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5. A Pilot Study of Reproductive Health and Anti-Müllerian Hormone Levels Among Female Firefighters

Author

Davidson, Samantha Nicole and Davidson, Samantha Nicole

Abstract

Background: Female firefighters may be highly exposed to chemicals through their job, which may negatively impact their reproductive health. Anti-müllerian hormone (AMH) is a clinical marker of ovarian reserve and may be influenced by environmental and occupational exposures but few studies have measured AMH on a population-level. Therefore, the objective of this study was to investigate whether AMH levels differed in female firefighters compared to comparison women and to investigate whether there is a dose-dependent relationship between years of firefighting and AMH levels among female firefighters. Methods: Firefighters, recruited from a pre-existing female firefighter cohort, completed a cross-sectional survey regarding their occupational history and were asked to recruit a non-firefighter friend or relative. All participants completed a questionnaire and provided a dried blood spot (DBS) sample where we measured their AMH level. For the analysis, AMH was log-transformed. Linear regression was used to assess the relationship between firefighting status and log transformed AMH levels. Models were adjusted for age, age2, and current hormonal contraceptive use. Percent differences and 95% confidence intervals (CIs) in AMH between exposure groups were calculated from the βs using ([exp(β) −1] *100) and presented with corresponding 95% CIs. Models were stratified by body mass index (BMI) to investigate possible effect modification. Among firefighters, we also investigated the influence of firefighting-related exposures. Sensitivity analyses excluded women with confirmed or suspected Polycystic ovarian syndrome (PCOS) (AMH 10ng/ml). Results: In our sample, firefighters (n=86) and non-firefighters (n=54) had similar mean age and BMI. Firefighters were more likely to report a history of infertility (18.6%) compared to non-firefighters (5.6%). Firefighters worked mainly as firefighters, drivers, or operators (41.9%). Over half of firefighters reported poor fit of at lea

Published
2021

10. S100‐negative indeterminate cell histiocytosis: in an eight‐month‐old boy.

Author

Kong, Fleur W., Read, Jazlyn, Pitney, Lucy, Tang, Fiona, Davidson, Samantha, and Wheller, Laura

Subjects
ERDHEIM-Chester disease, AFRICAN American children, INTERSTITIAL cells
Abstract

The two main groups of this disease process are Langerhans and non-Langerhans cell histiocytosis, with indeterminate cell histiocytosis showing immunophenotypic features of both.1 Indeterminate cell histiocytosis was first reported by Wood et al. in 1985 as a rare disorder characterised by a proliferation of dendritic cells.2 Immunophenotypic expression is characterised by positive CD1a, positive CD68, and faint or focal S-100. S100-negative, CD1a-positive cutaneous histiocytosis in a patient with S100-positive, CD1a-positive pulmonary histiocytosis. Cutaneous S100-negative, CD1a-positive histiocytosis successfully treated with combination therapy of oral methotrexate and corticosteroid. [Extracted from the article]

Published
2021
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11. Consensus statement for the treatment of infantile haemangiomas with propranolol

Author

Smithson, Sarah L, primary, Rademaker, Marius, additional, Adams, Susan, additional, Bade, Stuart, additional, Bekhor, Philip, additional, Davidson, Samantha, additional, Dore, Amanda, additional, Drummond, Catherine, additional, Fischer, Gayle, additional, Gin, Alexander, additional, Grills, Claire, additional, Halbert, Anne, additional, Lokmic, Zerina, additional, McCahon, Emma, additional, Morgan, Vanessa A, additional, Murrell, Dedee F, additional, Orchard, David, additional, Penington, Anthony, additional, Purvis, Diana, additional, Relic, John, additional, Robertson, Susan, additional, Robinson, Aaron J, additional, Scardamaglia, Laura, additional, Su, John, additional, Tan, Swee, additional, Wargon, Orli, additional, Warren, Lachlan, additional, Wong, Li‐chuen, additional, Zappala, Tania, additional, and Phillips, Roderic, additional

Published
2017
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14. Insights Derived from the Structure of Human Adenovirus

Author

Davidson, Samantha, primary, Debenham, William, additional, Wilson, Kristy, additional, McCraine, Kyrsten, additional, McCarthy, Jared, additional, McCarthy, Aaron, additional, Lee, Libby, additional, Davidson, Katie, additional, Galea‐Martinez, Sandra A., additional, and Reddy, Vijay, additional

Published
2011
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