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6 results on '"David J Sturgess"'

1. Pre-operative immune cell numbers and ratios are associated with peri-operative adverse outcomes in transfused patients

Author

Michelle Roets, David J. Sturgess, Ching-Yu Chen, Jaisil E. J. Punnasseril, Lee Jones, Andre A. van Zundert, and Melinda M. Dean

Subjects
immune cells, immune modulation, adverse outcomes, transfusion, biomarkers, Anesthesiology, RD78.3-87.3
Abstract

Background and objectivesTransfusion-related immune modulation (TRIM) and associated adverse outcomes during major surgery are increasingly important to patients and health services internationally. A panel of pre-operative blood tests is an essential part of the pre-operative anaesthetic assessment. This panel of blood tests commonly considers numbers of immune cells (i.e., lymphocytes, monocytes, and neutrophils and cell ratios) that may be used as biomarkers to evaluate and potentially predict post-operative adverse outcomes.DesignThis retrospective data collection from eight hospital databases, within the Royal Brisbane and Women's Hospital, considered only patients who received blood transfusion during surgery (2016–2018) (n = 2,121). The association between pre-operative immune cell numbers and ratios and adverse outcomes were assessed. Adverse outcomes were coded using the International Classification of Diseases-10 (ICD-10) coding which specifically considered transfusion-related immune modulation. Results were adjusted for confounding factors.ResultsAfter adjustment, decreased pre-operative lymphocyte numbers and increased neutrophil/lymphocyte ratio (NLR) were associated with increased odds of developing infection; decreased NLR with decreased odds of developing adverse renal outcomes; and decreased lymphocyte numbers with decreased odds of developing adverse cardiovascular outcomes. Monocyte numbers, neutrophil numbers, and the lymphocyte/monocyte ratio (LMR) were not associated with increased adverse outcomes after adjustment.ConclusionPre-operative lymphocyte numbers and NLR are associated with adverse outcomes during peri-operative transfusion. Future assessment of peri-operative immune modulation should include the assessment of immune cell function and numbers.

Published
2024
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2. Understanding consumer preference for vascular access safety and quality measurement: an international survey

Author

Jessica Schults, Rebecca Paterson, Tricia Kleidon, Marie Cooke, Amanda Ullman, Keith McNeil, Vineet Chopra, Karina Charles, Gillian Ray-Barruel, Nicole Marsh, Clair Sullivan, David J. Sturgess, and Claire Rickard

Subjects
Adult, Cross-Sectional Studies, Health Policy, Surveys and Questionnaires, Humans, Female, Patient Preference, Consumer Behavior, Middle Aged, Vascular Access Devices
Abstract

Objectives The aim of this study was to examine patient perceptions regarding vascular access quality measurement. Methods A web-based, cross-sectional survey was performed using a convenience sample of healthcare consumers with vascular access experience, recruited from September 2019 to June 2020. Survey respondents were asked to rate the perceived importance of 50 vascular access data items, including patient demographics, clinical and device characteristics, and insertion, management and complication data. Data were ranked using a five-point Likert scale (1, least important; 5, most important), and are reported as median values. Respondents proposed additional items and explored broader perspectives using free-text responses, which were analysed using inductive thematic analysis. Results In all, 68 consumers completed the survey. Participants were primarily female (82%), aged 40–49 years (29%) and living in Australia or New Zealand (84%). All respondents indicated that measuring the quality of vascular access care was important. Of the 50 items, 37 (74%) were perceived as ‘most important’ (median score 5), with measures of quality (i.e. outcomes and complications) rated highly (e.g. thrombosis and primary blood stream infection). Participants proposed 16 additional items. ‘Gender’ received the lowest perceived importance score (median score 3). Two themes emerged from the qualitative analysis of broader perspectives: (1) measurement of vascular access device complication severity and associated factors; and (2) patient experience. Conclusion Measuring vascular access quality and safety is important to consumers. Outcome and complication measures were rated ‘most important’, with respondents identifying a need for increased monitoring of their overall vascular access journey through the health system. What is known about the topic? The use of vascular access devices is common among hospitalised patients. Quality surveillance is not standardised, with no incorporation of patient preference. What does this paper add? We identify the data items consumers perceive as valuable to measure related to their vascular access journey; most importantly, consumers perceived the collecting of vascular access data as important. What are the implications for practitioners? Health services can use these data to develop platforms to monitor the quality and safety of vascular access care.

Published
2021

4. List of Contributors

Author

Timothy M Alce, Sumesh Arora, Thearina de Beer, Rinaldo Bellomo, Andrew D Bersten, Tim Bowles, Jeremy P Campbell, Alastair C Carr, Marianne J Chapman, Kai Man Chan, Gordon YS Choi, Christine Chung, Jeremy Cohen, David Collins, D James Cooper, Evelyn Corner, Simon Cottam, Sarah Cox, Lester AH Critchley, Andrew R Davies, Anthony Delaney, Rishi H-P Dhillon, Tavey Dorofaeff, Graeme J Duke, Cyrus Edibam, Evan R Everest, Simon Finfer, Malcolm M Fisher, Oliver J Flower, Carole Foot, David Fraenkel, Steven T Galluccio, A Raffaele De Gaudio, Tony Gin, Charles D Gomersall, Anthony C Gordon, Munita Grover, Pascale Gruber, Anish Gupta, Jonathan M Handy, Sara Hanna, James Hatcher, Felicity H Hawker, Michelle Hayes, Victoria Heaviside, Liz Hickson, Alisa Higgins, Pierre Hoffmeyer, Andrew Holt, Matthew R Hooper, Li C Hsee, Nicholas Ioannou, James P Isbister, Matthias Jacob, Paul James, Paul Cassius Jansz, Mandy O Jones, Gavin M Joynt, James A Judson, Richard Keays, Angus M Kennedy, Ian Kerridge, Geoff Knight, Stephen W Lam, Richard Leonard, Daniel Lew, Alexander M Man Ying Li, Jeffrey Lipman, Pieter HW Lubbert, Peter S Macdonald, David P Mackie, Matthew Maiden, Colin McArthur, Kevin McCaffery, Steve McGloughlin, Johnny Millar, Wai Ka Ming, Fiona H Moffatt, Thomas J Morgan, Peter T Morley, John A Myburgh, Michael MG Mythen, Matthew T Naughton, Alistair D Nichol, Gerry O'Callaghan, Helen I Opdam, Aaisha Opel, Alexander A Padiglione, Simon PG Padley, Valerie Page, Mark Palazzo, Sandra L Peake, Vincent Pellegrino, Michael E Pelly, David Pilcher, Didier Pittet, Kevin Plumpton, Brad Power, Susanna Price, Raymond F Raper, Michael C Reade, Bernard Riley, Shelley D Riphagen, Hayley Robinson, Vineet V Sarode, Hugo Sax, Manoj K Saxena, Oliver R Segal, Frank Shann, Pratik Sinha, Ramachandran Sivakumar, George Skowronski, Anthony J Slater, Martin Smith, Neil Soni, Stephen J Streat, Richard Strickland, David J Sturgess, Christian P Subbe, Joseph JY Sung, Chee Wee Tan, Guido Tavazzi, Peter D (Toby) Thomas, James Tibballs, Luke E Torre, David Treacher, David V Tuxen, Ilker Uçkay, Balasubramanian Venkatesh, Jacqueline EHM Vet, Marcela P Vizcaychipi, Adrian J Wagstaff, Carl S Waldmann, Christopher M Ward, John R Welch, Julia Wendon, Mary White, Ubbo F Wiersema, Timothy Wigmore, Christopher Willars, Wan Tsz Pan Winnie, David M Wood, Duncan LA Wyncoll, and Steve M Yentis

Published
2014
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6. Contributors

Author

Rinaldo Bellomo, Andrew D Bersten, David Bihari, Stephen Brett, Craig Carr, Jeremy Cohen, Frances B Colreavy, D J (Jamie) Cooper, Lester A H Critchley, Andrew R Davies, Anthony Delaney, Karl D Donovan, Graeme Duke, Alan W Duncan, Cyrus Edibam, Evan Everest, Patricia Figgis, Simon Finfer, Malcolm McD Fisher, David Fraenkel, Martyn A H French, Raffaele de Gaudio, Tony Gin, David R Goldhill, Charles D Gomersall N, Munita Grover, Geoff A Gutteridge, Jonathan Handy, Felicity Hawker, Michelle Hayes, Victoria Heaviside, Peter V van Heerden, Robert D Henning, Bernard E F Hockings, Andrew Holt, Anwar Hussein, James P Isbister, Mandy Oade Jones, Gavin M Joynt, James A Judson, Richard T Keays, Warwick D Ngan Kee, Angus M Kennedy, Geoff Knight, Richard Leonard, Jeffrey Lipman, David P Mackie, Neil T Matthews, Colin McArthur, Angela McLuckie, Fiona Herris Moffatt, Cliff J Morgan, Thomas John Morgan, Peter T Morley, Raymond G Morris, Blair Munford, John A Myburgh, Michael Mythen, Matthew T Naughton, Alistair D Nichol, Helen Ingrid Opdam, Simon P G Padley, Mark Palazzo, Marcus Peck, Michael E Pelly, David V Pilcher, Didier Pittet, Brad Power, Raymond F Raper, Bernard Riley, John E Sanderson, Hugo Sax, Frank A Shann, Ramachandran Sivakumar, Elizabeth Sizer, George A Skowronski, Anthony J Slater, Martin Smith, Neil Soni, Stephen J Streat, David J Sturgess, Joseph J Y Sung, Ian K S Tan, Chris Theaker, James Tibballs, David Treacher, David V Tuxen, Richard N Upton, Balasubramanian Venkatesh, Adrian T J Wagstaff, Carl S Waldmann, John R Welch, Julia Wendon, Steve Wesselingh, Ubbo F Wiersema, Duncan LA Wyncoll, and Steve M Yentis

Published
2009
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