S., De Angelis, A., De Maria, M., Desiati, P., Di Sciascio, G., Vélez, J. C. Díaz, Dib, C., Dingus, B., Dorner, D., Doro, M., Duffy, C., DuVernois, M., Engel, R., Alonso, M. Fernandez, Fleischhack, H., Fonte, P., Fraija, N., Funk, S., García-González, J. A., González, M. M., Goodman, J. A., Greenshaw, T., Harding, J. P., Haungs, A., Hona, B., Huentemeyer, P., Insolia, A., Jardin-Blicq, A., Joshi, V., Kawata, K., Kunwar, S., La Mura, G., Lapington, J., Lenain, J. P., López-Coto, R., Malone, K., Martinez-Castro, J., Martínez-Huerta, H., Mendes, L., Moreno, E., Mostafá, M., Ng, K. C. Y., Nisa, M. U., Peron, F., Pichel, A., Pimenta, M., Prandini, E., Rainò, S., Reisenegger, A., Rodriguez, J., Roth, M., Rovero, A., Ruiz-Velasco, E., Sako, T., Sandoval, A., Santander, M., Satalecka, K., Schneider, M., Schoorlemmer, H., Schüssler, F., Shellard, R. C., Smith, A., Spencer, S., Springer, W., Surajbali, P., Tollefson, K., Tomé, B., Torres, I., Viana, A., Weisgarber, T., Wischnewski, R., Zepeda, A., Zhou, B., and Zhou, H.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - High Energy Astrophysical Phenomena
Abstract

We describe plans for the development of the Southern Wide-field Gamma-ray Observatory (SWGO), a next-generation instrument with sensitivity to the very-high-energy (VHE) band to be constructed in the Southern Hemisphere. SWGO will provide wide-field coverage of a large portion of the southern sky, effectively complementing current and future instruments in the global multi-messenger effort to understand extreme astrophysical phenomena throughout the universe. A detailed description of science topics addressed by SWGO is available in the science case white paper [1]. The development of SWGO will draw on extensive experience within the community in designing, constructing, and successfully operating wide-field instruments using observations of extensive air showers. The detector will consist of a compact inner array of particle detection units surrounded by a sparser outer array. A key advantage of the design of SWGO is that it can be constructed using current, already proven technology. We estimate a construction cost of 54M USD and a cost of 7.5M USD for 5 years of operation, with an anticipated US contribution of 20M USD ensuring that the US will be a driving force for the SWGO effort. The recently formed SWGO collaboration will conduct site selection and detector optimization studies prior to construction, with full operations foreseen to begin in 2026. Throughout this document, references to science white papers submitted to the Astro2020 Decadal Survey with particular relevance to the key science goals of SWGO, which include unveiling Galactic particle accelerators [2-10], exploring the dynamic universe [11-21], and probing physics beyond the Standard Model [22-25], are highlighted in red boldface., Comment: Astro2020 APC White Paper

Published
2019

3. Spectral Energy Distribution of Markarian 501: Quiescent State vs. Extreme Outburst

Author

The VERITAS Collaboration, Acciari, V. A., Arlen, T., Aune, T., Beilicke, M., Benbow, W., Böttcher, M., Boltuch, D., Bradbury, S. M., Buckley, J. H., Bugaev, V., Cannon, A., Cesarini, A., Ciupik, L., Cui, W., Dickherber, R., Duke, C., Errando, M., Falcone, A., Finley, J. P., Finnegan, G., Fortson, L., Furniss, A., Galante, N., Gall, D., Godambe, S., Grube, J., Guenette, R., Gyuk, G., Hanna, D., Holder, J., Huang, D., Hui, C. M., Humensky, T. B., Imran, A., Kaaret, P., Karlsson, N., Kertzman, M., Kieda, D., Konopelko, A., Krawczynski, H., Krennrich, F., Madhavan, A. S, Maier, G., McArthur, S., McCann, A., Moriarty, P., Ong, R. A., Otte, A. N., Pandel, D., Perkins, J. S., Pichel, A., Pohl, M., Quinn, J., Ragan, K., Reyes, L. C., Reynolds, P. T., Roache, E., Rose, H. J., Schroedter, M., Sembroski, G. H., Steele, D., Swordy, S. P., Theiling, M., Thibadeau, S., Varlotta, A., Vassiliev, V. V., Vincent, S., Wakely, S. P., Ward, J. E., Weekes, T. C., Weinstein, A., Weisgarber, T., Williams, D. A., Wood, M., Zitzer, B., Collaboration, The MAGIC, Aleksić, J., Antonelli, L. A., Antoranz, P., Backes, M., Barrio, J. A., Bastieri, D., González, J. Becerra, Bednarek, W., Berdyugin, A., Berger, K., Bernardini, E., Biland, A., Blanch, O., Bock, R. K., Boller, A., Bonnoli, G., Bordas, P., Tridon, D. Borla, Bosch-Ramon, V., Bose, D., Braun, I., Bretz, T., Camara, M., Carmona, E., Carosi, A., Colin, P., Colombo, E., Contreras, J. L., Cortina, J., Covino, S., Dazzi, F., De Angelis, A., del Pozo, E. De Cea, De Lotto, B., De Maria, M., De Sabata, F., Mendez, C. Delgado, Ortega, A. Diago, Doert, M., Domínguez, A., Prester, D. Dominis, Dorner, D., Doro, M., Elsaesser, D., Ferenc, D., Fonseca, M. V., Font, L., López, R. J. García, Garczarczyk, M., Gaug, M., Giavitto, G., Godinović, N., Hadasch, D., Herrero, A., Hildebrand, D., Höhne-Mönch, D., Hose, J., Hrupec, D., Jogler, T., Klepser, S., Krähenbühl, T., Kranich, D., Krause, J., La Barbera, A., Leonardo, E., Lindfors, E., Lombardi, S., Longo, F., López, M., Lorenz, E., Majumdar, P., Makariev, M., Maneva, G., Mankuzhiyil, N., Mannheim, K., Maraschi, L., Mariotti, M., Martínez, M., Mazin, D., Meucci, M., Miranda, J. M., Mirzoyan, R., Miyamoto, H., Moldón, J., Moralejo, A., Nieto, D., Nilsson, K., Orito, R., Oya, I., Paoletti, R., Paredes, J. M., Partini, S., Pasanen, M., Pauss, F., Pegna, R. G., Perez-Torres, M. A., Persic, M., Peruzzo, L., Pochon, J., Prada, F., Moroni, P. G. Prada, Prandini, E., Puchades, N., Puljak, I., Reichardt, I., Reinthal, R., Rhode, W., Ribó, M., Rico, J., Rissi, M., Rügamer, S., Saggion, A., Saito, K., Saito, T. Y., Salvati, M., Sánchez-Conde, M., Satalecka, K., Scalzotto, V., Scapin, V., Schultz, C., Schweizer, T., Shayduk, M., Shore, S. N., Sierpowska-Bartosik, A., Sillanpää, A., Sitarek, J., Sobczynska, D., Spanier, F., Spiro, S., Stamerra, A., Steinke, B., Storz, J., Strah, N., Struebig, J. C., Suric, T., Takalo, L., Tavecchio, F., Temnikov, P., Terzić, T., Tescaro, D., Teshima, M., Torres, D. F., Vankov, H., Wagner, R. M., Weitzel, Q., Zabalza, V., Zandanel, F., Zanin, R., Paneque, D., and Hayashida, M.

Subjects
Astrophysics - High Energy Astrophysical Phenomena
Abstract

The very high energy (VHE; E > 100 GeV) blazar Markarian 501 has a well-studied history of extreme spectral variability and is an excellent laboratory for studying the physical processes within the jets of active galactic nuclei. However, there are few detailed multiwavelength studies of Markarian 501 during its quiescent state, due to its low luminosity. A short-term multiwavelength study of Markarian 501 was coordinated in March 2009, focusing around a multi-day observation with the Suzaku X-ray satellite and including {\gamma}-ray data from VERITAS, MAGIC, and the Fermi Gamma-ray Space Telescope with the goal of providing a well-sampled multiwavelength baseline measurement of Markarian 501 in the quiescent state. The results of these quiescent-state observations are compared to the historically extreme outburst of April 16, 1997, with the goal of examining variability of the spectral energy distribution between the two states. The derived broadband spectral energy distribution shows the characteristic double-peaked profile. We find that the X-ray peak shifts by over two orders of magnitude in photon energy between the two flux states while the VHE peak varies little. The limited shift in the VHE peak can be explained by the transition to the Klein-Nishina regime. Synchrotron self-Compton models are matched to the data and the implied Klein-Nishina effects are explored., Comment: Accepted for publication in ApJ, 25 pages, 6 figures, corresponding authors: Daniel Gall daniel-d-gall@uiowa.edu and Wei Cui cui@purdue.edu

Published
2010
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4. Observations of the Blazar 3C 66A with the MAGIC Telescopes in Stereoscopic Mode

Author

The MAGIC Collaboration, Aleksić, J., Antonelli, L. A., Antoranz, P., Backes, M., Barrio, J. A., Bastieri, D., González, J. Becerra, Bednarek, W., Berdyugin, A., Berger, K., Bernardini, E., Biland, A., Blanch, O., Bock, R. K., Boller, A., Bonnoli, G., Bordas, P., Tridon, D. Borla, Bosch-Ramon, V., Bose, D., Braun, I., Bretz, T., Camara, M., Cañellas, A., Carmona, E., Carosi, A., Colin, P., Colombo, E., Contreras, J. L., Cortina, J., Cossio, L., Covino, S., Dazzi, F., De Angelis, A., del Pozo, E. De Cea, De Lotto, B., De Maria, M., De Sabata, F., Mendez, C. Delgado, Ortega, A. Diago, Doert, M., Domínguez, A., Prester, D. Dominis, Dorner, D., Doro, M., Elsaesser, D., Errando, M., Ferenc, D., Fonseca, M. V., Font, L., López, R. J. García, Garczarczyk, M., Garrido, D., Giavitto, G., Godinović, N., Hadasch, D., Herrero, A., Hildebrand, D., Höhne-Mönch, D., Hose, J., Hrupec, D., Huber, B., Jogler, T., Klepser, S., Krähenbühl, T., Kranich, D., Krause, J., La Barbera, A., Lelas, D., Leonardo, E., Lindfors, E., Lombardi, S., Longo, F., López, M., Lorenz, E., Majumdar, P., Makariev, M., Maneva, G., Mankuzhiyil, N., Mannheim, K., Maraschi, L., Mariotti, M., Martínez, M., Mazin, D., Meucci, M., Miranda, J. M., Mirzoyan, R., Miyamoto, H., Moldón, J., Moralejo, A., Nieto, D., Nilsson, K., Orito, R., Oya, I., Paoletti, R., Pardo, S., Paredes, J. M., Partini, S., Pasanen, M., Pauss, F., Pegna, R. G., Perez-Torres, M. A., Persic, M., Peruzzo, L., Pochon, J., Prada, F., Moroni, P. G. Prada, Prandini, E., Puchades, N., Puljak, I., Reichardt, I., Reinthal, R., Rhode, W., Ribó, M., Rico, J., Rügamer, S., Saggion, A., Saito, K., Saito, T. Y., Salvati, M., Sánchez-Conde, M., Satalecka, K., Scalzotto, V., Scapin, V., Schultz, C., Schweizer, T., Shayduk, M., Shore, S. N., Sierpowska-Bartosik, A., Sillanpää, A., Sitarek, J., Sobczynska, D., Spanier, F., Spiro, S., Stamerra, A., Steinke, B., Storz, J., Strah, N., Struebig, J. C., Surić, T., Takalo, L., Tavecchio, F., Temnikov, P., Terzić, T., Tescaro, D., Teshima, M., Thom, M., Torres, D. F., Vankov, H., Vogler, P., Wagner, R. M., Weitzel, Q., Zabalza, V., Zandanel, F., and Zanin, R.

Subjects
Astrophysics - High Energy Astrophysical Phenomena
Abstract

We report new observations of the intermediate-frequency peaked BL Lacertae object 3C 66A with the MAGIC telescopes. The data sample we use were taken in 2009 December and 2010 January, and comprises 2.3 hr of good quality data in stereoscopic mode. In this period, we find a significant signal from the direction of the blazar 3C 66A. The new MAGIC stereoscopic system is shown to play an essential role for the separation between 3C 66A and the nearby radio galaxy 3C 66B, which is at a distance of only $6^\prime$. The derived integral flux above $100\eh{GeV}$ is 8.3% of Crab Nebula flux and the energy spectrum is reproduced by a power law of photon index $3.64 \pm 0.39_{\rm stat} \pm 0.25_{\rm sys}$. Within errors, this is compatible with the one derived by VERITAS in 2009. From the spectra corrected for absorption by the extragalactic background light, we only find small differences between the four models that we applied, and constrain the redshift of the blazar to $z < 0.68$., Comment: Accepted for publication in ApJ

Published
2010
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5. Detection of very high energy gamma-ray emission from the Perseus cluster head-tail galaxy IC 310 by the MAGIC telescopes

Author

MAGIC Collaboration, Aleksić, J., Antonelli, L. A., Antoranz, P., Backes, M., Barrio, J. A., Bastieri, D., González, J. Becerra, Bednarek, W., Berdyugin, A., Berger, K., Bernardini, E., Biland, A., Blanch, O., Bock, R. K., Boller, A., Bonnoli, G., Bordas, P., Tridon, D. Borla, Bosch-Ramon, V., Bose, D., Braun, I., Bretz, T., Camara, M., Cañellas, A., Carmona, E., Carosi, A., Colin, P., Colombo, E., Contreras, J. L., Cossio, L., Cortina, J., Covino, S., Dazzi, F., De Angelis, A., del Pozo, E. De Cea, De Lotto, B., De Maria, M., De Sabata, F., Mendez, C. Delgado, Ortega, A. Diago, Doert, M., Domínguez, A., Prester, D. Dominis, Dorner, D., Doro, M., Elsaesser, D., Errando, M., Ferenc, D., Fonseca, M. V., Font, L., López, R. J. García, Garczarczyk, M., Giavitto, G., Godinović, N., Hadasch, D., Herrero, A., Hildebrand, D., Höhne-Mönch, D., Hose, J., Hrupec, D., Jogler, T., Klepser, S., Krähenbühl, T., Kranich, D., Krause, J., La Barbera, A., Leonardo, E., Lindfors, E., Lombardi, S., Longo, F., López, M., Lorenz, E., Majumdar, P., Makariev, M., Maneva, G., Mankuzhiyil, N., Mannheim, K., Maraschi, L., Mariotti, M., Martínez, M., Mazin, D., Meucci, M., Miranda, J. M., Mirzoyan, R., Miyamoto, H., Moldón, J., Moralejo, A., Nieto, D., Nilsson, K., Orito, R., Oya, I., Paoletti, R., Paredes, J. M., Partini, S., Pasanen, M., Pauss, F., Pegna, R. G., Perez-Torres, M. A., Persic, M., Peruzzo, L., Pochon, J., Prada, F., Moroni, P. G. Prada, Prandini, E., Puchades, N., Puljak, I., Reichardt, I., Reinthal, R., Rhode, W., Ribó, M., Rico, J., Rügamer, S., Saggion, A., Saito, K., Saito, T. Y., Salvati, M., Sánchez-Conde, M., Satalecka, K., Scalzotto, V., Scapin, V., Schultz, C., Schweizer, T., Shayduk, M., Shore, S. N., Sierpowska-Bartosik, A., Sillanpää, A., Sitarek, J., Sobczynska, D., Spanier, F., Spiro, S., Stamerra, A., Steinke, B., Storz, J., Strah, N., Struebig, J. C., Suric, T., Takalo, L., Tavecchio, F., Temnikov, P., Terzić, T., Tescaro, D., Teshima, M., Torres, D. F., Vankov, H., Wagner, R. M., Weitzel, Q., Zabalza, V., Zandanel, F., Zanin, R., Neronov, A., Pfrommer, C., Pinzke, A., and Semikoz, D. V.

Subjects
Astrophysics - High Energy Astrophysical Phenomena
Abstract

We report on the detection with the MAGIC telescopes of very high energy gamma-rays from IC 310, a head-tail radio galaxy in the Perseus galaxy cluster, observed during the interval November 2008 to February 2010. The Fermi satellite has also detected this galaxy. The source is detected by MAGIC at a high statistical significance of 7.6sigma in 20.6 hr of stereo data. The observed spectral energy distribution is flat with a differential spectral index of -2.00 \pm 0.14. The mean flux above 300 GeV, between October 2009 and February 2010, (3.1 \pm 0.5)x10^{-12} cm^{-2} s^{-1}, corresponds to (2.5 \pm 0.4)% of Crab Nebula units. Only an upper limit, of 1.9% of Crab Nebula units above 300 GeV, was obtained with the 2008 data. This, together with strong hints (>3sigma) of flares in the middle of October and November 2009, implies that the emission is variable. The MAGIC results favour a scenario with the very high energy emission originating from the inner jet close to the central engine. More complicated models than a simple one-zone SSC scenario, e.g. multi-zone SSC, external Compton or hadronic, may be required to explain the very flat spectrum and its extension over more than three orders of magnitude in energy., Comment: 6 pages, 5 figures, submitted to ApJL

Published
2010
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6. MAGIC Upper Limits for two Milagro-detected, Bright Fermi Sources in the Region of SNR G65.1+0.6

Author

Aleksić, J., Antonelli, L. A., Antoranz, P., Backes, M., Barrio, J. A., Bastieri, D., González, J. Becerra, Bednarek, W., Berdyugin, A., Berger, K., Bernardini, E., Biland, A., Blanch, O., Bock, R. K., Boller, A., Bonnoli, G., Bordas, P., Tridon, D. Borla, Bosch-Ramon, V., Bose, D., Braun, I., Bretz, T., Camara, M., Carmona, E., Carosi, A., Colin, P., Contreras, J. L., Cortina, J., Covino, S., Dazzi, F., De Angelis, A., del Pozo, E. De Cea, De Lotto, B., De Maria, M., De Sabata, F., DelgadoMendez, C., Ortega, A. Diago, Doert, M., Domínguez, A., Prester, D. Dominis, Dorner, D., Doro, M., Elsaesser, D., Errando, M., Ferenc, D., Fonseca, M. V., Font, L., López, R. J. García, Garczarczyk, M., Gaug, M., Giavitto, G., Godinović, N., Hadasch, D., Herrero, A., Hildebrand, D., Höhne-Mönch, D., Hose, J., Hrupec, D., Jogler, T., Klepser, S., Krähenbühl, T., Kranich, D., Krause, J., La Barbera, A., Leonardo, E., Lindfors, E., Lombardi, S., Longo, F., López, M., Lorenz, E., Majumdar, P., Maneva, G., Mankuzhiyil, N., Mannheim, K., Maraschi, L., Mariotti, M., Martínez, M., Mazin, D., Meucci, M., Miranda, J. M., Mirzoyan, R., Miyamoto, H., Moldón, J., Moralejo, A., Nieto, D., Nilsson, K., Orito, R., Oya, I., Paoletti, R., Paredes, J. M., Partini, S., Pasanen, M., Pauss, F., Pegna, R. G., Perez-Torres, M. A., Persic, M., Peruzzo, L., Pochon, J., Prada, F., Moroni, P. G. Prada, Prandini, E., Puchades, N., Puljak, I., Reichardt, I., Reinthal, R., Rhode, W., Ribó, M., Rico, J., Rissi, M., Rügamer, S., Saggion, A., Saito, K., Saito, T. Y., Salvati, M., Sánchez-Conde, M., Satalecka, K., Scalzotto, V., Scapin, V., Schultz, C., Schweizer, T., Shayduk, M., Shore, S. N., Sierpowska-Bartosik, A., Sillanpää, A., Sitarek, J., Sobczynska, D., Spanier, F., Spiro, S., Stamerra, A., Steinke, B., Storz, J., Strah, N., Struebig, J. C., Suric, T., Takalo, L., Tavecchio, F., Temnikov, P., Terzić, T., Tescaro, D., Teshima, M., Torres, D. F., Vankov, H., Wagner, R. M., Weitzel, Q., Zabalza, V., Zandanel, F., and Zanin, R.

Subjects
Astrophysics - High Energy Astrophysical Phenomena
Abstract

We report on the observation of the region around supernova remnant G65.1+0.6 with the stand-alone MAGIC-I telescope. This region hosts the two bright GeV gamma-ray sources 1FGL J1954.3+2836 and 1FGL J1958.6+2845. They are identified as GeV pulsars and both have a possible counterpart detected at about 35 TeV by the Milagro observatory. MAGIC collected 25.5 hours of good quality data, and found no significant emission in the range around 1 TeV. We therefore report differential flux upper limits, assuming the emission to be point-like (<0.1 deg) or within a radius of 0.3 deg. In the point-like scenario, the flux limits around 1 TeV are at the level of 3 % and 2 % of the Crab Nebula flux, for the two sources respectively. This implies that the Milagro emission is either extended over a much larger area than our point spread function, or it must be peaked at energies beyond 1 TeV, resulting in a photon index harder than 2.2 in the TeV band., Comment: 8 pages, 3 figures, 1 table

Published
2010
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7. Magic constraints on Gamma-ray emission from Cygnus X-3

Author

Aleksić, J., Antonelli, L. A., Antoranz, P., Backes, M., Baixeras, C., Barrio, J. A., Bastieri, D., González, J. Becerra, Bednarek, W., Berdyugin, A., Berger, K., Bernardini, E., Biland, A., Blanch, O., Bock, R. K., Boller, A., Bonnoli, G., Bordas, P., Tridon, D. Borla, Bosch-Ramon, V., Bose, D., Braun, I., Bretz, T., Britzger, D., Camara, M., Carmona, E., Carosi, A., Colin, P., Contreras, J. L., Cortina, J., Costado, M. T., Covino, S., Dazzi, F., De Angelis, A., del Pozo, E. De Cea, De Lotto, B., De Maria, M., De Sabata, F., Mendez, C. Delgado, Doert, M., Domínguez, A., Prester, D. Dominis, Dorner, D., Doro, M., Elsaesser, D., Errando, M., Ferenc, D., Fonseca, M. V., Font, L., López, R. J. García, Garczarczyk, M., Gaug, M., Godinovic, N., Göebel, F., Hadasch, D., Herrero, A., Hildebrand, D., Höhne-Mönch, D., Hose, J., Hrupec, D., Hsu, C. C., Jogler, T., Klepser, S., Krähenbühl, T., Kranich, D., La Barbera, A., Laille, A., Leonardo, E., Lindfors, E., Lombardi, S., Longo, F., López, M., Lorenz, E., Majumdar, P., Maneva, G., Mankuzhiyil, N., Mannheim, K., Maraschi, L., Mariotti, M., Martínez, M., Mazin, D., Meucci, M., Miranda, J. M., Mirzoyan, R., Miyamoto, H., Moldón, J., Moles, M., Moralejo, A., Nieto, D., Nilsson, K., Ninkovic, J., Orito, R., Oya, I., Paiano, S., Paoletti, R., Paredes, J. M., Partini, S., Pasanen, M, Pascoli, D., Pauss, F., Pegna, R. G., Perez-Torres, M. A., Persic, M., Peruzzo, L., Prada, F., Prandini, E., Puchades, N., Puljak, I., Reichardt, I., Rhode, W., Ribó, M., Rico, J., Rissi, M, Rügamer, S., Saggion, A., Saito, K., Saito, T. Y., Salvati, M., Sánchez-Conde, M., Satalecka, K., Scalzotto, V., Scapin, V., Schultz, C., Schweizer, T., Shayduk, M., Shore, S. N., Sierpowska-Bartosik, A., Sillanpää, A., Sitarek, J., Sobczynska, D., Spanier, F., Spiro, S., Stamerra, A., Steinke, B., Struebig, J. C., Suric, T., Takalo, L., Tavecchio, F., Temnikov, P., Terzic, T., Tescaro, D., Teshima, M., Torres, D. F., Vankov, H., Wagner, R. M., Weitzel, Q., Zabalza, V., Zandanel, F., Zanin, R., Bulgarelli, A., Max-Moerbeck, W., Piano, G., Pooley, G., Readhead, A. C. S., Richards, J. L., Sabatini, S., Striani, E., Tavani, M., and Trushkin, S.

Subjects
Astrophysics - High Energy Astrophysical Phenomena
Abstract

Cygnus X-3 is a microquasar consisting of an accreting compact object orbiting around a Wolf-Rayet star. It has been detected at radio frequencies and up to high-energy gamma rays (above 100 MeV). However, many models also predict a very high energy (VHE) emission (above hundreds of GeV) when the source displays relativistic persistent jets or transient ejections. Therefore, detecting such emission would improve the understanding of the jet physics. The imaging atmospheric Cherenkov telescope MAGIC observed Cygnus X-3 for about 70 hours between 2006 March and 2009 August in different X-ray/radio spectral states and also during a period of enhanced gamma-ray emission. MAGIC found no evidence for a VHE signal from the direction of the microquasar. An upper limit to the integral flux for energies higher than 250 GeV has been set to 2.2 x 10-12 photons cm-2 s-1 (95% confidence level). This is the best limit so far to the VHE emission from this source. The non-detection of a VHE signal during the period of activity in the high-energy band sheds light on the location of the possible VHE radiation favoring the emission from the innermost region of the jets, where absorption is significant. The current and future generations of Cherenkov telescopes may detect a signal under precise spectral conditions., Comment: 14 pages, 11 figures, This manuscript has been accepted by ApJ (2010)

Published
2010
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8. MAGIC observation of the GRB080430 afterglow

Author

MAGIC Collaboration, Aleksić, J., Anderhub, H., Antonelli, L. A., Antoranz, P., Backes, M., Baixeras, C., Balestra, S., Barrio, J. A., Bastieri, D., González, J. Becerra, Becker, J. K., Bednarek, W., Berdyugin, A., Berger, K., Bernardini, E., Biland, A., Bock, R. K., Bonnoli, G., Bordas, P., Tridon, D. Borla, Bosch-Ramon, V., Bose, D., Braun, I., Bretz, T., Britzger, D., Camara, M., Carmona, E., Carosi, A., Colin, P., Commichau, S., Contreras, J. L., Cortina, J., Costado, M. T., Covino, S., Dazzi, F., De Angelis, A., del Pozo, E. de Cea, Reyes, R. De los, De Lotto, B., De Maria, M., De Sabata, F., Mendez, C. Delgado, Doert, M., Domínguez, A., Prester, D. Dominis, Dorner, D., Doro, M., Elsaesser, D., Errando, M., Ferenc, D., Fernández, E., Firpo, R., Fonseca, M. V., Font, L., Galante, N., López, R. J. García, Garczarczyk, M., Gaug, M., Godinovic, N., Goebel, F., Hadasch, D., Herrero, A., Hildebrand, D., Höhne-Mönch, D., Hose, J., Hrupec, D., Hsu, C. C., Jogler, T., Klepser, S., Krähenbühl, T., Kranich, D., La Barbera, A., Laille, A., Leonardo, E., Lindfors, E., Lombardi, S., Longo, F., López, M., Lorenz, E., Majumdar, P., Maneva, G., Mankuzhiyil, N., Mannheim, K., Maraschi, L., Mariotti, M., Martínez, M., Mazin, D., Meucci, M., Miranda, J. M., Mirzoyan, R., Miyamoto, H., Moldón, J., Moles, M., Moralejo, A., Nieto, D., Nilsson, K., Ninkovic, J., Orito, R., Oya, I., Paoletti, R., Paredes, J. M., Pasanen, M., Pascoli, D., Pauss, F., Pegna, R. G., Perez-Torres, M. A., Persic, M., Peruzzo, L., Prada, F., Prandini, E., Puchades, N., Puljak, I., Reichardt, I., Rhode, W., Ribó, M., Rico, J., Rissi, M., Rügamer, S., Saggion, A., Saito, T. Y., Salvati, M., Sánchez-Conde, M., Satalecka, K., Scalzotto, V., Scapin, V., Schweizer, T., Shayduk, M., Shore, S. N., Sierpowska-Bartosik, A., Sillanpää, A., Sitarek, J., Sobczynska, D., Spanier, F., Spiro, S., Stamerra, A., Steinke, B., Strah, N., Struebig, J. C., Suric, T., Takalo, L., Tavecchio, F., Temnikov, P., Tescaro, D., Teshima, M., Torres, D. F., Turini, N., Vankov, H., Wagner, R. M., Zabalza, V., Zandanel, F., Zanin, R., Zapatero, J., and de Ugarte-Postigo, A.

Subjects
Astrophysics - High Energy Astrophysical Phenomena
Abstract

Context: Gamma-ray bursts are cosmological sources emitting radiation from the gamma-rays to the radio band. Substantial observational efforts have been devoted to the study of gamma-ray bursts during the prompt phase, i.e. the initial burst of high-energy radiation, and during the long-lasting afterglows. In spite of many successes in interpreting these phenomena, there are still several open key questions about the fundamental emission processes, their energetics and the environment. Aim: Independently of specific gamma-ray burst theoretical recipes, spectra in the GeV/TeV range are predicted to be remarkably simple, being satisfactorily modeled with power-laws, and therefore offer a very valuable tool to probe the extragalactic background light distribution. Furthermore, the simple detection of a component at very-high energies, i.e. at $\sim 100$\,GeV, would solve the ambiguity about the importance of various possible emission processes, which provide barely distinguishable scenarios at lower energies. Methods: We used the results of the MAGIC telescope observation of the moderate resdhift ($z\sim0.76$) \object{GRB\,080430} at energies above about 80\,GeV, to evaluate the perspective for late-afterglow observations with ground based GeV/TeV telescopes. Results: We obtained an upper limit of $F_{\rm 95%\,CL} = 5.5 \times 10^{-11}$\,erg\,cm$^{-2}$\,s$^{-1}$ for the very-high energy emission of \object{GRB\,080430}, which cannot set further constraints on the theoretical scenarios proposed for this object also due to the difficulties in modeling the low-energy afterglow. Nonetheless, our observations show that Cherenkov telescopes have already reached the required sensitivity to detect the GeV/TeV emission of GRBs at moderate redshift ($z \lesssim 0.8$), provided the observations are carried out at early times, close to the onset of their afterglow phase., Comment: 6 pages, 1 figure. Astronomy & Astrophysics, in press. Revision affects only the author list.

Published
2010
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9. Search for an extended VHE gamma-ray emission from Mrk 421 and Mrk 501 with the MAGIC Telescope

Author

MAGIC Collaboration, Aleksić, J., Antonelli, L. A., Antoranz, P., Backes, M., Baixeras, C., Barrio, J. A., Bastieri, D., González, J. Becerra, Bednarek, W., Berdyugin, A., Berger, K., Bernardini, E., Biland, A., Blanch, O., Bock, R. K., Bonnoli, G., Bordas, P., Tridon, D. Borla, Bosch-Ramon, V., Bose, D., Braun, I., Bretz, T., Britzger, D., Camara, M., Carmona, E., Carosi, A., Colin, P., Commichau, S., Contreras, J. L., Cortina, J., Costado, M. T., Covino, S., Dazzi, F., De Angelis, A., del Pozo, E. De Cea, Reyes, R. De los, De Lotto, B., De Maria, M., De Sabata, F., Mendez, C. Delgado, Doert, M., Domínguez, A., Prester, D. Dominis, Dorner, D., Doro, M., Elsaesser, D., Errando, M., Ferenc, D., Fonseca, M. V., Font, L., López, R. J. García, Garczarczyk, M., Gaug, M., Godinovic, N., Hadasch, D., Herrero, A., Hildebrand, D., Höhne-Mönch, D., Hose, J., Hrupec, D., Hsu, C. C., Jogler, T., Klepser, S., Krähenbühl, T., Kranich, D., La Barbera, A., Laille, A., Leonardo, E., Lindfors, E., Lombardi, S., Longo, F., López, M., Lorenz, E., Majumdar, P., Maneva, G., Mankuzhiyil, N., Mannheim, K., Maraschi, L., Mariotti, M., Martínez, M., Mazin, D., Meucci, M., Miranda, J. M., Mirzoyan, R., Miyamoto, H., Moldón, J., Moles, M., Moralejo, A., Nieto, D., Nilsson, K., Ninkovic, J., Orito, R., Oya, I., Paiano, S., Paoletti, R., Paredes, J. M., Partini, S., Pasanen, M., Pascoli, D., Pauss, F., Pegna, R. G., Perez-Torres, M. A., Persic, M., Peruzzo, L., Prada, F., Prandini, E., Puchades, N., Puljak, I., Reichardt, I., Rhode, W., Ribó, M., Rico, J., Rissi, M., Rügamer, S., Saggion, A., Saito, T. Y., Salvati, M., Sánchez-Conde, M., Satalecka, K., Scalzotto, V., Scapin, V., Schultz, C., Schweizer, T., Shayduk, M., Shore, S. N., Sierpowska-Bartosik, A., Sillanpää, A., Sitarek, J., Sobczynska, D., Spanier, F., Spiro, S., Stamerra, A., Steinke, B., Struebig, J. C., Suric, T., Takalo, L., Tavecchio, F., Temnikov, P., Terzic, T., Tescaro, D., Teshima, M., Torres, D. F., Vankov, H., Wagner, R. M., Weitzel, Q., Zabalza, V., Zandanel, F., Zanin, R., Neronov, A., and Semikoz, D. V.

Subjects
Astrophysics - High Energy Astrophysical Phenomena
Abstract

Context: Part of the very high energy $\gamma$-ray radiation coming from extragalactic sources is absorbed through the pair production process on the extragalactic background light photons. Extragalactic magnetic fields alter the trajectories of these cascade pairs and, in turn, convert cosmic background photons to gamma-ray energies by inverse Compton scattering. These secondary photons can form an extended halo around bright VHE sources. Aims: We searched for an extended emission around the bright blazars Mrk 421 and Mrk 501 using the MAGIC telescope data. Methods: If extended emission is present, the angular distribution of reconstructed gamma-ray arrival directions around the source is broader than for a point-like source. In the analysis of a few tens of hours of observational data taken from Mrk 421 and Mrk 501 we used a newly developed method that provides better angular resolution. This method is based on the usage of multidimensional decision trees. Comparing the measured shapes of angular distributions with those expected from a point-like source one can detect or constrain possible extended emission around the source. We also studied the influence of different types of systematic errors on the shape of the distribution of reconstructed gamma-ray arrival directions for a point source. Results: We present upper limits for an extended emission calculated for both sources for various source extensions and emission profiles. We discuss possible constraints on the extragalactic magnetic fields strength. We obtain upper limits on the extended emission around the Mrk~421 (Mrk~501) on the level of < 5% (< 4%) of the Crab Nebula flux above the energy threshold of 300 GeV. Using these results we discuss possible constraints on the extragalactic magnetic fields strength around a few times $10^{-15}$~G., Comment: 8 pages, 9 figures, accepted for publication in A&A

Published
2010
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10. Gamma-ray excess from a stacked sample of high- and intermediate-frequency peaked blazars observed with the MAGIC telescope

Author

MAGIC Collaboration, Aleksić, J., Antonelli, L. A., Antoranz, P., Backes, M., Baixeras, C., Barrio, J. A., Bastieri, D., González, J. Becerra, Bednarek, W., Berdyugin, A., Berger, K., Bernardini, E., Biland, A., Blanch, O., Bock, R. K., Bonnoli, G., Bordas, P., Tridon, D. Borla, Bosch-Ramon, V., Bose, D., Braun, I., Bretz, T., Britzger, D., Camara, M., Carmona, E., Carosi, A., Colin, P., Commichau, S., Contreras, J. L., Cortina, J., Costado, M. T., Covino, S., Dazzi, F., De Angelis, A., del Pozo, E. De Cea, Reyes, R. De los, De Lotto, B., De Maria, M., De Sabata, F., Mendez, C. Delgado, Doert, M., Domínguez, A., Prester, D. Dominis, Dorner, D., Doro, M., Elsaesser, D., Errando, M., Ferenc, D., Fonseca, M. V., Font, L., López, R. J. García, Garczarczyk, M., Gaug, M., Godinovic, N., Hadasch, D., Herrero, A., Hildebrand, D., Höhne-Mönch, D., Hose, J., Hrupec, D., Hsu, C. C., Jogler, T., Klepser, S., Krähenbühl, T., Kranich, D., La Barbera, A., Laille, A., Leonardo, E., Lindfors, E., Lombardi, S., Longo, F., López, M., Lorenz, E, Majumdar, P., Maneva, G., Mankuzhiyil, N., Mannheim, K., Maraschi, L., Mariotti, M., Martínez, M., Mazin, D., Meucci, M., Miranda, J. M., Mirzoyan, R., Miyamoto, H., Moldón, J., Moles, M., Moralejo, A., Nieto, D., Nilsson, K., Ninkovic, J., Orito, R., Oya, I., Paiano, S., Paoletti, R., Paredes, J. M., Partini, S., Pasanen, M., Pascoli, D., Pauss, F., Pegna, R. G., Perez-Torres, M. A., Persic, M., Peruzzo, L., Prada, F., Prandini, E., Puchades, N., Puljak, I., Reichardt, I., Rhode, W., Ribó, M., Rico, J., Rissi, M., Rügamer, S., Saggion, A., Saito, T. Y., Salvati, M., Sánchez-Conde, M., Satalecka, K., Scalzotto, V., Scapin, V., Schultz, C., Schweizer, T., Shayduk, M., Shore, S. N., Sierpowska-Bartosik, A., Sillanpää, A., Sitarek, J, Sobczynska, D., Spanier, F., Spiro, S., Stamerra, A., Steinke, B., Struebig, J. C., Suric, T., Takalo, L., Tavecchio, F., Temnikov, P., Terzic, T., Tescaro, D., Teshima, M., Tibolla, O., Torres, D. F., Vankov, H., Wagner, R. M., Weitzel, Q., Zabalza, V, Zandanel, F., and Zanin, R.

Subjects
Astrophysics - High Energy Astrophysical Phenomena
Abstract

Between 2004 and 2009 a sample of 28 X-ray selected high- and intermediate-frequency peaked blazars with a X-ray flux larger than 2 uJy at 1 keV in the redshift range from 0.018 to 0.361 was observed with the MAGIC telescope at energies above 100 GeV. Seven among them were detected and the results of these observations are discussed elsewhere. Here we concentrate on the remaining 21 blazars which were not detected during this observation campaign and present the 3 sigma (99.7 %) confidence upper limits on their flux. The individual flux upper limits lie between 1.6 % and 13.6 % of the integral flux from the Crab Nebula. Applying a stacking method to the sample of non-detections with a total of 394.1 hours exposure time, we find evidence for an excess with a cumulative significance of 4.9 standard deviations. It is not dominated by individual objects or flares, but increases linearly with the observation time as for a constant source with an integral flux level of ~1.5 % of that observed from the Crab Nebula above 150 GeV., Comment: 14 pages, 6 figures, accepted by ApJ

Published
2010
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11. MAGIC TeV Gamma-Ray Observations of Markarian 421 during Multiwavelength Campaigns in 2006

Author

MAGIC Collaboration, Aleksić, J., Antonelli, L. A., Antoranz, P., Backes, M., Baixeras, C., Balestra, S., Barrio, J. A., Bastieri, D., González, J. Becerra, Bednarek, W., Berdyugin, A., Berger, K., Bernardini, E., Biland, A., Bock, R. K., Bonnoli, G., Bordas, P., Tridon, D. Borla, Bosch-Ramon, V., Bose, D., Braun, I., Bretz, T., Britzger, D., Camara, M., Carmona, E., Carosi, A., Colin, P., Commichau, S., Contreras, J. L., Cortina, J., Costado, M. T., Covino, S., Dazzi, F., De Angelis, A., del Pozo, E. De Cea, Mendez, C. Delgado, Reyes, R. De los, De Lotto, B., De Maria, M., De Sabata, F., Doert, M., Domínguez, A., Prester, D. Dominis, Dorner, D., Doro, M., Elsaesser, D., Errando, M., Ferenc, D., Fonseca, M. V., Font, L., López, R. J. García, Garczarczyk, M., Gaug, M., Godinovic, N., Hadasch, D., Herrero, A., Hildebrand, D., Höhne-Mönch, D., Hose, J., Hrupec, D., Hsu, C. C., Jogler, T., Klepser, S., Krähenbühl, T., Kranich, D., La Barbera, A., Laille, A., Leonardo, E., Lindfors, E., Lombardi, S., Longo, F., López, M., Lorenz, E., Majumdar, P., Maneva, G., Mankuzhiyil, N., Mannheim, K., Maraschi, L., Mariotti, M., Martínez, M., Mazin, D., Meucci, M., Miranda, J. M., Mirzoyan, R., Miyamoto, H., Moldón, J., Moles, M., Moralejo, A., Nieto, D., Nilsson, K., Ninkovic, J., Orito, R., Oya, I., Paiano, S., Paoletti, R., Paredes, J. M., Partini, S., Pasanen, M., Pascoli, D., Pauss, F., Pegna, R. G., Perez-Torres, M. A., Persic, M., Peruzzo, L., Prada, F., Prandini, E., Puchades, N., Puljak, I., Reichardt, I., Rhode, W., Ribó, M., Rico, J., Rissi, M., Rügamer, S., Saggion, A., Saito, T. Y., Salvati, M., Sánchez-Conde, M., Satalecka, K., Scalzotto, V., Scapin, V., Schultz, C., Schweizer, T., Shayduk, M., Shore, S. N., Sierpowska-Bartosik, A., Sillanpää, A., Sitarek, J., Sobczynska, D., Spanier, F., Spiro, S., Stamerra, A., Steinke, B., Struebig, J. C., Suric, T., Takalo, L., Tavecchio, F., Temnikov, P., Terzic, T., Tescaro, D., Teshima, M., Torres, D. F., Vankov, H., Wagner, R. M., Zabalza, V., Zandanel, F., and Zanin, R.

Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

The Major Atmospheric Gamma Imaging Cerenkov (MAGIC) telescope participated in three multiwavelength (MWL) campaigns, observing the blazar Markarian (Mkn) 421 during the nights of 2006 April 28, 29, and 2006 June 14. We analyzed the corresponding MAGIC very-high energy observations during 9 nights from 2006 April 22 to 30 and on 2006 June 14. We inferred light curves with sub-day resolution and night-by-night energy spectra. A strong gamma-ray signal was detected from Mkn 421 on all observation nights. The flux (E > 250 GeV) varied on night-by-night basis between (0.92+-0.11)10^-10 cm^-2 s^-1 (0.57 Crab units) and (3.21+-0.15)10^-10 cm^-2 s^-1 (2.0 Crab units) in 2006 April. There is a clear indication for intra-night variability with a doubling time of 36+-10(stat) minutes on the night of 2006 April 29, establishing once more rapid flux variability for this object. For all individual nights gamma-ray spectra could be inferred, with power-law indices ranging from 1.66 to 2.47. We did not find statistically significant correlations between the spectral index and the flux state for individual nights. During the June 2006 campaign, a flux substantially lower than the one measured by the Whipple 10-m telescope four days later was found. Using a log-parabolic power law fit we deduced for some data sets the location of the spectral peak in the very-high energy regime. Our results confirm the indications of rising peak energy with increasing flux, as expected in leptonic acceleration models., Comment: 11 pages, 7 figures, accepted for publication by Astron. Astrophys

Published
2010
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12. Simultaneous multi-frequency observation of the unknown redshift blazar PG 1553+113 in March-April 2008

Author

MAGIC Collaboration, Aleksić, J., Anderhub, H., Antonelli, L. A., Antoranz, P., Backes, M., Baixeras, C., Balestra, S., Barrio, J. A., Bastieri, D., González, J. Becerra, Becker, J. K., Bednarek, W., Berdyugin, A., Berger, K., Bernardini, E., Biland, A., Bock, R. K., Bonnoli, G., Bordas, P., Tridon, D. Borla, Bosch-Ramon, V., Bose, D., Braun, I., Bretz, T., Britzger, D., Camara, M., Carmona, E., Carosi, A., Colin, P., Commichau, S., Contreras, J. L., Cortina, J., Costado, M. T., Covino, S., Dazzi, F., De Angelis, A., del Pozo, E. de Cea, Reyes, R. De los, De Lotto, B., De Maria, M., De Sabata, F., Mendez, C. Delgado, Domínguez, A., Prester, D. Dominis, Dorner, D., Doro, M., Elsaesser, D., Errando, M., Ferenc, D., Fernández, E., Firpo, R., Fonseca, M. V., Font, L., Galante, N., López, R. J. García, Garczarczyk, M., Gaug, M., Godinovic, N., Goebel, F., Hadasch, D., Herrero, A., Hildebrand, D., Höhne-Mönch, D., Hose, J., Hrupec, D., Hsu, C. C., Jogler, T., Klepser, S., Krähenbühl, T., Kranich, D., La Barbera, A., Laille, A., Leonardo, E., Lindfors, E., Lombardi, S., Longo, F., López, M., Lorenz, E., Majumdar, P., Maneva, G., Mankuzhiyil, N., Mannheim, K., Maraschi, L., Mariotti, M., Martínez, M., Mazin, D., Meucci, M., Miranda, J. M., Mirzoyan, R., Miyamoto, H., Moldón, J., Moles, M., Moralejo, A., Nieto, D., Nilsson, K., Ninkovic, J., Orito, R., Oya, I., Paoletti, R., Paredes, J. M., Pasanen, M., Pascoli, D., Pauss, F., Pegna, R. G., Perez-Torres, M. A., Persic, M., Peruzzo, L., Prada, F., Prandini, E., Puchades, N., Puljak, I., Reichardt, I., Rhode, W., Ribó, M., Rico, J., Rissi, M., Rügamer, S., Saggion, A., Saito, T. Y., Salvati, M., Sánchez-Conde, M., Satalecka, K., Scalzotto, V., Scapin, V., Schweizer, T., Shayduk, M., Shore, S. N., Sierpowska-Bartosik, A., Sillanpää, A., Sitarek, J., Sobczynska, D., Spanier, F., Spiro, S., Stamerra, A., Steinke, B., Strah, N., Struebig, J. C., Suric, T., Takalo, L., Tavecchio, F., Temnikov, P., Tescaro, D., Teshima, M., Torres, D. F., Turini, N., Vankov, H., Wagner, R. M., Zabalza, V., Zandanel, F., Zanin, R., Zapatero, J., Pian, E., Bianchin, V., D'Ammando, F., Di Cocco, G., Fugazza, D., Ghisellini, G., Kurtanidze, O. M., Raiteri, C. M., Tosti, G., Treves, A., Vercellone, S., and Villata, M.

Subjects
Astrophysics - High Energy Astrophysical Phenomena, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

The blazar PG 1553+113 is a well known TeV gamma-ray emitter. In this paper, we determine its spectral energy distribution using simultaneous multi-frequency data in order to study its emission processes. An extensive campaign was carried out between March and April 2008, where optical, X-ray, high-energy (HE) gamma-ray, and very-high-energy (VHE) gamma-ray data were obtained with the KVA, Abastumani, REM, RossiXTE/ASM, AGILE and MAGIC telescopes, respectively. This is the first simultaneous broad-band (i.e., HE+VHE) gamma-ray observation, though AGILE did not detect the source. We combine data to derive source's spectral energy distribution and interpret its double peaked shape within the framework of a synchrotron self compton model, Comment: 5 pages, 2 figures, published

Published
2009
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13. Correlated X-ray and Very High Energy emission in the gamma-ray binary LS I +61 303

Author

The MAGIC Collaboration, Anderhub, H., Antonelli, L. A., Antoranz, P., Backes, M., Baixeras, C., Balestra, S., Barrio, J. A., Bastieri, D., González, J. Becerra, Becker, J. K., Bednarek, W., Berger, K., Bernardini, E., Biland, A., Bigas, O. Blanch, Bock, R. K., Bonnoli, G., Bordas, P., Tridon, D. Borla, Bosch-Ramon, V., Bose, D., Braun, I., Bretz, T., Britzger, D., Camara, M., Carmona, E., Carosi, A., Colin, P., Commichau, S., Contreras, J. L., Cortina, J., Costado, M. T., Covino, S., Dazzi, F., De Angelis, A., del Pozo, E. de Cea, Reyes, R. De los, De Lotto, B., De Maria, M., De Sabata, F., Mendez, C. Delgado, Domínguez, A., Prester, D. Dominis, Dorner, D., Doro, M., Elsaesser, D., Errando, M., Ferenc, D., Fernández, E., Firpo, R., Fonseca, M. V., Font, L., Galante, N., López, R. J. García, Garczarczyk, M., Gaug, M., Godinovic, N., Goebel, F., Hadasch, D., Herrero, A., Hildebrand, D., Höhne-Mönch, D., Hose, J., Hrupec, D., Hsu, C. C., Jogler, T., Klepser, S., Kranich, D., La Barbera, A., Laille, A., Leonardo, E., Lindfors, E., Lombardi, S., Longo, F., López, M., Lorenz, E., Majumdar, P., Maneva, G., Mankuzhiyil, N., Mannheim, K., Maraschi, L., Mariotti, M., Martínez, M., Mazin, D., Meucci, M., Miranda, J. M., Mirzoyan, R., Miyamoto, H., Moldón, J., Moles, M., Moralejo, A., Nieto, D., Nilsson, K., Ninkovic, J., Orito, R., Oya, I., Paoletti, R., Paredes, J. M., Pasanen, M., Pascoli, D., Pauss, F., Pegna, R. G., Perez-Torres, M. A., Persic, M., Peruzzo, L., Prada, F., Prandini, E., Puchades, N., Puljak, I., Reichardt, I., Rhode, W., Ribó, M., Rico, J., Rissi, M., Robert, A., Rügamer, S., Saggion, A., Saito, T. Y., Salvati, M., Sánchez-Conde, M., Satalecka, K., Scalzotto, V., Scapin, V., Schweizer, T., Shayduk, M., Shore, S. N., Sidro, N., Sierpowska-Bartosik, A., Sillanpää, A., Sitarek, J., Sobczynska, D., Spanier, F., Spiro, S., Stamerra, A., Stark, L. S., Suric, T., Takalo, L., Tavecchio, F., Temnikov, P., Tescaro, D., Teshima, M., Torres, D. F., Turini, N., Vankov, H., Wagner, R. M., Zabalza, V., Zandanel, F., Zanin, R., Zapatero, J., Falcone, A., Vetere, L., Gehrels, N., Trushkin, S., Dhawan, V., and Reig, P.

Subjects
Astrophysics - High Energy Astrophysical Phenomena
Abstract

The discovery of very high energy (VHE) gamma-ray emitting X-ray binaries has triggered an intense effort to better understand the particle acceleration, absorption, and emission mechanisms in compact binary systems, which provide variable conditions along eccentric orbits. Despite this, the nature of some of these systems, and of the accelerated particles producing the VHE emission, is unclear. To answer some of these open questions, we conducted a multiwavelength campaign of the VHE gamma-ray emitting X-ray binary LS I +61 303 including the MAGIC telescope, XMM-Newton, and Swift during 60% of an orbit in 2007 September. We detect a simultaneous outburst at X-ray and VHE bands, with the peak at phase 0.62 and a similar shape at both wavelengths. A linear fit to the simultaneous X-ray/VHE pairs obtained during the outburst yields a correlation coefficient of r=0.97, while a linear fit to all simultaneous pairs provides r=0.81. Since a variable absorption of the VHE emission towards the observer is not expected for the data reported here, the correlation found indicates a simultaneity in the emission processes. Assuming that they are dominated by a single particle population, either hadronic or leptonic, the X-ray/VHE flux ratio favors leptonic models. This fact, together with the detected photon indices, suggests that in LS I +61 303 the X-rays are the result of synchrotron radiation of the same electrons that produce VHE emission as a result of inverse Compton scattering of stellar photons., Comment: To appear in The Astrophysical Journal Letters. 6 pages, 2 figures

Published
2009
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14. MAGIC Gamma-ray Telescope Observation of the Perseus Cluster of Galaxies: implications for cosmic rays, dark matter, and NGC1275

Author

The MAGIC Collaboration, Aleksić, J., Antonelli, L. A., Antoranz, P., Backes, M., Baixeras, C., Balestra, S., Barrio, J. A., Bastieri, D., González, J. Becerra, Bednarek, W., Berdyugin, A., Berger, K., Bernardini, E., Biland, A., Bock, R. K., Bonnoli, G., Bordas, P., Tridon, D. Borla, Bosch-Ramon, V., Bose, D., Braun, I., Bretz, T., Britzger, D., Camara, M., Carmona, E., Carosi, A., Colin, P., Commichau, S., Contreras, J. L., Cortina, J., Costado, M. T., Covino, S., Dazzi, F., De Angelis, A., del Pozo, E. De Cea, Reyes, R. De los, De Lotto, B., De Maria, M., De Sabata, F., Mendez, C. Delgado, Doert, M., Domínguez, A., Prester, D. Dominis, Dorner, D., Doro, M., Elsaesser, D., Errando, M., Ferenc, D., Fonseca, M. V., Font, L., Galante, N., López, R. J. García, Garczarczyk, M., Gaug, M., Godinovic, N., Hadasch, D., Herrero, A., Hildebrand, D., Höhne-Mönch, D., Hose, J., Hrupec, D., Hsu, C. C., Jogler, T., Klepser, S., Krähenbühl, T., Kranich, D., La Barbera, A., Laille, A., Leonardo, E., Lindfors, E., Lombardi, S., Longo, F., López, M., Lorenz, E., Majumdar, P., Maneva, G., Mankuzhiyil, N., Mannheim, K., Maraschi, L., Mariotti, M., Martínez, M., Mazin, D., Meucci, M., Miranda, J. M., Mirzoyan, R., Miyamoto, H., Moldón, J., Moles, M., Moralejo, A., Nieto, D., Nilsson, K., Ninkovic, J., Orito, R., Oya, I., Paiano, S., Paoletti, R., Paredes, J. M., Partini, S., Pasanen, M., Pascoli, D., Pauss, F., Pegna, R. G., Perez-Torres, M. A., Persic, M., Peruzzo, L., Prada, F., Prandini, E., Puchades, N., Puljak, I., Reichardt, I., Rhode, W., Ribó, M., Rico, J., Rissi, M., Rügamer, S., Saggion, A., Saito, T. Y., Salvati, M., Sánchez-Conde, M., Satalecka, K., Scalzotto, V., Scapin, V., Schultz, C., Schweizer, T., Shayduk, M., Shore, S. N., Sierpowska-Bartosik, A., Sillanpää, A., Sitarek, J., Sobczynska, D., Spanier, F., Spiro, S., Stamerra, A., Steinke, B., Struebig, J. C., Suric, T., Takalo, L., Tavecchio, F., Temnikov, P., Terzic, T., Tescaro, D., Teshima, M., Torres, D. F., Vankov, H., Wagner, R. M., Zabalza, V., Zandanel, F., Zanin, R., Zapatero, J., Pfrommer, C., Pinzke, A., Enßlin, T. A., Inoue, S., and Ghisellini, G.

Subjects
Astrophysics - High Energy Astrophysical Phenomena
Abstract

The Perseus galaxy cluster was observed by the MAGIC Cherenkov telescope for a total effective time of 24.4 hr during 2008 November and December. The resulting upper limits on the gamma-ray emission above 100 GeV are in the range of 4.6 to 7.5 x 10^{-12} cm^{-2} s^{-1} for spectral indices from -1.5 to -2.5, thereby constraining the emission produced by cosmic rays, dark matter annihilations, and the central radio galaxy NGC1275. Results are compatible with cosmological cluster simulations for the cosmic-ray-induced gamma-ray emission, constraining the average cosmic ray-to-thermal pressure to <4% for the cluster core region (<8% for the entire cluster). Using simplified assumptions adopted in earlier work (a power-law spectrum with an index of -2.1, constant cosmic ray-to-thermal pressure for the peripheral cluster regions while accounting for the adiabatic contraction during the cooling flow formation), we would limit the ratio of cosmic ray-to-thermal energy to E_CR/E_th<3%. The upper limit also translates into a level of gamma-ray emission from possible annihilations of the cluster dark matter (the dominant mass component) that is consistent with boost factors of ~10^4 for the typically expected dark matter annihilation-induced emission. Finally, the upper limits obtained for the gamma-ray emission of the central radio galaxy NGC1275 are consistent with the recent detection by the Fermi-LAT satellite. Due to the extremely large Doppler factors required for the jet, a one-zone synchrotron self-Compton model is implausible in this case. We reproduce the observed spectral energy density by using the structured jet (spine-layer) model which has previously been adopted to explain the high-energy emission of radio galaxies., Comment: 15 pages, 5 figures; accepted for publication in ApJ; updated to match the journal final version

Published
2009
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15. MAGIC Collaboration: Contributions to the 31st International Cosmic Ray Conference (ICRC 2009)

Author

The MAGIC Collaboration, Anderhub, H., Antonelli, L. A., Antoranz, P., Backes, M., Baixeras, C., Balestra, S., Barrio, J. A., Bastieri, D., González, J. Becerra, Becker, J. K., Bednarek, W., Berger, K., Bernardini, E., Biland, A., Bock, R. K., Bonnoli, G., Bordas, P., Tridon, D. Borla, Bosch-Ramon, V., Bose, D., Braun, I., Bretz, T., Britzger, D., Camara, M., Carmona, E., Carosi, A., Colin, P., Commichau, S., Contreras, J. L., Cortina, J., Costado, M. T., Covino, S., Dazzi, F., De Angelis, A., del Pozo, E. de Cea, Mendez, C. Delgado, Reyes, R. De los, De Lotto, B., De Maria, M., De Sabata, F., Domínguez, A., Prester, D. Dominis, Dorner, D., Doro, M., Elsaesser, D., Errando, M., Ferenc, D., Fernández, E., Firpo, R., Fonseca, M. V., Font, L., Galante, N., López, R. J. García, Garczarczyk, M., Gaug, M., Godinovic, N., Goebel, F., Hadasch, D., Herrero, A., Hildebrand, D., Höhne-Mönch, D., Hose, J., Hrupec, D., Hsu, C. C., Jogler, T., Klepser, S., Kranich, D., La Barbera, A., Laille, A., Leonardo, E., Lindfors, E., Lombardi, S., Longo, F., López, M., Lorenz, E., Majumdar, P., Maneva, G., Mankuzhiyil, N., Mannheim, K., Maraschi, L., Mariotti, M., Martínez, M., Mazin, D., Meucci, M., Miranda, J. M., Mirzoyan, R., Miyamoto, H., Moldón, J., Moles, M., Moralejo, A., Nieto, D., Nilsson, K., Ninkovic, J., Orito, R., Oya, I., Paoletti, R., Paredes, J. M., Pasanen, M., Pascoli, D., Pauss, F., Pegna, R. G., Perez-Torres, M. A., Persic, M., Peruzzo, L., Prada, F., Prandini, E., Puchades, N., Puljak, I., Reichardt, I., Rhode, W., Ribó, M., Rico, J., Rissi, M., Robert, A., Rügamer, S., Saggion, A., Saito, T. Y., Salvati, M., Sánchez-Conde, M., Satalecka, K., Scalzotto, V., Scapin, V., Schweizer, T., Shayduk, M., Shore, S. N., Sierpowska-Bartosik, A., Sillanpää, A., Sitarek, J., Sobczynska, D., Spanier, F., Spiro, S., Stamerra, A., Stark, L. S., Suric, T., Takalo, L., Tavecchio, F., Temnikov, P., Tescaro, D., Teshima, M., Torres, D. F., Turini, N., Vankov, H., Wagner, R. M., Zabalza, V., Zandanel, F., Zanin, R., and Zapatero, J.

Subjects
Astrophysics - High Energy Astrophysical Phenomena, Astrophysics - Cosmology and Extragalactic Astrophysics, Astrophysics - Instrumentation and Methods for Astrophysics
Abstract

Index entry listing the contributed papers of the MAGIC collaboration to the 31th International Cosmic Ray Conference (ICRC 2009), July 7-15 2009, \L\'od\'z, Poland. The individual papers are sorted by subject: Overview and Highlight Papers; MAGIC-II Status and Components; Software and Analysis Techniques; Technical Developments; Scientific Results. This HTML document includes clickable links to the papers that exist on the astro-ph arXiv. We hope that this will make it easy to access the MAGIC contributions in a systematic way., Comment: Index of the MAGIC conference proceedings for ICRC 2009. Added 6 papers missing in v1

Published
2009

16. A novel background reduction strategy for high level triggers and processing in gamma-ray Cherenkov detectors

Author

Cabras, G., De Angelis, A., De Lotto, B., De Maria, M. M., De Sabata, F., Mansutti, O., Frailis, M., Persic, M., Bigongiari, C., Doro, M., Mariotti, M., Peruzzo, L., Saggion, A., Scalzotto, V., Paoletti, R., Scribano, A., Turini, N., Moralejo, A., Tescaro, D., and Collaboration, the MAGIC

Subjects
Astrophysics
Abstract

Gamma ray astronomy is now at the leading edge for studies related both to fundamental physics and astrophysics. The sensitivity of gamma detectors is limited by the huge amount of background, constituted by hadronic cosmic rays (typically two to three orders of magnitude more than the signal) and by the accidental background in the detectors. By using the information on the temporal evolution of the Cherenkov light, the background can be reduced. We will present here the results obtained within the MAGIC experiment using a new technique for the reduction of the background. Particle showers produced by gamma rays show a different temporal distribution with respect to showers produced by hadrons; the background due to accidental counts shows no dependence on time. Such novel strategy can increase the sensitivity of present instruments., Comment: 4 pages, 3 figures, Proc. of the 9th Int. Syposium "Frontiers of Fundamental and Computational Physics" (FFP9), (AIP, Melville, New York, 2008, in press)

Published
2008
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17. The MAGIC Project: Contributions to ICRC 2007

Author

Albert, J., Aliu, E., Anderhub, H., Antoranz, P., Armada, A., Baixeras, C., Barrio, J. A., Bartko, H., Bastieri, D., Becker, J. K., Bednarek, W., Berger, K., Bigongiari, C., Biland, A., Bock, R. K., Bordas, P., Bosch-Ramon, V., Bretz, T., Britvitch, I., Cabras, G., Camara, M., Carmona, E., Chilingarian, A., Coarasa, J. A., Commichau, S., Contreras, J. L., Cortina, J., Costado, M. T., Curtef, V., Danielyan, V., Dazzi, F., De Angelis, A., Delgado, C., Reyes, R. de los, De Lotto, B., De Maria, M., De Sabata, F., Dorner, D., Doro, M., Errando, M., Fagiolini, M., Ferenc, D., Fernández, E., Firpo, R., Flix, J., Fonseca, M. V., Font, L., Fuchs, M., Galante, N., García-López, R. J., Garczarczyk, M., Gaug, M., Giller, M., Goebel, F., Hakobyan, D., Hayashida, M., Hengstebeck, T., Herrero, A., Höhne, D., Hose, J., Hsu, C. C., Jacon, P., Jogler, T., Kosyra, R., Kranich, D., Kritzer, R., Laille, A., Lindfors, E., Lombardi, S., Longo, F., López, J., López, M., Lorenz, E., Majumdar, P., Maneva, G., Mannheim, K., Mansutti, O., Mariotti, M., Martínez, M., Mazin, D., Merck, C., Meucci, M., Meyer, M., Miranda, J. M., Mirzoyan, R., Mizobuchi, S., Moralejo, A., Nieto, D., Nilsson, K., Ninkovic, J., na-Wilhelmi, E. O, Otte, N., Oya, I., Paneque, D., Paoletti, R., Paredes, J. M., Pasanen, M., Pascoli, D., Pauss, F., Pegna, R., Persic, M., Peruzzo, L., Piccioli, A., Prandini, E., Puchades, N., Raymers, A., Rhode, W., Ribó, M., Rico, J., Rissi, M., Robert, A., Rügamer, S., Saggion, A., Saito, T. Y., Sánchez, A., Sartori, P., Scalzotto, V., Scapin, V., Schmitt, R., Schweizer, T., Shayduk, M., Shinozaki, K., Shore, S. N., Sidro, N., Sillanpää, A., Sobczynska, D., Spanier, F., Stamerra, A., Stark, L. S., Takalo, L., Temnikov, P., Tescaro, D., Teshima, M., Torres, D. F., Turini, N., Vankov, H., Venturini, A., Vitale, V., Wagner, R. M., Wibig, T., Wittek, W., Zandanel, F., Zanin, R., and Zapatero, J.

Subjects
Astrophysics
Abstract

The MAGIC Project: Contributions to ICRC 2007, Merida, Mexico. Contents pages for the Contribution on behalf of the MAGIC Collaboration to the 30th ICRC that took place in July 2007 in Merida, Mexico. The contents are in html form with clickable links to the papers that exist on the Astrophysics archive. We hope that this will make it easier to access the output of the conference in a systematic way. Comments on how useful this is/ how it could be improved should be sent to michela.demaria@iuav.it., Comment: HTML file with clickable links to papers

Published
2007

18. Monte Carlo Simulation for the MAGIC-II System

Author

Carmona, E., Majumdar, P., Moralejo, A., Vitale, V., Sobczynska, D., Haffke, M., Bigongiari, C., Otte, N., Cabras, G., De Maria, M., and De Sabata, F.

Subjects
Astrophysics
Abstract

Within the year 2007, MAGIC will be upgraded to a two telescope system at La Palma. Its main goal is to improve the sensitivity in the stereoscopic/coincident operational mode. At the same time it will lower the analysis threshold of the currently running single MAGIC telescope. Results from the Monte Carlo simulations of this system will be discussed. A comparison of the two telescope system with the performance of one single telescope will be shown in terms of sensitivity, angular resolution and energy resolution., Comment: 4 pages, 5 figures, Contribution to the 30th ICRC, Merida, Mexico, July 2007 on behalf of the MAGIC Collaboration

Published
2007

19. Influence of Temperature and Precipitation Anomaly on the Seasonal Emergence of Invasive Bark Beetles in Subtropical South America

Author

Gomez, D. F., Skelton, J., De María, M., and Hulcr, J.

Abstract

Several invasive bark beetle species have caused major economic and ecological losses in South America. Accurate predictions of beetle emergence times will make control efforts more efficient and effective. To determine whether bark beetle emergence can be predicted by season, temperature, or precipitation, we analyzed trapping records for three introduced pest species of bark beetles in Uruguay. We used trigonometric functions as seasonal predictors in generalized linear models to account for purely seasonal effects, while testing for effects of temperature and precipitation. Results show that all three beetle species had strong but unique seasonal emergence patterns and responded differently to temperature and precipitation. Cyrtogenius luteus(Blandford) emerged in summer and increased with precipitation but was not affected by temperature. Hylurgus ligniperda(Fabricius) emerged in winter and increased with temperature but was not affected by precipitation. Orthotomicus erosus(Wollaston) had a primary emergence in spring, and a smaller emergence in early summer, but showed no significant relationship with temperature or precipitation. This study shows that the emergence of these bark beetle species in Uruguay is influenced by seasonality more than by temperature and precipitation fluctuations. It also shows how seasonality can be easily incorporated into models to make more accurate predictions about pest population dynamics.

Published
2024
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22. Improving the performance of the single-dish Cherenkov telescope MAGIC through the use of signal timing

Author

Aliu, E., Anderhub, H., Antonelli, L.A., Antoranz, P., Backes, M., Baixeras, C., Barrio, J.A., Bartko, H., Bastieri, D., Becker, J.K., Bednarek, W., Berger, K., Bernardini, E., Biland, A., Bock, R.K., Bonnoli, G., Bordas, P., Borla Tridon, D., Bosch-Ramon, V., Bretz, T., Britvitch, I., Camara, M., Carmona, E., Chilingarian, A., Commichau, S., Contreras, J.L., Cortina, J., Costado, M.T., Covino, S., Curtef, V., Dazzi, F., De Angelis, A., De Cea del Pozo, E., de los Reyes, R., De Lotto, B., De Maria, M., De Sabata, F., Delgado Mendez, C., Dominguez, A., Dorner, D., Doro, M., Elsässer, D., Errando, M., Fagiolini, M., Ferenc, D., Fernández, E., Firpo, R., Fonseca, M.V., Font, L., Galante, N., García López, R.J., Garczarczyk, M., Gaug, M., Goebel, F., Hadasch, D., Hayashida, M., Herrero, A., Höhne, D., Hose, J., Hsu, C.C., Huber, S., Jogler, T., Kranich, D., La Barbera, A., Laille, A., Leonardo, E., Lindfors, E., Lombardi, S., Longo, F., López, M., Lorenz, E., Majumdar, P., Maneva, G., Mankuzhiyil, N., Mannheim, K., Maraschi, L., Mariotti, M., Martínez, M., Mazin, D., Meucci, M., Meyer, M., Miranda, J.M., Mirzoyan, R., Moles, M., Moralejo, A., Nieto, D., Nilsson, K., Ninkovic, J., Otte, N., Oya, I., Paoletti, R., Paredes, J.M., Pasanen, M., Pascoli, D., Pauss, F., Pegna, R.G., Perez-Torres, M.A., Persic, M., Peruzzo, L., Piccioli, A., Prada, F., Prandini, E., Puchades, N., Raymers, A., Rhode, W., Ribó, M., Rico, J., Rissi, M., Robert, A., Rügamer, S., Saggion, A., Saito, T.Y., Salvati, M., Sanchez-Conde, M., Sartori, P., Satalecka, K., Scalzotto, V., Scapin, V., Schweizer, T., Shayduk, M., Shinozaki, K., Shore, S.N., Sidro, N., Sierpowska-Bartosik, A., Sillanpää, A., Sitarek, J., Sobczynska, D., Spanier, F., Stamerra, A., Stark, L.S., Takalo, L., Tavecchio, F., Temnikov, P., Tescaro, D., Teshima, M., Tluczykont, M., Torres, D.F., Turini, N., Vankov, H., Venturini, A., Vitale, V., Wagner, R.M., Wittek, W., Zabalza, V., Zandanel, F., Zanin, R., and Zapatero, J.

Published
2009
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29. Subretinal Injection of Recombinant Tissue Plasminogen Activator and Gas Tamponade to Displace Acute Submacular Haemorrhages Secondary to Age-Related Macular Degeneration

Author

Iannetta D, De Maria M, Bolletta E, Mastrofilippo V, Moramarco A, and Fontana L

Subjects
macular degeneration, submacular haemorrhage, recombinant tissue plasminogen activator, pars plana vitrectomy, subretinal injection, Ophthalmology, RE1-994
Abstract

Danilo Iannetta,1 Michele De Maria,1 Elena Bolletta,2 Valentina Mastrofilippo,1 Antonio Moramarco,1 Luigi Fontana1 1Ophthalmology Unit, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy; 2Ocular Immunology Unit, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, ItalyCorrespondence: Danilo IannettaOphthalmology Unit, AUSL-IRCCS Reggio Emilia, Viale Risorgimento 80, Reggio Emilia, ItalyTel +39 0522296520Fax +39 0522295839Email iannettadanilo@gmail.comPurpose: To analyse the efficacy of subretinal injection of recombinant tissue plasminogen activator (rtPA) and gas tamponade for the displacement of submacular haemorrhage (SMH).Methods: This single-centre, retrospective, case series included 25 consecutive patients (25 eyes) who underwent pars plana vitrectomy (PPV) with subretinal rtPA injection and 20% sulphur hexafluoride (SF6) tamponade. The primary outcome was SMH displacement rate, defined as the absence of subretinal blood within (complete) or outside (partial) 1500 μm centred on the fovea one month after PPV. Secondary outcomes were final best-corrected visual acuity (BCVA), central macular thickness (CMT), recurrence probability, number of anti-vascular endothelial growth factor (VEGF) injections after PPV, and intra- and post-operative complications.Results: Successful displacement was obtained in all 25 eyes (100%), with complete and partial displacement obtained in 15 (60%) and 10 (40%), respectively. BCVA significantly improved from 1.81± 0.33 to 1.37± 0.52 LogMar at 12 months from surgery (p = 0.001). The bivariate correlation analysis revealed that earlier the surgery had better visual prognosis at the end of the follow-up (p = 0.007). CMT significantly decreased from 922 ± 273.69 μm at baseline to 403.53 ± 314.64 μm at 12 months follow-up (p < 0.001). SMH recurrence was observed in two (8%) patients with a mean survival time of 11.6 ± 0.339 months and a cumulative survival probability of 88% at the end of follow-up. After PPV, the mean number of anti-VEGF injections was 3.00 ± 0.957 with no correlation with final visual acuity (p = 0.365). No intraoperative complications were recorded. Only one patient developed open funnel retinal detachment 40 days after primary PPV.Conclusion: PPV with rtPA subretinal injection and SF6 tamponade is a safe and effective technique in displacing acute SMHs secondary to neovascular AMD. It is recommended to perform within 14 days from the onset of the symptoms to achieve BCVA improvement at 12 months and proper imaging to plan future anti-VEG treatment.Keywords: macular degeneration, submacular haemorrhage, recombinant tissue plasminogen activator, pars plana vitrectomy, subretinal injection

Published
2021

30. Measuring Anterior Chamber Inflammation After Cataract Surgery: A Review of the Literature Focusing on the Correlation with Cystoid Macular Edema

Author

De Maria M, Iannetta D, Cimino L, Coassin M, and Fontana L

Subjects
anterior chamber inflammation, cataract surgery, clinical grading, laser flare photometry, anterior segment optical coherence tomography, aqueous humour sample, cystoid macular edema, Ophthalmology, RE1-994
Abstract

Michele De Maria,1,2 Danilo Iannetta,1 Luca Cimino,3 Marco Coassin,4 Luigi Fontana1 1Ophthalmology Unit, AUSL-IRCCS of Reggio Emilia, Reggio Emilia, Italy; 2Clinical and Experimental Medicine Ph.D. Programme, University of Modena and Reggio Emilia, Modena, Italy; 3Ocular Immunology Unit, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy; 4Ophthalmology, University Campus Bio-Medico of Rome, Rome, ItalyCorrespondence: Luigi FontanaOphthalmology Unit, AUSL-IRCCS of Reggio Emilia, Viale Risorgimento 80, Reggio Emilia 42122, ItalyEmail luifonta@gmail.comAbstract: Cystoid macular edema (CME) is an infrequent, though potentially visually impairing, complication after uneventful cataract surgery. Rupture of the blood-aqueous barrier, with leakage of serum proteins into the aqueous humour, is the main pathogenic factor. However, only a few studies investigated the potential correlation between anterior chamber (AC) inflammation and the risk of cystoid macular changes occurring after surgery. This review aims to identify evidence of a correlation between AC inflammation and the risk of pseudophakic CME. One hundred eighty-seven prospective trials investigating AC inflammation after uncomplicated cataract surgery were identified. Methods of analysis of AC inflammation and the frequency of macular changes were recorded. In the majority (51%) of the studies, inflammation was assessed by clinical grading, followed by laser flare and cell photometry (LFCP) (42%) and aqueous humour sample (4%). Few studies (4%) adopted a combined LFCP and aqueous sample or clinical grading analysis. Sixteen (9%) studies investigated AC inflammation and macular changes by OCT (7%) or fluorescein angiography (2%). Correlation between the amount of postoperative AC inflammation and frequency of CME was documented in 7 studies, not confirmed in 2 studies, and not examined in the other 7. LFCP, more than the other methods of analysis, correlated with the frequency of CME postoperatively. Investigation of the relationship between AC inflammation and the risk of CME changes requires the adoption of quantitative methods of analysis of the inflammatory response after surgery. For this purpose, due to the low level of inflammation in the AC after uncomplicated cataract surgery, LFCP, more than subjective clinical grading, seems a more sensitive and reproducible method of measurement. Inflammation assessment after cataract surgery has a potential role in predicting the risk of CME development and may help to titrate the duration and intensity of treatment in relation to the surgical inflammatory response.Keywords: anterior chamber inflammation, cataract surgery, clinical grading, laser flare photometry, anterior segment optical coherence tomography, aqueous humour sample, cystoid macular edema

Published
2020

31. Probing quantum gravity using photons from a flare of the active galactic nucleus Markarian 501 observed by the MAGIC telescope

Author

Albert, J., Aliu, E., Anderhub, H., Antonelli, L.A., Antoranz, P., Backes, M., Baixeras, C., Barrio, J.A., Bartko, H., Bastieri, D., Becker, J.K., Bednarek, W., Berger, K., Bernardini, E., Bigongiari, C., Biland, A., Bock, R.K., Bonnoli, G., Bordas, P., Bosch-Ramon, V., Bretz, T., Britvitch, I., Camara, M., Carmona, E., Chilingarian, A., Commichau, S., Contreras, J.L., Cortina, J., Costado, M.T., Covino, S., Curtef, V., Dazzi, F., De Angelis, A., De Cea del Pozo, E., Delgado Mendez, C., de los Reyes, R., De Lotto, B., De Maria, M., De Sabata, F., Dominguez, A., Dorner, D., Doro, M., Errando, M., Fagiolini, M., Ferenc, D., Fernández, E., Firpo, R., Fonseca, M.V., Font, L., Galante, N., García López, R.J., Garczarczyk, M., Gaug, M., Goebel, F., Hayashida, M., Herrero, A., Höhne, D., Hose, J., Hsu, C.C., Huber, S., Jogler, T., Kranich, D., La Barbera, A., Laille, A., Leonardo, E., Lindfors, E., Lombardi, S., Longo, F., López, M., Lorenz, E., Majumdar, P., Maneva, G., Mankuzhiyil, N., Mannheim, K., Maraschi, L., Mariotti, M., Martínez, M., Mazin, D., Meucci, M., Meyer, M., Miranda, J.M., Mirzoyan, R., Moles, M., Moralejo, A., Nieto, D., Nilsson, K., Ninkovic, J., Otte, N., Oya, I., Panniello, M., Paoletti, R., Paredes, J.M., Pasanen, M., Pascoli, D., Pauss, F., Pegna, R.G., Perez-Torres, M.A., Persic, M., Peruzzo, L., Piccioli, A., Prada, F., Prandini, E., Puchades, N., Raymers, A., Rhode, W., Ribó, M., Rico, J., Rissi, M., Robert, A., Rügamer, S., Saggion, A., Saito, T.Y., Salvati, M., Sanchez-Conde, M., Sartori, P., Satalecka, K., Scalzotto, V., Scapin, V., Schmitt, R., Schweizer, T., Shayduk, M., Shinozaki, K., Sidro, N., Sierpowska-Bartosik, A., Sillanpää, A., Sobczynska, D., Spanier, F., Stamerra, A., Stark, L.S., Takalo, L., Tavecchio, F., Temnikov, P., Tescaro, D., Teshima, M., Tluczykont, M., Torres, D.F., Turini, N., Vankov, H., Venturini, A., Vitale, V., Wagner, R.M., Wittek, W., Zabalza, V., Zandanel, F., Zanin, R., Zapatero, J., Ellis, John, Mavromatos, N.E., Nanopoulos, D.V., Sakharov, A.S., and Sarkisyan, E.K.G.

Published
2008
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32. Evaluation of macular pigment optical density following femtosecond laser-assisted cataract surgery

Author

Verdina T, Date P, Benatti C, Lazzerini A, Fornasari E, De Maria M, Pellacani E, Forlini M, and Cavallini GM

Subjects
femtosecond laser, macular pigment, macular pigment optical density (MPOD), femtosecond laser-assisted cataract surgery (FLACS), bimanual microincision cataract surgery (B-MICS), flicker photometry, Ophthalmology, RE1-994
Abstract

Tommaso Verdina,1 Purva Date,2 Caterina Benatti,1 Andrea Lazzerini,1 Elisa Fornasari,1 Michele De Maria,3 Elena Pellacani,1 Matteo Forlini,4 Gian Maria Cavallini11Institute of Ophthalmology, University of Modena and Reggio Emilia, Modena, Italy; 2Aditya Jyot Eye Hospital, Mumbai, India; 3Clinical and Experimental Medicine PhD Program, University of Modena and Reggio Emilia, Modena, Italy; 4Domus Nova Hospital, Ravenna, ItalyBackground: To evaluate macular pigment optical density (MPOD) after bimanual femtosecond laser-assisted cataract surgery (FLACS) compared to standard bimanual phacoemulsification (B-MICS).Methods: A prospective, case matched, comparative cohort study conducted at the Institute of Ophthalmology, University of Modena and Reggio Emilia (Italy); 30 eyes underwent bimanual FLACS with low-energy Ziemer LDV Z8 (FLACS) and 30 underwent B-MICS standard technique (B-MICS). All interventions were conducted by the same expert surgeon. MPOD using the Macular Pigment Screener II (MPS II) was evaluated at baseline, 7 and 30 days after surgery. As secondary outcomes, we considered best corrected visual acuity (BCVA) and central macular thickness (CMT) obtained using optical coherence tomography.Results: In all cases, a BunnyLens AF IOL was safely implanted in the capsular bag through a 1.4 mm incision. We found a significant reduction in MPOD in both groups at 7 and 30 days; 0.16±0.14 and 0.10±0.12 (FLACS) and 0.18±0.13 and 0.15±0.14 (B-MICS), respectively (P

Published
2019

35. Vías de contaminación de la leche con esporas generadoras de gas butírico (clostridium) a partir del silaje consumido por las vacas lecheras.

Author

Nescier, I., Ramos, E., De María, M., Bonzi, E., Bonvin, C., and Thomas, J.

Abstract

Copyright of Revista FAVE is the property of Universidad Nacional del Litoral and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2015

38. Long-term follow-up for bimanual microincision cataract surgery: comparison of results obtained by surgeons in training and experienced surgeons

Author

Cavallini GM, Verdina T, Forlini M, Volante V, De Maria M, Torlai G, Benatti C, and Delvecchio G

Subjects
Bimanual microincision cataract surgery (B-MICS), clear corneal incisions, posterior capsule opacification, surgeons-in-training, Ophthalmology, RE1-994
Abstract

Gian Maria Cavallini, Tommaso Verdina, Matteo Forlini, Veronica Volante, Michele De Maria, Giulio Torlai, Caterina Benatti, Giancarlo Delvecchio Institute of Ophthalmology, University of Modena and Reggio Emilia, Modena, Italy Purpose: To determine the efficacy of bimanual microincision cataract surgery (B-MICS) performed by surgeons in training, evaluating clinical results, posterior capsule opacification (PCO) incidence, and clear corneal incision (CCI) architecture in a long-term follow-up and comparing results with those obtained by experienced surgeons. Patients and methods: Eighty eyes of 62 patients operated on by three surgeons in training who used B-MICS technique for the first time were included in the study (Group A). Eighty eyes of 59 patients who underwent B-MICS by three experienced surgeons were included as a control group (Group B). Best corrected visual acuity, astigmatism, corneal pachymetry, and endothelial cell count were evaluated before surgery and at 1 month and 18 months after surgery. Anterior segment optical coherence tomography images were obtained to study the morphology of CCIs. PCO incidence was evaluated using EPCO2000 software. Results: Out of 160 surgeries included in the study, mean best-corrected visual acuity improvement at 18 months was 0.343±0.246 logMAR for Group A, and 0.388±0.175 logMAR for Group B, respectively. We found no statistically significant induced astigmatism nor corneal pachymetry changes in either group, while we noticed a statistically significant endothelial cell loss postoperatively in both groups (P

Published
2016

39. Reversal of immune complex inhibition of antibody-dependent cell-mediated cytotoxicity by normal human serum.

Author

Isturiz, M. A., Fink, Susana B., De, María M., and de Bracco, E.

Subjects
BLOOD plasma, KILLER cells, IMMUNOGLOBULIN G, YEAST fungi, CELL receptors, SERUM
Abstract

The results of this study demonstrate that inhibition of antibody-dependent cell-mediated cytotoxicity (ADCC) of human peripheral blood mononuclear cells (PBMC) by ovalbumin (OA)-IgG anti-OA immune complexes (IC) can be reversed by normal human serum (NHS) or serum from a patient with congenital deficiency of the second component of complement (C2 def-HS) lacking activity of the classical complement (C) pathway. On the other hand, NHS that had been inactivated by heating at 56°C for 30 min (HI-NHS) or NHS depleted of the alternative C pathway activity by absorption with zymosan (Zy-NHS) did not restore the ADCC of IC-blocked PBMC. These results suggest that the alternative pathway of C plays a very important role in the re-establishment of ADCC of PBMC blocked with IC. The recovered activity was susceptible to a new inhibition when re-exposed to IC, demonstrating that the NHS effect depends on the recovery of the functional activity of the receptor for the Fc fragment of IgG on PBMC and not on the induction of non-specific cytotoxicity. The ability of NHS to restore the cytolytic potential of IC-inhibited PBMC was dependent on the time of exposure of PBMC to IC before the addition of the unblocking agent (NHS). After prolonged reaction of PBMC with IC, the blocked cells were unable to recover their ADCC activity by incubation with NHS. Unblocking of the Fc receptor of PBMC by C may be a physiological way to prevent permanent impairment of the immune mechanisms that depend on its function in the free state. [ABSTRACT FROM AUTHOR]

Published
1982

45. Chemical injury treated with autologous limbal epithelial stem cell transplantation and subconjunctival bevacizumab

Author

Cavallini GM, Pellegrini G, Volante V, Ducange P, De Maria M, Torlai G, Benatti C, and Forlini M

Subjects
Ophthalmology, RE1-994
Abstract

Gian Maria Cavallini,1 Graziella Pellegrini,2 Veronica Volante,1 Pietro Ducange,1 Michele De Maria,1 Giulio Torlai,1 Caterina Benatti,1 Matteo Forlini1 1Institute of Ophthalmology, 2Centre for Regenerative Medicine “Stefano Ferrari”, University of Modena e Reggio Emilia, Modena, Italy Background: Limbal stem cell (LSC) deficiency leads to corneal opacity due to a conjunctivalization of the corneal surface. LSC transplantation, which can be followed by corneal keratoplasty, is an effective procedure to restore corneal transparency; however, a common cause of failure of this procedure is neovascularization (NV).Methods: A 59-year-old man with a 21-year history of a corneal chemical burn caused by phosphoric acid in his left eye was examined. He presented with unilateral total LSC deficiency with severe conjunctivalization and a corrected distance visual acuity that was limited to hand motion.Results: We reported the short-term in vivo efficacy of subconjunctival bevacizumab for progressive corneal NV in a patient with LSC deficiency that underwent LSC transplantation. Four months after autologous LSC transplantation and 1 month after the second subconjunctival bevacizumab injection, the patient’s corrected distance visual acuity was 1/10.Conclusion: Subconjunctival injection of bevacizumab can reduce the corneal NV, reducing conjunctival inflammation and supporting restoration of a stable ocular surface that is able to counteract graft failure, with no toxicity for the transplanted LSC. Keywords: stem cells, bevacizumab, limbal stem cell deficiency, transplantation

Published
2014

46. Escorpionismo em Belo Horizonte, MG: um estudo retrospectivo

Author

Soares Marcely Regina Martins, Azevedo Cristiano Schetini de, and De Maria Mário

Subjects
Escorpionismo, Epidemiologia, Tityus serrulatus, Escorpião amarelo, Arctic medicine. Tropical medicine, RC955-962
Abstract

Os escorpiões (Arachnida, Scorpiones), especialmente na área urbana, devido à grande densidade demográfica e possibilidade de confronto, representam risco à saúde pública. A espécie Tityus serrulatus é a mais importante, do ponto de vista médico, causando o maior número de acidentes. Objetivou-se levantar dados epidemiológicos e a ocorrência de acidentes escorpiônicos em Belo Horizonte, entre 1990 e 1997. Os dados foram obtidos no Hospital de Pronto Socorro João XXIII. Ocorreram 3265 acidentes, sendo a maioria em 1996. Aconteceram 6 acidentes fatais. Com maior incidência nos meses de janeiro, o sexo masculino, os membros superiores e a faixa etária entre 25 e 65 anos, foram os mais atingidos. Os resultados constituem importante subsídio para o controle do escorpionismo, pois delimitam as áreas mais atingidas e o perfil dos acidentados, permitindo campanhas educativas e de prevenção mais eficientes.

Published
2002

48. Systematic assessment of long-read RNA-seq methods for transcript identification and quantification.

Author

Pardo-Palacios FJ, Wang D, Reese F, Diekhans M, Carbonell-Sala S, Williams B, Loveland JE, De María M, Adams MS, Balderrama-Gutierrez G, Behera AK, Gonzalez Martinez JM, Hunt T, Lagarde J, Liang CE, Li H, Meade MJ, Moraga Amador DA, Prjibelski AD, Birol I, Bostan H, Brooks AM, Çelik MH, Chen Y, Du MRM, Felton C, Göke J, Hafezqorani S, Herwig R, Kawaji H, Lee J, Li JL, Lienhard M, Mikheenko A, Mulligan D, Nip KM, Pertea M, Ritchie ME, Sim AD, Tang AD, Wan YK, Wang C, Wong BY, Yang C, Barnes I, Berry AE, Capella-Gutierrez S, Cousineau A, Dhillon N, Fernandez-Gonzalez JM, Ferrández-Peral L, Garcia-Reyero N, Götz S, Hernández-Ferrer C, Kondratova L, Liu T, Martinez-Martin A, Menor C, Mestre-Tomás J, Mudge JM, Panayotova NG, Paniagua A, Repchevsky D, Ren X, Rouchka E, Saint-John B, Sapena E, Sheynkman L, Smith ML, Suner MM, Takahashi H, Youngworth IA, Carninci P, Denslow ND, Guigó R, Hunter ME, Maehr R, Shen Y, Tilgner HU, Wold BJ, Vollmers C, Frankish A, Au KF, Sheynkman GM, Mortazavi A, Conesa A, and Brooks AN

Subjects
Humans, Animals, Mice, Transcriptome, Sequence Analysis, RNA methods, Molecular Sequence Annotation methods, RNA-Seq methods, Gene Expression Profiling methods
Abstract

The Long-read RNA-Seq Genome Annotation Assessment Project Consortium was formed to evaluate the effectiveness of long-read approaches for transcriptome analysis. Using different protocols and sequencing platforms, the consortium generated over 427 million long-read sequences from complementary DNA and direct RNA datasets, encompassing human, mouse and manatee species. Developers utilized these data to address challenges in transcript isoform detection, quantification and de novo transcript detection. The study revealed that libraries with longer, more accurate sequences produce more accurate transcripts than those with increased read depth, whereas greater read depth improved quantification accuracy. In well-annotated genomes, tools based on reference sequences demonstrated the best performance. Incorporating additional orthogonal data and replicate samples is advised when aiming to detect rare and novel transcripts or using reference-free approaches. This collaborative study offers a benchmark for current practices and provides direction for future method development in transcriptome analysis., (© 2024. The Author(s).)

Published
2024
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50. Systematic assessment of long-read RNA-seq methods for transcript identification and quantification.

Author

Pardo-Palacios FJ, Wang D, Reese F, Diekhans M, Carbonell-Sala S, Williams B, Loveland JE, De María M, Adams MS, Balderrama-Gutierrez G, Behera AK, Gonzalez JM, Hunt T, Lagarde J, Liang CE, Li H, Jerryd Meade M, Moraga Amador DA, Prjibelski AD, Birol I, Bostan H, Brooks AM, Hasan Çelik M, Chen Y, Du MRM, Felton C, Göke J, Hafezqorani S, Herwig R, Kawaji H, Lee J, Liang Li J, Lienhard M, Mikheenko A, Mulligan D, Ming Nip K, Pertea M, Ritchie ME, Sim AD, Tang AD, Kei Wan Y, Wang C, Wong BY, Yang C, Barnes I, Berry A, Capella S, Dhillon N, Fernandez-Gonzalez JM, Ferrández-Peral L, Garcia-Reyero N, Goetz S, Hernández-Ferrer C, Kondratova L, Liu T, Martinez-Martin A, Menor C, Mestre-Tomás J, Mudge JM, Panayotova NG, Paniagua A, Repchevsky D, Rouchka E, Saint-John B, Sapena E, Sheynkman L, Laird Smith M, Suner MM, Takahashi H, Youngworth IA, Carninci P, Denslow ND, Guigó R, Hunter ME, Tilgner HU, Wold BJ, Vollmers C, Frankish A, Fai Au K, Sheynkman GM, Mortazavi A, Conesa A, and Brooks AN

Abstract

The Long-read RNA-Seq Genome Annotation Assessment Project (LRGASP) Consortium was formed to evaluate the effectiveness of long-read approaches for transcriptome analysis. The consortium generated over 427 million long-read sequences from cDNA and direct RNA datasets, encompassing human, mouse, and manatee species, using different protocols and sequencing platforms. These data were utilized by developers to address challenges in transcript isoform detection and quantification, as well as de novo transcript isoform identification. The study revealed that libraries with longer, more accurate sequences produce more accurate transcripts than those with increased read depth, whereas greater read depth improved quantification accuracy. In well-annotated genomes, tools based on reference sequences demonstrated the best performance. When aiming to detect rare and novel transcripts or when using reference-free approaches, incorporating additional orthogonal data and replicate samples are advised. This collaborative study offers a benchmark for current practices and provides direction for future method development in transcriptome analysis., Competing Interests: Competing Interests Design of the project was discussed with Oxford Nanopore Technologies (ONT), Pacific Biosciences, and Lexogen. ONT provided partial support for flow cells and reagents. S.C-S and A.N.B. have received reimbursement for travel, accommodation, and conference fees to speak at events organized by ONT. A.N.B. is a consultant for Remix Therapeutics, Inc.

Published
2023
Full Text
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