16 results on '"David P. Mullin"'
Search Results
2. Bipedicled submental musculofascial 'hammock' flap for salvage laryngectomy closure reinforcement
- Author
-
Brent A. Chang, David G. Lott, Brittany E. Howard, Thomas H. Nagel, Richard E. Hayden, Michael L. Hinni, Carrlene B. Donald, David P. Mullin, and Andrew K. Patel
- Subjects
Novel technique ,Salvage Therapy ,medicine.medical_specialty ,Salvage laryngectomy ,business.industry ,Cutaneous Fistula ,Retrospective cohort study ,Laryngectomy ,Pharyngocutaneous Fistula ,Pharyngeal Diseases ,Surgical Flaps ,Surgery ,Postoperative Complications ,Otorhinolaryngology ,Submental flap ,medicine ,Humans ,business ,Laryngeal Neoplasms ,Retrospective Studies - Abstract
BACKGROUND The aim of the study was to describe a novel technique for reinforcement of salvage laryngectomy closure using a bipedicled musculofascial submental flap. METHODS A retrospective cohort study design identified patients who underwent salvage laryngectomy reinforcement with a bipedicled submental hammock flap between January 2008 and December 2016 were compared to salvage laryngectomy patients treated with primary closure of the neopharynx during the same time period. Pharyngocutaneous fistula rates were compared between groups. RESULTS Pharyngocutaneous fistula rate in the submental hammock group (2/31, 6.5%) was significantly lower compared to the primary closure group (14/45, 31%, P
- Published
- 2020
3. Parathyroid Computed Tomography Angiography: Early Experience with a Novel Imaging Technique in Primary Hyperparathyroidism
- Author
-
Terence E. Johnson, Gregory G. Capra, Isaac E Schwartz, Gilbert Boswell, and David P. Mullin
- Subjects
Adult ,Male ,medicine.medical_specialty ,Computed Tomography Angiography ,Computed tomography ,Parathyroid Glands ,03 medical and health sciences ,0302 clinical medicine ,Medicine ,Humans ,030223 otorhinolaryngology ,Radiometry ,Computed tomography angiography ,Aged ,Retrospective Studies ,medicine.diagnostic_test ,business.industry ,Reproducibility of Results ,Middle Aged ,medicine.disease ,Hyperparathyroidism, Primary ,Otorhinolaryngology ,030220 oncology & carcinogenesis ,Surgery ,Female ,Imaging technique ,Radiology ,Parathyroid surgery ,business ,Primary hyperparathyroidism ,Preoperative imaging - Abstract
To describe parathyroid computed tomography angiography (PCTA), determine its accuracy, and, as a secondary objective, calculate its mean radiation dosimetry.Retrospective chart review of patients who underwent parathyroidectomy for primary hyperparathyroidism from 2007 to 2015.Single-center tertiary care academic military hospital.PCTA is a 2-phase computed tomography imaging technique that uses individualized timing of contrast infusion and novel patient positioning to accurately identify parathyroid adenomas. Consecutive patients who underwent parathyroidectomy for primary hyperparathyroidism from 2007 to 2015 were reviewed; 55% of patients were women. The mean age was 50.9 years (range, 26-68 years). Sensitivity and specificity were calculated as well as mean radiation dosimetry and timing of contrast.A total of 108 procedures were performed during the study period. Twenty-one patients undergoing 22 PCTAs after prior sestamibi scans were nonlocalizing or equivocal. In this group, there were 15 true-positive, 3 false-positive, 4 true-negative, and 0 false-negative PCTAs. This represents a sensitivity of 100% (95% CI, 74.7%-100%) and a specificity of 57% (95% CI, 20%-88%). The mean calculated radiation dose was 5.15 mSv. In the most recent studies, a mean dose of 4.1 mSv was calculated. The ideal time of image acquisition contrast administration varied from 20 to 30 seconds after contrast infusion.PCTA is a new technique in anatomic imaging for hyperparathyroidism. In a single-center, single-radiologist retrospective study, it demonstrates excellent accuracy for patients with parathyroid adenomas that are otherwise difficult to localize preoperatively. Preliminary experience suggests that its use may be indicated as a primary imaging modality in the future.
- Published
- 2019
4. Pleomorphic rhabdomyosarcoma presenting as a hypopharyngeal mass
- Author
-
Christopher M. Johnson, David P. Mullin, Guerard P. Grice, Ryan A. Crane, and Kevin K. Bach
- Subjects
medicine.medical_specialty ,medicine.diagnostic_test ,business.industry ,Pharynx ,Head and neck cancer ,medicine.disease ,Malignancy ,Surgery ,Endoscopy ,medicine.anatomical_structure ,Otorhinolaryngology ,Biopsy ,medicine ,Medical history ,Differential diagnosis ,Rhabdomyosarcoma ,business - Abstract
Background Rhabdomyosarcoma (RMS) is a rare malignancy derived from skeletal muscle with approximately 40% of cases involving the head and neck. The pleomorphic variant, however, most commonly occurs in the extremities and has never, to our knowledge, been described in the pharynx. Methods A 46-year-old man with no significant medical history presented to the emergency department complaining of hemoptysis. A CT scan of the head and neck revealed a hypopharyngeal mass originally favored to be a benign process. Results Operative endoscopy revealed a previously unseen mucosal ulceration, and subsequent biopsy resulted in the final diagnosis of pleomorphic RMS. Conclusion Although quite rare, RMS should be considered in the differential diagnosis of a hypopharyngeal mass. This articleis a U.S. Government work and is in the public domain in the USA. Head Neck 37: E85–E87, 2015
- Published
- 2015
- Full Text
- View/download PDF
5. Reconstruction of the segmental mandibular defect
- Author
-
David P. Mullin, Richard E. Hayden, and Andrew K. Patel
- Subjects
Microsurgery ,Bone Transplantation ,Standard of care ,business.industry ,Mandibular Osteotomy ,Dentistry ,Context (language use) ,Mandible ,Free Tissue Flaps ,Mandibular osteotomy ,Mandibular Neoplasms ,stomatognathic diseases ,Osteoradionecrosis ,Surgery, Computer-Assisted ,Otorhinolaryngology ,Medicine ,Mandibular Diseases ,Surgery ,Mandibular Reconstruction ,Mouth Rehabilitation ,business - Abstract
This article reviews literature pertaining to advances in the reconstruction of segmental mandibular defects in the context of an established standard of care, microvascular transfer of free osteocutaneous flaps.Most literature reiterates established reconstructive techniques. Exceptions include the use of computer-assisted modeling to preoperatively design the excision of both the mandible and fibula segments and to produce a template for contouring the neomandible, the design of new flaps, distraction osteogenesis and techniques for dealing with osteonecrosis.The microvascular transfer of free osteocutaneous flaps remains the standard of care, with the fibula flap the clear favorite. Review of the evolution of this flap for segmental mandibular reconstruction provides the bulk of the literature. Improvement on this standard of practice continues to be elusive, in large part because of the effects of associated radiation. Tissue engineering holds promise but no current practical application is available.
- Published
- 2012
- Full Text
- View/download PDF
6. Paranasal Sinus Mucocele
- Author
-
David P. Mullin, Gregory G. Capra, and Peter N. Carbone
- Subjects
Sine qua non Radiology-Pathology ,Pathology ,medicine.medical_specialty ,Mucocele ,Pathology and Forensic Medicine ,Paranasal Sinus Diseases ,otorhinolaryngologic diseases ,Humans ,Medicine ,Sinus (anatomy) ,medicine.diagnostic_test ,business.industry ,Granulation tissue ,Magnetic resonance imaging ,Middle Aged ,medicine.disease ,Paranasal Sinus Mucocele ,Skull ,medicine.anatomical_structure ,Oncology ,Otorhinolaryngology ,Female ,business ,Orbit (anatomy) - Abstract
Paranasal sinus mucoceles are epithelium-lined cystic masses usually resulting from obstruction of sinus ostia. They most frequently occur in the frontal and ethmoid sinuses. While ophthalmologic symptoms are most common, patients also report rhinological or neurological complaints. The close proximity of paranasal sinus mucoceles to the orbit and skull base predisposes the patient to significant morbidity. Computed tomography displays a non-enhancing homogenous mass with expansion of bony walls. Magnetic resonance imaging reveals variable intensity of T1-weighted images and a hyperintense mass on T2-weighted images. Histopathologically mucoceles have features of respiratory mucosa with areas of reactive bone formation, hemorrhage, fibrosis, and granulation tissue. Surgical excision is the standard treatment with trends towards endoscopic techniques.
- Published
- 2012
- Full Text
- View/download PDF
7. Effects of Tympanomeatal Blunting on Sound Transfer Function
- Author
-
Jianzhong Liu, Ben J. Balough, Travis J. Pfannenstiel, Xianxi Ge, Ronald L. Jackson, and David P. Mullin
- Subjects
medicine.medical_specialty ,Tympanic Membrane ,Round window ,business.industry ,Temporal Bone ,Laser Doppler velocimetry ,Surgery ,Sound ,Tympanoplasty ,medicine.anatomical_structure ,Acoustic Stimulation ,Round Window, Ear ,Otorhinolaryngology ,Cadaver ,Temporal bone ,Middle ear ,medicine ,Humans ,Sound pressure ,Cadaveric spasm ,business ,Laser Doppler vibrometer ,Biomedical engineering - Abstract
(1) To measure the peak-to-peak displacement of the round window membrane (RWM) prior to blunting procedure. (2) To evaluate the impact of blunting the anterior tympanomeatal angle (ATA) on middle ear sound transfer function.Basic science study. Setting. Cadaveric temporal bone research laboratory.Six fresh human temporal bones were prepared using a mastoidectomy and facial recess approach. Baseline RWM peak-to-peak displacements were obtained by single-point laser Doppler vibrometry (LDV) at 90-dB sound pressure level over a spectrum of 250 to 8000 Hz. Temporalis muscle was harvested and then fashioned into a graft for each temporal bone, mimicking ATA blunting. RWM displacement responses with the blunted ATA were measured using the LDV to judge the impact on middle ear transfer function.For each of the 6 temporal bones, the average displacement decreased across all sound frequencies with the ATA blunting when compared with baseline (no blunting). Baseline velocity measurements for all sound signals averaged 4.5 × 10(-3) ± 1.892 × 10(-3) (mean ± SEM) mm/s, while measurements averaged 2.2 ± 6.62 × 10(-4) mm/s with blunting of the ATA (P.001). This amounted to a 52% decrease in velocity of the RWM following blunting of the ATA.Blunting of the ATA decreases the sound transfer function of the tympanic membrane and middle ear. Prevention of blunting at the ATA during tympanoplasty should be emphasized.
- Published
- 2011
- Full Text
- View/download PDF
8. Nodular Fasciitis of the Nasal Cavity: A Case Report
- Author
-
Fred Lindsay, Michael A. Keefe, and David P. Mullin
- Subjects
Nasal cavity ,medicine.medical_specialty ,business.industry ,Radiography ,Nodular fasciitis ,medicine.disease ,Surgery ,Resection ,medicine.anatomical_structure ,Otorhinolaryngology ,Medicine ,Primary treatment ,Presentation (obstetrics) ,business ,Head and neck - Abstract
Nodular fasciitis is an uncommon tumor-like fibroblastic proliferation of the head and neck that is difficult to differentiate from its more malignant counterparts. Despite modern advances, making this distinction is challenging because the clinical presentation is nonspecific and the histologic and radiologic features are variable. Once nodular fasciitis is diagnosed, the primary treatment is conservative resection and observation. We describe a case of nodular fasciitis of the nasal cavity in a 43-year-old woman. To the best of our knowledge, this is only the second reported case of nodular fasciitis arising in the nasal cavity, and the first such case in an adult.
- Published
- 2007
- Full Text
- View/download PDF
9. Radiofrequency Coblation Versus Intramural Bipolar Cautery for the Treatment of Inferior Turbinate Hypertrophy
- Author
-
Anil N. Shah, David P. Mullin, Kelly Mitzen, and Douglas Brewster
- Subjects
Adult ,Male ,Rhinometry, Acoustic ,medicine.medical_specialty ,Comparative Effectiveness Research ,Visual analogue scale ,Nostril ,Objective data ,Turbinates ,Muscle hypertrophy ,Subjective improvement ,Acoustic rhinometry ,Electrocoagulation ,Medicine ,Humans ,Postoperative Period ,Prospective Studies ,Prospective cohort study ,Pain Measurement ,Nasal endoscopy ,Pain, Postoperative ,Adult patients ,business.industry ,General Medicine ,Hypertrophy ,Rhinomanometry ,Surgery ,medicine.anatomical_structure ,Treatment Outcome ,Otorhinolaryngology ,Catheter Ablation ,Female ,Nasal Obstruction ,business ,Blinded study - Abstract
Objective: Compare intramural bipolar electrocautery and radiofrequency coblation in the treatment of inferior turbinate hypertrophy with regards to objective and subjective improvement in nasal obstruction, rate and type of complications, experience during the procedure, and rate of recovery. Study Design: Prospective, single-blinded study. Setting: Single tertiary medical center from 2008 to 2010. Subjects and Methods: Forty-one adult patients with inferior turbinate hypertrophy refractory to medical management were treated with radiofrequency coblation in one nostril and intramural bipolar cautery in the other. Subjective and objective data, including use of a Visual Analog Scale (VAS) for subjective outcomes, acoustic rhinometry, and nasal endoscopy, were then obtained from each patient comparing the 2 techniques. Results: Radiofrequency coblation was significantly less painful than intramural bipolar cautery during the procedure ( P = .03) and during the early postoperative period ( P < .02) and produced less crusting at 3 weeks ( P = .009). Both interventions were similar in subjective and objective improvements in nasal obstruction as measured by acoustic rhinometry and subjective VAS outcomes. Conclusion: Radiofrequency coblation seems to offer an equivalent alternative to bipolar electrocautery for the treatment of inferior turbinate hypertrophy with less discomfort during the procedure and early post-operative period.
- Published
- 2015
10. Subacute Hypoglossal Nerve Paresis with Internal Carotid Artery Dissection
- Author
-
David P. Mullin, Fred Lindsay, and Michael A. Keefe
- Subjects
Adult ,Male ,medicine.medical_specialty ,Administration, Oral ,Horner syndrome ,Carotid Artery, Internal, Dissection ,Hypoglossal Nerve Diseases ,Magnetic resonance angiography ,Diagnosis, Differential ,Dysarthria ,medicine ,Humans ,Cranial nerve disease ,Infusions, Intravenous ,Paresis ,Patient Care Team ,Internal carotid artery dissection ,medicine.diagnostic_test ,Heparin ,business.industry ,Anticoagulants ,medicine.disease ,Magnetic Resonance Imaging ,Surgery ,Hemiparesis ,Otorhinolaryngology ,Warfarin ,medicine.symptom ,business ,Hypoglossal nerve ,Magnetic Resonance Angiography - Abstract
Objectives To describe a case of an isolated hypoglossal nerve palsy in a patient with a spontaneous internal carotid artery dissection (ICAD). This condition is a well-recognized cause of cerebral ischemic stroke in patients younger than 45 years of age. Isolated cranial nerve neuropathy is a rare presentation. More common manifestations include incomplete hemiparesis, hemicrania, Horner syndrome, cervical bruit, pulsatile tinnitus, and multiple cranial nerve palsies. Methods A comprehensive literature search (Ovid, MEDLINE) for the presentation, diagnostic evaluation, treatment, and outcome of patients with internal carotid artery dissection was performed. Results A 43-year-old man presented with a 3-week history of mild dysarthria. There was no history of craniocervical trauma. The physical examination revealed an isolated left hypoglossal nerve paresis. Magnetic resonance imaging and angiography findings were consistent with a left skull base ICAD. The patient was successfully treated with anticoagulation therapy. The current rate of cranial nerve involvement is estimated at 10% of all ICADs. This is the second report of isolated hypoglossal nerve palsy without hemicrania in a case of atraumatic ICAD. Conclusions Patients with an ICAD infrequently present to the otolaryngologist because of its head and neck manifestations. It is crucial to recognize atypical findings and to perform an accurate and prompt diagnostic evaluation. The foundation of treatment is aggressive anticoagulation, with surgical or radiologic intervention reserved for cases demonstrating life-threatening progression.
- Published
- 2003
- Full Text
- View/download PDF
11. Pleomorphic rhabdomyosarcoma presenting as a hypopharyngeal mass
- Author
-
Ryan A, Crane, Christopher M, Johnson, Guerard P, Grice, David P, Mullin, and Kevin K, Bach
- Subjects
Diagnosis, Differential ,Male ,Hemoptysis ,Hypopharynx ,Hypopharyngeal Neoplasms ,Rhabdomyosarcoma ,Humans ,Laryngoscopes ,Middle Aged ,Tomography, X-Ray Computed - Abstract
Rhabdomyosarcoma (RMS) is a rare malignancy derived from skeletal muscle with approximately 40% of cases involving the head and neck. The pleomorphic variant, however, most commonly occurs in the extremities and has never, to our knowledge, been described in the pharynx.A 46-year-old man with no significant medical history presented to the emergency department complaining of hemoptysis. A CT scan of the head and neck revealed a hypopharyngeal mass originally favored to be a benign process.Operative endoscopy revealed a previously unseen mucosal ulceration, and subsequent biopsy resulted in the final diagnosis of pleomorphic RMS.Although quite rare, RMS should be considered in the differential diagnosis of a hypopharyngeal mass.
- Published
- 2013
12. Management of the incus body in ossiculoplasty
- Author
-
Travis J. Pfannenstiel, Sam Turner, David P. Mullin, Ben J. Balough, Xianxi Ge, Gregory G. Capra, and Anil N. Shah
- Subjects
medicine.medical_treatment ,Incus ,Decision Making ,Pilot Projects ,Prosthesis ,Vibration ,Temporal bone ,medicine ,Cadaver ,Humans ,Sound pressure ,Incus body ,Round window ,business.industry ,Anatomy ,Laser Doppler velocimetry ,medicine.anatomical_structure ,Ossicular Replacement ,Otorhinolaryngology ,Round Window, Ear ,Middle ear ,Surgery ,business ,Bone Conduction ,Biomedical engineering - Abstract
(1) Evaluate the sound transfer impact of removal of the incus body in ossicular chain reconstruction (OCR) using an incus strut prosthesis. (2) Provide basic science data to assist clinical decision making in ossiculoplasty.Basic science.Cadaveric temporal bone research laboratory.Ossicular chain reconstruction with an incus strut prosthesis was performed on 7 human temporal bones with and without the incus body. The difference in round window membrane (RWM) peak-to-peak displacements (90-dB sound pressure level, 250-8000 Hz) using single-point laser Doppler vibrometry (LDV) was compared with observed baseline, intact ossicular chain values.Comparing OCR using an incus strut prosthesis to an intact ossicular chain across all 7 temporal bones, the largest differences in RWM velocity occurred at 1011 and 2011 Hz. With increasing frequencies, RWM velocities of the OCR approached the intact ossicular chain. Using a Wilcoxon rank-sum test comparing the ossicular chain with and without the incus body showed no statistically significant difference across all frequencies (P = .925). Removing the incus body resulted in improved median RWM velocity (× 10(-2) mm/s) by 0.6 at 1011 Hz and a decrease of 0.6 at 2011 Hz. A rank-sum test to evaluate the difference at 1011 and 2011 Hz did not demonstrate statistical significance.Removal of the incus body in OCR using an incus strut prosthesis did not significantly change sound transfer function of the middle ear relative to its preservation. Our data suggest the impact of the retained mass in OCR to be minimal.
- Published
- 2013
13. Case report: a branchial cleft anomaly presenting as an oropharyngeal mass
- Author
-
David P. Mullin and Meredith Merz
- Subjects
Branchial cleft anomaly ,animal structures ,business.industry ,Fistula ,Oropharynx ,Anatomy ,Pharyngeal Diseases ,medicine.disease ,body regions ,Branchial anomaly ,medicine.anatomical_structure ,Branchial Region ,Otorhinolaryngology ,embryonic structures ,Right posterior ,medicine ,Tonsillar fossa ,Humans ,Cyst ,Female ,Presentation (obstetrics) ,business ,Child ,Sinus (anatomy) - Abstract
Branchial anomalies are common cervical pathologic entities encountered in the field of otolaryngology and are typical in the pediatric and young adult populations. In most cases, these anomalies present as a cyst, sinus, or fistula in a rather stereotypical fashion. When a branchial anomaly deviates from the classic presentation, an improper diagnosis and inadequate management are more likely to occur, leading to an increased recurrence rate. We present a case of a 6-year-old girl with an incidental finding of a right posterior oropharyngeal wall mass, distinctly separate from the tonsillar fossa, which was found on pathologic analysis to be a branchial cleft anomaly. The theories regarding the pathogenesis of branchial anomalies are presented, along with other cases of atypical branchial anomalies.
- Published
- 2011
14. Mycobacterium chelonae infections involving the head and neck
- Author
-
Sumana Jothi, David P. Mullin, and David W. Healy
- Subjects
medicine.medical_specialty ,Maxillary sinus ,Maxillary osteitis ,Mycobacterium chelonae ,Mycobacterium Infections, Nontuberculous ,Clarithromycin ,medicine ,Paranasal Sinus Diseases ,Humans ,Head and neck ,Osteitis ,Aged ,Skull Base ,biology ,business.industry ,Osteomyelitis ,General Medicine ,Maxillary Sinus ,Middle Aged ,Plastic Surgery Procedures ,medicine.disease ,biology.organism_classification ,Combined Modality Therapy ,Abscess ,Surgery ,Anti-Bacterial Agents ,Atypical mycobacterium ,Skull ,medicine.anatomical_structure ,Otorhinolaryngology ,Debridement ,Female ,business - Abstract
Objectives: We describe the manifestations, diagnosis, and treatment of rare head and neck infections caused by Mycobacterium chelonae, including a case of maxillary osteitis and skull base osteomyelitis. Methods: A comprehensive literature search (MEDLINE from 1951; BIOSIS from 1969; EMBASE from 1980) was performed for the presentation, diagnostic evaluation, and outcomes of patients with M chelonae infections. Results: We report 4 cases of M chelonae infection, including a nasal abscess following septorhinoplasty with a cartilaginous graft, a case of chronic unilateral nasal obstruction, and the first reported cases of skull base osteomyelitis and maxillary osteitis secondary to M chelonae. All 4 cases involved immunocompetent individuals. Conclusions: Mycobacterium chelonae should be considered in cases of abscesses that persist despite broad-spectrum intravenous antibiotics, and in cases of maxillary sinusitis with bony involvement that do not respond to traditional treatment methods.
- Published
- 2009
15. Cervical Lymphadenopathy
- Author
-
Kastley, Marvin, Gregory, Capra, and David P, Mullin
- Subjects
Otorhinolaryngology ,Contrast Media ,Humans ,Female ,Surgery ,Middle Aged ,Tuberculosis, Lymph Node ,Tomography, X-Ray Computed - Published
- 2015
- Full Text
- View/download PDF
16. Measurement of nonlinear TM response by scanning LDV
- Author
-
Jim Easter, Ben J. Balough, Mario Pineda, and David P. Mullin
- Subjects
Nonlinear system ,Materials science ,Optics ,business.industry ,business ,Sensory Systems - Published
- 2010
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.