411 results on '"De Brabander, Jef"'
Search Results
2. Anticancer benzoxaboroles block pre-mRNA processing by directly inhibiting CPSF3
3. Inducible mismatch repair streamlines forward genetic approaches to target identification of cytotoxic small molecules
4. Selective and brain-penetrant lanosterol synthase inhibitors target glioma stem-like cells by inducing 24(S),25-epoxycholesterol production
5. Molecular mechanism of the wake-promoting agent TAK-925
6. A convergent approach toward fidaxomicin: Syntheses of the fully glycosylated northern and southern fragments
7. Discovery and Optimization of N-Arylated Tetracyclic Dicarboximides That Target Primary Glioma Stem-like Cells
8. Novel orexin receptor agonists based on arene- or pyridine-fused 1,3-dihydro-2H-imidazole-2-imines
9. Thiophenyl Derivatives of Nicotinamide Are Metabolized by the NAD Salvage Pathway into Unnatural NAD Derivatives That Inhibit IMPDH and Are Toxic to Peripheral Nerve Cancers.
10. Total synthesis of sparstolonin B via a palladium-catalyzed aldehyde α-arylation
11. A biosynthetically inspired synthesis of (−)-berkelic acid and analogs
12. Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma
13. A Small Molecule Smac Mimic Potentiates TRAIL- and TNFα-Mediated Cell Death
14. An adipo-biliary-uridine axis that regulates energy homeostasis
15. Anticancer benzoxaboroles block pre-mRNA processing by directly inhibiting CPSF3
16. Synthesis and evaluation of analogs of 5′-(((Z)-4-amino-2-butenyl)methylamino)-5′-deoxyadenosine (MDL 73811, or AbeAdo) – An inhibitor of S-adenosylmethionine decarboxylase with antitrypanosomal activity
17. Obatoclax, saliphenylhalamide and gemcitabine inhibit Zika virus infection in vitro and differentially affect cellular signaling, transcription and metabolism
18. Triazoles inhibit cholesterol export from lysosomes by binding to NPC1
19. Metabolite Regulation of Nuclear Localization of Carbohydrate-response Element-binding Protein (ChREBP): ROLE OF AMP AS AN ALLOSTERIC INHIBITOR
20. Immuno-modulating properties of saliphenylhalamide, SNS-032, obatoclax, and gemcitabine
21. Structural basis for itraconazole-mediated NPC1 inhibition
22. Data from Biomarker Accessible and Chemically Addressable Mechanistic Subtypes of BRAF Melanoma
23. Supplementary Tables S1-S15 from Biomarker Accessible and Chemically Addressable Mechanistic Subtypes of BRAF Melanoma
24. Supplementary Text, Figure Legends, Figures S1-S12 from Biomarker Accessible and Chemically Addressable Mechanistic Subtypes of BRAF Melanoma
25. Supplementary Methods from Biomarker Accessible and Chemically Addressable Mechanistic Subtypes of BRAF Melanoma
26. Vacuolar ATPase in Phagosome-Lysosome Fusion
27. Inducible mismatch repair streamlines forward genetic approaches to target identification of cytotoxic small molecules
28. Inducible mismatch repair streamlines forward genetic approaches to target identification of cytotoxic small molecules
29. Evaluation of the efficacy of the hypocretin/orexin receptor agonists TAK ‐925 and ARN ‐776 in narcolepticorexin/tTA; TetO‐DTAmice
30. Evaluation of the Efficacy of the Hypocretin/orexin Receptor Agonists TAK-925 and ARN-776 in NarcolepticOrexin/tTA; TetO-DTAMice
31. Systematic Identification of Molecular Subtype-Selective Vulnerabilities in Non-Small-Cell Lung Cancer
32. A room temperature copper catalyzed N-selective arylation of β-amino alcohols with iodoanilines and aryl iodides
33. Evaluation of the efficacy of the hypocretin/orexin receptor agonists TAK‐925 and ARN‐776 in narcoleptic orexin/tTA; TetO‐DTA mice.
34. TK216 targets microtubules in Ewing sarcoma cells
35. Obatoclax, Saliphenylhalamide, and Gemcitabine Inhibit Influenza A Virus Infection
36. Novel Bcl-2 Inhibitors Selectively Disrupt the Autophagy-Specific Bcl-2–Beclin 1 Protein–Protein Interaction
37. Heterocycles via intramolecular platinum-catalyzed propargylic substitution
38. Regulation of kynurenine biosynthesis during influenza virus infection
39. Discovery of a Proneurogenic, Neuroprotective Chemical
40. TK216 targets microtubules in Ewing sarcoma cells
41. The proton translocation domain of cellular vacuolar ATPase provides a target for the treatment of influenza A virus infections
42. A Multipronged Approach Establishes Covalent Modification of β-Tubulin as the Mode of Action of Benzamide Anti-cancer Toxins
43. The structure of importin α and the nuclear localization peptide of ChREBP, and small compound inhibitors of ChREBP–importin α interactions
44. A Medicinal Chemistry-Driven Approach Identified the Sterol Isomerase EBP as the Molecular Target of TASIN Colorectal Cancer Toxins
45. Cholesterol and 25-Hydroxycholesterol Inhibit Activation of SREBPs by Different Mechanisms, Both Involving SCAP and Insigs
46. Salicylihalamide A Inhibits the V0 Sector of the V-ATPase through a Mechanism Distinct from Bafilomycin A1
47. Ring-closing metathesis: a powerful tool for the synthesis of simplified salicylihalamide-based V-ATPase inhibitors
48. Design and Synthesis of TASIN Analogues Specifically Targeting Colorectal Cancer Cell Lines with Mutant Adenomatous Polyposis Coli (APC)
49. Isolation, Structure, and Total Synthesis of the Marine Macrolide Mangrolide D
50. The structure of importin α and the nuclear localization peptide of ChREBP, and small compound inhibitors of ChREBP-importin α interactions.
Catalog
Books, media, physical & digital resources
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.