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Background and Aim: The vast majority of diseases have a haematological finding known as thrombocytopenia, which can be found in the hemogram of affected individuals. The objective is to investigate the common causes of acute fever with thrombocytopenia, such as Dengue fever, Chikungunya fever, Malaria, and Leptospirosis, with a particular focus on the Indian subcontinent, using laboratory and immunological tests that are pertinent to the situation. Material and Methods: For the purpose of the study, a total of fifty patients were recruited. A semi-structured questionnaire based on interviews was developed under the direction of an expert after a review of the relevant literature was conducted. All consecutive hospitalized patients who had fevers that lasted for less than seven days and thrombocytopenia were included in the study. The patients were then divided into three distinct categories after the classification process. Accuracy of a diagnostic test can be evaluated by computing sensitivity, specificity, predictive values, and likelihood ratios. Results: A total of 58% of the cases were brought on by dengue fever,32% were brought on by malaria, 8% were brought on by other fevers associated with thrombocytopenia, and two percent were brought on by chikungunya. The younger age group is more likely to experience fever with thrombocytopenia, and males are more likely to be affected than females. The patients who were between the ages of 12 and 30 made up 74% of the total population. The total number of patients who experienced bleeding was four. Conclusion: The incidence of dengue fever is the most common cause. There was a seasonal variation in the cases, with the majority of cases occurring between the months of June and September. Fever and thrombocytopenia are the most common symptoms of dengue fever, which is the most common disease. [ABSTRACT FROM AUTHOR]

Background: In developing countries, the widespread use of organophosphorus compounds (OPCs) has been accompanied by increasing incidence of poisoning with these agents, both suicidal and accidental. This is attributed mainly to their easy availability, indiscriminate handling, storage and lack of knowledge about the serious consequences of poisoning. Of the various substance used for suicidal attempts in India, OPCs form a significant group. Since the clinical manifestation of OPC poisoning is diverse ranging from mild symptoms to fatal complications in the course of time, we need proper management of the situation. Materials and methods: Present study included 42 patients with Organophosphorus poisoning admitted in B.J. Medical College, and Civil Hospital Ahmedabad. This study was carried out from June 2018 to June 2019. Patients were managed as per standard protocols of O P poisoning. We also checked for various parameters on like cholinesterase level, complete blood counts, renal function test with electrolytes, liver function test. Results: In this study, majority of patients fell in 20-30 years of age group with male predominance. Most common clinical features were vomiting, miosis and giddiness. Majority of the patients belonged to mild grade. The average s.cholinesterase level was low as severity increases. More doses of PAM and atropine were required in severe poisoning. Most common complication was respiratory paralysis. Death was more in severe poisoning. Conclusion: OPC is one of the most common poisoning in India. In patients of OP poisoning presenting symptoms and s.ChE level directly correlated with severity. Therapeutic required dose of PAM and atropine are different in different grade of severity. Survival amongst patients is definitely better if atropine and PAM are being given with Mechanical ventilator support in cases of respiratory insufficiency. [ABSTRACT FROM AUTHOR]