202 results on '"Dawson, John C."'
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2. Discovery of senolytics using machine learning
3. Chemogenomic library design strategies for precision oncology, applied to phenotypic profiling of glioblastoma patient cells
4. Characterisation of a nucleo-adhesome
5. Application of a High-Content Screening Assay Utilizing Primary Human Lung Fibroblasts to Identify Antifibrotic Drugs for Rapid Repurposing in COVID-19 Patients
6. High-content phenotypic and pathway profiling to advance drug discovery in diseases of unmet need
7. Targeting FAK in anticancer combination therapies
8. Drug Screening Platforms and RPPA
9. High content phenotypic screening identifies serotonin receptor modulators with selective activity upon breast cancer cell cycle and cytokine signaling pathways
10. Morphological profiling in human neural progenitor cells classifies hits in a pilot drug screen for Alzheimer’s disease
11. A targetable PREX2/RAC1/PI3Kβ signalling axis confers resistance to clinically relevant therapeutic approaches in melanoma
12. Evaluation of Machine Learning Classifiers to Predict Compound Mechanism of Action When Transferred across Distinct Cell Lines
13. A novel ILK/STAT3 pathway controls plasticity in a neural stem cell model of glioblastoma.
14. Trichoplein binds PCM1 and controls endothelial cell function by regulating autophagy
15. Abstract 4031: In vivo studies demonstrate differences in target inhibition and anticancer efficacy between NXP900 and dasatinib in ovarian clear cell carcinoma model
16. Supplementary Table S1 from A Synergistic Anticancer FAK and HDAC Inhibitor Combination Discovered by a Novel Chemical–Genetic High-Content Phenotypic Screen
17. Supplementary Fig. S1 from A Synergistic Anticancer FAK and HDAC Inhibitor Combination Discovered by a Novel Chemical–Genetic High-Content Phenotypic Screen
18. Supplementary Text from A Synergistic Anticancer FAK and HDAC Inhibitor Combination Discovered by a Novel Chemical–Genetic High-Content Phenotypic Screen
19. Discovery of senolytics using machine learning
20. Code and data for 'Discovery of senolytics using machine learning' [Dataset]
21. A novel ILK/STAT3 pathway controls plasticity in a neural stem cell model of glioblastoma
22. Bistability in the Rac1, PAK, and RhoA Signaling Network Drives Actin Cytoskeleton Dynamics and Cell Motility Switches
23. High-Dimensional Profiling: The Theta Comparative Cell Scoring Method
24. Ovarian cancer cell lines derived from non-serous carcinomas migrate and invade more aggressively than those derived from high-grade serous carcinomas
25. Data from Kindlin-1 Promotes Pulmonary Breast Cancer Metastasis
26. Figure S1 from Kindlin-1 Promotes Pulmonary Breast Cancer Metastasis
27. Supplementary Data from A Conformation Selective Mode of Inhibiting SRC Improves Drug Efficacy and Tolerability
28. Supplementary Methods from Kindlin-1 Promotes Pulmonary Breast Cancer Metastasis
29. Table S1 from Kindlin-1 Promotes Pulmonary Breast Cancer Metastasis
30. Data from A Conformation Selective Mode of Inhibiting SRC Improves Drug Efficacy and Tolerability
31. Phenonaut: multiomics data integration for phenotypic space exploration
32. 11β-HSD1 inhibition does not affect murine tumour angiogenesis but may exert a selective effect on tumour growth by modulating inflammation and fibrosis
33. Patient derived glioma stem cell spheroid reporter assays for live cell high content analysis
34. Morphological profiling by Cell Painting in human neural progenitor cells classifies hit compounds in a pilot drug screen for Alzheimer’s disease
35. Discovery of new senolytics using machine learning
36. Characterisation of a nucleo-adhesome
37. Discovery of new senolytics using machine learning
38. Financial Intermediation and Financial Accounts
39. A Novel High-Content Phenotypic Screen To Identify Inhibitors of Mitochondrial DNA Maintenance in Trypanosomes
40. A novel mode of inhibiting SRC improves drug efficacy and tolerability
41. Pathway profiling of a novel SRC inhibitor, AZD0424, in combination with MEK inhibitors for cancer treatment
42. A Cyclical Model for Postwar U.S. Financial Markets
43. A Suggestion as to the Source of Montaigne's Title: "Essais"
44. Characterisation of a nucleo-adhesome
45. Pathway profiling of a novel SRC inhibitor, AZD0424, in combination with MEK inhibitors
46. A Conformation Selective Mode of Inhibiting SRC Improves Drug Efficacy and Tolerability
47. 11β-HSD1 inhibition does not affect murine tumour angiogenesis but may exert a selective effect on tumour growth by modulating inflammation and fibrosis
48. sj-pdf-1-jbx-10.1177_24725552211019405 – Supplemental material for Application of a High-Content Screening Assay Utilizing Primary Human Lung Fibroblasts to Identify Antifibrotic Drugs for Rapid Repurposing in COVID-19 Patients
49. A conformation selective mode of inhibiting SRC improves drug efficacy and tolerability
50. Bar domain proteins: a role in tubulation, scission and actin assembly in clathrin-mediated endocytosis
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