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Copyright of Revista Brasileira de Higiene e Sanidade Animal is the property of Associacao Cientifica dos Medicos Veterinarios do Ceara and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Veterinaria Brasilica is the property of Acta Veterinaria Brasilica and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Veterinaria Brasilica is the property of Acta Veterinaria Brasilica and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Brasileira de Higiene e Sanidade Animal is the property of Associacao Cientifica dos Medicos Veterinarios do Ceara and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Background: In dogs, abdominal testes have higher risk of malignant transformation, and the Sertoli cell tumor is the most common type of testicular cancer in the species. This neoplasia can lead to an increase on estrogen production, causing a paraneoplastic feminization syndrome with dermatologic, behavioral and blood repercussions. When located inside the abdomen, the Sertoli cell tumor can compress adjacent organs, worsening the prognosis. Thus, this study aimed to report a case of an intra-abdominal Sertoli cell tumor in a dog associated to multiple organic complications. Case: A 4-year-old male Shih-tzu was admitted at the Veterinary Hospital of Universidade Federal Rural do Semi-Árido (UFERSA), with a history of abdominal cryptorchidism and the development of dermatological signs, such as alopecia and hyperpigmentation, with an evolution of two months. At physical examination it was observed alopecia on lumbosacral region and on hind limbs, hyperpigmentation, gynecomastia and pendulous prepuce, suggestive of feminization syndrome. A firm mass was palpated on caudal abdomen. The following exams were requested: complete blood cell count, serum biochemistry (alanine aminotransferase, alkaline phosphatase, creatinine and urea), abdominal ultrasonography and fine needle aspiration cytology of the abdominal mass. Hematological and biochemistry profile were within the normal range for the species. On the ultrasonography, regular and rounded structures were observed, suggesting ectopic testes (left testis: 2.37 x 2.95 cm; right testis: 1.92 x 1.38 cm). The left testis presented characteristics of malignant transformation. The cytology of the abdominal mass suggested Sertoli cell tumor. The dog was submitted to an exploratory laparotomy. The right testis was atrophied and its orchiectomy was performed. The contralateral testis was completed adhered to great vessels, such as abdominal aorta and caudal vena cava, and also to adjacent viscera. Thus, the exeresis of the tumor was not possible and fragments of the mass were collected and referred to histopathology. The left testicle presented tumoral polyedric cells, alonged at the longitudinal axis, propagating disorderly, and with central rounded nucleus, and a clear and vacuolar cytoplasm. It was also observed desmoplasia, anisocytosis, anisocariasis, nuclear atypia and evident nucleoli. The mitotic index was less than one mitotic figure/40x, with aberrant mitotic figures. The histopathological evaluation was compatible with Sertoli cell tumor, confirming the presumptive diagnosis. Chemotherapy was proposed, but the animal's owner refused. After four months the dog was readmitted presenting a series of complications due to the tumor growth, including bone marrow hypoplasia, gallbladder compression and hydronephrosis. Because of the poor prognosis and severity of complications a decision to euthanize the animal was made. Discussion: Intra-abdominal Sertoli cell tumors have good prognosis when the diagnosis and surgical treatment are made early. Nevertheless, this neoplasia can be associated to critical and irreversible damages to various organs, such as bone marrow hypoplasia, and compression of abdominal organs when the tumor grows rapidly and invades adjacent structures, making the complete surgical exeresis impossible. Therefore, the orchiectomy of cryptorchidic dogs is recommended as soon as possible to prevent the development of testicular cancer in these animals. [ABSTRACT FROM AUTHOR]

Background: Rare studies have described the association of hematopoietic tumors and canine visceral leishmaniosis, however the association between the parasitary disease and neoplasia is still not well established in dogs. Thus, the aim of the present study was to report a case of acute myeloid leukemia (AML) in a dog infected by Leishmania spp. and other infectious agents. Case: A 8-year-old, male Poodle, was brought to the Veterinary Hospital from Universidade Federal Rural do Semi-Árido. The dog had a history of recurrent tick-borne diseases, such as anaplasmosis, over the previous ten months. On physical examination, pale mucosa, enlargement of popliteal lymph nodes, onychogryphosis, purulent nasal discharge, and bilateral blepharitis with purulent discharge were observed. The dog was skinny and infested with ticks. The blood cell count revealed normocytic, normochromic anemia and leukocytosis (38.000/mm3) with neutrophilia (30.020/mm3). Serum biochemical tests demonstrated hyperproteinemia due to hyperglobulinemia, hypoalbuminemia, and an albumin:globulin ratio of 0.30. The immunochromathographic test for leishmaniasis was negative. The alterations observed in the bone marrow cytological analysis were suggestive of AML, and Anaplasma spp., Hepatozoon spp., and amastigote forms of Leishmania spp. were observed inside bone marrow cells. After diagnosis, a decision to euthanize the animal was made. Discussion: Few studies have demonstrated the presence of hematopoietic neoplasia in dogs chronically and simultaneously infected with multiple pathogens. A case of multiple myeloma in a dog associated with infection by Ehrlichia canis, A. phagocytophilum, L. infantum, and Dirofilaria immitis is described. Another study reported B-cell lymphoma in a dog with E. canis and Histoplasma capsulatum infection. The pathogenesis of AML in the reported dog might be associated with continuous antigenic stimulation and chronic inflammation caused by the infectious agents. The pathological changes in bone marrow caused by Leishmania are well described, and different combinations of hypoplasia, hyperplasia, or dysplasia of all hematopoietic lineages can occur. The inflammation and chronic stimulation of hematopoiesis can lead to an increased risk of changes in the genetic material of the hematopoietic precursor cells. Thus, there is an increased chance of generation of mutated clones, resulting in hematopoietic malignancies. Immunosuppression is a common condition present in numerous types of neoplasia, especially in those with hematopoietic origins, which increases the vulnerability to opportunistic diseases. In humans, the presence of concomitant neoplasia and leishmaniasis is well documented, However, there are very few veterinary medicine studies on the association between neoplasia and canine visceral leishmaniosis. Cases of hematopoietic tumors, such as multiple myeloma, and multicentric, cutaneous, and cardiac lymphomas, have been described in dogs with leishmaniasis. To the best of our knowledge, this is possibly the first report implicating pathogens of the genera Leishmania, Anaplasma and Hepatozoon as contributors in the etiopathogenesis of AML in the studied animal. Based on all clinical and laboratory findings, we theorize that the prolonged antigenic stimulation and chronic inflammation caused by the infectious agents played a crucial role in the development of leukemia in the dog. [ABSTRACT FROM AUTHOR]

Canine lymphoma is a hematopoietic neoplasm that can affect different tissues. Its classification is performed according to cellular morphology, clinical stage, immunophenotyping, and anatomical location. However, in some cases, an oncopathy might be in an advanced stage with a plain organic spread, making it impossible to determine the initially affected tissue, which is a rare situation in animals. Thus, a case of metastatic lymphoma, of unknown primary origin, was described in a four-year-old Rottweiler bitch with multiple nodular subcutaneous proliferations. Hematological, biochemical, thoracic radiography, and abdominal ultrasound tests were performed, as well as a cytopathological examination of subcutaneous lesions and bone marrow. Hematologic findings determined anemia, lymphopenia, and thrombocytopenia. The thoracic radiography revealed multiple nodular masses. Cytopathological examination revealed infiltration of malignant lymphocytes into the subcutaneous nodules and into the bone marrow. The dog was euthanized and submitted to necroscopic examination, in which multiple nodules were found in the subcutaneous region, lung, pericardium, gastrointestinal tract and in the skeletal musculature, in addition to lymphadenopathy. Fragments of the affected structures were collected for later histopathological and immunohistochemical evaluation. Histopathological examination revealed the presence of neoplastic cells compatible with diffuse lymphoma, which was positively immunolabelled for T-cell lymphoma. Based on clinical-pathological findings and other complementary tests, a diagnosis of diffuse T-cell lymphoma of unknown primary origin was made. In order to classify hematopoietic neoplasms, it is essential to perform different laboratory tests. However, determination of origin becomes difficult when such an oncological disease presents an advanced stage. [ABSTRACT FROM AUTHOR]

Copyright of Revista Brasileira de Higiene e Sanidade Animal is the property of Associacao Cientifica dos Medicos Veterinarios do Ceara and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Brasileira de Higiene e Sanidade Animal is the property of Associacao Cientifica dos Medicos Veterinarios do Ceara and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Brasileira de Higiene e Sanidade Animal is the property of Associacao Cientifica dos Medicos Veterinarios do Ceara and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

O canino geriátrico geralmente tem combinação de múltiplas enfermidades. Relatou-se endocrinopatia e oncopatia em um cão senil. Um canino, macho, dez anos, possuía massa inguinal, poliúria, polidipsia e polifagia. Realizou-se ultrassom abdominal, teste de supressão com dexametasona e citologia inguinal. Na imaginologia havia acréscimo das adrenais e fígado. A análise hormonal indicou hiperadrenocorticismo. A citologia revelou seminoma. Em cães senis, deve-se atentar para afecções simultâneas, em distintos órgãos. [ABSTRACT FROM AUTHOR]

Copyright of Revista Brasileira de Higiene e Sanidade Animal is the property of Associacao Cientifica dos Medicos Veterinarios do Ceara and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Background: Canine hemangiosarcoma is a malignant neoplasm of endothelial cells. Such tumor has most commonly its primary location in the spleen, right atrium, subcutaneous tissue and liver. In general, metastases occur in the liver, omentum, mesentery and lung. The nervous system may be a metastasis site, but with rare spinal cord involvement. This paper aims at the description of canine cutaneous hemangiosarcoma with metastasis to the central nervous system. Case: A dog presented history of skin neoplasia. The patient underwent physical examination, which detected an exophytic tumor in the foreskin. Needle aspiration of the lesion was carried out, suggesting the presence of malignant neoplasm of mesenchymal origin. So, the lesion surgical excision was the option. Before the procedure, complementary preoperative examinations of the patient were required. Those corresponded to chest radiographs, abdominal ultrasound, complete blood count, serum urea, creatinine, alanine aminotransferase, aspartate aminotransferase and total protein. The image diagnostic of the thoracic and abdominal cavities showed no noteworthy changes. The hematology and serum biochemistry were normal. The tumor obtained during surgery was sent for histopathological analysis, whose diagnosis corresponded to hemangiosarcoma. Chemotherapy treatment was not possible in the animal. Nine months after the surgery, alterations in the canine movement were detected as well as postural reactions of the right forelimb, with paresis and reduced proprioception of the same. Hyperesthesia was also found in the spine, in the cervical and thoracic segments. Due to the patient's clinical condition, euthanasia was recommended. The animal was sent for autopsy, where the main macroscopic lesions were dark red areas in the left brain and spinal cord compression by a tumor between the bodies of the seventh cervical vertebra and the first chest one. All material was sent for histopathological examination, which revealed the presence of hemangiosarcoma in the structures examined, suggesting metastasis to the central nervous system from the primary cutaneous site. Discussion: The majority of dogs with cutaneous hemangiosarcoma, during the initial clinical presentation, have already presented a primary tumor in another organ. However, in the present report, there was an inversion of this quotation, since the initial site of the tumor probably corresponded to the skin as, during the first approach, the patient's chest radiographs and abdominal ultrasound did not reveal metastastic injuries. Also, at that time, the dog did not exhibit clinical signs related to tumor spread, unlike the symptoms observed after nine months. To hemangiosarcomas with location in the frontal lobe of the brain, contralateral postural reaction deficits can be observed. Such statement may justify, for the case under discussion, the association of the lesions in the left cerebral hemisphere with disabilities in the proprioception in the right forelimb. Hemangiosarcomas of the spine with extradural location cause gradual compression of the spinal cord and thus favor the development of progressive myelopathy symptoms. This quote could explain the spine hyperesthesia and the monoparesis reported in the animal. The histopathology of skin tumors is essential to establish the definitive diagnosis and for better understanding of future pathologies. [ABSTRACT FROM AUTHOR]

A peritonite infecciosa felina (PIF) é dividida nas formas efusiva e não efusiva. Alguns animais têm sinais de ambas, correspondendo o tipo misto. Relataram-se os achados patológicos de um caso de PIF mista. Um felino foi encaminhado para necropsia. O material foi inspecionado e enviado para histopatologia. A macroscopia observou-se serosites fibrinosas, efusões abdominal e torácica, além de granulomas viscerais. A microscopia foi compatível com PIF e ao associar com a macroscopia, concluiu-se uma apresentação mista da doença. Na suspeição de PIF devese incluir a forma mista na classificação desta enfermidade. [ABSTRACT FROM AUTHOR]

Neoplasias auriculares em cães são raras. Relatou-se um carcinoma de glândulas ceruminosas nessa espécie. Uma cadela possuía lesão na orelha direita. Submeteu-se a paciente ao exame físico. Optou-se por biopsia excisional. A amostra foi enviada para histopatologia. Observou-se nódulo no ramo vertical do canal auditivo externo direito. A histopatologia detectou carcinoma de glândulas ceruminoso. Este deve ser considerado em canídeos com massas no meato acústico externo. [ABSTRACT FROM AUTHOR]

Copyright of Archives of Veterinary Science is the property of Archives of Veterinary Science and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Archives of Veterinary Science is the property of Archives of Veterinary Science and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Biociências is the property of EDIPUCRS - Editora Universitaria da PUCRS and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Hemimelia is uncommon in the feline species, and it is equivalent to hypoplasia or agenesis of paired bones. The study aimed to report a case of radius agenesis in a cat. A cat had changes in the forelimbs. The patient underwent physical examination, followed by radiographic evaluation. The forelimbs had rotational deformity, medially bent. Radiographs showed bilateral absence of the radius. The description of total radius hemimelia (agenesis) is essential to alert to its occurrence in feline clinical medicine. [ABSTRACT FROM AUTHOR]

Copyright of Archives of Veterinary Science is the property of Archives of Veterinary Science and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Archives of Veterinary Science is the property of Archives of Veterinary Science and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Archives of Veterinary Science is the property of Archives of Veterinary Science and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Archives of Veterinary Science is the property of Archives of Veterinary Science and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)