47 results on '"Danober, Laurence"'
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2. New insights in the development of positive allosteric modulators of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors belonging to 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxides: Introduction of (mono/difluoro)methyl groups at the 2-position of the thiadiazine ring
3. Exploring thienothiadiazine dioxides as isosteric analogues of benzo- and pyridothiadiazine dioxides in the search of new AMPA and kainate receptor positive allosteric modulators
4. In vivo pharmacological profile of S 38093, a novel histamine H3 receptor inverse agonist
5. New procognitive enhancers acting at the histamine H3 and AMPA receptors reverse natural forgetting in mice: comparisons with donepezil and memantine in the object recognition task
6. New Insights In The Development of Positive Allosteric Modulators of A-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid (AMPA) Receptors Belonging To 3,4-Dihydro-2H-1,2,4-Benzothiadiazine 1,1-Dioxides: Introduction of (Mono/Difluoro)Methyl Groups At The 2-Position of the Thiadiazine Ring
7. Molecular characterization of the AMPA-receptor potentiator S70340 in rat primary cortical culture: Whole-genome expression profiling
8. Modulatory effects of S 38232, a non α-7 containing nicotine acetylcholine receptor agonist on network activity in the mouse hippocampus
9. Synthesis and pharmacological evaluation of a second generation of pyridothiadiazine 1,1-dioxides acting as AMPA potentiators
10. Development of Thiochroman Dioxide Analogues of Benzothiadiazine Dioxides as New Positive Allosteric Modulators of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors
11. DRUG FOCUS: S 18986: A Positive Allosteric Modulator of AMPA-Type Glutamate Receptors Pharmacological Profile of a Novel Cognitive Enhancer
12. P2-065: IN VITRO PHARMACOLOGICAL CHARACTERIZATION OF S68890, AN ALLOSTERIC MODULATOR OF ALPHA7 NICOTINIC RECEPTORS
13. P3-043: COGNITIVE PROFILE OF S 68890, AN ALLOSTERIC MODULATOR OF ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTORS
14. Quantitative assessment of oligomeric amyloid β peptide binding to α7 nicotinic receptor
15. Pharmacological characterisation of S 47445, a novel positive allosteric modulator of AMPA receptors
16. COGNITIVE PROFILE OF S 68890, AN ALLOSTERIC MODULATOR OF ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTORS
17. IN VITRO PHARMACOLOGICAL CHARACTERIZATION OF S68890, AN ALLOSTERIC MODULATOR OF ALPHA7 NICOTINIC RECEPTORS
18. Synthesis and Pharmacology of Mono-, Di-, and Trialkyl-Substituted 7-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxides Combined with X-ray Structure Analysis to Understand the Unexpected Structure–Activity Relationship at AMPA Receptors
19. P2-312: In vivo characterization of s44858, a positive allosteric modulator of ampa receptors and GluN2B selective non-competitive nmda antagonist
20. P4-172: S 44858, a positive allosteric modulator of ampa receptors and GluN2B selective nmda receptors antagonist, prevents the disruption of synaptic plasticity induced by Aβ oligomers
21. P2-311: In vitro characterization of s44858: A positive allosteric modulator of ampa receptors and GluN2B selective non-competitive nmda receptors antagonist
22. Positive Allosteric Modulators of 2-Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic Acid Receptors Belonging to 4-Cyclopropyl-3,4-dihydro-2H-1,2,4-pyridothiadiazine Dioxides and Diversely Chloro-Substituted 4-Cyclopropyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxides
23. Thermodynamic Characterization of New Positive Allosteric Modulators Binding to the Glutamate Receptor A2 Ligand-Binding Domain:Combining Experimental and Computational Methods Unravels Differences in Driving Forces
24. Thermodynamic Characterization of New Positive Allosteric Modulators Binding to the Glutamate Receptor A2 Ligand-Binding Domain: Combining Experimental and Computational Methods Unravels Differences in Driving Forces
25. Positive Allosteric Modulators of 2-Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic Acid Receptors Belonging to 4-Cyclopropyl-3,4-dihydro-2H-1,2,4-pyridothiadiazine Dioxides and Diversely Chloro-Substituted 4-Cyclopropyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxides
26. P4-001: CHANGES IN FRONTOCORTICAL INTERSTITIAL FLUID LEVELS OF BETA-AMYLOID AND TAU PROTEIN IN TRANSGENIC MICE MODELS OF ALZHEIMER'S DISEASE
27. Synthesis, Pharmacological and Structural Characterization, and Thermodynamic Aspects of GluA2-Positive Allosteric Modulators with a 3,4-Dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxide Scaffold
28. Development of Thiophenic Analogues of Benzothiadiazine Dioxides as New Powerful Potentiators of 2-Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic Acid (AMPA) Receptors
29. New substituted aryl esters and aryl amides of 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxides as positive allosteric modulators of AMPA receptors
30. S 44858, a positive allosteric modulator of ampa receptors and GluN2B selective nmda receptors antagonist, prevents the disruption of synaptic plasticity induced by Aβ oligomers
31. In vitro characterization of s44858: A positive allosteric modulator of ampa receptors and GluN2B selective non-competitive nmda receptors antagonist
32. In vivo characterization of s44858, a positive allosteric modulator of ampa receptors and GluN2B selective non-competitive nmda antagonist
33. New Fluorinated 1,2,4-Benzothiadiazine 1,1-Dioxides: Discovery of an Orally Active Cognitive Enhancer Acting through Potentiation of the 2-Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic Acid Receptors
34. Design, Synthesis, and Pharmacology of Novel 7-Substituted 3,4-Dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxides as Positive Allosteric Modulators of AMPA Receptors
35. P1-415 S18986, enhances BDNF expression in rat primary neuronal cultures
36. P1-406 S 18986, positive allosteric modulator of AMPA receptors as a novel cognition enhancer in rodents
37. CHANGES IN FRONTOCORTICAL INTERSTITIAL FLUID LEVELS OF BETA-AMYLOID AND TAU PROTEIN IN TRANSGENIC MICE MODELS OF ALZHEIMER'S DISEASE
38. Synaptic mechanisms of NMDA-mediated hyperpolarization in lateral amygdaloid projection neurons
39. Thermodynamic Characterization of New Positive AllostericModulators Binding to the Glutamate Receptor A2 Ligand-Binding Domain:Combining Experimental and Computational Methods Unravels Differencesin Driving Forces.
40. Positive Allosteric Modulatorsof 2-Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionicAcid Receptors Belonging to 4-Cyclopropyl-3,4-dihydro-2H-1,2,4-pyridothiadiazine Dioxides and DiverselyChloro-Substituted...
41. Mechanisms and functional significance of a slow inhibitory potential in neurons of the lateral amygdala
42. C-fos expression after single and kindled audiogenic seizures in Wistar rats
43. Synthesis, Pharmacologicaland Structural Characterization,and Thermodynamic Aspects of GluA2-Positive Allosteric Modulatorswith a 3,4-Dihydro-2H-1,2,4-benzothiadiazine1,1-Dioxide Scaffold.
44. Development of ThiophenicAnalogues of BenzothiadiazineDioxides as New Powerful Potentiators of 2-Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionicAcid (AMPA) Receptors.
45. Effects of cholinergic drugs on genetic absence seizures in rats
46. S 18986: A Positive Allosteric Modulator of AMPA-Type Glutamate Receptors Pharmacological Profile of a Novel Cognitive Enhancer.
47. Synaptic mechanisms of NMDAmediated hyperpolarization in lateral amygdaloid projection neurons
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