Search

Your search keyword '"Davalos, Verónica"' showing total 22 results
Start Over Author "Davalos, Verónica"
22 results on '"Davalos, Verónica"'

1. The spatial landscape of cancer hallmarks reveals patterns of tumor ecological dynamics and drug sensitivity

Author

Grande, Enrique, Alonso-Gordoa, Teresa, Álvarez-Maestro, Mario, Andrada, Elena, Azueta, Ainara, Javier Burgos, Raquel Benítez, Castellano, Daniel, Climent, M. Angel, Domínguez, Mario, Albert Font, Ignacio Durán, Galante, Isabel, Galván, Patricia, García, Juan F., García del Muro, Xavier, Guerrero-Ramos, Félix, Malats, Núria, Marqués, Miriam, Maroto, Pablo, Martínez de Villarreal, Jaime, Moreno-Oya, Ane, Paramio, Jesús M., Pinto, Alvaro, Prat, Aleix, Puente, Javier, Reig, Oscar, Real, Francisco X., Sibai, Mustafa, Cervilla, Sergi, Grases, Daniela, Musulen, Eva, Lazcano, Rossana, Mo, Chia-Kuei, Davalos, Veronica, Fortian, Arola, Bernat, Adrià, Romeo, Margarita, Tokheim, Collin, Barretina, Jordi, Lazar, Alexander J., Ding, Li, Esteller, Manel, Bailey, Matthew H., and Porta-Pardo, Eduard

Published
2025
Full Text
View/download PDF

3. Epigenetic profiling linked to multisystem inflammatory syndrome in children (MIS-C): A multicenter, retrospective study

Author

Davalos, Veronica, García-Prieto, Carlos A., Ferrer, Gerardo, Aguilera-Albesa, Sergio, Valencia-Ramos, Juan, Rodríguez-Palmero, Agustí, Ruiz, Montserrat, Planas-Serra, Laura, Jordan, Iolanda, Alegría, Iosune, Flores-Pérez, Patricia, Cantarín, Verónica, Fumadó, Victoria, Viadero, Maria Teresa, Rodrigo, Carlos, Méndez-Hernández, Maria, López-Granados, Eduardo, Colobran, Roger, Rivière, Jacques G., Soler-Palacín, Pere, Pujol, Aurora, and Esteller, Manel

Published
2022
Full Text
View/download PDF

5. Epigenome-wide association study of COVID-19 severity with respiratory failure

Author

Castro de Moura, Manuel, Davalos, Veronica, Planas-Serra, Laura, Alvarez-Errico, Damiana, Arribas, Carles, Ruiz, Montserrat, Aguilera-Albesa, Sergio, Troya, Jesús, Valencia-Ramos, Juan, Vélez-Santamaria, Valentina, Rodríguez-Palmero, Agustí, Villar-Garcia, Judit, Horcajada, Juan P., Albu, Sergiu, Casasnovas, Carlos, Rull, Anna, Reverte, Laia, Dietl, Beatriz, Dalmau, David, Arranz, Maria J., Llucià-Carol, Laia, Planas, Anna M., Pérez-Tur, Jordi, Fernandez-Cadenas, Israel, Villares, Paula, Tenorio, Jair, Colobran, Roger, Martin-Nalda, Andrea, Soler-Palacin, Pere, Vidal, Francesc, Pujol, Aurora, and Esteller, Manel

Published
2021
Full Text
View/download PDF

6. Epigenetic loss of m1A RNA demethylase ALKBH3 in Hodgkin lymphoma targets collagen, conferring poor clinical outcome

Author

Esteve-Puig, Rosaura, Climent, Fina, Piñeyro, David, Domingo-Domènech, Eva, Davalos, Veronica, Encuentra, Maite, Rea, Anna, Espejo-Herrera, Nadia, Soler, Marta, Lopez, Miguel, Ortiz-Barahona, Vanessa, Tapia, Gustavo, Navarro, José-Tomás, Cid, Joan, Farré, Lourdes, Villanueva, Alberto, Casanova, Isolda, Mangues, Ramon, Santamarina-Ojeda, Pablo, Fernández, Agustín F., Fraga, Mario F., Piris, Miguel Angel, Kol, Nitzan, Avrahami, Chen, Moshitch-Moshkovitz, Sharon, Rechavi, Gideon, Sureda, Anna, and Esteller, Manel

Published
2021
Full Text
View/download PDF

7. Epigenetic prediction of response to anti-PD-1 treatment in non-small-cell lung cancer: a multicentre, retrospective analysis

Author

Duruisseaux, Michäel, Martínez-Cardús, Anna, Calleja-Cervantes, Maria E, Moran, Sebastian, Castro de Moura, Manuel, Davalos, Veronica, Piñeyro, David, Sanchez-Cespedes, Montse, Girard, Nicolas, Brevet, Marie, Giroux-Leprieur, Etienne, Dumenil, Coraline, Pradotto, Monica, Bironzo, Paolo, Capelletto, Enrica, Novello, Silvia, Cortot, Alexis, Copin, Marie-Christine, Karachaliou, Niki, Gonzalez-Cao, Maria, Peralta, Sergio, Montuenga, Luis M, Gil-Bazo, Ignacio, Baraibar, Iosune, Lozano, Maria D, Varela, Mar, Ruffinelli, Jose C, Palmero, Ramon, Nadal, Ernest, Moran, Teresa, Perez, Lidia, Ramos, Immaculada, Xiao, Qingyang, Fernandez, Agustin F, Fraga, Mario F, Gut, Marta, Gut, Ivo, Teixidó, Cristina, Vilariño, Noelia, Prat, Aleix, Reguart, Noemi, Benito, Amparo, Garrido, Pilar, Barragan, Isabel, Emile, Jean-François, Rosell, Rafael, Brambilla, Elisabeth, and Esteller, Manel

Published
2018
Full Text
View/download PDF

13. An epigenetic switch controls an alternative NR2F2 isoform 2 that unleashes a metastatic program in melanoma

Author

Davalos, Verónica, Lovell, Claudia, von Itter, Richard, Dolgalev, Igor, Agrawal, Praveen, Baptiste, Gillian, Kahler, David, Sokolova, Elena, Moran, Sebastian, Piqué, Laia, Vega-Saenz de Miera, Eleazar, Fontanals-Cirera, Barbara, Karz, Alcida, Tsirigos, Aristotelis, Yun, Chi, Darvishian, Farbod, Etchevers, Heather, Osman, Iman, Esteller, Manel, Schober, Markus, Hernando, Eva, Department of Pathology, New York University Grossman School of Medicine, NY 10016, USA, Applied Bioinformatics Laboratories, New York University Grossman School of Medicine, NY 10016, USA, Bellvitge Biomedical Research Institute, Partenaires INRAE, Josep Carreras Leukaemia Research Institute (IJC), Badalona, Barcelona, Catalonia, Spain, New York University School of Medicine (NYU Grossman School of Medicine), National Tsing Hua University [Hsinchu] (NTHU), City University of Hong Kong [Hong Kong] (CUHK), Marseille medical genetics - Centre de génétique médicale de Marseille (MMG), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Marseille Maladies Rares (MarMaRa), Aix Marseille Université (AMU), Interdisciplinary Melanoma Cooperative Group, Perlmutter Cancer Center, New York University School of Medicine, NY 10016, USA (NYUSM), Institució Catalana de Recerca i Estudis Avançats (ICREA), Josep Carreras Leukaemia Research Institute (IJC), Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Universitat de Barcelona (UB), New York University [New York] (NYU), NYU System (NYU), and We thank the NYU Experimental Pathology Core, the NYU Genome Technology Center, the NYUCenter for Biospecimen Research and Development, and the Small Animal Imaging core, all partially supported by the Laura and Isaac Perlmutter Cancer Center Support Grant (CCSG) NIH/NCI P30CA016087 (NIH/NCI), and National Institute of Health S10 Grants NIH/ORIP S10OD01058 and S10OD018338. We thank the High Throughput Biology Core partially funded by P30CA16087 and NYSTEM Contract C026719. V.D. was supported by the People Program (Marie Curie Actions) of the European Union's Seventh Framework Program (FP7-PEOPLE30 2013-IOF) under REA grant agreement n° PIOF-GA-2013-623443. This work was funded by NCI/NIH R01CA202027, R01CA274100, P01CA206980 and NYU Melanoma SPOREP50CA225450 (PI: I.O).

Subjects
[SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics, [SDV]Life Sciences [q-bio], [SDV.CAN]Life Sciences [q-bio]/Cancer, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, [SDV.MHEP.DERM]Life Sciences [q-bio]/Human health and pathology/Dermatology
Abstract

International audience; Metastatic melanoma develops once transformed melanocytic cells begin to de-differentiate into migratory and invasive melanoma cells with neural crest cell (NCC)-like and epithelial-tomesenchymal transition (EMT)-like features. However, it is still unclear how transformed melanocytes assume a metastatic melanoma cell state. Here, we define DNA methylation changes that accompany metastatic progression in melanoma patients and discover Nuclear Receptor Subfamily 2 Group F, Member 2 – isoform 2 (NR2F2-Iso2) as an epigenetically regulated metastasis driver. NR2F2-Iso2 is transcribed from an alternative transcriptional start site (TSS) and it is truncated at the N-terminal end which encodes the NR2F2 DNA-bindingdomain. We find that NR2F2-Iso2 expression is turned off by DNA methylation when NCCs differentiate into melanocytes. Conversely, this process is reversed during metastatic melanoma progression, when NR2F2-Iso2 becomes increasingly hypomethylated and re-expressed. Our functional and molecular studies suggest that NR2F2-Iso2 drives metastatic melanomaprogression by modulating the activity of full-length NR2F2 (Isoform 1) over EMT- and NCC-associated target genes. Our findings indicate that DNA methylation changes play a crucial role during metastatic melanoma progression, and their control of NR2F2 activity allows transformed melanocytes to acquire NCC-like and EMT-like features. This epigenetically regulated transcriptional plasticity facilitates cell state transitions and metastatic spread.

Published
2023
Full Text
View/download PDF

19. Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing

Author

Melo, Sonia, Villanueva, Alberto, Moutinho, Catia, Davalos, Veronica, Spizzo, Riccardo, Ivan, Cristina, Rossi, Simona, Setien, Fernando, Casanovas, Oriol, Simo-Riudalbas, Laia, Carmona, Javier, Carrere, Jordi, Vidal, August, Aytes, Alvaro, Puertas, Sara, Ropero, Santiago, Kalluri, Raghu, Croce, Carlo M., Calin, George A., Esteller, Manel, and Dahlberg, James E.

Published
2011

Catalog

Books, media, physical & digital resources
See catalog results