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In the Tropical Andes, a wide range of topographic and climatic settings results in a large diversity of glaciers distributed over mountain ranges and volcanoes. Previous studies, based on geodetic estimations, show that glaciers in this region have lost mass at a rate of -0.50 m w.e. yr-1 during the last two decades. At the interannual time step, efforts to understand the mass balance variability as a direct response to the Andean climate, have been constrained by the number of available observations and a variety of interpolation approaches used to compute the glaciological mass balances. Thanks to the availability of point mass balance on seven tropical glaciers, we assess the annual signal of the surface mass balances during the 1990-2020 period. Thus, glaciers in the inner tropics are subjected to a less pronounced mass loss of -0.35 m w.e. yr-1, while glaciers in the outer tropics exhibit a mass balance of -0.55 m w.e. yr-1. Our results suggest that this contrasting behavior may be related to the latitudinal location and elevation of glaciers. The interannual cycles captured by the point mass balance correlate with climate variability and periodical patterns as El Niño Southern Oscillation. Although its behavior depends on the climatic conditions at the regional scale and the local topography, on the whole, glaciers are shrinking throughout the region with negative consequences in terms of water availability for Andean countries., The 28th IUGG General Assembly (IUGG2023) (Berlin 2023)

O artigo traz a evolução e a contribuição da produção científica relacionada ao conceito de vulnerabilidade e sua potencialidade em estudos das doenças transmissíveis. Apresenta-se o conceito de Vulnerabilidade e a produção do conhecimento em Enfermagem, particularmente desenvolvida no Grupo Pesquisa Vulnerabilidade, Adesão e Necessidades em Saúde, do CNPq. Tem como finalidade ampliar a compreensão de agravos de saúde, com base neste conceito, além de possibilitar a proposição de intervenções para o seu enfrentamento, que extrapolem o âmbito do indivíduo, mas contemple a organização do trabalho nos serviços de saúde e a determinação social do processo saúde-doença. This article presents the evolution and the contribution of the scientific production related to the concept of vulnerability and its potential to help studying transmissible diseases. It presents the concept of vulnerability and the production of knowledge in nursing, developed particularly by the CNPq Research Group Vulnerability, Adherence, and Health Needs. The purpose is to improve the understanding of health issues, based on this concept, and permit the proposition of coping interventions that surpass the individual domain, thus contemplating the organization of health care work and the social determination of the health-disease process. El artículo se refiere a la evolución y a la contribución de la producción científica relacionada al concepto de vulnerabilidad y su potencialidad en estudios de las enfermedades contagiosas. Se presenta el concepto de Vulnerabilidad y la producción de conocimiento en Enfermería, particularmente, desarrollada en el Grupo de Investigación Vulnerabilidad, Adhesión y Necesidades en Salud, del CNPq. Tiene como finalidad ampliar la comprensión de perjuicios de salud con base en este concepto, además de posibilitar la propuesta de intervenciones para su enfrentamiento que extrapolen el ámbito del individuo, pero que contemple la organización del trabajo en los servicios de salud y la determinación social del proceso salud-enfermedad.

The evolution of treatment of chronic hepatitis C virus infection has led to improved therapeutic efficacy. However, a major problem is the presence of side effects that require modification or withdrawal of drug therapy in 15-20% of cases. This could potentially influence the lack of sustained viral response in 50% of the cases. Side effects are common, even with pegylated interferon. This study aimed to assess the incidence and severity of infections based on the development of neutropenia associated with combined therapy with pegylated interferon-alpha2a plus ribavirin in 209 patients with chronic hepatitis C infection. All patients were administered pegylated interferon-alpha2a (180 microg/week) plus ribavirin (800 mg/day for 24 weeks in cases of nongenotype 1, or 1000-1200 mg/day for 48 weeks for genotype 1, according to whether patients weighed more or less than 75 kg). Patients with preexisting neutropenia of any cause or cirrhosis were excluded. Neutropenia was defined as a neutrophil count (NC) of